Detailed information for compound 1183338

Basic information

Technical information
  • TDR Targets ID: 1183338
  • Name: N,N-dimethyl-2-[(R)-(4-methylphenyl)-phenylme thoxy]ethanamine
  • MW: 269.381 | Formula: C18H23NO
  • H donors: 0 H acceptors: 0 LogP: 3.67 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCO[C@@H](c1ccc(cc1)C)c1ccccc1)C
  • InChi: 1S/C18H23NO/c1-15-9-11-17(12-10-15)18(20-14-13-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3/t18-/m1/s1
  • InChiKey: PJUYQWIDNIAHIZ-GOSISDBHSA-N  

Network

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Synonyms

  • N,N-dimethyl-2-[(R)-(4-methylphenyl)-phenyl-methoxy]ethanamine
  • dimethyl-[2-[(R)-(4-methylphenyl)-phenyl-methoxy]ethyl]amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Cavia porcellus Histamine H1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis biogenic amine (5HT) receptor Histamine H1 receptor   488 aa 485 aa 26.4 %
Schistosoma mansoni biogenic amine (dopamine) receptor Histamine H1 receptor   488 aa 498 aa 26.1 %
Schistosoma mansoni biogenic amine receptor Histamine H1 receptor   488 aa 487 aa 25.5 %
Onchocerca volvulus RB1-inducible coiled-coil protein 1 homolog Histamine H1 receptor   488 aa 486 aa 26.5 %
Echinococcus granulosus biogenic amine 5HT receptor Histamine H1 receptor   488 aa 455 aa 25.5 %
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor Histamine H1 receptor   488 aa 488 aa 26.6 %
Echinococcus granulosus biogenic amine 5HT receptor Histamine H1 receptor   488 aa 484 aa 26.9 %
Echinococcus granulosus alpha 1A adrenergic receptor Histamine H1 receptor   488 aa 455 aa 19.1 %
Schistosoma japonicum Octopamine receptor, putative Histamine H1 receptor   488 aa 472 aa 25.8 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Histamine H1 receptor   488 aa 482 aa 25.1 %
Echinococcus multilocularis alpha 1A adrenergic receptor Histamine H1 receptor   488 aa 454 aa 19.4 %
Echinococcus multilocularis serotonin receptor Histamine H1 receptor   488 aa 450 aa 26.0 %
Schistosoma mansoni biogenic amine (dopamine) receptor Histamine H1 receptor   488 aa 471 aa 24.8 %
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) Histamine H1 receptor   488 aa 463 aa 26.6 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Histamine H1 receptor   488 aa 470 aa 26.0 %
Loa Loa (eye worm) TYRA-2 protein Histamine H1 receptor   488 aa 489 aa 23.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0051 0.0049
Onchocerca volvulus 0.0091 0.0144 0.0402
Brugia malayi Cytochrome P450 family protein 0.0072 0.0107 0.0237
Brugia malayi bHLH-PAS transcription factor 0.0154 0.0271 0.0608
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0056 0.0054
Echinococcus granulosus GPCR family 2 0.0105 0.0173 0.0171
Schistosoma mansoni hypothetical protein 0.0086 0.0136 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0009 0.002
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0142 0.0141
Trichomonas vaginalis glutaminase, putative 0.2227 0.4438 1
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Entamoeba histolytica Ran family GTPase 0.0022 0.0007 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0038 0.0067
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0119 0.0117
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0011 0.0021
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0031 0.0024 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0107 0.0237
Brugia malayi Cytochrome P450 family protein 0.0072 0.0107 0.0237
Brugia malayi Tubulin beta chain 0.044 0.0847 0.1905
Trypanosoma brucei epsilon tubulin 0.1007 0.1987 0.3663
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0106 0.0235
Echinococcus granulosus CREB binding protein 0.0033 0.0029 0.0027
Entamoeba histolytica hypothetical protein 0.0044 0.0051 0.0139
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0042 0.0041
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.002
Trichomonas vaginalis tubulin alpha chain, putative 0.0538 0.1044 0.2351
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Brugia malayi Tubulin beta chain 0.0538 0.1044 0.2349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.0062
Loa Loa (eye worm) TAR-binding protein 0.007 0.0104 0.0231
Schistosoma mansoni hypothetical protein 0.0086 0.0136 0.0135
Echinococcus multilocularis bloom syndrome protein 0.0069 0.01 0.0099
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Echinococcus granulosus Smad4 0.012 0.0204 0.0203
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0051 0.005
Trypanosoma brucei unspecified product 0.0055 0.0072 0.013
Brugia malayi RNA binding protein 0.007 0.0104 0.0231
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0071 0.0159
Brugia malayi RNA, U transporter 1 0.0086 0.0135 0.0302
Loa Loa (eye worm) hypothetical protein 0.0257 0.0478 0.1074
Loa Loa (eye worm) hypothetical protein 0.0044 0.0051 0.011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0404 0.091
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0087 0.0192
Trypanosoma cruzi alpha tubulin, putative 0.1342 0.2659 0.7547
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.004 0.0038
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.009 0.0142 0.04
Schistosoma mansoni hypothetical protein 0.0323 0.0612 0.0612
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0018 0.0037
Toxoplasma gondii aminopeptidase N protein 0.0326 0.0618 0.1752
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0157 0.0353
Toxoplasma gondii protease inhibitor PI2 0.0062 0.0087 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0078 0.0177
Entamoeba histolytica recQ family DNA helicase 0.0021 0.0004 0.0008
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0053 0.0051
Mycobacterium ulcerans 6-phosphofructokinase 0.022 0.0404 0.0907
Trypanosoma brucei tubulin gamma chain 0.1008 0.1988 0.3665
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.346 0.6917 0.6917
Brugia malayi Bromodomain containing protein 0.0093 0.0149 0.0332
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.0014 0.0028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0105 0.0173 0.0386
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0137 0.0137
Leishmania major hypothetical protein, conserved 0.0028 0.0018 0.0047
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0004 0.0008
Echinococcus granulosus expressed protein 0.0761 0.1492 0.1491
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Schistosoma mansoni multidrug resistance protein 0.0023 0.0009 0.0009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0072 0.02
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0072 0.016
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0004 0.0008
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.0071 0.0069
Schistosoma mansoni cell division control protein 48 aaa family protein 0.003 0.0022 0.0022
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0009 0.0007
Toxoplasma gondii target of rapamycin (TOR), putative 0.0072 0.0107 0.0299
Brugia malayi intermediate filament protein 0.0199 0.0363 0.0815
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0107 0.0299
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.0015
Trypanosoma brucei beta tubulin 0.1771 0.3523 0.6498
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0045 0.0044
Echinococcus multilocularis tubulin alpha chain 0.1342 0.2659 0.2658
Echinococcus granulosus jumonji domain containing 1A 0.0028 0.0018 0.0017
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus granulosus neuropeptide receptor A26 0.0986 0.1944 0.1943
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.007 0.0102 0.0101
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Brugia malayi Trypsin family protein 0.0092 0.0148 0.0329
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0067 0.0149
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0087 0.0242
Leishmania major epsilon tubulin, putative 0.1007 0.1987 0.5637
Schistosoma mansoni hypothetical protein 0.0105 0.0173 0.0172
Loa Loa (eye worm) glutathione reductase 0.0155 0.0274 0.0615
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0105 0.0173 0.0172
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0097 0.0157 0.0155
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Echinococcus granulosus Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.003 0.0022 0.002
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0623 0.1215 0.3446
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0072 0.02
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0097 0.0157 0.0349
Echinococcus multilocularis peroxisome assembly protein 26 0.1342 0.2659 0.2658
Loa Loa (eye worm) phosphofructokinase 0.022 0.0404 0.0907
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0293 0.0551 0.0549
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0189
Schistosoma mansoni thyroid hormone receptor 0.007 0.0102 0.0102
Schistosoma mansoni nuclear hormone receptor 0.007 0.0102 0.0102
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0011 0.0111
Echinococcus multilocularis CAAX prenyl protease 2 0.009 0.0142 0.0141
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0045 0.0097
Onchocerca volvulus 0.003 0.0023 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Trichomonas vaginalis ran, putative 0.0022 0.0007 0.0016
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0122 0.1397
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0224 0.0412 0.0412
Entamoeba histolytica tubulin alpha chain, putative 0.1342 0.2659 0.7547
Echinococcus multilocularis dna polymerase eta 0.0102 0.0167 0.0165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Trypanosoma brucei Valosin-containing protein 0.0028 0.0019 0.0032
Schistosoma mansoni alpha tubulin 0.1342 0.2659 0.2659
Echinococcus multilocularis phd:f box containing protein 0.0028 0.0018 0.0017
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0055 0.0072 0.084
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0331 0.0627 0.1409
Schistosoma mansoni lamin 0.0199 0.0363 0.0363
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Toxoplasma gondii alpha tubulin TUBA1 0.1342 0.2659 0.7547
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.003 0.008
Schistosoma mansoni smad 0.012 0.0204 0.0204
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0056 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.0014 0.0028
Echinococcus multilocularis tubulin beta 1 chain 0.1771 0.3523 0.3522
Loa Loa (eye worm) hypothetical protein 0.0094 0.0152 0.0339
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.0102 0.0101
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0056 0.0075 0.0835
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0082 0.431
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0003 0.0026
Echinococcus granulosus tubulin gamma 1 chain 0.1008 0.1988 0.1986
Echinococcus multilocularis lysine specific demethylase 6a 0.0028 0.0018 0.0017
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.003 0.0063
Loa Loa (eye worm) pax transcription factor protein 2 0.026 0.0485 0.1089
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0071 0.0197
Toxoplasma gondii aminopeptidase n, putative 0.0326 0.0618 0.1752
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Trypanosoma cruzi PAB1-binding protein , putative 0.0133 0.023 0.065
Schistosoma mansoni hypothetical protein 0.1772 0.3524 0.3523
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0055 0.0072 0.02
Plasmodium falciparum JmjC domain-containing protein, putative 0.0028 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0054 0.007 0.0155
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0022 0.0007 0.0006
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0657 0.1283 0.1282
Echinococcus granulosus Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0038 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0152
Trichomonas vaginalis tubulin epsilon chain, putative 0.1342 0.2659 0.5992
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.0071 0.0069
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0354 0.0674 0.7957
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Trichomonas vaginalis tubulin epsilon chain, putative 0.1342 0.2659 0.5992
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0041 0.0045 0.0043
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0042 0.009
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0009 0.0021
Onchocerca volvulus 0.0086 0.0135 0.0375
Trypanosoma brucei alpha tubulin 0.1342 0.2659 0.4905
Loa Loa (eye worm) steroid hormone receptor 0.007 0.0102 0.0227
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0011 0.0111
Brugia malayi nuclear receptor NHR-67 0.003 0.0023 0.0049
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.0404 0.0907
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0014 0.0153
Loa Loa (eye worm) hypothetical protein 0.0155 0.0275 0.0616
Brugia malayi regulator of G-protein signaling egl-10 0.0051 0.0065 0.0142
Brugia malayi beta-tubulin, identical 0.1771 0.3523 0.7937
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0035
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.007 0.0196
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0087 0.0192
Loa Loa (eye worm) hypothetical protein 0.0038 0.0038 0.0082
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0265 0.0496 0.0494
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.003 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0023 0.0023
Echinococcus granulosus lamin 0.0199 0.0363 0.0362
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0057 0.0078 0.0077
Loa Loa (eye worm) BEN-1 protein 0.1771 0.3523 0.7937
Loa Loa (eye worm) hypothetical protein 0.0046 0.0055 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Leishmania major DNA polymerase eta, putative 0.0102 0.0167 0.0469
Loa Loa (eye worm) hypothetical protein 0.0804 0.1578 0.3553
Loa Loa (eye worm) hypothetical protein 0.0165 0.0293 0.0658
Brugia malayi alpha-tubulin 0.1342 0.2659 0.599
Echinococcus granulosus tubulin alpha 3 chain 0.1342 0.2659 0.2658
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Schistosoma mansoni tubulin subunit gamma 0.1008 0.1988 0.1987
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0142 0.0317
Echinococcus multilocularis Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1771 0.3523 0.3522
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0051 0.005
Brugia malayi SPARC precursor 0.0062 0.0087 0.0192
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0014 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0023 0.0022
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0052
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0051 0.005
Plasmodium vivax glutathione reductase, putative 0.0155 0.0274 0.0775
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0017 0.0044
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0007 0.0005
Onchocerca volvulus 0.0054 0.0071 0.0191
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0014 0.0028
Schistosoma mansoni smad1 5 8 and 0.012 0.0204 0.0204
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0017 0.019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0023 0.0022
Brugia malayi Bromodomain containing protein 0.0046 0.0055 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0133 0.023 0.065
Loa Loa (eye worm) hypothetical protein 0.0078 0.0119 0.0265
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0054 0.007 0.0196
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0023 0.0049
Brugia malayi MH1 domain containing protein 0.0067 0.0096 0.0213
Plasmodium vivax thioredoxin reductase, putative 0.0155 0.0274 0.0775
Loa Loa (eye worm) hypothetical protein 0.0044 0.0051 0.011
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0007 0.0005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0056 0.0074 0.0073
Brugia malayi Steroid receptor seven-up type 2 0.007 0.0102 0.0227
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0071 0.0159
Echinococcus multilocularis JmjC domain containing protein 4 0.0028 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Loa Loa (eye worm) hypothetical protein 0.0241 0.0446 0.1001
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0135 0.0133
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Echinococcus multilocularis Niemann Pick C1 protein 0.0298 0.0561 0.056
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0056 0.0127
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0097 0.0157 0.044
Schistosoma mansoni eyes absent homolog 0.0078 0.0119 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.0062
Trypanosoma brucei unspecified product 0.0038 0.0038 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Loa Loa (eye worm) hypothetical protein 0.0105 0.0173 0.0386
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.007 0.0102 0.0282
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Brugia malayi hypothetical protein 0.0226 0.0416 0.0934
Echinococcus granulosus geminin 0.1256 0.2488 0.2486
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Echinococcus granulosus mothers against decapentaplegic 2 0.0054 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.009
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0073 0.0202
Echinococcus multilocularis Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Trypanosoma brucei beta tubulin 0.1771 0.3523 0.6498
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0011 0.0017
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0096 0.0156 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Schistosoma mansoni phd/f-box containing protein 0.0028 0.0018 0.0018
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0088 0.0245
Echinococcus multilocularis lipoxygenase domain containing protein 0.0165 0.0293 0.0292
Loa Loa (eye worm) hypothetical protein 0.0078 0.0119 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Plasmodium falciparum phd finger protein, putative 0.0033 0.003 0.008
Echinococcus multilocularis Tubulin beta 2C chain 0.1771 0.3523 0.3522
Echinococcus multilocularis thioredoxin glutathione reductase 0.0155 0.0274 0.0273
Loa Loa (eye worm) tubulin alpha 2 0.0902 0.1775 0.3997
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0185 0.0418
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0072 0.0071
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0137 0.0306
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0045 0.0097
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0014 0.0035
Brugia malayi SET domain containing protein 0.0022 0.0007 0.0012
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0014 0.0035
Echinococcus granulosus JmjC domain containing protein 4 0.0028 0.0018 0.0017
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0009 0.0021
Brugia malayi secreted modular calcium-binding protein 1 0.0062 0.0087 0.0192
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0097 0.0157 0.044
Brugia malayi nuclear receptor NHR-88 0.007 0.0102 0.0227
Brugia malayi hypothetical protein 0.0044 0.0051 0.011
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0062 0.0088 0.0245
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Trichomonas vaginalis tubulin alpha chain, putative 0.1771 0.3523 0.7938
Echinococcus granulosus tubulin epsilon chain 0.1007 0.1987 0.1985
Schistosoma mansoni hypothetical protein 0.0226 0.0417 0.0416
Entamoeba histolytica recQ family helicase, putative 0.0047 0.0056 0.0155
Schistosoma mansoni blooms syndrome DNA helicase 0.0048 0.0059 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.007 0.0102 0.0227
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0122 0.1432
Echinococcus multilocularis mothers against decapentaplegic 2 0.0054 0.007 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0075 0.0876
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.007 0.0815
Brugia malayi jmjC domain containing protein 0.0173 0.031 0.0696
Echinococcus multilocularis tubulin gamma 1 chain 0.1008 0.1988 0.1986
Echinococcus granulosus CREB binding protein 0.0133 0.023 0.0229
Trichomonas vaginalis tubulin gamma chain, putative 0.044 0.0847 0.1908
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0072 0.0196
Loa Loa (eye worm) hypothetical protein 0.0102 0.0167 0.0372
Loa Loa (eye worm) phosphatidylinositol 3 0.0097 0.0157 0.0349
Loa Loa (eye worm) tubulin beta-1 chain 0.1771 0.3523 0.7937
Echinococcus multilocularis CREB binding protein 0.0147 0.0258 0.0257
Mycobacterium ulcerans putative regulatory protein 0.0154 0.0271 0.0608
Loa Loa (eye worm) tubulin gamma chain 0.1008 0.1988 0.4476
Trypanosoma cruzi Valosin-containing protein, putative 0.0028 0.0019 0.0049
Brugia malayi isocitrate dehydrogenase 0.0033 0.003 0.0063
Trichomonas vaginalis helicase, putative 0.0035 0.0033 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.007 0.0102 0.0102
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.022 0.0404 0.4742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0077 0.0174
Echinococcus granulosus intermediate filament protein 0.0199 0.0363 0.0362
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0087 0.0242
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0046 0.0054 0.0097
Mycobacterium ulcerans bacterioferritin BfrA 0.0062 0.0087 0.0193
Loa Loa (eye worm) inositol-1 0.0062 0.0088 0.0195
Schistosoma mansoni jumonji domain containing protein 0.0028 0.0018 0.0018
Echinococcus granulosus tumor protein p63 0.2805 0.56 0.5599
Brugia malayi Nuclear hormone receptor family member nhr-41 0.007 0.0102 0.0227
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0009 0.0021
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Loa Loa (eye worm) tubulin alpha 2 0.0902 0.1775 0.3997
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0009 0.0007
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0062 0.0087 0.1012
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.003 0.0022 0.002
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0087 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.0102 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.001
Mycobacterium leprae Conserved hypothetical protein 0.0026 0.0014 0.0114
Plasmodium falciparum alpha tubulin 1 0.1342 0.2659 0.7547
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0054 0.007 0.0196
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0071 0.0197
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0003 0.0004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0012 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0033 0.0032
Toxoplasma gondii cell division protein CDC48CY 0.003 0.0022 0.0058
Echinococcus granulosus tubulin alpha 3 chain 0.1342 0.2659 0.2658
Onchocerca volvulus 0.0022 0.0007 0.0007
Brugia malayi Tubulin gamma chain 0.1008 0.1988 0.4476
Echinococcus multilocularis protein patched 0.0089 0.0142 0.0141
Trichomonas vaginalis taga, putative 0.0023 0.0009 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.0102 0.0101
Plasmodium falciparum tubulin epsilon chain, putative 0.1007 0.1987 0.5637
Plasmodium vivax ataxin-2 like protein, putative 0.0133 0.023 0.065
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0106 0.0296
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0002 0.0006
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0041 0.0045 0.0122
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0354 0.0674 0.7957
Schistosoma mansoni tubulin subunit alpha 0.1342 0.2659 0.2659
Toxoplasma gondii aminopeptidase N, putative 0.0326 0.0618 0.1752
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.007 0.0196
Schistosoma mansoni z-protein (S1r protein) 0.0051 0.0065 0.0064
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0007 0.0006
Plasmodium vivax SET domain protein, putative 0.0224 0.0412 0.1166
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0111 0.0185 0.0339
Brugia malayi 6-phosphofructokinase 0.022 0.0404 0.0908
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0293 0.0551 0.055
Brugia malayi Tubulin alpha chain 0.1342 0.2659 0.599
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0023 0.0022
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0341 0.0341
Echinococcus multilocularis tumor protein p63 0.2805 0.56 0.5599
Echinococcus granulosus muscleblind protein 0.0118 0.02 0.0199
Loa Loa (eye worm) tubulin alpha 2 0.0364 0.0694 0.156
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0404 0.091
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.007 0.0127
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0185 0.0522
Entamoeba histolytica hypothetical protein 0.0044 0.0051 0.0139
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.0014 0.0028
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0056 0.0153
Toxoplasma gondii LsmAD domain-containing protein 0.0133 0.023 0.065
Echinococcus multilocularis ferritin 0.0062 0.0087 0.0086
Trypanosoma cruzi epsilon tubulin, putative 0.1007 0.1987 0.5637
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1342 0.2659 0.5992
Brugia malayi Nuclear hormone receptor family member nhr-49 0.007 0.0102 0.0227
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0144 0.0324
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0054 0.007 0.0155
Echinococcus granulosus peregrin 0.0046 0.0055 0.0054
Schistosoma mansoni regulator of G protein signaling 0.0051 0.0065 0.0064
Toxoplasma gondii endonuclease IV APN 0.0079 0.0122 0.0342
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0022 0.0007 0.0012
Echinococcus multilocularis dna polymerase kappa 0.0055 0.0072 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.007 0.0102 0.0227
Schistosoma mansoni DNA helicase recq1 0.0041 0.0045 0.0044
Leishmania major ATP-dependent phosphofructokinase 0.022 0.0404 0.1142
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.022 0.0404 0.0403
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0007 0.0005
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0053 0.0051
Loa Loa (eye worm) hypothetical protein 0.0143 0.025 0.0559
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0062 0.0088 0.0245
Trichomonas vaginalis inositol monophosphatase, putative 0.0062 0.0088 0.0198
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0009 0.0007
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.001
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.0015
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0075 0.0166
Echinococcus granulosus importin subunit beta 1 0.003 0.0023 0.0022
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0144 0.0322
Trypanosoma brucei zeta tubulin, putative 0.0746 0.1462 0.2695
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0056 0.01
Brugia malayi MH1 domain containing protein 0.012 0.0204 0.0457
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.003 0.008
Onchocerca volvulus 0.0411 0.0788 0.225
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0012 0.0026
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0056 0.0153
Loa Loa (eye worm) CXXC zinc finger family protein 0.0154 0.0272 0.061
Brugia malayi tubulin alpha chain - mouse 0.1342 0.2659 0.599
Echinococcus multilocularis expressed conserved protein 0.0196 0.0356 0.0354
Schistosoma mansoni tubulin subunit epsilon 0.1007 0.1987 0.1986
Loa Loa (eye worm) hypothetical protein 0.0046 0.0056 0.0122
Loa Loa (eye worm) RNA binding protein 0.007 0.0104 0.0231
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.0404 0.0742
Echinococcus granulosus bloom syndrome protein 0.0069 0.01 0.0099
Loa Loa (eye worm) tubulin beta chain 0.044 0.0847 0.1905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0068 0.0149
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0088 0.0086
Echinococcus multilocularis tubulin subunit beta 0.1771 0.3523 0.3522
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0009 0.0021
Leishmania major importin beta-1 subunit, putative 0.0025 0.0012 0.0029
Schistosoma mansoni hypothetical protein 0.006 0.0083 0.0082
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0404 0.1142
Brugia malayi hypothetical protein 0.0086 0.0135 0.0302
Loa Loa (eye worm) MBCTL1 0.0062 0.0088 0.0194
Echinococcus multilocularis smad 0.012 0.0204 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0014 0.0153
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0341 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0038 0.0067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0088 0.0245
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0056 0.0054
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0009 0.002
Schistosoma mansoni inositol monophosphatase 0.0062 0.0088 0.0088
Echinococcus granulosus Niemann Pick C1 protein 0.0208 0.0381 0.038
Onchocerca volvulus 0.1753 0.3485 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0088 0.0245
Trypanosoma brucei CAAX amino terminal protease, putative 0.009 0.0142 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0111 0.0185 0.0521
Leishmania major beta tubulin 0.1771 0.3523 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0012 0.0029
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0053 0.0115
Loa Loa (eye worm) tubulin alpha chain 0.1342 0.2659 0.599
Trypanosoma brucei aminopeptidase, putative 0.0022 0.0007 0.001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0045 0.0122
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0226 0.0416 0.0415
Schistosoma mansoni intermediate filament proteins 0.0199 0.0363 0.0363
Brugia malayi hypothetical protein 0.0039 0.0042 0.009
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.004 0.0042 0.0091
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0241 0.0446 0.0444
Echinococcus granulosus tubulin beta 1 chain 0.1771 0.3523 0.3522
Echinococcus multilocularis dnaJ subfamily B 0.1772 0.3524 0.3523
Loa Loa (eye worm) beta-tubulin 0.1771 0.3523 0.7937
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0115 0.0194 0.0192
Echinococcus multilocularis Niemann Pick C1 protein 0.0208 0.0381 0.038
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0051 0.0049
Brugia malayi hypothetical protein 0.0387 0.074 0.1665
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0033 0.0073
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0478 0.0477
Giardia lamblia Beta tubulin 0.1771 0.3523 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0106 0.0296
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0055 0.0072 0.0072
Loa Loa (eye worm) raf kinase 0.0045 0.0054 0.0117
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0082 0.0227
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Schistosoma mansoni cytochrome P450 0.0026 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0014 0.0153
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0009 0.0007
Schistosoma mansoni importin beta-1 0.003 0.0023 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0056 0.0055
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.0014 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.0102 0.0227
Schistosoma mansoni hypothetical protein 0.0337 0.0639 0.0639
Trypanosoma brucei trypanothione reductase 0.0155 0.0274 0.0503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0077 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0017 0.0044
Schistosoma mansoni alpha tubulin 0.1342 0.2659 0.2659
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0014 0.0153
Echinococcus granulosus ecdysone induced protein 78C 0.007 0.0102 0.0101
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0023 0.0022
Plasmodium falciparum thioredoxin reductase 0.0054 0.007 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Entamoeba histolytica hypothetical protein 0.002 0.0003 0.0003
Plasmodium falciparum tubulin gamma chain 0.1008 0.1988 0.564
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0097 0.0157 0.044
Echinococcus granulosus mothers against decapentaplegic 6 0.0054 0.007 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0056 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0014 0.0153
Schistosoma mansoni bromodomain containing protein 0.0024 0.001 0.0009
Schistosoma mansoni tar DNA-binding protein 0.007 0.0104 0.0104
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0003 0.0005
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0016
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0028 0.0019 0.0049
Chlamydia trachomatis endonuclease IV 0.0079 0.0122 0.6536
Echinococcus granulosus expressed conserved protein 0.0196 0.0356 0.0354
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0051 0.0049
Toxoplasma gondii thioredoxin reductase 0.0155 0.0274 0.0775
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0137 0.0306
Chlamydia trachomatis cytosol aminopeptidase 0.0111 0.0185 1
Brugia malayi nuclear receptor RXR 0.0039 0.0042 0.009
Echinococcus multilocularis lamin 0.0199 0.0363 0.0362
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0335 0.0636 0.0635
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0144 0.0142
Echinococcus granulosus Tubulin beta 2C chain 0.1771 0.3523 0.3522
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0014 0.0153
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1771 0.3523 0.3522
Trichomonas vaginalis tubulin alpha chain, putative 0.0538 0.1044 0.2351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0014 0.0033
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0023 0.004
Echinococcus multilocularis Tubulin beta 2C chain 0.1771 0.3523 0.3522
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0011 0.0027
Treponema pallidum ATP-dependent DNA helicase 0.0021 0.0004 0.0033
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0072 0.0071
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0118 0.033
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0902 0.1775 0.3999
Plasmodium falciparum ataxin-2 like protein, putative 0.0133 0.023 0.065
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0054 0.0071 0.0159
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0208 0.0381 0.1078
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0082 0.0227
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.007 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Trichomonas vaginalis tubulin beta-1 chain, putative 0.044 0.0847 0.1908
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0056 0.0125
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0072 0.084
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.022 0.0404 0.4763
Mycobacterium ulcerans leucyl aminopeptidase 0.0111 0.0185 0.0414
Schistosoma mansoni Smad4 0.012 0.0204 0.0204
Schistosoma mansoni jun-related protein 0.0216 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0272
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0155 0.0274 0.3232
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0212 0.0389 0.0388
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0185 0.0522
Echinococcus multilocularis GPCR, family 2 0.0105 0.0173 0.0171
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0135 0.0135
Echinococcus granulosus tubulin subunit TubB 0.1342 0.2659 0.2658
Echinococcus granulosus tubulin alpha chain 0.1342 0.2659 0.2658
Echinococcus granulosus RUN 0.0165 0.0293 0.0292
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0003
Mycobacterium leprae putative cytochrome p450 0.0026 0.0014 0.0114
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0569 0.1612
Leishmania major beta tubulin 0.1771 0.3523 1
Giardia lamblia Delta tubulin 0.044 0.0847 0.24
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Giardia lamblia PHD finger protein 15 0.0033 0.003 0.008
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0027 0.0048
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0011 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0157 0.0353
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.0404 0.1142
Schistosoma mansoni tubulin subunit delta 0.044 0.0847 0.0846
Leishmania major beta tubulin 0.1771 0.3523 1
Schistosoma mansoni bromodomain containing protein 0.0081 0.0126 0.0126
Entamoeba histolytica tubulin alpha-1 chain 0.1342 0.2659 0.7547
Trichomonas vaginalis tubulin epsilon chain, putative 0.1771 0.3523 0.7938
Echinococcus multilocularis tubulin alpha 1C chain 0.1342 0.2659 0.2658
Mycobacterium ulcerans epimerase 0.0021 0.0004 0.0006
Toxoplasma gondii beta-1 tubulin, putative 0.1771 0.3523 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0053 0.0115
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0046 0.0056 0.0054
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0051 0.011
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0082 0.0227
Trichomonas vaginalis DNA helicase recq1, putative 0.0069 0.01 0.0226
Echinococcus multilocularis CREB binding protein 0.0033 0.0029 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.003 0.008
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0054 0.007 0.019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0056 0.0075 0.0872
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.003 0.0338
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.003 0.0029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.003 0.0028
Schistosoma mansoni follistatin 0.0062 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0044 0.0051 0.011
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0063 0.0089 0.0248
Schistosoma mansoni hypothetical protein 0.0105 0.0173 0.0172
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0023 0.0054
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0065 0.0142
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.0612 0.1376
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0144 0.0402
Loa Loa (eye worm) BEN-1 protein 0.1771 0.3523 0.7937
Leishmania major beta tubulin 0.1771 0.3523 1
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0072 0.0072
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0075 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.0102 0.0101
Loa Loa (eye worm) doublecortin family protein 0.0165 0.0293 0.0658
Echinococcus multilocularis hypothetical protein 0.1342 0.2659 0.2658
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0009 0.0007
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0394 0.0753 0.8896
Echinococcus granulosus FTZ F1 alpha 0.007 0.0102 0.0101
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0023 0.0054
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Mycobacterium tuberculosis Cell division protein FtsZ 0.044 0.0847 1
Echinococcus granulosus lamin dm0 0.0199 0.0363 0.0362
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0027 0.0074
Schistosoma mansoni CREB-binding protein 2 0.021 0.0385 0.0385
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.003 0.008
Trypanosoma brucei PAB1-binding protein , putative 0.0133 0.023 0.0422
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0106 0.0296
Brugia malayi ImpB/MucB/SamB family protein 0.0102 0.0167 0.0372
Brugia malayi hypothetical protein 0.0165 0.0293 0.0658
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0028 0.0018 0.0047
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0017 0.0035
Schistosoma mansoni hypothetical protein 0.0216 0.0396 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Schistosoma mansoni TGF-beta signal transducer Smad2 0.012 0.0204 0.0204
Echinococcus multilocularis musashi 0.0199 0.0363 0.0362
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0173 0.031 0.0309
Giardia lamblia Gamma tubulin 0.1008 0.1988 0.564
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0017 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0117 0.0263
Echinococcus multilocularis thyroid hormone receptor alpha 0.007 0.0102 0.0101
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Onchocerca volvulus 0.0199 0.0363 0.1031
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.003 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0194 0.0193
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0054 0.007 0.0196
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.0102 0.0227
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0072 0.02
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0185 0.0522
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0033 0.0073
Echinococcus multilocularis tubulin alpha chain 0.1342 0.2659 0.2658
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0051 0.0049
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0054 0.007 0.0196
Echinococcus granulosus endonuclease exonuclease phosphatase 0.022 0.0404 0.0403
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Giardia lamblia Fructose-bisphosphate aldolase 0.0302 0.0569 0.1612
Mycobacterium ulcerans bacterioferritin BfrB 0.0062 0.0087 0.0193
Schistosoma mansoni SET domain protein 0.0022 0.0007 0.0007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0056 0.0153
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0102 0.0227
Trichomonas vaginalis DNA helicase recq, putative 0.0069 0.01 0.0226
Loa Loa (eye worm) hypothetical protein 0.0087 0.0137 0.0306
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0009 0.0007
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0082 0.0227
Loa Loa (eye worm) hypothetical protein 0.0067 0.0096 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Onchocerca volvulus 0.0199 0.0363 0.1031
Trypanosoma brucei unspecified product 0.0038 0.0038 0.0067
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0106 0.0104
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0122 0.0121
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0056 0.0155
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0054 0.007 0.0069
Schistosoma mansoni myst-related protein 0.002 0.0003 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0014 0.0153
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0105 0.0173 0.0171
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0105 0.0173 0.0171
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0027 0.0048
Schistosoma mansoni cpg binding protein 0.0154 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0014 0.0153
Trypanosoma brucei DNA polymerase eta, putative 0.0102 0.0167 0.0305
Brugia malayi Tubulin alpha chain 0.044 0.0847 0.1905
Loa Loa (eye worm) tubulin beta-4 chain 0.1771 0.3523 0.7937
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0028 0.0018 0.0047
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0009 0.0007
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.009 0.0142 0.0321
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0142 0.0141
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.007 0.0102 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0404 0.1142
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0087 0.0242
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0045 0.0044
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0088 0.0086
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0064 0.0091 0.0254
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0017 0.019
Onchocerca volvulus 0.0154 0.0271 0.0766
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0224 0.0412 0.0411
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0022 0.0007 0.0012
Leishmania major delta tubulin, putative 0.0623 0.1215 0.3446
Echinococcus multilocularis mothers against decapentaplegic 5 0.012 0.0204 0.0203
Echinococcus multilocularis agrin 0.0062 0.0087 0.0085
Leishmania major GTP-binding protein, putative 0.0022 0.0007 0.0016
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0051 0.005
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0902 0.1775 0.3997
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0185 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0071 0.0159
Echinococcus multilocularis expressed protein 0.0062 0.0087 0.0085
Brugia malayi F/Y-rich N-terminus family protein 0.0068 0.0099 0.022
Loa Loa (eye worm) hypothetical protein 0.0093 0.0148 0.0331
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0075 0.0074
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0204 0.0457
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Echinococcus granulosus TGF beta signal transducer SmadC 0.012 0.0204 0.0203
Loa Loa (eye worm) hypothetical protein 0.0074 0.0112 0.0248
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0082 0.0184
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Trichomonas vaginalis ferritin, putative 0.0062 0.0087 0.0196
Echinococcus granulosus dna polymerase kappa 0.0055 0.0072 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0017 0.0035
Brugia malayi Nuclear hormone receptor E75 0.003 0.0023 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0056 0.0125
Loa Loa (eye worm) hypothetical protein 0.0387 0.074 0.1665
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.0014 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0194 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0006
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.0014 0.0028
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0043 0.0049 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0073 0.0202
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0051 0.011
Entamoeba histolytica hypothetical protein 0.0226 0.0416 0.1177
Loa Loa (eye worm) bromodomain containing protein 0.0028 0.0018 0.0038
Leishmania major protein kinase, putative 0.0058 0.0079 0.022
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0096 0.0156 0.0154
Schistosoma mansoni jumonji domain containing protein 0.0151 0.0265 0.0265
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0009 0.0093
Entamoeba histolytica hypothetical protein 0.0226 0.0416 0.1177
Brugia malayi hypothetical protein 0.0091 0.0144 0.0322
Brugia malayi PXA domain containing protein 0.0044 0.0051 0.011
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0051 0.0049
Toxoplasma gondii leucyl aminopeptidase LAP 0.0111 0.0185 0.0521
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0194
Onchocerca volvulus 0.0538 0.1044 0.2985
Treponema pallidum bacterioferrin (TpF1) 0.0062 0.0087 0.1012
Brugia malayi CAAX amino terminal protease family protein 0.009 0.0142 0.0318
Leishmania major beta tubulin 0.1771 0.3523 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.02 0.0447
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.0014 0.0028
Schistosoma mansoni inositol monophosphatase 0.0062 0.0088 0.0088
Brugia malayi MH2 domain containing protein 0.012 0.0204 0.0457
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.007 0.0102 0.0101
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0199 0.0363 0.0815
Brugia malayi ecdysteroid receptor 0.007 0.0102 0.0227
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0053 0.0115
Onchocerca volvulus 0.0055 0.0072 0.0196
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0007 0.0016
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0104 0.0231
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0055 0.0072 0.0071
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0045 0.0054 0.0052
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0075 0.0074
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0007 0.0005
Trichomonas vaginalis tubulin gamma chain, putative 0.1007 0.1987 0.4476
Loa Loa (eye worm) hypothetical protein 0.0696 0.1362 0.3067
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.003 0.008
Onchocerca volvulus 0.0027 0.0017 0.0036
Schistosoma mansoni polycystin 1-related 0.0165 0.0293 0.0293
Schistosoma mansoni multidrug resistance protein 0.0023 0.0009 0.0009
Brugia malayi glutathione reductase 0.0155 0.0274 0.0615
Schistosoma mansoni aryl hydrocarbon receptor 0.0208 0.038 0.0379
Brugia malayi nuclear hormone receptor 0.007 0.0102 0.0227
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0027 0.0027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.007 0.0815
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0017 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0111 0.0185 0.2171
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0212 0.0388 0.0387
Loa Loa (eye worm) tubulin beta chain 0.1771 0.3523 0.7937
Entamoeba histolytica tubulin family protein 0.1771 0.3523 1
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0122 0.0272
Brugia malayi PHD-finger family protein 0.0022 0.0006 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Echinococcus granulosus tubulin subunit beta 0.1771 0.3523 0.3522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0259 0.058
Loa Loa (eye worm) DR-78 0.003 0.0023 0.0049
Brugia malayi Tubulin alpha-2 chain 0.1342 0.2659 0.599
Loa Loa (eye worm) hypothetical protein 0.011 0.0183 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0052
Treponema pallidum fructose-bisphosphate aldolase 0.0302 0.0569 0.6716
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0088 0.0199
Echinococcus granulosus tubulin alpha 1C chain 0.1342 0.2659 0.2658
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.0102 0.0227
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.0014 0.0028
Loa Loa (eye worm) MH1 domain-containing protein 0.0054 0.007 0.0155
Schistosoma mansoni cpg binding protein 0.0165 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.0071 0.0156
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0027 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0014 0.0153
Plasmodium vivax SET domain containing protein 0.0024 0.0011 0.0028
Toxoplasma gondii aldehyde dehydrogenase 0.0188 0.0341 0.0964
Trypanosoma brucei RNA helicase, putative 0.2715 0.542 1
Schistosoma mansoni zinc finger protein 0.003 0.0023 0.0023
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.009 0.0142 0.0142
Loa Loa (eye worm) MH1 domain-containing protein 0.012 0.0204 0.0457
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0106 0.0104
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0063
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0054 0.0071 0.3715
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0054 0.0071 0.0069
Leishmania major gamma-tubulin 0.1008 0.1988 0.564
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.007 0.0127
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0014 0.0028
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0009 0.0007
Echinococcus granulosus snurportin 1 0.0323 0.0612 0.061
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.007 0.0102 0.0101
Brugia malayi Cytochrome P450 family protein 0.0043 0.0048 0.0105
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.001
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0009 0.0021
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0073 0.0202
Trypanosoma brucei protein kinase, putative 0.0111 0.0185 0.0339
Echinococcus multilocularis lipoxygenase domain containing protein 0.0165 0.0293 0.0292
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0137 0.0136
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0142 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0142 0.032
Echinococcus multilocularis transfer RNA-Lys 0.0154 0.0271 0.027
Echinococcus granulosus inositol monophosphatase 1 0.0062 0.0088 0.0086
Echinococcus granulosus cpg binding protein 0.0165 0.0293 0.0292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0152
Onchocerca volvulus 0.026 0.0485 0.138
Schistosoma mansoni organic anion transporter 0.0091 0.0144 0.0144
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0014 0.0153
Schistosoma mansoni smdr2 0.0023 0.0009 0.0009
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0023 0.0022
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0003 0.0005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0106 0.0296
Schistosoma mansoni hypothetical protein 0.0226 0.0416 0.0416
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0266 0.0496 0.0495
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0082 0.0227
Onchocerca volvulus Huntingtin homolog 0.0387 0.074 0.2114
Echinococcus granulosus peroxisome assembly protein 26 0.1342 0.2659 0.2658
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0054 0.0053
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0062 0.0087 0.1017
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0106 0.0105
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0394 0.0753 0.8896
Trichomonas vaginalis adenylate cyclase, putative 0.0054 0.0071 0.0159
Brugia malayi Importin beta-1 subunit 0.003 0.0023 0.0049
Toxoplasma gondii transporter, major facilitator family protein 0.0091 0.0144 0.0406
Leishmania major beta tubulin 0.1771 0.3523 1
Mycobacterium tuberculosis Probable reductase 0.0354 0.0674 0.7957
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0017 0.0044
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0071 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0051 0.011
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.044 0.0847 1
Trypanosoma cruzi trypanothione reductase, putative 0.0155 0.0274 0.0775
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0017 0.0151
Schistosoma mansoni loxhd1 0.0165 0.0293 0.0293
Schistosoma mansoni Tr4/Tr2 (homologue) 0.007 0.0102 0.0102
Echinococcus multilocularis beta tubulin 0.1771 0.3523 0.3522
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.0015
Schistosoma mansoni hypothetical protein 0.0276 0.0517 0.0517
Schistosoma mansoni ferritin 0.0062 0.0087 0.0087
Brugia malayi PAS domain containing protein 0.0208 0.038 0.0852
Echinococcus multilocularis tubulin alpha 1C chain 0.1342 0.2659 0.2658
Leishmania major trypanothione reductase 0.0155 0.0274 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0117 0.0263
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0009 0.0021
Trypanosoma cruzi tubulin gamma chain 0.1008 0.1988 0.564
Entamoeba histolytica hypothetical protein 0.0226 0.0416 0.1177
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Brugia malayi Bromodomain containing protein 0.0048 0.0059 0.013
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0226 0.0416 0.0415
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0062 0.0088 0.0198
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0135 0.0301
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0042 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0107 0.0237
Brugia malayi Inositol-1 0.0062 0.0088 0.0195
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0072 0.0107 0.0237
Echinococcus granulosus Solute carrier organic anion transporter family 0.0091 0.0144 0.0143
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0023 0.004
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Brugia malayi Bloom's syndrome protein homolog 0.0069 0.01 0.0223
Trypanosoma brucei epsilon tubulin 0.0978 0.1928 0.3555
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0144 0.0324
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.009 0.0142 0.04
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.003 0.0028
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0072 0.013
Echinococcus multilocularis tar DNA binding protein 0.007 0.0104 0.0103
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0054 0.007 0.0069
Brugia malayi hypothetical protein 0.003 0.0023 0.0049
Trypanosoma cruzi zeta tubulin, putative 0.0746 0.1462 0.4148
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0014
Trichomonas vaginalis abcb9, putative 0.0023 0.0009 0.002
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0008 0.0007
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0054 0.007 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.007 0.0102 0.0227
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0144 0.0402
Loa Loa (eye worm) alpha-tubulin 0.1342 0.2659 0.599
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0023 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0404 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0088 0.0086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Echinococcus multilocularis lysine specific demethylase 5A 0.0104 0.0171 0.017
Brugia malayi hypothetical protein 0.0133 0.023 0.0516
Toxoplasma gondii tubulin, putative 0.0029 0.0021 0.0055
Echinococcus multilocularis raf serine:threonine protein kinase 0.0045 0.0054 0.0052
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Echinococcus granulosus beta tubulin 0.1771 0.3523 0.3522
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0056 0.0054
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0023 0.0022
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.0015
Echinococcus multilocularis protein dispatched 1 0.0102 0.0168 0.0166
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.0404 0.0907
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.003 0.0063
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0054 0.0071 0.0159
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0265 0.0496 0.0494
Schistosoma mansoni apoferritin-2 0.0062 0.0087 0.0087
Brugia malayi jmjC domain containing protein 0.0028 0.0018 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0117 0.0263
Schistosoma mansoni transcription factor LCR-F1 0.0226 0.0416 0.0416
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0188 0.0341 0.034
Echinococcus granulosus tubulin delta chain 0.044 0.0847 0.0845
Mycobacterium ulcerans hypothetical protein 0.0027 0.0017 0.0035
Schistosoma mansoni rab6-interacting 0.0165 0.0293 0.0293
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0032 0.0026 0.0055
Schistosoma mansoni hypothetical protein 0.002 0.0003 0.0003
Trypanosoma brucei alpha tubulin 0.1342 0.2659 0.4905
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0071 0.0159
Schistosoma mansoni zinc finger protein 0.0039 0.004 0.0039
Brugia malayi cytosol aminopeptidase 0.0022 0.0007 0.0012
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0009 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0354 0.0674 0.7957
Entamoeba histolytica cdc48-like protein, putative 0.0028 0.0019 0.0049
Schistosoma mansoni lipoxygenase 0.0361 0.0687 0.0687
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0354 0.0674 0.7957
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0194 0.0193
Schistosoma mansoni smad 0.0054 0.007 0.007
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0185 0.0418
Plasmodium falciparum alpha tubulin 2 0.1342 0.2659 0.7547
Brugia malayi mbt repeat family protein 0.0055 0.0072 0.016
Schistosoma mansoni survival motor neuron protein 0.0052 0.0068 0.0067
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.004 0.0038
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0023 0.0049
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus granulosus phd:f box containing protein 0.0028 0.0018 0.0017
Brugia malayi acetyltransferase, GNAT family protein 0.0293 0.0551 0.1238
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0087 0.0242
Leishmania major beta tubulin 0.1771 0.3523 1
Trypanosoma cruzi tubulin delta chain 0.0623 0.1215 0.3446
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0097 0.0157 0.0156
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0082 0.0227
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0046 0.0056 0.0054
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0028 0.0019 0.0049
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.002 0.0003 0.0003
Entamoeba histolytica deoxycytidyl transferase, putative 0.0055 0.0072 0.02
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0137 0.0136
Toxoplasma gondii alpha-tubulin I, putative 0.1342 0.2659 0.7547
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0051 0.005
Loa Loa (eye worm) MH2 domain-containing protein 0.0054 0.007 0.0155
Echinococcus multilocularis Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Schistosoma mansoni hypothetical protein 0.0086 0.0136 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.0102 0.0227
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.022 0.0404 0.4759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0078 0.0177
Echinococcus multilocularis ecdysone induced protein 78C 0.007 0.0102 0.0101
Leishmania major p-glycoprotein 0.0023 0.0009 0.0021
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0011 0.0078
Loa Loa (eye worm) cytochrome P450 0.0026 0.0014 0.0028
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0087 0.0192
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0054 0.007 0.0127
Loa Loa (eye worm) hypothetical protein 0.0055 0.0072 0.016
Loa Loa (eye worm) tubulin alpha chain 0.1342 0.2659 0.599
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.007 0.0196
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0259 0.3021
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0185 0.0185
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0188 0.0341 0.4022
Loa Loa (eye worm) hypothetical protein 0.0226 0.0417 0.0936
Loa Loa (eye worm) hypothetical protein 0.0387 0.074 0.1665
Echinococcus multilocularis Smad4 0.012 0.0204 0.0203
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0017 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.003 0.0052
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0097 0.0157 0.044
Loa Loa (eye worm) hypothetical protein 0.0902 0.1775 0.3997
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0111 0.0185 0.2176
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0072 0.02
Schistosoma mansoni hypothetical protein 0.1256 0.2488 0.2487
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0004
Echinococcus granulosus fetal alzheimer antigen falz 0.0031 0.0024 0.0023
Echinococcus granulosus histone acetyltransferase KAT2B 0.0279 0.0523 0.0521
Trypanosoma cruzi tubulin delta chain 0.0623 0.1215 0.3446
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0023 0.0022
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0054 0.007 0.0196
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0004 0.0006
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Echinococcus granulosus smad 0.012 0.0204 0.0203
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.0014 0.0028
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0538 0.1044 0.2351
Brugia malayi ABC transporter family protein 0.0023 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Brugia malayi cytoplasmic intermediate filament protein 0.0107 0.0177 0.0396
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0009 0.0021
Trichomonas vaginalis tubulin alpha chain, putative 0.0538 0.1044 0.2351
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Echinococcus granulosus neuropeptide s receptor 0.0986 0.1944 0.1943
Trypanosoma brucei beta tubulin 0.0978 0.1928 0.3555
Trypanosoma cruzi DNA polymerase eta, putative 0.0102 0.0167 0.0469
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0077 0.0117 0.0213
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0087 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0341 0.0765
Schistosoma mansoni 6-phosphofructokinase 0.022 0.0404 0.0403
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0008 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0241 0.0446 0.0446
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0148 0.0147
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.003 0.0029
Loa Loa (eye worm) thioredoxin reductase 0.0155 0.0274 0.0615
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0394 0.0753 0.8892
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0062 0.0088 0.0195
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0106 0.0192
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0009 0.0021
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0173 0.031 0.0309
Trichomonas vaginalis DNA polymerase eta, putative 0.0055 0.0072 0.0162
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0072 0.0072
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0007 0.0015
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0051 0.0049
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0051 0.005
Plasmodium falciparum tubulin beta chain 0.1771 0.3523 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0185 0.0339
Loa Loa (eye worm) hypothetical protein 0.0492 0.095 0.2139
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0009 0.0017
Trypanosoma brucei alpha tubulin, putative 0.0538 0.1044 0.1923
Brugia malayi Nuclear hormone receptor family member nhr-3 0.007 0.0102 0.0227
Echinococcus multilocularis tubulin subunit TubB 0.1342 0.2659 0.2658
Entamoeba histolytica recQ family helicase, putative 0.002 0.0003 0.0003
Schistosoma mansoni Smad4 0.0054 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Brugia malayi Pre-SET motif family protein 0.154 0.3058 0.689
Loa Loa (eye worm) hypothetical protein 0.0133 0.023 0.0516
Brugia malayi prostaglandin transporter 0.0091 0.0144 0.0322
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0082 0.0227
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0082 0.0227
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0106 0.0235
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0004 0.0008
Toxoplasma gondii beta tubulin 0.1771 0.3523 1
Mycobacterium leprae Possible regulatory protein 0.0054 0.0071 0.0789
Plasmodium falciparum glutathione reductase 0.0054 0.007 0.0196
Loa Loa (eye worm) hypoxia-induced factor 1 0.0642 0.1254 0.2822
Trypanosoma cruzi epsilon tubulin, putative 0.1007 0.1987 0.5637
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0054 0.007 0.0821
Echinococcus multilocularis expressed protein 0.0062 0.0087 0.0086
Giardia lamblia Sgs1 DNA helicase, putative 0.0041 0.0045 0.0122
Mycobacterium tuberculosis Probable dehydrogenase 0.0354 0.0674 0.7957
Plasmodium vivax hypothetical protein, conserved 0.0033 0.003 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0148 0.0147
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Brugia malayi hypothetical protein 0.0044 0.0051 0.011
Schistosoma mansoni organic anion transporter 0.0091 0.0144 0.0144
Brugia malayi PHD-finger family protein 0.0033 0.003 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0017 0.0035
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Leishmania major cytochrome p450-like protein 0.0072 0.0107 0.0299
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0054 0.007 0.0155
Loa Loa (eye worm) tubulin beta-2A chain 0.1771 0.3523 0.7937
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0978 0.1928 0.5471
Brugia malayi steroid hormone receptor 0.007 0.0102 0.0227
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0023 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0354 0.0674 0.7949
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.007 0.0102 0.0101
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0122 0.0342
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0144 0.0404
Schistosoma mansoni lipoxygenase 0.0657 0.1283 0.1283
Schistosoma mansoni tar DNA-binding protein 0.007 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0011 0.0422
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0003
Giardia lamblia Alpha-tubulin 0.1342 0.2659 0.7547
Echinococcus granulosus tubulin beta 4A class IVa 0.1771 0.3523 0.3522
Schistosoma mansoni leucine aminopeptidase 0.0022 0.0007 0.0006
Echinococcus multilocularis CREB binding protein 0.0033 0.0029 0.0027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0017 0.0151
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0185 0.0522
Onchocerca volvulus 0.0086 0.0135 0.0377
Loa Loa (eye worm) hypothetical protein 0.0086 0.0135 0.0301
Plasmodium falciparum glutathione reductase 0.0155 0.0274 0.0775
Echinococcus multilocularis tubulin alpha chain 0.1342 0.2659 0.2658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0117 0.0263
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0111 0.0185 0.0521
Echinococcus granulosus Polycystic kidney disease protein 0.0165 0.0293 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0014 0.0153
Echinococcus granulosus retinoic acid receptor rxr beta a 0.007 0.0102 0.0101
Plasmodium vivax tubulin beta chain, putative 0.1771 0.3523 1
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.009 0.0142 0.0318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.0062
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0111 0.0185 0.0521
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0007 0.0016
Echinococcus granulosus single minded 2 0.0154 0.0271 0.027
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0051 0.011
Echinococcus granulosus tubulin alpha chain 0.1342 0.2659 0.2658
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0011 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0075 0.0166
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0259 0.3048
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0056 0.0054
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0104 0.0231
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0082 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Brugia malayi Cell division protein ftsZ 0.044 0.0847 0.1905
Trypanosoma cruzi target of rapamycin kinase 3 0.0077 0.0117 0.0328
Echinococcus multilocularis expressed protein 0.0761 0.1492 0.1491
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0144 0.0322
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Loa Loa (eye worm) hypothetical protein 0.0208 0.0381 0.0856
Echinococcus multilocularis neuropeptide receptor A26 0.0986 0.1944 0.1943
Trypanosoma brucei cytochrome P450, putative 0.0072 0.0107 0.0194
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0017 0.0035
Plasmodium falciparum M17 leucyl aminopeptidase 0.0111 0.0185 0.0521
Plasmodium vivax tubulin gamma chain, putative 0.1008 0.1988 0.564
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0151
Giardia lamblia Beta tubulin 0.1771 0.3523 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0128 0.0289
Plasmodium vivax tubulin alpha chain, putative 0.1342 0.2659 0.7547
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0224 0.0412 0.1166
Trypanosoma brucei tubulin delta chain 0.0623 0.1215 0.2239
Trichomonas vaginalis spermatogenesis associated factor, putative 0.003 0.0022 0.005
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0122 0.0342
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.007 0.0102 0.0102
Loa Loa (eye worm) histone methyltransferase 0.0056 0.0074 0.0164
Onchocerca volvulus 0.0062 0.0087 0.0236
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0023 0.0023
Trichomonas vaginalis tubulin beta chain, putative 0.1771 0.3523 0.7938
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0404 0.091
Echinococcus multilocularis follistatin 0.0062 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0014 0.0153
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0011 0.0117
Echinococcus granulosus tubulin alpha chain 0.1342 0.2659 0.2658
Loa Loa (eye worm) nuclear factor I 0.0067 0.0096 0.0213
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0023 0.0022
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0041 0.0045 0.0043
Schistosoma mansoni multidrug resistance protein 0.0023 0.0009 0.0009
Onchocerca volvulus 0.0165 0.0293 0.083
Leishmania major beta tubulin 0.1771 0.3523 1
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0009 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0023 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0052
Plasmodium vivax importin-beta 2, putative 0.003 0.0023 0.0062
Mycobacterium leprae cell division protein FtsZ 0.044 0.0847 1
Brugia malayi Latrophilin receptor protein 2 0.0105 0.0173 0.0386
Onchocerca volvulus 0.007 0.0102 0.0282
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0056 0.0054
Trichomonas vaginalis set domain proteins, putative 0.1753 0.3485 0.7853
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.003 0.008
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0326 0.0618 0.1752
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0014 0.0153
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0185 0.0184
Brugia malayi jmjC domain containing protein 0.0028 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0017
Schistosoma mansoni smad1 5 8 and 0.012 0.0204 0.0204
Echinococcus granulosus agrin 0.0062 0.0087 0.0085
Echinococcus multilocularis cpg binding protein 0.0165 0.0293 0.0292
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0119 0.0117
Schistosoma mansoni phosphatidylserine receptor 0.0028 0.0018 0.0018
Trichomonas vaginalis tubulin, putative 0.0538 0.1044 0.2351
Echinococcus granulosus histone lysine methyltransferase setb 0.0241 0.0446 0.0444
Trichomonas vaginalis tubulin beta chain, putative 0.0538 0.1044 0.2351
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0047 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0185 0.0184
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0122 0.0121
Brugia malayi hypothetical protein 0.003 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0069 0.0102 0.0226
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Schistosoma mansoni protein phosphatase 2C 0.0028 0.0018 0.0018
Onchocerca volvulus Huntingtin homolog 0.0387 0.074 0.2114
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.007 0.0102 0.0227
Brugia malayi Tubulin alpha-2 chain 0.1342 0.2659 0.599
Giardia lamblia GTOR 0.0097 0.0157 0.044
Plasmodium vivax tubulin alpha chain, putative 0.1342 0.2659 0.7547
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0027 0.0074
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0045 0.0122
Echinococcus granulosus regulator of G protein signaling 7 0.0051 0.0065 0.0063
Loa Loa (eye worm) hypothetical protein 0.0096 0.0156 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Echinococcus multilocularis Polycystic kidney disease protein 0.0165 0.0293 0.0292
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0022 0.0007 0.0012
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0185 0.0184
Schistosoma mansoni hypothetical protein 0.0033 0.003 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-1 0.007 0.0102 0.0227
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0014 0.0153
Brugia malayi nuclear receptor RXR 0.003 0.0023 0.0049
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0042 0.009
Plasmodium vivax delta tubulin, putative 0.044 0.0847 0.24
Plasmodium falciparum histone acetyltransferase GCN5 0.0077 0.0118 0.033
Loa Loa (eye worm) hypothetical protein 0.0089 0.0142 0.0317
Echinococcus granulosus mixed lineage leukemia protein mll 0.0046 0.0056 0.0054
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0028 0.0018 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Entamoeba histolytica hypothetical protein 0.0044 0.0051 0.0139
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0056 0.0122
Mycobacterium ulcerans endonuclease IV 0.0079 0.0122 0.0272
Schistosoma mansoni hypothetical protein 0.0087 0.0137 0.0137
Entamoeba histolytica tubulin family protein 0.1771 0.3523 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.154 0.3058 0.689
Brugia malayi MH1 domain containing protein 0.012 0.0204 0.0457
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus granulosus follistatin 0.0062 0.0087 0.0085
Schistosoma mansoni tubulin subunit beta 0.044 0.0847 0.0846
Trichomonas vaginalis abcb9, putative 0.0023 0.0009 0.002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0331 0.0627 0.1409
Echinococcus granulosus expressed protein 0.0062 0.0087 0.0086
Echinococcus granulosus lysine specific demethylase 5A 0.0115 0.0193 0.0191
Loa Loa (eye worm) hypothetical protein 0.0411 0.0788 0.1772
Schistosoma mansoni tubulin subunit alpha 0.1342 0.2659 0.2659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.009
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Loa Loa (eye worm) hypothetical protein 0.0199 0.0363 0.0815
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.0014 0.0028
Brugia malayi TAZ zinc finger family protein 0.021 0.0385 0.0864
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0097 0.0157 0.0286
Giardia lamblia Hypothetical protein 0.009 0.0142 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Brugia malayi jmjC domain containing protein 0.0028 0.0018 0.0037
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0152
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0041 0.0045 0.0097
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0046 0.0056 0.0054
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.0014 0.0028
Loa Loa (eye worm) glutaminase 0.2227 0.4438 1
Trypanosoma brucei alpha tubulin 0.1342 0.2659 0.4905
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0071 0.0159
Echinococcus multilocularis 0.0026 0.0014 0.0012
Echinococcus multilocularis tubulin alpha 3 chain 0.1342 0.2659 0.2658
Schistosoma mansoni Smad4 0.0054 0.007 0.007
Plasmodium vivax tubulin epsilon chain, putative 0.1007 0.1987 0.5637
Loa Loa (eye worm) hypothetical protein 0.0165 0.0293 0.0658
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0056 0.0055
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0042 0.009
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0023 0.0049
Brugia malayi hypothetical protein 0.0696 0.1362 0.3067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0107 0.0241
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.006 0.0083 0.0081
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0143 0.025 0.0705
Echinococcus multilocularis tubulin epsilon chain 0.1007 0.1987 0.1985
Schistosoma mansoni hypothetical protein 0.0087 0.0137 0.0137
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0404 0.1142
Schistosoma mansoni hypothetical protein 0.0052 0.0068 0.0067
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.003 0.0028
Brugia malayi follicle stimulating hormone receptor 0.0265 0.0494 0.111
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0492 0.095 0.2139
Loa Loa (eye worm) jmjC domain-containing protein 0.0115 0.0193 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0051 0.0114
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0051 0.0049
Plasmodium falciparum importin beta, putative 0.003 0.0023 0.0062
Echinococcus multilocularis inositol monophosphatase 1 0.0062 0.0088 0.0086
Leishmania major hypothetical protein, conserved 0.0133 0.023 0.065
Echinococcus granulosus alpha tubulin 0.1342 0.2659 0.2658
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0041 0.0045 0.0043
Leishmania major DNA polymerase kappa, putative 0.0055 0.0072 0.02
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0091 0.0144 0.0143
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0023 0.0062
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.004 0.0042 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0071 0.0159
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0051 0.005
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0014 0.0153
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0111 0.0185 0.0521
Brugia malayi photoreceptor-specific nuclear receptor 0.007 0.0102 0.0227
Loa Loa (eye worm) hypothetical protein 0.1342 0.2659 0.599
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.004 0.0043 0.0077
Schistosoma mansoni ran 0.0022 0.0007 0.0007
Trypanosoma brucei beta tubulin 0.1771 0.3523 0.6498
Echinococcus granulosus beta tubulin 0.1771 0.3523 0.3522
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0051 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0137 0.0136
Schistosoma mansoni ferritin 0.0062 0.0087 0.0087
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.0014 0.0028
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0117 0.0263
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0009 0.031
Leishmania major zeta tubulin, putative 0.0746 0.1462 0.4148
Echinococcus multilocularis snurportin 1 0.0323 0.0612 0.061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0027 0.0058
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0091 0.0144 0.0143
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Trichomonas vaginalis conserved hypothetical protein 0.044 0.0847 0.1908
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0014 0.0153
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0027 0.0026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0115 0.0193 0.0193
Echinococcus multilocularis beta tubulin 0.1771 0.3523 0.3522
Onchocerca volvulus 0.0091 0.0144 0.0402
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0051 0.011
Echinococcus multilocularis CREB binding protein 0.0033 0.0029 0.0027
Leishmania major cytochrome p450-like protein 0.0026 0.0014 0.0035
Brugia malayi Doublecortin family protein 0.0165 0.0293 0.0658
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0144 0.0402
Brugia malayi Cytochrome P450 family protein 0.0026 0.0014 0.0028
Brugia malayi MH2 domain containing protein 0.0054 0.007 0.0155
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0478 0.0477
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Brugia malayi 6-phosphofructokinase 0.022 0.0404 0.0907
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Onchocerca volvulus 0.0091 0.0144 0.0402
Loa Loa (eye worm) hypothetical protein 0.0062 0.0087 0.0192
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0088 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.0037
Leishmania major beta tubulin 0.1771 0.3523 1
Brugia malayi jmjC domain containing protein 0.0028 0.0018 0.0037
Echinococcus multilocularis jun protein 0.0265 0.0496 0.0494
Loa Loa (eye worm) hypothetical protein 0.0092 0.0148 0.0329
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0014 0.0028
Echinococcus multilocularis jumonji domain containing 1A 0.0028 0.0018 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.0062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.006 0.0083 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0017 0.0035
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0041 0.0045 0.0043
Brugia malayi nuclear hormone receptor 0.003 0.0023 0.0049
Plasmodium vivax hypothetical protein, conserved 0.002 0.0003 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0014 0.0153
Onchocerca volvulus Protein ultraspiracle homolog 0.007 0.0102 0.0282
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0082 0.431
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0266 0.0496 0.0495
Echinococcus granulosus Tubulin beta 2C chain 0.1771 0.3523 0.3522
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Trypanosoma cruzi beta tubulin, putative 0.1771 0.3523 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.007 0.0102 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0018 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.0102 0.0227
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0056 0.0054
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0055 0.0072 0.0162
Leishmania major protein kinase, putative 0.0055 0.0073 0.0202
Leishmania major beta tubulin 0.1771 0.3523 1
Mycobacterium ulcerans DNA polymerase IV 0.0055 0.0072 0.0159
Echinococcus granulosus lipoxygenase domain containing protein 0.0165 0.0293 0.0292
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0091 0.0144 0.0143
Giardia lamblia DINP protein human, muc B family 0.0055 0.0072 0.02
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0035
Loa Loa (eye worm) hypothetical protein 0.0196 0.0356 0.0799
Echinococcus granulosus dnaJ subfamily B 0.1772 0.3524 0.3523
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0027 0.0074
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0042 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0107 0.0177 0.0396
Schistosoma mansoni agrin 0.0062 0.0087 0.0086
Mycobacterium ulcerans DNA polymerase IV 0.0055 0.0072 0.0159
Echinococcus multilocularis Tubulin beta 2C chain 0.1771 0.3523 0.3522
Echinococcus granulosus Niemann Pick C1 protein 0.0298 0.0561 0.056
Schistosoma mansoni DNA polymerase eta 0.0102 0.0167 0.0166
Schistosoma mansoni tubulin subunit beta 0.1771 0.3523 0.3523
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0006
Plasmodium vivax multidomain scavenger receptor, putative 0.0165 0.0293 0.0829
Schistosoma mansoni retinoic acid receptor RXR 0.007 0.0102 0.0102
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0011 0.0027
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0052
Brugia malayi nuclear receptor NHR-88 0.003 0.0023 0.0049
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0023 0.0049
Treponema pallidum cell division protein FtsZ 0.044 0.0847 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0185 0.0522
Schistosoma mansoni DNA helicase recq5 0.0041 0.0045 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0185 0.0418
Schistosoma mansoni myst-related protein 0.002 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0105 0.0173 0.0172
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0051 0.0065 0.0142
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0469 0.0905 0.2567
Schistosoma mansoni tar DNA-binding protein 0.007 0.0104 0.0104
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0088 0.0087
Brugia malayi jmjC domain containing protein 0.0115 0.0193 0.0431
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0056 0.0101
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.0494 0.111
Loa Loa (eye worm) transcription factor SMAD2 0.1766 0.3512 0.7913
Onchocerca volvulus 0.0023 0.0009 0.0013
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0028 0.0019 0.0019
Brugia malayi hypothetical protein 0.0208 0.0381 0.0856
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0014 0.0153
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0051 0.0049
Echinococcus granulosus mothers against decapentaplegic 5 0.012 0.0204 0.0203
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0118 0.033
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0097 0.0157 0.0155
Brugia malayi MH1 domain containing protein 0.0067 0.0096 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0569 0.1612
Schistosoma mansoni ferritin 0.0062 0.0087 0.0087
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0009 0.0007
Loa Loa (eye worm) agrin synaptic family protein 0.0062 0.0087 0.0192
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0137 0.0136
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0054 0.0071 0.0069
Mycobacterium ulcerans cell division protein FtsZ 0.044 0.0847 0.1905
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0071 0.0159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0115 0.0194 0.0192
Schistosoma mansoni cpg binding protein 0.0165 0.0293 0.0293
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0054 0.007 0.3697
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.003 0.0052
Trichomonas vaginalis glutathione reductase, putative 0.0054 0.007 0.0159
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0804 0.1578 0.3556
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0014 0.0035
Loa Loa (eye worm) hypothetical protein 0.0118 0.02 0.0447
Brugia malayi hypothetical protein 0.0165 0.0293 0.0658
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0072 0.013
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0077 0.0117 0.0328
Echinococcus granulosus CAAX prenyl protease 2 0.009 0.0142 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0018 0.0037
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0075 0.0209
Brugia malayi Muscleblind-like protein 0.0118 0.02 0.0447
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0014 0.0153
Loa Loa (eye worm) hypothetical protein 0.0258 0.0481 0.1081
Brugia malayi MH2 domain containing protein 0.012 0.0204 0.0457
Schistosoma mansoni hypothetical protein 0.2715 0.542 0.542
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0055 0.0072 0.0159
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0185 0.0414
Echinococcus granulosus lysine specific demethylase 6a 0.0028 0.0018 0.0017
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0097 0.0157 0.0286
Brugia malayi hypothetical protein 0.0039 0.0042 0.009
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Echinococcus granulosus leucine aminopeptidase protein 0.0111 0.0185 0.0184
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.0014 0.0028
Schistosoma mansoni tubulin subunit alpha 0.1342 0.2659 0.2659
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0023 0.0022
Echinococcus multilocularis tubulin alpha chain 0.1342 0.2659 0.2658
Brugia malayi CHE-14 protein 0.0089 0.0142 0.0317
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0017 0.0035
Schistosoma mansoni RAR-like nuclear receptor 0.007 0.0102 0.0102
Trichomonas vaginalis tubulin, putative 0.1771 0.3523 0.7938
Trichomonas vaginalis tubulin epsilon chain, putative 0.1771 0.3523 0.7938
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0009 0.0007
Echinococcus multilocularis tubulin alpha 3 chain 0.1342 0.2659 0.2658
Schistosoma mansoni glutaminase 0.2227 0.4438 0.4438
Brugia malayi Thioredoxin reductase 0.0155 0.0274 0.0615
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.00000000003393 0.000000000076452
Plasmodium falciparum LCCL domain-containing protein 0.0165 0.0293 0.0829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0093 0.0209
Echinococcus multilocularis leucine aminopeptidase protein 0.0111 0.0185 0.0184
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Echinococcus multilocularis zinc finger protein 0.0039 0.004 0.0038
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0014 0.0023
Schistosoma mansoni ran 0.0022 0.0007 0.0007
Echinococcus granulosus Tubulin alpha 1 chain 0.1342 0.2659 0.2658
Trichomonas vaginalis tubulin beta chain, putative 0.1342 0.2659 0.5992
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0056 0.0074 0.0073
Echinococcus multilocularis geminin 0.1256 0.2488 0.2486
Echinococcus granulosus lipoxygenase domain containing protein 0.0165 0.0293 0.0292
Schistosoma mansoni tubulin subunit alpha 0.044 0.0847 0.0846
Toxoplasma gondii beta-tubulin, putative 0.1771 0.3523 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0007 0.0006
Schistosoma mansoni ferritin light chain 0.0062 0.0087 0.0087
Echinococcus multilocularis RUN 0.0165 0.0293 0.0292
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0054 0.007 0.007
Loa Loa (eye worm) CYP4Cod1 0.0072 0.0107 0.0237
Mycobacterium ulcerans hypothetical protein 0.0021 0.0004 0.0006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0185 0.0522
Schistosoma mansoni single-minded 0.0208 0.038 0.0379
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0101 0.0225
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0009 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0115 0.0194 0.0192
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0027 0.0026
Echinococcus multilocularis Tubulin beta 2C chain 0.1771 0.3523 0.3522
Schistosoma mansoni rab6-interacting 0.0165 0.0293 0.0293
Brugia malayi hypothetical protein 0.0257 0.0478 0.1074
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0051 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.044 0.0847 0.1908
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.003 0.008
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0056 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.007 0.0102 0.0227
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0012 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0241 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.009
Echinococcus multilocularis muscleblind protein 1 0.0118 0.02 0.0199
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0054 0.007 0.0155
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Schistosoma mansoni terminal deoxycytidyl transferase 0.0055 0.0072 0.0072
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0082 0.0947
Echinococcus multilocularis tubulin alpha chain 0.1342 0.2659 0.2658
Plasmodium falciparum zinc finger protein, putative 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.1256 0.2488 0.2487
Loa Loa (eye worm) CBP-B 0.0149 0.0262 0.0586
Entamoeba histolytica hypothetical protein 0.0226 0.0416 0.1177
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.007 0.0102 0.0227
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Brugia malayi hypothetical protein 0.0091 0.0144 0.0322
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0051 0.0114
Brugia malayi mothers against decapentaplegic homolog 3 0.0054 0.007 0.0155
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0017 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.007 0.0102 0.0227
Onchocerca volvulus 0.0224 0.0412 0.1172
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0004 0.0004
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0056 0.0155
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0326 0.0618 0.1752
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0144 0.0404
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0017 0.0035
Brugia malayi N-terminal motif family protein 0.0143 0.025 0.0559
Echinococcus granulosus zinc finger protein 0.0039 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0092 0.0148 0.0329
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0062 0.0088 0.1021
Schistosoma mansoni hypothetical protein 0.0087 0.0137 0.0137
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0111 0.0185 0.2145
Onchocerca volvulus 0.003 0.0023 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0157 0.0353
Schistosoma mansoni 6-phosphofructokinase 0.022 0.0404 0.0403
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0185 0.0418
Onchocerca volvulus 0.0154 0.0272 0.0769
Loa Loa (eye worm) hypothetical protein 0.005 0.0064 0.014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0115 0.0193 0.0193
Brugia malayi phosphofructokinase 0.022 0.0404 0.0907
Toxoplasma gondii histone lysine methyltransferase SET1 0.0313 0.0591 0.1675
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0054 0.007 0.0127
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0028 0.0018 0.0018
Loa Loa (eye worm) intermediate filament protein 0.0199 0.0363 0.0815
Giardia lamblia Beta tubulin 0.1771 0.3523 1
Schistosoma mansoni cellular tumor antigen P53 0.0411 0.0788 0.0787
Brugia malayi Raf kinase 0.0045 0.0054 0.0117
Schistosoma mansoni nuclear receptor 0.003 0.0023 0.0023
Brugia malayi tailless protein 0.003 0.0023 0.0049
Echinococcus granulosus thioredoxin glutathione reductase 0.0155 0.0274 0.0273
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0227
Trichomonas vaginalis tubulin gamma chain, putative 0.1008 0.1988 0.4478
Leishmania major alpha tubulin 0.1342 0.2659 0.7547
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0135 0.0133
Echinococcus multilocularis TGF beta signal transducer SmadC 0.012 0.0204 0.0203
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0144 0.0322
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0051 0.011
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0023 0.0022
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0014 0.0035
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0051 0.011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0062 0.0088 0.0198
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0009 0.0007
Brugia malayi Pre-SET motif family protein 0.0224 0.0412 0.0926
Echinococcus granulosus CREB binding protein 0.0033 0.0029 0.0027
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0011 0.0027
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0027 0.0074
Onchocerca volvulus 0.0092 0.0148 0.0411
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.007 0.0102 0.0101
Schistosoma mansoni thyroid hormone receptor 0.007 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0093 0.0148 0.0331
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.007 0.0102 0.0102
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.003 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Onchocerca volvulus Alhambra homolog 0.0033 0.003 0.0073
Trypanosoma cruzi MFS transporter, putative 0.0091 0.0144 0.0406
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.009 0.0142 0.04
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0003 0.0005
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0051 0.0049
Schistosoma mansoni nuclear hormone receptor 0.003 0.0023 0.0023
Trypanosoma brucei beta tubulin 0.1771 0.3523 0.6498
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0009 0.002
Echinococcus multilocularis tubulin delta chain 0.044 0.0847 0.0845
Brugia malayi hypothetical protein 0.0078 0.0119 0.0265
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0071 0.0159
Loa Loa (eye worm) alpha-tubulin 0.1342 0.2659 0.599
Onchocerca volvulus 0.0052 0.0068 0.0182
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0115 0.0194 0.0433
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0072 0.0071
Brugia malayi hypoxia-induced factor 1 0.0642 0.1254 0.2822
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0056 0.0153
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0017 0.0035
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0011 0.0027
Trypanosoma brucei alpha tubulin 0.1342 0.2659 0.4905
Plasmodium vivax JmjC domain containing protein 0.0028 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Entamoeba histolytica hypothetical protein 0.0024 0.0011 0.0027
Brugia malayi Tubulin beta-1 chain 0.1771 0.3523 0.7937
Entamoeba histolytica CAAX prenyl protease family 0.009 0.0142 0.04
Echinococcus multilocularis 6 phosphofructokinase 0.022 0.0404 0.0402
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.007 0.0102 0.0101
Echinococcus granulosus tubulin alpha chain 0.1342 0.2659 0.2658
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0033 0.0073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0105 0.0173 0.0386
Echinococcus multilocularis regulator of G protein signaling 7 0.0051 0.0065 0.0063
Trichomonas vaginalis tubulin, putative 0.047 0.0906 0.2042
Trichomonas vaginalis tubulin gamma chain, putative 0.1771 0.3523 0.7938
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0115 0.0194 0.0192
Brugia malayi latrophilin 2 splice variant baaae 0.0226 0.0417 0.0936
Brugia malayi ecdysone receptor 0.003 0.0023 0.0049
Echinococcus granulosus jun protein 0.0265 0.0496 0.0494
Echinococcus granulosus tar DNA binding protein 0.007 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0018
Schistosoma mansoni patched 1 0.0089 0.0142 0.0142
Brugia malayi mbt repeat family protein 0.0055 0.0072 0.016
Trichomonas vaginalis tubulin, putative 0.0538 0.1044 0.2351
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0144 0.0404
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0004 0.0006
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0137 0.0137
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.0072 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-31 0.007 0.0102 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0033 0.0073
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0023 0.0049
Echinococcus multilocularis importin subunit beta 1 0.003 0.0023 0.0022
Brugia malayi MAP kinase sur-1 0.0111 0.0185 0.0414
Echinococcus multilocularis peregrin 0.0046 0.0055 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0133 0.023 0.065
Brugia malayi Intermediate filament tail domain containing protein 0.0199 0.0363 0.0815
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0009 0.002
Trypanosoma brucei zeta tubulin 0.0746 0.1462 0.2695
Leishmania major beta tubulin 0.1771 0.3523 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.0016
Loa Loa (eye worm) glutaminase 2 0.2227 0.4438 1
Brugia malayi bZIP transcription factor family protein 0.0265 0.0496 0.1114
Leishmania major cytochrome p450-like protein 0.0026 0.0014 0.0035
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0062 0.0087 0.1017
Trichomonas vaginalis tubulin alpha chain, putative 0.0978 0.1928 0.4344
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0115 0.0194 0.0433
Brugia malayi cytochrome P450 0.0026 0.0014 0.0028
Echinococcus granulosus 6 phosphofructokinase 0.022 0.0404 0.0402
Entamoeba histolytica tubulin gamma chain 0.1008 0.1988 0.564
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0091 0.0144 0.0322
Trypanosoma cruzi zeta tubulin, putative 0.0746 0.1462 0.4148
Echinococcus granulosus dna polymerase eta 0.0102 0.0167 0.0165
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0073 0.0202
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0341 0.0765
Trichomonas vaginalis abcb9, putative 0.0023 0.0009 0.002
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0088 0.0086
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0023 0.0049
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0028 0.0018 0.0031
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0009 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.007 0.0196
Trichomonas vaginalis tubulin epsilon chain, putative 0.044 0.0847 0.1908
Onchocerca volvulus 0.0165 0.0293 0.083
Brugia malayi Niemann-Pick C1 protein precursor 0.0208 0.0381 0.0856
Echinococcus multilocularis regulator of G protein signaling 7 0.0051 0.0065 0.0063
Schistosoma mansoni steroid hormone receptor ad4bp 0.007 0.0102 0.0102
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0028 0.0018 0.0047
Brugia malayi Pax transcription factor protein 2 0.026 0.0485 0.1089
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0055 0.0072 0.0071
Echinococcus granulosus ferritin 0.0062 0.0087 0.0086
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.0102 0.0101
Echinococcus multilocularis muscleblind protein 0.0118 0.02 0.0199
Schistosoma mansoni hypothetical protein 0.0165 0.0293 0.0293
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.009 0.0142 0.0142
Echinococcus multilocularis FTZ F1 alpha 0.007 0.0102 0.0101
Loa Loa (eye worm) acetyltransferase 0.0293 0.0551 0.1238
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0107 0.0299
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Echinococcus granulosus tubulin alpha 0.0978 0.1928 0.1927
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0054 0.007 0.0155
Schistosoma mansoni alpha tubulin 0.1342 0.2659 0.2659
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0054 0.007 0.0196
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0051 0.005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0062 0.0087 0.0192
Schistosoma mansoni tar DNA-binding protein 0.007 0.0104 0.0104
Schistosoma mansoni smad1 5 8 and 0.012 0.0204 0.0204
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0091 0.0254
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0009 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0341 0.0765
Schistosoma mansoni hypothetical protein 0.0086 0.0136 0.0135
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.021 0.0385 0.0385
Echinococcus granulosus Tubulin beta 2C chain 0.1771 0.3523 0.3522
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0017 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-40 0.007 0.0102 0.0227
Mycobacterium tuberculosis Probable oxidoreductase 0.0394 0.0753 0.8896
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0022 0.0007 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.007 0.0102 0.0227
Echinococcus granulosus regulator of G protein signaling 7 0.0051 0.0065 0.0063
Brugia malayi multidrug resistance protein 3 0.0023 0.0009 0.0017
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0051 0.0049
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0188 0.0341 0.034
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0097 0.0157 0.044
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0097 0.0157 0.044
Leishmania major beta tubulin 0.1771 0.3523 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.003 0.0028
Brugia malayi MH2 domain containing protein 0.1766 0.3512 0.7913
Schistosoma mansoni ferritin 0.0062 0.0087 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0569 0.1283
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.0014 0.0028
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.0014 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.1766 0.3512 0.7913
Plasmodium falciparum thioredoxin reductase 0.0155 0.0274 0.0775
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0009 0.0007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.003 0.0028
Schistosoma mansoni apoferritin-2 0.0062 0.0087 0.0087
Onchocerca volvulus Bile acid receptor homolog 0.007 0.0102 0.0282
Loa Loa (eye worm) Smad1 0.012 0.0204 0.0457
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0003 0.0005
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.003 0.0022 0.0051
Giardia lamblia Alpha-tubulin 0.1342 0.2659 0.7547
Schistosoma mansoni lamin 0.0199 0.0363 0.0363
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0072 0.013
Entamoeba histolytica hypothetical protein 0.0025 0.0012 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0188 0.0341 0.0964
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0014 0.0035
Echinococcus granulosus Tubulin beta 2C chain 0.1771 0.3523 0.3522
Schistosoma mansoni coup transcription factor 0.007 0.0102 0.0102
Echinococcus multilocularis lamin dm0 0.0199 0.0363 0.0362
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0009 0.0017
Onchocerca volvulus 0.0091 0.0144 0.0402
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0072 0.0072
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0028 0.0019 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0049
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.003 0.008
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0014 0.0012
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0185 0.0184
Schistosoma mansoni nuclear receptor 0.003 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0067 0.0151
Echinococcus granulosus tubulin alpha chain 0.1342 0.2659 0.2658
Echinococcus multilocularis neuropeptide s receptor 0.0986 0.1944 0.1943
Brugia malayi PHD-finger family protein 0.0044 0.005 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0082 0.0184
Onchocerca volvulus 0.0091 0.0144 0.0402
Echinococcus multilocularis mothers against decapentaplegic 6 0.0054 0.007 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0091 0.0144 0.0322
Loa Loa (eye worm) tubulin alpha-3 chain 0.0804 0.1578 0.3553
Loa Loa (eye worm) RecQ helicase 0.0069 0.01 0.0223
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0185 0.0522
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0031 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0051 0.011
Schistosoma mansoni tar DNA-binding protein 0.007 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0062 0.0087 0.0192
Brugia malayi Nuclear hormone receptor E75 0.003 0.0023 0.0049
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0003 0.0003
Brugia malayi glutaminase DH11.1 0.2227 0.4438 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0045 0.0097
Giardia lamblia NADH oxidase lateral transfer candidate 0.0054 0.007 0.0196
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0048 0.0105
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0016
Leishmania major DNA polymerase eta, putative 0.0064 0.0091 0.0254
Schistosoma mansoni ferritin light chain 0.0062 0.0087 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0224 0.0412 0.0412
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.003 0.008
Brugia malayi conserved hypotetical protein 0.003 0.0023 0.0049
Giardia lamblia Epsilon tubulin 0.0469 0.0905 0.2567
Brugia malayi Smad1 0.012 0.0204 0.0457
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.0014 0.0028
Echinococcus multilocularis tubulin alpha 0.0978 0.1928 0.1927
Loa Loa (eye worm) hypothetical protein 0.0062 0.0087 0.0192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0042 0.0041
Brugia malayi CXXC zinc finger family protein 0.0154 0.0272 0.061
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0009 0.002
Echinococcus granulosus CREB binding protein 0.021 0.0385 0.0383
Onchocerca volvulus 0.0208 0.0381 0.1082
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0062 0.0087 0.0982
Brugia malayi tubulin alpha-2 chain 0.1342 0.2659 0.599
Loa Loa (eye worm) tubulin alpha-2 chain 0.1342 0.2659 0.599
Schistosoma mansoni nuclear hormone receptor 0.003 0.0023 0.0023
Trypanosoma brucei epsilon tubulin 0.1007 0.1987 0.3663
Plasmodium falciparum tubulin delta chain, putative 0.044 0.0847 0.24
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0088 0.0194
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0072 0.013
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0022 0.0007 0.0005
Echinococcus granulosus Tubulin beta 2C chain 0.1771 0.3523 0.3522
Toxoplasma gondii NADPH-glutathione reductase 0.0054 0.007 0.0196
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0657 0.1283 0.1282
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0028 0.0019 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.0037
Trichomonas vaginalis mercuric reductase, putative 0.0054 0.007 0.0159
Mycobacterium ulcerans glutaminase 0.2227 0.4438 1
Brugia malayi TAR-binding protein 0.007 0.0104 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0078 0.0177
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0023 0.0023
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0009 0.0007
Brugia malayi PXA domain containing protein 0.0044 0.0051 0.011
Brugia malayi Isocitrate dehydrogenase 0.0033 0.003 0.0063
Treponema pallidum NADH oxidase 0.0054 0.007 0.0815
Echinococcus granulosus tubulin alpha 1C chain 0.1342 0.2659 0.2658
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0009 0.0021

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 8.7 Potency of the compound was determined against histamine H1 receptor on guinea pig ileum ChEMBL. 7650688
Ki (binding) = -7.91 Inhibition of [3H]-mepyramine binding with histamine H1 receptor in guinea pig cerebellum membranes after 30 min ChEMBL. 7650688

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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