Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glutamate receptor | 0.0102 | 0.1109 | 0.1411 |
Schistosoma mansoni | P2X receptor subunit | 0.0134 | 0.1525 | 0.1712 |
Onchocerca volvulus | 0.0038 | 0.0283 | 0.1494 | |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0024 | 0.0104 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0649 | 0.0822 |
Entamoeba histolytica | Ran family GTPase | 0.0043 | 0.0342 | 0.2325 |
Echinococcus granulosus | tar DNA binding protein | 0.0327 | 0.402 | 0.4518 |
Echinococcus granulosus | snurportin 1 | 0.062 | 0.7809 | 0.8778 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0024 | 0.0104 | 0.0115 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0283 | 0.0631 |
Echinococcus granulosus | microtubule associated protein 2 | 0.07 | 0.8852 | 0.9951 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0088 | 0.0191 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0042 | 0.0334 | 0.0332 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0043 | 0.0342 | 0.6317 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.1345 | 0.2995 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0283 | 0.0701 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1712 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0017 | 0.0008 | 0.0006 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0283 | 0.7104 |
Schistosoma mansoni | P2X receptor subunit | 0.0134 | 0.1525 | 0.1712 |
Echinococcus multilocularis | Smad4 | 0.0017 | 0.0008 | 0.0006 |
Brugia malayi | hypothetical protein | 0.0108 | 0.1182 | 0.2936 |
Trichomonas vaginalis | ran, putative | 0.0043 | 0.0342 | 0.8581 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0283 | 0.0631 |
Echinococcus multilocularis | tyrosine kinase | 0.0024 | 0.0104 | 0.0103 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.054 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.062 | 0.7809 | 0.7808 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0088 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0006 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0283 | 0.7023 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0088 | 0.2141 |
Schistosoma mansoni | protein kinase | 0.0024 | 0.0104 | 0.0115 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0143 | 0.0142 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.0008 | 0.0007 |
Brugia malayi | TAR-binding protein | 0.0327 | 0.402 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0259 | 0.3143 | 0.7818 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.157 | 0.1763 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0283 | 0.0627 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0403 | 0.0897 |
Echinococcus multilocularis | tar DNA binding protein | 0.0327 | 0.402 | 0.4019 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0066 | 0.0649 | 0.0822 |
Loa Loa (eye worm) | TAR-binding protein | 0.0327 | 0.402 | 0.5143 |
Echinococcus granulosus | smad | 0.0017 | 0.0008 | 0.0007 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1523 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0321 | 0.0359 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0423 | 0.1047 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.1182 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0283 | 0.7104 |
Schistosoma mansoni | microtubule-associated protein tau | 0.07 | 0.8852 | 0.9951 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0088 | 0.0103 |
Echinococcus granulosus | Smad4 | 0.0017 | 0.0008 | 0.0007 |
Brugia malayi | MH2 domain containing protein | 0.0248 | 0.2996 | 0.7452 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1022 | 0.1147 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0217 | 0.2599 | 0.292 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0088 | 0.0195 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0283 | 0.0631 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0104 | 0.0154 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0363 | 0.4491 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0138 | 0.157 | 0.2002 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0095 | 0.1022 | 0.102 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0141 | 0.2588 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0469 | 0.5862 | 0.5861 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0469 | 0.5862 | 0.6589 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0024 | 0.0104 | 0.0103 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0002 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0704 | 0.8896 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1398 | 0.1782 |
Schistosoma mansoni | tar DNA-binding protein | 0.0327 | 0.402 | 0.4518 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.062 | 0.7809 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0124 | 0.1398 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0283 | 0.0631 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.1029 | 0.2556 |
Schistosoma mansoni | tar DNA-binding protein | 0.0327 | 0.402 | 0.4518 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0126 | 0.1424 | 0.1599 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.157 | 0.1763 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0283 | 0.0701 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.024 | 0.2895 | 0.3253 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0024 | 0.0104 | 0.2561 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0334 | 0.0373 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.157 | 0.1568 |
Onchocerca volvulus | 0.0027 | 0.0143 | 0.0424 | |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0115 |
Loa Loa (eye worm) | glutamate receptor | 0.0259 | 0.3143 | 0.4019 |
Schistosoma mansoni | tyrosine kinase | 0.0024 | 0.0104 | 0.0115 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0283 | 0.0631 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0248 | 0.2996 | 0.3831 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0396 | 0.0395 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0047 | 0.0398 | 0.9886 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1523 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0469 | 0.5862 | 0.5861 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0283 | 0.0701 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0321 | 0.0319 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0283 | 0.0282 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0088 | 0.0191 |
Leishmania major | extracellular receptor, putative | 0.0024 | 0.0104 | 0.2561 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0012 | 0.0193 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0302 | 0.0337 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0141 | 0.3475 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0024 | 0.0104 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0137 | 0.0166 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0321 | 0.0319 |
Echinococcus granulosus | lamin | 0.0027 | 0.0143 | 0.0159 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0334 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0441 | 0.0555 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0301 | 0.3685 | 0.4714 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1022 | 0.13 |
Schistosoma mansoni | hypothetical protein | 0.062 | 0.7809 | 0.8778 |
Brugia malayi | RNA, U transporter 1 | 0.0165 | 0.1925 | 0.4787 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0141 | 0.2588 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0403 | 0.0998 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0088 | 0.0214 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0065 | 0.0624 | 0.0622 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0141 | 0.3475 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0624 | 0.079 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.1189 | 0.2648 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0403 | 0.7447 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0024 | 0.0104 | 0.0115 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0283 | 0.1557 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1398 | 0.3475 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0283 | 0.0317 |
Echinococcus granulosus | importin subunit beta 1 | 0.0058 | 0.054 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0141 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.2895 | 0.3701 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0283 | 0.0627 |
Brugia malayi | RNA binding protein | 0.0327 | 0.402 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0088 | 0.0214 |
Schistosoma mansoni | lamin | 0.0027 | 0.0143 | 0.0159 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0283 | 0.0317 |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0363 | 0.4491 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0403 | 0.7447 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0143 | 0.0174 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1712 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0141 | 0.2588 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0016 | 0.0036 |
Onchocerca volvulus | 0.0049 | 0.0423 | 0.2556 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0108 | 0.1182 | 0.118 |
Schistosoma mansoni | Smad4 | 0.0017 | 0.0008 | 0.0007 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.1189 | 0.2648 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0024 | 0.0104 | 0.0256 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0143 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1398 | 0.1782 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.1048 | 0.1176 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.1345 | 0.2995 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0006 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0143 | 0.0159 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0126 | 0.1424 | 0.3539 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.157 | 0.1763 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.1182 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0017 | 0.0008 | 0.0007 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.0008 | 0.0007 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0342 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0403 | 0.0401 |
Schistosoma mansoni | tyrosine kinase | 0.0024 | 0.0104 | 0.0115 |
Brugia malayi | hypothetical protein | 0.024 | 0.2895 | 0.72 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0302 | 0.0337 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0095 | 0.1022 | 0.2539 |
Echinococcus granulosus | geminin | 0.0704 | 0.8896 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0342 | 0.8483 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0012 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1523 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0398 | 0.2839 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0134 | 0.1525 | 0.1712 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.1189 | 0.8758 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0248 | 0.2996 | 0.3831 |
Schistosoma mansoni | lamin | 0.0027 | 0.0143 | 0.0159 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0301 | 0.3685 | 0.9167 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0115 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0024 | 0.0104 | 0.0115 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0088 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0006 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0095 | 0.1022 | 0.13 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0283 | 0.523 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0024 | 0.0104 | 0.0103 |
Echinococcus granulosus | potassium voltage gated channel subfamily KQT | 0.0065 | 0.0624 | 0.07 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0423 | 0.0473 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0024 | 0.0104 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0043 | 0.0342 | 0.6317 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0103 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0024 | 0.0104 | 0.0115 |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0065 | 0.0624 | 0.079 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0319 | 0.3918 | 0.3917 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0403 | 0.7447 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0095 | 0.1022 | 0.2539 |
Echinococcus granulosus | tyrosine kinase | 0.0024 | 0.0104 | 0.0115 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0088 | 0.0191 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0141 | 0.2588 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.1182 | 1 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0141 | 0.0347 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0042 | 0.0334 | 0.0373 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0095 | 0.1022 | 0.102 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.0008 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.1182 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0704 | 0.8896 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.07 | 0.8852 | 0.8852 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0088 | 0.0191 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0283 | 0.0631 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0088 | 0.0191 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0088 | 0.0191 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0403 | 0.7447 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0403 | 1 |
Echinococcus multilocularis | smad | 0.0017 | 0.0008 | 0.0006 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0143 | 0.0352 |
Onchocerca volvulus | 0.0024 | 0.0104 | 0.0129 | |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.1561 | 0.1753 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0283 | 0.0631 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0138 | 0.157 | 0.3902 |
Echinococcus granulosus | glutamate receptor 2 | 0.0024 | 0.0104 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0302 | 0.0337 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0283 | 0.7023 |
Schistosoma mansoni | tar DNA-binding protein | 0.0327 | 0.402 | 0.4518 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0143 | 0.0352 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0088 | 0.2141 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.157 | 0.1763 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.1029 | 0.1155 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0283 | 0.0631 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0624 | 0.079 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0058 | 0.054 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0283 | 0.1557 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0042 | 0.0334 | 0.0826 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0006 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0095 | 0.1022 | 0.1147 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0143 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1022 | 0.1147 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0321 | 0.0402 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0403 | 0.7447 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0024 | 0.0104 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0321 | 0.0402 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0024 | 0.0104 | 0.0256 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0043 | 0.0342 | 0.0383 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0012 | 0.0023 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0321 | 0.0359 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0017 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0143 | 0.0174 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.0008 | 0.0007 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0283 | 0.7104 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 0.2452 | 0.3134 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0295 | 0.3603 | 0.4049 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0141 | 0.3475 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0143 | 0.0159 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0206 | 0.2452 | 0.6099 |
Leishmania major | importin beta-1 subunit, putative | 0.0047 | 0.0398 | 0.9886 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0058 | 0.054 | 0.0539 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0283 | 0.7023 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0283 | 0.0354 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1022 | 0.1147 |
Echinococcus granulosus | GPCR family 2 | 0.0095 | 0.1022 | 0.1147 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0012 | 0.0193 |
Plasmodium vivax | importin-beta 2, putative | 0.0058 | 0.054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0319 | 0.3918 | 0.5013 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0143 | 0.1645 | 0.1644 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0143 | 0.1645 | 0.1848 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0342 | 0.6317 |
Loa Loa (eye worm) | RNA binding protein | 0.0327 | 0.402 | 0.5143 |
Schistosoma mansoni | P2X receptor subunit | 0.0134 | 0.1525 | 0.1712 |
Leishmania major | GTP-binding protein, putative | 0.0043 | 0.0342 | 0.8483 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.1561 | 0.1559 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0403 | 0.0451 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0088 | 0.0214 |
Onchocerca volvulus | 0.0038 | 0.0283 | 0.1494 | |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0423 | 0.0473 |
Schistosoma mansoni | tar DNA-binding protein | 0.0327 | 0.402 | 0.4518 |
Schistosoma mansoni | importin beta-1 | 0.0058 | 0.054 | 0.0606 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.1345 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1022 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0403 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0283 | 0.7104 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0235 | 0.2828 | 0.7033 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.0008 | 0.0014 |
Schistosoma mansoni | ran | 0.0043 | 0.0342 | 0.0383 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0403 | 0.7447 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0342 | 0.0847 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0141 | 0.2588 |
Trichomonas vaginalis | importin beta-1, putative | 0.0047 | 0.0398 | 1 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0342 | 0.0429 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0321 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1029 | 0.1309 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0398 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0088 | 0.0103 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0319 | 0.3918 | 0.4404 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0024 | 0.0104 | 0.0103 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.1029 | 0.1027 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.1345 | 0.2995 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0302 | 0.0337 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0024 | 0.0104 | 0.0115 |
Onchocerca volvulus | 0.0024 | 0.0104 | 0.0129 | |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.1189 | 0.2648 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0024 | 0.0104 | 0.0103 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0283 | 0.0701 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0042 | 0.0334 | 0.1876 |
Brugia malayi | Smad1 | 0.0017 | 0.0008 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0206 | 0.2452 | 0.2755 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0104 | 0.0256 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0002 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.157 | 0.1763 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0398 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.157 | 0.1568 |
Echinococcus multilocularis | geminin | 0.0704 | 0.8896 | 0.8895 |
Echinococcus multilocularis | GPCR, family 2 | 0.0095 | 0.1022 | 0.102 |
Schistosoma mansoni | P2X receptor subunit | 0.0134 | 0.1525 | 0.1712 |
Schistosoma mansoni | ran | 0.0043 | 0.0342 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.3685 | 0.4714 |
Plasmodium falciparum | importin beta, putative | 0.0058 | 0.054 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0954 | 0.0952 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.024 | 0.2895 | 0.2893 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0283 | 0.523 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0002 | 0.5 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.1189 | 0.2648 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.054 | 0.0683 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0283 | 0.0354 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0403 | 0.0998 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0108 | 0.1182 | 0.1327 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0283 | 0.0627 |
Echinococcus granulosus | glutamate receptor 2 | 0.0024 | 0.0104 | 0.0115 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.1029 | 0.8604 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0283 | 0.0317 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0024 | 0.0104 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0088 | 0.0103 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0342 | 0.6317 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0143 | 0.0159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0321 | 0.8054 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0403 | 0.0507 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0283 | 0.0631 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0141 | 0.1614 | 0.2059 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.1189 | 0.2648 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.1189 | 0.2648 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0002 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0088 | 0.2141 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0283 | 0.0627 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0327 | 0.402 | 0.5143 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0104 | 0.0124 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0066 | 0.0649 | 0.161 |
Onchocerca volvulus | 0.0027 | 0.0143 | 0.0424 | |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0283 | 0.7104 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.1182 | 0.1327 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0244 | 0.2947 | 0.6562 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0024 | 0.0104 | 0.0129 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0024 | 0.0104 | 0.0124 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0217 | 0.2599 | 0.2598 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0143 | 0.1645 | 0.1848 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.0008 | 0.0014 |
Schistosoma mansoni | tar DNA-binding protein | 0.0327 | 0.402 | 0.4518 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0108 | 0.1182 | 0.1327 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0042 | 0.0334 | 0.1876 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0283 | 0.0627 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0321 | 0.0795 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0283 | 0.523 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0143 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0006 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0043 | 0.0342 | 0.034 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.0008 | 0.0014 |
Echinococcus granulosus | neuropeptide s receptor | 0.0469 | 0.5862 | 0.6589 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0143 | 0.1645 | 0.409 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0017 | 0.0008 | 0.0006 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0095 | 0.1022 | 0.1147 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0066 | 0.0649 | 0.0822 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0342 | 0.8483 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0954 | 0.107 |
Onchocerca volvulus | Huntingtin homolog | 0.0124 | 0.1398 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0217 | 0.2599 | 0.292 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0017 | 0.0008 | 0.0007 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0283 | 0.7104 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0403 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0301 | 0.3685 | 0.9167 |
Onchocerca volvulus | 0.0038 | 0.0283 | 0.1494 | |
Brugia malayi | Importin beta-1 subunit | 0.0058 | 0.054 | 0.134 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0283 | 0.0631 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0088 | 0.0195 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0012 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0354 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0024 | 0.0104 | 0.0103 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0327 | 0.402 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.054 | 1 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0024 | 0.0104 | 0.0256 |
Schistosoma mansoni | smad | 0.0017 | 0.0008 | 0.0007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.