Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0041 | 0.0802 | 0.3136 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1086 | 0.1186 |
Onchocerca volvulus | 0.0076 | 0.1928 | 0.4441 | |
Brugia malayi | CHE-14 protein | 0.0041 | 0.079 | 0.0985 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0076 | 0.1928 | 0.2105 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0034 | 0.0556 | 0.0496 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0066 | 0.1587 | 0.4672 |
Giardia lamblia | Methyltransferase like 2 | 0.0025 | 0.0266 | 0.0534 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0957 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0087 | 0.2263 | 0.6337 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0107 | 0.0133 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0087 | 0.2263 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0976 | 0.0878 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.2539 | 0.2458 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.2447 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.9158 | 0.9149 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0087 | 0.2263 | 0.6337 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.899 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0.0876 | 0.2579 |
Schistosoma mansoni | methyltransferase-related | 0.0025 | 0.0266 | 0.0176 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0067 | 0.1622 | 0.1812 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0079 | 0.202 | 0.2291 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0122 | 0.3398 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.002 | 0.0135 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.1939 | 0.1852 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0.0876 | 0.2579 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0.0876 | 0.318 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0043 | 0.0876 | 0.0914 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Onchocerca volvulus | Peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.002 | 0.0135 | 0.055 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0066 | 0.1587 | 0.4155 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0946 | 0.1033 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.079 | 0.0863 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.11 | 0.1098 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.2539 | 0.3163 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.079 | 0.0691 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.2447 | 0.5709 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0107 | 0.0133 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0033 | 0.0552 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.3942 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Schistosoma mansoni | kinase | 0.0047 | 0.0986 | 0.0971 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0144 | 0.0037 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.079 | 0.0691 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0107 | 0.0117 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0043 | 0.0876 | 0.0914 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.3853 | 0.3787 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0678 | 0.0577 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.2447 | 0.2585 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | expressed conserved protein | 0.0089 | 0.2353 | 0.227 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0107 | 0.0133 |
Echinococcus granulosus | expressed conserved protein | 0.0089 | 0.2353 | 0.227 |
Mycobacterium leprae | conserved hypothetical protein | 0.0043 | 0.0876 | 0.1859 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.141 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0079 | 0.202 | 0.2291 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.1525 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1552 | 0.1597 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0107 | 0.0117 |
Onchocerca volvulus | Peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0595 | 0.0493 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Echinococcus multilocularis | jun protein | 0.0171 | 0.4971 | 0.4917 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0107 | 0.0133 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0.0876 | 0.3484 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0266 | 0.0534 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.3853 | 0.3787 |
Echinococcus granulosus | death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.079 | 0.0863 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.2447 | 0.2672 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.1939 | 0.2416 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Onchocerca volvulus | Dual oxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.002 | 0.0135 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0876 | 0.1092 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0025 | 0.0266 | 0.0332 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0211 | 0.0295 |
Brugia malayi | RNA binding protein | 0.0076 | 0.1939 | 0.2416 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0087 | 0.2263 | 0.2584 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0076 | 0.1928 | 0.218 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Loa Loa (eye worm) | acyl carrier protein | 0.0037 | 0.0683 | 0.0745 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.079 | 0.0691 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0295 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3542 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0295 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0043 | 0.0876 | 0.0914 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.002 | 0.0135 | 0.0147 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.002 | 0.0135 | 0.0168 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0043 | 0.0876 | 0.0914 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0068 | 0.1663 | 0.1861 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0087 | 0.2263 | 0.666 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0046 | 0.0959 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0054 | 0.1211 | 0.3565 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0383 | 0.0418 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0383 | 0.1167 |
Schistosoma mansoni | jun-related protein | 0.0139 | 0.3942 | 0.4237 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0144 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0107 | 0.0133 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0777 |
Brugia malayi | Peroxidasin | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.1552 | 0.1934 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.1552 | 0.5881 |
Brugia malayi | Death domain containing protein | 0.0033 | 0.0552 | 0.0688 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0947 | 0.3487 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0144 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0107 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0087 | 0.2263 | 0.6337 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0.0876 | 0.2579 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0033 | 0.0552 | 0.0492 |
Mycobacterium ulcerans | polyketide synthase | 0.0087 | 0.2263 | 0.666 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0595 | 0.0493 |
Echinococcus multilocularis | peroxidasin | 0.0026 | 0.0302 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0383 | 0.3011 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0043 | 0.0876 | 0.1092 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0068 | 0.1663 | 0.4398 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.002 | 0.0135 | 0.0396 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1552 | 0.1695 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0383 | 0.3011 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0383 | 0.0279 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.1939 | 0.1852 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.002 | 0.0135 | 0.055 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Schistosoma mansoni | ets-related | 0.0265 | 0.8026 | 0.8749 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.9158 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0046 | 0.0959 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.1939 | 0.2118 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0046 | 0.0959 | 0.3921 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1383 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.2447 | 0.2365 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0947 | 0.3487 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Onchocerca volvulus | Netrin receptor homolog | 0.0033 | 0.0552 | 0.1086 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0876 | 0.318 |
Schistosoma mansoni | gabp alpha | 0.0087 | 0.2292 | 0.2414 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0081 | 0.21 | 0.2617 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0154 | 0.4449 | 0.5544 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0876 | 0.085 |
Onchocerca volvulus | 0.0134 | 0.3791 | 0.8987 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0046 | 0.0959 | 0.0862 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0678 | 0.0577 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.1461 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0107 | 0.0133 |
Echinococcus granulosus | Ankyrin | 0.0034 | 0.0556 | 0.0454 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3921 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.079 | 0.0755 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0087 | 0.2292 | 0.2503 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.2586 | 0.2739 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0046 | 0.0968 | 0.1024 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0028 | 0.0378 | 0.0314 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1196 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0266 | 0.1089 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.002 | 0.0135 | 0.0028 |
Echinococcus granulosus | peroxidasin | 0.0026 | 0.0302 | 0.0197 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.2539 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0026 | 0.0302 | 0.0475 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1048 |
Mycobacterium ulcerans | thioesterase | 0.0068 | 0.1663 | 0.4893 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.1939 | 0.2416 |
Loa Loa (eye worm) | fatty acid synthase | 0.008 | 0.2065 | 0.2255 |
Schistosoma mansoni | peroxidasin | 0.0026 | 0.0302 | 0.0215 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0026 | 0.03 | 0.0221 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Brugia malayi | Blistered cuticle protein 3 | 0.0026 | 0.0302 | 0.0376 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.002 | 0.0135 | 0.003 |
Echinococcus granulosus | jun protein | 0.0171 | 0.4971 | 0.4917 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0383 | 0.0305 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0046 | 0.0959 | 0.3406 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0383 | 0.1565 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.482 | 0.5264 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0033 | 0.0552 | 0.045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0107 | 0.0117 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0383 | 0.0477 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0081 | 0.21 | 0.581 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0556 | 0.0608 |
Schistosoma mansoni | ran | 0.0021 | 0.0144 | 0.004 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0054 | 0.1211 | 0.2941 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0.0876 | 0.2579 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0107 | 0.0133 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0058 | 0.1344 | 0.5682 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0053 | 0.1178 | 0.4903 |
Echinococcus multilocularis | Ankyrin | 0.0034 | 0.0556 | 0.0454 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.079 | 0.2808 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.2447 | 0.9617 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.2055 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0046 | 0.0959 | 0.0862 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0876 | 0.1092 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2539 | 0.2772 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0026 | 0.03 | 0.0884 |
Onchocerca volvulus | Peroxidasin homolog | 0.0026 | 0.0302 | 0.0475 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0777 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | peroxidasin | 0.0026 | 0.0302 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Loa Loa (eye worm) | fli-1 protein | 0.0265 | 0.8026 | 0.8764 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1383 | 0.5652 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Brugia malayi | beta-lactamase | 0.0043 | 0.0876 | 0.1092 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0122 | 0.3398 | 0.3951 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0054 | 0.1211 | 0.3565 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0025 | 0.0266 | 0.018 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0864 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.1461 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3542 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.6344 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.002 | 0.0135 | 0.055 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0179 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0025 | 0.0283 | 0.0199 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.2539 | 0.2458 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.002 | 0.0135 | 0.055 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0026 | 0.0302 | 0.0329 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1196 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0552 | 0.0492 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0107 | 0.0133 |
Loa Loa (eye worm) | beta-lactamase | 0.0043 | 0.0876 | 0.0957 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0081 | 0.21 | 0.2388 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0383 | 0.0279 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0107 | 0.0133 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.1939 | 0.2118 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.002 | 0.0135 | 0.0396 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.002 | 0.0135 | 0.0396 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0087 | 0.2263 | 0.2584 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0059 | 0.1361 | 0.1498 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.2447 | 0.2365 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.9158 | 0.9149 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0025 | 0.0283 | 0.0832 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0876 | 0.318 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0046 | 0.0959 | 0.0942 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.5866 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3884 | 0.4241 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0122 | 0.3398 | 1 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.002 | 0.0135 | 0.0028 |
Brugia malayi | Ets-domain containing protein | 0.0087 | 0.2292 | 0.2856 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.079 | 0.0691 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0046 | 0.0959 | 0.3921 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0033 | 0.0537 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1884 | 0.2057 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0043 | 0.0876 | 0.0914 |
Mycobacterium ulcerans | polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0107 | 0.0117 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0107 | 0.0133 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0283 | 0.0352 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0108 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.2447 | 0.3049 |
Onchocerca volvulus | 0.0142 | 0.4043 | 0.9602 | |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0383 | 0.1565 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0033 | 0.0552 | 0.0688 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0081 | 0.21 | 0.2388 |
Brugia malayi | AMP-binding enzyme family protein | 0.0076 | 0.1928 | 0.2402 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0033 | 0.0552 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0552 | 0.0603 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3921 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Echinococcus multilocularis | geminin | 0.0205 | 0.6065 | 0.6023 |
Brugia malayi | Uncoordinated protein 44 | 0.0033 | 0.0552 | 0.0688 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0107 | 0.0133 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0081 | 0.21 | 0.581 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0107 | 0.0133 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.1939 | 0.2118 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0147 | 0.4206 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1383 | 0.129 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0144 | 0.0037 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0087 | 0.2263 | 0.666 |
Mycobacterium ulcerans | thioesterase TesA | 0.0068 | 0.1663 | 0.4893 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0107 | 0.0133 |
Mycobacterium leprae | Probable lipase LipE | 0.0043 | 0.0876 | 0.1859 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6065 | 0.6583 |
Brugia malayi | Fli-1 protein | 0.0265 | 0.8026 | 1 |
Schistosoma mansoni | netrin receptor unc5 | 0.0033 | 0.0552 | 0.0492 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0171 | 0.4971 | 0.4917 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0876 | 0.085 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0043 | 0.0876 | 0.0914 |
Brugia malayi | Protein kinase domain containing protein | 0.0034 | 0.0562 | 0.07 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1048 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0046 | 0.0959 | 0.3876 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0087 | 0.2292 | 0.2209 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0043 | 0.0876 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0107 | 0.0117 |
Brugia malayi | Ets-domain containing protein | 0.0087 | 0.2292 | 0.2856 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0595 | 0.0539 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0066 | 0.1587 | 0.4672 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0122 | 0.3398 | 0.3951 |
Mycobacterium tuberculosis | Conserved protein | 0.0025 | 0.0266 | 0.018 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0595 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0.0876 | 0.2579 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0087 | 0.2263 | 0.2584 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0171 | 0.4971 | 0.4917 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6065 | 0.6583 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | bZIP transcription factor family protein | 0.0171 | 0.4971 | 0.6194 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0087 | 0.2292 | 0.2209 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0081 | 0.21 | 0.6181 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0595 | 0.0742 |
Brugia malayi | hypothetical protein | 0.0134 | 0.3791 | 0.4724 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0081 | 0.21 | 0.2388 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.9158 | 1 |
Echinococcus granulosus | geminin | 0.0205 | 0.6065 | 0.6023 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0144 | 0.004 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0107 | 0.0133 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0144 | 0.0108 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.8421 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0211 | 0.0284 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.