Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | intermediate filament protein | 0.0142 | 0.3455 | 0.3455 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0122 | 0.2903 | 0.6167 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.2903 | 1 |
Schistosoma mansoni | smad | 0.0026 | 0.0262 | 0.0352 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0043 | 0.0726 | 0.1543 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.101 | 0.2145 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0262 | 0.0262 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0188 | 0.4707 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0352 | 0.0352 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0107 | 0.2493 | 0.8554 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0071 | 0.1501 | 0.5057 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0307 | 0.1436 |
Trypanosoma brucei | trypanothione reductase | 0.0042 | 0.0711 | 0.3866 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0647 | 0.1375 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0832 | 0.0832 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0122 | 0.2903 | 0.6167 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0647 | 0.3485 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0647 | 0.2043 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0352 | 0.1003 |
Echinococcus granulosus | lamin dm0 | 0.0142 | 0.3455 | 0.7341 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.004 | 0.0647 | 0.0647 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0068 | 0.0068 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0042 | 0.0711 | 0.3866 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0262 | 0.0352 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Brugia malayi | Muscleblind-like protein | 0.0171 | 0.4241 | 0.4241 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0647 | 0.1375 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0352 | 0.0473 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.008 | 0.173 | 0.252 |
Mycobacterium tuberculosis | Probable reductase | 0.0097 | 0.2197 | 0.7512 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0972 | 0.0972 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0026 | 0.0262 | 0.0557 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0352 | 0.0473 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.004 | 0.0647 | 0.3485 |
Echinococcus granulosus | dna polymerase eta | 0.004 | 0.0647 | 0.1375 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0972 | 0.0972 |
Plasmodium falciparum | glutathione reductase | 0.0042 | 0.0711 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0107 | 0.2493 | 0.8554 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0142 | 0.3455 | 0.3455 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0262 | 0.0262 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0352 | 0.0473 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.101 | 0.2145 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0262 | 0.0262 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.004 | 0.0647 | 0.0647 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.008 | 0.173 | 0.3675 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.008 | 0.173 | 0.5862 |
Loa Loa (eye worm) | glutathione reductase | 0.0042 | 0.0711 | 0.0711 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.101 | 0.1356 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0142 | 0.3455 | 0.3455 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.101 | 0.101 |
Echinococcus multilocularis | lamin | 0.0142 | 0.3455 | 0.7341 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4241 | 0.4241 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0097 | 0.2197 | 0.7512 |
Giardia lamblia | DINP protein human, muc B family | 0.004 | 0.0647 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0179 | 0.4469 | 0.6672 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.004 | 0.0647 | 0.2043 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0097 | 0.2197 | 0.702 |
Schistosoma mansoni | hypothetical protein | 0.0288 | 0.7448 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.008 | 0.173 | 0.252 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0352 | 0.0473 |
Toxoplasma gondii | thioredoxin reductase | 0.0042 | 0.0711 | 0.2267 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.008 | 0.173 | 0.5862 |
Echinococcus multilocularis | dna polymerase eta | 0.004 | 0.0647 | 0.1375 |
Schistosoma mansoni | lamin | 0.0142 | 0.3455 | 0.4639 |
Echinococcus multilocularis | musashi | 0.0142 | 0.3455 | 0.7341 |
Plasmodium vivax | glutathione reductase, putative | 0.0042 | 0.0711 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0647 | 0.2043 |
Echinococcus multilocularis | Smad4 | 0.0026 | 0.0262 | 0.0557 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0972 | 0.0972 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0972 | 0.0972 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0647 | 0.0878 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.101 | 0.101 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0076 | 0.1642 | 0.1642 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1363 | 0.1363 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0832 | 0.1768 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0068 | 0.5 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.101 | 0.2145 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0832 | 0.1117 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0352 | 0.4425 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0262 | 0.0262 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0352 | 0.0749 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0647 | 0.0878 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0307 | 0.1436 |
Schistosoma mansoni | lamin | 0.0142 | 0.3455 | 0.4639 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0026 | 0.0262 | 0.0352 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0647 | 0.1375 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.026 | 0.6663 | 0.6663 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0832 | 0.0832 |
Echinococcus granulosus | smad | 0.0026 | 0.0262 | 0.0557 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0042 | 0.0711 | 0.0711 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.2903 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0069 | 0.1435 | 0.3048 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0832 | 0.0832 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Onchocerca volvulus | 0.0142 | 0.3455 | 0.5577 | |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0832 | 0.1768 |
Schistosoma mansoni | DNA polymerase eta | 0.004 | 0.0647 | 0.0869 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Echinococcus multilocularis | smad | 0.0026 | 0.0262 | 0.0557 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0076 | 0.1642 | 0.1642 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.101 | 0.2145 |
Echinococcus granulosus | Smad4 | 0.0026 | 0.0262 | 0.0557 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.004 | 0.0647 | 0.0647 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0122 | 0.2903 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0068 | 0.0092 |
Echinococcus granulosus | lamin | 0.0142 | 0.3455 | 0.7341 |
Brugia malayi | Inositol-1 | 0.008 | 0.173 | 0.173 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.2903 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0832 | 0.0832 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0522 | 0.0701 |
Echinococcus granulosus | muscleblind protein | 0.0171 | 0.4241 | 0.9011 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.008 | 0.173 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0522 | 0.0522 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.008 | 0.173 | 0.5862 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.3384 | 0.3384 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.008 | 0.173 | 0.3675 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.004 | 0.0647 | 0.0869 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.004 | 0.0647 | 0.3485 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0097 | 0.2197 | 0.7512 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0307 | 0.1436 |
Schistosoma mansoni | intermediate filament proteins | 0.0142 | 0.3455 | 0.4639 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.004 | 0.0647 | 0.0869 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0069 | 0.1435 | 0.3048 |
Echinococcus granulosus | intermediate filament protein | 0.0142 | 0.3455 | 0.7341 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Brugia malayi | Thioredoxin reductase | 0.0042 | 0.0711 | 0.0711 |
Schistosoma mansoni | inositol monophosphatase | 0.008 | 0.173 | 0.2323 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.5144 | 0.5144 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0262 | 0.0352 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0262 | 0.0262 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0122 | 0.2903 | 1 |
Brugia malayi | Smad1 | 0.0026 | 0.0262 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0352 | 0.0352 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.3455 | 0.3455 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0122 | 0.2903 | 0.3897 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0832 | 0.1117 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0122 | 0.2903 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0068 | 0.0092 |
Onchocerca volvulus | 0.0142 | 0.3455 | 0.5577 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0122 | 0.2903 | 0.3897 |
Leishmania major | DNA polymerase eta, putative | 0.004 | 0.0647 | 0.2043 |
Leishmania major | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.2043 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0179 | 0.4469 | 0.6672 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0097 | 0.2197 | 0.7512 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0068 | 0.0145 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0042 | 0.0711 | 1 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0832 | 0.1768 |
Leishmania major | trypanothione reductase | 0.0042 | 0.0711 | 0.2267 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0188 | 0.4707 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.5144 | 0.5144 |
Loa Loa (eye worm) | inositol-1 | 0.008 | 0.173 | 0.173 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.017 | 0.4217 | 0.6946 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0647 | 0.3485 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.5916 | 0.8868 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0107 | 0.2493 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0142 | 0.3455 | 0.7341 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.008 | 0.173 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4241 | 0.4241 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0832 | 0.1768 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0097 | 0.2197 | 0.7512 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0647 | 0.3485 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0647 | 0.0647 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0026 | 0.0262 | 0.0557 |
Brugia malayi | intermediate filament protein | 0.0142 | 0.3455 | 0.3455 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0042 | 0.0711 | 0.2267 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0171 | 0.4241 | 0.9011 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0043 | 0.0726 | 0.1543 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0026 | 0.0262 | 0.0557 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0097 | 0.2197 | 0.7512 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0068 | 0.0068 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0647 | 0.3485 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.004 | 0.0647 | 0.3485 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0262 | 0.0262 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.017 | 0.4217 | 0.6291 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0262 | 0.0352 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.008 | 0.173 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0026 | 0.0262 | 0.0557 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0352 | 0.0749 |
Loa Loa (eye worm) | Smad1 | 0.0026 | 0.0262 | 0.0262 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0647 | 0.3485 |
Onchocerca volvulus | 0.0047 | 0.0832 | 0.0862 | |
Schistosoma mansoni | inositol monophosphatase | 0.008 | 0.173 | 0.2323 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0832 | 0.1117 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1363 | 0.1363 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0323 | 0.0686 |
Echinococcus multilocularis | muscleblind protein | 0.0171 | 0.4241 | 0.9011 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0832 | 0.0862 |
Plasmodium falciparum | thioredoxin reductase | 0.0042 | 0.0711 | 1 |
Brugia malayi | glutathione reductase | 0.0042 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0522 | 0.0522 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.026 | 0.6663 | 0.6663 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 0.6663 | 1 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0307 | 0.1436 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0307 | 0.1436 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0068 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1435 | 0.1435 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.008 | 0.173 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0647 | 0.1375 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.004 | 0.0647 | 0.2043 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.008 | 0.173 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.008 | 0.173 | 0.252 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.101 | 0.101 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.004 | 0.0647 | 0.2043 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0107 | 0.2493 | 0.8554 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0352 | 0.0749 |
Onchocerca volvulus | 0.0232 | 0.5916 | 1 | |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0262 | 0.0352 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.0129 ug ml-1 | Cytotoxicity against human SKBR3 cells after 2 days | ChEMBL. | 20542428 |
ED50 (functional) | = 0.022 ug ml-1 | Cytotoxicity against human HCT8 cells after 2 days | ChEMBL. | 20542428 |
ED50 (functional) | = 0.12 ug ml-1 | Cytotoxicity against human KB cells after 2 days | ChEMBL. | 20542428 |
ED50 (functional) | = 0.1243 ug ml-1 | Cytotoxicity against human DU145 cells after 2 days | ChEMBL. | 20542428 |
ED50 (functional) | = 0.1902 ug ml-1 | Cytotoxicity against human A549 cells after 2 days | ChEMBL. | 20542428 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.