Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.003 | 0.595 | 0.595 |
Brugia malayi | hypothetical protein | 0.0032 | 0.6346 | 0.6346 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0014 | 0.2128 | 0.2128 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.2128 | 0.2128 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.595 | 0.595 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0014 | 0.2128 | 0.2128 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.6346 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.2128 | 0.2128 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0044 | 0.9242 | 0.9242 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0032 | 0.6346 | 0.6346 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0014 | 0.2128 | 0.2128 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.6346 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0014 | 0.2128 | 0.2128 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0014 | 0.2128 | 0.2128 |
Echinococcus multilocularis | GPCR, family 2 | 0.0014 | 0.2128 | 0.2128 |
Echinococcus granulosus | GPCR family 2 | 0.0014 | 0.2128 | 0.2128 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0032 | 0.6346 | 0.6346 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0014 | 0.2128 | 0.2128 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.2128 | 0.2128 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0014 | 0.2128 | 0.2128 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.9242 | 0.9242 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.6346 | 0.6346 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.6346 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0032 | 0.6346 | 0.6346 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.003 | 0.595 | 0.595 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.6346 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0044 | 0.9242 | 0.9242 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.2128 | 0.2128 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.2128 | 0.2128 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0044 | 0.9242 | 0.9242 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.