Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.028 | 0.0033 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.4359 | 0.6103 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.1002 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.028 | 0.0309 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1138 | 0.0913 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1535 | 0.1321 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.028 | 0.0371 |
Plasmodium falciparum | glutathione reductase | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0977 | 0.135 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.046 | 0.0564 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0034 | 0.0729 | 0.374 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0464 | 0.0829 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.028 | 0.0392 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0464 | 0.0569 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.046 | 0.0218 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0028 | 0.0508 | 0.2022 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.046 | 0.0645 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.028 | 0.0309 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0052 | 0.1298 | 0.4028 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.028 | 0.0033 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1138 | 0.1522 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0028 | 0.0508 | 0.035 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.7134 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0252 | 0.7854 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0025 | 0.043 | 0.0521 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0707 | 0.0913 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.374 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.135 | 0.1131 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.028 | 0.0309 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.028 | 0.0309 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.028 | 0.0392 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.028 | 0.0371 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1535 | 0.2135 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0.0508 | 0.2022 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1535 | 0.4938 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.4359 | 0.6103 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0052 | 0.1298 | 0.4028 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.135 | 0.1131 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0508 | 0.0712 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0707 | 0.0991 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.028 | 0.0033 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0707 | 0.0971 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0115 | 0.3366 | 0.4673 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.1298 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0034 | 0.0729 | 0.1846 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0707 | 0.0471 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.028 | 0.0309 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.028 | 0.0371 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.028 | 0.0371 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0508 | 0.0631 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0707 | 0.0971 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0099 | 0.2856 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.028 | 0.0033 |
Toxoplasma gondii | thioredoxin reductase | 0.0099 | 0.2856 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.028 | 0.0033 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1535 | 0.17 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.028 | 0.0371 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0034 | 0.0729 | 0.064 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.199 | 0.2727 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.046 | 0.0624 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.028 | 0.0309 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0034 | 0.0729 | 0.4584 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0977 | 0.2339 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1535 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.3095 | 0.4339 |
Echinococcus multilocularis | protein dispatched 1 | 0.0056 | 0.1445 | 0.2008 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.135 | 0.1875 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0028 | 0.0508 | 0.0835 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0028 | 0.0508 | 0.0835 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0034 | 0.0729 | 0.1846 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.135 | 0.1875 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0252 | 0.7854 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.028 | 0.0309 |
Plasmodium falciparum | thioredoxin reductase | 0.0099 | 0.2856 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0034 | 0.0729 | 0.1846 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.01 | 0.2875 | 0.4017 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.046 | 0.0624 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0707 | 0.0971 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0049 | 0.1217 | 0.1687 |
Onchocerca volvulus | 0.0028 | 0.0508 | 0.2658 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0977 | 0.0748 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.028 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0444 | 0.0623 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.1298 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.028 | 0.0309 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0508 | 0.2022 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0464 | 0.065 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0508 | 0.2022 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.0494 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0034 | 0.0729 | 0.1846 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0977 | 0.135 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0052 | 0.1298 | 0.1802 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0977 | 0.2339 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.3095 | 0.429 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.028 | 0.0033 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.028 | 0.0033 |
Echinococcus multilocularis | lamin | 0.0026 | 0.046 | 0.0624 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.046 | 0.0645 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.028 | 0.0371 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0049 | 0.1217 | 0.1687 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0247 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0279 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.158 | 0.2215 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.199 | 0.2789 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.028 | 0.0309 |
Onchocerca volvulus | 0.0026 | 0.046 | 0.2104 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1217 | 0.1706 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0115 | 0.3366 | 0.4707 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0227 | 0.7025 | 0.8912 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0508 | 0.0631 |
Schistosoma mansoni | lamin | 0.0026 | 0.046 | 0.0218 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.028 | 0.0309 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.028 | 0.0033 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0028 | 0.0508 | 0.0835 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.1298 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0977 | 0.0748 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0034 | 0.0729 | 0.4584 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1535 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0707 | 0.0913 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.028 | 0.0371 |
Plasmodium falciparum | glutathione reductase | 0.0099 | 0.2856 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.028 | 0.0371 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0034 | 0.0729 | 0.1846 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.3095 | 0.429 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0464 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0247 | 0.0347 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.4359 | 0.6077 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0508 | 0.0712 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.028 | 0.0033 |
Schistosoma mansoni | lamin | 0.0026 | 0.046 | 0.0218 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.028 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0508 | 0.0712 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0049 | 0.1217 | 0.1706 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1159 | 0.0934 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1535 | 0.1321 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.046 | 0.0564 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.0279 | 0.012 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.028 | 0.0371 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0034 | 0.0729 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0115 | 0.3366 | 0.4707 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0099 | 0.2856 | 0.4003 |
Echinococcus multilocularis | protein patched | 0.0049 | 0.1217 | 0.1687 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.028 | 0.0371 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.028 | 0.0309 |
Brugia malayi | glutathione reductase | 0.0099 | 0.2856 | 0.3951 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.4359 | 0.6103 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.028 | 0.0392 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.046 | 0.0624 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.135 | 0.1875 |
Echinococcus granulosus | expressed conserved protein | 0.0108 | 0.3138 | 0.4386 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0117 | 0.3424 | 0.3257 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0707 | 0.0471 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0052 | 0.1298 | 0.1802 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.028 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1159 | 0.0934 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0707 | 0.0971 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.135 | 0.1823 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.028 | 0.0033 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1138 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.4359 | 0.6111 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0034 | 0.0729 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0028 | 0.0508 | 0.2022 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.7134 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.0279 | 0.0049 |
Mycobacterium tuberculosis | Probable reductase | 0.0227 | 0.7025 | 0.8912 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0508 | 0.0998 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0508 | 0.035 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0052 | 0.1298 | 0.4028 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.028 | 0.0371 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0052 | 0.1298 | 0.4028 |
Brugia malayi | CHE-14 protein | 0.0049 | 0.1217 | 0.1634 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0052 | 0.1298 | 0.1802 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.028 | 0.0371 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0227 | 0.7025 | 0.8912 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.028 | 0.0371 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0028 | 0.0508 | 0.2022 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0115 | 0.3366 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0977 | 0.2339 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.028 | 0.0033 |
Trypanosoma brucei | trypanothione reductase | 0.0099 | 0.2856 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.135 | 0.1893 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0052 | 0.1298 | 0.4028 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0158 | 0.0137 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1535 | 0.4938 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0508 | 0.0998 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.028 | 0.0309 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.028 | 0.0392 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.028 | 0.0309 |
Brugia malayi | Thioredoxin reductase | 0.0099 | 0.2856 | 0.3951 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.1298 | 0.1077 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0034 | 0.0729 | 0.1846 |
Plasmodium vivax | glutathione reductase, putative | 0.0099 | 0.2856 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0707 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.046 | 0.0645 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.028 | 0.0371 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0227 | 0.7025 | 0.8912 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0247 | 0.0325 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.028 | 0.0309 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0464 | 0.0829 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.7134 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.199 | 0.1787 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0977 | 0.1295 |
Leishmania major | trypanothione reductase | 0.0099 | 0.2856 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0025 | 0.043 | 0.0521 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.1846 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.135 | 0.1875 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0164 | 0.4982 | 0.6977 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0227 | 0.7025 | 0.8912 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.028 | 0.0392 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0227 | 0.7025 | 0.8912 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0279 | 0.0391 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0227 | 0.7025 | 0.8872 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.3366 | 0.4718 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.1298 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0252 | 0.7854 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.028 | 0.0309 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0052 | 0.1298 | 0.4028 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.0279 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.4359 | 0.6111 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.028 | 0.0309 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0034 | 0.0729 | 0.1846 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0164 | 0.4982 | 0.6977 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.1298 | 0.4028 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.028 | 0.0371 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0034 | 0.0729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.1217 | 0.9227 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0049 | 0.1217 | 0.1687 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.028 | 0.0033 |
Brugia malayi | MAP kinase sur-1 | 0.0052 | 0.1298 | 0.1749 |
Onchocerca volvulus | 0.0047 | 0.1138 | 1 | |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.1298 | 0.4028 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.028 | 0.0392 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.028 | 0.0309 |
Onchocerca volvulus | 0.0026 | 0.046 | 0.2104 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0279 | 0.0391 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.01 | 0.2875 | 0.4017 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0707 | 0.0971 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0247 | 0.0325 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0508 | 0.0998 |
Brugia malayi | hypothetical protein | 0.023 | 0.7134 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0034 | 0.0729 | 0.4584 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0034 | 0.0729 | 0.374 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.028 | 0.0392 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1535 | 0.2135 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1159 | 0.0934 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0707 | 0.0471 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0279 | 0.0391 |
Treponema pallidum | NADH oxidase | 0.0034 | 0.0729 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.028 | 0.0371 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0052 | 0.1298 | 0.1802 |
Echinococcus granulosus | lamin | 0.0026 | 0.046 | 0.0624 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0099 | 0.2856 | 0.3434 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.028 | 0.0392 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.028 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3095 | 0.4339 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0977 | 0.2339 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.028 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0707 | 0.0991 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0061 | 0.0086 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0016 | 0.0022 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.028 | 0.0309 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0707 | 0.0971 |
Echinococcus multilocularis | expressed conserved protein | 0.0108 | 0.3138 | 0.4386 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0247 | 0.0263 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0508 | 0.0631 |
Plasmodium falciparum | thioredoxin reductase | 0.0034 | 0.0729 | 0.1846 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0034 | 0.0729 | 0.1846 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.135 | 0.1131 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0052 | 0.1298 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0279 | 0.0391 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1159 | 0.0934 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0034 | 0.0729 | 0.0944 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0028 | 0.0508 | 0.2022 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0508 | 0.2022 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0252 | 0.7854 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0034 | 0.0729 | 0.1846 |
Echinococcus multilocularis | musashi | 0.0026 | 0.046 | 0.0624 |
Loa Loa (eye worm) | glutathione reductase | 0.0099 | 0.2856 | 0.4003 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0034 | 0.0729 | 0.1002 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0052 | 0.1298 | 0.182 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.1298 | 0.4028 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0021 | 0.0279 | 0.0242 |
Schistosoma mansoni | patched 1 | 0.0049 | 0.1217 | 0.0994 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.028 | 0.0033 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0099 | 0.2856 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.