Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.0189 | 0.2365 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0484 | 0.5942 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0051 | 0.0406 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0123 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0897 | 0.1565 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0458 | 0.5605 | 0.5595 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0387 | 0.1001 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.0325 | 0.0302 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0358 | 0.1113 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0724 | 0.2252 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0034 | 0.0189 | 0.0456 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0897 | 0.0876 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0123 | 0.0307 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0358 | 0.0599 |
Echinococcus granulosus | geminin | 0.0334 | 0.4017 | 0.7155 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.3213 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1667 | 0.4532 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.3213 | 0.8798 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0516 | 0.1357 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.0325 | 0.081 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0897 | 0.2233 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.007 | 0.2818 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.012 | 0.1376 |
Onchocerca volvulus | 0.0047 | 0.0358 | 0.1518 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.007 | 0.0129 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.007 | 0.0666 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0051 | 0.039 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0051 | 0.0086 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0897 | 0.2233 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.0189 | 0.2365 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0305 | 0.0759 |
Echinococcus granulosus | tar DNA binding protein | 0.0258 | 0.3056 | 0.5433 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0258 | 0.3056 | 0.9511 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.012 | 0.1376 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.3649 | 0.9084 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0688 | 0.1713 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0666 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.012 | 0.1376 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.1337 | 0.3621 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0268 | 0.0245 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0033 | 0.0176 | 0.0273 |
Brugia malayi | RNA binding protein | 0.0258 | 0.3056 | 0.9511 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.0325 | 0.1012 |
Mycobacterium leprae | conserved hypothetical protein | 0.0076 | 0.0724 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0123 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0688 | 0.6268 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.0897 | 0.2792 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0458 | 0.5605 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.0189 | 0.2365 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.012 | 0.5819 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0714 | 0.1776 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0688 | 0.1713 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.0325 | 0.0832 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0666 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0358 | 0.0599 |
Schistosoma mansoni | tar DNA-binding protein | 0.0258 | 0.3056 | 0.7608 |
Brugia malayi | hypothetical protein | 0.0025 | 0.007 | 0.0219 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0123 | 0.0384 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0201 | 0.0178 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.012 | 0.0097 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.3213 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.0897 | 0.2409 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0724 | 1 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0358 | 0.1113 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0268 | 0.0437 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0724 | 0.2194 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0441 | 0.1098 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0076 | 0.0724 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0454 | 0.1186 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0104 | 0.1084 | 0.1063 |
Onchocerca volvulus | 0.0076 | 0.0724 | 0.3888 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0201 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0123 | 0.0275 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0358 | 0.0335 |
Schistosoma mansoni | tar DNA-binding protein | 0.0258 | 0.3056 | 0.7608 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0441 | 0.1152 |
Trichomonas vaginalis | esterase, putative | 0.0076 | 0.0724 | 0.2194 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0724 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.007 | 0.0666 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0724 | 0.1801 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.012 | 0.0299 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.3213 | 0.8798 |
Echinococcus multilocularis | snurportin 1 | 0.0305 | 0.3649 | 0.3634 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0024 | 0.0074 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0051 | 0.039 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.0189 | 0.2365 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0441 | 0.0748 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0666 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0033 | 0.0176 | 0.0153 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0458 | 0.5605 | 0.5595 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0441 | 0.0419 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0104 | 0.1084 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0374 | 0.0965 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0724 | 0.1801 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.0962 | 0.168 |
Echinococcus granulosus | snurportin 1 | 0.0305 | 0.3649 | 0.6496 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0897 | 0.1565 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0186 | 0.213 | 0.2111 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.0189 | 0.2365 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0724 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.0325 | 0.0541 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0036 | 0.021 | 0.0654 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.012 | 0.0373 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0123 | 0.1427 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0201 | 0.0318 |
Loa Loa (eye worm) | beta-lactamase | 0.0076 | 0.0724 | 0.193 |
Loa Loa (eye worm) | RNA binding protein | 0.0258 | 0.3056 | 0.8364 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0123 | 0.01 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.0325 | 0.0541 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.007 | 0.2818 |
Schistosoma mansoni | ran | 0.0021 | 0.0024 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.4017 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0201 | 0.05 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0076 | 0.0724 | 0.2252 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0358 | 0.0891 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0441 | 0.1373 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0325 | 0.0832 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.1337 | 0.4159 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0441 | 0.0419 |
Toxoplasma gondii | ABC1 family protein | 0.0076 | 0.0724 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.007 | 0.0666 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0051 | 0.0086 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0051 | 0.0258 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.012 | 0.1376 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0106 | 0.1104 | 0.2749 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0149 | 0.1654 | 0.2921 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0048 | 0.0374 | 0.0351 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.0189 | 0.0297 |
Brugia malayi | Augmenter of liver regeneration | 0.0034 | 0.0189 | 0.0589 |
Onchocerca volvulus | 0.0076 | 0.0724 | 0.3888 | |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.0326 | 0.0812 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0724 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.0962 | 0.2992 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0033 | 0.0176 | 0.0438 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0688 | 0.6268 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.3213 | 0.7999 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.3213 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0441 | 0.0748 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.0325 | 0.0302 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0186 | 0.213 | 0.3774 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0189 | 0.2365 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.012 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0724 | 0.193 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0149 | 0.1654 | 0.1634 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0358 | 0.0922 |
Echinococcus multilocularis | geminin | 0.0334 | 0.4017 | 0.4003 |
Echinococcus multilocularis | expressed conserved protein | 0.0098 | 0.1003 | 0.0982 |
Schistosoma mansoni | tar DNA-binding protein | 0.0258 | 0.3056 | 0.7608 |
Schistosoma mansoni | tar DNA-binding protein | 0.0258 | 0.3056 | 0.7608 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0051 | 0.0086 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0048 | 0.0374 | 0.0627 |
Brugia malayi | beta-lactamase | 0.0076 | 0.0724 | 0.2252 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.0189 | 0.2365 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0688 | 0.1191 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.0792 | 0.2466 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0258 | 0.3056 | 0.8364 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0123 | 0.01 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.4017 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0123 | 0.0275 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0201 | 0.0625 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0123 | 0.0307 |
Loa Loa (eye worm) | glutamate receptor | 0.0039 | 0.0257 | 0.0645 |
Echinococcus granulosus | neuropeptide s receptor | 0.0458 | 0.5605 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0201 | 0.0489 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0076 | 0.0724 | 1 |
Onchocerca volvulus | 0.0076 | 0.0724 | 0.3888 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0258 | 0.3056 | 0.304 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.0189 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0076 | 0.0724 | 0.1254 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0358 | 0.0891 |
Loa Loa (eye worm) | TAR-binding protein | 0.0258 | 0.3056 | 0.8364 |
Onchocerca volvulus | 0.015 | 0.1667 | 1 | |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0123 | 0.1427 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0724 | 0.2194 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0305 | 0.0759 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0897 | 0.2233 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0724 | 0.2194 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.0189 | 0.0166 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0358 | 0.1518 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0688 | 0.6268 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0305 | 0.3649 | 1 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0123 | 0.0179 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0305 | 0.0759 |
Brugia malayi | hypothetical protein | 0.015 | 0.1667 | 0.5187 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.0189 | 0.2365 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0724 | 0.2194 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.012 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1084 | 0.2924 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0104 | 0.1084 | 0.1899 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0076 | 0.0724 | 0.193 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0724 | 0.2252 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0724 | 0.2194 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0039 | 0.0257 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0358 | 0.0922 |
Schistosoma mansoni | tar DNA-binding protein | 0.0258 | 0.3056 | 0.7608 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0688 | 0.2142 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0104 | 0.1084 | 0.3373 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.1337 | 0.3621 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0358 | 0.0891 |
Mycobacterium leprae | Probable lipase LipE | 0.0076 | 0.0724 | 0.5 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0358 | 0.0335 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0688 | 0.6268 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.0962 | 0.094 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0123 | 0.6034 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0897 | 0.0876 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0688 | 0.0666 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0123 | 0.0384 |
Brugia malayi | TAR-binding protein | 0.0258 | 0.3056 | 0.9511 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0325 | 0.0946 |
Schistosoma mansoni | ran | 0.0021 | 0.0024 | 0.0059 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0123 | 0.0179 |
Echinococcus granulosus | expressed conserved protein | 0.0098 | 0.1003 | 0.1755 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0441 | 0.1152 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0305 | 0.0759 |
Schistosoma mansoni | hypothetical protein | 0.0287 | 0.3419 | 0.851 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 99 % | Antitubercular activity against Mycobacterium tuberculosis H37Rv at MIC after 24 hrs by broth microdilution method | ChEMBL. | 20034708 |
IZ (functional) | = 21 mm | Antimicrobial activity against Escherichia coli ATTC 25923 at MIC after 3 to 4 days by disc diffusion method | ChEMBL. | 20034708 |
MIC (functional) | = 1 ug ml-1 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 24 hrs by broth microdilution method | ChEMBL. | 20034708 |
MIC (functional) | = 6.25 ug ml-1 | Antimicrobial activity against Escherichia coli ATTC 25923 after 16 to 18 hrs by serial dilution method | ChEMBL. | 20034708 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.