Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.3249 | 0.2673 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0045 | 0.4388 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.4388 | 0.3199 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.9213 | 0.9413 |
Echinococcus granulosus | dna polymerase eta | 0.0075 | 0.9788 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.4388 | 0.3199 |
Leishmania major | DNA polymerase eta, putative | 0.0075 | 0.9788 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0351 | 0.0359 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0045 | 0.4388 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.0045 | 0.4388 | 0.4277 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Echinococcus multilocularis | dna polymerase kappa | 0.0045 | 0.4388 | 0.4277 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.043 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0045 | 0.4388 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.043 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3262 | 0.3333 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0045 | 0.4388 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0045 | 0.4388 | 0.4483 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0045 | 0.4388 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0075 | 0.9788 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Giardia lamblia | DINP protein human, muc B family | 0.0045 | 0.4388 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7186 | 0.7243 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0045 | 0.4388 | 0.4483 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0045 | 0.4388 | 0.043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0045 | 0.4388 | 0.4483 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0045 | 0.4388 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4049 | 0.4137 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.043 |
Echinococcus multilocularis | dna polymerase eta | 0.0075 | 0.9788 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.9788 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0044 | 0.4145 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.7844 | 0.8014 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.043 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0075 | 0.9788 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.3698 | 0.3778 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.2814 | 0.261 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0045 | 0.4388 | 0.4277 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0075 | 0.9788 | 0.977 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0075 | 0.9788 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.4388 | 0.3908 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.4388 | 0.3199 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.4388 | 0.3199 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7186 | 0.7243 |
Trypanosoma brucei | unspecified product | 0.0045 | 0.4388 | 0.3199 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.2814 | 0.261 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0045 | 0.4388 | 0.5 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0045 | 0.4388 | 0.4277 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.