Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | Janus kinase 2 | Starlite/ChEMBL | References |
Homo sapiens | Janus kinase 3 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0044 | 0.0942 | 0.4222 |
Plasmodium vivax | pyruvate kinase, putative | 0.0034 | 0.0691 | 0.6463 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0025 | 0.0444 | 0.299 |
Entamoeba histolytica | Flap nuclease, putative | 0.0025 | 0.0444 | 0.1529 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0739 | 0.0739 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Schistosoma mansoni | tyrosinase precursor | 0.019 | 0.4936 | 0.4936 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0026 | 0.0026 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0739 | 0.2499 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.2738 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1106 | 0.2241 |
Schistosoma mansoni | ap endonuclease | 0.0044 | 0.0942 | 0.0942 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.2738 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0026 | 0.0052 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.1623 | 1 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0026 | 0.0026 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1164 | 0.1164 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0044 | 0.0942 | 0.5 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0691 | 0.4955 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0691 | 0.14 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0691 | 0.14 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.1164 | 0.1164 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0026 | 0.0026 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.2738 | 1 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0025 | 0.0444 | 0.299 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0026 | 0.0052 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0026 | 0.0026 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.1623 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0025 | 0.0444 | 0.0444 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.1164 | 0.1164 |
Echinococcus multilocularis | tumor protein p63 | 0.0339 | 0.9027 | 0.9027 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0044 | 0.0942 | 1 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0026 | 0.0026 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0044 | 0.0942 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0044 | 0.0942 | 0.3367 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0739 | 0.1497 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0026 | 0.0026 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0691 | 0.1355 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0026 | 0.0026 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.0378 | 0.0378 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0691 | 0.1355 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0026 | 0.0052 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.1106 | 0.1106 |
Brugia malayi | SH2 domain containing protein | 0.001 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0026 | 0.0026 |
Brugia malayi | hypothetical protein | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0031 | 0.0062 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.1623 | 0.1623 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0739 | 0.5919 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0691 | 0.14 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.2738 | 0.2738 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0026 | 0.0052 |
Echinococcus granulosus | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0181 | 0.0367 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0044 | 0.0942 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0026 | 0.0052 |
Onchocerca volvulus | 0.019 | 0.4936 | 1 | |
Onchocerca volvulus | 0.005 | 0.1106 | 0.2201 | |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0044 | 0.0942 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.1164 | 0.2358 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | SRC-1 | 0.001 | 0.0031 | 0.0062 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0026 | 0.0026 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0181 | 0.0181 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0739 | 0.5919 |
Echinococcus multilocularis | pyruvate kinase | 0.0027 | 0.0492 | 0.0492 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0181 | 0.0181 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1117 | 0.2263 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1117 | 0.2263 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0026 | 0.0026 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.1623 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0069 | 0.1623 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0044 | 0.0942 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0684 | 0.0684 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0691 | 0.2092 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Echinococcus granulosus | c src tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0026 | 0.0026 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0691 | 0.2092 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0691 | 0.2092 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0026 | 0.0052 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.001 | 0.0031 | 0.0031 |
Toxoplasma gondii | exonuclease III APE | 0.0044 | 0.0942 | 1 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0691 | 0.14 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0024 | 0.0406 | 0.0822 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0026 | 0.0026 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0181 | 0.0181 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.3444 | 0.6977 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | protein-tyrosine kinase | 0.001 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | tyrosinase 1 | 0.019 | 0.4936 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.019 | 0.4936 | 1 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.001 | 0.0031 | 0.0031 |
Plasmodium falciparum | pyruvate kinase | 0.0034 | 0.0691 | 0.6463 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0034 | 0.0691 | 0.2092 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0026 | 0.0052 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0739 | 0.5919 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0026 | 0.0026 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0044 | 0.0942 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0026 | 0.0052 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0044 | 0.0942 | 0.0942 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0181 | 0.0181 |
Echinococcus multilocularis | c src tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0025 | 0.0444 | 0.09 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0181 | 0.0181 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0026 | 0.0026 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0684 | 0.1386 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.1623 | 0.3289 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0181 | 0.0181 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0034 | 0.0691 | 0.14 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.001 | 0.0031 | 0.0062 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0109 | 0.2738 | 0.2738 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0024 | 0.0406 | 0.1386 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0031 | 0.0062 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.1164 | 0.2358 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0034 | 0.0691 | 0.6463 |
Echinococcus granulosus | tumor protein p63 | 0.0339 | 0.9027 | 0.9027 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0026 | 0.0052 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0031 | 0.0062 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0026 | 0.0052 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0739 | 0.0739 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0044 | 0.0942 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1164 | 0.1164 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0026 | 0.0026 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0034 | 0.0691 | 0.1819 |
Brugia malayi | SRC-1 | 0.001 | 0.0031 | 0.0062 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0044 | 0.0942 | 0.4222 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.004 | 0.0834 | 0.0834 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0739 | 0.0739 |
Onchocerca volvulus | 0.019 | 0.4936 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0181 | 0.0181 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | tyrosinase precursor | 0.019 | 0.4936 | 0.4936 |
Loa Loa (eye worm) | TK protein kinase | 0.001 | 0.0031 | 0.0062 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0739 | 0.1497 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0739 | 0.7139 |
Chlamydia trachomatis | pyruvate kinase | 0.0034 | 0.0691 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0031 | 0.0062 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0034 | 0.0691 | 0.2092 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0691 | 0.1355 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0181 | 0.0367 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1117 | 0.2263 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0034 | 0.0691 | 0.14 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.019 | 0.4936 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0181 | 0.0367 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0026 | 0.0052 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.1623 | 0.1623 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0026 | 0.0052 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0406 | 0.0822 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.1164 | 0.1164 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0026 | 0.0052 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.001 | 0.0031 | 0.0031 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0739 | 0.2617 |
Echinococcus granulosus | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Plasmodium falciparum | flap endonuclease 1 | 0.0025 | 0.0444 | 0.299 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | Flap endonuclease-1 | 0.0025 | 0.0444 | 0.09 |
Giardia lamblia | Pyruvate kinase | 0.0034 | 0.0691 | 0.6463 |
Brugia malayi | SH2 domain containing protein | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.1623 | 0.3289 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0026 | 0.0052 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0044 | 0.0942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0062 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0739 | 0.0739 |
Schistosoma mansoni | ap endonuclease | 0.0044 | 0.0942 | 0.0942 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1164 | 0.1164 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.2738 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.001 | 0.0033 | 0.0068 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.4936 | 1 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.1164 | 0.1164 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0181 | 0.0367 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0181 | 0.0181 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0044 | 0.0942 | 0.4222 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.1623 | 0.5882 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0691 | 0.2092 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1117 | 0.2263 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.4936 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0739 | 0.2499 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0026 | 0.0026 |
Onchocerca volvulus | 0.019 | 0.4936 | 1 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0109 | 0.2738 | 0.2738 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0739 | 0.1912 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.019 | 0.4936 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.019 | 0.4936 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Brugia malayi | ShTK domain containing protein | 0.019 | 0.4936 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.019 | 0.4936 | 1 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0691 | 0.0691 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0044 | 0.0942 | 0.1909 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0026 | 0.0052 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.3444 | 0.6977 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.1623 | 0.1623 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0026 | 0.0026 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0181 | 0.0181 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0691 | 0.4955 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0026 | 0.0026 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0739 | 0.2499 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0026 | 0.0052 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0109 | 0.2738 | 0.2738 |
Echinococcus granulosus | flap endonuclease 1 | 0.0025 | 0.0444 | 0.0444 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0181 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0109 | 0.2738 | 0.5547 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0044 | 0.0942 | 0.4222 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | tyrosine kinase | 0.001 | 0.0031 | 0.0031 |
Onchocerca volvulus | 0.019 | 0.4936 | 1 | |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.019 | 0.4936 | 1 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0025 | 0.0444 | 0.299 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.3444 | 0.6977 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0684 | 0.1386 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0044 | 0.0942 | 0.0942 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.001 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.001 | 0.0031 | 0.0062 |
Schistosoma mansoni | pyruvate kinase | 0.0018 | 0.0232 | 0.0232 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.019 | 0.4936 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0044 | 0.0942 | 0.1909 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0026 | 0.0026 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0034 | 0.0691 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.004 | 0.0834 | 0.0834 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0026 | 0.0026 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0739 | 0.2499 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.