Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.1736 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.1736 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0795 | 0.0739 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.1736 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0795 | 0.0679 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7315 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.046 | 0.0242 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.1736 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.1736 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4323 | 0.4395 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.3987 | 0.4014 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3572 | 0.3541 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.9249 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3144 | 0.4076 |
Brugia malayi | hypothetical protein | 0.0029 | 0.1736 | 0.1736 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.121 | 0.121 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.1736 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.1736 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.1736 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3144 | 0.4076 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.7944 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1736 | 0.1452 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0795 | 0.0739 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.356 | 0.356 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.