Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0115 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0201 | 0.0718 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0035 | 0.0194 | 0.0194 |
Brugia malayi | RNA binding protein | 0.0261 | 0.2649 | 0.9456 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0111 | 0.1019 | 0.4335 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0214 | 0.0764 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0344 | 0.3322 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0042 | 0.0273 | 0.0974 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0194 | 0.0691 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.006 | 0.0466 | 0.1543 |
Brugia malayi | jmjC domain containing protein | 0.0042 | 0.0273 | 0.0974 |
Trypanosoma brucei | polo-like protein kinase | 0.0113 | 0.1036 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0111 | 0.1019 | 0.8708 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.006 | 0.0466 | 0.3808 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0123 | 0.1153 | 0.4906 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0344 | 0.1229 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0194 | 0.4156 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0115 | 0.0411 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0214 | 0.091 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0115 | 0.1111 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0344 | 0.1464 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.2004 | 0.7155 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0113 | 0.1036 | 1 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0214 | 0.0764 |
Brugia malayi | jmjC domain containing protein | 0.0114 | 0.105 | 0.3747 |
Onchocerca volvulus | Alhambra homolog | 0.0035 | 0.0194 | 0.0852 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0109 | 0.1053 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0214 | 0.0764 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0109 | 0.2342 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.1132 | 0.3957 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0214 | 0.0631 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0115 | 0.0411 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0214 | 0.0764 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0214 | 0.0764 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0214 | 0.0764 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0113 | 0.1036 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0201 | 0.0718 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0111 | 0.1019 | 0.4335 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0344 | 0.3322 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.006 | 0.0466 | 0.4496 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.006 | 0.0466 | 0.1759 |
Loa Loa (eye worm) | glutaminase | 0.0275 | 0.2801 | 1 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0194 | 0.0194 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.0869 | 0.3282 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0622 | 0.5507 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0201 | 0.0718 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0201 | 0.076 |
Toxoplasma gondii | exonuclease III APE | 0.006 | 0.0466 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.006 | 0.0466 | 0.1663 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.006 | 0.0466 | 0.0466 |
Giardia lamblia | Kinase, PLK | 0.0113 | 0.1036 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0622 | 0.5507 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0109 | 0.1053 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0214 | 0.2065 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0123 | 0.1153 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0042 | 0.0273 | 0.0273 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0646 | 0.2308 |
Schistosoma mansoni | glutaminase | 0.0275 | 0.2801 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0622 | 0.5507 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0194 | 0.4156 |
Schistosoma mansoni | jumonji domain containing protein | 0.009 | 0.0796 | 0.2843 |
Echinococcus granulosus | jumonji domain containing protein | 0.0048 | 0.0341 | 0.1287 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0214 | 0.091 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0042 | 0.0273 | 0.0974 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0113 | 0.1036 | 0.3913 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0109 | 0.0251 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.2649 | 0.9456 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0028 | 0.0118 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.0869 | 0.0869 |
Echinococcus multilocularis | tar DNA binding protein | 0.0261 | 0.2649 | 0.2649 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0214 | 0.2065 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0869 | 0.3104 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0214 | 0.091 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.006 | 0.0466 | 0.1663 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.0466 | 0.1663 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0214 | 0.0764 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0462 | 0.153 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0421 | 0.1502 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.006 | 0.0466 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0115 | 0.0411 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.006 | 0.0466 | 0.1981 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0344 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0115 | 0.0273 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.006 | 0.0466 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0214 | 0.0764 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0115 | 0.0411 |
Onchocerca volvulus | 0.0037 | 0.0214 | 0.1073 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0115 | 0.0411 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0048 | 0.0341 | 0.0341 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.2649 | 0.9456 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0214 | 0.0764 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0344 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.103 | 0.3587 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0214 | 0.2065 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0201 | 0.0201 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0194 | 0.0691 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0214 | 0.0764 |
Brugia malayi | PHD-finger family protein | 0.0035 | 0.0194 | 0.0691 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0214 | 0.0808 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0035 | 0.0194 | 0.0691 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0113 | 0.1036 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0194 | 0.0557 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0072 | 0.0594 | 0.2008 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.006 | 0.0466 | 0.4496 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0028 | 0.0118 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0201 | 0.0718 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0112 | 0.103 | 0.3678 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.004 | 0.0856 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0214 | 0.091 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0109 | 0.2342 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0114 | 0.105 | 0.3963 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.0466 | 0.4496 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0344 | 0.739 |
Onchocerca volvulus | 0.0037 | 0.0214 | 0.1073 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0214 | 0.091 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0214 | 0.4594 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.0466 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0109 | 0.2342 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.004 | 0.017 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0214 | 0.4594 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0115 | 0.0411 |
Plasmodium falciparum | phd finger protein, putative | 0.0035 | 0.0194 | 0.4156 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0111 | 0.1019 | 0.4335 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0214 | 0.0764 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0113 | 0.1036 | 0.37 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0123 | 0.1153 | 0.4906 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0115 | 0.0411 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0112 | 0.103 | 0.3587 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0622 | 0.2222 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0261 | 0.2649 | 0.9448 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0344 | 0.3322 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0214 | 0.0764 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.1132 | 0.4043 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0622 | 0.235 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0869 | 0.3104 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.0869 | 0.3104 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0113 | 0.1036 | 0.1036 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0115 | 0.0411 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0115 | 0.0411 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0113 | 0.1036 | 0.37 |
Giardia lamblia | PHD finger protein 15 | 0.0035 | 0.0194 | 0.1868 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0214 | 0.0952 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0035 | 0.0194 | 0.0557 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0214 | 0.0631 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0214 | 0.091 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0214 | 0.2065 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.0466 | 0.1663 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0646 | 0.2197 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0042 | 0.0273 | 0.0844 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0115 | 0.0273 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0261 | 0.2649 | 0.9456 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0021 | 0.004 | 0.0142 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0115 | 0.1111 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0201 | 0.0584 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0115 | 0.0411 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0112 | 0.103 | 0.3678 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0113 | 0.1036 | 0.3609 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0113 | 0.1036 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0275 | 0.2801 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0344 | 0.1229 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0113 | 0.1036 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0275 | 0.2801 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0214 | 0.0764 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0622 | 0.0622 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0123 | 0.1153 | 0.4906 |
Brugia malayi | TAR-binding protein | 0.0261 | 0.2649 | 0.9456 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0114 | 0.105 | 0.105 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0111 | 0.1019 | 0.4335 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0109 | 0.1053 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0622 | 0.2222 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0214 | 0.091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.2649 | 0.9456 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0021 | 0.004 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0344 | 0.739 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0869 | 0.3104 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0109 | 0.0389 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.2649 | 0.9456 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0344 | 0.739 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0344 | 0.13 |
Loa Loa (eye worm) | RNA binding protein | 0.0261 | 0.2649 | 0.9448 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.004 | 0.0856 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0006 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0201 | 0.0584 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0344 | 0.0344 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.2004 | 0.7155 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0344 | 0.739 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0113 | 0.1036 | 0.37 |
Echinococcus multilocularis | geminin | 0.0202 | 0.2004 | 0.2004 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0109 | 0.1053 |
Mycobacterium tuberculosis | Probable reductase | 0.0111 | 0.1019 | 0.4335 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0421 | 0.1502 |
Onchocerca volvulus | 0.0037 | 0.0214 | 0.1073 | |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0214 | 0.0764 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0622 | 0.5507 |
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0201 | 0.076 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0214 | 0.0631 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0201 | 0.076 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.0466 | 0.4496 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.0869 | 0.3282 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0194 | 0.0731 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0214 | 0.0952 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0115 | 0.049 |
Echinococcus granulosus | geminin | 0.0202 | 0.2004 | 0.7566 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0214 | 0.091 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0214 | 0.091 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0035 | 0.0194 | 0.0731 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0115 | 0.0273 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.1132 | 0.3957 |
Echinococcus granulosus | tar DNA binding protein | 0.0261 | 0.2649 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0275 | 0.2801 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0028 | 0.0118 |
Trichomonas vaginalis | glutaminase, putative | 0.0275 | 0.2801 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0261 | 0.2649 | 0.9448 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0194 | 0.4156 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0201 | 0.0718 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0115 | 0.049 |
Schistosoma mansoni | kinase | 0.0057 | 0.0437 | 0.156 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0109 | 0.2342 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.0869 | 0.3004 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.0466 | 0.1663 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0201 | 0.0201 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0214 | 0.0764 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0042 | 0.0273 | 0.103 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0344 | 0.739 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.2351 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.0466 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0115 | 0.1111 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.0869 | 0.0869 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0077 | 0.0646 | 0.2308 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.0466 | 0.1663 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0214 | 0.0764 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0111 | 0.1019 | 0.4335 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0214 | 0.091 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0028 | 0.0118 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0201 | 0.0718 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.2649 | 0.9456 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.006 | 0.0466 | 0.4496 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0214 | 0.0214 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0214 | 0.0764 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0622 | 0.2222 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Induction of CFP-tagged glucocorticoid receptor nuclear localization expressed in BAEC at 0.01 to 1 uM after 1 hr by luminescence assay | ChEMBL. | 20308375 | |
MBC (functional) | = 1.5 ug ml-1 | Bactericidal activity against Escherichia coli ATCC 25922 with lipid composition of 85% phosphatidylethanolamine, 15% phosphatidylglycerol and 5% cardiolipin by broth microdilution method | ChEMBL. | 20585129 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.