Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0473 | 0.0418 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.0319 | 0.0943 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.1252 | 0.315 |
Echinococcus granulosus | snurportin 1 | 0.0327 | 0.3839 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0329 | 0.1363 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0329 | 0.0273 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.002 | 0.0084 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0337 | 0.0725 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0057 | 0.0537 | 0.1778 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0138 | 0.049 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0058 | 0.0025 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0101 | 0.1074 | 0.8958 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.1252 | 0.315 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0138 | 0.2951 |
Schistosoma mansoni | lamin | 0.0057 | 0.0537 | 0.1268 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0109 | 0.1169 | 0.1118 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0116 | 0.0385 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0063 | 0.0043 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0337 | 0.0281 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.002 | 0.0084 | 0.013 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 0.107 | 0.1019 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.002 | 0.0084 | 0.0637 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.0466 | 0.3679 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0351 | 0.0776 |
Brugia malayi | Importin beta-1 subunit | 0.0031 | 0.0215 | 0.0713 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0063 | 0.1976 |
Echinococcus multilocularis | GPCR, family 2 | 0.0052 | 0.0473 | 0.0418 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.002 | 0.0084 | 0.0637 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.002 | 0.0084 | 0.013 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.013 | 0.1427 | 0.4836 |
Treponema pallidum | DNA ligase (lig) | 0.002 | 0.0084 | 1 |
Echinococcus granulosus | nibrin | 0.002 | 0.0084 | 0.0069 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0473 | 0.11 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0041 | 0.0337 | 0.1115 |
Trichomonas vaginalis | ran, putative | 0.0023 | 0.0116 | 0.0295 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0329 | 0.2447 |
Giardia lamblia | Replication factor C, subunit 1 | 0.002 | 0.0084 | 0.0234 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.0466 | 0.1081 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0144 | 0.1604 | 0.4089 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.002 | 0.0084 | 0.0000031493 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0138 | 0.0306 |
Brugia malayi | hypothetical protein | 0.011 | 0.1189 | 0.394 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0138 | 0.0722 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0337 | 0.2511 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.3019 | 0.7833 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0473 | 0.11 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0319 | 0.1311 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0116 | 0.053 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.037 | 0.0827 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0117 | 0.1268 | 0.4277 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0138 | 0.2951 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0138 | 0.0306 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.0319 | 0.9619 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.0466 | 0.1069 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.0278 | 0.1449 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0319 | 0.1057 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0138 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1208 | 0.3032 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.107 | 0.2679 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0031 | 0.0215 | 0.3858 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.0466 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.002 | 0.0084 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0537 | 0.1256 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0337 | 0.1398 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0138 | 0.2951 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.0466 | 0.1069 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0144 | 0.0435 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0063 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1074 | 0.2679 |
Echinococcus granulosus | tar DNA binding protein | 0.026 | 0.3019 | 0.7833 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0144 | 0.0435 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0337 | 0.0281 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0138 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.025 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0215 | 0.0404 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 0.107 | 0.2679 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0524 | 0.1222 |
Echinococcus multilocularis | expressed conserved protein | 0.0095 | 0.0999 | 0.0947 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0138 | 0.2951 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0138 | 0.0199 |
Schistosoma mansoni | lamin | 0.0057 | 0.0537 | 0.1268 |
Echinococcus multilocularis | lamin | 0.0057 | 0.0537 | 0.0482 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0023 | 0.0116 | 0.0059 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.037 | 0.0314 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.0319 | 0.6397 |
Chlamydia trachomatis | DNA ligase | 0.002 | 0.0084 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0117 | 0.1268 | 0.4277 |
Schistosoma mansoni | topbp1 | 0.002 | 0.0084 | 0.0069 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.1189 | 0.1138 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0473 | 0.0418 |
Brugia malayi | hypothetical protein | 0.002 | 0.0084 | 0.0277 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.3019 | 0.7833 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0319 | 0.0943 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0101 | 0.107 | 0.3545 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0101 | 0.1074 | 0.2689 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0164 | 0.184 | 0.4708 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0327 | 0.3839 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.3019 | 0.7833 |
Brugia malayi | TAR-binding protein | 0.026 | 0.3019 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0138 | 0.049 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.026 | 0.3019 | 0.783 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0116 | 0.0142 |
Brugia malayi | RNA recognition motif domain containing protein | 0.026 | 0.3019 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0473 | 0.11 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.002 | 0.0084 | 0.0234 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0117 | 0.1268 | 0.4277 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.0319 | 0.0943 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0023 | 0.0116 | 0.1439 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.002 | 0.0084 | 0.0234 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0109 | 0.1169 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0138 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0109 | 0.1169 | 0.9812 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 0.107 | 0.1019 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0112 | 0.1208 | 0.4 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.0319 | 0.0943 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0489 | 0.1129 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.184 | 0.4708 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.002 | 0.0084 | 0.0069 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0138 | 0.0722 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.0319 | 0.9619 |
Entamoeba histolytica | Ran family GTPase | 0.0023 | 0.0116 | 0.0297 |
Brugia malayi | hypothetical protein | 0.002 | 0.0084 | 0.0277 |
Loa Loa (eye worm) | RNA binding protein | 0.026 | 0.3019 | 0.783 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0319 | 0.0943 |
Onchocerca volvulus | 0.0039 | 0.0319 | 0.217 | |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0214 | 0.04 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0041 | 0.0337 | 0.2287 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0351 | 0.0776 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0117 | 0.1268 | 0.4277 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0109 | 0.1169 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.002 | 0.0084 | 0.0026 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0329 | 0.6651 |
Toxoplasma gondii | ATPase, AAA family protein | 0.002 | 0.0084 | 0.0637 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.3019 | 0.7833 |
Loa Loa (eye worm) | TAR-binding protein | 0.026 | 0.3019 | 0.783 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0031 | 0.0215 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.2115 | 0.5436 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.0466 | 0.1461 |
Echinococcus granulosus | replication factor c subunit 1 | 0.002 | 0.0084 | 0.0069 |
Brugia malayi | Inositol-1 | 0.004 | 0.0329 | 0.1091 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.0319 | 0.0943 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0109 | 0.1169 | 0.2938 |
Onchocerca volvulus | 0.0057 | 0.0537 | 0.4177 | |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0116 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0164 | 0.0268 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.037 | 0.0814 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0329 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.3019 | 0.7833 |
Plasmodium falciparum | importin beta, putative | 0.0031 | 0.0215 | 0.3858 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0103 | 0.1093 | 0.2739 |
Schistosoma mansoni | intermediate filament proteins | 0.0057 | 0.0537 | 0.1268 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0101 | 0.1074 | 0.3558 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0177 | 0.0302 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.107 | 0.2679 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0084 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0181 | 0.2053 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0117 | 0.1268 | 0.4277 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0138 | 0.2951 |
Plasmodium vivax | importin-beta 2, putative | 0.0031 | 0.0215 | 0.3858 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.0319 | 0.0943 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.002 | 0.0084 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.037 | 0.0814 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0215 | 0.1419 |
Brugia malayi | intermediate filament protein | 0.0057 | 0.0537 | 0.1778 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0319 | 0.1311 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0101 | 0.107 | 0.2669 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.0466 | 1 |
Echinococcus granulosus | geminin | 0.0174 | 0.1964 | 0.5041 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0041 | 0.0337 | 0.0738 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0144 | 0.1604 | 0.1555 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0109 | 0.1169 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.0319 | 0.1057 |
Echinococcus multilocularis | lamin dm0 | 0.0057 | 0.0537 | 0.0482 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Echinococcus granulosus | intermediate filament protein | 0.0057 | 0.0537 | 0.1268 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0329 | 0.2447 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.0319 | 0.1753 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0138 | 0.2951 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.0319 | 0.0679 |
Brugia malayi | DKFZp564C0469 protein | 0.002 | 0.0084 | 0.0277 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0329 | 0.1363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0084 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.1252 | 0.4147 |
Onchocerca volvulus | 0.0057 | 0.0537 | 0.4177 | |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0023 | 0.0116 | 0.1439 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.0466 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0164 | 0.184 | 0.6095 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0138 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0164 | 0.0268 |
Schistosoma mansoni | DNA ligase IV | 0.002 | 0.0084 | 0.0069 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0319 | 0.1311 |
Giardia lamblia | Kinase, PLK | 0.0109 | 0.1169 | 1 |
Leishmania major | trypanothione reductase | 0.0051 | 0.0466 | 0.3679 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.107 | 0.2679 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0329 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0473 | 0.1088 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.0466 | 0.0411 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0063 | 0.0126 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.0319 | 0.1311 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0138 | 0.0199 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0319 | 0.2354 |
Brugia malayi | RNA binding protein | 0.026 | 0.3019 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0329 | 0.0719 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.0319 | 0.0679 |
Echinococcus granulosus | lamin dm0 | 0.0057 | 0.0537 | 0.1268 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1964 | 0.5041 |
Onchocerca volvulus | 0.0039 | 0.0319 | 0.217 | |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.1189 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0055 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0109 | 0.1169 | 1 |
Echinococcus multilocularis | geminin | 0.0174 | 0.1964 | 0.1917 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0116 | 0.053 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0023 | 0.0116 | 0.0156 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0445 | 0.039 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0084 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.0466 | 0.1545 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0319 | 0.0692 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.013 | 0.1427 | 0.4836 |
Brugia malayi | beta-lactamase | 0.0039 | 0.0319 | 0.1057 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.1189 | 0.2994 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0214 | 0.0708 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0337 | 0.1398 |
Echinococcus multilocularis | nibrin | 0.002 | 0.0084 | 0.0026 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0052 | 0.0473 | 0.1568 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0041 | 0.0337 | 0.2511 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0319 | 0.9619 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0329 | 0.2447 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0337 | 0.2511 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.0319 | 0.0943 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0329 | 0.0719 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0138 | 0.0403 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.1189 | 0.2994 |
Schistosoma mansoni | ran | 0.0023 | 0.0116 | 0.0156 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0116 | 0.1439 |
Echinococcus multilocularis | musashi | 0.0057 | 0.0537 | 0.0482 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.0319 | 0.0263 |
Schistosoma mansoni | importin beta-1 | 0.0031 | 0.0215 | 0.0417 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.0319 | 0.9619 |
Leishmania major | GTP-binding protein, putative | 0.0023 | 0.0116 | 0.053 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.002 | 0.0084 | 0.0234 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0054 | 0.0498 | 0.2208 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 0.107 | 0.2679 |
Schistosoma mansoni | ran | 0.0023 | 0.0116 | 0.0156 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.013 | 0.1427 | 0.4836 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.037 | 0.1226 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0117 | 0.1268 | 0.8815 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.1208 | 0.3042 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0319 | 0.2354 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.0466 | 0.3679 |
Echinococcus multilocularis | snurportin 1 | 0.0327 | 0.3839 | 0.3803 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0109 | 0.1169 | 0.3871 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0473 | 0.11 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0329 | 1 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0337 | 0.0738 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0109 | 0.1169 | 0.2938 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0319 | 0.2354 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0057 | 0.0537 | 0.1256 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0319 | 0.0692 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0054 | 0.0498 | 0.2208 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.002 | 0.0084 | 0.013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0337 | 0.1398 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.0466 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.0319 | 0.9619 |
Loa Loa (eye worm) | intermediate filament protein | 0.0057 | 0.0537 | 0.1256 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0337 | 0.2511 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.1189 | 1 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.002 | 0.0084 | 0.013 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0177 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.1189 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0138 | 0.049 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0117 | 0.1268 | 0.4277 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0138 | 0.2951 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0138 | 0.0722 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.013 | 0.1427 | 1 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.037 | 0.0314 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0052 | 0.0473 | 0.1568 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0473 | 0.11 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0278 | 0.08 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.037 | 0.0827 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0319 | 0.1057 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0164 | 0.184 | 0.6095 |
Brugia malayi | topoisomerase | 0.002 | 0.0084 | 0.0277 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0337 | 0.0738 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0351 | 0.0776 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0319 | 0.2354 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0329 | 0.1363 |
Trypanosoma brucei | polo-like protein kinase | 0.0109 | 0.1169 | 1 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.1189 | 1 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0186 | 0.2115 | 0.7006 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0329 | 0.2223 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0101 | 0.1074 | 0.1023 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.1189 | 0.2994 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0329 | 0.0706 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0041 | 0.0337 | 0.0281 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.0319 | 0.0692 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0177 | 0.0315 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.0319 | 0.1753 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0351 | 0.0776 |
Echinococcus granulosus | expressed conserved protein | 0.0095 | 0.0999 | 0.2491 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.037 | 0.0827 |
Brugia malayi | glutathione reductase | 0.0051 | 0.0466 | 0.1545 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.002 | 0.0084 | 0.0958 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.0319 | 0.6397 |
Echinococcus multilocularis | tar DNA binding protein | 0.026 | 0.3019 | 0.2979 |
Schistosoma mansoni | hypothetical protein | 0.0327 | 0.3839 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0319 | 0.1311 |
Echinococcus granulosus | lamin | 0.0057 | 0.0537 | 0.1268 |
Echinococcus granulosus | GPCR family 2 | 0.0052 | 0.0473 | 0.11 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0084 | 0.013 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0138 | 0.2951 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0144 | 0.0782 |
Brugia malayi | RNA, U transporter 1 | 0.0087 | 0.0906 | 0.3 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0084 | 0.013 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0109 | 0.1169 | 0.2929 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Echinococcus granulosus | importin subunit beta 1 | 0.0031 | 0.0215 | 0.0417 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0319 | 0.0943 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Onchocerca volvulus | 0.0024 | 0.0138 | 0.0499 | |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0144 | 0.0435 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0041 | 0.0337 | 0.0738 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0041 | 0.0337 | 0.2511 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.002 | 0.0084 | 0.0958 |
Schistosoma mansoni | topbp1 | 0.002 | 0.0084 | 0.0069 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0063 | 0.0189 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0319 | 0.1311 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0138 | 0.0456 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0473 | 0.11 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0052 | 0.0473 | 0.1088 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0215 | 0.1419 |
Schistosoma mansoni | kinase | 0.0055 | 0.0516 | 0.1211 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0109 | 0.1169 | 0.5568 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.037 | 0.1566 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.0466 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0144 | 0.0782 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0144 | 0.055 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1964 | 0.5041 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.002 | 0.0084 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0058 | 0.0191 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0329 | 0.2447 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0319 | 0.0679 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0116 | 0.053 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.0319 | 0.0943 |
Onchocerca volvulus | 0.0039 | 0.0319 | 0.217 | |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0041 | 0.0337 | 0.0738 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.002 | 0.0084 | 0.0234 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.002 | 0.0084 | 0.0277 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 62.5 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 10536 after 24 hrs by broth microdilution method | ChEMBL. | 20797808 |
MIC (functional) | = 62.5 ug ml-1 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 after 24 hrs by broth microdilution method | ChEMBL. | 20797808 |
MIC (functional) | = 125 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 21 days by broth dilution assay | ChEMBL. | 20797808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.