Detailed information for compound 1195054

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 320.345 | Formula: C18H16N4O2
  • H donors: 1 H acceptors: 1 LogP: 2.93 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)c(/C=C/1\C(=O)N=c3n(C1=N)oc(c3)C)c([nH]2)C
  • InChi: 1S/C18H16N4O2/c1-9-4-5-15-13(6-9)12(11(3)20-15)8-14-17(19)22-16(21-18(14)23)7-10(2)24-22/h4-8,19-20H,1-3H3/b14-8-,19-17?
  • InChiKey: FVSDJTXCXJYFEL-PUOZGBORSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0062 0.0104 0.1316
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.003 0.0037 0.3108
Schistosoma mansoni lamin 0.0058 0.0096 0.1214
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0011 0.0206
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0028 0.1588
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0011 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0047 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0034 0.0654
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0058 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Echinococcus granulosus transcription factor btf3 0.0021 0.0017 0.0164
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0698
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.4765 1 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0024 0.0024 0.0251
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0037 0.0322
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0011 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.003 0.0225
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.009 0.1135
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0047 0.0564
Echinococcus granulosus expressed protein 0.004 0.0059 0.0718
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0228 0.0454 0.0444
Trichomonas vaginalis esterase, putative 0.0024 0.0024 0.0188
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.003 0.0037 0.0722
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0011 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0024 0.0188
Echinococcus granulosus dna polymerase eta 0.0034 0.0046 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0017 0.0123
Brugia malayi hypothetical protein 0.0235 0.0469 0.4238
Brugia malayi CHE-14 protein 0.0051 0.0082 0.0698
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0059 0.0493
Onchocerca volvulus 0.0069 0.012 0.1004
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0082 0.1017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0011 0.008
Onchocerca volvulus 0.0048 0.0075 0.0588
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0033 0.0373
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Echinococcus multilocularis transcription factor btf3 0.0021 0.0017 0.0164
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0011 0.008
Echinococcus granulosus expressed conserved protein 0.0112 0.0209 0.2716
Leishmania major hypothetical protein, conserved 0.0024 0.0024 0.0463
Echinococcus granulosus phd:f box containing protein 0.0026 0.003 0.0329
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0046 0.0542
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0011 0.008
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0026 0.003 0.0329
Leishmania major hypothetical protein, conserved 0.0026 0.003 0.0575
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0259 0.0518 1
Brugia malayi nuclear hormone receptor 0.0018 0.0011 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0011 0.0055
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0011 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0038 0.0732
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0028 0.1994
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0087 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0011 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0011 0.008
Toxoplasma gondii hypothetical protein 0.0042 0.0062 0.5144
Leishmania major basic transcription factor 3a, putative 0.0021 0.0017 0.0337
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0047 0.3942
Trypanosoma brucei transcription factor BTF3, putative 0.0021 0.0017 0.0337
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0228 0.0454 0.0444
Trypanosoma brucei unspecified product 0.0049 0.0077 0.1487
Chlamydia trachomatis cysteine--tRNA ligase 0.0069 0.012 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0068 0.0057
Schistosoma mansoni coup transcription factor 0.0018 0.0011 0.008
Mycobacterium ulcerans hypothetical protein 0.0136 0.0261 0.025
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0057 0.1101
Echinococcus granulosus cysteinyl tRNA synthetase 0.0069 0.012 0.1535
Echinococcus granulosus dna polymerase kappa 0.0054 0.0087 0.1094
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0017 0.0011 0.0888
Schistosoma mansoni hypothetical protein 0.0273 0.0548 0.7224
Mycobacterium tuberculosis Conserved protein 0.0024 0.0024 0.0013
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0228 0.0454 0.0444
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0034 0.0284
Brugia malayi MH2 domain containing protein 0.0144 0.0278 0.2489
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0026 0.003 0.2476
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0015 0.0007 0.0558
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.004 0.0315
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0011 0.008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0096 0.0833
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.003 0.0225
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0259 0.0518 1
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0046 0.0372
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.003 0.0585
Giardia lamblia Fructose-bisphosphate aldolase 0.0467 0.0957 1
Mycobacterium ulcerans glutaminase 0.0234 0.0467 0.0456
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0183 0.2364
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0036 0.0051 0.0978
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0034 0.0654
Plasmodium falciparum basic transcription factor 3b, putative 0.0021 0.0017 0.107
Trichomonas vaginalis ran, putative 0.0026 0.0028 0.0229
Echinococcus multilocularis lamin 0.0058 0.0096 0.1214
Echinococcus multilocularis beta LACTamase domain containing family member 0.0024 0.0024 0.0251
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0047 0.0916
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.009 0.0779
Mycobacterium leprae Probable lipase LipE 0.0024 0.0024 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0024 0.0463
Mycobacterium tuberculosis Conserved hypothetical protein 0.0136 0.0261 0.025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0104 0.1323
Schistosoma mansoni intermediate filament proteins 0.0058 0.0096 0.1214
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0104 0.1323
Entamoeba histolytica Ran family GTPase 0.0026 0.0028 0.0242
Schistosoma mansoni phd/f-box containing protein 0.0026 0.003 0.0329
Echinococcus multilocularis snurportin 1 0.0372 0.0756 1
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0038 0.0732
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Leishmania major GTP-binding protein, putative 0.0026 0.0028 0.0543
Mycobacterium tuberculosis Conserved protein 0.0024 0.0024 0.0013
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0087 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.01 0.1259
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.003 0.0585
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0026 0.003 0.0575
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0068 0.0627
Brugia malayi jmjC domain containing protein 0.0099 0.0183 0.1623
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0966
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0036 0.0051 0.0978
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.009 0.1135
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.003 0.0225
Onchocerca volvulus 0.0024 0.0024 0.0118
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0966
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0005 0.0426
Schistosoma mansoni rotamase 0.004 0.0059 0.0718
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0082 0.1017
Toxoplasma gondii ABC1 family protein 0.0024 0.0024 0.1994
Echinococcus granulosus jumonji domain containing 1A 0.0026 0.003 0.0329
Brugia malayi jmjC domain containing protein 0.0026 0.003 0.0225
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0332 0.4347
Brugia malayi steroid hormone receptor 0.0018 0.0011 0.0055
Plasmodium vivax JmjC domain containing protein 0.0026 0.003 0.1742
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0122 0.0232 0.447
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0011 0.0055
Brugia malayi exodeoxyribonuclease III family protein 0.003 0.0037 0.0295
Echinococcus granulosus snurportin 1 0.0372 0.0756 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0183 0.2364
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Leishmania major cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.2324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0011 0.0055
Mycobacterium tuberculosis Probable hydrolase 0.0024 0.0024 0.0013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0467 0.0957 1
Echinococcus multilocularis dna polymerase kappa 0.0054 0.0087 0.1094
Brugia malayi Inositol-1 0.0045 0.0068 0.0575
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0068 0.5651
Brugia malayi Pre-SET motif family protein 0.0062 0.0104 0.0908
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0068 0.0661
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0068 0.1313
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0046 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0017 0.0123
Trichomonas vaginalis set domain proteins, putative 0.0491 0.1008 1
Plasmodium vivax importin-beta 2, putative 0.0035 0.0047 0.3351
Plasmodium falciparum cysteine--tRNA ligase 0.0069 0.012 1
Mycobacterium tuberculosis Probable lipase LipE 0.0024 0.0024 0.0013
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0011 0.008
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0024 0.1214
Schistosoma mansoni glutaminase 0.0234 0.0467 0.6143
Echinococcus granulosus geminin 0.0273 0.0548 0.7224
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.003 0.0575
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0011 0.0055
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0005 0.0099
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0005 0.0426
Schistosoma mansoni jumonji domain containing protein 0.0099 0.0183 0.2364
Mycobacterium tuberculosis Probable esterase LipL 0.0024 0.0024 0.0013
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0028 0.021
Brugia malayi jmjC domain containing protein 0.0026 0.003 0.0225
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0087 0.1685
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0037 0.2436
Entamoeba histolytica hypothetical protein 0.0017 0.0011 0.0058
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.003 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Echinococcus multilocularis Protein lozenge 0.0067 0.0115 0.1468
Treponema pallidum fructose-bisphosphate aldolase 0.0467 0.0957 1
Echinococcus granulosus lamin dm0 0.0058 0.0096 0.1214
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0077 0.1487
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0011 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.003 0.2185
Onchocerca volvulus 0.0058 0.0096 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0017 0.0123
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.003 0.0329
Onchocerca volvulus 0.0491 0.1008 0.9158
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0011 0.0055
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0011 0.008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0046 0.0542
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0011 0.0055
Echinococcus multilocularis phd:f box containing protein 0.0026 0.003 0.0329
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0028 0.2335
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0235 0.0469 0.4238
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0028 0.0306
Leishmania major phosphopantetheinyl transferase-like protein 0.0017 0.0011 0.0206
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.009 0.1135
Echinococcus multilocularis geminin 0.0273 0.0548 0.7224
Plasmodium falciparum JmjC domain-containing protein, putative 0.0026 0.003 0.2141
Brugia malayi hypothetical protein 0.0535 0.11 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.003 0.0037 0.0722
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.0882 0.8016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0069 0.012 0.1535
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0067 0.1301
Schistosoma mansoni jumonji domain containing protein 0.0026 0.003 0.0329
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Loa Loa (eye worm) inositol-1 0.0045 0.0068 0.0575
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.2324
Toxoplasma gondii exonuclease III APE 0.003 0.0037 0.3108
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0011 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0104 0.1323
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0011 0.0055
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.003 0.2518
Treponema pallidum cysteinyl-tRNA synthetase 0.0069 0.012 0.116
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0011 0.0055
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0017 0.0337
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0028 0.0543
Echinococcus multilocularis jumonji domain containing 1A 0.0026 0.003 0.0329
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0372
Echinococcus multilocularis JmjC domain containing protein 4 0.0026 0.003 0.0329
Echinococcus multilocularis lamin dm0 0.0058 0.0096 0.1214
Plasmodium falciparum importin beta, putative 0.0035 0.0047 0.3672
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0224 0.2003
Schistosoma mansoni inositol monophosphatase 0.0045 0.0068 0.0838
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0011 0.008
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0068 0.0627
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0017 0.0337
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0068 0.1313
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0011 0.008
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0011 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0011 0.0055
Echinococcus multilocularis lysine specific demethylase 5A 0.0099 0.0183 0.2364
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0756 0.6863
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0037 0.2802
Onchocerca volvulus 0.0365 0.0742 0.6715
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0225
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0011 0.008
Echinococcus multilocularis lysine specific demethylase 6a 0.0026 0.003 0.0329
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0057 0.1101
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0011 0.008
Schistosoma mansoni phosphatidylserine receptor 0.0026 0.003 0.0329
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0122 0.0232 0.447
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0082 0.1017
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0024 0.0024 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0036 0.0051 0.0978
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0011 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0056 0.1083
Brugia malayi polk-prov protein 0.003 0.0038 0.03
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.2324
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0068 0.1313
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0011 0.008
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0024 0.0024 0.0173
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0224 0.2918
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.0469 0.6175
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.003 0.0037 0.0339
Brugia malayi Pre-SET motif family protein 0.0432 0.0882 0.8016
Schistosoma mansoni patched 1 0.0051 0.0082 0.1017
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0062 0.0104 0.0903
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0278 0.2489
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.0183 0.2364
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Schistosoma mansoni ap endonuclease 0.003 0.0037 0.043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0966
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.009 0.1135
Loa Loa (eye worm) hypothetical protein 0.0062 0.0104 0.0908
Plasmodium vivax SET domain protein, putative 0.0062 0.0104 0.8549
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0087 0.1685
Brugia malayi beta-lactamase family protein 0.0024 0.0024 0.0173
Loa Loa (eye worm) ICD-1 protein 0.0021 0.0017 0.0113
Echinococcus granulosus importin subunit beta 1 0.0035 0.0047 0.0564
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0235
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0011 0.008
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.003 0.0037 0.0295
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0259 0.0518 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0046 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.0183 0.1623
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.023
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.2324
Loa Loa (eye worm) hypothetical protein 0.0069 0.012 0.1053
Brugia malayi beta-lactamase family protein 0.0024 0.0024 0.0173
Brugia malayi jmjC domain containing protein 0.0099 0.0183 0.1623
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0011 0.0055
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0024 0.0024 0.0013
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0034 0.0284
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0011 0.008
Loa Loa (eye worm) glutaminase 2 0.0234 0.0467 0.4216
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0011 0.008
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0096 0.0833
Echinococcus multilocularis expressed conserved protein 0.0112 0.0209 0.2716
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0024 0.0463
Mycobacterium tuberculosis Probable lipase LipD 0.0024 0.0024 0.0013
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0028 0.0242
Mycobacterium ulcerans esterase/lipase LipP 0.0024 0.0024 0.0013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.009 0.0779
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0011 0.008
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0056 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.009 0.1135
Loa Loa (eye worm) runx1 0.0067 0.0115 0.1007
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0057 0.4739
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0151 0.0292 0.0282
Trichomonas vaginalis DNA polymerase eta, putative 0.0054 0.0087 0.082
Onchocerca volvulus 0.0535 0.11 1
Loa Loa (eye worm) hypothetical protein 0.0535 0.11 1
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0024 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Brugia malayi nuclear receptor NHR-88 0.0018 0.0011 0.0055
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0046 0.0542
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Echinococcus multilocularis dna polymerase eta 0.0034 0.0046 0.0542
Echinococcus granulosus leucyl tRNA synthetase 0.0069 0.012 0.1535
Loa Loa (eye worm) glutaminase 0.0234 0.0467 0.4216
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0046 0.0428
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Onchocerca volvulus 0.0058 0.0096 0.0783
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.003 0.2185
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0068 0.1313
Schistosoma mansoni transcription factor btf3 0.0021 0.0017 0.0164
Brugia malayi intermediate filament protein 0.0058 0.0096 0.0833
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0011 0.0055
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0024 0.0463
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0096 0.0833
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0069 0.012 0.1535
Brugia malayi Importin beta-1 subunit 0.0035 0.0047 0.0387
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0033 0.0373
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0047 0.0916
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.003 0.0037 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0034 0.0654
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Onchocerca volvulus 0.0062 0.0104 0.0853
Echinococcus multilocularis protein dispatched 1 0.0058 0.0097 0.1219
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0034 0.0284
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0028 0.021
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0011 0.0055
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0011 0.008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.003 0.0037 0.0027
Trypanosoma brucei DNA polymerase eta, putative 0.0034 0.0046 0.0884
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Trichomonas vaginalis rotamase, putative 0.004 0.0059 0.0538
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0068 0.0627
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0069 0.012 1
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0069 0.012 0.1053
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0104 0.1323
Mycobacterium ulcerans lipase LipD 0.0024 0.0024 0.0013
Plasmodium falciparum cysteine--tRNA ligase 0.0069 0.012 1
Giardia lamblia Cysteinyl-tRNA synthetase 0.0069 0.012 0.1211
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0122 0.0232 0.447
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0059 0.0538
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0024 0.0251
Brugia malayi hypothetical protein 0.0017 0.001 0.0048
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0224 0.2918
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0467 0.0957 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0024 0.0188
Schistosoma mansoni survival motor neuron protein 0.0048 0.0075 0.0932
Echinococcus granulosus lamin 0.0058 0.0096 0.1214
Schistosoma mansoni ap endonuclease 0.003 0.0037 0.043
Loa Loa (eye worm) beta-lactamase 0.0024 0.0024 0.0173
Brugia malayi glutaminase DH11.1 0.0234 0.0467 0.4216
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0017 0.0011 0.0888
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0017 0.0011 0.0888
Echinococcus granulosus lysine specific demethylase 6a 0.0026 0.003 0.0329
Trypanosoma brucei unspecified product 0.0023 0.0024 0.0455
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0011 0.008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0046 0.0372
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.0469 0.6175
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.003 0.0037 0.0722
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0011 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.009 0.1135
Loa Loa (eye worm) hypothetical protein 0.0058 0.0096 0.0833
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0046 0.0884
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.003 0.0037 0.0722
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.1149
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0173
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0005 0.0099
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0069 0.012 0.011
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.03
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0057 0.1101
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0082 0.0762
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0365 0.0742 0.6733
Brugia malayi hypothetical protein 0.0027 0.003 0.023
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0057 0.0546
Brugia malayi ecdysteroid receptor 0.0018 0.0011 0.0055
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0068 0.0838
Trichomonas vaginalis glutaminase, putative 0.0234 0.0467 0.4601
Brugia malayi jmjC domain containing protein 0.0026 0.003 0.0225
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0228 0.297
Echinococcus granulosus JmjC domain containing protein 4 0.0026 0.003 0.0329
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0183 0.2364
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0332 0.4347
Echinococcus granulosus intermediate filament protein 0.0058 0.0096 0.1214
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0011 0.008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0057 0.1101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0055
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.003 0.0037 0.043
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0932
Loa Loa (eye worm) hypothetical protein 0.0062 0.0106 0.0919
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0011 0.0055
Brugia malayi beta-NAC-like protein 0.0021 0.0017 0.0113
Brugia malayi hypothetical protein 0.0365 0.0742 0.6733
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0011 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0037 0.0322
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0046 0.0372
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0026 0.003 0.2476
Brugia malayi RNA, U transporter 1 0.0099 0.0183 0.1621
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0069 0.012 0.1211
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0069 0.012 1
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.4765 1 1
Toxoplasma gondii NAC domain-containing protein 0.0021 0.0017 0.145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.009 0.1135
Onchocerca volvulus 0.0062 0.0104 0.0858
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.004 0.0315
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0024 0.0024 0.0173
Leishmania major DNA polymerase eta, putative 0.0034 0.0046 0.0884
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.003 0.0329
Loa Loa (eye worm) hypothetical protein 0.0062 0.0104 0.0903
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0069 0.012 0.1053
Trypanosoma brucei unspecified product 0.0023 0.0024 0.0455
Loa Loa (eye worm) hypothetical protein 0.0119 0.0224 0.2003
Schistosoma mansoni importin beta-1 0.0035 0.0047 0.0564
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0011 0.008
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0024 0.0188
Schistosoma mansoni protein phosphatase 2C 0.0026 0.003 0.0329
Leishmania major importin beta-1 subunit, putative 0.0028 0.0034 0.0649
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0034 0.0649
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0011 0.0055
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0028 0.0543
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0068 0.5651
Onchocerca volvulus 0.0024 0.0024 0.0118
Schistosoma mansoni DNA polymerase eta 0.0034 0.0046 0.0542
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0058 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0011 0.0055
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0056 0.1083
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.003 0.1789
Schistosoma mansoni hypothetical protein 0.0273 0.0548 0.7224
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0278 0.2489
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0183 0.2364
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0054 0.0087 0.082
Entamoeba histolytica transcription factor BTF3, putative 0.0021 0.0017 0.013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0966
Brugia malayi beta-lactamase 0.0024 0.0024 0.0173
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0104 0.1323
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0011 0.0483
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0104 0.1323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0011 0.008
Schistosoma mansoni lozenge 0.0067 0.0115 0.1468
Loa Loa (eye worm) hypothetical protein 0.0057 0.0094 0.0813
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0024 0.0251
Echinococcus multilocularis L aminoadipate semialdehyde 0.0062 0.0104 0.1316
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0059 0.0493
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0082 0.0698
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.003 0.0037 0.043
Onchocerca volvulus 0.0024 0.0024 0.0118
Schistosoma mansoni inositol monophosphatase 0.0045 0.0068 0.0838
Echinococcus multilocularis musashi 0.0058 0.0096 0.1214
Leishmania major hypothetical protein, conserved 0.0027 0.003 0.0585
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0068 0.0838
Plasmodium vivax basic transcription factor 3b, putative 0.0021 0.0017 0.0617
Entamoeba histolytica hypothetical protein 0.0021 0.0017 0.013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0024 0.0024 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.003 0.0575
Mycobacterium tuberculosis Conserved protein 0.0024 0.0024 0.0013
Entamoeba histolytica hypothetical protein 0.0028 0.0034 0.0299
Echinococcus granulosus L aminoadipate semialdehyde 0.0062 0.0104 0.1316
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0024 0.0188
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0069 0.012 0.1535
Mycobacterium ulcerans beta-lactamase 0.0024 0.0024 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0256
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Schistosoma mansoni ran 0.0026 0.0028 0.0306
Echinococcus multilocularis protein patched 0.0051 0.0082 0.1017
Giardia lamblia DINP protein human, muc B family 0.0039 0.0056 0.0536
Leishmania major DNA polymerase kappa, putative 0.0039 0.0056 0.1083
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0028 0.0306
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0224 0.2303
Leishmania major mitochondrial DNA polymerase beta 0.0259 0.0518 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0075 0.0639
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0087 0.1685
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0024 0.0188
Trichomonas vaginalis rotamase, putative 0.0039 0.0057 0.0518
Schistosoma mansoni ran 0.0026 0.0028 0.0306
Schistosoma mansoni hypothetical protein 0.0372 0.0756 1
Brugia malayi jmjC domain containing protein 0.0026 0.003 0.0225
Mycobacterium ulcerans hypothetical protein 0.0024 0.0024 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0104 0.1323
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0028 0.0543
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0104 0.8678
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0011 0.0055
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0011 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0467 0.0957 0.949
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0024 0.0024 0.0013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.003 0.0037 0.0339
Loa Loa (eye worm) hypothetical protein 0.0535 0.11 1
Echinococcus multilocularis expressed protein 0.004 0.0059 0.0718
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0036 0.0051 0.0978
Schistosoma mansoni lamin 0.0058 0.0096 0.1214
Treponema pallidum exodeoxyribonuclease (exoA) 0.003 0.0037 0.0283
Plasmodium vivax cysteine--tRNA ligase, putative 0.0069 0.012 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 32.1 uM PUBCHEM_BIOASSAY: Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 33.3 uM PUBCHEM_BIOASSAY: Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) > 100 uM PUBCHEM_BIOASSAY: Dose Response validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.8913 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.9362 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.929 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 32.6427 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) = 70.7946 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 251.1886 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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