Detailed information for compound 1196540

Basic information

Technical information
  • TDR Targets ID: 1196540
  • Name: N-(1,3-benzodioxol-5-yl)-2-[6-ethoxy-3-(4-eth oxybenzoyl)-4-oxoquinolin-1-yl]acetamide
  • MW: 514.526 | Formula: C29H26N2O7
  • H donors: 1 H acceptors: 3 LogP: 4.64 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOc1ccc2c(c1)c(=O)c(cn2CC(=O)Nc1ccc2c(c1)OCO2)C(=O)c1ccc(cc1)OCC
  • InChi: 1S/C29H26N2O7/c1-3-35-20-8-5-18(6-9-20)28(33)23-15-31(24-11-10-21(36-4-2)14-22(24)29(23)34)16-27(32)30-19-7-12-25-26(13-19)38-17-37-25/h5-15H,3-4,16-17H2,1-2H3,(H,30,32)
  • InChiKey: PINVZCJJPQEXGJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(1,3-benzodioxol-5-yl)-2-[6-ethoxy-3-(4-ethoxybenzoyl)-4-oxo-1-quinolyl]acetamide
  • N-(1,3-benzodioxol-5-yl)-2-[6-ethoxy-3-[(4-ethoxyphenyl)-oxomethyl]-4-oxo-1-quinolyl]acetamide
  • N-(1,3-benzodioxol-5-yl)-2-[6-ethoxy-3-(4-ethoxybenzoyl)-4-keto-1-quinolyl]acetamide
  • N-(1,3-benzodioxol-5-yl)-2-[6-ethoxy-3-(4-ethoxyphenyl)carbonyl-4-oxo-quinolin-1-yl]ethanamide
  • C647-0924
  • NCGC00111179-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0707 0.0707
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0137 0.2732 0.2409
Echinococcus granulosus dna polymerase kappa 0.0021 0.0224 0.0224
Brugia malayi hypothetical protein 0.002 0.0193 0.0193
Onchocerca volvulus 0.0043 0.0707 0.0707
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0707 0.0494
Brugia malayi beta-lactamase family protein 0.0043 0.0707 0.0707
Mycobacterium ulcerans hypothetical protein 0.0192 0.3917 0.3777
Loa Loa (eye worm) plexin A 0.002 0.0199 0.0199
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0224 0.0224
Schistosoma mansoni plexin 0.0017 0.0133 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0558 0.0558
Echinococcus granulosus GPCR family 2 0.0017 0.0134 0.0134
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0707 0.0494
Onchocerca volvulus 0.0474 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0474 1 1
Mycobacterium ulcerans hypothetical protein 0.0043 0.0707 0.0494
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Entamoeba histolytica aldose reductase, putative 0.0474 1 1
Loa Loa (eye worm) oxidoreductase 0.0474 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.0134 0.0134
Mycobacterium ulcerans oxidoreductase 0.0474 1 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0707 0.0494
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0707 0.0494
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.3495 0.3346
Brugia malayi Pre-SET motif family protein 0.0036 0.0547 0.0547
Mycobacterium leprae Conserved hypothetical protein 0.0337 0.7036 0.6811
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.5195 0.5195
Loa Loa (eye worm) hypothetical protein 0.0054 0.0924 0.0924
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Plasmodium falciparum aldehyde reductase, putative 0.0137 0.2732 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0474 1 1
Schistosoma mansoni hypothetical protein 0.0037 0.0558 0.0558
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0137 0.2732 0.2409
Toxoplasma gondii ABC1 family protein 0.0043 0.0707 0.0294
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0707 0.0494
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0224 0.0224
Schistosoma mansoni DNA polymerase eta 0.0021 0.0224 0.0224
Giardia lamblia Aldose reductase 0.0474 1 1
Schistosoma mansoni aldo-keto reductase 0.0474 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Loa Loa (eye worm) oxidoreductase 0.0474 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Leishmania major hypothetical protein, conserved 0.0043 0.0707 0.0494
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Toxoplasma gondii hypothetical protein 0.0059 0.1039 0.064
Onchocerca volvulus 0.0036 0.0547 0.0547
Brugia malayi NADH-dependent xylose reductase 0.0137 0.2732 0.2732
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0707 0.1221
Loa Loa (eye worm) oxidoreductase 0.0474 1 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0134 0.0134
Trypanosoma brucei unspecified product 0.0021 0.0224 0.0143
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0876 0.0799
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0707 0.0494
Brugia malayi plexin A 0.002 0.0199 0.0199
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0518 0.0518
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0134 0.0134
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0137 0.2732 0.2732
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0924 0.0924
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Brugia malayi Plexin repeat family protein 0.0017 0.0133 0.0133
Trichomonas vaginalis aldo-keto reductase, putative 0.0137 0.2732 0.2565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0547 0.0547
Echinococcus multilocularis plexin a4 0.002 0.0199 0.0199
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0137 0.2732 0.2732
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0547 0.0547
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.1118 0.0914
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0224 0.0143
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0876 0.0666
Echinococcus granulosus aldehyde reductase 0.0337 0.7036 0.7036
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0474 1 1
Entamoeba histolytica aldose reductase, putative 0.0474 1 1
Trichomonas vaginalis set domain proteins, putative 0.0286 0.5945 0.5852
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0224 0.0224
Brugia malayi hypothetical protein 0.003 0.0426 0.0426
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0224 0.0143
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.3917 0.3777
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0426 0.0346
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Onchocerca volvulus 0.0474 1 1
Echinococcus granulosus aldo keto reductase 0.0474 1 1
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0474 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Leishmania major aldo-keto reductase-like protein 0.0474 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Plasmodium falciparum aldo-keto reductase, putative 0.0137 0.2732 1
Entamoeba histolytica alcohol dehydrogenase, putative 0.0137 0.2732 0.2565
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.5766 0.5669
Onchocerca volvulus 0.0286 0.5945 0.5945
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0707 0.0494
Mycobacterium tuberculosis Probable oxidoreductase 0.0474 1 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.3495 0.3441
Leishmania major hypothetical protein, conserved 0.003 0.0426 0.0206
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0474 1 1
Echinococcus multilocularis aldo keto reductase 0.0474 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0547 0.0547
Loa Loa (eye worm) hypothetical protein 0.0036 0.0547 0.0547
Trypanosoma cruzi aldo/keto reductase, putative 0.0474 1 1
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0474 1 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0021 0.0224 0.0224
Loa Loa (eye worm) oxidoreductase 0.0474 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0707 0.0494
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0707 0.0707
Brugia malayi Pre-SET motif family protein 0.0251 0.5195 0.5195
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0224 0.0143
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0474 1 1
Echinococcus granulosus aldo keto reductase 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0134 0.0134
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0137 0.2732 0.2565
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0876 0.0666
Trypanosoma brucei aldo-keto reductase, putative 0.0474 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0547 0.0547
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0474 1 1
Entamoeba histolytica alcohol dehydrogenase, putative 0.0137 0.2732 0.2565
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0137 0.2732 1
Onchocerca volvulus 0.0474 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0707 0.0707
Trichomonas vaginalis aldo-keto reductase, putative 0.0137 0.2732 0.2565
Schistosoma mansoni potassium channel beta 0.0137 0.2732 0.2732
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0924 0.0924
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0134 0.0134
Loa Loa (eye worm) oxidoreductase 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0474 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0876 0.0666
Mycobacterium ulcerans lipase LipD 0.0043 0.0707 0.0494
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0134 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Echinococcus granulosus aldo keto reductase 0.0474 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.0134 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Trypanosoma brucei prostaglandin f synthase 0.0474 1 1
Trichomonas vaginalis esterase, putative 0.0043 0.0707 0.0494
Echinococcus multilocularis aldehyde reductase 0.0337 0.7036 0.7036
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0707 0.0494
Mycobacterium tuberculosis Conserved protein 0.0043 0.0707 0.0494
Echinococcus multilocularis dna polymerase eta 0.0021 0.0224 0.0224
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0547 0.0127
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0224 0.0143
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0014 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0474 1 1
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0224 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0924 0.0924
Trichomonas vaginalis aldo/keto reductase, putative 0.0474 1 1
Loa Loa (eye worm) transcription factor SMAD2 0.0109 0.2119 0.2119
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0137 0.2732 0.2732
Echinococcus multilocularis aldo keto reductase 0.0474 1 1
Loa Loa (eye worm) beta-lactamase 0.0043 0.0707 0.0707
Schistosoma mansoni aldo-keto reductase 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0426 0.0426
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0137 0.2732 0.2565
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.2732 0.2565
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Toxoplasma gondii aldose reductase, putative 0.0474 1 1
Mycobacterium ulcerans beta-lactamase 0.0043 0.0707 0.0494
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0707 0.0494
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0426 0.0206
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0134 0.0134
Onchocerca volvulus 0.0137 0.2732 0.2732
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Giardia lamblia Aldose reductase 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0133 0.0133
Brugia malayi beta-lactamase family protein 0.0043 0.0707 0.0707
Brugia malayi beta-lactamase 0.0043 0.0707 0.0707
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0547 0.0547
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0707 0.0494
Echinococcus multilocularis GPCR, family 2 0.0017 0.0134 0.0134
Trypanosoma brucei aldo/keto reductase, putative 0.0137 0.2732 0.2671
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0474 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0707 0.0707
Mycobacterium tuberculosis Conserved protein 0.0043 0.0707 0.0494
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0224 0.0143
Trichomonas vaginalis aldo/keto reductase, putative 0.0474 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0426 0.0206
Echinococcus granulosus plexin a4 0.002 0.0199 0.0199
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0474 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0707 0.0494
Onchocerca volvulus 0.0474 1 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0137 0.2732 0.2732
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0707 0.0494
Mycobacterium tuberculosis Conserved protein 0.0043 0.0707 0.0494
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0707 0.0494
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Schistosoma mansoni pol-related 0.0474 1 1
Plasmodium vivax SET domain protein, putative 0.0036 0.0547 0.0525
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.3495 0.3346
Loa Loa (eye worm) hypothetical protein 0.0043 0.0707 0.0707
Mycobacterium tuberculosis Conserved protein 0.0137 0.2732 0.2565
Brugia malayi MH2 domain containing protein 0.0109 0.2119 0.2119
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.7644 0.759
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0224 0.0224
Toxoplasma gondii aldo-keto reductase 0.0137 0.2732 0.2409
Echinococcus multilocularis voltage gated potassium channel subunit 0.0137 0.2732 0.2732
Trypanosoma cruzi aldo-keto reductase 0.0474 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0474 1 1
Onchocerca volvulus 0.0474 1 1
Onchocerca volvulus 0.0474 1 1
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0137 0.2732 0.2565
Echinococcus granulosus hypothetical protein 0.0474 1 1
Echinococcus multilocularis aldo keto reductase 0.0474 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0474 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0707 0.0629
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0707 0.0707
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.7644 0.759
Onchocerca volvulus 0.0017 0.0133 0.0133
Echinococcus multilocularis aldo keto reductase 0.0474 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0134 0.0134
Mycobacterium leprae Possible oxidoreductase 0.0137 0.2732 0.2179
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0547 0.0547
Trypanosoma cruzi aldo/keto reductase, putative 0.0137 0.2732 0.2565
Echinococcus granulosus dna polymerase eta 0.0021 0.0224 0.0224
Entamoeba histolytica aldose reductase, putative 0.0474 1 1
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.7644 0.759
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.7644 0.7624
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0224 0.0224
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0224 0.0224
Onchocerca volvulus 0.0043 0.0707 0.0707
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0707 0.0494
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0707 0.0707
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0558 0.0558
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0547 0.0547
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0063 0.0063
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0707 0.0494
Schistosoma mansoni hypothetical protein 0.0017 0.0134 0.0134
Mycobacterium ulcerans hypothetical protein 0.0137 0.2732 0.2565
Onchocerca volvulus 0.0043 0.0707 0.0707
Leishmania major prostaglandin f synthase, putative 0.0474 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.0134 0.0134
Loa Loa (eye worm) MH2 domain-containing protein 0.0109 0.2119 0.2119
Plasmodium vivax aldehyde reductase, putative 0.0137 0.2732 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0063 0.0063

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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