TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 472.45 | Formula: C25H20N4O6
H donors: 3 H acceptors: 6 LogP: 4.03 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: OC(Cn1nc(cc1C(=O)O)c1cccc(c1)[N+](=O)[O-])COc1cccc2c1c1ccccc1[nH]2
InChi: 1S/C25H20N4O6/c30-17(14-35-23-10-4-9-20-24(23)18-7-1-2-8-19(18)26-20)13-28-22(25(31)32)12-21(27-28)15-5-3-6-16(11-15)29(33)34/h1-12,17,26,30H,13-14H2,(H,31,32)
InChiKey: IJADQMRMZYBTRL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0622	1
Plasmodium falciparum	dihydrolipoyl dehydrogenase, apicoplast	0.0035	0.0559	0.1212
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.0035	0.0559	0.0167
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0144	0.3955	0.4983
Echinococcus multilocularis	tar DNA binding protein	0.0076	0.183	0.1483
Brugia malayi	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein	0.0026	0.027	0.0334
Mycobacterium ulcerans	extragenic suppressor protein SuhB	0.0037	0.0622	0.0185
Echinococcus granulosus	thioredoxin glutathione reductase	0.0102	0.263	0.2317
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.0769
Mycobacterium tuberculosis	Probable lipase LipD	0.0036	0.0593	0.0132
Schistosoma mansoni	lamin	0.0032	0.0458	0.0056
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0035	0.0559	0.1212
Mycobacterium tuberculosis	Conserved protein	0.0036	0.0593	0.0132
Brugia malayi	beta-lactamase family protein	0.0036	0.0593	0.0733
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0593	0.5392
Brugia malayi	Intermediate filament tail domain containing protein	0.0032	0.0458	0.0566
Loa Loa (eye worm)	RNA binding protein	0.0076	0.183	0.2261
Schistosoma mansoni	tar DNA-binding protein	0.0076	0.183	0.1564
Echinococcus granulosus	short transient receptor potential channel 6	0.0066	0.1522	0.1162
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0593	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Brugia malayi	beta-lactamase	0.0036	0.0593	0.0733
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0144	0.3955	1
Toxoplasma gondii	NADPH-glutathione reductase	0.0035	0.0559	0.0769
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0036	0.0593	0.0733
Trichomonas vaginalis	penicillin-binding protein, putative	0.0036	0.0593	0.5392
Mycobacterium ulcerans	hypothetical protein	0.0036	0.0593	0.01
Loa Loa (eye worm)	transcription factor SMAD2	0.012	0.3219	0.3976
Echinococcus granulosus	beta LACTamase domain containing family member	0.0036	0.0593	0.0194
Trypanosoma cruzi	trypanothione reductase, putative	0.0035	0.0559	0.1212
Brugia malayi	glutathione reductase	0.0101	0.2611	0.3225
Plasmodium vivax	hypothetical protein, conserved	0.003	0.0407	0.0562
Plasmodium vivax	hypothetical protein, conserved	0.0036	0.0593	0.1357
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0593	0.5392
Echinococcus granulosus	transient receptor potential gamma protein	0.01	0.2571	0.2256
Onchocerca volvulus		0.0036	0.0593	0.307
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0035	0.0559	0.5
Echinococcus multilocularis	lysine specific demethylase 5A	0.0036	0.0604	0.0205
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Echinococcus granulosus	geminin	0.0203	0.5782	0.5603
Plasmodium vivax	thioredoxin reductase, putative	0.0101	0.2611	1
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0036	0.0593	0.01
Echinococcus multilocularis	tumor protein p63	0.0339	1	1
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0036	0.0593	0.0194
Onchocerca volvulus		0.0032	0.0458	0.0842
Trypanosoma brucei	hypothetical protein, conserved	0.0036	0.0593	0.1357
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.0037	0.0622	1
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0521	0.0643
Echinococcus granulosus	short transient receptor potential channel 6	0.0066	0.1522	0.1162
Toxoplasma gondii	aldehyde dehydrogenase	0.0144	0.3955	1
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.023	0.6633	0.8847
Trichomonas vaginalis	penicillin-binding protein, putative	0.0036	0.0593	0.5392
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0144	0.3955	1
Schistosoma mansoni	intermediate filament proteins	0.0032	0.0458	0.0056
Schistosoma mansoni	aldehyde dehydrogenase	0.0144	0.3955	0.3901
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0256	0.7432	1
Schistosoma mansoni	transient receptor potential channel	0.0066	0.1522	0.1225
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0622	0.1481
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0276	0.0341
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.0035	0.0559	0.0158
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0593	0.1357
Loa Loa (eye worm)	hypothetical protein	0.003	0.0407	0.0503
Echinococcus multilocularis	transient receptor potential gamma protein	0.01	0.2571	0.2256
Onchocerca volvulus		0.0032	0.0458	0.0842
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0099	0.2537	0.222
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.023	0.6633	0.8847
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0036	0.0593	0.0132
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0035	0.0559	0.0691
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Echinococcus granulosus	TRP transient receptor potential channel	0.0037	0.0624	0.0226
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.0037	0.0624	0.0226
Onchocerca volvulus		0.0036	0.0593	0.307
Loa Loa (eye worm)	MH2 domain-containing protein	0.012	0.3219	0.3976
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0593	0.0204
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.0035	0.0559	0.0158
Plasmodium falciparum	glutathione reductase	0.0035	0.0559	0.1212
Loa Loa (eye worm)	hypothetical protein	0.0052	0.1076	0.1329
Brugia malayi	Bromodomain containing protein	0.003	0.0407	0.0503
Plasmodium falciparum	thioredoxin reductase	0.0101	0.2611	1
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0256	0.7432	1
Schistosoma mansoni	hypothetical protein	0.0203	0.5782	0.5909
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0102	0.263	0.2317
Toxoplasma gondii	thioredoxin reductase	0.0101	0.2611	0.6346
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0036	0.0604	0.0217
Echinococcus granulosus	lamin	0.0032	0.0458	0.0053
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.023	0.6633	0.8847
Toxoplasma gondii	PHD-finger domain-containing protein	0.003	0.0407	0.0356
Mycobacterium tuberculosis	Probable hydrolase	0.0036	0.0593	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0458	0.0566
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0144	0.3955	0.3698
Trichomonas vaginalis	esterase, putative	0.0036	0.0593	0.5392
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0036	0.0593	0.0733
Loa Loa (eye worm)	beta-lactamase	0.0036	0.0593	0.0733
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0076	0.183	0.2261
Echinococcus granulosus	tar DNA binding protein	0.0076	0.183	0.1483
Schistosoma mansoni	cellular tumor antigen P53	0.005	0.1012	0.0665
Loa Loa (eye worm)	hypothetical protein	0.005	0.1012	0.125
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Echinococcus multilocularis	geminin	0.0203	0.5782	0.5603
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0035	0.0559	0.1212
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0035	0.0559	0.1212
Plasmodium vivax	dihydrolipoyl dehydrogenase, apicoplast, putative	0.0035	0.0559	0.1212
Loa Loa (eye worm)	glutathione reductase	0.0101	0.2611	0.3225
Brugia malayi	RNA recognition motif domain containing protein	0.0076	0.183	0.2261
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Echinococcus granulosus	lysine specific demethylase 5A	0.0036	0.0604	0.0205
Leishmania major	acetoin dehydrogenase e3 component-like protein	0.0035	0.0559	0.0769
Brugia malayi	RNA binding protein	0.0076	0.183	0.2261
Mycobacterium tuberculosis	Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot	0.0035	0.0559	0.0083
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0593	0.5392
Brugia malayi	follicle stimulating hormone receptor	0.0277	0.8097	1
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0037	0.0622	0.094
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0622	0.1481
Echinococcus multilocularis	transient receptor potential ion channel A	0.0096	0.2468	0.2148
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0622	1
Plasmodium falciparum	glutathione reductase	0.0101	0.2611	1
Schistosoma mansoni	tar DNA-binding protein	0.0076	0.183	0.1564
Brugia malayi	Inositol-1	0.0037	0.0622	0.0768
Echinococcus multilocularis	short transient receptor potential channel 6	0.0066	0.1522	0.1162
Echinococcus multilocularis	jumonji domain containing protein	0.0042	0.0774	0.0382
Brugia malayi	Thioredoxin reductase	0.0101	0.2611	0.3225
Schistosoma mansoni	tar DNA-binding protein	0.0076	0.183	0.1564
Mycobacterium tuberculosis	Probable dehydrogenase	0.023	0.6633	0.8847
Brugia malayi	PHD-finger family protein	0.003	0.0407	0.0503
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0101	0.2611	0.3043
Mycobacterium tuberculosis	Probable oxidoreductase	0.0256	0.7432	1
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0622	0.1481
Echinococcus multilocularis	musashi	0.0032	0.0458	0.0053
Schistosoma mansoni	transient receptor potential channel	0.01	0.2571	0.2379
Echinococcus granulosus	inositol monophosphatase 1	0.0037	0.0622	0.0224
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.023	0.6633	0.8847
Mycobacterium ulcerans	beta-lactamase	0.0036	0.0593	0.01
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0036	0.0593	0.0132
Mycobacterium tuberculosis	Probable lipase LipE	0.0036	0.0593	0.0132
Brugia malayi	MH2 domain containing protein	0.012	0.3219	0.3976
Mycobacterium leprae	conserved hypothetical protein	0.0036	0.0593	0.0132
Plasmodium falciparum	thioredoxin reductase	0.0035	0.0559	0.1212
Treponema pallidum	NADH oxidase	0.0035	0.0559	0.5
Brugia malayi	beta-lactamase family protein	0.0036	0.0593	0.0733
Mycobacterium tuberculosis	Conserved protein	0.0036	0.0593	0.0132
Echinococcus multilocularis	short transient receptor potential channel 6	0.0066	0.1522	0.1162
Brugia malayi	Transient-receptor-potential like protein	0.0037	0.0624	0.0771
Loa Loa (eye worm)	PHD-finger family protein	0.003	0.0407	0.0503
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.0769
Mycobacterium ulcerans	lipase LipD	0.0036	0.0593	0.01
Plasmodium falciparum	phd finger protein, putative	0.003	0.0407	0.0562
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.0037	0.0622	0.5
Loa Loa (eye worm)	TAR-binding protein	0.0076	0.183	0.2261
Echinococcus multilocularis	inositol monophosphatase 1	0.0037	0.0622	0.0224
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0035	0.0559	0.1212
Mycobacterium tuberculosis	Probable esterase LipL	0.0036	0.0593	0.0132
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0035	0.0559	0.1212
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0622	0.094
Loa Loa (eye worm)	thioredoxin reductase	0.0101	0.2611	0.3225
Brugia malayi	hypothetical protein	0.0026	0.0276	0.0341
Loa Loa (eye worm)	jmjC domain-containing protein	0.0036	0.0604	0.0746
Trypanosoma cruzi	trypanothione reductase, putative	0.0101	0.2611	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0593	0.1357
Loa Loa (eye worm)	hypothetical protein	0.0063	0.1418	0.1752
Echinococcus multilocularis	lamin dm0	0.0032	0.0458	0.0053
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0099	0.2537	0.222
Echinococcus granulosus	transient receptor potential ion channel A	0.0096	0.2468	0.2148
Leishmania major	2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein	0.0035	0.0559	0.0769
Mycobacterium tuberculosis	Conserved protein	0.0036	0.0593	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0624	0.0771
Echinococcus granulosus	jumonji domain containing protein	0.0042	0.0774	0.0382
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0144	0.3955	0.3698
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0256	0.7432	1
Brugia malayi	jmjC domain containing protein	0.0099	0.2537	0.3134
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0622	0.0236
Echinococcus granulosus	lamin dm0	0.0032	0.0458	0.0053
Schistosoma mansoni	transient receptor potential channel 4	0.01	0.2571	0.2379
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0036	0.0604	0.0217
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0035	0.0559	0.1212
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0277	0.8097	1
Brugia malayi	alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase	0.0026	0.027	0.0334
Schistosoma mansoni	jumonji domain containing protein	0.0078	0.1907	0.1649
Brugia malayi	intermediate filament protein	0.0032	0.0458	0.0566
Giardia lamblia	NADH oxidase lateral transfer candidate	0.0035	0.0559	1
Trichomonas vaginalis	inositol monophosphatase, putative	0.0037	0.0622	1
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.023	0.6639	0.8856
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0593	0.0733
Leishmania major	trypanothione reductase	0.0101	0.2611	0.6346
Brugia malayi	jmjC domain containing protein	0.0036	0.0604	0.0746
Brugia malayi	TAR-binding protein	0.0076	0.183	0.2261
Plasmodium vivax	dihydrolipoyl dehydrogenase, mitochondrial, putative	0.0035	0.0559	0.1212
Mycobacterium leprae	Probable lipase LipE	0.0036	0.0593	0.0132
Echinococcus multilocularis	lamin	0.0032	0.0458	0.0053
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0622	0.0236
Loa Loa (eye worm)	jmjC domain-containing protein	0.0062	0.1404	0.1734
Schistosoma mansoni	hypothetical protein	0.0203	0.5782	0.5909
Plasmodium falciparum	dihydrolipoyl dehydrogenase, mitochondrial	0.0035	0.0559	0.1212
Schistosoma mansoni	lamin	0.0032	0.0458	0.0056
Schistosoma mansoni	aldehyde dehydrogenase	0.0144	0.3955	0.3901
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0144	0.3955	1
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0035	0.0559	0.1212
Loa Loa (eye worm)	hypothetical protein	0.0031	0.044	0.0544
Onchocerca volvulus		0.0036	0.0593	0.307
Trypanosoma brucei	trypanothione reductase	0.0101	0.2611	1
Loa Loa (eye worm)	intermediate filament protein	0.0032	0.0458	0.0566
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0036	0.0593	0.0132
Loa Loa (eye worm)	hypothetical protein	0.01	0.2571	0.3176
Toxoplasma gondii	PHD-finger domain-containing protein	0.003	0.0407	0.0356
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.023	0.6633	0.8847
Echinococcus granulosus	intermediate filament protein	0.0032	0.0458	0.0053
Toxoplasma gondii	ABC1 family protein	0.0036	0.0593	0.0861
Leishmania major	hypothetical protein, conserved	0.0036	0.0593	0.0861
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0144	0.3955	1
Mycobacterium ulcerans	esterase/lipase LipP	0.0036	0.0593	0.01
Onchocerca volvulus		0.005	0.1012	1
Loa Loa (eye worm)	inositol-1	0.0037	0.0622	0.0768
Toxoplasma gondii	pyruvate dehydrogenase complex subunit PDH-E3II	0.0035	0.0559	0.0769
Schistosoma mansoni	transient receptor potential channel	0.0066	0.1522	0.1225
Mycobacterium tuberculosis	Probable reductase	0.023	0.6633	0.8847
Plasmodium vivax	glutathione reductase, putative	0.0101	0.2611	1
Schistosoma mansoni	tar DNA-binding protein	0.0076	0.183	0.1564
Schistosoma mansoni	tar DNA-binding protein	0.0076	0.183	0.1564
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0032	0.0458	0.0566

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1277724

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1197536