Detailed information for compound 1199144

Basic information

Technical information
  • TDR Targets ID: 1199144
  • Name: N-(2,5-diethoxyphenyl)-2-[3-methyl-4-(3-methy lphenyl)piperazin-1-yl]acetamide hydrochlorid e
  • MW: 447.998 | Formula: C24H34ClN3O3
  • H donors: 1 H acceptors: 1 LogP: 5.03 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1NC(=O)CN1CCN(C(C1)C)c1cccc(c1)C)OCC.Cl
  • InChi: 1S/C24H33N3O3.ClH/c1-5-29-21-10-11-23(30-6-2)22(15-21)25-24(28)17-26-12-13-27(19(4)16-26)20-9-7-8-18(3)14-20;/h7-11,14-15,19H,5-6,12-13,16-17H2,1-4H3,(H,25,28);1H
  • InChiKey: WRNVJHAOGSMMMV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,5-diethoxyphenyl)-2-[3-methyl-4-(m-tolyl)piperazin-1-yl]acetamide hydrochloride
  • N-(2,5-diethoxyphenyl)-2-[3-methyl-4-(m-tolyl)-1-piperazinyl]acetamide hydrochloride
  • N-(2,5-diethoxyphenyl)-2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]ethanamide hydrochloride
  • MLS000889425
  • MLS000030125
  • N-(2,5-Diethoxy-phenyl)-2-(3-methyl-4-m-tolyl-piperazin-1-yl)-acetamide
  • SMR000000825

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0035 0.0105 0.0087
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0027 0.0058 0.004
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0018 0.0018
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0026 0.0008
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0287 0.027
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Brugia malayi photoreceptor-specific nuclear receptor 0.0109 0.0536 0.0536
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Brugia malayi nuclear hormone receptor 0.0109 0.0536 0.0536
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Onchocerca volvulus 0.0109 0.0536 0.1867
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0536 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis dna polymerase eta 0.0021 0.0026 0.0008
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0035 0.0105 0.0087
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.0117 0.0372
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0034 0.0102 0.0171
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0035 0.0105 0.0334
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0067 0.0326
Brugia malayi hypothetical protein 0.0058 0.0238 0.0238
Mycobacterium tuberculosis Conserved protein 0.0223 0.1192 0.1447
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0127 0.064 0.0623
Schistosoma mansoni Smad4 0.0076 0.0346 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0151 0.0134
Leishmania major acetoin dehydrogenase e3 component-like protein 0.01 0.0484 0.2729
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0058 0.0276
Mycobacterium tuberculosis Putative ferredoxin reductase 0.066 0.372 0.4562
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.1747 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Plasmodium vivax ferrodoxin reductase, putative 0.0027 0.0058 0.004
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0207 0.019
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0035 0.0105 0.0087
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0536 0.0519
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0547
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0161 0.0143
Toxoplasma gondii ubiquitin-specific protease USP4 0.0035 0.0105 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0123 0.0406
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0083 0.0385 0.0452
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0058 0.0155
Schistosoma mansoni transcription factor LCR-F1 0.0481 0.2686 0.2673
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0024 0.0006
Schistosoma mansoni patched 1 0.0043 0.0151 0.0134
Brugia malayi Ets-domain containing protein 0.0084 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.006 0.025 0.0232
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.1145 0.6522 0.6501
Schistosoma mansoni apoferritin-2 0.0152 0.0785 0.0769
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0035 0.0105 0.0087
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0086
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0141 0.0721 0.0705
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0161 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.1192 0.4515
Onchocerca volvulus 0.0029 0.0073 0.0059
Leishmania major DNA polymerase eta, putative 0.0021 0.0026 0.0046
Echinococcus multilocularis expressed conserved protein 0.0094 0.0445 0.0428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Plasmodium vivax thioredoxin reductase, putative 0.0289 0.1577 0.1562
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0058 0.0236
Brugia malayi beta-lactamase 0.0223 0.1192 0.1192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi Importin beta-1 subunit 0.0028 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0348
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.025 0.0232
Echinococcus multilocularis mothers against decapentaplegic 2 0.0034 0.0102 0.0084
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus granulosus mothers against decapentaplegic 2 0.0034 0.0102 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0202 0.0563
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0027 0.0058 0.004
Schistosoma mansoni cpg binding protein 0.0029 0.0073 0.0056
Entamoeba histolytica hypothetical protein 0.0023 0.0036 0.0068
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0025 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi ecdysteroid receptor 0.0109 0.0536 0.0536
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.066 0.372 0.3683
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus tar DNA binding protein 0.0351 0.1933 0.1919
Loa Loa (eye worm) hypothetical protein 0.0034 0.0102 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Mycobacterium tuberculosis Probable dehydrogenase 0.066 0.372 0.4562
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0109 0.0536 0.0519
Brugia malayi mothers against decapentaplegic homolog 3 0.0034 0.0102 0.0102
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0052 0.0202 0.0202
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0035
Trichomonas vaginalis esterase, putative 0.0223 0.1192 0.4515
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.016 0.0143
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.1747 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0287 0.027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.01 0.0484 0.2729
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0027 0.0058 0.004
Echinococcus granulosus geminin 0.0205 0.1087 0.1071
Brugia malayi nuclear receptor NHR-88 0.0109 0.0536 0.0536
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.01 0.0484 0.0467
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0006
Trichomonas vaginalis glutathione reductase, putative 0.01 0.0484 0.1792
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0035 0.0105 0.0087
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0287 0.027
Plasmodium falciparum ferrodoxin reductase-like protein 0.0027 0.0058 0.004
Leishmania major hypothetical protein, conserved 0.0223 0.1192 0.6874
Echinococcus granulosus mothers against decapentaplegic 6 0.0034 0.0102 0.0084
Loa Loa (eye worm) hypothetical protein 0.0286 0.1555 0.154
Schistosoma mansoni rotamase 0.0038 0.0122 0.0105
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0058 0.0236
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0052 0.0202 0.0185
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.01 0.0484 0.2758
Plasmodium falciparum ubiquitin specific protease, putative 0.0035 0.0105 0.0087
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0035 0.0105 0.0087
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Brugia malayi nuclear receptor RXR 0.0052 0.0202 0.0202
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0026 0.0026
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0027 0.0058 0.004
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Brugia malayi Isocitrate dehydrogenase 0.0083 0.0385 0.0385
Brugia malayi nuclear hormone receptor 0.0052 0.0202 0.0202
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0037 0.0117 0.0581
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0122 0.0612 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0481 0.2686 0.2673
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Schistosoma mansoni glutamate synthase 0.0027 0.0058 0.004
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Mycobacterium ulcerans bacterioferritin BfrA 0.0152 0.0785 0.0769
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0152 0.0785 0.0946
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0287 0.0287
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Leishmania major dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0109 0.0536 0.0536
Schistosoma mansoni ferritin 0.0152 0.0785 0.0769
Schistosoma mansoni hypothetical protein 0.0066 0.0287 0.027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0221
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0027 0.0058 0.004
Brugia malayi hypothetical protein 0.0052 0.0202 0.0202
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0108 0.0569
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0161 0.055
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0027 0.0058 0.0236
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0035 0.0105 0.0087
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0727 0.0711
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0216 0.1163
Leishmania major hypothetical protein, conserved 0.0026 0.0053 0.0204
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0223 0.1192 0.1447
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1555 0.154
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0035 0.0105 0.0087
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0108 0.009
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0083 0.0385 0.0368
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0035 0.0105 0.0325
Loa Loa (eye worm) nuclear factor I 0.0042 0.0149 0.0131
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0109 0.0536 0.0519
Echinococcus multilocularis mothers against decapentaplegic 6 0.0034 0.0102 0.0084
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.0864 0.1043
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0102 0.0084
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0108 0.009
Mycobacterium tuberculosis Probable hydrolase 0.0223 0.1192 0.1447
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0058 0.0151
Schistosoma mansoni glutamate synthase 0.0027 0.0058 0.004
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0035 0.0105 0.1863
Schistosoma mansoni survival motor neuron protein 0.0058 0.0241 0.0224
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0026 0.0008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0109 0.0536 0.0519
Brugia malayi Bromodomain containing protein 0.0035 0.0108 0.0108
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0035 0.0105 0.0087
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0035 0.0105 0.0087
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0489 0.0472
Brugia malayi jmjC domain containing protein 0.0044 0.016 0.016
Loa Loa (eye worm) DR-78 0.0052 0.0202 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0096
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0418 0.0401
Echinococcus multilocularis tar DNA binding protein 0.0351 0.1933 0.1919
Loa Loa (eye worm) hypothetical protein 0.01 0.048 0.0463
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0734 0.4145 0.4111
Echinococcus multilocularis musashi 0.0264 0.1429 0.1414
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.01 0.0484 0.2758
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0027 0.0058 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0209 0.1115 0.1115
Mycobacterium ulcerans lipase LipD 0.0223 0.1192 0.1176
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0152 0.0785 0.0946
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0058 0.0236
Giardia lamblia Thioredoxin reductase 0.0027 0.0058 0.0867
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0058 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Brugia malayi MH2 domain containing protein 0.1122 0.6391 0.6391
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0026 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Treponema pallidum bacterioferrin (TpF1) 0.0152 0.0785 0.0769
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0223 0.1192 0.1192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Mycobacterium ulcerans glutamate synthase subunit beta 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0109 0.0536 0.0519
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0026 0.0008
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0058 0.004
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0027 0.0058 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.01 0.0484 0.0467
Echinococcus granulosus ubiquitin specific peptidase c family 0.0035 0.0105 0.0087
Plasmodium falciparum thioredoxin reductase 0.0289 0.1577 0.1562
Schistosoma mansoni lamin 0.0264 0.1429 0.1414
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0325
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0223 0.1192 0.4515
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Toxoplasma gondii ABC1 family protein 0.0223 0.1192 0.1176
Onchocerca volvulus 0.0223 0.1192 0.4429
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0221
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Brugia malayi MH2 domain containing protein 0.0076 0.0346 0.0346
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0109 0.0536 0.0519
Brugia malayi beta-lactamase family protein 0.0223 0.1192 0.1192
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.066 0.372 0.4562
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.025 0.0232
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Loa Loa (eye worm) programmed cell death 8 0.0027 0.0058 0.004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0287 0.027
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0027 0.0058 0.0155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0035 0.0105 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0046
Mycobacterium ulcerans monoxygenase 0.0027 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0385 0.0368
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0161 0.0837
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.1747 1 1
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0027 0.0058 0.0151
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0035 0.0105 0.0087
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0602 0.3382 0.3344
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.016 0.0872
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi CXXC zinc finger family protein 0.0029 0.0073 0.0073
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0109 0.0536 0.0519
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0223 0.1192 0.1176
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0161 0.0874
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0418 0.0418
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0095 0.0077
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0026 0.0046
Echinococcus multilocularis smad 0.0076 0.0346 0.0329
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0026 0.0046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0052 0.0202 0.0185
Brugia malayi MH1 domain containing protein 0.0042 0.0149 0.0149
Brugia malayi hypothetical protein 0.0481 0.2686 0.2686
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Schistosoma mansoni importin beta-1 0.0028 0.0067 0.0049
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Schistosoma mansoni hypothetical protein 0.0205 0.1087 0.1071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) isocitrate dehydrogenase 0.0083 0.0385 0.0368
Brugia malayi Nuclear hormone receptor-like 1 0.0109 0.0536 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.016 0.0143
Echinococcus granulosus TGF beta signal transducer SmadC 0.0076 0.0346 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0036 0.0107
Schistosoma mansoni hypothetical protein 0.0205 0.1087 0.1071
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Plasmodium falciparum phd finger protein, putative 0.0035 0.0108 0.009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) nuclear hormone receptor 0.0052 0.0202 0.0185
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0027 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0095
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.01 0.0484 0.0467
Entamoeba histolytica hypothetical protein 0.0035 0.0105 0.0325
Brugia malayi MH2 domain containing protein 0.0076 0.0346 0.0346
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0024 0.0006
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0734 0.4145 0.5087
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0083 0.0385 0.2179
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0418 0.0401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0026 0.0086
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0202 0.0185
Echinococcus multilocularis snurportin 1 0.03 0.1638 0.1624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Brugia malayi nuclear hormone receptor family member nhr-6 0.0052 0.0202 0.0202
Brugia malayi Ets-domain containing protein 0.0084 0.039 0.039
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0087
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0223 0.1192 0.1176
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0058 0.0155
Echinococcus granulosus intermediate filament protein 0.0264 0.1429 0.1414
Schistosoma mansoni ferritin 0.0152 0.0785 0.0769
Onchocerca volvulus 0.0052 0.0202 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0147
Entamoeba histolytica hypothetical protein 0.0481 0.2686 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Brugia malayi nuclear hormone receptor family member odr-7 0.0052 0.0202 0.0202
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Echinococcus multilocularis isocitrate dehydrogenase 0.0083 0.0385 0.0368
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0109 0.0536 0.0536
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0418 0.0401
Onchocerca volvulus 0.0035 0.0105 0.0181
Loa Loa (eye worm) hypothetical protein 0.1747 1 1
Giardia lamblia GTOR 0.0044 0.0161 0.3067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0035 0.0105 0.0087
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1423 0.8132 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus expressed protein 0.0038 0.0122 0.0105
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0035 0.0105 0.0334
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0058 0.0151
Brugia malayi RNA recognition motif domain containing protein 0.0351 0.1933 0.1933
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0109 0.0536 0.0536
Schistosoma mansoni smad 0.0034 0.0102 0.0084
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.01 0.0484 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Echinococcus granulosus snurportin 1 0.03 0.1638 0.1624
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Schistosoma mansoni cpg binding protein 0.0031 0.0083 0.0065
Toxoplasma gondii hypothetical protein 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0109 0.0536 0.0519
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0161 0.0837
Echinococcus granulosus GA binding protein alpha chain 0.0084 0.039 0.0373
Schistosoma mansoni hypothetical protein 0.0041 0.0142 0.0125
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0076
Onchocerca volvulus 0.0264 0.1429 0.5354
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus granulosus lamin 0.0264 0.1429 0.1414
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0187 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.3132 0.312
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0236
Echinococcus granulosus importin subunit beta 1 0.0028 0.0067 0.0049
Echinococcus multilocularis ubiquitin specific protease 41 0.0035 0.0105 0.0087
Brugia malayi MH1 domain containing protein 0.0076 0.0346 0.0346
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0027 0.0058 0.004
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0083 0.0385 0.2147
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0413 0.2289 0.2276
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0027 0.0058 0.004
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0035 0.0105 0.0087
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0026 0.003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0221
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0238 0.0238
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus smad 0.0076 0.0346 0.0329
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni hypothetical protein 0.0041 0.0142 0.0125
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0026 0.0008
Plasmodium falciparum ubiquitin specific protease, putative 0.0035 0.0105 0.0087
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Plasmodium vivax ubiquitin specific protease, putative 0.0035 0.0105 0.0087
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.016 0.0835
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0072 0.032 0.0303
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0053 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Leishmania major GTP-binding protein, putative 0.0021 0.0024 0.0036
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0035 0.0105 0.1863
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0027 0.0058 0.0151
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.1227 0.6995 0.699
Brugia malayi PHD-finger family protein 0.0035 0.0108 0.0108
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0027 0.0058 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.025 0.0232
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0236
Loa Loa (eye worm) MH2 domain-containing protein 0.0076 0.0346 0.0329
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0161 0.0161
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0058 0.0155
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0202 0.0202
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0385 0.2147
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0202 0.0185
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis expressed protein 0.0152 0.0785 0.0769
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0046
Echinococcus multilocularis thioredoxin glutathione reductase 0.029 0.158 0.1565
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0027 0.0058 0.004
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Mycobacterium ulcerans NADH dehydrogenase 0.0027 0.0058 0.004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0385 0.0368
Brugia malayi Pre-SET motif family protein 0.0413 0.2289 0.2289
Toxoplasma gondii hypothetical protein 0.0602 0.3382 0.3371
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0418 0.0401
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0026 0.003
Schistosoma mansoni thyroid hormone receptor 0.1336 0.7627 0.7623
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Onchocerca volvulus 0.006 0.025 0.0748
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi tailless protein 0.0052 0.0202 0.0202
Schistosoma mansoni ran 0.0021 0.0024 0.0006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.5564 0.5556
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Brugia malayi steroid hormone receptor 0.0109 0.0536 0.0536
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni steroid hormone receptor ad4bp 0.0109 0.0536 0.0519
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0036
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0109 0.0536 0.0519
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0035 0.0105 0.0087
Mycobacterium ulcerans hypothetical protein 0.0166 0.0864 0.0848
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0264 0.1429 0.1414
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.048 0.1733
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0109 0.0536 0.0519
Schistosoma mansoni smad1 5 8 and 0.0076 0.0346 0.0329
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0026 0.0008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0109 0.0536 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0571 0.0554
Onchocerca volvulus 0.0223 0.1192 0.4429
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0027 0.0058 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0035 0.0105 0.0087
Echinococcus granulosus lamin dm0 0.0264 0.1429 0.1414
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0035 0.0105 0.0087
Schistosoma mansoni intermediate filament proteins 0.0264 0.1429 0.1414
Toxoplasma gondii isocitrate dehydrogenase 0.0083 0.0385 0.0368
Mycobacterium ulcerans dehydrogenase 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi CHE-14 protein 0.0043 0.0151 0.0151
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Leishmania major mitochondrial DNA polymerase beta 0.0315 0.1726 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0315 0.1726 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) MH1 domain-containing protein 0.0076 0.0346 0.0329
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0035 0.0105 0.0087
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.016 0.0835
Plasmodium falciparum importin beta, putative 0.0028 0.0067 0.0049
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.1747 1 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.01 0.0484 1
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0035 0.0105 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0202 0.0185
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Trypanosoma brucei trypanothione reductase 0.0289 0.1577 0.913
Echinococcus multilocularis Smad4 0.0076 0.0346 0.0329
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Echinococcus granulosus peptidase Clp S14 family 0.1145 0.6522 0.6516
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0058 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0008
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0035 0.0105 0.0087
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0035 0.0105 0.0325
Leishmania major importin beta-1 subunit, putative 0.0023 0.0036 0.0107
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Schistosoma mansoni cpg binding protein 0.0031 0.0083 0.0065
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0027 0.0058 0.005
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0035 0.0105 0.0087
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0058 0.0238 0.0221
Onchocerca volvulus 0.0035 0.0105 0.0181
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.016 0.0143
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0058 0.004
Trypanosoma brucei NADH dehydrogenase 0.0027 0.0058 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0481 0.2686 0.2673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi jmjC domain containing protein 0.0115 0.0571 0.0571
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0035 0.0105 0.0087
Schistosoma mansoni hypothetical protein 0.0066 0.0287 0.027
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Leishmania major trypanothione reductase 0.0289 0.1577 0.9126
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.01 0.0484 0.0467
Echinococcus granulosus expressed protein 0.0152 0.0785 0.0769
Schistosoma mansoni hypothetical protein 0.03 0.1638 0.1624
Echinococcus granulosus dna polymerase eta 0.0021 0.0026 0.0008
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0026 0.0086
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0027 0.0058 0.004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0385 0.0368
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi trypanothione reductase, putative 0.0289 0.1577 0.9126
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0108 0.009
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0204
Treponema pallidum thioredoxin reductase (trxB) 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis GPCR, family 2 0.0066 0.0287 0.027
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0324 0.0307
Loa Loa (eye worm) hypothetical protein 0.0259 0.1401 0.1386
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0024 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0027 0.0058 0.004
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0058 0.004
Brugia malayi hypothetical protein 0.0058 0.0238 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0348
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0027 0.0058 0.0236
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.1145 0.6522 0.8016
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0767 0.4383
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0602 0.3382 0.3371
Giardia lamblia PHD finger protein 15 0.0035 0.0108 0.1931
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0109 0.0536 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0037 0.0117 0.0619
Loa Loa (eye worm) hypothetical protein 0.0127 0.064 0.0623
Loa Loa (eye worm) beta-lactamase 0.0223 0.1192 0.1176
Echinococcus multilocularis peregrin 0.0035 0.0108 0.009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.01 0.0484 0.0467
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.1726 1
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0027 0.0058 0.004
Schistosoma mansoni tar DNA-binding protein 0.0351 0.1933 0.1919
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.025 0.0232
Schistosoma mansoni peptidase Clp (S14 family) 0.1747 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0058 0.004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0035
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0035 0.0105 0.1863
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0035
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0223 0.1192 0.1176
Echinococcus granulosus beta LACTamase domain containing family member 0.0223 0.1192 0.1176
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Toxoplasma gondii thioredoxin reductase 0.0289 0.1577 0.1562
Echinococcus granulosus nuclear receptor nhr 48 0.0052 0.0202 0.0185
Brugia malayi hypothetical protein 0.0026 0.0053 0.0053
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0238 0.0238
Schistosoma mansoni hypothetical protein 0.0066 0.0287 0.027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Plasmodium falciparum glutathione reductase 0.0289 0.1577 0.1562
Brugia malayi latrophilin 2 splice variant baaae 0.0143 0.0732 0.0732
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0035 0.0105 0.0087
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0035 0.0105 0.0087
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0105 0.0087
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0035 0.0105 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0071 0.0204
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.048 0.048
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0161 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni lamin 0.0264 0.1429 0.1414
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0602 0.3382 0.3371
Echinococcus granulosus glutamate synthase 0.0027 0.0058 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Onchocerca volvulus 0.0264 0.1429 0.5354
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0067 0.0326
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0108 0.009
Plasmodium vivax glutathione reductase, putative 0.0289 0.1577 0.1562
Trypanosoma cruzi trypanothione reductase, putative 0.01 0.0484 0.2729
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.01 0.0484 0.0467
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0109 0.0536 0.0536
Brugia malayi RNA, U transporter 1 0.008 0.0366 0.0366
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0084 0.039 0.0373
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.01 0.0484 0.0484
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.1192 0.6874
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Echinococcus multilocularis nuclear receptor nhr 48 0.0052 0.0202 0.0185
Schistosoma mansoni ferritin light chain 0.0152 0.0785 0.0769
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Schistosoma mansoni hypothetical protein 0.0027 0.0058 0.004
Mycobacterium tuberculosis Probable lipase LipE 0.0223 0.1192 0.1447
Trichomonas vaginalis ubiquitin specific protease, putative 0.0035 0.0105 0.0334
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0058 0.0155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Mycobacterium ulcerans ferredoxin reductase 0.0027 0.0058 0.004
Entamoeba histolytica hypothetical protein 0.0481 0.2686 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0151 0.0514
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0117 0.0581
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0035 0.0105 0.0087
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.01 0.0484 0.0575
Leishmania major DNA polymerase kappa, putative 0.0021 0.0026 0.0046
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0035 0.0105 0.0087
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0035 0.0105 0.0087
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1555 0.154
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0058 0.0236
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0102 0.0084
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.3132 0.312
Echinococcus multilocularis protein patched 0.0043 0.0151 0.0134
Schistosoma mansoni gabp alpha 0.0084 0.039 0.0373
Schistosoma mansoni disulfide oxidoreductase 0.0027 0.0058 0.004
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Brugia malayi conserved hypotetical protein 0.0052 0.0202 0.0202
Mycobacterium ulcerans hypothetical protein 0.0223 0.1192 0.1176
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.4721 0.4711
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0027 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0348
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Schistosoma mansoni ferritin 0.0152 0.0785 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trichomonas vaginalis ran, putative 0.0021 0.0024 0.0023
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Schistosoma mansoni ferritin 0.0152 0.0785 0.0769
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0026 0.001
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.01 0.0484 0.0467
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0083 0.0385 0.0368
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Schistosoma mansoni hypothetical protein 0.0041 0.0142 0.0125
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0083 0.0385 0.0368
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0109 0.0536 0.0519
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0035 0.0105 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.025 0.0232
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.025 0.0232
Schistosoma mansoni hypothetical protein 0.0481 0.2686 0.2673
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Schistosoma mansoni nuclear receptor 0.0052 0.0202 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0161 0.0143
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0109 0.0536 0.0536
Schistosoma mansoni nuclear hormone receptor 0.0109 0.0536 0.0519
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0058 0.004
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0385 0.2179
Onchocerca volvulus 0.0035 0.0105 0.0181
Onchocerca volvulus Alhambra homolog 0.0035 0.0108 0.0194
Brugia malayi Thioredoxin reductase 0.0289 0.1577 0.1577
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0058 0.0236
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0109 0.0536 0.0519
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0052 0.0202 0.0185
Plasmodium falciparum glutathione reductase 0.01 0.0484 0.0467
Trichomonas vaginalis penicillin-binding protein, putative 0.0223 0.1192 0.4515
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0418 0.0401
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0289 0.1577 0.1922
Mycobacterium leprae Probable lipase LipE 0.0223 0.1192 0.1141
Giardia lamblia DUB-1 0.0035 0.0105 0.1863
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Echinococcus multilocularis peptidase Clp (S14 family) 0.1145 0.6522 0.6516
Brugia malayi MH1 domain containing protein 0.0076 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0143 0.0732 0.0715
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0109 0.0536 0.0519
Loa Loa (eye worm) steroid hormone receptor 0.0109 0.0536 0.0519
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.1192 0.4515
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Toxoplasma gondii selenide, water dikinase 0.0027 0.0058 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0109 0.0536 0.1867
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.048 0.0463
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0058 0.004
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0734 0.4145 0.5087
Entamoeba histolytica thioredoxin reductase, putative 0.0027 0.0058 0.0151
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0036 0.007
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0027 0.0058 0.005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0035 0.0035
Mycobacterium leprae conserved hypothetical protein 0.0223 0.1192 0.1141
Loa Loa (eye worm) hypothetical protein 0.0043 0.0151 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0096
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Entamoeba histolytica Ran family GTPase 0.0021 0.0024 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Echinococcus granulosus cpg binding protein 0.0031 0.0083 0.0065
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0035 0.0105 0.0087
Giardia lamblia Glutamate synthase 0.0027 0.0058 0.0867
Schistosoma mansoni hypothetical protein 0.1227 0.6995 0.699
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis expressed protein 0.0035 0.0105 0.0087
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus granulosus Smad4 0.0076 0.0346 0.0329
Mycobacterium tuberculosis Conserved protein 0.0223 0.1192 0.1447
Brugia malayi MH1 domain containing protein 0.0042 0.0149 0.0149
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.009
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0035 0.0105 0.0087
Schistosoma mansoni glutamate synthase 0.0027 0.0058 0.004
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0035 0.0105 0.1863
Echinococcus multilocularis ecdysone induced protein 78C 0.0109 0.0536 0.0519
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0221
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0202 0.0185
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0027 0.0058 0.004
Echinococcus multilocularis thyroid hormone receptor alpha 0.1336 0.7627 0.7623
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0058 0.0238 0.0221
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.01 0.0484 0.2729
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0027 0.0058 0.004
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.01 0.0484 0.2729
Toxoplasma gondii hypothetical protein 0.0051 0.0198 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0058 0.0238 0.0221
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Trichomonas vaginalis set domain proteins, putative 0.047 0.2618 1
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0109 0.0536 0.0519
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0536 0.0536
Brugia malayi Intermediate filament tail domain containing protein 0.0264 0.1429 0.1429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0046
Echinococcus granulosus microtubule associated protein 2 0.0833 0.4721 0.4711
Brugia malayi Fli-1 protein 0.0255 0.138 0.138
Brugia malayi hypothetical protein 0.0035 0.0105 0.0105
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0131
Echinococcus multilocularis expressed protein 0.0038 0.0122 0.0105
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0223 0.1192 0.1447
Loa Loa (eye worm) MH2 domain-containing protein 0.1122 0.6391 0.6384
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0035 0.0105 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Schistosoma mansoni DNA polymerase eta 0.0021 0.0026 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0434 0.0417
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus dna polymerase kappa 0.0021 0.0026 0.0008
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0223 0.1192 0.1447
Toxoplasma gondii isocitrate dehydrogenase 0.0083 0.0385 0.0368
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0209 0.1115 0.1115
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0024 0.0006
Brugia malayi RNA binding protein 0.0351 0.1933 0.1933
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0237 0.022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0233 0.0216
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Schistosoma mansoni ferritin light chain 0.0152 0.0785 0.0769
Loa Loa (eye worm) Smad1 0.0076 0.0346 0.0329
Entamoeba histolytica disulphide oxidoreductase, putative 0.0027 0.0058 0.0151
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0035 0.0105 0.0087
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Brugia malayi Pre-SET motif family protein 0.006 0.025 0.025
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0109 0.0536 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0053 0.0244
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0058 0.0236
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0035 0.0105 0.0087
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0571 0.0554
Echinococcus granulosus mothers against decapentaplegic 5 0.0076 0.0346 0.0329
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0067 0.0049
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0035 0.0105 0.0087
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.01 0.0484 0.0467
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.025 0.0232
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0027 0.0058 0.005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Onchocerca volvulus 0.0058 0.0241 0.0714
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0073 0.0056
Echinococcus granulosus ubiquitin specific protease 41 0.0035 0.0105 0.0087
Echinococcus granulosus ecdysone induced protein 78C 0.0109 0.0536 0.0519
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0035 0.0105 0.0087
Mycobacterium tuberculosis Conserved protein 0.0223 0.1192 0.1447
Brugia malayi orphan nuclear receptor NR2E1 0.0052 0.0202 0.0202
Schistosoma mansoni calpain-7 (C02 family) 0.0035 0.0105 0.0087
Schistosoma mansoni ran 0.0021 0.0024 0.0006
Schistosoma mansoni coup transcription factor 0.0109 0.0536 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Mycobacterium ulcerans esterase/lipase LipP 0.0223 0.1192 0.1176
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0202 0.0185
Mycobacterium tuberculosis Probable oxidoreductase 0.0734 0.4145 0.5087
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0036
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0083 0.0385 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0095
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0052 0.0202 0.0185
Schistosoma mansoni retinoic acid receptor RXR 0.0109 0.0536 0.0519
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0035 0.0105 0.0087
Loa Loa (eye worm) glutathione reductase 0.0289 0.1577 0.1562
Plasmodium falciparum thioredoxin reductase 0.01 0.0484 0.0467
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0202 0.0185
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0035 0.0105 0.0087
Brugia malayi nuclear receptor NHR-67 0.0052 0.0202 0.0202
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0536 0.0519
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0035 0.0105 0.0087
Loa Loa (eye worm) transcription factor SMAD2 0.1122 0.6391 0.6384
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0076 0.0346 0.0329
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0204
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0058 0.004
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis cpg binding protein 0.0031 0.0083 0.0065
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0418 0.0401
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0161 0.0874
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Toxoplasma gondii peptidylprolyl isomerase 0.0037 0.0117 0.0099
Echinococcus multilocularis GA binding protein alpha chain 0.0084 0.039 0.0373
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.3132 0.312
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0109 0.0536 0.0519
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0035 0.0105 0.0087
Treponema pallidum oxidoreductase 0.0027 0.0058 0.004
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0027 0.0058 0.004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0287 0.027
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0027 0.0058 0.004
Entamoeba histolytica hypothetical protein 0.0481 0.2686 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.016 0.0143
Schistosoma mansoni smad1 5 8 and 0.0076 0.0346 0.0329
Schistosoma mansoni zinc finger protein 0.0052 0.0202 0.0185
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.1227 0.6995 0.699
Brugia malayi hypothetical protein 0.0052 0.0202 0.0202
Echinococcus granulosus thyroid hormone receptor alpha 0.0052 0.0202 0.0185
Schistosoma mansoni Smad4 0.0034 0.0102 0.0084
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.01 0.0484 0.0428
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi ubiquitin specific protease 14 0.0035 0.0105 0.0105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0223 0.1192 0.1176
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0202 0.0563
Mycobacterium ulcerans beta-lactamase 0.0223 0.1192 0.1176
Trichomonas vaginalis rotamase, putative 0.0038 0.0122 0.0401
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.066 0.372 0.4562
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0536 0.0536
Brugia malayi glutamate synthase 0.0027 0.0058 0.0058
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Schistosoma mansoni nuclear receptor nhr-48 0.0052 0.0202 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0058 0.0236
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Trichomonas vaginalis mercuric reductase, putative 0.01 0.0484 0.1792
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0264 0.1429 0.1414
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0151 0.0133
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0058 0.0236
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0027 0.0058 0.004
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0027 0.0058 0.0276
Schistosoma mansoni tar DNA-binding protein 0.0351 0.1933 0.1919
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0187 0.017
Mycobacterium ulcerans flavoprotein disulfide reductase 0.01 0.0484 0.0467
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.01 0.0484 0.2758
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0035 0.0105 0.0087
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0161 0.055
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0122 0.0401
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0767 0.4383
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0241 0.0241
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0026 0.003
Echinococcus multilocularis ferritin 0.0152 0.0785 0.0769
Schistosoma mansoni thyroid hormone receptor 0.1336 0.7627 0.7623
Plasmodium vivax hypothetical protein, conserved 0.0223 0.1192 0.1176
Schistosoma mansoni hypothetical protein 0.0058 0.0241 0.0224
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0035 0.0105 0.0087
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0035 0.0105 0.0087
Schistosoma mansoni Smad4 0.0034 0.0102 0.0084
Echinococcus multilocularis beta LACTamase domain containing family member 0.0223 0.1192 0.1176
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.066 0.372 0.4562
Echinococcus multilocularis mothers against decapentaplegic 5 0.0076 0.0346 0.0329
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0027 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0275 0.0258
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0058 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi hypothetical protein 0.0286 0.1555 0.1555
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0035 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0052 0.0202 0.0185
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0109 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0105 0.0334
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0074 0.033 0.033
Schistosoma mansoni RAR-like nuclear receptor 0.0109 0.0536 0.0519
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0035 0.0105 0.0087
Leishmania major dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0418 0.0401
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0151 0.0134
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0109 0.0536 0.0519
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0035 0.0105 0.0087
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0058 0.0236
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0027 0.0058 0.0867
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0127 0.064 0.0623
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0087
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0038 0.0122 0.0122
Loa Loa (eye worm) thioredoxin reductase 0.0289 0.1577 0.1562
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0727 0.0711
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0035 0.0105 0.0087
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.1638 0.1624
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.025 0.0232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0109 0.0536 0.0519
Trichomonas vaginalis ubiquitin specific protease, putative 0.0035 0.0105 0.0334
Brugia malayi nuclear receptor RXR 0.0058 0.0238 0.0238
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0109 0.0536 0.0519
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0351 0.1933 0.1919
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0202 0.0185
Schistosoma mansoni ets-related 0.0255 0.138 0.1365
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Onchocerca volvulus 0.0223 0.1192 0.4429
Giardia lamblia Hypothetical protein 0.0035 0.0105 0.1863
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni hypothetical protein 0.0041 0.0142 0.0125
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0161 0.0143
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0287 0.0287
Mycobacterium ulcerans bacterioferritin BfrB 0.0152 0.0785 0.0769
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0109 0.0536 0.0519
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0152 0.0785 0.0731
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0109 0.0536 0.1867
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0058 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Echinococcus multilocularis protein dispatched 1 0.0049 0.0186 0.0169
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0418 0.0401
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0035 0.0105 0.0087
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0151 0.0134
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0035 0.0105 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0076 0.0346 0.0329
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0536 0.0536
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus ferritin 0.0152 0.0785 0.0769
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0161 0.0837
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0035 0.0105 0.0087
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus multilocularis lamin 0.0264 0.1429 0.1414
Schistosoma mansoni hypothetical protein 0.0066 0.0287 0.027
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.01 0.0484 0.2758
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0035 0.0105 0.0087
Brugia malayi TAR-binding protein 0.0351 0.1933 0.1933
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0087
Plasmodium vivax SET domain protein, putative 0.006 0.025 0.0232
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0161 0.0837
Mycobacterium ulcerans hypothetical protein 0.0027 0.0058 0.004
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0038 0.0122 0.0105
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0036 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) RNA binding protein 0.0351 0.1933 0.1919
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0027 0.0058 0.004
Brugia malayi isocitrate dehydrogenase 0.0083 0.0385 0.0385
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Giardia lamblia DINP protein human, muc B family 0.0021 0.0026 0.0169
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.01 0.0484 0.0467
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0108 0.0531
Brugia malayi intermediate filament protein 0.0264 0.1429 0.1429
Echinococcus multilocularis lamin dm0 0.0264 0.1429 0.1414
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.048 0.0463
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0108 0.009
Schistosoma mansoni peptidase 0.0035 0.0105 0.0087
Onchocerca volvulus Bile acid receptor homolog 0.0109 0.0536 0.1867
Brugia malayi beta-lactamase family protein 0.0223 0.1192 0.1192
Schistosoma mansoni calpain-7 (C02 family) 0.0035 0.0105 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Brugia malayi Steroid receptor seven-up type 2 0.0109 0.0536 0.0536
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.01 0.0484 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0297
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0035 0.0105 0.0087
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0117 0.0581
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0074 0.033 0.033
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Trichomonas vaginalis ferritin, putative 0.0152 0.0785 0.295
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0151 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0536 0.0536
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.1145 0.6522 0.8016
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0202 0.0185
Schistosoma mansoni nuclear receptor 0.0052 0.0202 0.0185
Loa Loa (eye worm) hypothetical protein 0.0209 0.1115 0.1099
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0027 0.0058 0.004
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.4721 0.4711
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0202 0.0202
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0076 0.0225
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0161 0.055
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0035 0.0105 0.0087
Brugia malayi MH2 domain containing protein 0.0034 0.0102 0.0102
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0238 0.0221
Schistosoma mansoni tar DNA-binding protein 0.0351 0.1933 0.1919
Schistosoma mansoni smad 0.0076 0.0346 0.0329
Trypanosoma brucei hypothetical protein, conserved 0.0223 0.1192 0.6886
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0008
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Echinococcus granulosus GPCR family 2 0.0066 0.0287 0.027
Loa Loa (eye worm) hypothetical protein 0.0122 0.0612 0.0596
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Entamoeba histolytica hypothetical protein 0.0481 0.2686 1
Loa Loa (eye worm) fli-1 protein 0.0255 0.138 0.1365
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0027 0.0058 0.005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0209 0.1115 0.1099
Echinococcus multilocularis FTZ F1 alpha 0.0109 0.0536 0.0519
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0053 0.0035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Mycobacterium tuberculosis Probable esterase LipL 0.0223 0.1192 0.1447
Loa Loa (eye worm) nuclear receptor NHR-67 0.0052 0.0202 0.0185
Mycobacterium tuberculosis Probable lipase LipD 0.0223 0.1192 0.1447
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0086
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0058 0.0238 0.0221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0351 0.1933 0.1919
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0052 0.0202 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0058 0.0153
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Echinococcus granulosus neuropeptide s receptor 0.0558 0.3132 0.312
Schistosoma mansoni apoferritin-2 0.0152 0.0785 0.0769
Schistosoma mansoni tar DNA-binding protein 0.0351 0.1933 0.1919
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.1747 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0152 0.0785 0.0769
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.1747 1 1
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0035 0.0105 0.0087
Loa Loa (eye worm) hypothetical protein 0.006 0.0253 0.0236
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Brugia malayi glutathione reductase 0.0289 0.1577 0.1577
Loa Loa (eye worm) hypothetical protein 0.0223 0.1192 0.1176
Loa Loa (eye worm) TAR-binding protein 0.0351 0.1933 0.1919
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0036 0.007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0105 0.0105
Brugia malayi Smad1 0.0076 0.0346 0.0346
Leishmania major NADH dehydrogenase, putative 0.0027 0.0058 0.0236
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0026 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0202 0.0185
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.01 0.0484 0.0467
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0035 0.0105 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0058 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0086
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.1192 0.4515
Onchocerca volvulus 0.047 0.2618 1
Mycobacterium tuberculosis Probable reductase 0.066 0.372 0.4562
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0109 0.0536 0.0519
Trichomonas vaginalis ubiquitin specific protease, putative 0.0035 0.0105 0.0334
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0027 0.0058 0.0151
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.1726 1
Echinococcus granulosus peregrin 0.0035 0.0108 0.009
Echinococcus granulosus FTZ F1 alpha 0.0109 0.0536 0.0519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0348
Echinococcus granulosus thioredoxin glutathione reductase 0.029 0.158 0.1565
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.01 0.0484 0.2729
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0536 0.0536
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0105 0.0325
Brugia malayi cytoplasmic intermediate filament protein 0.0141 0.0721 0.0721
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0287 0.027
Toxoplasma gondii NADPH-glutathione reductase 0.01 0.0484 0.0467
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0035 0.0105 0.0087
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0058 0.0155
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0027 0.0058 0.0155
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0385 0.2147
Treponema pallidum NADH oxidase 0.01 0.0484 0.0467
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0067 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0536 0.0519
Trichomonas vaginalis rotamase, putative 0.0037 0.0117 0.0382
Onchocerca volvulus 0.0052 0.0202 0.0563
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0035 0.0105 0.0087
Echinococcus granulosus expressed conserved protein 0.0094 0.0445 0.0428
Brugia malayi ecdysone receptor 0.0052 0.0202 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0096
Trichomonas vaginalis apoptosis inducing factor, putative 0.0027 0.0058 0.0155
Loa Loa (eye worm) intermediate filament protein 0.0264 0.1429 0.1414
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0058 0.0276
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0035 0.0105 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0058 0.0153
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Loa Loa (eye worm) hypothetical protein 0.0042 0.0149 0.0131
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.016 0.0835
Echinococcus multilocularis geminin 0.0205 0.1087 0.1071
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0161 0.0143
Trypanosoma brucei unspecified product 0.0021 0.0026 0.0086
Schistosoma mansoni hypothetical protein 0.0143 0.0732 0.0715
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0105 0.0334
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0547
Schistosoma mansoni smad1 5 8 and 0.0076 0.0346 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0095
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0108 0.0531
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0008
Plasmodium vivax importin-beta 2, putative 0.0028 0.0067 0.0049
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0105 0.0508
Loa Loa (eye worm) hypothetical protein 0.0109 0.0536 0.0519
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0536 0.0519
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0046
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0602 0.3382 0.3371
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0767 0.4406
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.1192 0.6874
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0035 0.0105 0.0508
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0105 0.0508
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.1747 1 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0058 0.0276
Brugia malayi nuclear receptor NHR-88 0.0052 0.0202 0.0202
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0083 0.0385 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0109 0.0536 0.0519
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0108 0.009
Echinococcus multilocularis glutamate synthase 0.0027 0.0058 0.004

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.122 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 3.9811 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 4.1475 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (binding) = 5.6234 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.581 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 44.5625 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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