Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.024 | 0.5016 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0188 | 0.0175 |
Schistosoma mansoni | apoptosis regulator bax | 0.0085 | 0.0558 | 0.0546 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.046 | 0.0448 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.0946 | 0.1589 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.024 | 0.0228 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Treponema pallidum | NADH oxidase | 0.0013 | 0.0047 | 1 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0126 | 0.0161 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0229 | 0.5852 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0066 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0558 | 0.0546 |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.0212 | 0.0199 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0013 | 0.0047 | 0.0372 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0126 | 0.0113 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.3607 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.0304 | 0.0484 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0013 | 0.0047 | 0.0194 |
Echinococcus granulosus | snurportin 1 | 0.0355 | 0.2482 | 0.2472 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0825 | 0.5836 | 0.583 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.024 | 0.9527 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.0126 | 0.2616 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0188 | 0.5235 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0229 | 0.0355 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.024 | 0.2437 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0089 | 0.0583 | 0.32 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0314 | 0.0503 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0283 | 0.0271 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0057 | 0.036 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Onchocerca volvulus | 0.0139 | 0.0946 | 0.5475 | |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0013 | 0.0047 | 0.0372 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0139 | 0.0946 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0188 | 0.0285 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0085 | 0.0558 | 0.0546 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0355 | 0.2482 | 0.4221 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0229 | 0.8952 |
Mycobacterium ulcerans | putative regulatory protein | 0.0037 | 0.0212 | 0.2135 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0009 | 0.0018 | 0.0005 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.1319 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0225 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.025 | 0.1451 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.2482 | 0.2472 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.024 | 0.1275 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0144 | 0.1793 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.02 | 0.0306 |
Onchocerca volvulus | 0.0033 | 0.0188 | 0.0877 | |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.025 | 0.5265 |
Brugia malayi | hypoxia-induced factor 1 | 0.0153 | 0.1041 | 0.1753 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0057 | 0.036 | 0.0348 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.004 | 0.024 | 0.1275 |
Onchocerca volvulus | 0.0037 | 0.0212 | 0.1025 | |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0043 | 0.003 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0066 | 0.0058 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.024 | 0.0358 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0232 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.024 | 0.1395 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0175 | 0.3327 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0229 | 1 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0085 | 0.0558 | 0.0905 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0225 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0066 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0139 | 0.0946 | 0.1589 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0057 | 0.036 | 0.0348 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0089 | 0.0583 | 0.32 |
Brugia malayi | hypothetical protein | 0.0166 | 0.1133 | 0.191 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0066 | 0.0054 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0066 | 0.0054 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0013 | 0.0047 | 0.1319 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0225 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0314 | 0.0486 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0139 | 0.0946 | 0.5577 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.024 | 0.0375 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1409 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0188 | 0.5235 |
Schistosoma mansoni | single-minded | 0.0049 | 0.0304 | 0.0291 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.025 | 0.5265 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0142 | 0.0966 | 0.0954 |
Echinococcus multilocularis | neuroligin | 0.0139 | 0.0946 | 0.0934 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0139 | 0.0946 | 0.5577 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.024 | 0.6219 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0057 | 0.036 | 0.0348 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0175 | 0.0163 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0043 | 0.0225 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0201 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0558 | 0.0905 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0283 | 0.0449 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.0212 | 0.0199 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0085 | 0.0558 | 0.0922 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.0126 | 0.2042 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0126 | 0.0113 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0142 | 0.0966 | 0.1623 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0144 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Onchocerca volvulus | 0.004 | 0.024 | 0.1196 | |
Schistosoma mansoni | ran | 0.0024 | 0.0126 | 0.0113 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.024 | 0.0375 |
Loa Loa (eye worm) | carboxylesterase | 0.0139 | 0.0946 | 0.1574 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1133 | 0.1896 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0201 | 0.0188 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0175 | 0.0163 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.025 | 0.0237 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.036 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0057 | 0.036 | 1 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.024 | 0.1395 |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0188 | 0.0176 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0043 | 0.0225 |
Onchocerca volvulus | 0.004 | 0.024 | 0.1196 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0259 | 0.1796 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.0946 | 0.1589 |
Onchocerca volvulus | 0.0139 | 0.0946 | 0.5475 | |
Echinococcus granulosus | geminin | 0.0514 | 0.3618 | 0.361 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.024 | 0.0228 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0139 | 0.0946 | 0.5232 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0144 | 0.3176 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0188 | 0.0176 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.024 | 0.0358 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.004 | 0.024 | 0.1275 |
Schistosoma mansoni | acetylcholinesterase | 0.0139 | 0.0946 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0314 | 0.0486 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0089 | 0.0583 | 0.89 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.025 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.024 | 0.0228 |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0188 | 0.7788 |
Echinococcus granulosus | acetylcholinesterase | 0.0825 | 0.5836 | 0.583 |
Echinococcus granulosus | carboxylesterase 5A | 0.0825 | 0.5836 | 0.583 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.02 | 0.0187 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.4074 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0085 | 0.0558 | 0.0546 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.2741 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0057 | 0.036 | 0.0564 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0057 | 0.036 | 0.0348 |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.024 | 0.2437 |
Echinococcus granulosus | neuroligin | 0.0139 | 0.0946 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0188 | 0.0269 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0066 | 0.0054 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0013 | 0.0047 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.4551 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0175 | 0.0163 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0225 | 0.5676 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0013 | 0.0047 | 0.0142 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0043 | 0.047 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.024 | 0.6219 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.024 | 0.6219 |
Onchocerca volvulus | 0.0031 | 0.0175 | 0.0803 | |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0057 | 0.036 | 1 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0126 | 0.2509 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0057 | 0.036 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0033 | 0.002 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0229 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0047 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.2741 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0472 | 0.3314 | 0.3305 |
Brugia malayi | beta-lactamase | 0.004 | 0.024 | 0.0375 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0283 | 0.0271 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.4551 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0057 | 0.036 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.0946 | 0.1589 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0031 | 0.0019 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0229 | 0.0355 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0018 | 0.0005 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0013 | 0.0047 | 0.0142 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.024 | 0.1275 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0013 | 0.0047 | 0.0142 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0232 | 0.022 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0066 | 0.0054 |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.0212 | 0.0327 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0229 | 0.0338 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0047 | 0.0252 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.004 | 0.024 | 0.1275 |
Mycobacterium leprae | Probable lipase LipE | 0.004 | 0.024 | 0.3546 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1409 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0057 | 0.036 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0229 | 0.6347 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0139 | 0.0946 | 0.0934 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0139 | 0.0946 | 0.0934 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0099 | 0.0654 | 0.3596 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0126 | 0.2616 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0032 | 0.0017 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.0005 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0067 | 0.0432 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0558 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.013 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.024 | 0.1275 |
Loa Loa (eye worm) | carboxylesterase | 0.0139 | 0.0946 | 0.1574 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0033 | 0.002 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0013 | 0.0043 | 0.003 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0175 | 0.0163 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.024 | 0.0228 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0283 | 0.0271 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0043 | 0.0225 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0225 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0153 | 0.1041 | 0.1738 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.036 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0031 | 0.0019 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0057 | 0.036 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.024 | 0.1395 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0043 | 0.0225 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0066 | 0.0054 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0215 | 0.1481 | 0.2496 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0283 | 0.0432 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.1319 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0043 | 0.0225 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.024 | 0.0375 |
Echinococcus multilocularis | acetylcholinesterase | 0.0825 | 0.5836 | 0.583 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0314 | 0.0503 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.024 | 0.6671 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0126 | 0.3878 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0229 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.0058 |
Schistosoma mansoni | ran | 0.0024 | 0.0126 | 0.0113 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0142 | 0.0966 | 0.0954 |
Mycobacterium tuberculosis | Probable hydrolase | 0.004 | 0.024 | 0.1275 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0043 | 0.003 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.024 | 0.2437 |
Mycobacterium tuberculosis | Probable reductase | 0.0089 | 0.0583 | 0.32 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0201 | 0.0188 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0139 | 0.0946 | 0.0934 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0126 | 0.2616 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0283 | 0.0271 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0175 | 0.0163 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.036 | 0.2105 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.024 | 0.1395 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0126 | 0.0179 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0283 | 0.0271 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0283 | 0.0271 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0013 | 0.0043 | 0.0018 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0175 | 0.0163 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0099 | 0.0654 | 1 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0225 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.013 | 0.2145 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0175 | 0.0264 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0126 | 0.4332 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0047 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3618 | 0.361 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.013 | 0.2741 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.004 | 0.024 | 0.1275 |
Echinococcus multilocularis | geminin | 0.0514 | 0.3618 | 0.361 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0066 | 0.0054 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0085 | 0.0558 | 0.0546 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0009 | 0.0018 | 0.0005 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0085 | 0.0558 | 0.0546 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0067 | 0.0077 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0558 | 0.0546 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0057 | 0.036 | 0.8137 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0089 | 0.0583 | 0.32 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0126 | 0.3497 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.024 | 0.1395 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.02 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0043 | 0.0018 |
Brugia malayi | Carboxylesterase family protein | 0.0825 | 0.5836 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.0035 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0057 | 0.036 | 0.0348 |
Schistosoma mansoni | gliotactin | 0.0139 | 0.0946 | 0.0934 |
Loa Loa (eye worm) | carboxylesterase | 0.0825 | 0.5836 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0089 | 0.0583 | 0.32 |
Onchocerca volvulus | 0.0244 | 0.1692 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0825 | 0.5836 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0095 | 0.0625 | 0.1038 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0188 | 0.6972 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.036 | 0.2105 |
Onchocerca volvulus | 0.0139 | 0.0946 | 0.5475 | |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3618 | 0.361 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0825 | 0.5836 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0066 | 0.0054 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0825 | 0.5836 | 0.583 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.0126 | 0.0717 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0066 | 0.0054 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.024 | 0.2437 |
Onchocerca volvulus | 0.0139 | 0.0946 | 0.5475 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0188 | 0.0267 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0047 | 0.0117 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Trichomonas vaginalis | set domain proteins, putative | 0.0244 | 0.1692 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0057 | 0.036 | 0.0581 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0946 | 0.1574 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0188 | 0.0286 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0139 | 0.0946 | 0.5232 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0099 | 0.0654 | 0.3596 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.0005 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0013 | 0.0043 | 0.003 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0047 | 0.0044 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0066 | 0.0076 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0047 | 0.0252 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0229 | 0.4713 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0139 | 0.0946 | 0.0934 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.004 | 0.024 | 0.1275 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.024 | 0.1395 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.0946 | 0.1589 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0229 | 0.5852 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0225 | 0.9799 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0175 | 0.0246 |
Echinococcus granulosus | acetylcholinesterase | 0.0825 | 0.5836 | 0.583 |
Loa Loa (eye worm) | hypothetical protein | 0.0825 | 0.5836 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0175 | 0.0163 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0225 |
Echinococcus multilocularis | acetylcholinesterase | 0.0825 | 0.5836 | 0.583 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.024 | 0.2437 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0229 | 0.8952 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0047 | 1 |
Onchocerca volvulus | 0.0139 | 0.0946 | 0.5475 | |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0188 | 0.3671 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.036 | 0.2105 |
Echinococcus granulosus | dnaJ subfamily B | 0.0472 | 0.3314 | 0.3305 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.0304 | 0.0291 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.0035 |
Mycobacterium leprae | conserved hypothetical protein | 0.004 | 0.024 | 0.3546 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0085 | 0.0558 | 0.0546 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0139 | 0.0946 | 0.0934 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0162 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0825 | 0.5836 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0066 | 0.0076 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.025 | 0.1451 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0144 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.024 | 0.0358 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0089 | 0.0583 | 0.32 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0144 | 0.3176 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0138 | 0.0937 | 0.0926 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0175 | 0.6318 |
Schistosoma mansoni | hypothetical protein | 0.0472 | 0.3314 | 0.3305 |
Loa Loa (eye worm) | acetyltransferase | 0.0142 | 0.0966 | 0.1608 |
Brugia malayi | hypothetical protein | 0.0025 | 0.013 | 0.0186 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0013 | 0.0047 | 0.1319 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0013 | 0.0047 | 0.0372 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0188 | 0.0176 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0031 | 0.0019 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0047 | 0.0142 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0229 | 0.121 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0099 | 0.0654 | 0.3596 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0144 | 0.0822 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.036 | 0.2105 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.004 | 0.024 | 0.1275 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0201 | 0.0188 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0139 | 0.0946 | 0.5232 |
Brugia malayi | Pre-SET motif family protein | 0.0215 | 0.1481 | 0.251 |
Onchocerca volvulus | 0.004 | 0.024 | 0.1196 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0283 | 0.0271 |
Echinococcus multilocularis | snurportin 1 | 0.0355 | 0.2482 | 0.2472 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 55.69 um | PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT1 inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1263 (Confirmation screen (STAT1, 3X%INH)), 920 (Primary screen (STAT1, 1X%INH)), 862 (Primary screen (STAT3, 1X%INH)), 1303 (Counterscreen (NF-kappaB, 3X%INH)), 1803 (Summary (STAT1 inhibitors)), 1411 (Dose Response counterscreen (STAT1, 3XIC50)), 1310 (Counterscreen (STAT3, 3X%INH)), 1396 (Counterscreen (STAT3, 3X%INH))] | ChEMBL. | No reference |
IC50 (functional) | > 55.69 um | PUBCHEM_BIOASSAY: Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 920 (Primary screen (STAT1, 1X%INH)), 1310 (Counterscreen (STAT3, 3X%INH)), 1263 (Confirmation screen (STAT1, 3X%INH)), 862 (Primary screen (STAT3, 1X%INH)), 1303 (Counterscreen (NF-kappaB, 3X%INH)), 1803 (Summary (STAT1 inhibitors)), 1411 (Dose Response counterscreen (STAT1, 3XIC50)), 1396 (Dose Response (STAT3, 3XIC50))] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.