Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | propionate-CoA ligase | 0.0022 | 0.0278 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0076 | 0.1485 | 1 |
Onchocerca volvulus | 0.0022 | 0.0278 | 0.1873 | |
Echinococcus granulosus | tar DNA binding protein | 0.0125 | 0.2572 | 1 |
Brugia malayi | RNA binding protein | 0.0125 | 0.2572 | 0.2572 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1485 | 0.5773 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0022 | 0.0278 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0125 | 0.2572 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0076 | 0.1485 | 0.1485 |
Onchocerca volvulus | Putative nachr subunit | 0.0019 | 0.0191 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0278 | 0.0546 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Mycobacterium ulcerans | hypothetical protein | 0.0076 | 0.1485 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | ACC-1 protein | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.0278 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0076 | 0.1485 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0278 | 0.5 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0054 | 0.0983 | 0.6071 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1053 | 0.4094 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2572 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0054 | 0.0983 | 0.6071 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | TAR-binding protein | 0.0125 | 0.2572 | 0.2572 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0022 | 0.0278 | 0.0546 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0019 | 0.0191 | 0.0191 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0057 | 0.1053 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0022 | 0.0278 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1053 | 0.4094 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0076 | 0.1485 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0278 | 0.5 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | LGC-31 protein | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0022 | 0.0278 | 0.0546 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0057 | 0.1053 | 0.6617 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0019 | 0.0191 | 0.0744 |
Onchocerca volvulus | 0.0022 | 0.0278 | 0.1873 | |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0278 | 0.0546 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0076 | 0.1485 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0076 | 0.1485 | 1 |
Onchocerca volvulus | 0.0022 | 0.0278 | 0.1873 | |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0022 | 0.0278 | 0.1081 |
Loa Loa (eye worm) | RNA binding protein | 0.0125 | 0.2572 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0278 | 0.5 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0019 | 0.0191 | 0.0191 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0022 | 0.0278 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0278 | 0.1081 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.0278 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0019 | 0.0191 | 0.0744 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0278 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2572 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2572 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2572 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0125 | 0.2572 | 0.2572 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | AMP-binding enzyme family protein | 0.0076 | 0.1485 | 0.1485 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0019 | 0.0191 | 0.0744 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0019 | 0.0191 | 0.0744 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0278 | 0.0546 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0019 | 0.0191 | 0.0191 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0019 | 0.0191 | 0.0744 |
Onchocerca volvulus | 0.0022 | 0.0278 | 0.1873 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0076 | 0.1485 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0076 | 0.1485 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.1081 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1053 | 0.4094 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0076 | 0.1485 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0278 | 0.5 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | AMP-binding enzyme family protein | 0.0076 | 0.1485 | 0.1485 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0057 | 0.1053 | 0.5 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1053 | 0.4094 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0076 | 0.1485 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0022 | 0.0278 | 0.1081 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0278 | 0.0546 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2572 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1053 | 0.4094 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0278 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.0278 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0278 | 0.0546 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0019 | 0.0191 | 0.0191 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0076 | 0.1485 | 1 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0019 | 0.0191 | 0.0744 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0076 | 0.1485 | 1 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1485 | 0.5773 |
Brugia malayi | Cation transporter family protein | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | ACC-1 protein | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0054 | 0.0983 | 0.6071 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0019 | 0.0191 | 0.0191 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0022 | 0.0278 | 0.1081 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.1081 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0076 | 0.1485 | 1 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1485 | 0.5773 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0019 | 0.0191 | 0.0744 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0022 | 0.0278 | 0.1873 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0076 | 0.1485 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0054 | 0.0983 | 0.6071 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0057 | 0.1053 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0278 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0019 | 0.0191 | 0.0191 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0022 | 0.0278 | 0.5 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0019 | 0.0191 | 0.0744 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0076 | 0.1485 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0022 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0022 | 0.0278 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0019 | 0.0191 | 0.0191 |
Echinococcus multilocularis | tar DNA binding protein | 0.0125 | 0.2572 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0076 | 0.1485 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Brugia malayi | Cation transporter family protein | 0.0019 | 0.0191 | 0.0191 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0022 | 0.0278 | 0.1081 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0278 | 0.0278 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0019 | 0.0191 | 0.0744 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0019 | 0.0191 | 0.0744 |
Onchocerca volvulus | 0.0019 | 0.0191 | 0.1288 | |
Brugia malayi | Cation transporter family protein | 0.0019 | 0.0191 | 0.0191 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Schistosoma mansoni | nAChR subunit | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0057 | 0.1053 | 0.6421 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0076 | 0.1485 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0022 | 0.0278 | 0.0278 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0022 | 0.0278 | 0.0546 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | TAR-binding protein | 0.0125 | 0.2572 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0191 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0278 | 0.1081 |
Onchocerca volvulus | 0.0076 | 0.1485 | 1 | |
Echinococcus granulosus | glycine receptor subunit beta | 0.0019 | 0.0191 | 0.0744 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0022 | 0.0278 | 0.0546 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0076 | 0.1485 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (binding) | = 22.3872 um | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | ChEMBL. | No reference |
Potency (functional) | = 25.1189 um | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] | ChEMBL. | No reference |
Potency (binding) | = 25.1189 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.