Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0066 | 0.0066 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0794 | 0.1391 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0794 | 0.0794 |
Brugia malayi | CXXC zinc finger family protein | 0.0085 | 0.0608 | 0.1924 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0066 | 0.0052 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0066 | 0.0066 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0789 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0107 | 0.0789 | 0.2511 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0066 | 0.0175 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.021 | 0.0197 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0386 | 0.3109 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0066 | 0.0175 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0066 | 0.0175 |
Trichomonas vaginalis | ferritin, putative | 0.0017 | 0.0037 | 0.032 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.2693 | 0.2693 |
Onchocerca volvulus | 0.0014 | 0.0014 | 0.0026 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0052 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0794 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0066 | 0.0175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Echinococcus multilocularis | cpg binding protein | 0.009 | 0.0648 | 0.0635 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.021 | 0.2535 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0292 | 0.0904 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0017 | 0.0037 | 0.0295 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.021 | 0.2535 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0088 | 0.0977 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0066 | 0.0066 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0794 | 1 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0203 | 0.019 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0066 | 0.0052 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0108 | 0.0794 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0165 | 0.1272 | 0.126 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0066 | 0.0175 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0133 | 0.1544 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0037 | 0.021 | 0.255 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0066 | 0.0066 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0107 | 0.122 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0066 | 0.0066 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.021 | 0.064 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0052 |
Loa Loa (eye worm) | beta-lactamase | 0.0108 | 0.0794 | 0.2526 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0386 | 0.3109 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0292 | 0.3563 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.019 | 0.1476 | 0.4729 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.021 | 0.064 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0066 | 0.0693 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0176 | 0.029 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0052 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0066 | 0.0693 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0292 | 0.358 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.0292 | 0.0496 |
Onchocerca volvulus | 0.0014 | 0.0014 | 0.0026 | |
Onchocerca volvulus | 0.0014 | 0.0014 | 0.0026 | |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0037 | 0.0037 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0181 | 0.1403 | 0.1403 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0203 | 0.2445 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0066 | 0.0175 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0292 | 0.0904 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0066 | 0.0052 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0108 | 0.0794 | 0.1391 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0203 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0108 | 0.0794 | 0.0781 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0066 | 0.0052 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.1081 | 0.1081 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0789 | 0.0789 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0014 | 0.0014 | 0.0014 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Schistosoma mansoni | cpg binding protein | 0.009 | 0.0648 | 0.0648 |
Mycobacterium ulcerans | lipase LipD | 0.0108 | 0.0794 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0108 | 0.0794 | 0.1391 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0014 | 0.0014 | 0.0026 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0192 | 0.0318 |
Schistosoma mansoni | hypothetical protein | 0.1215 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0292 | 0.358 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0107 | 0.0761 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.0924 | 0.2946 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0037 | 0.021 | 0.021 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0192 | 0.2288 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.019 | 0.1476 | 0.4729 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0292 | 0.3563 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.2399 | 0.2389 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.021 | 0.2535 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0071 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | cpg binding protein | 0.009 | 0.0648 | 0.0648 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0037 | 0.021 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0026 | 0.0118 | 0.0104 |
Onchocerca volvulus | 0.0108 | 0.0794 | 1 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.0014 | 0.0007 |
Schistosoma mansoni | ran | 0.0021 | 0.0071 | 0.0071 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0037 |
Echinococcus granulosus | geminin | 0.0336 | 0.2693 | 0.2683 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0165 | 0.1272 | 0.126 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0014 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0037 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0066 | 0.0175 |
Onchocerca volvulus | 0.0108 | 0.0794 | 1 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0794 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0066 | 0.0175 |
Loa Loa (eye worm) | RNA binding protein | 0.0386 | 0.3109 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0066 | 0.0175 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0066 | 0.0175 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.021 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0192 | 0.0583 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.0789 | 0.0777 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0108 | 0.0794 | 0.1391 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0066 | 0.0175 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.2693 | 0.2693 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0292 | 0.0904 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0192 | 0.0583 |
Trichomonas vaginalis | helicase, putative | 0.0019 | 0.0059 | 0.0603 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0794 | 0.1391 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0071 | 0.0057 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0085 | 0.0608 | 0.1924 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0133 | 0.0133 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0133 | 0.6651 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0017 | 0.0037 | 0.0295 |
Schistosoma mansoni | tar DNA-binding protein | 0.0386 | 0.3109 | 0.3109 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0066 | 0.0052 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0037 | 0.0037 |
Echinococcus multilocularis | tar DNA binding protein | 0.0386 | 0.3109 | 0.3099 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0107 | 0.0308 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0107 | 0.122 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | tar DNA-binding protein | 0.0386 | 0.3109 | 0.3109 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0108 | 0.0794 | 0.1391 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0037 | 0.021 | 0.0197 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0203 | 0.246 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.1081 | 0.1081 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0066 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0107 | 0.5235 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0037 | 0.0037 |
Trichomonas vaginalis | esterase, putative | 0.0108 | 0.0794 | 1 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0071 | 0.3186 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0794 | 0.1391 |
Brugia malayi | beta-lactamase | 0.0108 | 0.0794 | 0.2526 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.019 | 0.1476 | 0.1465 |
Onchocerca volvulus | 0.0047 | 0.0292 | 0.358 | |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0021 | 0.0074 | 0.0061 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0165 | 0.1272 | 0.4069 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0066 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0133 | 0.0119 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0386 | 0.3109 | 0.3109 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0066 | 0.0052 |
Brugia malayi | RNA binding protein | 0.0386 | 0.3109 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0292 | 0.3563 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0108 | 0.0794 | 0.0781 |
Brugia malayi | TAR-binding protein | 0.0386 | 0.3109 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0794 | 0.0794 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0021 | 0.0074 | 0.0074 |
Echinococcus granulosus | tar DNA binding protein | 0.0386 | 0.3109 | 0.3099 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0108 | 0.0794 | 0.2526 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.1476 | 0.1476 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0809 | 0.6622 | 0.6618 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0794 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0037 | 0.0037 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.0292 | 0.3563 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0162 | 0.1242 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0037 |
Schistosoma mansoni | tar DNA-binding protein | 0.0386 | 0.3109 | 0.3109 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0021 | 0.0074 | 0.0061 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0088 | 0.0977 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Onchocerca volvulus | 0.0096 | 0.0693 | 0.8705 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.0292 | 0.3563 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0071 | 0.0753 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0088 | 0.0977 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0789 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.021 | 0.2535 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0108 | 0.0794 | 0.1391 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.021 | 0.2535 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0794 | 0.2526 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.0924 | 0.2946 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0071 | 0.0729 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0292 | 0.0904 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0203 | 0.2445 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0165 | 0.1272 | 0.4069 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0176 | 0.029 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0292 | 0.0904 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0108 | 0.0794 | 0.1391 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1215 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0066 | 0.0052 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0107 | 0.0308 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0794 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.0565 | 0.1785 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.1476 | 0.1476 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0066 | 0.0052 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0014 | 0.0026 |
Mycobacterium leprae | conserved hypothetical protein | 0.0108 | 0.0794 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0066 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0133 | 0.039 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0789 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0066 | 0.0175 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0026 | 0.0115 | 0.0333 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0192 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0203 | 0.2445 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0066 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0192 | 0.0583 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0017 | 0.0037 | 0.0041 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0292 | 0.3601 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0203 | 0.246 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0088 | 0.0977 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0071 | 0.0463 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0071 | 0.0753 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.021 | 0.2535 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.019 | 0.1476 | 0.1465 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0037 | 0.021 | 0.2535 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0066 | 0.0175 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.021 | 0.0197 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.2399 | 0.2389 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0088 | 0.0977 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0014 | 0.0026 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0017 | 0.0037 | 0.0295 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0071 | 0.0753 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2399 | 0.2399 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0133 | 0.1544 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.0789 | 0.0777 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0014 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0108 | 0.0794 | 0.2526 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0037 | 0.0023 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0108 | 0.0794 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0133 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0292 | 0.0904 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0292 | 0.3563 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.0292 | 0.0496 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0014 | 0.0014 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Schistosoma mansoni | tar DNA-binding protein | 0.0386 | 0.3109 | 0.3109 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0176 | 0.029 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0014 | 0.0026 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0107 | 0.122 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0066 | 0.0693 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0021 | 0.0074 | 0.0061 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.0292 | 0.3601 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.019 | 0.1476 | 0.1465 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0088 | 0.0983 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0037 | 0.0023 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0066 | 0.0066 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.0924 | 0.2946 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.0789 | 0.0789 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0066 | 0.0175 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0026 | 0.0118 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0192 | 0.0583 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0037 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0789 | 1 |
Echinococcus granulosus | cpg binding protein | 0.009 | 0.0648 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0794 | 0.2526 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0071 | 0.0057 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0066 | 0.0175 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0107 | 0.122 |
Loa Loa (eye worm) | histone methyltransferase | 0.0026 | 0.0118 | 0.0342 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0203 | 0.0618 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0059 | 0.0603 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0133 | 0.0967 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0107 | 0.5235 |
Loa Loa (eye worm) | oxidoreductase | 0.0014 | 0.0014 | 0.0007 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0192 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0203 | 0.0618 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0066 | 0.0052 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Onchocerca volvulus | 0.0085 | 0.0608 | 0.7616 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0108 | 0.0794 | 1 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0017 | 0.0037 | 0.0041 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0052 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.2399 | 0.7709 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0292 | 0.3563 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0066 | 0.0175 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.0292 | 0.3563 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.0014 | 0.0007 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0133 | 0.0119 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0203 | 0.0203 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0203 | 0.2445 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0037 | 0.5 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0037 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0066 | 0.0175 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0107 | 0.1198 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Toxoplasma gondii | ABC1 family protein | 0.0108 | 0.0794 | 0.6353 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0108 | 0.0794 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0066 | 0.0052 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0071 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0014 | 0.0007 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0066 | 0.0175 |
Schistosoma mansoni | cpg binding protein | 0.0085 | 0.0608 | 0.0608 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0292 | 0.358 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0133 | 0.1522 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0066 | 0.0175 |
Mycobacterium ulcerans | hypothetical protein | 0.0108 | 0.0794 | 1 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0037 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0066 | 0.0175 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0071 | 0.019 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0033 | 0.0069 |
Loa Loa (eye worm) | TAR-binding protein | 0.0386 | 0.3109 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0688 | 0.5621 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0203 | 0.019 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0071 | 0.0757 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0292 | 0.3601 |
Mycobacterium ulcerans | beta-lactamase | 0.0108 | 0.0794 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0203 | 0.2445 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0037 | 0.021 | 0.021 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0176 | 0.029 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0014 | 0.0007 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0794 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0066 | 0.0052 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0021 | 0.0074 | 0.0061 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0108 | 0.0794 | 0.1391 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0192 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0192 | 0.0583 |
Echinococcus multilocularis | geminin | 0.0336 | 0.2693 | 0.2683 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0794 | 1 |
Onchocerca volvulus | 0.0108 | 0.0794 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.1476 | 0.1476 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0203 | 0.2445 |
Schistosoma mansoni | ran | 0.0021 | 0.0071 | 0.0071 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0037 | 0.0023 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0203 | 0.2445 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.0292 | 0.3563 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.0292 | 0.3563 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0071 | 0.019 |
Onchocerca volvulus | 0.002 | 0.0066 | 0.0693 | |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0037 | 0.021 | 0.0197 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0794 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.019 | 0.1476 | 0.1465 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.021 | 0.0197 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0066 | 0.0175 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0059 | 0.0603 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0203 | 0.2445 |
Mycobacterium leprae | Probable lipase LipE | 0.0108 | 0.0794 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0165 | 0.1272 | 0.126 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0066 | 0.0066 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0066 | 0.0052 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0794 | 0.2526 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0014 | 0.0007 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
AC50 (functional) | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active | ChEMBL. | No reference | |
AC50 (functional) | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active | ChEMBL. | No reference | |
AC50 (functional) | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active | ChEMBL. | No reference | |
AC50 (functional) | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active | ChEMBL. | No reference | |
AC50 (functional) | = 31.6227766 uM | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active | ChEMBL. | No reference |
Potency (functional) | = 25.1189 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 29.9068 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | ChEMBL. | No reference |
Potency (binding) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.