Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.258 | 0.8135 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.3172 | 0.3172 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3172 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.3172 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.258 | 0.8135 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.258 | 0.8135 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.3172 | 0.3172 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.3172 | 0.3172 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.3172 | 0.3172 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.258 | 0.258 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.258 | 0.258 |
Onchocerca volvulus | 0.0175 | 1 | 1 | |
Brugia malayi | RNA binding protein | 0.0063 | 0.3172 | 0.3172 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.258 | 0.8135 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3172 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3172 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.258 | 0.8135 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.258 | 0.8135 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.3172 | 0.3172 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3172 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3172 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.3172 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.258 | 0.8135 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.