Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1192 | 0.0986 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0086 | 0.3314 | 0.7911 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0089 | 0.3447 | 0.8837 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.4751 | 0.5433 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0014 | 0.0229 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1608 | 0.1839 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0107 | 0.4189 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.8744 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.1608 | 0.323 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Schistosoma mansoni | transient receptor potential channel | 0.0107 | 0.4189 | 0.8412 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0094 | 0.0108 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.4204 | 0.4807 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1189 | 0.1359 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.007 | 0.2653 | 0.6334 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0103 | 0.4038 | 0.9639 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0234 | 0.0421 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2614 | 0.5248 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0496 | 0.0273 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0086 | 0.3314 | 0.379 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0234 | 0.0421 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.1608 | 0.4135 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.2614 | 0.6238 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.1192 | 0.2846 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0496 | 0.1183 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.001 | 0.0076 | 0.0087 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0094 | 0.0108 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.001 | 0.0076 | 0.0087 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0014 | 0.0229 | 0.1218 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0496 | 0.0751 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.4189 | 0.4791 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.007 | 0.2653 | 0.6334 |
Mycobacterium tuberculosis | Probable reductase | 0.0089 | 0.3447 | 0.8837 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0957 | 0.1921 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0957 | 0.2283 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0496 | 0.0567 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0094 | 0.0108 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0107 | 0.4189 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.4204 | 0.4807 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0682 | 0.4171 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1093 | 0.2194 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0099 | 0.3871 | 1 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.1192 | 0.2122 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.2614 | 0.2989 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0107 | 0.4189 | 0.8412 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0496 | 0.5879 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.1027 | 0.2564 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0094 | 0.0225 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0094 | 0.0108 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.1316 | 0.2985 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0094 | 0.0189 |
Schistosoma mansoni | kinase | 0.0049 | 0.175 | 0.3513 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.1608 | 0.4135 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.004 | 0.134 | 0.3198 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0094 | 0.0189 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0094 | 0.0225 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0097 | 0.3779 | 0.4322 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0099 | 0.3871 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0094 | 0.0225 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0014 | 0.0229 | 0.0407 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1192 | 0.2122 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0094 | 0.0189 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.1027 | 0.2564 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.1608 | 0.3839 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0496 | 0.1128 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0097 | 0.3779 | 0.7588 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1093 | 0.125 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0957 | 0.1921 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0097 | 0.3779 | 0.372 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0014 | 0.0229 | 0.0407 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2614 | 0.5248 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.8744 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0496 | 0.1183 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0089 | 0.3447 | 0.8672 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.1093 | 0.125 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0682 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0496 | 0.5879 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.1316 | 0.3345 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.1608 | 0.1839 |
Brugia malayi | RNA binding protein | 0.007 | 0.2614 | 0.2989 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0094 | 0.0189 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0089 | 0.3447 | 0.8837 |
Brugia malayi | glutathione reductase | 0.0039 | 0.1316 | 0.1505 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2502 | 0.2862 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.1695 | 0.1501 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0094 | 0.0108 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0024 | 0.0682 | 0.488 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0957 | 0.1094 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.1093 | 0.2608 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0094 | 0.0189 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.1192 | 0.3011 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0957 | 0.1921 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.1093 | 0.2608 |
Trypanosoma brucei | polo-like protein kinase | 0.0097 | 0.3779 | 1 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1053 | 0.1204 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0496 | 0.0273 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0682 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0094 | 0.0189 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.2764 | 0.3161 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1093 | 0.2194 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.4204 | 0.4807 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0094 | 0.0108 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0032 | 0.102 | 0.1597 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0089 | 0.3447 | 0.8837 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0229 | 0.2495 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0014 | 0.0229 | 0.1218 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.1053 | 0.1204 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.1608 | 0.3839 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0234 | 0.0421 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0094 | 0.0108 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.1093 | 0.2608 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0024 | 0.0682 | 1 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.1192 | 0.9 |
Schistosoma mansoni | rotamase | 0.0033 | 0.1053 | 0.2114 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0094 | 0.0189 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.1608 | 0.4135 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0957 | 0.6692 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0094 | 0.0225 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0103 | 0.4038 | 0.9639 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0094 | 0.0225 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0099 | 0.3871 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0094 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0094 | 0.0189 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.004 | 0.134 | 0.3198 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.134 | 0.1532 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.1192 | 0.8862 |
Leishmania major | trypanothione reductase | 0.0039 | 0.1316 | 0.3345 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0094 | 0.0108 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.1316 | 0.3345 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.1027 | 0.7664 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0957 | 0.1094 |
Onchocerca volvulus | 0.0086 | 0.3314 | 0.3251 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0094 | 0.0225 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0094 | 0.0189 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0097 | 0.3779 | 0.902 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.2764 | 0.3161 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0094 | 0.0225 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0094 | 0.0225 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0097 | 0.3779 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.2614 | 0.2989 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.102 | 0.0809 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.1192 | 0.1364 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1192 | 0.0986 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0014 | 0.0229 | 0.0407 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.102 | 0.2544 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0229 | 0.0262 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0097 | 0.3779 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.102 | 0.7606 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0024 | 0.0682 | 1 |
Brugia malayi | TAR-binding protein | 0.007 | 0.2614 | 0.2989 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0682 | 0.1633 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.1695 | 0.1501 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0099 | 0.3871 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.007 | 0.2653 | 0.5328 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0024 | 0.0682 | 0.1633 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0957 | 0.7095 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0496 | 0.1128 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0086 | 0.3314 | 0.7911 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0094 | 0.0189 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0957 | 0.2283 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0229 | 0.0547 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.1093 | 0.2608 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.102 | 0.2544 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.004 | 0.1338 | 0.3195 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0014 | 0.0229 | 0.0407 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.4751 | 0.5433 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.4751 | 0.5433 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.1093 | 0.125 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.1192 | 0.2846 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.1316 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0094 | 0.0225 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0094 | 0.0189 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0094 | 0.0225 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Schistosoma mansoni | transient receptor potential channel | 0.007 | 0.2653 | 0.5328 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0094 | 0.0189 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0234 | 0.0421 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.2614 | 0.6238 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Onchocerca volvulus | 0.0031 | 0.0957 | 0.0871 | |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0682 | 0.4171 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.1192 | 0.1364 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0094 | 0.0225 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1192 | 0.0986 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0094 | 0.0225 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0094 | 0.0225 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.1053 | 0.2513 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.102 | 0.2544 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.2614 | 0.2989 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0036 | 0.1192 | 0.8862 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0097 | 0.3779 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0094 | 0.0225 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0496 | 0.1183 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0094 | 0.0108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0957 | 0.1921 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0496 | 0.1128 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.1316 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2614 | 0.5248 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.1316 | 0.1505 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0024 | 0.0682 | 0.1245 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0496 | 0.0732 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0094 | 0.0225 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0094 | 0.0108 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0496 | 0.1183 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0094 | 0.0108 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.1316 | 0.1505 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0089 | 0.3447 | 0.8837 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0094 | 0.0225 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0094 | 0.0108 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.1093 | 0.125 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.1093 | 0.2608 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.1192 | 0.3011 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1093 | 0.2194 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.004 | 0.1338 | 0.3195 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.007 | 0.2653 | 0.6334 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.4204 | 0.4807 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0234 | 0.0421 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0496 | 0.0732 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0094 | 0.0108 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0014 | 0.0229 | 0.0407 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0496 | 0.0995 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.1316 | 1 |
Giardia lamblia | Kinase, PLK | 0.0097 | 0.3779 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.2614 | 0.2989 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0086 | 0.3314 | 0.6655 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1053 | 0.0843 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0094 | 0.0108 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0097 | 0.3779 | 0.4322 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0014 | 0.0229 | 0.0407 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.3779 | 0.3633 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.1053 | 0.2513 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0909 | 0.2169 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0094 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.3314 | 0.379 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0229 | 0.2495 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0957 | 0.2283 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.1192 | 0.2394 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0682 | 0.0569 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0496 | 0.0567 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0496 | 0.0995 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0094 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.2764 | 0.5549 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0094 | 0.0225 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0496 | 0.1128 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.1316 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0094 | 0.0108 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0094 | 0.0108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0496 | 0.1128 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0094 | 0.0108 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0097 | 0.3779 | 0.902 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.1192 | 0.3011 |
Brugia malayi | Transient-receptor-potential like protein | 0.004 | 0.134 | 0.1532 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.1093 | 0.2608 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0089 | 0.3447 | 0.8837 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0229 | 0.046 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0097 | 0.3779 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.102 | 0.2544 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1093 | 0.2194 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0496 | 0.1128 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.007 | 0.2653 | 0.6334 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2614 | 0.5248 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0024 | 0.0682 | 0.488 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2614 | 0.5248 |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.1192 | 0.3011 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0229 | 0.0547 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.1316 | 0.1505 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0682 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.1316 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0229 | 0.0407 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.1053 | 0.0843 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 79.4328 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.