Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | jumonji domain containing protein | 0.0048 | 0.2943 | 0.2766 |
Echinococcus granulosus | jumonji domain containing protein | 0.0048 | 0.2943 | 0.2766 |
Echinococcus granulosus | peregrin | 0.0037 | 0.178 | 0.1574 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.1476 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0045 | 0.2651 | 0.1897 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.321 | 0.4709 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0627 | 0.0391 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.1476 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0381 | 0.0559 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.4153 | 0.6091 |
Schistosoma mansoni | jumonji domain containing protein | 0.0089 | 0.7478 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0034 | 0.1476 | 0.1262 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1476 | 0.1702 |
Brugia malayi | jmjC domain containing protein | 0.0044 | 0.251 | 0.1741 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0627 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.6818 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0113 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0381 | 0.0188 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.1476 | 0.0601 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.7367 | 0.7097 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.5402 | 0.5286 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.5862 | 0.7765 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0071 | 0.5465 | 0.8016 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.5402 | 0.5286 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0034 | 0.1476 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1476 | 0.2165 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.1476 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.2347 | 0.2155 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2965 | 0.4348 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0627 | 0.0527 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.2347 | 0.2155 |
Echinococcus multilocularis | peregrin | 0.0037 | 0.178 | 0.1574 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0044 | 0.251 | 0.2321 |
Onchocerca volvulus | Alhambra homolog | 0.0034 | 0.1476 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0044 | 0.251 | 0.3681 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0042 | 0.2264 | 0.207 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0034 | 0.1476 | 0.1702 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0044 | 0.251 | 0.3131 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0044 | 0.251 | 0.3131 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0034 | 0.1476 | 0.1262 |
Plasmodium falciparum | phd finger protein, putative | 0.0034 | 0.1476 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.178 | 0.0937 |
Giardia lamblia | PHD finger protein 15 | 0.0034 | 0.1476 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.266 | 0.3902 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0113 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.