Detailed information for compound 1209882

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 516.752 | Formula: C32H52O5
  • H donors: 3 H acceptors: 4 LogP: 5.49 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)OC[C@]12CC[C@@]3([C@]([C@H]2[C@@H](C[C@H]1C(C)C)O)(C)CC=C1[C@H]3[C@@H](O)C[C@@H]2[C@]1(C)CC[C@@H](C2(C)C)O)C
  • InChi: 1S/C32H52O5/c1-18(2)21-15-23(35)27-31(8)12-9-20-26(30(31,7)13-14-32(21,27)17-37-19(3)33)22(34)16-24-28(4,5)25(36)10-11-29(20,24)6/h9,18,21-27,34-36H,10-17H2,1-8H3/t21-,22-,23+,24-,25-,26-,27+,29+,30-,31+,32+/m0/s1
  • InChiKey: QIFUZQYPSMCPOR-CRBXCGNKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0417 0.0469
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0827 0.0944
Onchocerca volvulus 0.0045 0.0304 0.0273
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0512 0.0577
Trichomonas vaginalis mercuric reductase, putative 0.0057 0.0421 0.0391
Trichomonas vaginalis inositol monophosphatase, putative 0.0115 0.102 0.0992
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0042 0.0266 0.0304
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.113 0.1225
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0087 0.0732 0.0791
Trichomonas vaginalis set domain proteins, putative 0.0992 1 1
Echinococcus granulosus para nitrobenzyl esterase 0.0045 0.0304 0.0312
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0029 0.0023
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0568 0.0589
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Loa Loa (eye worm) hypothetical protein 0.0071 0.056 0.0632
Plasmodium vivax vivapain-2 0.0019 0.0032 0.007
Toxoplasma gondii cytochrome p450 superfamily protein 0.0038 0.0227 0.0618
Echinococcus multilocularis RUN 0.0041 0.0262 0.0268
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0343 0.3353 0.3516
Brugia malayi Pre-SET motif family protein 0.0126 0.113 0.1288
Loa Loa (eye worm) hypothetical protein 0.0126 0.113 0.1282
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0057 0.0421 0.409
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0568 0.5534
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0304 0.2238
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0017 0.0011
Onchocerca volvulus Huntingtin homolog 0.0126 0.1126 0.1097
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0038 0.0227 0.2176
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.102 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1806 0.1891
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0266 0.0272
Echinococcus granulosus lysine specific demethylase 6a 0.0043 0.0283 0.029
Onchocerca volvulus 0.0057 0.0417 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Schistosoma mansoni cpg binding protein 0.006 0.045 0.0484
Echinococcus multilocularis lysine specific demethylase 6a 0.0043 0.0283 0.029
Echinococcus granulosus snurportin 1 0.0361 0.3537 0.371
Schistosoma mansoni cytochrome P450 0.0038 0.0227 0.0241
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0184 0.0498
Schistosoma mansoni hypothetical protein 0.0097 0.0827 0.0895
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.113 0.118
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0032 0.007
Echinococcus granulosus thioredoxin glutathione reductase 0.01 0.0861 0.0898
Loa Loa (eye worm) cytochrome P450 0.0038 0.0227 0.0252
Loa Loa (eye worm) hypothetical protein 0.0305 0.2965 0.3377
Loa Loa (eye worm) hypothetical protein 0.0042 0.0266 0.0296
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0089 0.0813
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0057 0.0421 0.048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0827 0.0862
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.1334 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0266 0.2558
Trypanosoma cruzi trypanothione reductase, putative 0.01 0.0861 0.843
Echinococcus multilocularis neuropeptide receptor A26 0.0945 0.9525 1
Brugia malayi PHD-finger family protein 0.0032 0.0163 0.0186
Loa Loa (eye worm) carboxylesterase 0.0045 0.0304 0.0339
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0184 0.1754
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0858 0.0979
Loa Loa (eye worm) hypothetical protein 0.0034 0.0184 0.0203
Brugia malayi Doublecortin family protein 0.0041 0.0262 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Loa Loa (eye worm) ctsf protein 0.0019 0.0032 0.0029
Loa Loa (eye worm) Smad1 0.0017 0.0017 0.0012
Schistosoma mansoni lipoxygenase 0.0173 0.1611 0.1749
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0269 0.2595 0.2823
Loa Loa (eye worm) jmjC domain-containing protein 0.018 0.1683 0.1914
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0057 0.0421 0.1162
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.102 0.2841
Loa Loa (eye worm) hypothetical protein 0.0145 0.1326 0.1506
Brugia malayi hypothetical protein 0.0041 0.0262 0.0299
Brugia malayi Thioredoxin reductase 0.01 0.0861 0.0982
Echinococcus multilocularis 0.0038 0.0227 0.0232
Brugia malayi Importin beta-1 subunit 0.0034 0.0184 0.021
Trypanosoma brucei trypanothione reductase 0.01 0.0861 0.843
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.013 0.1217
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0365 0.3574 1
Brugia malayi Pre-SET motif family protein 0.0872 0.8768 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0227 0.2176
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1806 0.1963
Echinococcus multilocularis thioredoxin glutathione reductase 0.01 0.0861 0.0898
Echinococcus multilocularis GPCR, family 2 0.0097 0.0827 0.0862
Schistosoma mansoni hypothetical protein 0.0806 0.8092 0.8819
Echinococcus granulosus carboxylesterase 5A 0.0269 0.2595 0.2719
Echinococcus multilocularis peregrin 0.0091 0.0769 0.0801
Schistosoma mansoni hypothetical protein 0.0911 0.9175 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.1806 0.206
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0266 0.0272
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0576 0.5619
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0119 0.0087
Schistosoma mansoni hypothetical protein 0.0029 0.013 0.0135
Plasmodium falciparum glutathione reductase 0.0057 0.0421 0.1162
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.1334 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0166 0.154 0.1673
Entamoeba histolytica heat shock transcription factor, putative 0.0106 0.0921 0.31
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0732 0.2032
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1806 0.1891
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0283 0.0316
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0032 0.007
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0057 0.0421 0.1752
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0119 0.0087
Brugia malayi MH2 domain containing protein 0.0257 0.2469 0.2816
Mycobacterium tuberculosis Carboxylesterase LipT 0.0045 0.0304 0.2238
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.107 0.1117
Echinococcus granulosus JmjC domain containing protein 4 0.0043 0.0283 0.029
Echinococcus multilocularis para nitrobenzyl esterase 0.0045 0.0304 0.0312
Onchocerca volvulus 0.0045 0.0304 0.0273
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0266 0.0616
Echinococcus multilocularis cpg binding protein 0.006 0.045 0.0466
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.002
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0247 0.0752
Schistosoma mansoni ran 0.0025 0.0093 0.0094
Brugia malayi jmjC domain containing protein 0.0166 0.154 0.1757
Schistosoma mansoni cpg binding protein 0.006 0.045 0.0484
Loa Loa (eye worm) transcription factor SMAD2 0.0257 0.2469 0.2811
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Schistosoma mansoni protein phosphatase 2C 0.0043 0.0283 0.0302
Giardia lamblia NADH oxidase lateral transfer candidate 0.0057 0.0421 0.1169
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.1334 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0266 0.0235
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0262 0.0268
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0321 0.0343
Echinococcus multilocularis lysine specific demethylase 5A 0.0163 0.1507 0.1577
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0568 0.3075
Schistosoma mansoni transient receptor potential channel 0.0074 0.0599 0.0646
Echinococcus granulosus BC026374 protein S09 family 0.0045 0.0304 0.0312
Schistosoma mansoni jumonji/arid domain-containing protein 0.0166 0.154 0.1673
Brugia malayi HSF-type DNA-binding domain containing protein 0.0106 0.0921 0.1051
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0032 0.0026
Echinococcus multilocularis short transient receptor potential channel 6 0.0074 0.0599 0.0622
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0316
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1806 0.1963
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0089 0.0813
Schistosoma mansoni hypothetical protein 0.0097 0.0827 0.0895
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0032 0.007
Brugia malayi Carboxylesterase family protein 0.0045 0.0304 0.0346
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0361 0.3537 0.403
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0032 0.0026
Leishmania major cathepsin L-like protease 0.0072 0.0576 0.5619
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0038 0.0227 0.1662
Plasmodium falciparum phd finger protein, putative 0.0087 0.0732 0.2032
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2901 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.113 0.1225
Echinococcus granulosus cpg binding protein 0.006 0.045 0.0466
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0184 0.1754
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0283 0.2727
Echinococcus multilocularis inositol monophosphatase 1 0.0115 0.102 0.1065
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0038 0.0227 0.1662
Echinococcus multilocularis muscleblind protein 1 0.0145 0.1326 0.1387
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0512 0.508 0.5791
Loa Loa (eye worm) cytochrome P450 family protein 0.008 0.0658 0.0744
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0247 0.055
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0057 0.0421 0.409
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0266 0.0303
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.1357 0.1473
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0057 0.0421 0.1752
Schistosoma mansoni rab6-interacting 0.0041 0.0262 0.0278
Echinococcus granulosus geminin 0.0911 0.9175 0.9633
Onchocerca volvulus Alhambra homolog 0.0087 0.0732 0.0702
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0057 0.0421 0.1752
Loa Loa (eye worm) glutathione reductase 0.01 0.0861 0.0975
Echinococcus multilocularis transient receptor potential ion channel A 0.0109 0.095 0.0991
Schistosoma mansoni jumonji domain containing protein 0.0284 0.2751 0.2994
Loa Loa (eye worm) hypothetical protein 0.0126 0.1126 0.1277
Loa Loa (eye worm) fibroinase 0.0019 0.0032 0.0029
Leishmania major hypothetical protein, conserved 0.0043 0.0283 0.2727
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0057 0.0421 0.0436
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Brugia malayi AF-10 protein 0.0029 0.013 0.0148
Schistosoma mansoni phd/f-box containing protein 0.0043 0.0283 0.0302
Brugia malayi hypothetical protein 0.0045 0.0304 0.0346
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0827 0.0862
Echinococcus granulosus Smad4 0.0017 0.0017 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Onchocerca volvulus 0.0045 0.0304 0.0273
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.013 0.0346
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0038 0.0227 0.1662
Entamoeba histolytica Ran family GTPase 0.0025 0.0093 0.0213
Loa Loa (eye worm) hypothetical protein 0.0112 0.0988 0.112
Brugia malayi hypothetical protein 0.0126 0.1126 0.1284
Loa Loa (eye worm) PHD-finger family protein 0.0087 0.0732 0.0828
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0038 0.0227 0.1662
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0283 0.0316
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0568 0.4226
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0032 0.0027
Echinococcus granulosus acetylcholinesterase 0.0269 0.2595 0.2719
Brugia malayi Cytochrome P450 family protein 0.008 0.0658 0.0751
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.0165 0.1527 0.1735
Loa Loa (eye worm) hypothetical protein 0.0209 0.1976 0.2247
Trichomonas vaginalis ran, putative 0.0025 0.0093 0.0061
Brugia malayi Carboxylesterase family protein 0.0045 0.0304 0.0346
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0089 0.0813
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0038 0.0227 0.1662
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0285 0.0779
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0057 0.0421 0.409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Loa Loa (eye worm) cysteine protease 0.0019 0.0032 0.0029
Echinococcus granulosus TRP transient receptor potential channel 0.0042 0.0266 0.0272
Onchocerca volvulus 0.01 0.0858 0.0829
Brugia malayi follicle stimulating hormone receptor 0.0512 0.508 0.5794
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0017 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0262 0.0268
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.113 0.118
Leishmania major importin beta-1 subunit, putative 0.0027 0.0119 0.1107
Schistosoma mansoni hypothetical protein 0.0209 0.1976 0.2148
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0568 0.1572
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0103 0.0896 0.6046
Toxoplasma gondii PHD-finger domain-containing protein 0.0087 0.0732 0.2032
Echinococcus granulosus dnaJ subfamily B 0.0806 0.8092 0.8495
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Echinococcus multilocularis survival motor neuron protein 1 0.0488 0.484 0.5078
Schistosoma mansoni loxhd1 0.0041 0.0262 0.0278
Schistosoma mansoni neuroligin 3 (S09 family) 0.0045 0.0304 0.0324
Echinococcus multilocularis transient receptor potential gamma protein 0.0112 0.0988 0.1031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0227 0.2176
Brugia malayi Cytochrome P450 family protein 0.0066 0.0512 0.0584
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0057 0.0421 0.1162
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0093 0.0851
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0285 0.0254
Leishmania major cathepsin L-like protease 0.0019 0.0032 0.0247
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0045 0.0304 0.0273
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0568 0.0612
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0418 0.4061
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0304 0.2238
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0512 0.0577
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0266 0.2558
Loa Loa (eye worm) jmjC domain-containing protein 0.0166 0.154 0.1751
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0247 0.0675
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0057 0.0421 0.1752
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1806 0.1963
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0025 0.0093 0.0242
Schistosoma mansoni ran 0.0025 0.0093 0.0094
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0115 0.102 0.2841
Plasmodium vivax glutathione reductase, putative 0.01 0.0861 0.2395
Echinococcus multilocularis acetylcholinesterase 0.0269 0.2595 0.2719
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.1314 0.1374
Leishmania major cathepsin L-like protease 0.0019 0.0032 0.0247
Schistosoma mansoni transient receptor potential channel 0.0074 0.0599 0.0646
Echinococcus multilocularis jumonji domain containing protein 0.0121 0.1082 0.113
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0576 0.5619
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0126 0.1126 0.1277
Echinococcus granulosus lysine specific demethylase 5A 0.0166 0.154 0.1611
Schistosoma mansoni hypothetical protein 0.0041 0.0262 0.0278
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0057 0.0421 0.409
Leishmania major cytochrome p450-like protein 0.0038 0.0227 0.2176
Echinococcus multilocularis PHD finger protein rhinoceros 0.0087 0.0732 0.0762
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0057 0.0421 0.1162
Schistosoma mansoni rab6-interacting 0.0041 0.0262 0.0278
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0827 0.0862
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0043 0.0283 0.0302
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0247 0.2374 0.2487
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Brugia malayi jmjC domain containing protein 0.0043 0.0283 0.0323
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0266 0.0272
Echinococcus multilocularis cysteine protease 0.0019 0.0032 0.0026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0872 0.8768 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0093 0.0099
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.113 0.3147
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0365 0.3574 1
Giardia lamblia PHD finger protein 15 0.0087 0.0732 0.2275
Brugia malayi latrophilin 2 splice variant baaae 0.0209 0.1976 0.2253
Trichomonas vaginalis glutathione reductase, putative 0.0057 0.0421 0.0391
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0266 0.0816
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0093 0.0242
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0029 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0266 0.0235
Schistosoma mansoni gliotactin 0.0045 0.0304 0.0324
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0042 0.0266 0.0304
Leishmania major hypothetical protein, conserved 0.0025 0.0089 0.0813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0266 0.0272
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Brugia malayi Smad1 0.0017 0.0017 0.002
Echinococcus multilocularis jumonji domain containing 1A 0.0043 0.0283 0.029
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0247 0.2374 0.2487
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.2901 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0032 0.0029
Echinococcus granulosus jumonji domain containing 1A 0.0043 0.0283 0.029
Brugia malayi hypothetical protein 0.0488 0.484 0.552
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1806 0.1891
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0304 0.0324
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0017 0.0012
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0042 0.0266 0.0272
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0093 0.0851
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0038 0.0227 0.1662
Echinococcus granulosus phd:f box containing protein 0.0043 0.0283 0.029
Brugia malayi hypothetical protein 0.0041 0.0262 0.0299
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0262 0.0268
Echinococcus granulosus neuropeptide receptor A26 0.0945 0.9525 1
Plasmodium falciparum importin beta, putative 0.0034 0.0184 0.0498
Brugia malayi PHD-finger family protein 0.0087 0.0732 0.0835
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.1357 0.1547
Schistosoma mansoni inositol monophosphatase 0.0115 0.102 0.1106
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0038 0.0227 0.1662
Onchocerca volvulus 0.0126 0.113 0.1101
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0038 0.0227 0.1662
Plasmodium vivax importin-beta 2, putative 0.0034 0.0184 0.0498
Brugia malayi jmjC domain containing protein 0.0043 0.0283 0.0323
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0066 0.0512 0.2574
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0032 0.0029
Echinococcus granulosus survival motor neuron protein 1 0.0488 0.484 0.5078
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0115 0.102 0.7166
Leishmania major cathepsin L-like protease 0.0019 0.0032 0.0247
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.013 0.1217
Echinococcus granulosus cathepsin l1 0.0019 0.0032 0.0026
Loa Loa (eye worm) hypothetical protein 0.0488 0.484 0.5517
Brugia malayi Bromodomain containing protein 0.0091 0.0769 0.0877
Echinococcus multilocularis smad 0.0017 0.0017 0.0011
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0038 0.0227 0.2176
Brugia malayi Transient-receptor-potential like protein 0.0042 0.0266 0.0303
Brugia malayi Cytochrome P450 family protein 0.0038 0.0227 0.0259
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0266 0.0272
Echinococcus granulosus short transient receptor potential channel 6 0.0074 0.0599 0.0622
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0038 0.0227 0.1662
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0512 0.4987
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0089 0.0231
Plasmodium vivax thioredoxin reductase, putative 0.01 0.0861 0.2395
Leishmania major cytochrome p450-like protein 0.0038 0.0227 0.2176
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0064 0.0066
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0119 0.0087
Loa Loa (eye worm) MH2 domain-containing protein 0.0257 0.2469 0.2811
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0047 0.0316 0.0325
Entamoeba histolytica hypothetical protein 0.0027 0.0119 0.0304
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0827 0.0937
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0038 0.0227 0.1662
Loa Loa (eye worm) hypothetical protein 0.0097 0.0827 0.0937
Schistosoma mansoni hypothetical protein 0.0097 0.0827 0.0895
Loa Loa (eye worm) thioredoxin reductase 0.01 0.0861 0.0975
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0252
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0038 0.0227 0.1662
Loa Loa (eye worm) inositol-1 0.0115 0.102 0.1157
Brugia malayi jmjC domain containing protein 0.0043 0.0283 0.0323
Schistosoma mansoni lipoxygenase 0.0247 0.2374 0.2582
Brugia malayi glutathione reductase 0.01 0.0861 0.0982
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0568 0.0589
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.113 0.118
Echinococcus granulosus inositol monophosphatase 1 0.0115 0.102 0.1065
Brugia malayi Calcitonin receptor-like protein seb-1 0.0305 0.2965 0.3382
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0305 0.2965 0.3382
Schistosoma mansoni BC026374 protein (S09 family) 0.0045 0.0304 0.0324
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0057 0.0421 0.0436
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1806 0.1891
Brugia malayi CXXC zinc finger family protein 0.0057 0.0417 0.0476
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.1114 0.1208
Echinococcus multilocularis cysteine protease 0.0019 0.0032 0.0026
Brugia malayi Inositol-1 0.0115 0.102 0.1164
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0057 0.0421 0.1162
Echinococcus multilocularis snurportin 1 0.0361 0.3537 0.371
Brugia malayi Carboxylesterase family protein 0.0045 0.0304 0.0346
Onchocerca volvulus 0.0045 0.0304 0.0273
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.1357 0.1419
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.113 0.1225
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0057 0.0421 0.5
Loa Loa (eye worm) hypothetical protein 0.0041 0.0262 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0038 0.0227 0.1662
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0057 0.0421 0.3123
Echinococcus granulosus transient receptor potential ion channel A 0.0109 0.095 0.0991
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0266 0.0283
Onchocerca volvulus 0.0041 0.0262 0.0231
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0576 0.5619
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.002
Schistosoma mansoni hypothetical protein 0.0361 0.3537 0.3851
Echinococcus granulosus peregrin 0.0091 0.0769 0.0801
Loa Loa (eye worm) hypothetical protein 0.0042 0.0266 0.0296
Echinococcus granulosus neuroligin 0.0045 0.0304 0.0312
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Echinococcus granulosus PHD finger protein rhinoceros 0.0087 0.0732 0.0762
Schistosoma mansoni inositol monophosphatase 0.0115 0.102 0.1106
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0576 0.5619
Plasmodium falciparum JmjC domain-containing protein, putative 0.0043 0.0283 0.0775
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2901 1
Trypanosoma brucei cytochrome P450, putative 0.0066 0.0512 0.4986
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0115 0.102 0.3446
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0305 0.2965 0.3377
Echinococcus granulosus muscleblind protein 0.0145 0.1326 0.1387
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0119 0.1107
Mycobacterium ulcerans carboxylesterase, LipT 0.0045 0.0304 0.0691
Echinococcus granulosus RUN 0.0041 0.0262 0.0268
Schistosoma mansoni importin beta-1 0.0034 0.0184 0.0194
Loa Loa (eye worm) CYP4Cod1 0.0066 0.0512 0.0577
Schistosoma mansoni polycystin 1-related 0.0041 0.0262 0.0278
Plasmodium falciparum thioredoxin reductase 0.01 0.0861 0.2395
Loa Loa (eye worm) hypothetical protein 0.0028 0.0123 0.0133
Echinococcus granulosus transient receptor potential gamma protein 0.0112 0.0988 0.1031
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.0512 0.4986
Echinococcus granulosus cytochrome P450 2K1 0.0038 0.0227 0.0232
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0316
Schistosoma mansoni hypothetical protein 0.01 0.0858 0.0929
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.01 0.0861 0.6438
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0038 0.0227 0.1662
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0038 0.0227 0.1662
Brugia malayi jmjC domain containing protein 0.0343 0.3353 0.3824
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0266 0.2558
Echinococcus multilocularis carboxylesterase 5A 0.0269 0.2595 0.2719
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0038 0.0227 0.1662
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Leishmania major GTP-binding protein, putative 0.0025 0.0093 0.0851
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0017 0.0011
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0089 0.0231
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0043 0.0283 0.2727
Brugia malayi hypothetical protein 0.0025 0.0089 0.0102
Echinococcus multilocularis neuropeptide s receptor 0.0945 0.9525 1
Brugia malayi Cytochrome P450 family protein 0.0066 0.0512 0.0584
Loa Loa (eye worm) hypothetical protein 0.0032 0.0163 0.0179
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0266 0.0235
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0262 0.0268
Loa Loa (eye worm) acetylcholinesterase 1 0.0269 0.2595 0.2954
Echinococcus multilocularis geminin 0.0911 0.9175 0.9633
Leishmania major trypanothione reductase 0.01 0.0861 0.843
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0093 0.0091
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0093 0.0106
Schistosoma mansoni acetylcholinesterase 0.0045 0.0304 0.0324
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0057 0.0421 0.409
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0012
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0285 0.0779
Echinococcus multilocularis acetylcholinesterase 0.0269 0.2595 0.2719
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0304 0.0324
Echinococcus multilocularis Smad4 0.0017 0.0017 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0568 0.3075
Schistosoma mansoni phosphatidylserine receptor 0.0043 0.0283 0.0302
Schistosoma mansoni transient receptor potential channel 4 0.0112 0.0988 0.1071
Echinococcus granulosus GPCR family 2 0.0097 0.0827 0.0862
Schistosoma mansoni survival motor neuron protein 0.01 0.0858 0.0929
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0266 0.2558
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0032 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0089 0.0231
Leishmania major cathepsin L-like protease 0.0019 0.0032 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0038 0.0227 0.1662
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0093 0.0851
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Brugia malayi Carboxylesterase family protein 0.0269 0.2595 0.2959
Echinococcus granulosus importin subunit beta 1 0.0034 0.0184 0.0187
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0064 0.0061
Brugia malayi jmjC domain containing protein 0.0043 0.0283 0.0323
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0184 0.0187
Toxoplasma gondii aminopeptidase n, putative 0.0365 0.3574 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0007 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Onchocerca volvulus Huntingtin homolog 0.0126 0.1126 0.1097
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0266 0.0283
Echinococcus granulosus jumonji domain containing protein 0.0121 0.1082 0.113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Brugia malayi isocitrate dehydrogenase 0.0016 0.0007 0.0008
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0103 0.0896 0.6703
Onchocerca volvulus 0.0045 0.0304 0.0273
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0017 0.0011
Schistosoma mansoni smad 0.0017 0.0017 0.0012
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0029 0.0023
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0057 0.0421 0.3123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Plasmodium vivax JmjC domain containing protein 0.0043 0.0283 0.0775
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0285 0.0292
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0262 0.0715
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.102 0.0992
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.102 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0047 0.0316 0.0325
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0057 0.0421 0.1162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Echinococcus multilocularis muscleblind protein 0.0145 0.1326 0.1387
Trichomonas vaginalis spcc417.12 protein, putative 0.0045 0.0304 0.0273
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0032 0.0026
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0057 0.0421 0.409
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0032 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0421 0.409
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0032 0.0247
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0269 0.2595 0.2954
Echinococcus multilocularis JmjC domain containing protein 4 0.0043 0.0283 0.029
Plasmodium falciparum thioredoxin reductase 0.0057 0.0421 0.1162
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0089 0.0231
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.2901 1
Plasmodium falciparum glutathione reductase 0.01 0.0861 0.2395
Loa Loa (eye worm) hypothetical protein 0.0087 0.0732 0.0828
Echinococcus granulosus neuropeptide s receptor 0.0945 0.9525 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0043 0.0283 0.0775
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0032 0.0026
Schistosoma mansoni cpg binding protein 0.0057 0.0417 0.0448
Brugia malayi Carboxylesterase family protein 0.0269 0.2595 0.2959
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0057 0.0421 0.3123
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.102 0.0992
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0032 0.0165 0.0445
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0012
Brugia malayi Carboxylesterase family protein 0.0045 0.0304 0.0346
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0057 0.0421 0.409
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0038 0.0227 0.1662
Toxoplasma gondii thioredoxin reductase 0.01 0.0861 0.2395
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0827 0.0862
Brugia malayi RNA, U transporter 1 0.0096 0.0823 0.0939
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0343 0.3353 0.3516
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0262 0.0268
Toxoplasma gondii aminopeptidase N, putative 0.0365 0.3574 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0087 0.0732 0.2032
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0029 0.0023
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0285 0.0254
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0126 0.113 0.1225
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0106 0.0921 0.0892
Echinococcus granulosus acetylcholinesterase 0.0269 0.2595 0.2719
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0032 0.0247
Echinococcus multilocularis short transient receptor potential channel 6 0.0074 0.0599 0.0622
Plasmodium vivax vivapain-2 0.0019 0.0032 0.007
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0285 0.0779
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0262 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0038 0.0227 0.1662
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0093 0.0091
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0064 0.0061
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0262 0.0715
Loa Loa (eye worm) hypothetical protein 0.0269 0.2595 0.2954
Schistosoma mansoni jumonji domain containing protein 0.0043 0.0283 0.0302
Brugia malayi Cathepsin L-like precursor 0.0019 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0145 0.1326 0.1506
Loa Loa (eye worm) hypothetical protein 0.0045 0.0304 0.0339
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0115 0.102 1
Onchocerca volvulus 0.0041 0.0262 0.0231
Leishmania major cytochrome p450-like protein 0.0066 0.0512 0.4986
Schistosoma mansoni Smad4 0.0017 0.0017 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0283 0.0316
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0045 0.0304 0.0312
Entamoeba histolytica heat shock transcription factor, putative 0.0106 0.0921 0.31
Loa Loa (eye worm) hypothetical protein 0.0106 0.0921 0.1044
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0032 0.0026
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0304 0.0324
Schistosoma mansoni hypothetical protein 0.0911 0.9175 1
Loa Loa (eye worm) acetyltransferase 0.0148 0.1357 0.1541
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0038 0.0227 0.2176
Loa Loa (eye worm) carboxylesterase 0.0045 0.0304 0.0339
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0093 0.0242
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0262 0.0268
Schistosoma mansoni hypothetical protein 0.0097 0.0827 0.0895
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0354 0.0404
Schistosoma mansoni transient receptor potential channel 0.0112 0.0988 0.1071
Echinococcus multilocularis phd:f box containing protein 0.0043 0.0283 0.029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Leishmania major cathepsin L-like protease 0.0072 0.0576 0.5619
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.1806 0.2054
Brugia malayi Muscleblind-like protein 0.0145 0.1326 0.1513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0568 0.3075
Mycobacterium tuberculosis Probable oxidoreductase 0.0057 0.0421 0.3123
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0057 0.0421 0.0452
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Plasmodium vivax SET domain protein, putative 0.0126 0.113 0.3147
Toxoplasma gondii NADPH-glutathione reductase 0.0057 0.0421 0.1162
Leishmania major cathepsin L-like protease 0.0019 0.0032 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0038 0.0227 0.1662
Brugia malayi cytochrome P450 0.0038 0.0227 0.0259
Loa Loa (eye worm) hypothetical protein 0.0041 0.0262 0.0291
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.102 1
Echinococcus multilocularis dnaJ subfamily B 0.0806 0.8092 0.8495
Echinococcus multilocularis BC026374 protein (S09 family) 0.0045 0.0304 0.0312
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2901 0.2878
Schistosoma mansoni hypothetical protein 0.0038 0.0227 0.0241
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Echinococcus granulosus smad 0.0017 0.0017 0.0011
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0043 0.0283 0.0775
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0045 0.0304 0.0312
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.013 0.0346
Toxoplasma gondii aminopeptidase N protein 0.0365 0.3574 1
Leishmania major cathepsin L-like protease 0.0072 0.0576 0.5619
Echinococcus multilocularis neuroligin 0.0045 0.0304 0.0312
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0057 0.0421 0.409
Entamoeba histolytica heat shock transcription factor, putative 0.0106 0.0921 0.31
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.0512 0.4986
Echinococcus granulosus short transient receptor potential channel 6 0.0074 0.0599 0.0622
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.102 1
Schistosoma mansoni hypothetical protein 0.0087 0.0732 0.0791
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0165 0.0445
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0827 0.0944
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0032 0.0027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0266 0.0272
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0568 0.0612
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0421 0.409
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0283 0.2727
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0038 0.0227 0.1662
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0576 0.5619
Loa Loa (eye worm) carboxylesterase 0.0269 0.2595 0.2954
Toxoplasma gondii cathepsin CPL 0.0019 0.0032 0.007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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