Detailed information for compound 1212028

Basic information

Technical information
  • TDR Targets ID: 1212028
  • Name: (5E,9E)-1-[bis(2,2-dimethylpropanoyloxymethox y)phosphoryl]-6,10,14-trimethylpentadeca-5,9, 13-triene-1-sulfonic acid
  • MW: 636.775 | Formula: C30H53O10PS
  • H donors: 1 H acceptors: 6 LogP: 7.69 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: C/C(=C\CCCC(P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)S(=O)(=O)O)/CC/C=C(/CCC=C(C)C)\C
  • InChi: 1S/C30H53O10PS/c1-23(2)15-13-17-25(4)19-14-18-24(3)16-11-12-20-26(42(34,35)36)41(33,39-21-37-27(31)29(5,6)7)40-22-38-28(32)30(8,9)10/h15-16,19,26H,11-14,17-18,20-22H2,1-10H3,(H,34,35,36)/b24-16+,25-19+
  • InChiKey: BIGLRRPOZQRLMH-DARFBZPXSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (5E,9E)-1-[bis(2,2-dimethylpropanoyloxymethoxy)phosphoryl]-6,10,14-trimethyl-pentadeca-5,9,13-triene-1-sulfonic acid
  • (5E,9E)-1-[bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphoryl]-6,10,14-trimethylpentadeca-5,9,13-triene-1-sulfonic acid
  • (5E,9E)-1-[bis(pivaloyloxymethoxy)phosphoryl]-6,10,14-trimethyl-pentadeca-5,9,13-triene-1-sulfonic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.065 0.3853
Echinococcus granulosus neuropeptide receptor A26 0.0017 0.0165 0.0192
Brugia malayi neuropeptide F receptor 0.0017 0.0165 0.032
Loa Loa (eye worm) beta-lactamase 0.0071 0.1385 0.2985
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0305 0.0232
Brugia malayi Fli-1 protein 0.0215 0.462 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.1385 0.1786
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Echinococcus multilocularis tar DNA binding protein 0.0128 0.2671 0.3466
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0401 0.2513
Schistosoma mansoni gabp alpha 0.0071 0.1378 0.1796
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.065 0.4663
Brugia malayi Muscleblind-like protein 0.0149 0.3135 0.6774
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0165 0.0192
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.065 0.4394
Echinococcus granulosus tar DNA binding protein 0.0128 0.2671 0.3466
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Echinococcus granulosus orexin receptor type 2 0.0017 0.0165 0.0192
Brugia malayi glutathione reductase 0.0037 0.0618 0.1305
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0165 0.0192
Echinococcus granulosus geminin 0.0351 0.7674 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0618 0.0548
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0017 0.0165 0.0338
Echinococcus granulosus g protein coupled receptor 0.0017 0.0165 0.0192
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Brugia malayi beta-lactamase family protein 0.0071 0.1385 0.2972
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0165 0.0192
Brugia malayi Thioredoxin reductase 0.0037 0.0618 0.1305
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0174 0.0664
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1243 0.162
Mycobacterium ulcerans beta-lactamase 0.0071 0.1385 0.8768
Trichomonas vaginalis esterase, putative 0.0071 0.1385 1
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.1569 0.2027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0000000003896
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0222 0.0463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1385 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0165 0.0214
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.1094 0.1426
Echinococcus granulosus g protein coupled receptor 0.0017 0.0165 0.0192
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.1385 0.132
Trypanosoma brucei trypanothione reductase 0.0037 0.0618 0.4147
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.1895 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Conserved protein 0.0071 0.1385 0.132
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0075 0.0475
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0618 0.4428
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.2485 0.5371
Schistosoma mansoni neuropeptide receptor 0.0017 0.0165 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus granulosus fmrfamide receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0165 0.0338
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0222 0.1552
Loa Loa (eye worm) hypothetical protein 0.0017 0.0174 0.0359
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0305 0.1541
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.1385 0.132
Schistosoma mansoni hypothetical protein 0.0351 0.7674 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0008 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0165 0.032
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.1006 0.2163
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Onchocerca volvulus 0.0017 0.0165 0.1015
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0536 0.1126
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0165 0.0338
Echinococcus multilocularis neuropeptide receptor A26 0.0017 0.0165 0.0192
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0165 0.0192
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0222 0.0987
Onchocerca volvulus 0.0017 0.0165 0.1015
Onchocerca volvulus 0.0071 0.1385 1
Onchocerca volvulus 0.0071 0.1385 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Brugia malayi Dopamine receptor 0.0017 0.0165 0.032
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.1895 0.1834
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0165 0.0192
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0165 0.0192
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.1385 0.132
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0305 0.0643
Leishmania major hypothetical protein, conserved 0.0071 0.1385 1
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0165 0.0192
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.2671 0.5773
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.1094 0.1406
Schistosoma mansoni hypothetical protein 0.0017 0.0165 0.0214
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0882 0.1895
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.1683 0.1621
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.065 0.4394
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0305 0.0625
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0165 0.032
Loa Loa (eye worm) fli-1 protein 0.0215 0.462 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0033 0.0536 0.1143
Treponema pallidum NADH oxidase 0.0013 0.0075 0.0424
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.1378 0.2971
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0075 0.048
Schistosoma mansoni biogenic amine receptor 0.0017 0.0165 0.0214
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0305 0.4688
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.065 1
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0008 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0071 0.1385 0.8827
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Mycobacterium tuberculosis Probable reductase 0.0084 0.1683 0.1621
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0305 0.1758
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0222 0.0445
Schistosoma mansoni tar DNA-binding protein 0.0128 0.2671 0.348
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0165 0.0192
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0133 0.0252
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Brugia malayi neuropeptide F receptor 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0165 0.0214
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0165 0.0338
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.1243 0.1601
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0222 0.0267
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0165 0.1015
Mycobacterium ulcerans lipase LipD 0.0071 0.1385 0.8768
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0222 0.1126
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0165 0.032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.1385 0.132
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.1569 0.2045
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.1683 0.1621
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0165 0.0214
Mycobacterium leprae conserved hypothetical protein 0.0071 0.1385 0.6792
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0305 0.0232
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.065 0.4394
Brugia malayi beta-lactamase family protein 0.0071 0.1385 0.2972
Echinococcus granulosus neuropeptide receptor 0.0017 0.0165 0.0192
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.1385 0.2972
Onchocerca volvulus 0.0017 0.0165 0.1015
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0165 0.032
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0222 0.1126
Schistosoma mansoni opsin-like receptor 0.0017 0.0165 0.0214
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.1569 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni amine GPCR 0.0017 0.0165 0.0214
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0165 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0165 0.0214
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0075 0.0475
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1385 0.1805
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0017 0.0019
Schistosoma mansoni hypothetical protein 0.0015 0.0133 0.0174
Schistosoma mansoni elf1 0.001 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0174 0.0359
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0165 0.0338
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.1385 0.8768
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Brugia malayi sulfakinin receptor protein 0.0017 0.0165 0.032
Echinococcus multilocularis somatostatin receptor 0.0017 0.0165 0.0192
Onchocerca volvulus 0.0017 0.0165 0.1015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0222 0.1126
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.065 0.4663
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1385 0.1805
Schistosoma mansoni hypothetical protein 0.0017 0.0165 0.0214
Brugia malayi Serotonin receptor 0.0017 0.0165 0.032
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.1385 0.132
Plasmodium vivax glutathione reductase, putative 0.0037 0.0618 0.3939
Schistosoma mansoni tar DNA-binding protein 0.0128 0.2671 0.348
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0165 0.032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1909 0.2488
Echinococcus granulosus hypothetical protein 0.0017 0.0165 0.0192
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0882 0.1879
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0165 0.0192
Brugia malayi GnHR receptor homolog 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0149 0.3135 0.678
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0075 0.0075
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.2671 0.5765
Loa Loa (eye worm) hypothetical protein 0.0023 0.0305 0.0643
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0305 0.1541
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.1569 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0075 0.0124
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Loa Loa (eye worm) hypothetical protein 0.0017 0.0174 0.0359
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Mycobacterium ulcerans hypothetical protein 0.0023 0.0305 0.1541
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0882 0.1879
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.1385 0.132
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0133 0.0151
Onchocerca volvulus 0.0017 0.0165 0.1015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0165 0.0214
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0165 0.0192
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.1378 0.1778
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.1378 0.1778
Loa Loa (eye worm) hypothetical protein 0.0015 0.0133 0.027
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0165 0.0192
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0165 0.0192
Schistosoma mansoni hypothetical protein 0.0017 0.0165 0.0214
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1909 0.2471
Onchocerca volvulus 0.0017 0.0165 0.1015
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0165 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0165 0.0338
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0165 0.0192
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0174 0.0664
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0222 0.0267
Loa Loa (eye worm) glutathione reductase 0.0037 0.0618 0.1322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1909 0.2471
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1385 1
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0165 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Schistosoma mansoni tar DNA-binding protein 0.0128 0.2671 0.348
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Schistosoma mansoni neuropeptide receptor 0.0017 0.0165 0.0214
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.1683 0.1621
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0165 0.0338
Mycobacterium ulcerans hypothetical protein 0.0071 0.1385 0.8768
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0305 0.1758
Schistosoma mansoni hypothetical protein 0.0351 0.7674 1
Brugia malayi AKH receptor 0.0017 0.0165 0.032
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0174 0.1108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0133 0.0151
Echinococcus granulosus neuropeptide receptor 0.0017 0.0165 0.0192
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0165 0.0214
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0075 0.0097
Brugia malayi RE15519p 0.0017 0.0165 0.032
Onchocerca volvulus 0.0017 0.0165 0.1015
Brugia malayi ORL1-like opioid receptor 0.0017 0.0165 0.032
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1385 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0305 0.1541
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1243 0.162
Schistosoma mansoni tar DNA-binding protein 0.0128 0.2671 0.348
Schistosoma mansoni hypothetical protein 0.0015 0.0133 0.0174
Onchocerca volvulus 0.0017 0.0165 0.1015
Echinococcus granulosus bloom syndrome protein 0.0019 0.0222 0.0267
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0165 0.032
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0133 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0133 0.0151
Schistosoma mansoni ets 0.001 0.0017 0.0023
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0165 0.0214
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0017 0.0023
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0401 0.0602
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0165 0.0192
Brugia malayi G protein-coupled receptor 0.0017 0.0165 0.032
Onchocerca volvulus 0.0017 0.0165 0.1015
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0305 0.4688
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0149 0.3135 0.678
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0075 0.0475
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0174 0.01
Schistosoma mansoni hypothetical protein 0.0017 0.0165 0.0214
Schistosoma mansoni ets-related 0.001 0.0017 0.0023
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0165 0.0214
Brugia malayi Ets-domain containing protein 0.0071 0.1378 0.2957
Brugia malayi Probable ClpP-like protease 0.0079 0.1569 0.3372
Leishmania major trypanothione reductase 0.0037 0.0618 0.4147
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.1243 0.7922
Echinococcus multilocularis GPCR, family 2 0.0015 0.0133 0.0151
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0165 0.0192
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1385 1
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0165 0.0192
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0153 0.0079
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0165 0.0192
Brugia malayi Melatonin receptor type 1A 0.0017 0.0165 0.032
Mycobacterium leprae Probable lipase LipE 0.0071 0.1385 0.6792
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1385 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0222 0.1126
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1243 0.7818
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Onchocerca volvulus 0.0023 0.0305 0.2048
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni inositol monophosphatase 0.0038 0.065 0.0847
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Echinococcus multilocularis serotonin receptor 0.0017 0.0165 0.0192
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.1385 0.8768
Onchocerca volvulus 0.0071 0.1385 1
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0955 0.0887
Loa Loa (eye worm) RecQ helicase 0.0019 0.0222 0.0463
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0305 0.0625
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0165 0.0338
Schistosoma mansoni amine GPCR 0.0017 0.0165 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0305 0.1541
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.2485 0.5371
Brugia malayi Serotonin receptor 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0222 0.0463
Brugia malayi putative neuropeptide receptor 0.0017 0.0165 0.032
Schistosoma mansoni neuropeptide receptor 0.0017 0.0165 0.0214
Brugia malayi Ets-domain containing protein 0.0071 0.1378 0.2957
Toxoplasma gondii thioredoxin reductase 0.0037 0.0618 0.3939
Loa Loa (eye worm) hypothetical protein 0.006 0.1148 0.247
Echinococcus granulosus somatostatin receptor 0.0017 0.0165 0.0192
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0165 0.0192
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.065 0.0827
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0629 0.0799
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0401 0.2553
Onchocerca volvulus 0.0017 0.0165 0.1015
Brugia malayi MH2 domain containing protein 0.012 0.2485 0.5362
Echinococcus multilocularis serotonin receptor 0.0017 0.0165 0.0192
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.1243 0.8917
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1243 0.7818
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Toxoplasma gondii ABC1 family protein 0.0071 0.1385 0.8827
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0165 0.0192
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0165 0.0192
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0165 0.0192
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1909 0.411
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.1243 0.1177
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1909 0.2488
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0222 0.0267
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.1385 0.132
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Onchocerca volvulus 0.0017 0.0165 0.1015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0165 0.0192
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0165 0.0192
Onchocerca volvulus 0.0017 0.0165 0.1015
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0629 0.0799
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0133 0.0252
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus granulosus allatostatin A receptor 0.0017 0.0165 0.0192
Schistosoma mansoni hypothetical protein 0.0033 0.0536 0.0698
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Loa Loa (eye worm) RNA binding protein 0.0128 0.2671 0.5773
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni hypothetical protein 0.001 0.0017 0.0023
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0165 0.0214
Echinococcus granulosus g protein coupled receptor 0.0017 0.0165 0.0192
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0165 0.0192
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.1094 0.1027
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0023 0.0305 0.0643
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0165 0.0192
Brugia malayi G-protein coupled receptor 0.0017 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Brugia malayi RNA binding protein 0.0128 0.2671 0.5765
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0305 0.0625
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0165 0.0192
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0075 0.0475
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.1094 0.1406
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0008 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0153 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0618 0.3939
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0165 0.0214
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.056 0.1603
Loa Loa (eye worm) hypothetical protein 0.0049 0.0882 0.1895
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0222 0.0445
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0165 0.0192
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0165 0.0192
Loa Loa (eye worm) TAR-binding protein 0.0128 0.2671 0.5773
Schistosoma mansoni neuropeptide receptor 0.0017 0.0165 0.0214
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0174 0.0664
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Echinococcus granulosus sex peptide receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0017 0.0019
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Echinococcus multilocularis muscleblind protein 1 0.0149 0.3135 0.4072
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0165 0.032
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0165 0.0192
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0165 0.0214
Schistosoma mansoni opsin-like receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0165 0.0192
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.065 0.4394
Schistosoma mansoni hypothetical protein 0.0015 0.0133 0.0174
Echinococcus granulosus GPCR family 2 0.0015 0.0133 0.0151
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0133 0.0151
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0165 0.0192
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.1569 0.2027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1909 0.2471
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis geminin 0.0351 0.7674 1
Schistosoma mansoni opsin-like receptor 0.0017 0.0165 0.0214
Schistosoma mansoni hypothetical protein 0.0015 0.0133 0.0174
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0174 0.0359
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0165 0.0192
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Echinococcus granulosus serotonin receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0071 0.1385 0.2985
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0165 0.0192
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.1895 0.1834
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.1895 0.1834
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0955 0.0887
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0165 0.0214
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0618 0.1322
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.065 0.4145
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni adenoreceptor 0.0017 0.0165 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0955 0.1225
Schistosoma mansoni histamine h1 receptor 0.0017 0.0165 0.0214
Plasmodium falciparum glutathione reductase 0.0037 0.0618 0.3636
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1909 0.4122
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0305 0.1541
Toxoplasma gondii hypothetical protein 0.0027 0.0401 0.2553
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0165 0.0338
Plasmodium falciparum thioredoxin reductase 0.0037 0.0618 0.3636
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0165 0.0192
Schistosoma mansoni myosin xvIII 0.0017 0.0165 0.0214
Loa Loa (eye worm) hypothetical protein 0.0079 0.1569 0.3384
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0222 0.0445
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0075 0.048
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0019
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.065 0.4394
Mycobacterium tuberculosis Conserved protein 0.0071 0.1385 0.132
Entamoeba histolytica recQ family DNA helicase 0.001 0.0008 0.013
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0165 0.0214
Brugia malayi Dopamine receptor protein 2 0.0017 0.0165 0.032
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0305 0.1541
Schistosoma mansoni tar DNA-binding protein 0.0128 0.2671 0.348
Onchocerca volvulus 0.0017 0.0165 0.1015
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Schistosoma mansoni biogenic amine receptor 0.0017 0.0165 0.0214
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0075 0.048
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0165 0.0192
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0165 0.0192
Schistosoma mansoni hypothetical protein 0.001 0.0017 0.0023
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0165 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1243 0.7818
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.1569 1
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0017 0.0019
Onchocerca volvulus 0.0017 0.0165 0.1015
Schistosoma mansoni DNA helicase recq1 0.0019 0.0222 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0305 0.1541
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1909 0.2488
Schistosoma mansoni inositol monophosphatase 0.0038 0.065 0.0847
Schistosoma mansoni ets-related 0.0215 0.462 0.602
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0165 0.0192
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.1094 0.6822
Brugia malayi Dopamine receptor protein 1 0.0017 0.0165 0.032
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.1094 0.234
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0165 0.0192
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0222 0.0987
Schistosoma mansoni amine GPCR 0.0017 0.0165 0.0214
Schistosoma mansoni biogenic amine receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0222 0.1126
Brugia malayi beta-lactamase 0.0071 0.1385 0.2972
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0222 0.1415
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.1243 0.1601
Brugia malayi G-protein coupled receptor 0.0017 0.0165 0.032
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1385 1
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0222 0.3415
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.1683 0.1621
Echinococcus multilocularis neuropeptide s receptor 0.0017 0.0165 0.0192
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Brugia malayi Inositol-1 0.0038 0.065 0.1375
Onchocerca volvulus 0.0017 0.0165 0.1015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0222 0.1415
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0165 0.032
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0955 0.1225
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0305 0.4688
Echinococcus granulosus neuropeptide s receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0019
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0401 0.2181
Schistosoma mansoni DNA helicase recq5 0.0019 0.0222 0.0289
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.1569 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0165 0.0214
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0165 0.1015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1909 0.2471
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Brugia malayi larval opioid receptor 0.0017 0.0165 0.032
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.1094 0.778
Echinococcus granulosus muscleblind protein 0.0149 0.3135 0.4072
Onchocerca volvulus 0.0017 0.0165 0.1015
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium tuberculosis Conserved protein 0.0071 0.1385 0.132
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0305 0.1758
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0165 0.0192
Echinococcus multilocularis sex peptide receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0165 0.0338
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.065 0.3853
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0222 0.0267
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0165 0.0192
Brugia malayi TAR-binding protein 0.0128 0.2671 0.5765
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0165 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0165 0.0192
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0955 0.4088
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.056 0.0489
Onchocerca volvulus 0.0017 0.0165 0.1015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0153 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Loa Loa (eye worm) hypothetical protein 0.0017 0.0174 0.0359
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0165 0.0192
Echinococcus multilocularis muscleblind protein 0.0149 0.3135 0.4072
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0075 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1385 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0165 0.0192
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.065 0.0827
Loa Loa (eye worm) inositol-1 0.0038 0.065 0.1392
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.1683 0.1621
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0165 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0222 0.0267
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1385 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.1385 0.1786
Schistosoma mansoni amine GPCR 0.0017 0.0165 0.0214
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0222 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.1683 0.8669
Schistosoma mansoni amine GPCR 0.0017 0.0165 0.0214
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.1569 0.795
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0075 0.048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0153 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Brugia malayi hypothetical protein 0.0017 0.0165 0.032
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0165 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0165 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.1094 0.6822
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.1385 0.2985
Loa Loa (eye worm) hypothetical protein 0.0017 0.0165 0.0338
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0165 0.0214

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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