Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.4585 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.5744 | 0.3468 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.2149 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5744 | 0.5406 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.4585 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.5744 | 0.5744 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0033 | 0.3485 | 0.2966 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.5744 | 0.3468 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.5744 | 0.3468 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.657 | 0.657 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5744 | 0.5406 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0.3781 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.4585 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.4585 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.4585 | 0.1689 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.004 | 0.4758 | 0.4599 |
Brugia malayi | Inositol-1 | 0.0039 | 0.4585 | 0.4421 |
Brugia malayi | hypothetical protein | 0.0026 | 0.2149 | 0.1911 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.4585 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.4585 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.4585 | 0.4154 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5744 | 0.5406 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0049 | 0.657 | 0.4736 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.5833 | 0.5501 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.2149 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 1 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.4585 | 0.4154 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.2149 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.5744 | 0.5616 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.4585 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.4585 | 0.1689 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0036 | 0.402 | 0.3839 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2149 | 0.2149 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.5744 | 0.3468 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.4585 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 1 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0049 | 0.657 | 0.4736 |
Loa Loa (eye worm) | glutamate receptor | 0.004 | 0.4758 | 0.4758 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.4585 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.3781 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.4585 | 0.5 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0019 | 0.0737 | 0.0457 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.4585 | 0.4585 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.4585 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.