Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | fibroinase | 0.0036 | 0.0119 | 0.0119 |
Echinococcus multilocularis | lamin dm0 | 0.0057 | 0.0403 | 0.0403 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.0119 | 0.0083 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0047 | 0.0047 |
Echinococcus granulosus | intermediate filament protein | 0.0057 | 0.0403 | 0.0423 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.0119 | 0.0036 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trichomonas vaginalis | set domain proteins, putative | 0.0258 | 0.3083 | 1 |
Echinococcus multilocularis | geminin | 0.0331 | 0.4069 | 0.4074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0207 | 0.0548 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0205 | 0.2373 | 0.5392 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.007 | 0.0129 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0313 | 0.3822 | 0.4474 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0833 | 0.0834 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.0654 | 0.1608 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Brugia malayi | hypothetical protein | 0.0277 | 0.3345 | 0.3345 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0153 | 0.1681 | 0.5 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0047 | 0.0047 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.006 | 0.044 | 0.108 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.007 | 0.0172 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0087 | 0.0794 | 0.0794 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.0369 | 0.0379 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0126 | 0.1322 | 0.1389 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1681 | 0.1681 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0057 | 0.0403 | 0.0403 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.1322 | 0.325 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.4069 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.044 | 0.044 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0093 | 0.088 | 0.0985 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0121 |
Plasmodium vivax | vivapain-2 | 0.0036 | 0.0119 | 0.0427 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.0119 | 0.0292 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0661 | 0.8481 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0661 | 0.8481 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0055 | 0.0369 | 0.0379 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.006 | 0.044 | 0.092 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.0119 | 0.0119 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.006 | 0.044 | 0.0463 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0369 | 0.1958 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1681 | 0.1681 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0369 | 0.0369 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0153 | 0.1681 | 0.3845 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.1476 | 0.1693 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.007 | 0.007 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0125 | 0.028 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0052 | 0.0328 | 0.0657 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0087 | 0.0794 | 0.0834 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.006 | 0.044 | 0.092 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0463 | 0.5831 | 0.5839 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.1293 | 0.3178 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0277 | 0.3345 | 0.8221 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0.2137 | 0.5253 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0145 | 0.157 | 0.3581 |
Echinococcus multilocularis | musashi | 0.0057 | 0.0403 | 0.0403 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0205 | 0.2373 | 0.6988 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.0037 | 0.0125 | 0.0042 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0205 | 0.2373 | 0.5392 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.006 | 0.044 | 0.1313 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.0119 | 0.0119 |
Onchocerca volvulus | 0.0258 | 0.3083 | 0.3024 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0057 | 0.0403 | 0.0403 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.0654 | 0.0655 |
Brugia malayi | Pre-SET motif family protein | 0.0226 | 0.2664 | 0.2664 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0076 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1681 | 0.1681 |
Echinococcus granulosus | neuropeptide s receptor | 0.0463 | 0.5831 | 0.6126 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.006 | 0.044 | 0.0754 |
Onchocerca volvulus | 0.006 | 0.044 | 0.0359 | |
Onchocerca volvulus | 0.0057 | 0.0403 | 0.0322 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0125 | 0.0179 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.006 | 0.044 | 0.1398 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Echinococcus multilocularis | tumor protein p63 | 0.0739 | 0.9518 | 0.953 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.2763 | 0.6393 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Brugia malayi | AMP-binding enzyme family protein | 0.0205 | 0.2373 | 0.2373 |
Brugia malayi | RNA binding protein | 0.0124 | 0.1293 | 0.1293 |
Brugia malayi | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.04 | 0.4981 | 0.4981 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0113 | 0.1152 | 0.1307 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0205 | 0.2373 | 0.5392 |
Brugia malayi | MH2 domain containing protein | 0.04 | 0.4981 | 0.4981 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0125 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0083 | 0.0083 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0125 | 0.0179 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0463 | 0.5831 | 0.6126 |
Schistosoma mansoni | hypothetical protein | 0.0277 | 0.3345 | 0.8221 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0774 | 0.9987 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.007 | 0.0074 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0463 | 0.5831 | 0.5839 |
Loa Loa (eye worm) | intermediate filament protein | 0.0057 | 0.0403 | 0.0403 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0145 | 0.157 | 0.3581 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0125 | 0.0179 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.0119 | 0.0292 |
Mycobacterium ulcerans | hypothetical protein | 0.0348 | 0.4295 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0348 | 0.4295 | 1 |
Onchocerca volvulus | 0.0045 | 0.0237 | 0.0155 | |
Brugia malayi | Heterochromatin protein 1 | 0.0076 | 0.0654 | 0.0654 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0145 | 0.157 | 0.3581 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0045 | 0.0237 | 0.0582 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0087 | 0.0794 | 0.0794 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.1476 | 0.1693 |
Onchocerca volvulus | 0.0037 | 0.0125 | 0.0042 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0138 | 0.1476 | 0.1693 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.1476 | 0.1693 |
Loa Loa (eye worm) | TAR-binding protein | 0.0124 | 0.1293 | 0.1293 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0125 | 0.0132 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0125 | 0.0125 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.006 | 0.044 | 0.1398 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0125 | 0.0125 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0794 | 0.1951 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.0463 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0125 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 0.3295 | 0.3295 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0661 | 0.8481 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0108 | 0.1082 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2373 | 0.2373 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.006 | 0.044 | 0.0754 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0833 | 0.2046 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0126 | 0.1317 | 0.1503 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.006 | 0.044 | 0.0463 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.007 | 0.0172 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0125 | 0.0179 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0833 | 0.0875 |
Plasmodium vivax | vivapain-2 | 0.0036 | 0.0119 | 0.0427 |
Schistosoma mansoni | lamin | 0.0057 | 0.0403 | 0.099 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.0833 | 0.0833 |
Brugia malayi | intermediate filament protein | 0.0057 | 0.0403 | 0.0403 |
Onchocerca volvulus | 0.006 | 0.044 | 0.0359 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0125 | 0.0467 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0205 | 0.2373 | 0.2757 |
Echinococcus granulosus | cathepsin l1 | 0.0036 | 0.0119 | 0.0125 |
Onchocerca volvulus | Cathepsin F homolog | 0.0036 | 0.0119 | 0.0036 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0274 | 0.3295 | 0.3295 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0124 | 0.1293 | 0.1293 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0369 | 0.1958 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0125 | 0.009 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0833 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0794 | 0.0794 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0125 | 0.0179 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0125 | 0.009 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0125 | 0.028 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.0119 | 0.0119 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3345 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0833 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1082 | 0.1082 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.0654 | 0.2019 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0036 | 0.0119 | 0.0427 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0125 | 0.028 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0036 | 0.0119 | 0.0427 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0205 | 0.2373 | 0.5392 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0145 | 0.157 | 0.3581 |
Loa Loa (eye worm) | cysteine protease | 0.0036 | 0.0119 | 0.0119 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0136 | 0.1458 | 0.146 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Loa Loa (eye worm) | oxidoreductase | 0.006 | 0.044 | 0.044 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.0119 | 0.0119 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.0463 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0108 | 0.1082 | 0.1225 |
Brugia malayi | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0205 | 0.2373 | 0.2757 |
Onchocerca volvulus | 0.006 | 0.044 | 0.0359 | |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.006 | 0.044 | 0.0994 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0153 | 0.1681 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.0119 | 0.0036 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0153 | 0.1681 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.007 | 0.0208 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0226 | 0.2664 | 0.2664 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0207 | 0.0207 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0207 | 0.0548 |
Echinococcus granulosus | geminin | 0.0331 | 0.4069 | 0.4275 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0036 | 0.0119 | 0.0125 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.1293 | 0.3178 |
Mycobacterium ulcerans | hypothetical protein | 0.0205 | 0.2373 | 0.5392 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0087 | 0.0794 | 0.0834 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.0833 | 0.0833 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.025 | 0.069 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0055 | 0.0369 | 0.1958 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.006 | 0.044 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.007 | 0.007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.1293 | 0.3178 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0125 | 0.0179 |
Echinococcus granulosus | tar DNA binding protein | 0.0124 | 0.1293 | 0.1359 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.006 | 0.044 | 0.0754 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.0119 | 0.0119 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.0654 | 0.0655 |
Leishmania major | cysteine peptidase A (CPA) | 0.0036 | 0.0119 | 0.0083 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0125 | 0.0125 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.2392 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.006 | 0.044 | 0.1398 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0036 | 0.0119 | 0.0119 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0036 | 0.0119 | 0.0427 |
Brugia malayi | chromobox protein homolog 3 | 0.0043 | 0.0207 | 0.0207 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.025 | 0.0168 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0006 | 0.0006 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.006 | 0.044 | 0.044 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0126 | 0.1322 | 0.1324 |
Onchocerca volvulus | 0.0108 | 0.1082 | 0.1007 | |
Leishmania major | mitochondrial DNA polymerase beta | 0.0661 | 0.8481 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0739 | 0.9518 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0036 | 0.0119 | 0.0083 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.044 | 0.092 |
Toxoplasma gondii | cathepsin CPL | 0.0036 | 0.0119 | 0.0688 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.0119 | 0.0083 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.006 | 0.044 | 0.092 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.0654 | 0.0687 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0125 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1681 | 0.1681 |
Schistosoma mansoni | lamin | 0.0057 | 0.0403 | 0.099 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0207 | 0.0124 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2373 | 0.2373 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0369 | 0.0369 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0153 | 0.1681 | 0.3732 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.4069 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0205 | 0.2373 | 0.5475 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.006 | 0.044 | 0.0754 |
Leishmania major | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.2137 | 0.2137 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.0119 | 0.0083 |
Brugia malayi | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Echinococcus granulosus | GPCR family 2 | 0.0087 | 0.0794 | 0.0834 |
Brugia malayi | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3345 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0794 | 0.1951 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0093 | 0.088 | 0.0985 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.0654 | 0.0687 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.006 | 0.044 | 0.0754 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0369 | 0.0379 |
Brugia malayi | AMP-binding enzyme family protein | 0.0205 | 0.2373 | 0.2373 |
Loa Loa (eye worm) | ctsf protein | 0.0036 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.044 | 0.044 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.006 | 0.044 | 0.092 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.007 | 0.0172 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0125 | 0.0179 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0369 | 0.0379 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0205 | 0.2373 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0125 | 0.0179 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0274 | 0.3295 | 0.3295 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.0654 | 0.2019 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0205 | 0.2373 | 0.6988 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Echinococcus granulosus | lamin dm0 | 0.0057 | 0.0403 | 0.0423 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0087 | 0.0794 | 0.0795 |
Toxoplasma gondii | propionate-CoA ligase | 0.006 | 0.044 | 0.3854 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0124 | 0.1293 | 0.1293 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.1293 | 0.3178 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Echinococcus multilocularis | GPCR, family 2 | 0.0087 | 0.0794 | 0.0795 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0006 | 0.0006 |
Brugia malayi | AMP-binding enzyme family protein | 0.0205 | 0.2373 | 0.2373 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0277 | 0.3345 | 0.3515 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0109 | 0.0109 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0205 | 0.2373 | 0.5392 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.044 | 0.092 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0187 | 0.2137 | 0.2137 |
Onchocerca volvulus | 0.0775 | 1 | 1 | |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.006 | 0.044 | 0.0463 |
Toxoplasma gondii | hypothetical protein | 0.0107 | 0.1062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1681 | 0.1681 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0087 | 0.0794 | 0.0795 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0274 | 0.3295 | 0.3295 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0205 | 0.2373 | 1 |
Echinococcus granulosus | lamin | 0.0057 | 0.0403 | 0.0423 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0093 | 0.088 | 0.0985 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.007 | 0.007 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.006 | 0.044 | 0.0754 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0087 | 0.0794 | 0.0794 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.1458 | 0.3583 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0052 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.044 | 0.092 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.1476 | 0.1693 |
Echinococcus multilocularis | lamin | 0.0057 | 0.0403 | 0.0403 |
Loa Loa (eye worm) | RNA binding protein | 0.0124 | 0.1293 | 0.1293 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.0463 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0125 | 0.0125 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.006 | 0.044 | 0.044 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.0654 | 0.1608 |
Echinococcus multilocularis | tar DNA binding protein | 0.0124 | 0.1293 | 0.1295 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0054 | 0.0057 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.0119 | 0.0083 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.1476 | 0.1693 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.1293 | 0.3178 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0277 | 0.3345 | 0.335 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0125 | 0.0752 |
Onchocerca volvulus | 0.006 | 0.044 | 0.0359 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.0119 | 0.0119 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0125 | 0.0125 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0125 | 0.009 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.006 | 0.044 | 0.0463 |
Onchocerca volvulus | 0.0057 | 0.0403 | 0.0322 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2373 | 0.2373 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0125 | 0.0308 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0036 | 0.0119 | 0.0125 |
Onchocerca volvulus | 0.0205 | 0.2373 | 0.2309 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0205 | 0.2373 | 0.5392 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0313 | 0.3822 | 0.4474 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.006 | 0.044 | 0.092 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.1476 | 0.1693 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.006 | 0.044 | 0.0754 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0119 | 0.0119 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.006 | 0.044 | 0.3854 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0125 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0403 | 0.0403 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.04 | 0.4981 | 0.4981 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.006 | 0.044 | 0.044 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0205 | 0.2373 | 0.5475 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.006 | 0.044 | 0.092 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0093 | 0.088 | 0.0985 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0833 | 0.2046 |
Brugia malayi | TAR-binding protein | 0.0124 | 0.1293 | 0.1293 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0055 | 0.0369 | 0.3154 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0205 | 0.2373 | 0.6988 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.006 | 0.044 | 0.1313 |
Schistosoma mansoni | intermediate filament proteins | 0.0057 | 0.0403 | 0.099 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0794 | 0.1951 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3345 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.006 | 0.044 | 0.0462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.006 | 0.044 | 0.092 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Onchocerca volvulus | 0.0037 | 0.0125 | 0.0042 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0313 | 0.3822 | 0.4474 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0125 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0119 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0794 | 0.1951 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.0119 | 0.0083 |
Leishmania major | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.0463 |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Onchocerca volvulus | 0.0036 | 0.0119 | 0.0036 | |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.006 | 0.044 | 0.3854 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0125 | 0.0179 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.044 | 0.092 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.006 | 0.044 | 0.044 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.1458 | 0.3583 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0205 | 0.2373 | 0.5392 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0119 | 0.0259 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.006 | 0.044 | 0.2392 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.0119 | 0.0119 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0833 | 0.2046 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3345 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0125 | 0.0308 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.025 | 0.069 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0049 | 0.0049 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0205 | 0.2373 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.1476 | 0.1693 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0125 | 0.0125 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.