Detailed information for compound 1217825

Basic information

Technical information
  • TDR Targets ID: 1217825
  • Name: 5-tert-butyl-N-[3-[(5-tert-butyl-3-methylfura n-2-carbonyl)amino]propyl]-3-methylfuran-2-ca rboxamide
  • MW: 402.527 | Formula: C23H34N2O4
  • H donors: 2 H acceptors: 2 LogP: 5.47 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1oc(cc1C)C(C)(C)C)NCCCNC(=O)c1oc(cc1C)C(C)(C)C
  • InChi: 1S/C23H34N2O4/c1-14-12-16(22(3,4)5)28-18(14)20(26)24-10-9-11-25-21(27)19-15(2)13-17(29-19)23(6,7)8/h12-13H,9-11H2,1-8H3,(H,24,26)(H,25,27)
  • InChiKey: GMZKIIBEMYADPC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-tert-butyl-N-[3-[(5-tert-butyl-3-methyl-furan-2-carbonyl)amino]propyl]-3-methyl-furan-2-carboxamide
  • 5-tert-butyl-N-[3-[[(5-tert-butyl-3-methyl-2-furyl)-oxomethyl]amino]propyl]-3-methyl-2-furancarboxamide
  • 5-tert-butyl-N-[3-[(5-tert-butyl-3-methyl-furan-2-carbonyl)amino]propyl]-3-methyl-2-furamide
  • 5-tert-butyl-N-[3-[(5-tert-butyl-3-methyl-furan-2-yl)carbonylamino]propyl]-3-methyl-furan-2-carboxamide
  • ZINC04571115
  • MLS000527820
  • BAS 06316714
  • SMR000120394

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni chromobox protein 0.0025 0.0022 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0176 0.1057 0.1429
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0382 0.0516
Loa Loa (eye worm) jmjC domain-containing protein 0.0258 0.1618 0.1618
Giardia lamblia Histone acetyltransferase GCN5 0.013 0.0741 0.1465
Echinococcus multilocularis phd:f box containing protein 0.0066 0.0302 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0011 0.0011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0382 0.0382
Echinococcus granulosus fetal alzheimer antigen falz 0.0102 0.055 0.0745
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.005 0.0192 0.0192
Brugia malayi SET domain containing protein 0.003 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Echinococcus granulosus Chromo domain 0.0025 0.0022 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0062
Mycobacterium ulcerans glutaminase 0.0612 0.4041 0.8005
Trypanosoma cruzi ISWI complex protein 0.0068 0.0316 0.0348
Trichomonas vaginalis esterase, putative 0.0078 0.0382 0.044
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0029 0.0033
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0011 0.0017
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0001 0.0001
Echinococcus granulosus 6 phosphofructokinase 0.0241 0.1502 0.2033
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0065 0.0296 0.0581
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0194 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0032 0.0071 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0106 0.0573 0.0573
Brugia malayi hypothetical protein 0.003 0.0053 0.0053
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0361 0.0714
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0106 0.0573 0.1135
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0022 0.004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0382 0.058
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Brugia malayi phosphofructokinase 0.0241 0.1502 0.1502
Trypanosoma brucei DNA damage repair protein, putative 0.008 0.0397 0.0438
Loa Loa (eye worm) hypothetical protein 0.0106 0.0573 0.0573
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0199 0.022
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0199 0.022
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni lozenge 0.0186 0.1122 0.1705
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0759 0.5048 1
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0488 0.0562
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Toxoplasma gondii bromodomain-containing protein 0.0022 0.0002 0.0005
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0382 0.0516
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0199 0.022
Brugia malayi PHD-finger family protein 0.0098 0.0517 0.0517
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0029 0.005 0.01
Brugia malayi TAZ zinc finger family protein 0.0022 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0011 0.0011
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0022 0.0002 0.0004
Onchocerca volvulus 0.0078 0.0382 0.038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0106 0.0573 0.1135
Echinococcus multilocularis polybromo 1 0.0022 0.0002 0.0003
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1347 0.9075 1
Trypanosoma cruzi Bromodomain, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis cpg binding protein 0.0043 0.0144 0.0195
Brugia malayi glutaminase DH11.1 0.0612 0.4041 0.4041
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0039 0.0115 0.0126
Onchocerca volvulus 0.0031 0.0062 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0382 0.0756
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0011 0.0017
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0199 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Trypanosoma brucei small ubiquitin-related modifier 0.0127 0.0717 0.079
Trypanosoma brucei DNA polymerase IV, putative 0.0377 0.2429 0.2676
Echinococcus granulosus jumonji domain containing protein 0.0136 0.0779 0.1053
Chlamydia trachomatis phosphoglycerate kinase 0.0759 0.5048 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0294 0.1865 0.2056
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Echinococcus granulosus polycomb protein SCMH1 0.016 0.0942 0.1274
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0011 0.0015
Brugia malayi 6-phosphofructokinase 0.0241 0.1502 0.1502
Entamoeba histolytica deoxycytidyl transferase, putative 0.0258 0.1616 0.1862
Trichomonas vaginalis phosphofructokinase, putative 0.0241 0.1502 0.1731
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0012 0.0012
Brugia malayi Inositol-1 0.0041 0.0129 0.0129
Trypanosoma cruzi Bromodomain, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0022 0.004
Leishmania major hypothetical protein, conserved 0.005 0.0192 0.0211
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0022 0.0026
Schistosoma mansoni phosphoglycerate kinase 0.0759 0.5048 0.7671
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0063 0.0277 0.0306
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0003 0.0004
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0053
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.1286 0.1417
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0031 0.0062 0.0117
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Schistosoma mansoni chromobox protein 0.0155 0.0909 0.1381
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0002 0.0005
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0031 0.0062 0.0122
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0011 0.0015
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.0004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni DNA helicase recq5 0.0161 0.0949 0.1442
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0153 0.0895 0.1773
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Echinococcus multilocularis dna polymerase eta 0.0372 0.2395 0.3239
Echinococcus granulosus segment polarity protein dishevelled 0.003 0.0053 0.0071
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.003 0.0053 0.008
Brugia malayi CXXC zinc finger family protein 0.0033 0.0073 0.0073
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0011 0.0015
Trichomonas vaginalis DNA helicase recq, putative 0.0263 0.1652 0.1903
Mycobacterium ulcerans 6-phosphofructokinase 0.0241 0.1502 0.2976
Plasmodium vivax acyl-CoA synthetase, putative 0.0079 0.039 0.0773
Echinococcus multilocularis jumonji domain containing 1A 0.0066 0.0302 0.0408
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0011 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0536 0.0725
Entamoeba histolytica recQ family DNA helicase 0.0082 0.041 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Echinococcus granulosus expressed protein 0.0074 0.0357 0.0483
Brugia malayi beta-lactamase family protein 0.0078 0.0382 0.0382
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0129 0.0148
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.021 0.1286 0.1286
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0031 0.0062 0.0122
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0062 0.0068
Echinococcus granulosus bromodomain containing 2 0.0022 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0287 0.1818 0.2003
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0397 0.0438
Brugia malayi ImpB/MucB/SamB family protein 0.0372 0.2395 0.2395
Schistosoma mansoni ap endonuclease 0.0063 0.0277 0.0422
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0199 0.027
Leishmania major 4-coumarate:coa ligase-like protein 0.0106 0.0573 0.0632
Schistosoma mansoni zinc finger protein 0.0068 0.0316 0.0481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Brugia malayi Bromodomain containing protein 0.0183 0.11 0.11
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0011 0.0011
Entamoeba histolytica phosphofructokinase, putative 0.0241 0.1502 0.1731
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi nuclear hormone receptor 0.0024 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0242 0.1507 0.2982
Schistosoma mansoni blooms syndrome DNA helicase 0.0082 0.041 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trypanosoma cruzi Bromodomain, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0023 0.0003 0.0004
Echinococcus multilocularis PH interacting protein 0.0022 0.0002 0.0003
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0182 0.1094 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0022 0.0026
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Echinococcus multilocularis Chromo domain 0.0025 0.0022 0.003
Schistosoma mansoni z-protein (S1r protein) 0.0051 0.02 0.0304
Onchocerca volvulus 0.0161 0.0953 0.0951
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.044
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0076 0.0373 0.0504
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0001 0.0002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0194 0.1176 0.2329
Echinococcus multilocularis protein kinase C binding protein 1 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0133 0.0757 0.0757
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0031 0.0062 0.0122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0145 0.084 0.084
Onchocerca volvulus 0.0025 0.0022 0.002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0011 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0011 0.0015
Toxoplasma gondii PHD-finger domain-containing protein 0.0098 0.0517 0.1024
Giardia lamblia DINP protein human, muc B family 0.0287 0.1818 0.3598
Trypanosoma cruzi DNA polymerase eta, putative 0.0372 0.2395 0.2639
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.039
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0066 0.0302 0.0332
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0066 0.0302 0.0302
Schistosoma mansoni sex comb on midleg homolog 0.016 0.0942 0.1432
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma brucei chrX additional, unordered contigs 0.008 0.0397 0.0438
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0199 0.023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0003 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0022 0.0002 0.0003
Schistosoma mansoni chromobox protein 0.0025 0.0022 0.0034
Schistosoma mansoni kinase 0.0107 0.0579 0.088
Mycobacterium ulcerans hypothetical protein 0.008 0.0397 0.0787
Schistosoma mansoni phosphatidylserine receptor 0.0066 0.0302 0.0458
Schistosoma mansoni importin beta-1 0.0032 0.0071 0.0108
Brugia malayi DIX domain containing protein 0.003 0.0053 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.0004
Echinococcus multilocularis 0.0022 0.0002 0.0003
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0604 0.3986 0.3985
Loa Loa (eye worm) hypothetical protein 0.0202 0.1232 0.1232
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma brucei AAA ATPase, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0025 0.0022 0.0034
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0062 0.0068
Trichomonas vaginalis phosphofructokinase, putative 0.0241 0.1502 0.1731
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0382 0.0421
Echinococcus granulosus serine:threonine protein kinase PLK1 0.021 0.1286 0.174
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0536 0.1061
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0022 0.0044
Loa Loa (eye worm) hypothetical protein 0.016 0.0942 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0067
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Echinococcus granulosus tar DNA binding protein 0.0194 0.1176 0.1591
Schistosoma mansoni hypothetical protein 0.0374 0.2411 0.3664
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0011 0.0011
Trypanosoma brucei phosphoglycerate kinase 0.0279 0.1757 0.1937
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0022 0.004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0011 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Mycobacterium ulcerans acetyl-CoA synthetase 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0011 0.0011
Echinococcus multilocularis PHD finger protein rhinoceros 0.0098 0.0517 0.0699
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0022 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0025 0.0022 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0011 0.0017
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni dishevelled 0.003 0.0053 0.008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0695 0.4608 0.4608
Trypanosoma brucei DNA polymerase kappa, putative 0.0199 0.121 0.1333
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0032 0.0067 0.0074
Echinococcus granulosus expressed protein 0.042 0.2725 0.3686
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0031 0.0062 0.0068
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0011 0.0011
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0641 0.4243 0.574
Plasmodium vivax acetyl-CoA synthetase, putative 0.0031 0.0062 0.0122
Loa Loa (eye worm) hypothetical protein 0.0171 0.1021 0.1021
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0012 0.0014
Echinococcus granulosus chromobox protein 1 0.0155 0.0909 0.1229
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0079 0.039 0.0773
Loa Loa (eye worm) MH2 domain-containing protein 0.0259 0.1623 0.1623
Echinococcus granulosus PH interacting protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Onchocerca volvulus 0.006 0.026 0.0258
Entamoeba histolytica dual specificity protein phosphatase, putative 0.1289 0.8682 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0361 0.0714
Echinococcus granulosus chromobox protein 2 0.0025 0.0022 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis polycomb protein SCMH1 0.016 0.0942 0.1274
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0011 0.0015
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0241 0.1502 0.2568
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0517 0.1024
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0106 0.0573 0.1135
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0031 0.0062 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0207 0.1269 0.1399
Echinococcus granulosus SAM and MBT domain containing protein 0.016 0.0942 0.1274
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0024 0.0014 0.0016
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0345 0.0397
Leishmania major mitochondrial DNA polymerase beta 0.1347 0.9075 1
Mycobacterium ulcerans hypothetical protein 0.0709 0.4709 0.9328
Toxoplasma gondii exonuclease III APE 0.0063 0.0277 0.055
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0011 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0302 0.0302
Brugia malayi beta-lactamase family protein 0.0078 0.0382 0.0382
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0128 0.0141
Loa Loa (eye worm) BRM protein 0.0022 0.0002 0.0002
Echinococcus multilocularis histone acetyltransferase MYST2 0.0182 0.1093 0.1479
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0065 0.0296 0.0341
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0011 0.0011
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0161 0.0949 0.1876
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0361 0.0714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0199 0.023
Brugia malayi jmjC domain containing protein 0.0066 0.0302 0.0302
Trichomonas vaginalis ubiquitin, putative 0.006 0.026 0.03
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0126 0.0709 0.1078
Brugia malayi BRM protein 0.0022 0.0002 0.0002
Brugia malayi N-terminal motif family protein 0.0604 0.3986 0.3986
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus granulosus Small ubiquitin modifier 2 0.0127 0.0717 0.097
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0072 0.0345 0.038
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0759 0.5048 1
Toxoplasma gondii hypothetical protein 0.0217 0.1337 0.2648
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0093 0.0488 0.0486
Trichomonas vaginalis antibiotic synthetase, putative 0.0031 0.0062 0.0071
Onchocerca volvulus Serine\/threonine kinase homolog 0.021 0.1286 0.1284
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0361 0.0714
Schistosoma mansoni dishevelled 0.003 0.0053 0.008
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0022 0.0002 0.0003
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0199 0.023
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0059 0.0251 0.0276
Trichomonas vaginalis DNA helicase recq1, putative 0.0263 0.1652 0.1903
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0011 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Plasmodium falciparum histone acetyltransferase GCN5 0.013 0.0741 0.1465
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0071 0.0078
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0084 0.0097
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0062 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0147
Echinococcus multilocularis global transcription activator snf2l2 0.0022 0.0002 0.0003
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0011 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0002 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.1057 0.1606
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0099 0.0528 0.0528
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0296 0.0586
Echinococcus multilocularis Bromodomain containing protein 0.0022 0.0002 0.0003
Brugia malayi RNA recognition motif domain containing protein 0.0194 0.1176 0.1176
Brugia malayi hypothetical protein 0.0035 0.0088 0.0088
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0093 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi TAR-binding protein 0.0194 0.1176 0.1176
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0161 0.0949 0.0949
Echinococcus granulosus ubiquitin 0.006 0.026 0.0352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0194 0.1176 0.1787
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0031 0.0062 0.0062
Plasmodium falciparum bromodomain protein 1 0.0022 0.0002 0.000000056607
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0101
Plasmodium vivax JmjC domain containing protein 0.0066 0.0302 0.0598
Plasmodium vivax SET domain containing protein 0.0027 0.0032 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0011 0.0011
Schistosoma mansoni ran 0.0024 0.0012 0.0019
Brugia malayi polybromodomain protein 0.0022 0.0002 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0287 0.1818 0.2003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0088 0.0452 0.0895
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0011 0.0011
Brugia malayi hypothetical protein 0.0032 0.007 0.007
Echinococcus granulosus segment polarity protein dishevelled 0.003 0.0053 0.0071
Trichomonas vaginalis flap endonuclease-1, putative 0.0059 0.0251 0.0289
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0759 0.5048 1
Entamoeba histolytica hypothetical protein 0.0025 0.0022 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Trichomonas vaginalis DNA helicase recq, putative 0.0182 0.1094 0.1261
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0641 0.4243 0.574
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0073 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0207 0.1269 0.1399
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0066 0.0302 0.0458
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0029 0.0032
Loa Loa (eye worm) transcription factor SMAD2 0.0259 0.1623 0.1623
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0022 0.0026
Echinococcus multilocularis jumonji domain containing protein 0.0136 0.0779 0.1053
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0449 0.2926 0.3959
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0011 0.0011
Toxoplasma gondii bromodomain-containing protein 0.0022 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0092 0.0479 0.0728
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1347 0.9075 1
Schistosoma mansoni cpg binding protein 0.0033 0.0073 0.0111
Echinococcus granulosus CREB binding protein 0.0022 0.0002 0.0003
Echinococcus granulosus lysine specific demethylase 5A 0.0258 0.1618 0.2189
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0022 0.0002 0.0004
Echinococcus granulosus bloom syndrome protein 0.0263 0.1652 0.2235
Loa Loa (eye worm) hypothetical protein 0.006 0.0261 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Echinococcus multilocularis dna polymerase kappa 0.0377 0.2429 0.3286
Echinococcus granulosus Bromodomain containing protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.0756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0536 0.0814
Loa Loa (eye worm) hypothetical protein 0.0087 0.0443 0.0443
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0062 0.0068
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0022 0.0026
Leishmania major GTP-binding protein, putative 0.0024 0.0012 0.0014
Onchocerca volvulus 0.0031 0.0062 0.0059
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0074 0.0357 0.0357
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0011 0.0015
Onchocerca volvulus 0.0031 0.0062 0.0059
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0011 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0499 0.3267 0.442
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0022 0.0022
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0382 0.044
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0039 0.0115 0.0227
Loa Loa (eye worm) jmjC domain-containing protein 0.0201 0.1229 0.1229
Brugia malayi hypothetical protein 0.0099 0.0528 0.0528
Mycobacterium leprae Probable lipase LipE 0.0078 0.0382 0.0756
Brugia malayi mbt repeat family protein 0.016 0.0942 0.0942
Trichomonas vaginalis DNA polymerase eta, putative 0.0377 0.2429 0.2798
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.021 0.1286 0.1417
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0106 0.0573 0.0573
Toxoplasma gondii bromodomain-containing protein 0.0022 0.0002 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0199 0.0199
Echinococcus granulosus polybromo 1 0.0022 0.0002 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0029 0.0033
Trypanosoma cruzi bromodomain factor 2 protein 0.0022 0.0002 0.0003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0098 0.0517 0.0786
Echinococcus multilocularis zinc finger protein 0.0101 0.0541 0.0732
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0294 0.1865 0.2056
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0443 0.051
Onchocerca volvulus 0.0024 0.0011 0.0009
Echinococcus granulosus protein kinase C binding protein 1 0.0022 0.0002 0.0003
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0031 0.0062 0.0122
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0072 0.0345 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0031 0.0062 0.0122
Echinococcus granulosus histone lysine methyltransferase setb 0.0176 0.1057 0.1429
Trypanosoma brucei DNA polymerase IV, putative 0.0377 0.2429 0.2676
Leishmania major importin beta-1 subunit, putative 0.0026 0.0029 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0031 0.0062 0.0083
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0546 0.0546
Schistosoma mansoni methyl-cpg binding protein mbd 0.0076 0.037 0.0562
Schistosoma mansoni ran 0.0024 0.0012 0.0019
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0145 0.084 0.1277
Onchocerca volvulus 0.1482 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0382 0.0756
Schistosoma mansoni hypothetical protein 0.0035 0.0088 0.0134
Echinococcus granulosus Chromobox protein 3 0.0025 0.0022 0.003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0377 0.2429 0.2798
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Schistosoma mansoni survival motor neuron protein 0.0102 0.0546 0.083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0199 0.023
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0382 0.0756
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0759 0.5048 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0101
Brugia malayi PHD-finger family protein 0.0042 0.0138 0.0138
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0093 0.0093
Brugia malayi hypothetical protein 0.006 0.026 0.026
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0011 0.0011
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0129 0.0148
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0011 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.006 0.026 0.03
Treponema pallidum ATP-dependent DNA helicase 0.0082 0.041 0.0277
Treponema pallidum phosphoglycerate kinase 0.0759 0.5048 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Entamoeba histolytica recQ family helicase, putative 0.0079 0.0388 0.0447
Brugia malayi Importin beta-1 subunit 0.0032 0.0071 0.0071
Loa Loa (eye worm) PHD-finger family protein 0.0092 0.0479 0.0479
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0093 0.0126
Loa Loa (eye worm) TAR-binding protein 0.0194 0.1176 0.1176
Brugia malayi AF-10 protein 0.0032 0.0067 0.0067
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0063 0.0277 0.055
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0189 0.1146 0.1263
Loa Loa (eye worm) hypothetical protein 0.0161 0.0949 0.0949
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi translation initiation factor 4E 0.0039 0.0115 0.0115
Entamoeba histolytica phosphofructokinase, putative 0.0241 0.1502 0.1731
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0145 0.084 0.084
Echinococcus granulosus snurportin 1 0.0346 0.2221 0.3004
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0182 0.1093 0.1479
Mycobacterium ulcerans acyl-CoA synthetase 0.0106 0.0573 0.1135
Brugia malayi polk-prov protein 0.0199 0.121 0.121
Schistosoma mansoni dep domain containing protein 0.003 0.0053 0.008
Schistosoma mansoni blooms syndrome DNA helicase 0.0181 0.1092 0.1659
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0022 0.0002 0.0005
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0241 0.1502 0.1656
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0039 0.0115 0.0126
Trypanosoma brucei unspecified product 0.0347 0.2227 0.2454
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0372 0.2395 0.2395
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0106 0.0573 0.1135
Schistosoma mansoni phd finger protein 0.0022 0.0002 0.0004
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Leishmania major eukaryotic translation initiation factor-like 0.0039 0.0115 0.0126
Onchocerca volvulus 0.0068 0.0315 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.056 0.0645
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0032 0.0067 0.0133
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0031 0.0062 0.0122
Echinococcus multilocularis JmjC domain containing protein 4 0.0066 0.0302 0.0408
Schistosoma mansoni cpg binding protein 0.0043 0.0144 0.0219
Onchocerca volvulus 0.0078 0.0382 0.038
Brugia malayi regulator of G-protein signaling egl-10 0.0051 0.02 0.02
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0022 0.0002 0.0003
Brugia malayi Pre-SET motif family protein 0.01 0.0536 0.0536
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0102
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0076 0.0088
Trypanosoma cruzi Bromodomain, putative 0.0022 0.0002 0.0003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0759 0.5048 0.5563
Echinococcus granulosus regulator of G protein signaling 7 0.0051 0.02 0.0271
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0002 0.0002
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0011 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0506 0.0684
Schistosoma mansoni hypothetical protein 0.0102 0.0546 0.083
Echinococcus granulosus methyl CpG binding domain protein 2 0.0076 0.037 0.05
Toxoplasma gondii bromodomain-containing protein 0.0022 0.0002 0.0005
Echinococcus multilocularis peregrin 0.012 0.067 0.0907
Trypanosoma cruzi DNA damage repair protein, putative 0.008 0.0397 0.0438
Trypanosoma cruzi DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Giardia lamblia Kinase, PLK 0.021 0.1286 0.2544
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0079 0.039 0.0773
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.005 0.0057
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0012 0.0017
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0059 0.0251 0.0276
Schistosoma mansoni transcription initiation factor tfiid 0.0022 0.0002 0.0004
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0062 0.0122
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0637 0.4215 0.4645
Brugia malayi AMP-binding enzyme family protein 0.0106 0.0573 0.0573
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0494 0.3232 0.4911
Brugia malayi Ubiquitin-like protein SMT3 0.0127 0.0717 0.0717
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0059 0.0251 0.0276
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma brucei phosphoglycerate kinase 0.0759 0.5048 0.5563
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0031 0.0062 0.0068
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0294 0.1865 0.2056
Schistosoma mansoni regulator of G protein signaling 0.0051 0.02 0.0304
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Brugia malayi hypothetical protein 0.005 0.0192 0.0192
Trypanosoma brucei DNA polymerase IV, putative 0.0347 0.2227 0.2454
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0081 0.016
Entamoeba histolytica hypothetical protein 0.0025 0.0022 0.0026
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0382 0.0756
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium falciparum flap endonuclease 1 0.0059 0.0251 0.0492
Loa Loa (eye worm) glutaminase 2 0.0612 0.4041 0.4041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Loa Loa (eye worm) helicase 0.0025 0.0022 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0106 0.0573 0.0573
Schistosoma mansoni CREB-binding protein 2 0.0022 0.0002 0.0004
Loa Loa (eye worm) acetyltransferase 0.0494 0.3232 0.3232
Echinococcus granulosus peregrin 0.012 0.067 0.0907
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0022 0.0026
Schistosoma mansoni polybromo-1 0.0022 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0012 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0397 0.0438
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0129 0.0148
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0022 0.0002 0.0005
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0031 0.0062 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0056 0.0065
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0129 0.0142
Brugia malayi chromobox protein homolog 3 0.0087 0.0443 0.0443
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0012 0.002
Leishmania major small ubiquitin protein, putative 0.0127 0.0717 0.079
Trichomonas vaginalis hypothetical protein 0.0022 0.0002 0.0003
Schistosoma mansoni rotamase 0.0074 0.0357 0.0543
Schistosoma mansoni hypothetical protein 0.0983 0.6581 1
Entamoeba histolytica hypothetical protein 0.006 0.026 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0759 0.5048 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi jmjC domain containing protein 0.0066 0.0302 0.0302
Echinococcus granulosus histone acetyltransferase KAT2B 0.047 0.3067 0.4149
Trypanosoma cruzi bromodomain-containing protein 3 0.0022 0.0002 0.0003
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.003 0.0053 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0063 0.0277 0.0306
Loa Loa (eye worm) hypothetical protein 0.0193 0.1174 0.1174
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0012 0.0012
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0296 0.0586
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0199 0.0303
Trichomonas vaginalis bromodomain-containing protein, putative 0.0153 0.0895 0.1031
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0012 0.0025
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0192 0.0211
Loa Loa (eye worm) inositol-1 0.0041 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.005 0.0057
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0182 0.1094 0.1206
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0382 0.0756
Plasmodium falciparum JmjC domain-containing protein, putative 0.0066 0.0302 0.0593
Giardia lamblia Sentrin 0.0127 0.0717 0.1417
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0031 0.0062 0.0122
Schistosoma mansoni 6-phosphofructokinase 0.0241 0.1502 0.2283
Brugia malayi hypothetical protein 0.003 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0066 0.0302 0.0302
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Toxoplasma gondii ABC1 family protein 0.0078 0.0382 0.0756
Trypanosoma brucei Bromodomain, putative 0.0022 0.0002 0.0003
Echinococcus granulosus CREB binding protein 0.0022 0.0002 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0155 0.0909 0.1047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0034 0.0081 0.0156
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0106 0.0573 0.1135
Echinococcus granulosus cpg binding protein 0.0043 0.0144 0.0195
Loa Loa (eye worm) hypothetical protein 0.0759 0.5048 0.5048
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Onchocerca volvulus 0.0126 0.0709 0.0707
Trypanosoma cruzi small ubiquitin protein, putative 0.0127 0.0717 0.079
Echinococcus multilocularis SAM and MBT domain containing protein 0.016 0.0942 0.1274
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0011 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0192 0.0379
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0127 0.0717 0.109
Giardia lamblia DNA damage repair protein 0.008 0.0397 0.0783
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0346 0.2221 0.3375
Brugia malayi polybromodomain protein 0.0022 0.0002 0.0002
Brugia malayi Bloom's syndrome protein homolog 0.0263 0.1652 0.1652
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0231 0.143 0.1576
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0382 0.0382
Echinococcus granulosus survival motor neuron protein 1 0.0499 0.3267 0.442
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0056 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0397 0.0438
Brugia malayi CHD4 protein 0.0036 0.0093 0.0093
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0106 0.0573 0.1135
Echinococcus multilocularis tar DNA binding protein 0.0194 0.1176 0.1591
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0199 0.027
Plasmodium vivax small ubiquitin-related modifier, putative 0.0127 0.0717 0.1421
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0382 0.0756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0148 0.0171
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0302 0.0458
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0031 0.0062 0.0083
Loa Loa (eye worm) SMO-1 protein 0.0127 0.0717 0.0717
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0129 0.0148
Trichomonas vaginalis glutaminase, putative 0.0612 0.4041 0.4655
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0022 0.0002 0.0003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0129 0.0255
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0189 0.1146 0.1263
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.1289 0.8682 1
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0192 0.0375
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0011 0.0009
Trypanosoma brucei Bromodomain, putative 0.0022 0.0002 0.0003
Toxoplasma gondii PHD-finger domain-containing protein 0.0098 0.0517 0.1024
Brugia malayi hypothetical protein 0.0499 0.3267 0.3267
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0106 0.0573 0.1135
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0076 0.0373 0.0504
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0759 0.5048 0.5563
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0382 0.0756
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0382 0.0421
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0079 0.039 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0011 0.0011
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0145 0.084 0.1136
Plasmodium vivax flap endonuclease 1, putative 0.0059 0.0251 0.0497
Echinococcus granulosus regulator of G protein signaling 7 0.0051 0.02 0.0271
Onchocerca volvulus 0.0033 0.0073 0.0071
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0063 0.0277 0.055
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi Phosphoglycerate kinase 0.0279 0.1757 0.1757
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0258 0.1616 0.1616
Brugia malayi jmjC domain containing protein 0.0066 0.0302 0.0302
Echinococcus multilocularis CREB binding protein 0.0022 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0147
Echinococcus multilocularis ubiquitin 0.006 0.026 0.0352
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.003 0.0053 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0129 0.0248
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0079 0.0388 0.0769
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0241 0.1502 0.2976
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0031 0.0062 0.0122
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0182 0.1093 0.1093
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.039
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0258 0.1616 0.2187
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0759 0.5048 0.5815
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0106 0.0573 0.0632
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.0756
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0182 0.1094 0.1206
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0039 0.0115 0.0155
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0145 0.084 0.1136
Echinococcus granulosus geminin 0.0374 0.2411 0.3262
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0296 0.0581
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0063 0.0277 0.0306
Echinococcus multilocularis regulator of G protein signaling 7 0.0051 0.02 0.0271
Toxoplasma gondii ImpB/MucB/SamB family protein 0.008 0.0397 0.0787
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0022 0.0022
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0128 0.0141
Schistosoma mansoni DNA helicase recq1 0.0161 0.0949 0.1442
Mycobacterium ulcerans acyl-CoA synthetase 0.0106 0.0573 0.1135
Echinococcus granulosus phosphoglycerate kinase 1 0.0759 0.5048 0.6829
Echinococcus granulosus global transcription activator snf2l2 0.0022 0.0002 0.0003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0063 0.0277 0.0545
Plasmodium vivax bromodomain protein, putative 0.0022 0.0002 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0011 0.0017
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis transcription factor Dp 1 0.017 0.1016 0.1375
Echinococcus granulosus dna polymerase eta 0.0372 0.2395 0.3239
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0194 0.1176 0.1787
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0294 0.1865 0.1865
Giardia lamblia Phosphoglycerate kinase 0.0759 0.5048 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0294 0.1865 0.1865
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Entamoeba histolytica Flap nuclease, putative 0.0059 0.0251 0.0289
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0066 0.0302 0.0598
Entamoeba histolytica acetyltransferase, GNAT family 0.013 0.0741 0.0854
Onchocerca volvulus 0.0025 0.0022 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni phosphoglycerate kinase 0.0759 0.5048 0.7671
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0163 0.0968 0.1917
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.003 0.0053 0.005
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0294 0.1865 0.2524
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0494 0.3232 0.4372
Brugia malayi 6-phosphofructokinase 0.0241 0.1502 0.1502
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0106 0.0573 0.1135
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0087 0.0443 0.0441
Leishmania major DNA damage repair protein, putative 0.008 0.0397 0.0438
Echinococcus multilocularis lysine specific demethylase 6a 0.0066 0.0302 0.0408
Echinococcus multilocularis 6 phosphofructokinase 0.0241 0.1502 0.2033
Trypanosoma cruzi Bromodomain, putative 0.0022 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0041 0.0131 0.0199
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0102 0.055 0.0836
Loa Loa (eye worm) hypothetical protein 0.0199 0.121 0.121
Schistosoma mansoni bromodomain containing 0.0022 0.0002 0.0004
Onchocerca volvulus 0.003 0.0053 0.005
Echinococcus granulosus PHD finger protein rhinoceros 0.0098 0.0517 0.0699
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0099 0.0197
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0022 0.0026
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0039 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0199 0.121 0.1333
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0011 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.056 0.0645
Echinococcus granulosus chromobox protein 1 0.0155 0.0909 0.1229
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Entamoeba histolytica Ran family GTPase 0.0024 0.0012 0.0014
Brugia malayi RNA, U transporter 1 0.0092 0.0481 0.0481
Leishmania major DNA polymerase kappa, putative 0.008 0.0397 0.0438
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0029 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Leishmania major eukaryotic translation initiation factor-like protein 0.0039 0.0115 0.0126
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0182 0.1093 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0063 0.0277 0.055
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0199 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Leishmania major phosphoglycerate kinase B, cytosolic 0.0759 0.5048 0.5563
Onchocerca volvulus 0.0106 0.0573 0.0571
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0287 0.1818 0.3601
Schistosoma mansoni hypothetical protein 0.0068 0.0316 0.0481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0147
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0023 0.0003 0.0007
Schistosoma mansoni cpg binding protein 0.0043 0.0144 0.0219
Schistosoma mansoni cellular tumor antigen P53 0.0161 0.0953 0.1448
Schistosoma mansoni bromodomain containing protein 0.0033 0.0073 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0397 0.0438
Leishmania major hypothetical protein, conserved 0.0078 0.0382 0.0421
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Leishmania major phosphoglycerate kinase C, glycosomal 0.0759 0.5048 0.5563
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0088 0.0119
Trypanosoma brucei DNA damage repair protein, putative 0.008 0.0397 0.0438
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.044
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.016 0.0942 0.094
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0022 0.0044
Plasmodium vivax bromodomain protein, putative 0.0022 0.0002 0.0005
Mycobacterium ulcerans lipase LipD 0.0078 0.0382 0.0756
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.016 0.0947 0.1281
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0031 0.0062 0.0122
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0082 0.041 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0147
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0497 0.3253 0.6445
Trichomonas vaginalis antibiotic synthetase, putative 0.0031 0.0062 0.0071
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0192 0.0211
Brugia malayi Phosphoglycerate kinase 0.0759 0.5048 0.5048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0382 0.058
Loa Loa (eye worm) hypothetical protein 0.0106 0.0573 0.0573
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Loa Loa (eye worm) hypothetical protein 0.0176 0.1057 0.1057
Schistosoma mansoni myelin transcription factor 1 myt1 0.0182 0.1093 0.1661
Brugia malayi MH2 domain containing protein 0.0259 0.1623 0.1623
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0011 0.0015
Echinococcus multilocularis flap endonuclease 1 0.0059 0.0251 0.0339
Trichomonas vaginalis set domain proteins, putative 0.0791 0.5265 0.6064
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Plasmodium falciparum DNA repair protein REV1, putative 0.008 0.0397 0.0783
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0161 0.0949 0.1284
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Brugia malayi F/Y-rich N-terminus family protein 0.0054 0.0219 0.0219
Echinococcus granulosus histone acetyltransferase KAT2B 0.0153 0.0895 0.1211
Mycobacterium ulcerans phosphoglycerate kinase 0.0759 0.5048 1
Trypanosoma brucei Bromodomain, putative 0.0022 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0002 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0022 0.0002 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0011 0.0015
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0022 0.003
Entamoeba histolytica ankyrin repeat protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) oxidoreductase 0.0031 0.0062 0.0062
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Trichomonas vaginalis rotamase, putative 0.0072 0.0345 0.0397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0199 0.023
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0279 0.1757 0.1937
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0012 0.0025
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.0115 0.0132
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0153 0.0895 0.1773
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.027 0.031
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0071 0.0078
Leishmania major hypothetical protein, conserved 0.0066 0.0302 0.0332
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0101
Entamoeba histolytica acyl-CoA synthetase, putative 0.0106 0.0573 0.066
Echinococcus multilocularis Small ubiquitin modifier 2 0.0127 0.0717 0.097
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0065 0.0296 0.0586
Echinococcus multilocularis Protein lozenge 0.0186 0.1122 0.1518
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Giardia lamblia GTOR 0.0051 0.0199 0.039
Echinococcus multilocularis segment polarity protein dishevelled 0.003 0.0053 0.0071
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Giardia lamblia PHD finger protein 15 0.0098 0.0517 0.102
Loa Loa (eye worm) hypothetical protein 0.0604 0.3986 0.3986
Loa Loa (eye worm) hypothetical protein 0.0098 0.0517 0.0517
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0022 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Plasmodium vivax importin-beta 2, putative 0.0032 0.0071 0.0141
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.039
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0076 0.037 0.05
Brugia malayi RNA binding protein 0.0194 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Plasmodium vivax bromodomain protein, putative 0.0022 0.0002 0.0005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0189 0.1146 0.1263
Brugia malayi PHD-finger family protein 0.0125 0.0704 0.0704
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0012 0.0014
Mycobacterium ulcerans DNA polymerase IV 0.0377 0.2429 0.4811
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0012 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0022 0.0044
Echinococcus granulosus flap endonuclease 1 0.0059 0.0251 0.0339
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0011 0.0011
Trypanosoma brucei unspecified product 0.0178 0.1068 0.1177
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0101
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Echinococcus multilocularis bloom syndrome protein 0.0263 0.1652 0.2235
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0145 0.084 0.1136
Echinococcus granulosus dna polymerase kappa 0.0377 0.2429 0.3286
Plasmodium falciparum small ubiquitin-related modifier 0.0127 0.0717 0.1417
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) beta-lactamase 0.0078 0.0382 0.0382
Schistosoma mansoni jumonji/arid domain-containing protein 0.0258 0.1618 0.2459
Trypanosoma brucei polo-like protein kinase 0.021 0.1286 0.1417
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0031 0.0062 0.0122
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0294 0.1865 0.2149
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0003 0.0004
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0031 0.0062 0.0122
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.0004
Trichomonas vaginalis hypothetical protein 0.0025 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0522 0.3427 0.3427
Toxoplasma gondii peptidylprolyl isomerase 0.0072 0.0345 0.0684
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Schistosoma mansoni phd/f-box containing protein 0.0066 0.0302 0.0458
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0161 0.0949 0.0949
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0039 0.0115 0.0126
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.016 0.0946 0.1874
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0192 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0129 0.0142
Leishmania major DNA polymerase eta, putative 0.0372 0.2395 0.2639
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Brugia malayi nuclear receptor NHR-88 0.0024 0.0011 0.0011
Trypanosoma cruzi ISWI complex protein 0.0068 0.0316 0.0348
Loa Loa (eye worm) glutaminase 0.0612 0.4041 0.4041
Entamoeba histolytica ubiquitin like protein 0.0127 0.0717 0.0826
Trypanosoma brucei Bromodomain factor 1 0.0022 0.0002 0.0003
Trypanosoma brucei unspecified product 0.0178 0.1068 0.1177
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0258 0.1616 0.2187
Schistosoma mansoni DNA polymerase IV / kappa 0.008 0.0397 0.0604
Leishmania major hypothetical protein, conserved 0.0022 0.0002 0.0003
Entamoeba histolytica phosphoglycerate kinase, putative 0.0759 0.5048 0.5815
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0065 0.0296 0.0341
Leishmania major acetyl-CoA synthetase, putative 0.0031 0.0062 0.0068
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) 6-phosphofructokinase 0.0241 0.1502 0.1502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Loa Loa (eye worm) phosphofructokinase 0.0241 0.1502 0.1502
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0063 0.0277 0.0277
Echinococcus granulosus lysine specific demethylase 6a 0.0066 0.0302 0.0408
Echinococcus granulosus jumonji domain containing 1A 0.0066 0.0302 0.0408
Brugia malayi jmjC domain containing protein 0.0258 0.1618 0.1618
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0065 0.0296 0.0038
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0011 0.0017
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0129 0.0142
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0148 0.0225
Loa Loa (eye worm) heterochromatin protein 1 0.0155 0.0909 0.0909
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0074 0.0357 0.0357
Leishmania major acetyl-CoA synthetase, putative 0.0031 0.0062 0.0068
Brugia malayi Bromodomain containing protein 0.0348 0.2234 0.2234
Loa Loa (eye worm) DIX domain-containing protein 0.003 0.0053 0.0053
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0637 0.4215 0.4645
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Leishmania major hypothetical protein, conserved 0.0022 0.0002 0.0003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0031 0.0062 0.0068
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0294 0.1865 0.2056
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0067 0.0133
Loa Loa (eye worm) hypothetical protein 0.0042 0.0138 0.0138
Schistosoma mansoni coup transcription factor 0.0024 0.0011 0.0017
Schistosoma mansoni hypothetical protein 0.0374 0.2411 0.3664
Brugia malayi Heterochromatin protein 1 0.0155 0.0909 0.0909
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0022 0.0026
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0031 0.0062 0.0071
Brugia malayi hypothetical protein 0.0133 0.0757 0.0757
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0059 0.0251 0.0497
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0031 0.0062 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0717 0.0826
Schistosoma mansoni tar DNA-binding protein 0.0194 0.1176 0.1787
Entamoeba histolytica acyl-CoA synthetase, putative 0.0106 0.0573 0.066
Trichomonas vaginalis chromobox protein, putative 0.0155 0.0909 0.1047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0063 0.0277 0.0545
Echinococcus multilocularis bromodomain containing protein 8 0.0022 0.0002 0.0003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.028 0.1767 0.239
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus multilocularis regulator of G protein signaling 7 0.0051 0.02 0.0271
Loa Loa (eye worm) hypothetical protein 0.0051 0.02 0.02
Onchocerca volvulus Huntingtin homolog 0.0133 0.0757 0.0755
Plasmodium vivax DNA repair protein REV1, putative 0.008 0.0397 0.0787
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0022 0.0044
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0024 0.0014 0.0016
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0003 0.0003
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0346 0.2221 0.2221
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Toxoplasma gondii hypothetical protein 0.0022 0.0002 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0022 0.0026
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0068 0.0315 0.0315
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Toxoplasma gondii propionate-CoA ligase 0.0031 0.0062 0.0122
Trichomonas vaginalis ap endonuclease, putative 0.0063 0.0277 0.032
Schistosoma mansoni methyl-cpg binding protein mbd 0.0076 0.037 0.0562
Echinococcus multilocularis expressed protein 0.0074 0.0357 0.0483
Entamoeba histolytica phosphofructokinase, putative 0.0241 0.1502 0.1731
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0106 0.0573 0.1135
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0296 0.0581
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0071 0.0141
Entamoeba histolytica bromodomain-containing protein 0.0022 0.0002 0.0003
Schistosoma mansoni ap endonuclease 0.0063 0.0277 0.0422
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0011 0.0017
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0063 0.0277 0.0375
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.1057 0.1606
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0161 0.0949 0.1284
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0637 0.4215 0.4645
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0063 0.0277 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.027 0.031
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.028 0.1767 0.239
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0015 0.0016
Trypanosoma cruzi DNA damage repair protein, putative 0.008 0.0397 0.0438
Plasmodium falciparum phosphoglycerate kinase 0.0759 0.5048 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0106 0.0573 0.0632
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0022 0.0026
Echinococcus granulosus transcription factor Dp 1 0.017 0.1016 0.1375
Schistosoma mansoni bromodomain containing protein 0.0022 0.0002 0.0004
Echinococcus multilocularis expressed protein 0.042 0.2725 0.3686
Giardia lamblia Transcription regulatory protein SNF2 0.0022 0.0002 0.0000000008989
Entamoeba histolytica acyl-coA synthetase, putative 0.0106 0.0573 0.066
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0199 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0382 0.044
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0153 0.0895 0.1773
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0161 0.0949 0.188
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0031 0.0062 0.0122
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0063 0.0277 0.0543
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) RecQ helicase 0.0263 0.1652 0.1652
Brugia malayi Pre-SET motif family protein 0.0695 0.4608 0.4608
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0073
Brugia malayi acetyltransferase, GNAT family protein 0.0494 0.3232 0.3232
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0182 0.1093 0.1479
Trypanosoma cruzi Bromodomain factor 1 0.0022 0.0002 0.0003
Echinococcus multilocularis segment polarity protein dishevelled 0.003 0.0053 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Entamoeba histolytica recQ family helicase, putative 0.0182 0.1094 0.1261
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0039 0.0115 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0063 0.0277 0.0306
Schistosoma mansoni tar DNA-binding protein 0.0194 0.1176 0.1787
Trypanosoma cruzi DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Onchocerca volvulus 0.016 0.0942 0.094
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.021 0.1286 0.174
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0088 0.0134
Loa Loa (eye worm) hypothetical protein 0.0099 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Echinococcus multilocularis chromobox protein 1 0.0155 0.0909 0.1229
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Toxoplasma gondii bromodomain-containing protein 0.0022 0.0002 0.0005
Brugia malayi Bromodomain containing protein 0.0022 0.0002 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.0063 0.0277 0.0277
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0011 0.0015
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0153 0.0895 0.1031
Brugia malayi Bromodomain containing protein 0.012 0.067 0.067
Echinococcus granulosus histone acetyltransferase MYST2 0.0182 0.1093 0.1479
Echinococcus granulosus JmjC domain containing protein 4 0.0066 0.0302 0.0408
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0382 0.0756
Toxoplasma gondii phosphofructokinase PFKII 0.0065 0.0296 0.0586
Loa Loa (eye worm) hypothetical protein 0.0204 0.1246 0.1246
Plasmodium falciparum phd finger protein, putative 0.0098 0.0517 0.102
Schistosoma mansoni acetyl-CoA synthetase 0.0031 0.0062 0.0094
Loa Loa (eye worm) hypothetical protein 0.0499 0.3267 0.3267
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0294 0.1865 0.2524
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0192 0.0211
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0011 0.0015
Giardia lamblia Sgs1 DNA helicase, putative 0.0161 0.0949 0.1876
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0241 0.1502 0.2976
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0022 0.0034
Echinococcus granulosus Bromodomain containing protein 0.0022 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Brugia malayi beta-lactamase 0.0078 0.0382 0.0382
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0241 0.1502 0.1656
Echinococcus multilocularis lysine specific demethylase 5A 0.0248 0.1547 0.2093
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0382 0.0421
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0062 0.0122
Plasmodium falciparum importin beta, putative 0.0032 0.0071 0.0136
Loa Loa (eye worm) hypothetical protein 0.0082 0.041 0.041
Echinococcus multilocularis tumor protein p63 0.1101 0.7392 1
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0032 0.0063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0258 0.1618 0.2459
Schistosoma mansoni inositol monophosphatase 0.0041 0.0129 0.0195
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0449 0.2926 0.3959
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0382 0.0756
Brugia malayi bromodomain containing protein 0.0022 0.0002 0.0002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0258 0.1616 0.2456
Schistosoma mansoni glutaminase 0.0612 0.4041 0.6141
Brugia malayi jmjC domain containing protein 0.0449 0.2926 0.2926
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0073 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1347 0.9075 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) 6-phosphofructokinase 0.0241 0.1502 0.1502
Trichomonas vaginalis phosphofructokinase, putative 0.0241 0.1502 0.1731
Schistosoma mansoni inositol monophosphatase 0.0041 0.0129 0.0195
Onchocerca volvulus 0.0791 0.5265 0.5264
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0488 0.0562
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Mycobacterium ulcerans DNA polymerase IV 0.0377 0.2429 0.4811
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0258 0.1616 0.2456
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0261 0.0261
Trichomonas vaginalis bromodomain containing protein, putative 0.0022 0.0002 0.0003
Brugia malayi mbt repeat family protein 0.016 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0315 0.2009 0.2009
Trichomonas vaginalis ap endonuclease, putative 0.0063 0.0277 0.032
Schistosoma mansoni DNA polymerase eta 0.0372 0.2395 0.3639
Onchocerca volvulus Huntingtin homolog 0.0133 0.0757 0.0755
Brugia malayi AMP-binding enzyme family protein 0.0031 0.0062 0.0062
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0022 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.0062 0.0122
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0161 0.0949 0.1284
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0129 0.0142
Trypanosoma brucei phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0128 0.0141
Schistosoma mansoni chromobox protein 0.0155 0.0909 0.1381
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.011 0.0217
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0189 0.1146 0.1263
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0022 0.003
Brugia malayi steroid hormone receptor 0.0024 0.0011 0.0011
Echinococcus multilocularis chromobox protein 1 0.0155 0.0909 0.1229
Schistosoma mansoni protein phosphatase 2C 0.0066 0.0302 0.0458
Echinococcus granulosus zinc finger protein 0.0101 0.0541 0.0732
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0072 0.0345 0.038
Loa Loa (eye worm) RNA binding protein 0.0194 0.1176 0.1176
Brugia malayi serine/threonine-protein kinase plk-2 0.021 0.1286 0.1286
Loa Loa (eye worm) hypothetical protein 0.1482 1 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0382 0.0756
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.039
Plasmodium vivax phosphoglycerate kinase, putative 0.0759 0.5048 1
Schistosoma mansoni 6-phosphofructokinase 0.0241 0.1502 0.2283
Schistosoma mansoni hypothetical protein 0.0022 0.0003 0.0004
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0759 0.5048 0.5815
Plasmodium falciparum acyl-CoA synthetase 0.0079 0.039 0.0768
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0011 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0011 0.0017
Giardia lamblia Flap structure-specific endonuclease 0.0059 0.0251 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0357 0.0411
Brugia malayi ecdysteroid receptor 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0022
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0082 0.041 0.0451
Mycobacterium ulcerans hypothetical protein 0.0106 0.0573 0.1135
Echinococcus multilocularis dnaJ subfamily B 0.0466 0.3039 0.4111
Echinococcus multilocularis Bromodomain containing protein 0.0022 0.0002 0.0003
Brugia malayi Flap endonuclease-1 0.0059 0.0251 0.0251
Leishmania major DNA polymerase kappa, putative 0.0287 0.1818 0.2003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Echinococcus multilocularis chromobox protein 2 0.0025 0.0022 0.003
Mycobacterium ulcerans hypothetical protein 0.0078 0.0382 0.0756
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0129 0.0255
Toxoplasma gondii small ubiquitin family modifier, putative 0.0127 0.0717 0.1421
Loa Loa (eye worm) CBP-B 0.0022 0.0002 0.0002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0072 0.0345 0.038
Loa Loa (eye worm) translation initiation factor 4E 0.0039 0.0115 0.0115
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.016 0.0947 0.1281
Onchocerca volvulus 0.0102 0.0546 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0194 0.1176 0.1295
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0022 0.0002 0.0003
Echinococcus granulosus bromodomain containing protein 8 0.0022 0.0002 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.1286 0.1417
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0032 0.0067 0.0074
Mycobacterium tuberculosis Conserved protein 0.0078 0.0382 0.0756
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0051 0.02 0.02
Schistosoma mansoni bromodomain containing protein 0.0296 0.1876 0.2851
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0022 0.0002 0.0003
Schistosoma mansoni sex comb on midleg homolog 0.016 0.0942 0.1432
Schistosoma mansoni eyes absent homolog 0.0099 0.0528 0.0802
Schistosoma mansoni hypothetical protein 0.0466 0.3039 0.4617
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0022 0.0026
Loa Loa (eye worm) PHD-finger family protein 0.0098 0.0517 0.0517
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0131 0.0131
Toxoplasma gondii 6-phosphofructokinase 0.0065 0.0296 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0002
Onchocerca volvulus 0.0078 0.0382 0.038
Loa Loa (eye worm) hypothetical protein 0.1482 1 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0066 0.0302 0.0598
Entamoeba histolytica hypothetical protein 0.0022 0.0002 0.0003
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0031 0.0062 0.0122
Trichomonas vaginalis hypothetical protein 0.0022 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0011 0.0015
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0109 0.0599 0.1187
Brugia malayi Protein cec-1. 0.0025 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0044
Onchocerca volvulus 0.0031 0.0062 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0207 0.1269 0.1399
Echinococcus granulosus phd:f box containing protein 0.0066 0.0302 0.0408
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0066 0.0302 0.0332
Echinococcus multilocularis geminin 0.0374 0.2411 0.3262
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0296 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0377 0.2429 0.2676
Loa Loa (eye worm) hypothetical protein 0.0041 0.0131 0.0131
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0161 0.0949 0.0949
Onchocerca volvulus Alhambra homolog 0.0098 0.0517 0.0515
Toxoplasma gondii hypothetical protein 0.003 0.0053 0.0104
Echinococcus multilocularis bromodomain containing 2 0.0022 0.0002 0.0003
Schistosoma mansoni jumonji domain containing protein 0.0384 0.2477 0.3763
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0161 0.0949 0.1284
Loa Loa (eye worm) hypothetical protein 0.0078 0.0382 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0443 0.051
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0294 0.1865 0.2835
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0001 0.0001
Leishmania major ATP-dependent phosphofructokinase 0.0241 0.1502 0.1656
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Echinococcus granulosus Pleckstrin G protein interacting region 0.003 0.0053 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0073 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0126
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0066 0.0302 0.0332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0062 0.0122
Echinococcus granulosus tumor protein p63 0.1101 0.7392 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0349 0.053
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0093 0.0142
Plasmodium vivax SET domain protein, putative 0.01 0.0536 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.021 0.1286 0.1954
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0261 0.0261
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0161 0.0949 0.188
Trichomonas vaginalis phosphofructokinase, putative 0.0241 0.1502 0.1731
Loa Loa (eye worm) hypothetical protein 0.0161 0.0953 0.0953
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0011 0.0015
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0199 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0067
Loa Loa (eye worm) bromodomain containing protein 0.0091 0.047 0.047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Entamoeba histolytica serine/threonine protein kinase, putative 0.021 0.1286 0.1481
Trypanosoma brucei phosphoglycerate kinase 0.0759 0.5048 0.5563
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0279 0.1757 0.1937
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0082 0.041 0.0811
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Entamoeba histolytica hypothetical protein 0.0026 0.0029 0.0033
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0129 0.0174
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0022 0.003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0258 0.1616 0.3202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0011 0.0011
Trichomonas vaginalis lymphoid specific helicase, putative 0.0022 0.0002 0.0003
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0261 0.0261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0709 0.4709 0.9328
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0102 0.055 0.0745
Brugia malayi ImpB/MucB/SamB family protein 0.0258 0.1616 0.1616
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0011 0.0015
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.003 0.0053 0.0053
Trypanosoma brucei DNA polymerase eta, putative 0.0372 0.2395 0.2639
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0012 0.002
Schistosoma mansoni hypothetical protein 0.0098 0.0517 0.0786
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0382 0.044
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0071 0.0096
Loa Loa (eye worm) flap endonuclease-1 0.0059 0.0251 0.0251
Echinococcus granulosus importin subunit beta 1 0.0032 0.0071 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0194 0.1176 0.1787
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0062
Schistosoma mansoni zinc finger protein 0.0101 0.0541 0.0822
Loa Loa (eye worm) runx1 0.0186 0.1122 0.1122
Loa Loa (eye worm) hypothetical protein 0.006 0.026 0.026
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0063 0.0277 0.0375
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0031 0.0062 0.0062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) mbt repeat family protein 0.016 0.0942 0.0942
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0129 0.0174
Trypanosoma cruzi small ubiquitin protein, putative 0.0127 0.0717 0.079
Loa Loa (eye worm) MBCTL1 0.0182 0.1093 0.1093
Trypanosoma brucei ISWI complex protein 0.0068 0.0316 0.0348
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0192 0.0375
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0011
Brugia malayi ATPase, AAA family protein 0.0022 0.0002 0.0002
Echinococcus multilocularis phosphoglycerate kinase 1 0.0759 0.5048 0.6829
Leishmania major DNA polymerase eta, putative 0.0194 0.1176 0.1295
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0011 0.0015
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0088 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0011 0.0011
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0099 0.0197
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0022 0.0044
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0145 0.084 0.1136
Echinococcus multilocularis snurportin 1 0.0346 0.2221 0.3004
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0031 0.0062 0.0122
Leishmania major hypothetical protein, conserved 0.0068 0.0316 0.0348
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0022 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0011 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0382 0.0756
Schistosoma mansoni helicase 0.0022 0.0002 0.0004
Mycobacterium ulcerans beta-lactamase 0.0078 0.0382 0.0756
Echinococcus granulosus dnaJ subfamily B 0.0466 0.3039 0.4111
Trichomonas vaginalis ran, putative 0.0024 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0133 0.0757 0.0757
Brugia malayi hypothetical protein 0.0025 0.0022 0.0022
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.016 0.0942 0.1432
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0039 0.0115 0.0126
Trichomonas vaginalis rotamase, putative 0.0074 0.0357 0.0411
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0022 0.0044
Brugia malayi jmjC domain containing protein 0.0066 0.0302 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1286 0.1481
Schistosoma mansoni flap endonuclease-1 0.0053 0.0212 0.0322
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0031 0.0062 0.0068

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.9362 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Confirmation of Cherrypicks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.0918 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Cherrypicks in WT IDH1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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