Detailed information for compound 1226603

Basic information

Technical information
  • TDR Targets ID: 1226603
  • Name: 4-methyl-1-[2-[2-(2-phenylphenoxy)ethoxy]ethy l]piperidine
  • MW: 339.471 | Formula: C22H29NO2
  • H donors: 0 H acceptors: 0 LogP: 4.69 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CCN(CC1)CCOCCOc1ccccc1c1ccccc1
  • InChi: 1S/C22H29NO2/c1-19-11-13-23(14-12-19)15-16-24-17-18-25-22-10-6-5-9-21(22)20-7-3-2-4-8-20/h2-10,19H,11-18H2,1H3
  • InChiKey: CVVWFILCNQEOER-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-{2-[2-(2-biphenylyloxy)ethoxy]ethyl}-4-methylpiperidine
  • MLS000666711
  • SMR000271286

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lamin A/C Starlite/ChEMBL No references
Mus musculus transient receptor potential cation channel, subfamily C, member 4 Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Transient-receptor-potential like protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Transient receptor potential-gamma protein, putative Get druggable targets OG5_128782 All targets in OG5_128782
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus multilocularis TRP (transient receptor potential) channel Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus TRP transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni transient receptor potential channel 4 Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Echinococcus multilocularis short transient receptor potential channel 6 transient receptor potential cation channel, subfamily C, member 4 890 aa 799 aa 31.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Echinococcus granulosus neuroglian 0.0024 0.0239 0.0422
Loa Loa (eye worm) hypothetical protein 0.003 0.0411 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein kinase, putative 0.0115 0.278 0.9422
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0945 0.1762
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) cytochrome P450 family protein 0.0109 0.2608 0.2608
Echinococcus multilocularis protein tyrosine kinase 0.0069 0.1494 0.2802
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Echinococcus granulosus insulin receptor 0.0069 0.1494 0.2802
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Entamoeba histolytica hypothetical protein 0.0043 0.079 0.2458
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.1494 0.2704
Echinococcus granulosus N chimaerin 0.0064 0.1372 0.2571
Loa Loa (eye worm) hypothetical protein 0.0025 0.0276 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0069 0.1494 0.5286
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.056 0.1032
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Echinococcus granulosus activated cdc42 kinase 1 0.0069 0.1494 0.2802
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0501 0.0794
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis neuroglian 0.0024 0.0239 0.0422
Entamoeba histolytica protein kinase domain containing protein 0.007 0.153 0.5048
Onchocerca volvulus 0.0069 0.1494 0.1125
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0105
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0069 0.1494 0.2802
Loa Loa (eye worm) TK/ABL protein kinase 0.0121 0.2945 0.2945
Brugia malayi hypothetical protein 0.0043 0.079 0.073
Trypanosoma brucei protein kinase, putative 0.007 0.153 0.5357
Echinococcus granulosus tyrosine protein kinase Src42A 0.0121 0.2945 0.5556
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0115 0.278 0.9422
Loa Loa (eye worm) hypothetical protein 0.0092 0.2151 0.2151
Entamoeba histolytica SH2 domain containing protein 0.0052 0.103 0.3296
Echinococcus granulosus SH2 domain containing protein 7 0.0052 0.103 0.1922
Trichomonas vaginalis AGC family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica hypothetical protein, conserved 0.0069 0.1494 0.492
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0073 0.1604 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0052 0.103 0.103
Echinococcus granulosus kinase suppressor of Ras 1 0.0069 0.1494 0.2802
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis RNA directed DNA polymerase 0.008 0.1809 0.3401
Schistosoma mansoni transient receptor potential channel 0.0078 0.1741 0.318
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus granulosus geminin 0.0205 0.5287 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Echinococcus granulosus retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Echinococcus granulosus aurora kinase A 0.0115 0.278 0.5243
Echinococcus granulosus protein kinase c epsilon type 0.0033 0.0501 0.0919
Schistosoma mansoni tensin 0.0052 0.103 0.1812
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0073 0.1604 0.5812
Giardia lamblia Kinase, NEK 0.0069 0.1494 0.4991
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Loa Loa (eye worm) hypothetical protein 0.008 0.1809 0.1809
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus epidermal growth factor receptor 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein kinase Blk 0.0121 0.2945 0.5556
Schistosoma mansoni protein kinase 0.007 0.153 0.2774
Loa Loa (eye worm) serine/threonine protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Echinococcus multilocularis protein kinase c iota type 0.0031 0.043 0.0784
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus receptor type guanylyl cyclase 0.0069 0.1494 0.2802
Brugia malayi Variant SH3 domain containing protein 0.0064 0.1372 0.1315
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.1494 0.1494
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0121 0.2945 0.5556
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0109 0.2608 1
Trichomonas vaginalis protein kinase atn1, putative 0.0069 0.1494 0.5286
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Entamoeba histolytica protein kinase , putative 0.0115 0.278 0.9422
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0069 0.1494 0.2704
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) TK/CSK protein kinase 0.0069 0.1494 0.1494
Echinococcus granulosus ephrin type A receptor 4 A 0.0069 0.1494 0.2802
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.079 0.1468
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0069 0.1494 0.5222
Echinococcus granulosus defective proboscis extension response 0.0019 0.0105 0.0167
Plasmodium vivax hypothetical protein, conserved 0.0035 0.056 0.1357
Brugia malayi SRC-1 0.0121 0.2945 0.2899
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0073 0.1604 0.5812
Loa Loa (eye worm) TK/ACK protein kinase 0.0069 0.1494 0.1494
Echinococcus multilocularis protein KINase family member (kin 25) 0.0069 0.1494 0.2802
Entamoeba histolytica tyrosin kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus SH2 motif 0.0052 0.103 0.1922
Loa Loa (eye worm) hypothetical protein 0.0033 0.0487 0.0487
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.153 0.5133
Echinococcus granulosus expressed conserved protein 0.0052 0.103 0.1922
Echinococcus granulosus lamin dm0 0.0033 0.0487 0.0892
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.056 0.1755
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0073 0.1604 1
Brugia malayi Protein kinase c protein 2 0.0096 0.2259 0.2208
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0064 0.1372 0.2571
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0073 0.1604 1
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Giardia lamblia PHD finger protein 15 0.0035 0.056 0.1357
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Echinococcus multilocularis tensin 0.0052 0.103 0.1922
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.103 0.103
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.1741 0.3272
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Onchocerca volvulus Alhambra homolog 0.0035 0.056 0.0082
Echinococcus granulosus dual specificity testis-specific protein kinase 0.007 0.153 0.2872
Leishmania major protein kinase, putative 0.0115 0.278 1
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0767 0.1424
Echinococcus multilocularis Immunoglobulin 0.0019 0.0105 0.0167
Loa Loa (eye worm) AUR protein kinase 0.0115 0.278 0.278
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.007 0.153 0.5357
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Echinococcus granulosus intermediate filament protein 0.0033 0.0487 0.0892
Echinococcus granulosus protein kinase c iota type 0.0031 0.043 0.0784
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Plasmodium falciparum protein kinase, putative 0.0069 0.1494 0.4991
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Plasmodium falciparum protein kinase, putative 0.007 0.153 0.5133
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0487 0.0425
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0115 0.278 1
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Brugia malayi Protein kinase domain containing protein 0.0018 0.0088 0.0023
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Cytochrome P450 family protein 0.0109 0.2608 0.2559
Loa Loa (eye worm) cytochrome P450 family protein 0.0109 0.2608 0.2608
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0025 0.0276 0.0492
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein kinase csk 0.0069 0.1494 0.2802
Leishmania major protein kinase, putative 0.007 0.153 0.5133
Loa Loa (eye worm) TK/Met protein kinase 0.0069 0.1494 0.1494
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Echinococcus granulosus tyrosine protein kinase Src42A 0.0052 0.103 0.1922
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi PHD-finger family protein 0.0035 0.056 0.0499
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Echinococcus granulosus Protein kinase C brain isozyme 0.0113 0.2732 0.5151
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0212 0.0588
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Schistosoma mansoni ap endonuclease 0.0023 0.0212 0.0238
Trichomonas vaginalis protein tyrosine kinase, putative 0.0069 0.1494 0.5286
Echinococcus multilocularis tyrosine protein kinase Srms 0.0121 0.2945 0.5556
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0073 0.1604 0.5812
Schistosoma mansoni lamin 0.0033 0.0487 0.0767
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus tyrosine protein kinase pr2 0.0069 0.1494 0.2802
Echinococcus multilocularis c src tyrosine kinase 0.0121 0.2945 0.5556
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0073 0.1604 0.5633
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.1741 0.3272
Loa Loa (eye worm) cytochrome P450 family protein 0.0229 0.5974 0.5974
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0052 0.103 0.0607
Entamoeba histolytica hypothetical protein 0.0069 0.1497 0.4931
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0052 0.103 0.0971
Brugia malayi Tensin 0.0052 0.103 0.0971
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Onchocerca volvulus 0.0069 0.1494 0.1125
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0069 0.1494 0.5286
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0069 0.1494 0.5222
Schistosoma mansoni vav2 0.0064 0.1372 0.2469
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0069 0.1494 0.2704
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0064 0.1372 0.2469
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Schistosoma mansoni serine/threonine RGC 0.0069 0.1494 0.2704
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0073 0.1604 0.5812
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Brugia malayi Fibronectin type III domain containing protein 0.0019 0.0105 0.004
Echinococcus multilocularis tyrosine protein kinase pr2 0.0069 0.1494 0.2802
Trypanosoma cruzi protein kinase, putative 0.0069 0.1494 0.4991
Echinococcus granulosus RNA directed DNA polymerase 0.008 0.1809 0.3401
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0069 0.1494 0.2802
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0115 0.278 0.9422
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0121 0.2945 0.5556
Leishmania major cytochrome p450-like protein 0.0073 0.1604 0.5422
Echinococcus multilocularis lamin dm0 0.0033 0.0487 0.0892
Loa Loa (eye worm) SRC-1 0.0121 0.2945 0.2945
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0767 0.1424
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.056 0.0909
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0073 0.1628 0.3057
Brugia malayi p70 ribosomal S6 kinase beta 0.0018 0.0088 0.0023
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.079 0.1351
Echinococcus granulosus suppressor of cytokine signaling 6 0.0052 0.103 0.1922
Entamoeba histolytica tyrosin kinase, putative 0.0069 0.1494 0.492
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0073 0.1604 1
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0069 0.1494 0.1494
Loa Loa (eye worm) TK/ROR protein kinase 0.0073 0.1628 0.1628
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0073 0.1628 0.3057
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Brugia malayi Variant SH3 domain containing protein 0.0052 0.103 0.0971
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni hypothetical protein 0.0035 0.056 0.0909
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0073 0.1604 0.5812
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Brugia malayi hypothetical protein 0.0069 0.1494 0.1438
Echinococcus granulosus tyrosine protein kinase HCK 0.0069 0.1494 0.2802
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0105
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Schistosoma mansoni jumonji domain containing protein 0.0092 0.2134 0.3935
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0073 0.1604 0.5812
Brugia malayi Furin-like cysteine rich region family protein 0.0069 0.1494 0.1438
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0052 0.103 0.1922
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Echinococcus multilocularis lamin 0.0033 0.0487 0.0892
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein kinase, putative 0.0115 0.278 0.9422
Brugia malayi C-terminal src kinase protein 1 0.0069 0.1494 0.1438
Echinococcus granulosus retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Giardia lamblia Kinase, NEK 0.0069 0.1494 0.4991
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Protein kinase domain containing protein 0.0121 0.2945 0.2899
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Echinococcus granulosus protein kinase C gamma type 0.0101 0.239 0.4503
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Brugia malayi Cytochrome P450 family protein 0.0229 0.5974 0.5948
Echinococcus multilocularis signal transduction protein lnk realted 0.0052 0.103 0.1922
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Trypanosoma brucei Flagellum attachment zone protein 20 0.0069 0.1494 0.5222
Echinococcus granulosus tyrosine protein kinase csk 0.0069 0.1494 0.2802
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0069 0.1494 0.1438
Toxoplasma gondii exonuclease III APE 0.0023 0.0212 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0069 0.1494 0.1438
Brugia malayi Protein kinase domain containing protein 0.0018 0.0088 0.0023
Echinococcus multilocularis tyrosine kinase 0.0121 0.2945 0.5556
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Variant SH3 domain containing protein 0.0055 0.1101 0.1043
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis tyrosine protein kinase shark 0.0121 0.2945 0.5556
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Echinococcus multilocularis transfer RNA-Thr 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0052 0.103 0.1922
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0212 0.0212
Schistosoma mansoni atypical protein kinase C 0.0031 0.043 0.0658
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0069 0.1494 0.2802
Plasmodium falciparum tyrosine kinase-like protein 0.0069 0.1494 0.4991
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Onchocerca volvulus 0.0052 0.103 0.0607
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0121 0.2945 0.5556
Echinococcus granulosus tyrosine protein kinase 0.0069 0.1494 0.2802
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus cytochrome P450 2K1 0.0073 0.1604 0.3012
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0069 0.1494 0.2802
Echinococcus granulosus natriuretic peptide receptor 1 0.0069 0.1494 0.2802
Echinococcus multilocularis geminin 0.0205 0.5287 1
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0212 0.0588
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0055 0.1101 0.1101
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) TK/EPH protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis SH2 domain containing protein 7 0.0052 0.103 0.1922
Brugia malayi hypothetical protein 0.0052 0.103 0.0971
Giardia lamblia Kinase 0.0069 0.1494 0.4991
Loa Loa (eye worm) AGC/NDR protein kinase 0.0018 0.0088 0.0088
Echinococcus multilocularis protein kinase 0.0069 0.1494 0.2802
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) hypothetical protein 0.0032 0.047 0.047
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Echinococcus granulosus tyrosine protein kinase csk 0.0069 0.1494 0.2802
Brugia malayi Guanylyl cyclase protein 23 0.0069 0.1494 0.1438
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Schistosoma mansoni hypothetical protein 0.0069 0.1494 0.2704
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Schistosoma mansoni protein tyrosine kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) cytochrome P450 0.0073 0.1604 0.1604
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0069 0.1494 0.2802
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0019 0.0105 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Plasmodium vivax tyrosine kinase-like protein, putative 0.0069 0.1494 0.4991
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Leishmania major protein kinase, putative 0.0069 0.1494 0.4991
Schistosoma mansoni growth factor receptor-bound protein 0.0052 0.103 0.1812
Schistosoma mansoni tensin-related 0.0052 0.103 0.1812
Entamoeba histolytica hypothetical protein 0.0069 0.1497 0.4931
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0073 0.1604 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0069 0.1494 0.1494
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0767 0.0767
Trichomonas vaginalis TK family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.1836 0.3361
Schistosoma mansoni cell adhesion molecule 0.0025 0.0276 0.0362
Schistosoma mansoni ap endonuclease 0.0023 0.0212 0.0238
Echinococcus granulosus hypothetical protein 0.0052 0.103 0.1922
Entamoeba histolytica receptor protein kinase, putative 0.0069 0.1494 0.492
Brugia malayi STAT protein, DNA binding domain containing protein 0.0052 0.103 0.0971
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0073 0.1604 0.5812
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0212 0.037
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0073 0.1604 0.5422
Brugia malayi protein-tyrosine kinase 0.0121 0.2945 0.2899
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0069 0.1494 0.5222
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0069 0.1494 0.1438
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0069 0.1494 0.2802
Echinococcus multilocularis epidermal growth factor receptor 0.0069 0.1494 0.2802
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Trypanosoma cruzi cytochrome P450, putative 0.0109 0.2608 0.9328
Brugia malayi bone morphogenetic protein type 1 receptor 0.0069 0.1494 0.1438
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Onchocerca volvulus 0.0052 0.103 0.0607
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.006 0.1262 0.1262
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0121 0.2945 0.5496
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni shc transforming protein 0.0052 0.103 0.1812
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi ephrin receptor 1 precursor 0.0069 0.1494 0.1438
Echinococcus granulosus signal transduction protein lnk realted 0.0052 0.103 0.1922
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.056 0.1755
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Echinococcus multilocularis musashi 0.0033 0.0487 0.0892
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) CYP4Cod1 0.0109 0.2608 0.2608
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Giardia lamblia Aurora kinase 0.0115 0.278 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0073 0.1604 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0069 0.1494 0.1494
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0065 0.0065
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Echinococcus granulosus tyrosine protein kinase csk 0.0069 0.1494 0.2802
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Onchocerca volvulus 0.0121 0.2945 0.2747
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Echinococcus multilocularis NCK adaptor protein 0.0052 0.103 0.1922
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis protein kinase c epsilon type 0.0033 0.0501 0.0919
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Onchocerca volvulus 0.0069 0.1494 0.1125
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.1606 0.1606
Brugia malayi Receptor family ligand binding region containing protein 0.0069 0.1494 0.1438
Echinococcus granulosus NCK adaptor protein 0.0052 0.103 0.1922
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Loa Loa (eye worm) hypothetical protein 0.0036 0.0581 0.0581
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis FL cytokine receptor 0.0069 0.1494 0.2802
Echinococcus multilocularis growth factor receptor bound protein 2 0.0052 0.103 0.1922
Trypanosoma cruzi protein kinase, putative 0.0069 0.1494 0.4991
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.2795 0.5272
Toxoplasma gondii protein kinase domain-containing protein 0.0069 0.1494 0.5222
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.2732 0.5085
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Brugia malayi Protein kinase domain containing protein 0.0018 0.0088 0.0023
Echinococcus multilocularis tyrosine protein kinase Abl 0.0121 0.2945 0.5556
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Echinococcus multilocularis ephrin type A receptor 4 A 0.0069 0.1494 0.2802
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Loa Loa (eye worm) TK/RYK protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0121 0.2945 0.5556
Entamoeba histolytica receptor protein kinase, putative 0.0069 0.1494 0.492
Schistosoma mansoni protein kinase 0.007 0.153 0.2774
Loa Loa (eye worm) AUR protein kinase 0.0115 0.278 0.278
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0121 0.2945 0.5556
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.2739 0.5166
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Brugia malayi Cytochrome P450 family protein 0.0109 0.2608 0.2559
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0073 0.1604 0.5812
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0121 0.2945 0.5556
Loa Loa (eye worm) TK/EGFR protein kinase 0.0069 0.1494 0.1494
Entamoeba histolytica protein kinase, putative 0.0053 0.1066 0.3424
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0073 0.1604 0.5422
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0073 0.1604 0.5812
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0018 0.0088 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0073 0.1604 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0073 0.1604 1
Loa Loa (eye worm) STAT protein 0.0052 0.103 0.103
Echinococcus multilocularis serine threonine protein kinase 0.0101 0.239 0.4503
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0073 0.1604 0.5812
Entamoeba histolytica hypothetical protein 0.0043 0.079 0.2458
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis roundabout 2 0.003 0.0411 0.0747
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) TK protein kinase 0.0121 0.2945 0.2945
Brugia malayi Cytochrome P450 family protein 0.0073 0.1604 0.155
Echinococcus multilocularis SH2 motif 0.0052 0.103 0.1922
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni signal transduction protein lnk-related 0.0052 0.103 0.1812
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis serine:threonine protein kinase N2 0.0018 0.0088 0.0135
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Echinococcus multilocularis activin receptor type 0.007 0.153 0.2872
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0108
Echinococcus multilocularis Immunoglobulin 0.0019 0.0105 0.0167
Echinococcus granulosus growth factor receptor bound protein 2 0.0052 0.103 0.1922
Echinococcus multilocularis 0.0052 0.103 0.1922
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni tyrosine kinase 0.008 0.18 0.3292
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Echinococcus multilocularis tensin 0.0052 0.103 0.1922
Toxoplasma gondii aurora kinase 0.0115 0.278 1
Brugia malayi serine/threonine kinase 12 0.0115 0.278 0.2733
Brugia malayi tRNA modification GTPase TrmE family protein 0.0052 0.103 0.0971
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.2848 0.5373
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0069 0.1494 0.2802
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0069 0.1494 0.1125
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Trichomonas vaginalis AGC family protein kinase 0.0115 0.278 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0019 0.0105 0.0167
Toxoplasma gondii cytochrome p450 superfamily protein 0.0073 0.1604 0.5633
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0212 0.5
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0018 0.0088 0.0088
Plasmodium falciparum tyrosine kinase-like protein 0.0069 0.1494 0.4991
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.278 0.5178
Toxoplasma gondii STE kinase 0.0069 0.1494 0.5222
Mycobacterium leprae putative cytochrome p450 0.0073 0.1604 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Brugia malayi serine/threonine protein kinase 6 0.0115 0.278 0.2733
Schistosoma mansoni cytochrome P450 0.0073 0.1604 0.2916
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Loa Loa (eye worm) TK/FAK protein kinase 0.0069 0.1494 0.1494
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0069 0.1494 0.1438
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.2739 0.5166
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus granulosus tyrosine protein kinase Lyn 0.0122 0.2982 0.5626
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Echinococcus granulosus tensin 0.0052 0.103 0.1922
Echinococcus granulosus SHC transforming protein 3 0.0052 0.103 0.1922
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0105
Echinococcus multilocularis kinase suppressor of Ras 1 0.0069 0.1494 0.2802
Echinococcus granulosus tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Loa Loa (eye worm) hypothetical protein 0.004 0.0685 0.0685
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0069 0.1494 0.1438
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0073 0.1604 1
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis SHC transforming protein 3 0.0052 0.103 0.1922
Schistosoma mansoni lamin 0.0033 0.0487 0.0767
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0019 0.0105 0.0032
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0069 0.1497 0.4931
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus integrin linked protein kinase 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0052 0.103 0.1922
Echinococcus multilocularis tyrosine protein kinase csk 0.0069 0.1494 0.2802
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0073 0.1604 0.5422
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0794 0.1476
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0767 0.1306
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Entamoeba histolytica ankyrin repeat protein 0.0069 0.1494 0.492
Leishmania major hypothetical protein, conserved 0.0069 0.1494 0.4991
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.1494 0.2704
Schistosoma mansoni tensin 0.0052 0.103 0.1812
Schistosoma mansoni protein kinase 0.007 0.153 0.2774
Entamoeba histolytica hypothetical protein 0.0043 0.079 0.2458
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni suppressor of cytokine signaling 0.0052 0.103 0.1812
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Schistosoma mansoni intermediate filament proteins 0.0033 0.0487 0.0767
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0069 0.1494 0.1494
Brugia malayi cytokine inducible SH2-containing protein 5 0.0052 0.103 0.0971
Onchocerca volvulus 0.0052 0.103 0.0607
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0487 0.0487
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni ephrin receptor 0.0069 0.1494 0.2704
Schistosoma mansoni nck2/grb4 0.0052 0.103 0.1812
Onchocerca volvulus 0.0069 0.1494 0.1125
Entamoeba histolytica protein kinase, putative 0.0069 0.1497 0.4931
Echinococcus granulosus tyrosine protein kinase ABL1 0.0121 0.2945 0.5556
Schistosoma mansoni tensin 0.0052 0.103 0.1812
Echinococcus multilocularis SH2 motif 0.0052 0.103 0.1922
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0073 0.1604 1
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0064 0.1372 0.1372
Echinococcus multilocularis aurora kinase A 0.0115 0.278 0.5243
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0121 0.2945 0.5556
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0018 0.0088 0.0088
Echinococcus granulosus fibroblast growth factor receptor 4 0.0069 0.1494 0.2802
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0073 0.1604 1
Schistosoma mansoni transient receptor potential channel 0.0117 0.2848 0.5309
Onchocerca volvulus Tyrosine kinase homolog 0.0353 0.9436 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0052 0.103 0.1922
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0069 0.1494 0.5286
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis heat shock protein 70 0.0069 0.1494 0.2802
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis protein kinase 0.0069 0.1494 0.2802
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus tyrosine protein kinase shark 0.0121 0.2945 0.5556
Echinococcus multilocularis activated cdc42 kinase 1 0.0069 0.1494 0.2802
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0069 0.1494 0.2802
Loa Loa (eye worm) TK/INSR protein kinase 0.0069 0.1494 0.1494
Brugia malayi Tyrosine-protein kinase abl-1 0.0121 0.2945 0.2899
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Plasmodium falciparum phd finger protein, putative 0.0035 0.056 0.1357
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Plasmodium vivax tyrosine kinase-like protein, putative 0.0069 0.1494 0.4991
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.056 0.056
Schistosoma mansoni hypothetical protein 0.0043 0.079 0.1351
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0121 0.2945 0.5556
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Brugia malayi SH2 domain containing protein 0.0121 0.2945 0.2899
Schistosoma mansoni GTPase activating protein 0.0052 0.103 0.1812
Brugia malayi integrin-linked kinase 0.0069 0.1494 0.1438
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0069 0.1494 0.1438
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0052 0.103 0.1812
Brugia malayi cytochrome P450 0.0073 0.1604 0.155
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0121 0.2945 0.5556
Schistosoma mansoni vesicular amine transporter 0.0023 0.0214 0.0242
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0212 0.037
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.007 0.153 0.5357
Brugia malayi Protein kinase domain containing protein 0.0121 0.2945 0.2899
Echinococcus multilocularis receptor type guanylyl cyclase 0.0069 0.1494 0.2802
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0069 0.1494 0.1494
Echinococcus granulosus protein tyrosine kinase 0.0069 0.1494 0.2802
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Schistosoma mansoni tensin-related 0.0052 0.103 0.1812
Giardia lamblia Protein 21.1 0.0069 0.1494 0.4991
Loa Loa (eye worm) hypothetical protein 0.003 0.0411 0.0411
Trichomonas vaginalis AGC family protein kinase 0.0115 0.278 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0052 0.103 0.1922
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Brugia malayi Hr1 repeat family protein 0.0018 0.0088 0.0023
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.1494 0.1494
Brugia malayi Variant SH3 domain containing protein 0.0052 0.103 0.0971
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Onchocerca volvulus 0.0069 0.1494 0.1125
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0069 0.1494 0.2802
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.2848 0.5309
Echinococcus granulosus protein kinase 0.0069 0.1494 0.2802
Onchocerca volvulus 0.0121 0.2945 0.2747
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0017
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Onchocerca volvulus 0.0121 0.2945 0.2747
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0069 0.1494 0.2802
Echinococcus multilocularis peregrin 0.0035 0.056 0.1032
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0073 0.1604 0.5812
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0105
Plasmodium vivax protein kinase, putative 0.0069 0.1494 0.4991
Schistosoma mansoni growth factor receptor-bound protein 0.0052 0.103 0.1812
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis tyrosine protein kinase csk 0.0069 0.1494 0.2802
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0052 0.103 0.1922
Echinococcus granulosus raf serine:threonine protein kinase 0.0081 0.1836 0.3451
Trichomonas vaginalis AGC family protein kinase 0.0115 0.278 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0073 0.1604 0.5422
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0084 0.1917 0.1917
Entamoeba histolytica tyrosin kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0069 0.1494 0.2802
Onchocerca volvulus 0.0052 0.103 0.0607
Echinococcus multilocularis serine:threonine protein kinase N2 0.0018 0.0088 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Brugia malayi protein kinase C II. 0.0033 0.0501 0.0439
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0069 0.1494 0.1494
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0073 0.1604 1
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0069 0.1494 0.2704
Loa Loa (eye worm) hypothetical protein 0.0121 0.2945 0.2945
Echinococcus granulosus tyrosine protein kinase Blk 0.0121 0.2945 0.5556
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Onchocerca volvulus 0.0069 0.1494 0.1125
Echinococcus multilocularis serine:threonine protein kinase 38 0.0018 0.0088 0.0135
Loa Loa (eye worm) AGC/PKN protein kinase 0.0018 0.0088 0.0088
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.1741 0.3272
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Trichomonas vaginalis STE family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.278 0.9422
Brugia malayi hypothetical protein 0.0019 0.0105 0.004
Echinococcus granulosus tyrosine kinase 0.0069 0.1494 0.2802
Entamoeba histolytica hypothetical protein 0.0043 0.079 0.2458
Brugia malayi Raf kinase 0.0069 0.1494 0.1438
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0073 0.1604 0.5812
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0052 0.103 0.1922
Brugia malayi SH2 domain containing protein 0.0121 0.2945 0.2899
Echinococcus granulosus serine:threonine protein kinase N2 0.0018 0.0088 0.0135
Entamoeba histolytica cysteine surface protein, putative 0.0069 0.1494 0.492
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis tyrosine protein kinase csk 0.0069 0.1494 0.2802
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0105
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.056 0.1032
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.2848 0.5373
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0069 0.1494 0.2802
Schistosoma mansoni SH2A 0.0052 0.103 0.1812
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Onchocerca volvulus 0.0052 0.103 0.0607
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0069 0.1494 0.2802
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0053 0.1066 0.3424
Echinococcus granulosus epidermal growth factor receptor 0.0069 0.1494 0.2802
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.079 0.1468
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.153 0.5133
Brugia malayi intermediate filament protein 0.0033 0.0487 0.0425
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus multilocularis epidermal growth factor receptor 0.0069 0.1494 0.2802
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0088 0.0134
Schistosoma mansoni suppressor of cytokine signaling 0.0052 0.103 0.1812
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Echinococcus granulosus retinal guanylyl cyclase 2 0.0069 0.1494 0.2802
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0212 0.0434
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0121 0.2945 0.5556
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0018 0.0088 0.0135
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0212 0.046
Echinococcus granulosus tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0069 0.1494 0.1494
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0073 0.1604 1
Brugia malayi Protein kinase domain containing protein 0.0121 0.2945 0.2899
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.008 0.1809 0.3401
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.103 0.103
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0073 0.1604 0.5812
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Schistosoma mansoni protein kinase 0.0115 0.278 0.5178
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0212 0.0148
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.0117 0.2848 0.2848
Entamoeba histolytica hypothetical protein 0.0069 0.1497 0.4931
Echinococcus multilocularis dual specificity testis specific protein kinase 0.007 0.153 0.2872
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0052 0.103 0.103
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0018 0.0088 0.0135
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0073 0.1604 0.5812
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0069 0.1494 0.1125
Onchocerca volvulus 0.0069 0.1494 0.1125
Onchocerca volvulus 0.0121 0.2945 0.2747
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.1494 0.1494
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0121 0.2945 0.5556
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0052 0.103 0.1922
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus twitchin 0.0025 0.0275 0.0491
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0115 0.278 0.5243
Echinococcus granulosus NDR protein kinase 0.0018 0.0088 0.0135
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0064 0.1372 0.2571
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Brugia malayi Protein kinase domain containing protein 0.0121 0.2945 0.2899
Brugia malayi Bromodomain containing protein 0.0035 0.056 0.0499
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus suppressor of cytokine signaling 7 0.0052 0.103 0.1922
Onchocerca volvulus 0.0069 0.1494 0.1125
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0069 0.1494 0.492
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Brugia malayi Tyrosine-protein kinase PR2 0.0069 0.1494 0.1438
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0113 0.2732 0.5151
Echinococcus multilocularis integrin linked protein kinase 0.0069 0.1494 0.2802
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis 0.0073 0.1604 0.3012
Trypanosoma cruzi aurora B kinase, putative 0.0115 0.278 1
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0052 0.103 0.1922
Schistosoma mansoni tyrosine kinase 0.0121 0.2945 0.5496
Echinococcus multilocularis tyrosine protein kinase 0.0069 0.1494 0.2802
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0018 0.0088 0.0135
Mycobacterium leprae Conserved hypothetical protein 0.0073 0.1604 0.5
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0069 0.1494 0.2704
Loa Loa (eye worm) AGC/AKT protein kinase 0.0018 0.0088 0.0088
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0069 0.1494 0.2802
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0105 0.004
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0064 0.1372 0.2469
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0794 0.0734
Brugia malayi hypothetical protein 0.0121 0.2945 0.2899
Echinococcus multilocularis N chimaerin 0.0064 0.1372 0.2571
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Echinococcus granulosus tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0073 0.1604 1
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0073 0.1604 0.5812
Entamoeba histolytica ankyrin repeat protein 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.0044 0.0794 0.0794
Echinococcus multilocularis natriuretic peptide receptor 1 0.0069 0.1494 0.2802
Schistosoma mansoni nephrin 0.0024 0.0239 0.0291
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.1741 0.3272
Schistosoma mansoni tyrosine protein kinase 0.0069 0.1494 0.2704
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Onchocerca volvulus 0.0121 0.2945 0.2747
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0487 0.0487
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0073 0.1604 0.5812
Echinococcus multilocularis raf serine:threonine protein kinase 0.0081 0.1836 0.3451
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0073 0.1604 1
Schistosoma mansoni hypothetical protein 0.0205 0.5287 1
Onchocerca volvulus 0.0069 0.1494 0.1125
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0052 0.103 0.1922
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis insulin receptor 0.0069 0.1494 0.2802
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) AUR protein kinase 0.0115 0.278 0.278
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0018 0.0088 0.0135
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0073 0.1604 0.5812
Echinococcus granulosus peregrin 0.0035 0.056 0.1032
Trypanosoma cruzi cytochrome P450, putative 0.0109 0.2608 0.9328
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Trichomonas vaginalis AGC family protein kinase 0.0115 0.278 1
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Plasmodium falciparum protein kinase, putative 0.0069 0.1494 0.4991
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.1494 0.5286
Loa Loa (eye worm) hypothetical protein 0.0035 0.056 0.056
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0212 0.5
Echinococcus granulosus activin receptor type 0.007 0.153 0.2872
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0794 0.1476
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0945 0.1762
Brugia malayi Protein kinase domain containing protein 0.0121 0.2945 0.2899
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0052 0.103 0.1812
Entamoeba histolytica protein kinase, putative 0.0069 0.1494 0.492
Plasmodium falciparum serine/threonine protein kinase, putative 0.0115 0.278 1
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0115 0.278 0.5243
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0052 0.103 0.103
Toxoplasma gondii protein kinase 0.0069 0.1494 0.5222
Loa Loa (eye worm) protein kinase domain-containing protein 0.0069 0.1494 0.1494
Brugia malayi jmjC domain containing protein 0.0115 0.2795 0.2748
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0073 0.1604 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0374 1 1
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni tyrosine kinase 0.0069 0.1494 0.2704
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Loa Loa (eye worm) hypothetical protein 0.0052 0.103 0.103
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Leishmania major cytochrome p450-like protein 0.0109 0.2608 0.9328
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0052 0.103 0.1922
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0052 0.103 0.0607
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0073 0.1604 1
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Schistosoma mansoni hypothetical protein 0.0073 0.1604 0.2916
Echinococcus multilocularis tyrosine protein kinase HCK 0.0069 0.1494 0.2802
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0121 0.2945 0.5556
Brugia malayi Sex muscle abnormal protein 5 0.0052 0.103 0.0971
Brugia malayi serine/threonine-protein kinase 6 0.0115 0.278 0.2733
Echinococcus granulosus activated cdc42 kinase 1 0.0069 0.1494 0.2802
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0069 0.1494 0.2802
Brugia malayi Protein kinase domain containing protein 0.0069 0.1494 0.1438
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0073 0.1604 1
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus Immunoglobulin 0.0019 0.0105 0.0167
Leishmania major cytochrome p450-like protein 0.0073 0.1604 0.5422
Echinococcus granulosus c src tyrosine kinase 0.0121 0.2945 0.5556
Loa Loa (eye worm) TK protein kinase 0.0069 0.1494 0.1494
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Brugia malayi hypothetical protein 0.0069 0.1494 0.1438
Trypanosoma brucei cytochrome P450, putative 0.0109 0.2608 0.9359
Echinococcus multilocularis tyrosine kinase 0.0069 0.1494 0.2802
Entamoeba histolytica tyrosine kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.2795 0.5272
Echinococcus granulosus lamin 0.0033 0.0487 0.0892
Brugia malayi jmjC domain containing protein 0.0043 0.0767 0.0707
Echinococcus granulosus tyrosine kinase 0.0121 0.2945 0.5556
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0018 0.0088 0.0135
Echinococcus granulosus tyrosine protein kinase Src64B 0.0121 0.2945 0.5556
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0121 0.2945 1
Entamoeba histolytica serine/threonine kinase, putative 0.0069 0.1494 0.492
Brugia malayi SH2 domain containing protein 0.0052 0.103 0.0971
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.2732 0.5085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0033 0.0501 0.0501
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Echinococcus granulosus roundabout 2 0.003 0.0411 0.0747
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0073 0.1604 0.5812
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.1494 0.2704
Loa Loa (eye worm) TK protein kinase 0.0073 0.1628 0.1628
Onchocerca volvulus 0.028 0.7386 0.7709
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.1494 0.492
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0073 0.1604 0.5812
Schistosoma mansoni ephrin receptor 0.0069 0.1494 0.2704
Schistosoma mansoni hypothetical protein 0.0052 0.103 0.1812
Schistosoma mansoni protein kinase 0.0069 0.1494 0.2704
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0115 0.278 0.9422
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Trypanosoma brucei Pseudokinase, putative 0.0069 0.1494 0.5222
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0069 0.1494 0.2802
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0069 0.1494 0.2704
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0073 0.1604 1
Entamoeba histolytica tyrosin kinase, putative 0.0069 0.1494 0.492
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0121 0.2945 0.5556
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0052 0.103 0.103
Echinococcus granulosus SH2 motif 0.0052 0.103 0.1922
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.1628 0.1573
Onchocerca volvulus 0.0121 0.2945 0.2747
Schistosoma mansoni hypothetical protein 0.0205 0.5287 1
Schistosoma mansoni hypothetical protein 0.0052 0.103 0.1812
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0073 0.1604 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0121 0.2945 0.5556
Echinococcus multilocularis SH2 motif 0.0052 0.103 0.1922
Echinococcus granulosus SH2 domain containing adapter protein F 0.0052 0.103 0.1922
Brugia malayi RhoGAP domain containing protein 0.0064 0.1372 0.1315
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1494
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.2945 0.2945
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0018 0.0088 0.0088
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0767 0.1306
Echinococcus granulosus tyrosine kinase 0.0121 0.2945 0.5556
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0052 0.103 0.1922
Loa Loa (eye worm) hypothetical protein 0.0074 0.1632 0.1632
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0069 0.1494 0.2802
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0069 0.1494 0.2704
Echinococcus granulosus tyrosine protein kinase Srms 0.0121 0.2945 0.5556
Schistosoma mansoni transient receptor potential channel 0.0078 0.1741 0.318
Onchocerca volvulus 0.0052 0.103 0.0607
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0069 0.1494 0.492
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.1494 0.1494
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0073 0.1604 0.5812
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.103 0.103
Trichomonas vaginalis TKL family protein kinase 0.0069 0.1494 0.5286
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0018 0.0088 0.0135
Schistosoma mansoni adapter molecule crk 0.0052 0.103 0.1812
Entamoeba histolytica hypothetical protein 0.0069 0.1494 0.492
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0052 0.103 0.1812
Trypanosoma brucei aurora B kinase 0.0115 0.278 1

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 2.9853 uM PUBCHEM_BIOASSAY: Confirmation dose response assay for compounds that inhibit transient receptor potential cation channel C4 (TRPC4). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2247, AID2256] ChEMBL. No reference
Potency (functional) 0.0224 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.4467 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.7308 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.3109 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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