Detailed information for compound 1237097

Basic information

Technical information
  • TDR Targets ID: 1237097
  • Name: [2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl] (E)-3-(3-methoxyphenyl)prop-2-enoate
  • MW: 351.396 | Formula: C21H21NO4
  • H donors: 0 H acceptors: 2 LogP: 3.65 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)/C=C/C(=O)OCC(=O)N1CCCc2c1cccc2
  • InChi: 1S/C21H21NO4/c1-25-18-9-4-6-16(14-18)11-12-21(24)26-15-20(23)22-13-5-8-17-7-2-3-10-19(17)22/h2-4,6-7,9-12,14H,5,8,13,15H2,1H3/b12-11+
  • InChiKey: AJDFFJCZLFMYLB-VAWYXSNFSA-N  

Network

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Synonyms

  • [2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxo-ethyl] (E)-3-(3-methoxyphenyl)prop-2-enoate
  • (E)-3-(3-methoxyphenyl)prop-2-enoic acid [2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl] ester
  • (E)-3-(3-methoxyphenyl)acrylic acid [2-(3,4-dihydro-2H-quinolin-1-yl)-2-keto-ethyl] ester
  • ZINC07506881

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0025 0.0075 0.011
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.0021 0.0046 0.0094
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0037 0.0054
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0237 0.1615 0.1615
Loa Loa (eye worm) steroid hormone receptor 0.0237 0.1615 0.2392
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0011
Schistosoma mansoni cytochrome P450 0.0043 0.0205 0.0205
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0005 0.0005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0678 0.0678
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0205 0.0901
Echinococcus granulosus neuroligin 0.0035 0.0149 0.0149
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0149 0.0149
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.2282
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0102 0.031
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.2857 0.2857
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.0064
Trichomonas vaginalis cdc25b, putative 0.0056 0.0306 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0077 0.019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.0064
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0211 0.0954
Brugia malayi N-terminal motif family protein 0.0184 0.1232 0.1824
Echinococcus multilocularis muscleblind protein 0.0152 0.1002 0.1002
Echinococcus multilocularis Estrogen regulated protein EP45 0.0017 0.0018 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0176 0.0176
Schistosoma mansoni zinc finger protein 0.0021 0.0046 0.0046
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.068 0.3177
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0183 0.1223 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.1223 0.1811
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Echinococcus granulosus hypothetical protein 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0205 0.0922
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0059 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0075 0.0552
Plasmodium falciparum thioredoxin reductase 0.0047 0.024 0.1912
Onchocerca volvulus 0.0035 0.0149 0.0453
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) FAD binding domain-containing protein 0.0034 0.014 0.0207
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0237 0.1615 0.2392
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0636 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0598 0.0598
Mycobacterium ulcerans carboxylesterase, LipT 0.0306 0.2119 1
Onchocerca volvulus 0.0019 0.0034 0.0104
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0112 0.0707 0.0707
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0237 0.1615 0.1615
Brugia malayi glutathione transferase 0.0027 0.009 0.0134
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0476 0.0476
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0077 0.019
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0062 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0211 0.0933
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.1223 0.3684
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0033
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0017 0.0017
Brugia malayi nuclear hormone receptor family member odr-7 0.0112 0.0707 0.1047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0137 0.0249
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Brugia malayi neuropeptide F receptor 0.0015 0.0005 0.0007
Mycobacterium ulcerans hydrolase 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0109 0.0161
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0205 0.1669
Mycobacterium ulcerans arylsulfatase AtsB 0.0017 0.0019 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0267 0.0769
Schistosoma mansoni zinc finger protein 0.0015 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0017 0.0018 0.0054
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0376 0.0557
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0109 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.1218 0.3667
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0022 0.0033
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.001 0.0011
Brugia malayi serpin (BmSERPIN) 0.0017 0.0018 0.0026
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0209 0.0209
Brugia malayi larval opioid receptor 0.0015 0.0005 0.0007
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0202 0.0569
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0237 0.1615 0.2392
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0015 0.0007 0.0007
Onchocerca volvulus Bile acid receptor homolog 0.0237 0.1615 0.4902
Schistosoma mansoni voltage-gated cation channel 0.0078 0.0465 0.0465
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0042 0.0062
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0029 0.0109 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0245 0.0702
Onchocerca volvulus 0.0056 0.0306 0.0928
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0118 0.0755 0.0755
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0095 0.0589 0.0872
Echinococcus multilocularis GPCR, family 2 0.008 0.0476 0.0476
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0077 0.019
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0485 0.0718
Echinococcus multilocularis voltage dependent calcium channel 0.0078 0.0465 0.0465
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0322 0.2631
Brugia malayi serpin 0.0017 0.0018 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0359 0.109
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0011
Brugia malayi prostaglandin transporter 0.0028 0.0102 0.0151
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0413 0.1891
Onchocerca volvulus Putative nachr subunit 0.0019 0.0034 0.0104
Echinococcus multilocularis glutathione S-transferase 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0168 0.0248
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0205 0.0375
Trypanosoma brucei carbonic anhydrase-like protein 0.0129 0.0831 0.1547
Brugia malayi Rhodanese-like domain containing protein 0.0056 0.0306 0.0453
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0183 0.1223 0.1223
Mycobacterium leprae putative cytochrome p450 0.0043 0.0205 0.2026
Onchocerca volvulus 0.0028 0.0102 0.031
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Brugia malayi Serpin protein 6 0.0017 0.0018 0.0026
Schistosoma mansoni histamine h1 receptor 0.0015 0.0005 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0125 0.0804 0.1191
Echinococcus multilocularis pikachurin 0.0095 0.0589 0.0589
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0205 0.0922
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0021 0.0047 0.0327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0035 0.0149 0.0453
Brugia malayi serpin 0.0017 0.0018 0.0026
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0035 0.0149 0.0409
Onchocerca volvulus 0.0094 0.0577 0.1751
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0005 0.0007
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0005 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0176 0.0492
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Trichomonas vaginalis rotamase, putative 0.0034 0.0143 0.039
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0253 0.1733 0.1733
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0376 0.0376
Echinococcus multilocularis neuroligin 0.0035 0.0149 0.0149
Echinococcus granulosus serotonin transporter 0.009 0.0552 0.0552
Loa Loa (eye worm) serpin protein 6 0.0017 0.0018 0.0026
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0034 0.0034
Echinococcus granulosus single minded 2 0.0071 0.0413 0.0413
Toxoplasma gondii thioredoxin reductase 0.0047 0.024 0.1956
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Mycobacterium ulcerans arylsulfatase, AslA 0.0017 0.0019 0.0018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0005 0.0005
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0112 0.0707 0.0707
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0146 0.0146
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0359 0.0532
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0183 0.1223 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0598 0.1112
Brugia malayi Serotonin receptor 0.0015 0.0005 0.0007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0328 0.0328
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0015 0.0064
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0102 0.0151
Brugia malayi RNA recognition motif domain containing protein 0.0253 0.1733 0.2566
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0205 0.0375
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Onchocerca volvulus 0.0015 0.0005 0.0015
Schistosoma mansoni cpg binding protein 0.0032 0.0129 0.0129
Brugia malayi MAP kinase sur-1 0.0051 0.0267 0.0396
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus cpg binding protein 0.0032 0.0129 0.0129
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0102 0.0831
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.0047 0.0243
Schistosoma mansoni DNA helicase recq1 0.0017 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.1185 0.8494 0.8494
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0094 0.0577 0.0854
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.024 0.024
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0017 0.0019 0.0012
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0068 0.0068
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.1912 0.9018
Loa Loa (eye worm) hypothetical protein 0.0184 0.1232 0.1824
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Plasmodium vivax glutathione S-transferase, putative 0.0118 0.0755 0.6148
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0022 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0185 0.0273
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0037 0.0296
Onchocerca volvulus 0.0081 0.0482 0.1462
Loa Loa (eye worm) acetylcholinesterase 1 0.0035 0.0149 0.0221
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0485 0.0485
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0062 0.0221
Brugia malayi flavodoxin family protein 0.0021 0.0047 0.007
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0376 0.0696
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0267 0.0492
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0005 0.0005
Plasmodium falciparum polyprenol reductase, putative 0.0183 0.1223 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0376 0.0696
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0183 0.1223 0.3684
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0017 0.0017
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.002
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0459 0.0851
Schistosoma mansoni tyrosinase precursor 0.0094 0.0577 0.0577
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0267 0.0492
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Toxoplasma gondii serpin (serine proteinase inhibitor) superfamily protein 0.0017 0.0018 0.014
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0598 0.1112
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.001 0.001
Loa Loa (eye worm) serpin 0.0017 0.0018 0.0026
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Echinococcus granulosus Estrogen regulated protein EP45 0.0017 0.0018 0.0018
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0211 0.0211
Brugia malayi Dopamine receptor protein 1 0.0015 0.0005 0.0007
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0205 0.0922
Loa Loa (eye worm) hypothetical protein 0.0043 0.0209 0.0309
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0005 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0353 0.0353
Schistosoma mansoni myosin xvIII 0.0015 0.0005 0.0005
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0179 0.0179
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0411 0.2882 0.4268
Brugia malayi Muscleblind-like protein 0.0152 0.1002 0.1483
Onchocerca volvulus 0.0081 0.0485 0.1472
Echinococcus multilocularis peroxidasin 0.0064 0.0359 0.0359
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0129 0.0831 0.1547
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0035 0.0149 0.0149
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0037 0.0296
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0267 0.0267
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.2282
Loa Loa (eye worm) hypothetical protein 0.0054 0.0291 0.0431
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0112 0.0707 0.0707
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0102 0.0151
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0056 0.0306 0.0306
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Leishmania major cytochrome P450 reductase, putative 0.0048 0.0246 0.0453
Brugia malayi FAD binding domain containing protein 0.0054 0.0291 0.0431
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0062 0.4093
Brugia malayi PAS domain containing protein 0.0096 0.0594 0.088
Schistosoma mansoni tar DNA-binding protein 0.0253 0.1733 0.1733
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0112 0.0707 0.0707
Schistosoma mansoni diflavin oxidoreductase 0.0027 0.0092 0.0092
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0343 0.0633
Loa Loa (eye worm) hypothetical protein 0.0094 0.0577 0.0854
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0176 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0129 0.0831 0.1547
Echinococcus granulosus geminin 0.1185 0.8494 0.8494
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0306 0.0453
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0034 0.0051
Brugia malayi Death domain containing protein 0.0014 0.00000002395 0.000000035461
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0413 0.0611
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0328 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0077 0.019
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0205 0.0901
Brugia malayi hypothetical protein 0.0112 0.0707 0.1047
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0205 0.0922
Brugia malayi serpin 0.0017 0.0018 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0054
Plasmodium falciparum carbonic anhydrase 0.0029 0.0109 0.0836
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0005 0.0005
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0077 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0195 0.0356
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.1523
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Entamoeba histolytica hypothetical protein 0.0023 0.0062 0.0363
Toxoplasma gondii hypothetical protein 0.0015 0.0007 0.0055
Echinococcus multilocularis carboxylesterase 5A 0.0035 0.0149 0.0149
Trypanosoma cruzi MFS transporter, putative 0.0028 0.0102 0.0183
Schistosoma mansoni hypothetical protein 0.008 0.0476 0.0476
Brugia malayi Fli-1 protein 0.0224 0.1523 0.2255
Schistosoma mansoni ap endonuclease 0.0039 0.0176 0.0176
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0125 0.0804 0.0804
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0054 0.0291 0.0537
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0176 0.0261
Onchocerca volvulus 0.0017 0.0018 0.0054
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0005 0.0005
Schistosoma mansoni intermediate filament proteins 0.0081 0.0482 0.0482
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0125 0.0804 0.1191
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0311 0.1408
Echinococcus granulosus serine protease inhibitor 0.0017 0.0018 0.0018
Brugia malayi hypothetical protein 0.0125 0.0804 0.1191
Mycobacterium tuberculosis Possible hydrolase 0.0017 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.021 0.0311
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0034 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0211 0.0599
Leishmania major cytochrome p450-like protein 0.0043 0.0205 0.0375
Echinococcus granulosus serine protease inhibitor 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0015 0.0005 0.0015
Onchocerca volvulus 0.0028 0.0102 0.031
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Schistosoma mansoni nuclear receptor nhr-48 0.0112 0.0707 0.0707
Onchocerca volvulus 0.0019 0.0034 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0077 0.019
Toxoplasma gondii transporter, cation channel family protein 0.0016 0.0015 0.0118
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0202 0.0299
Echinococcus granulosus expressed protein 0.0034 0.0143 0.0143
Brugia malayi CXXC zinc finger family protein 0.0029 0.0104 0.0154
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0146 0.0146
Loa Loa (eye worm) solute carrier family 6 member 4 0.009 0.0552 0.0818
Schistosoma mansoni hypothetical protein 0.0173 0.115 0.115
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0937 0.0937
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0429 0.0429
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0112 0.0707 0.2146
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0125 0.0804 0.1191
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0176 0.139
Toxoplasma gondii ABC1 family protein 0.0043 0.0211 0.1724
Schistosoma mansoni rotamase 0.0034 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Onchocerca volvulus 0.0019 0.0037 0.0112
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0078 0.0465 0.0688
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0095 0.0589 0.0589
Schistosoma mansoni neuroligin 3 (S09 family) 0.0035 0.0149 0.0149
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0336 0.2739
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0209 0.0209
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.0047 0.0098
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0005 0.0005
Echinococcus granulosus plasminogen activator inhibitor 2 0.0017 0.0018 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0253 0.1733 0.1733
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0129 0.0831 0.0831
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0161
Loa Loa (eye worm) fli-1 protein 0.0224 0.1523 0.2255
Onchocerca volvulus 0.0028 0.0102 0.031
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0485 0.0485
Schistosoma mansoni cpg binding protein 0.0029 0.0104 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0076 0.0449 0.0449
Brugia malayi PHD-finger family protein 0.0026 0.0084 0.0125
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0343 0.0999
Brugia malayi Rhodanese-like domain containing protein 0.0056 0.0306 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0005 0.0007
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0005 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.001
Plasmodium vivax SET domain protein, putative 0.006 0.0328 0.2638
Mycobacterium leprae Probable lipase LipE 0.0043 0.0211 0.2122
Echinococcus multilocularis nuclear receptor nhr 48 0.0112 0.0707 0.0707
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0267 0.0267
Loa Loa (eye worm) calcium channel 0.0078 0.0465 0.0688
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0005
Brugia malayi nuclear receptor RXR 0.0125 0.0804 0.1191
Loa Loa (eye worm) hypothetical protein 0.01 0.0625 0.0925
Brugia malayi Serotonin receptor 0.0015 0.0005 0.0007
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium ulcerans lipase LipD 0.0043 0.0211 0.0933
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0176 0.0787
Echinococcus granulosus slit 2 protein 0.0104 0.0649 0.0649
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0034 0.0051
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0017 0.0019 0.0012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.068 0.3177
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0005 0.0007
Loa Loa (eye worm) CYP4Cod1 0.0078 0.0459 0.0679
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Trichomonas vaginalis sulfite reductase, putative 0.0054 0.0291 0.0842
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0005
Echinococcus granulosus survival motor neuron protein 1 0.0945 0.6754 0.6754
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus granulosus neuropeptide receptor 0.0015 0.0005 0.0005
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0183 0.1223 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Brugia malayi serpin 0.0017 0.0018 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0143 0.039
Toxoplasma gondii MAPEG family protein 0.0109 0.0685 0.5596
Onchocerca volvulus 0.0183 0.1223 0.3712
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0075 0.0131
Echinococcus granulosus lamin dm0 0.0081 0.0482 0.0482
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0149 0.0149
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0037 0.0054
Echinococcus granulosus follistatin 0.0019 0.0037 0.0037
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0174 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0237 0.1615 0.2392
Echinococcus multilocularis carbonic anhydrase II 0.0129 0.0831 0.0831
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0205 0.0922
Giardia lamblia Sgs1 DNA helicase, putative 0.0017 0.0022 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0104 0.0154
Loa Loa (eye worm) RecQ helicase 0.0042 0.0202 0.0299
Echinococcus granulosus carbonic anhydrase 0.0029 0.0109 0.0109
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0112 0.0707 0.0707
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0176 0.0322
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0161
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0143 0.0212
Schistosoma mansoni adenoreceptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0075 0.0131
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0359 0.0532
Schistosoma mansoni survival motor neuron protein 0.0193 0.1295 0.1295
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0083 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0237 0.1615 0.1615
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0035 0.0149 0.0453
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0037 0.0164 0.1292
Onchocerca volvulus 0.0015 0.0005 0.0015
Brugia malayi polk-prov protein 0.0038 0.017 0.0252
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0011
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0146 0.1062
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0005 0.0015
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0034 0.0034
Echinococcus multilocularis lamin dm0 0.0081 0.0482 0.0482
Onchocerca volvulus 0.0029 0.0104 0.0315
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0205 0.0922
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0209 0.059
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0015 0.0005 0.0015
Trichomonas vaginalis esterase, putative 0.0043 0.0211 0.0599
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0103 0.0784
Leishmania major p450 reductase, putative 0.0054 0.0291 0.0537
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0205 0.0375
Plasmodium falciparum glutathione S-transferase 0.0027 0.009 0.0683
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0476 0.0476
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi flavodoxin family protein 0.0054 0.0291 0.0431
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.00000002395 0.00000002395
Echinococcus multilocularis protein dispatched 1 0.0049 0.0253 0.0253
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0434 0.3044 0.3044
Echinococcus multilocularis follistatin 0.0019 0.0037 0.0037
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0413 0.0413
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Echinococcus multilocularis zinc finger protein 0.0021 0.0046 0.0046
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0034 0.0051
Brugia malayi putative neuropeptide receptor 0.0015 0.0005 0.0007
Brugia malayi hypothetical protein 0.0015 0.0007 0.0011
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0359 0.0532
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0117 0.0211
Echinococcus multilocularis glutathione S transferase 0.0092 0.056 0.056
Echinococcus multilocularis somatostatin receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Brugia malayi Ets-domain containing protein 0.0074 0.0432 0.0639
Loa Loa (eye worm) cytochrome P450 0.0043 0.0205 0.0303
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0146 0.0216
Brugia malayi EGF-like domain containing protein 0.0104 0.0649 0.0961
Schistosoma mansoni hypothetical protein 0.1185 0.8494 0.8494
Entamoeba histolytica rodhanase-like domain containing protein 0.0056 0.0306 0.2389
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.009 0.0552 0.0552
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0237 0.1615 0.1615
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0179 0.0179
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0359 0.109
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0005 0.0005
Schistosoma mansoni serpin 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0211 0.0954
Trypanosoma brucei DNA polymerase eta, putative 0.0034 0.0146 0.0265
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0176 0.0261
Schistosoma mansoni nuclear receptor 0.0112 0.0707 0.0707
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi steroid hormone receptor 0.0237 0.1615 0.2392
Echinococcus multilocularis acetylcholinesterase 0.0035 0.0149 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0055
Brugia malayi AKH receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0028
Brugia malayi isocitrate dehydrogenase 0.0016 0.001 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0328 0.0328
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0007 0.0007
Echinococcus granulosus pikachurin 0.0095 0.0589 0.0589
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.0047 0.0098
Loa Loa (eye worm) tyrosinase 1 0.0094 0.0577 0.0854
Brugia malayi conserved hypotetical protein 0.0112 0.0707 0.1047
Echinococcus granulosus acetylcholinesterase 0.0035 0.0149 0.0149
Loa Loa (eye worm) carbonic anhydrase 3 0.0129 0.0831 0.123
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.00000002395 0.00000002395
Brugia malayi tailless protein 0.0112 0.0707 0.1047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0047 0.0327
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.3684
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0237 0.1615 0.2392
Brugia malayi beta-lactamase family protein 0.0043 0.0211 0.0313
Onchocerca volvulus 0.0015 0.0005 0.0015
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0768 0.3593
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.115 0.1702
Brugia malayi CHE-14 protein 0.0043 0.0209 0.0309
Loa Loa (eye worm) nuclear hormone receptor 0.0112 0.0707 0.1047
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0034 0.0034
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.068 0.3177
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) beta-lactamase 0.0043 0.0211 0.0313
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0017 0.0022 0.0121
Schistosoma mansoni thyroid hormone receptor 0.0365 0.2547 0.2547
Echinococcus granulosus agrin 0.0019 0.0037 0.0037
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0205 0.0901
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0078 0.0465 0.0465
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0476 0.0705
Echinococcus granulosus somatostatin receptor 0.0015 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.0043 0.0211 0.0933
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0011
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0054 0.0291 0.0537
Loa Loa (eye worm) hypothetical protein 0.0125 0.0804 0.1191
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0237 0.1615 0.1615
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.002
Brugia malayi Cation transporter family protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi Ets-domain containing protein 0.0074 0.0432 0.0639
Loa Loa (eye worm) serpin 0.0017 0.0018 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Echinococcus multilocularis Estrogen regulated protein EP45 0.0017 0.0018 0.0018
Onchocerca volvulus 0.009 0.0552 0.1677
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0151 0.0151
Schistosoma mansoni RAR-like nuclear receptor 0.0237 0.1615 0.1615
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0476 0.0476
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0146 0.0643
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0202 0.0569
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0918 0.0918
Brugia malayi Glutathione S-transferase 4 0.0021 0.0046 0.0068
Brugia malayi hypothetical protein 0.0945 0.6754 1
Brugia malayi Cytochrome P450 family protein 0.008 0.0478 0.0708
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0015 0.0064
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.01 0.0814
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0205 0.0901
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0034 0.0051
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.002
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.2282
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.001 0.001
Onchocerca volvulus 0.0021 0.0046 0.0139
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0183 0.1223 1
Brugia malayi Sulfatase family protein 0.0017 0.0019 0.0028
Schistosoma mansoni cytochrome P450 reductase 0.0054 0.0291 0.0291
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0005
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0137 0.1118
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0183 0.1223 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0068
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0237 0.1615 0.2392
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0625 0.0925
Onchocerca volvulus 0.0015 0.0005 0.0015
Brugia malayi nuclear receptor NHR-88 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0408 0.2857 0.2857
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0083 0.0147
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0205 0.0901
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0151 0.0151
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0267 0.0492
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0146 0.0216
Brugia malayi nuclear hormone receptor 0.0112 0.0707 0.1047
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0205 0.0901
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0918 0.0918
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0005 0.0005
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0129 0.0831 0.123
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0336 0.062
Echinococcus multilocularis BC026374 protein (S09 family) 0.0035 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.009 0.0552 0.0818
Echinococcus granulosus nAChR subunit 0.0019 0.0034 0.0034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0237 0.1615 0.1615
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0056 0.0306 0.0306
Loa Loa (eye worm) flavodoxin family protein 0.0021 0.0047 0.007
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0205 0.0901
Brugia malayi SPARC precursor 0.0019 0.0037 0.0054
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.008 0.0476 0.0476
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0077 0.019
Loa Loa (eye worm) hypothetical protein 0.0038 0.017 0.0252
Schistosoma mansoni coup transcription factor 0.0237 0.1615 0.1615
Echinococcus multilocularis expressed protein 0.0019 0.0037 0.0037
Echinococcus multilocularis neurogenic locus notch protein 0.0095 0.0589 0.0589
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0021 0.0047 0.008
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0005 0.0005
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0005 0.0005
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0005 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.0118
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0048 0.0242 0.0445
Onchocerca volvulus 0.0035 0.0149 0.0453
Trypanosoma brucei unspecified product 0.0024 0.0068 0.012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0034 0.0051
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus granulosus intermediate filament protein 0.0081 0.0482 0.0482
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0112 0.0707 0.1047
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0237 0.1615 0.1615
Onchocerca volvulus 0.0071 0.0413 0.1253
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0376 0.2971
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0211 0.0313
Brugia malayi intermediate filament protein 0.0081 0.0482 0.0713
Echinococcus granulosus carbonic anhydrase II 0.0129 0.0831 0.0831
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0152 0.1002 0.1483
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0237 0.1615 0.2392
Onchocerca volvulus 0.0064 0.0359 0.109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0109 0.0109
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0015 0.0005 0.0015
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0253 0.1733 0.2566
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Echinococcus multilocularis glutathione S transferase 0.0027 0.009 0.009
Brugia malayi FAD binding domain containing protein 0.0034 0.014 0.0207
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0015 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.015 0.0222
Brugia malayi nuclear receptor NHR-88 0.0112 0.0707 0.1047
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Entamoeba histolytica hypothetical protein 0.0108 0.0678 0.5474
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0005 0.0005
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0267 0.2086
Brugia malayi hypothetical protein 0.0028 0.0102 0.0151
Brugia malayi Steroid receptor seven-up type 2 0.0237 0.1615 0.2392
Plasmodium falciparum glutathione reductase 0.0047 0.024 0.1912
Schistosoma mansoni organic anion transporter 0.0028 0.0102 0.0102
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0205 0.0375
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0011
Onchocerca volvulus 0.0015 0.0007 0.0022
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0143 0.0212
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0626 0.4441 0.6576
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus para nitrobenzyl esterase 0.0035 0.0149 0.0149
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0343 0.0999
Brugia malayi serpin precursor 0.0017 0.0018 0.0026
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0005 0.0015
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0056 0.0306 0.0887
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0125 0.0804 0.0804
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0237 0.1615 0.2392
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0059 0.0103
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0005 0.0005
Echinococcus granulosus allatostatin A receptor 0.0015 0.0005 0.0005
Echinococcus granulosus carbonic anhydrase 0.0029 0.0109 0.0109
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0308 0.0308
Onchocerca volvulus 0.0015 0.0005 0.0015
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0109 0.0109
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0598 0.0598
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0064 0.0359 0.109
Leishmania major C-8 sterol isomerase-like protein 0.0751 0.5347 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0033 0.0137 0.0137
Trypanosoma cruzi p450 reductase, putative 0.0054 0.0291 0.0537
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.115 0.349
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0237 0.1615 0.2392
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0062 0.0498
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0183 0.1223 0.2282
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi Peroxidasin 0.0064 0.0359 0.0532
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus BC026374 protein S09 family 0.0035 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0253 0.173 0.2561
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0019 0.0018
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0034 0.0051
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0094 0.0577 0.0854
Loa Loa (eye worm) hypothetical protein 0.0125 0.0804 0.1191
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0078 0.0465 0.0465
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0211 0.0599
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0359 0.0532
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0005
Schistosoma mansoni steroid hormone receptor ad4bp 0.0237 0.1615 0.1615
Brugia malayi hypothetical protein 0.0028 0.0102 0.0151
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0022
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0029 0.0109 0.0161
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0459 0.0679
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.024 0.0441
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Loa Loa (eye worm) voltage-dependent calcium channel 0.0016 0.0015 0.0022
Loa Loa (eye worm) ShTK domain-containing protein 0.0094 0.0577 0.0854
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.024 0.0355
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0017 0.0022 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0005 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0598 0.4816
Schistosoma mansoni single-minded 0.0096 0.0594 0.0594
Mycobacterium tuberculosis Carboxylesterase LipT 0.0306 0.2119 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0034 0.0034
Schistosoma mansoni follistatin 0.0019 0.0037 0.0037
Onchocerca volvulus 0.0112 0.0707 0.2146
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0034 0.0051
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0149 0.0149
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0328 0.2678
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Echinococcus multilocularis synaptic glycoprotein sc2 0.0183 0.1223 0.1223
Entamoeba histolytica rodhanase-like domain containing protein 0.0056 0.0306 0.2389
Loa Loa (eye worm) hypothetical protein 0.0069 0.0397 0.0588
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0209 0.0309
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0034 0.0051
Mycobacterium tuberculosis Probable reductase 0.0108 0.068 0.3177
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0077 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Plasmodium falciparum glutathione reductase 0.0016 0.0015 0.0064
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0054 0.0291 0.0291
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Brugia malayi ShTK domain containing protein 0.0094 0.0577 0.0854
Brugia malayi hypothetical protein 0.024 0.164 0.2428
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.0047 0.0098
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0211 0.0954
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0037 0.0054
Brugia malayi Melatonin receptor type 1A 0.0015 0.0005 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0054 0.0291 0.1312
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0042 0.0197 0.0197
Brugia malayi follicle stimulating hormone receptor 0.0474 0.3338 0.4942
Leishmania major protein kinase, putative 0.0026 0.0083 0.0147
Echinococcus multilocularis musashi 0.0081 0.0482 0.0482
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0021 0.0047 0.008
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0078 0.0465 0.0465
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0095 0.0589 0.0872
Schistosoma mansoni sodium/chloride dependent transporter 0.009 0.0552 0.0552
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0359 0.0532
Echinococcus granulosus fmrfamide receptor 0.0015 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0918 0.0918
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0237 0.1615 0.1615
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) carboxylesterase 0.0035 0.0149 0.0221
Echinococcus granulosus histone lysine methyltransferase setb 0.0076 0.0449 0.0449
Echinococcus multilocularis serotonin receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Onchocerca volvulus 0.0028 0.0102 0.031
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0205 0.0901
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0267 0.0396
Schistosoma mansoni retinoic acid receptor RXR 0.0434 0.3044 0.3044
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0022 0.0177
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0062 0.0243
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0005 0.0005
Brugia malayi G-protein coupled receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.002
Brugia malayi hypothetical protein 0.0017 0.0018 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0077 0.019
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0176 0.139
Echinococcus granulosus glutathione S transferase 0.0092 0.056 0.056
Brugia malayi Cytochrome P450 family protein 0.0043 0.0205 0.0303
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0176 0.1335
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0205 0.0922
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0205 0.0901
Loa Loa (eye worm) serotonin transporter b 0.009 0.0552 0.0818
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0205 0.0901
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0034 0.0051
Echinococcus multilocularis 0.0043 0.0205 0.0205
Loa Loa (eye worm) glutathione reductase 0.0047 0.024 0.0355
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0359 0.0532
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0267 0.0267
Leishmania major cytochrome p450-like protein 0.0078 0.0459 0.0851
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0176 0.0322
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Mycobacterium tuberculosis Conserved protein 0.0043 0.0211 0.0954
Leishmania major hypothetical protein, conserved 0.0021 0.0047 0.008
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0205 0.0922
Schistosoma mansoni hypothetical protein 0.008 0.0476 0.0476
Echinococcus granulosus acetylcholinesterase 0.0035 0.0149 0.0149
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.0047 0.0243
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0005 0.0005
Echinococcus granulosus expressed conserved protein 0.0094 0.058 0.058
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.0047 0.0243
Onchocerca volvulus 0.0015 0.0005 0.0015
Echinococcus multilocularis dna polymerase eta 0.0034 0.0146 0.0146
Brugia malayi ecdysteroid receptor 0.0237 0.1615 0.2392
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Brugia malayi laminin alpha chain 0.0095 0.0589 0.0872
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0032 0.0129 0.0129
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0075 0.0604
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0211 0.0313
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0146 0.0146
Echinococcus granulosus peroxidasin 0.0064 0.0359 0.0359
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0005 0.0007
Loa Loa (eye worm) FAD binding domain-containing protein 0.0054 0.0291 0.0431
Brugia malayi TAR-binding protein 0.0253 0.1733 0.2566
Onchocerca volvulus 0.0019 0.0034 0.0104
Leishmania major protein kinase, putative 0.003 0.0112 0.0201
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0102 0.031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0005 0.0007
Echinococcus multilocularis glutathione S transferase 0.0027 0.009 0.009
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0037 0.0296
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Echinococcus multilocularis ecdysone induced protein 78C 0.0237 0.1615 0.1615
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0267 0.0769
Leishmania major trypanothione reductase 0.0047 0.024 0.0441
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0237 0.1615 0.2392
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0022 0.0175
Mycobacterium tuberculosis Probable sulfatase 0.0017 0.0019 0.0041
Entamoeba histolytica rodhanase-like domain containing protein 0.0056 0.0306 0.2389
Onchocerca volvulus 0.0035 0.0149 0.0453
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0078 0.0465 0.0688
Echinococcus granulosus neuropeptide receptor 0.0015 0.0005 0.0005
Schistosoma mansoni NADPH flavin oxidoreductase 0.0027 0.0095 0.0095
Brugia malayi Latrophilin receptor protein 2 0.008 0.0476 0.0705
Giardia lamblia Serpin 1 0.0017 0.0018 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0005 0.0005
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0034 0.0051
Brugia malayi Nuclear hormone receptor E75 0.0112 0.0707 0.1047
Brugia malayi RE15519p 0.0015 0.0005 0.0007
Brugia malayi beta-lactamase 0.0043 0.0211 0.0313
Loa Loa (eye worm) hypothetical protein 0.0028 0.0102 0.0151
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.0118
Brugia malayi Uncoordinated protein 44 0.0014 0.00000002395 0.000000035461
Loa Loa (eye worm) hypothetical protein 0.0173 0.115 0.1702
Onchocerca volvulus 0.006 0.0328 0.0996
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Schistosoma mansoni hypothetical protein 0.002 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0128 0.0828 0.0828
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0211 0.0599
Loa Loa (eye worm) hypothetical protein 0.0081 0.0485 0.0718
Brugia malayi Sodium:neurotransmitter symporter family protein 0.009 0.0552 0.0818
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0205 0.0922
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0062 0.0446
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0129 0.0831 0.123
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0211 0.2122
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0207
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0075 0.0131
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0331 0.0331
Toxoplasma gondii protease inhibitor PI1 0.0017 0.0018 0.014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.068 0.3177
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.0102 0.0102
Onchocerca volvulus 0.0094 0.0577 0.1751
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.002
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0059 0.0343
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0054
Loa Loa (eye worm) hypothetical protein 0.0183 0.1223 0.1811
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0237 0.1615 0.2392
Echinococcus granulosus neurogenic locus notch protein 0.0095 0.0589 0.0589
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0237 0.1615 0.4902
Brugia malayi Cytochrome P450 family protein 0.0078 0.0459 0.0679
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Echinococcus granulosus GPCR family 2 0.008 0.0476 0.0476
Echinococcus granulosus Nuclear hormone receptor HR96 0.0112 0.0707 0.0707
Mycobacterium ulcerans sulfatase 0.0017 0.0019 0.0018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0237 0.1615 0.1615
Brugia malayi hypothetical protein 0.0323 0.2239 0.3316
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0007 0.0007
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0125 0.0804 0.1191
Schistosoma mansoni hypothetical protein 0.0029 0.0109 0.0109
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0598 0.1112
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0205 0.2026
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0384 0.2682 0.3971
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Onchocerca volvulus 0.0237 0.1615 0.4902
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0336 0.1542
Loa Loa (eye worm) hypothetical protein 0.0052 0.0274 0.0405
Echinococcus granulosus sex peptide receptor 0.0015 0.0005 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0112 0.0707 0.0707
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0034 0.0034
Schistosoma mansoni peroxidasin 0.0064 0.0359 0.0359
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0112 0.0707 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Leishmania major cytochrome p450-like protein 0.0043 0.0205 0.0375
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0476 0.0705
Brugia malayi hypothetical protein 0.0016 0.0011 0.0017
Onchocerca volvulus 0.0043 0.0211 0.0642
Loa Loa (eye worm) RNA binding protein 0.0253 0.1733 0.2566
Schistosoma mansoni ap endonuclease 0.0039 0.0176 0.0176
Trypanosoma brucei trypanothione reductase 0.0047 0.024 0.0441
Brugia malayi Cytochrome P450 family protein 0.0078 0.0459 0.0679
Brugia malayi G protein-coupled receptor 0.0015 0.0005 0.0007
Echinococcus granulosus microsomal glutathione S transferase 3 0.0109 0.0685 0.0685
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0376 0.0376
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0034 0.014 0.014
Echinococcus granulosus zinc finger protein 0.0021 0.0046 0.0046
Echinococcus granulosus voltage dependent calcium channel 0.0016 0.0015 0.0015
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.00000002395 0.00000002395
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0432 0.0639
Giardia lamblia DINP protein human, muc B family 0.0041 0.0195 0.1487
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0459 0.0851
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0474 0.3338 0.4942
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0077 0.0137
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.002
Onchocerca volvulus 0.0094 0.0577 0.1751
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0017 0.0022 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0267 0.0267
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0056 0.0306 0.0306
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0007 0.0007
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0137 0.0991
Trichomonas vaginalis set domain proteins, putative 0.0468 0.3294 1
Leishmania major hypothetical protein, conserved 0.0043 0.0211 0.0388
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0077 0.019
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.024 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Onchocerca volvulus Protein ultraspiracle homolog 0.0237 0.1615 0.4902
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0055
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0205 0.0901
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0034 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0021 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0267 0.0769
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0211 0.0933
Loa Loa (eye worm) hypothetical protein 0.0053 0.0279 0.0413
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0056 0.0306 0.0887
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0174 0.0174
Brugia malayi hypothetical protein 0.0017 0.0019 0.0028
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.2282
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0359 0.0532
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0005 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0343 0.1557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Giardia lamblia Synaptic glycoprotein SC2 0.0183 0.1223 1
Onchocerca volvulus 0.0468 0.3295 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0076 0.0449 0.0449
Loa Loa (eye worm) hypothetical protein 0.0094 0.0577 0.0854
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0432 0.0432
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0078 0.0465 0.0465
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0029 0.0109 0.0161
Echinococcus multilocularis slit 2 protein 0.0104 0.0649 0.0649
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.001
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0007 0.0007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0005 0.0005
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0068 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0211 0.0388
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0005
Brugia malayi ORL1-like opioid receptor 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0768 0.3593
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0077 0.019
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0245 0.0702
Loa Loa (eye worm) hypothetical protein 0.0945 0.6754 1
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0253 0.173 0.2561
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0077 0.0077
Echinococcus granulosus lamin 0.0081 0.0482 0.0482
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0017 0.0022 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0267 0.0769
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0336 0.0336
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0005 0.0005
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0149 0.0659
Loa Loa (eye worm) hypothetical protein 0.0039 0.0179 0.0265
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.024 0.1912
Brugia malayi Calcitonin receptor-like protein seb-1 0.0253 0.173 0.2561
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0211 0.0388
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0598 0.0598
Loa Loa (eye worm) nuclear receptor NHR-67 0.0112 0.0707 0.1047
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0205 0.0922
Echinococcus granulosus voltage dependent calcium channel 0.0078 0.0465 0.0465
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0048 0.0246 0.0705
Leishmania major DNA polymerase eta, putative 0.0034 0.0146 0.0265
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0094 0.0577 0.1751
Schistosoma mansoni thyroid hormone receptor 0.0365 0.2547 0.2547
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.0102 0.0102
Onchocerca volvulus 0.0019 0.0034 0.0104
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0294 0.0542
Echinococcus granulosus glutathione S transferase 0.0021 0.0046 0.0046
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0005 0.0005
Brugia malayi Blistered cuticle protein 3 0.0064 0.0359 0.0532
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0311 0.0575
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.001 0.0024
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0056 0.0306 0.0887
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0005 0.0005
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0034 0.0034
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0309 0.2135 0.2135
Brugia malayi Cation transporter family protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0095 0.0589 0.0872
Brugia malayi Nuclear hormone receptor E75 0.0112 0.0707 0.1047
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0211 0.0211
Schistosoma mansoni gabp alpha 0.0074 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni slit 0.0104 0.0649 0.0649
Brugia malayi sulfakinin receptor protein 0.0015 0.0005 0.0007
Echinococcus granulosus ecdysone induced protein 78C 0.0237 0.1615 0.1615
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Echinococcus granulosus serine protease inhibitor 0.0017 0.0018 0.0018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0211 0.0954
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0054 0.0291 0.0291
Schistosoma mansoni BC026374 protein (S09 family) 0.0035 0.0149 0.0149
Brugia malayi serpin 0.0017 0.0018 0.0026
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0034 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0205 0.0922
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0078 0.0459 0.2109
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0183 0.1223 0.3684
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0078 0.0465 0.0465
Entamoeba histolytica hypothetical protein 0.0183 0.1223 1
Brugia malayi nuclear receptor NHR-67 0.0112 0.0707 0.1047
Onchocerca volvulus 0.0043 0.0211 0.0642
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0005 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0078 0.0465 0.0465
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0183 0.1223 0.3684
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Brugia malayi hypothetical protein 0.0112 0.0707 0.1047
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0005
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0311 0.0311
Schistosoma mansoni hypothetical protein 0.0042 0.0197 0.0197
Echinococcus multilocularis thyroid hormone receptor alpha 0.0365 0.2547 0.2547
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0054 0.0291 0.0537
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0054
Echinococcus multilocularis para nitrobenzyl esterase 0.0035 0.0149 0.0149
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0237 0.1615 0.2392
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0109 0.0109
Leishmania major hypothetical protein, conserved 0.0025 0.0075 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0017 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0253 0.1733 0.1733
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0077 0.5288
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus thyroid hormone receptor alpha 0.0112 0.0707 0.0707
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0034 0.0034
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.021 0.0311
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Brugia malayi glutathione reductase 0.0047 0.024 0.0355
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0205 0.0922
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0034 0.0034
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0183 0.1223 0.1223
Echinococcus granulosus muscleblind protein 0.0152 0.1002 0.1002
Brugia malayi hypothetical protein 0.0064 0.0359 0.0532
Brugia malayi BmSERPIN 0.0017 0.0018 0.0026
Giardia lamblia Hypothetical protein 0.0017 0.0019 0.0031
Onchocerca volvulus 0.0017 0.0018 0.0054
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0062 0.0221
Brugia malayi Carboxylesterase family protein 0.0035 0.0149 0.0221
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0237 0.1615 0.1615
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0077 0.019
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0137 0.0249
Echinococcus granulosus tar DNA binding protein 0.0253 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.0037 0.0168 0.0249
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.0047 0.0098
Schistosoma mansoni hypothetical protein 0.0053 0.0279 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.017 0.0311
Brugia malayi hypothetical protein 0.0108 0.0678 0.1003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0598 0.0886
Brugia malayi Nuclear hormone receptor-like 1 0.0125 0.0804 0.1191
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0094 0.0577 0.0854
Brugia malayi Isocitrate dehydrogenase 0.0016 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Onchocerca volvulus 0.0015 0.0007 0.0022
Schistosoma mansoni agrin 0.0019 0.0037 0.0037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0193 0.1295 0.1917
Brugia malayi GnHR receptor homolog 0.0015 0.0005 0.0007
Trichomonas vaginalis cdc25c, putative 0.0056 0.0306 0.0887
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Echinococcus granulosus FTZ F1 alpha 0.0237 0.1615 0.1615
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0205 0.0922
Onchocerca volvulus 0.0028 0.0102 0.031
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0109 0.0685 0.0685
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Echinococcus multilocularis cpg binding protein 0.0032 0.0129 0.0129
Toxoplasma gondii exonuclease III APE 0.0039 0.0176 0.1437
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.002
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0625 0.0625
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0237 0.1615 0.2392
Trichomonas vaginalis spcc417.12 protein, putative 0.0035 0.0149 0.0409
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.1807 0.2676
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Echinococcus granulosus bloom syndrome protein 0.0042 0.0202 0.0202
Onchocerca volvulus 0.0025 0.0077 0.0235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0237 0.1615 0.1615
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0205 0.0901
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.1523
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0336 0.0336
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.068 0.8761
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 1
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.0102 0.0151
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0311 0.1408
Loa Loa (eye worm) serpin 0.0017 0.0018 0.0026
Plasmodium vivax glutathione reductase, putative 0.0047 0.024 0.1912
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0205 0.0922
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0359 0.109
Schistosoma mansoni hypothetical protein 0.0042 0.0197 0.0197
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0005 0.0005
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0176 0.1315
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0005 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0343 0.0633
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0048 0.0242 0.0445
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0037 0.0054
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0005 0.0005
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0184 0.1232 0.3739
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0034 0.0051
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0211 0.1679
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0062 0.2886
Schistosoma mansoni organic anion transporter 0.0028 0.0102 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0015 0.0005 0.0015
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0034 0.0034
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0062 0.0107
Schistosoma mansoni glutathione-S-transferase 0.0027 0.009 0.009
Onchocerca volvulus 0.0015 0.0005 0.0015
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0037 0.0054
Toxoplasma gondii hypothetical protein 0.0029 0.0109 0.0886
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0751 0.5347 1
Schistosoma mansoni nAChR subunit 0.0019 0.0034 0.0034
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0267 0.0492
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0075 0.0552
Trypanosoma brucei cytochrome P450, putative 0.0078 0.0459 0.0851
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0176 0.0492
Onchocerca volvulus 0.0019 0.0034 0.0104
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Brugia malayi hypoxia-induced factor 1 0.0298 0.2058 0.3047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.011
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0267 0.0492
Entamoeba histolytica hypothetical protein 0.0108 0.0678 0.5474
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0005
Brugia malayi Pre-SET motif family protein 0.0411 0.2882 0.4268
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0376 0.0696
Schistosoma mansoni tyrosinase precursor 0.0094 0.0577 0.0577
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0918 0.0918
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0183 0.1223 1
Brugia malayi ecdysone receptor 0.0112 0.0707 0.1047
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0112 0.0707 0.0707
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0359 0.0532
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Echinococcus multilocularis serotonin receptor 0.0015 0.0005 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0022 0.0175
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0237 0.1615 0.1615
Onchocerca volvulus 0.0015 0.0007 0.0022
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0598 0.0886
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0183 0.1223 0.1811
Schistosoma mansoni laminin gamma-3 chain 0.0104 0.0649 0.0649
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0205 0.0901
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0043 0.0205 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Treponema pallidum flavodoxin 0.0021 0.0047 0.0595
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0768 1
Brugia malayi hypothetical protein 0.0125 0.0804 0.1191
Echinococcus multilocularis glutathione s transferase mu 0.0027 0.009 0.009
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0109 0.0109
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0237 0.1615 0.1615
Schistosoma mansoni carbonic anhydrase 0.0029 0.0109 0.0109
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0594 0.0594
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0283 0.0419
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0146 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0112 0.0707 0.0707
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0077 0.0137
Loa Loa (eye worm) carboxylesterase 0.0035 0.0149 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.017 0.0311
Schistosoma mansoni kinase 0.0049 0.0255 0.0255
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0482 0.0713
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0019 0.0041
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis methionine synthase reductase 0.0034 0.014 0.014
Brugia malayi hypothetical protein 0.0017 0.0018 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0253 0.1733 0.1733
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0205 0.0901
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis voltage dependent calcium channel 0.0078 0.0465 0.0465
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0054 0.0291 0.0537
Onchocerca volvulus 0.0015 0.0005 0.0015
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0205 0.0901
Entamoeba histolytica hypothetical protein 0.0108 0.0678 0.5474
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0094 0.0577 0.0854
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.021 0.0311
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0079
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0598 0.1816
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0311 0.0461
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0007 0.0007
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0022
Echinococcus granulosus prostaglandin H2 D isomerase 0.0118 0.0755 0.0755
Onchocerca volvulus 0.0081 0.0482 0.1462
Brugia malayi G-protein coupled receptor 0.0015 0.0005 0.0007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0237 0.1615 0.1615
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus synaptic glycoprotein sc2 0.0183 0.1223 0.1223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0183 0.1223 0.1223
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0211 0.0954
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0237 0.1615 0.2392
Mycobacterium tuberculosis Conserved protein 0.0043 0.0211 0.0954
Loa Loa (eye worm) hypothetical protein 0.0079 0.0471 0.0698
Echinococcus multilocularis acetylcholinesterase 0.0035 0.0149 0.0149
Trypanosoma brucei C-8 sterol isomerase, putative 0.0751 0.5347 1
Mycobacterium ulcerans beta-lactamase 0.0043 0.0211 0.0933
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0183 0.1223 0.1223
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0076 0.0449 0.0665
Toxoplasma gondii hypothetical protein 0.0015 0.0007 0.0055
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0062 0.0866
Brugia malayi nuclear hormone receptor 0.0237 0.1615 0.2392
Echinococcus multilocularis geminin 0.1185 0.8494 0.8494
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0205 0.0901
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0034 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0253 0.173 0.2561
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0211 0.0954
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0751 0.5347 0.7916
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Echinococcus granulosus Estrogen regulated protein EP45 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Loa Loa (eye worm) hypothetical protein 0.0183 0.1223 0.1811
Toxoplasma gondii flavodoxin domain-containing protein 0.0027 0.0092 0.0747
Echinococcus multilocularis agrin 0.0019 0.0037 0.0037
Echinococcus granulosus dna polymerase eta 0.0034 0.0146 0.0146
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0013 0.0013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0034 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.1223 0.3684
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0432 0.0432
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0429 0.0429
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.3684
Echinococcus multilocularis serine protease inhibitor 0.0017 0.0018 0.0018
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0311 0.0311
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0005 0.0005
Brugia malayi Dopamine receptor protein 2 0.0015 0.0005 0.0007
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0129 0.0831 0.0831
Schistosoma mansoni lamin 0.0081 0.0482 0.0482
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0005 0.0007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0176 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0005 0.0005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.024 0.1088
Echinococcus multilocularis FTZ F1 alpha 0.0237 0.1615 0.1615
Loa Loa (eye worm) TAR-binding protein 0.0253 0.1733 0.2566
Loa Loa (eye worm) cytochrome P450 family protein 0.008 0.0478 0.0708
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0117 0.0211
Echinococcus granulosus carbonic anhydrase 0.0029 0.0109 0.0109
Schistosoma mansoni DNA helicase recq5 0.0017 0.0022 0.0022
Echinococcus multilocularis expressed conserved protein 0.0094 0.058 0.058
Brugia malayi photoreceptor-specific nuclear receptor 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Schistosoma mansoni ets-related 0.0224 0.1523 0.1523
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0054 0.0291 0.0291
Mycobacterium ulcerans hypothetical protein 0.0183 0.1223 0.5742
Brugia malayi Bromodomain containing protein 0.0075 0.0439 0.065
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0076 0.0449 0.0449
Echinococcus granulosus dnaJ subfamily B 0.0408 0.2857 0.2857
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.0047 0.0243
Mycobacterium leprae Possible regulatory protein 0.0025 0.0077 0.0224
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0323 0.2239 0.3316
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0459 0.0679
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0359 0.109
Loa Loa (eye worm) hypothetical protein 0.0052 0.0274 0.0405
Onchocerca volvulus 0.0193 0.1295 0.3929
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0205 0.0922
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.068 0.3177
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0205 0.0922
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0336 0.0336
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0102 0.0151
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0211 0.0211
Chlamydia trachomatis sulfite reductase 0.0034 0.014 1
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0768 0.3593
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0678 0.0678
Loa Loa (eye worm) hypothetical protein 0.0063 0.0354 0.0524
Loa Loa (eye worm) hypothetical protein 0.0125 0.0804 0.1191
Schistosoma mansoni microtubule-associated protein tau 0.1392 1 1
Echinococcus multilocularis muscleblind protein 1 0.0152 0.1002 0.1002
Loa Loa (eye worm) hypothetical protein 0.009 0.0552 0.0818
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0054 0.0291 0.0537
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Plasmodium falciparum nitric oxide synthase, putative 0.0054 0.0291 0.2333
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0195 0.0874
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0625 0.0625
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus granulosus methionine synthase reductase 0.0034 0.014 0.014
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0149 0.0659
Echinococcus granulosus glutathione s transferase mu 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0751 0.5347 0.7916
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0078 0.0465 0.0465
Onchocerca volvulus 0.0056 0.0306 0.0928
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0054 0.0291 0.0537
Schistosoma mansoni hypothetical protein 0.0193 0.1295 0.1295
Loa Loa (eye worm) abnormal epIthelia family member 0.0095 0.0589 0.0872
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0004
Echinococcus multilocularis sodium channel protein 0.0033 0.0137 0.0137
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0005
Schistosoma mansoni zinc finger protein 0.0112 0.0707 0.0707
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0015 0.0023
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.001 0.0024
Echinococcus multilocularis glutathione S transferase 0.0021 0.0046 0.0046
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0005 0.0005
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0037 0.0054
Brugia malayi neuropeptide F receptor 0.0015 0.0005 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0007 0.0007
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0007 0.0007
Schistosoma mansoni nuclear receptor 0.0112 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0015 0.0005 0.0015
Onchocerca volvulus 0.0056 0.0306 0.0928
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.0102 0.0102
Onchocerca volvulus 0.0056 0.0306 0.0928
Brugia malayi RNA binding protein 0.0253 0.1733 0.2566
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0026
Schistosoma mansoni serpin 0.0017 0.0018 0.0018
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0034 0.0034
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0583
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0017 0.0019 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0918 0.0918
Echinococcus multilocularis serine protease inhibitor 0.0017 0.0018 0.0018
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0017 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Brugia malayi Bromodomain containing protein 0.0037 0.0167 0.0248
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0176 0.0322
Trypanosoma brucei unspecified product 0.0055 0.0294 0.0542
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.1218 0.3667
Onchocerca volvulus 0.0064 0.0359 0.109
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Loa Loa (eye worm) ShTK domain-containing protein 0.0094 0.0577 0.0854
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0205 0.0901
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0311 0.1427
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0918 0.1359
Giardia lamblia Nitric oxide synthase, inducible 0.0048 0.0246 0.1913
Trypanosoma brucei polo-like protein kinase 0.0097 0.0598 0.1112
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0005 0.0005
Giardia lamblia Hypothetical protein 0.0048 0.0246 0.1913
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0005 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0146 0.0216
Echinococcus granulosus glutathione S transferase 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Brugia malayi Cation transporter family protein 0.0019 0.0034 0.0051
Onchocerca volvulus 0.0017 0.0018 0.0054
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0059 0.0135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0078 0.0465 0.0465
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0137 0.0249
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0021 0.0047 0.008
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0021 0.0047 0.008
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0062 0.0498
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0117 0.0211
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0108 0.0678 0.0678
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0678 0.0678
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0102 0.031
Brugia malayi laminin-like protein K08C7.3 precursor 0.0095 0.0589 0.0872
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0306 0.0453
Schistosoma mansoni peroxidasin 0.0064 0.0359 0.0359
Brugia malayi nuclear receptor RXR 0.0112 0.0707 0.1047
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.1523
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.0112 0.0707 0.1047
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0205 0.0901
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1807 0.5466
Echinococcus multilocularis tar DNA binding protein 0.0253 0.1733 0.1733
Brugia malayi nuclear hormone receptor family member nhr-6 0.0112 0.0707 0.1047
Leishmania major DNA polymerase kappa, putative 0.0041 0.0195 0.0356
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0237 0.1615 0.2392
Brugia malayi beta-lactamase family protein 0.0043 0.0211 0.0313
Trypanosoma brucei unspecified product 0.0024 0.0068 0.012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0221
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Leishmania major carbonic anhydrase-like protein 0.0129 0.0831 0.1547
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0125 0.0804 0.0804
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0056 0.0306 0.0887
Schistosoma mansoni microsomal glutathione s-transferase 0.0109 0.0685 0.0685
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0237 0.1615 0.1615
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.001
Schistosoma mansoni lamin 0.0081 0.0482 0.0482
Onchocerca volvulus 0.0017 0.0018 0.0054
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0021 0.0047 0.0327
Schistosoma mansoni blooms syndrome DNA helicase 0.0033 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0037 0.0168 0.0249
Trichomonas vaginalis cdc25b, putative 0.0056 0.0306 0.0887
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0037 0.0296
Echinococcus granulosus serotonin receptor 0.0015 0.0005 0.0005
Brugia malayi Synaptic glycoprotein SC2 0.0183 0.1223 0.1811
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Brugia malayi Common central domain of tyrosinase family protein 0.0094 0.0577 0.0854
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0267 0.2179
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0237 0.1615 0.2392
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0034 0.0051
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0037 0.0054
Loa Loa (eye worm) hypothetical protein 0.0027 0.009 0.0134
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Entamoeba histolytica hypothetical protein 0.0108 0.0678 0.5474
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0376 0.0557
Echinococcus granulosus Nuclear hormone receptor HR96 0.0112 0.0707 0.0707
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0005
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0112 0.0707 0.1047
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Brugia malayi Thioredoxin reductase 0.0047 0.024 0.0355
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.001 0.001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0059 0.0103
Echinococcus multilocularis glutathione S transferase 0.0027 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0005 0.0005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0125 0.0804 0.0804
Echinococcus multilocularis protein patched 0.0043 0.0209 0.0209
Plasmodium falciparum thioredoxin reductase 0.0016 0.0015 0.0064
Echinococcus granulosus orexin receptor type 2 0.0015 0.0005 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0176 0.3
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0118 0.0755 0.0755
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0054 0.0291 0.0291
Loa Loa (eye worm) norepinephrine transporter 0.009 0.0552 0.0818
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0054 0.0291 0.0537
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0054
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0195 0.0356
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.002
Giardia lamblia Kinase, PLK 0.0097 0.0598 0.4828
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0112 0.0707 0.2146
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0205 0.0375
Echinococcus multilocularis nAChR subunit 0.0019 0.0034 0.0034
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0054 0.0291 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.3684
Mycobacterium tuberculosis Conserved protein 0.0043 0.0211 0.0954
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0161
Treponema pallidum sodium- and chloride- dependent transporter 0.009 0.0552 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.1807 0.2676
Onchocerca volvulus 0.0015 0.0005 0.0015
Toxoplasma gondii flavodoxin domain-containing protein 0.0027 0.0092 0.0747
Plasmodium vivax polyprenol reductase, putative 0.0183 0.1223 1
Onchocerca volvulus 0.0017 0.0018 0.0054
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0376 0.0376
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0205 0.0922
Trypanosoma brucei protein kinase, putative 0.0051 0.0267 0.0492
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0237 0.1615 0.1615
Schistosoma mansoni GST class-mu 0.0027 0.009 0.009
Schistosoma mansoni gliotactin 0.0035 0.0149 0.0149
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0482 0.0713
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0051
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.008 0.0476 0.0476
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0019 0.0018
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0176 0.0176
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0474 0.3339 0.3339
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0918 0.1359
Loa Loa (eye worm) hypothetical protein 0.008 0.0476 0.0705
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0183 0.1223 0.2282
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0109 0.0161
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0007 0.0007
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0035 0.0149 0.0149
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0211 0.0954
Brugia malayi cytochrome P450 0.0043 0.0205 0.0303
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0918 0.0918
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0343 0.1557
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0267 0.0492
Schistosoma mansoni hypothetical protein 0.0042 0.0197 0.0197
Onchocerca volvulus Peroxidase homolog 0.0064 0.0359 0.109
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0005
Schistosoma mansoni DNA polymerase eta 0.0034 0.0146 0.0146
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0625 0.5034
Onchocerca volvulus 0.0015 0.0005 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus granulosus glutathione S transferase Mu 1 0.0027 0.009 0.009
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0146 0.0265
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0112 0.0707 0.0707
Echinococcus multilocularis expressed protein 0.0034 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0104 0.0649 0.0961
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0211 0.0599
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0034 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0237 0.1615 0.2392
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0176 0.0766
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0376 0.0696
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0083 0.0147
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0011
Echinococcus multilocularis glutathione S transferase 0.0021 0.0046 0.0046
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0828 0.0828
Loa Loa (eye worm) hypoxia-induced factor 1 0.0298 0.2058 0.3047
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0037 0.0296
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0078 0.0465 0.0465
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0077 0.0137
Loa Loa (eye worm) hypothetical protein 0.0043 0.0211 0.0313
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0083 0.0147
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0034 0.0051
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0343 0.0343
Loa Loa (eye worm) serpin 0.0017 0.0018 0.0026
Onchocerca volvulus 0.0043 0.0211 0.0642
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0019 0.0034 0.0104
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0237 0.1615 0.2392
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0146 0.0216
Schistosoma mansoni cell polarity protein 0.0095 0.0589 0.0589
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0007 0.0055
Loa Loa (eye worm) hypothetical protein 0.0081 0.0482 0.0713
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0007 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0205 0.0922
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.0047 0.0243
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0311 0.0311
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.1392 1 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.1002 0.1483
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0205 0.0901
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0034 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Plasmodium vivax flavodoxin domain containing protein 0.0048 0.0246 0.1964
Loa Loa (eye worm) hypothetical protein 0.0237 0.1615 0.2392
Loa Loa (eye worm) hypothetical protein 0.0064 0.0359 0.0532
Trichomonas vaginalis rotamase, putative 0.0033 0.0137 0.0373
Loa Loa (eye worm) DR-78 0.0112 0.0707 0.1047
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0005 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0482 0.0713
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0034 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0237 0.1615 0.2392
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0137 0.0249
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0205 0.0922
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0598 0.1779
Schistosoma mansoni serine protease inhibitors serpins 0.0017 0.0018 0.0018
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0109 0.0161
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0007 0.0007
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0359 0.0532
Schistosoma mansoni patched 1 0.0043 0.0209 0.0209
Schistosoma mansoni bromodomain containing protein 0.0063 0.0356 0.0356
Giardia lamblia Hypothetical protein 0.0017 0.0019 0.0031
Onchocerca volvulus 0.0112 0.0707 0.2146
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0025 0.0077 0.0115
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.009 0.0552 0.0818
Brugia malayi serpin 0.0017 0.0018 0.0026
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0937 0.0937
Onchocerca volvulus 0.0015 0.0005 0.0015
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0019 0.0041
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0007 0.0007
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0054 0.0291 0.2333
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.115 0.3461
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0267 0.0492
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0075 0.0552
Echinococcus multilocularis sex peptide receptor 0.0015 0.0005 0.0005
Echinococcus granulosus carboxylesterase 5A 0.0035 0.0149 0.0149
Brugia malayi hypothetical protein 0.0015 0.0005 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0211 0.0211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0205 0.0901
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0343 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0205 0.0922
Onchocerca volvulus Peroxidase homolog 0.0064 0.0359 0.109
Echinococcus multilocularis survival motor neuron protein 1 0.0945 0.6754 0.6754
Brugia malayi Protein kinase domain containing protein 0.0015 0.0006 0.0008
Echinococcus multilocularis serotonin transporter 0.009 0.0552 0.0552
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0005 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0211 0.0599
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0237 0.1615 0.1615
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0062 0.0446
Loa Loa (eye worm) hypothetical protein 0.0112 0.0707 0.1047
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0237 0.1615 0.2392
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0359 0.0532
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0476 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0019 0.0012
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0183 0.1223 0.3684
Brugia malayi BmSERPIN, truncated 0.0017 0.0018 0.0026
Brugia malayi serpin (BmSERPIN) 0.0017 0.0018 0.0026
Brugia malayi Pre-SET motif family protein 0.006 0.0328 0.0486
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.0035 0.0149 0.0221
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0129 0.0831 0.123
Brugia malayi hypothetical protein 0.0035 0.0149 0.0221
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0056 0.0306 0.0887
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0918 0.0918
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Brugia malayi Dopamine receptor 0.0015 0.0005 0.0007
Echinococcus granulosus dna polymerase kappa 0.0062 0.0343 0.0343
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0237 0.1615 0.1615
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0112 0.0707 0.0707
Echinococcus multilocularis lamin 0.0081 0.0482 0.0482
Schistosoma mansoni nuclear hormone receptor 0.0237 0.1615 0.1615
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0211 0.0388
Schistosoma mansoni acetylcholinesterase 0.0035 0.0149 0.0149
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.001 0.0015

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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