Detailed information for compound 1239424

Basic information

Technical information
  • TDR Targets ID: 1239424
  • Name: (1R)-1-[(3aS,5R,6R,6aS)-6-(3-dimethylaminopro poxy)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[4 ,5-d][1,3]dioxol-5-yl]ethane-1,2-diol
  • MW: 305.367 | Formula: C14H27NO6
  • H donors: 2 H acceptors: 2 LogP: -0.65 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]([C@H]1O[C@@H]2[C@H]([C@@H]1OCCCN(C)C)OC(O2)(C)C)O
  • InChi: 1S/C14H27NO6/c1-14(2)20-12-11(18-7-5-6-15(3)4)10(9(17)8-16)19-13(12)21-14/h9-13,16-17H,5-8H2,1-4H3/t9-,10-,11-,12+,13+/m1/s1
  • InChiKey: YXBQLONCIPUQKO-KVSVUVNWSA-N  

Network

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Synonyms

  • NCGC00016894-01
  • CAS-60414-06-4

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0002 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0066 0.0697
Plasmodium vivax vivapain-2 0.0019 0.0002 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0029 0.0029
Schistosoma mansoni glutaminase 0.0264 0.0297 0.0837
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0046 0.0035 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0522 0.0606 0.2917
Leishmania major hypothetical protein, conserved 0.0522 0.0606 0.6522
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0091 0.0089 0.0223
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0019 0.0082
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.004 0.0028 0.0276
Echinococcus granulosus lysosomal alpha glucosidase 0.069 0.0807 0.2274
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0029 0.0285
Brugia malayi Carboxylesterase family protein 0.0023 0.0008 0.0056
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Echinococcus granulosus tumor protein p63 0.1011 0.1192 0.3362
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.0036 0.0036
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0116 0.0119 0.0788
Mycobacterium leprae Polyketide synthase Pks13 0.0075 0.0069 0.0788
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0007 0.0021
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0008 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0033 0.0019 0.0188
Loa Loa (eye worm) hypothetical protein 0.0153 0.0163 0.1084
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0116 0.0119 0.1263
Brugia malayi 6-phosphofructokinase 0.0131 0.0137 0.0978
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0157 0.0168 0.1113
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0037 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0606 0.0706 0.1992
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0084 0.0081 0.0228
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.004 0.0396
Toxoplasma gondii NADPH-glutathione reductase 0.0063 0.0055 0.0164
Echinococcus granulosus smad 0.0051 0.004 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0041 0.0188
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0023 0.0008 0.0064
Echinococcus granulosus acetylcholinesterase 0.0139 0.0146 0.0413
Onchocerca volvulus 0.0019 0.0002 0.0017
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Plasmodium falciparum pyruvate kinase 0.0034 0.002 0.0059
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0022 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0055 0.0156
Giardia lamblia GTOR 0.0018 0.0002 0.0004
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0076 0.007 0.007
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0323 0.0367 0.1096
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0157 0.1122
Giardia lamblia PHD finger protein 15 0.0123 0.0128 0.038
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Trypanosoma cruzi hexose transporter 0.0034 0.002 0.0198
Trichomonas vaginalis ap endonuclease, putative 0.0116 0.0119 0.0565
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0091 0.0089 0.1016
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0026 0.0011 0.0078
Echinococcus granulosus PHD finger protein rhinoceros 0.0123 0.0128 0.036
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0008 0.0022
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0007 0.0021
Brugia malayi AF-10 protein 0.004 0.0028 0.02
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Toxoplasma gondii thioredoxin reductase 0.0182 0.0198 0.0591
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0172
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0023 0.0008 0.0082
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.0027 0.0027
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0029 0.0014 0.0157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0022 0.0144
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0096 0.0095 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Leishmania major 4-coumarate:coa ligase-like protein 0.0141 0.0148 0.1582
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0008 0.0019
Loa Loa (eye worm) thioredoxin reductase 0.0182 0.0198 0.1316
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0033 0.0219
Brugia malayi PHD-finger family protein 0.0123 0.0128 0.091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0084 0.0081 0.0535
Echinococcus granulosus neuroligin 0.0023 0.0008 0.0022
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0002 0.0017
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0091 0.0089 0.094
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0153 0.0163 0.1743
Loa Loa (eye worm) carboxylesterase 0.0023 0.0008 0.0052
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Trypanosoma brucei unspecified product 0.0041 0.0029 0.029
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0007 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0015 0.0062
Trypanosoma cruzi FHA domain containing protein, putative 0.0029 0.0014 0.0137
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 0.0832
Echinococcus multilocularis protein patched 0.0125 0.013 0.013
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0157 0.0443
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0083 0.0552
Toxoplasma gondii PHD-finger domain-containing protein 0.0123 0.0128 0.038
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0026 0.0011 0.0072
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0028 0.0081
Loa Loa (eye worm) hypothetical protein 0.0062 0.0054 0.036
Entamoeba histolytica hypothetical protein 0.0025 0.001 0.0111
Giardia lamblia DINP protein human, muc B family 0.0041 0.0029 0.0084
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0009 0.0025
Echinococcus multilocularis RUN 0.0041 0.0029 0.0029
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0063 0.0055 0.0579
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Brugia malayi hypothetical protein 0.0029 0.0014 0.0103
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0082 0.0231
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0084 0.0081 0.0228
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0163 0.0779
Echinococcus multilocularis musashi 0.0083 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0404 0.0464 0.308
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0091 0.0089 0.0264
Giardia lamblia Kinase, CMGC MAPK 0.0157 0.0168 0.05
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0096 0.0095 0.0238
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0038 0.0025 0.0073
Brugia malayi PHD-finger family protein 0.0045 0.0034 0.0242
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1068 0.126 0.3764
Schistosoma mansoni phd/f-box containing protein 0.004 0.0027 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Toxoplasma gondii type I fatty acid synthase, putative 0.0066 0.0058 0.0173
Brugia malayi jmjC domain containing protein 0.004 0.0027 0.0196
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0323 0.0367 0.0922
Mycobacterium tuberculosis Conserved protein 0.0522 0.0606 0.1522
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0128 0.038
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0022 0.1831
Brugia malayi mbt repeat family protein 0.0046 0.0035 0.0249
Echinococcus multilocularis peregrin 0.0127 0.0132 0.0132
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0067 0.006 0.006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0081 0.0228
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0081 0.0576
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.005 0.004 0.0099
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0025 0.0247
Brugia malayi Carboxylesterase family protein 0.0023 0.0008 0.0056
Echinococcus multilocularis expressed conserved protein 0.0274 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0141 0.0148 0.0984
Echinococcus multilocularis carboxylesterase 5A 0.0139 0.0146 0.0146
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0002 0.0013
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0091 0.0089 0.0223
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0022 0.0065
Loa Loa (eye worm) pyruvate kinase 0.0034 0.002 0.0135
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0029 0.0014 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.0019 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Brugia malayi hypothetical protein 0.0029 0.0014 0.0103
Trypanosoma cruzi hexose transporter, putative 0.0034 0.002 0.0198
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0022 0.0063
Echinococcus granulosus histone lysine methyltransferase setb 0.0098 0.0097 0.0274
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0063 0.0055 0.056
Loa Loa (eye worm) hypothetical protein 0.0141 0.0148 0.0984
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.2809 0.3348 0.9441
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0091 0.0089 0.025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0063 0.0055 0.0579
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0029 0.0081
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0026 0.0011 0.0031
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0026 0.0011 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.0027 0.008
Echinococcus multilocularis cysteine protease 0.0019 0.0002 0.0002
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0008 0.0029
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0462 0.0534 0.1342
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0082 0.0231
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0098
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0008 0.0022
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0095 0.0964
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0027 0.0195
Echinococcus multilocularis smad 0.0051 0.004 0.004
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0091 0.0089 0.0223
Brugia malayi Patched related family protein 12 0.0018 0.0001 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0099 0.0279
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0055 0.0394
Onchocerca volvulus 0.0522 0.0606 0.6758
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0116 0.0119 0.1263
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0002 0.0006
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0028 0.032
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0081 0.0228
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0022
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0027 0.0181
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0037 0.0105
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Leishmania major pyruvate kinase 0.0034 0.002 0.0199
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0009 0.0091
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0141 0.0148 0.1703
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Echinococcus multilocularis expressed protein 0.0451 0.052 0.052
Schistosoma mansoni high-affinity choline transporter 0.0076 0.007 0.0198
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0137 0.1461
Echinococcus multilocularis pyruvate kinase 0.0027 0.0012 0.0012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0034
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0183 0.0199 0.0561
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.011 0.0523
Echinococcus granulosus Niemann Pick C1 protein 0.0417 0.0479 0.1351
Echinococcus granulosus chromobox protein 1 0.0073 0.0068 0.0191
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.005 0.004 0.0099
Echinococcus multilocularis AMP dependent ligase 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0026 0.0011 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0033 0.015
Loa Loa (eye worm) ctsf protein 0.0019 0.0002 0.0016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0712 0.0833 0.2349
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0032 0.0018 0.0054
Toxoplasma gondii HEAT repeat-containing protein 0.0119 0.0123 0.0365
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.0079
Echinococcus granulosus General substrate transporter 0.0094 0.0092 0.0259
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0124 0.1259
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0014 0.0137
Plasmodium vivax patched family protein, putative 0.0018 0.0001 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0029 0.0291
Onchocerca volvulus 0.0522 0.0606 0.6758
Schistosoma mansoni GTP-binding protein alpha subunit 0.0026 0.0011 0.0031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0063 0.0055 0.3929
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0193
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0007 0.0021
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0025 0.0254
Echinococcus multilocularis ecdysone induced protein 78C 0.0084 0.0081 0.0081
Mycobacterium ulcerans polyketide synthase Pks13 0.0075 0.0069 0.07
Loa Loa (eye worm) hypothetical protein 0.1186 0.1402 0.9301
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0098
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0022 0.0063
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0137 0.1636
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0081 0.0576
Echinococcus multilocularis importin subunit beta 1 0.0119 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Echinococcus granulosus traf and tnf receptor associated protein 0.0023 0.0008 0.0022
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0007 0.0007
Schistosoma mansoni pyruvate kinase 0.0034 0.002 0.0057
Brugia malayi Pre-SET motif family protein 0.0098 0.0097 0.0693
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0482 0.0558 0.0558
Mycobacterium tuberculosis Probable exported protein 0.0023 0.0008 0.0019
Brugia malayi MH1 domain containing protein 0.0051 0.004 0.0288
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0007 0.0007
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0153 0.0163 0.0779
Schistosoma mansoni FFA transport protein 0.0752 0.0882 0.2486
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0178 0.0193 0.0574
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0023 0.0008 0.0064
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Echinococcus granulosus serine protein kinase ATM 0.0025 0.001 0.0028
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.0545 0.0545
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.012 0.0124 0.0349
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Mycobacterium leprae Probable polyketide synthase Pks1 0.0053 0.0043 0.0489
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0082 0.0936
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0022 0.0063
Schistosoma mansoni kinase 0.0052 0.0042 0.0119
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.002 0.0198
Onchocerca volvulus 0.0141 0.0148 0.1647
Brugia malayi Patched protein homolog 1 0.0018 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0712 0.0833 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0019 0.0125
Brugia malayi isocitrate dehydrogenase 0.0048 0.0037 0.0265
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0098
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0002 0.0006
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0037 0.0105
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0002 0.0012
Echinococcus multilocularis pyruvate kinase 0.0034 0.002 0.002
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0109 0.011 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0168 0.0802
Leishmania major pantothenate kinase subunit, putative 0.0036 0.0023 0.0228
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0027 0.0182
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0063 0.0055 0.0139
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0084 0.0081 0.0535
Loa Loa (eye worm) hypothetical protein 0.0034 0.002 0.0135
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0033 0.0093
Onchocerca volvulus 0.0023 0.0008 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0068 0.0319
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0008 0.0029
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0051
Loa Loa (eye worm) glutaminase 0.0264 0.0297 0.1969
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0096 0.0454
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0055 0.0367
Loa Loa (eye worm) hypothetical protein 0.0098 0.0097 0.0644
Trichomonas vaginalis importin beta-1, putative 0.0097 0.0096 0.0454
Echinococcus multilocularis neutral alpha glucosidase AB 0.0153 0.0163 0.0163
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0027 0.0027
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0023 0.0008 0.0064
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0037 0.0037
Toxoplasma gondii cathepsin CPC1 0.2809 0.3348 1
Trypanosoma cruzi hypothetical protein, conserved 0.0522 0.0606 0.6522
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Echinococcus granulosus GTP binding nuclear protein Ran 0.0067 0.006 0.017
Echinococcus granulosus neutral alpha glucosidase AB 0.0153 0.0163 0.046
Schistosoma mansoni glucose transport protein 0.0109 0.011 0.0311
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0752 0.0882 0.9503
Entamoeba histolytica cysteine protease, putative 0.0019 0.0002 0.0018
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0008 0.0064
Echinococcus granulosus GPCR family 2 0.0326 0.037 0.1044
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0029 0.013
Schistosoma mansoni chromobox protein 0.0073 0.0068 0.0191
Loa Loa (eye worm) hypothetical protein 0.0139 0.0146 0.0971
Loa Loa (eye worm) hypothetical protein 0.0032 0.0018 0.0122
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0006 0.0044
Mycobacterium ulcerans acetyl-CoA synthetase 0.0091 0.0089 0.0902
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Mycobacterium ulcerans polyketide synthase 0.0053 0.0043 0.0434
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0035 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0091 0.0089 0.0223
Schistosoma mansoni hypothetical protein 0.0109 0.011 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Leishmania major fatty acid transporter protein-like protein 0.074 0.0867 0.9339
Trichomonas vaginalis sugar transporter, putative 0.0034 0.002 0.0088
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0023 0.0008 0.0064
Mycobacterium tuberculosis Probable dehydrogenase 0.0416 0.0478 0.1202
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0008 0.0029
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0029 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0137 0.0909
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0153 0.0163 0.0779
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0141 0.0148 0.1512
Echinococcus granulosus phd:f box containing protein 0.004 0.0027 0.0077
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0116 0.0119 0.0353
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0067 0.006 0.0179
Chlamydia trachomatis pyruvate kinase 0.0034 0.002 0.157
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0025 0.0973
Plasmodium vivax SET domain protein, putative 0.0098 0.0097 0.0289
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0023 0.0008 0.0064
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.005 0.004 0.0446
Schistosoma mansoni hypothetical protein 0.0123 0.0128 0.036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0008 0.0022
Loa Loa (eye worm) transcription factor SMAD2 0.0743 0.0871 0.5779
Onchocerca volvulus 0.0046 0.0035 0.038
Echinococcus granulosus microtubule associated protein 2 0.2975 0.3547 1
Schistosoma mansoni hypothetical protein 0.0304 0.0344 0.0969
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.103 0.1214 0.866
Brugia malayi jmjC domain containing protein 0.004 0.0027 0.0196
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0032 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0153 0.0163 0.1743
Brugia malayi G-protein alpha subunit 0.0026 0.0011 0.0078
Schistosoma mansoni pyruvate kinase 0.0017 0.0001 0.0001
Trichomonas vaginalis glutaminase, putative 0.0264 0.0297 0.1425
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0029 0.0014 0.0139
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0168 0.1793
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0791 0.0928 0.6617
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0019 0.0053
Toxoplasma gondii PHD-finger domain-containing protein 0.0123 0.0128 0.038
Toxoplasma gondii preprocathepsin c precursor, putative 0.2809 0.3348 1
Brugia malayi PXA domain containing protein 0.0023 0.0007 0.0053
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.0027 0.0027
Schistosoma mansoni transcription factor LCR-F1 0.0712 0.0833 0.2349
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Loa Loa (eye worm) hypothetical protein 0.0091 0.0089 0.0589
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0082 0.0078 0.0514
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0007 0.0007
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0137 0.1397
Brugia malayi exodeoxyribonuclease III family protein 0.0116 0.0119 0.0847
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0028 0.0283
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0029 0.0081
Trypanosoma cruzi hexose transporter, putative 0.0034 0.002 0.0198
Toxoplasma gondii exonuclease III APE 0.0116 0.0119 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Loa Loa (eye worm) hypothetical protein 0.0045 0.0033 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Echinococcus granulosus dna polymerase kappa 0.0041 0.0029 0.0081
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0045
Loa Loa (eye worm) hypothetical protein 0.0134 0.0141 0.0934
Schistosoma mansoni ap endonuclease 0.0116 0.0119 0.0335
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0027 0.0277
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0137 0.0653
Onchocerca volvulus 0.0083 0.0079 0.0877
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Brugia malayi AMP-binding enzyme family protein 0.0091 0.0089 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0416 0.0478 0.1202
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0002 0.0018
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0791 0.0928 1
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0048 0.0497
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0022 0.0065
Plasmodium falciparum thioredoxin reductase 0.0182 0.0198 0.0591
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0026 0.0011 0.0031
Mycobacterium tuberculosis Conserved protein 0.0522 0.0606 0.1522
Schistosoma mansoni glucose transport protein 0.0109 0.011 0.0311
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0205 0.0225 0.0225
Trichomonas vaginalis Phospholipase C precursor, putative 0.0023 0.0008 0.0029
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0008 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0076 0.007 0.007
Echinococcus multilocularis neuroligin 0.0023 0.0008 0.0008
Onchocerca volvulus 0.0019 0.0002 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Mycobacterium ulcerans beta-lactamase 0.0522 0.0606 0.6204
Brugia malayi Thioredoxin reductase 0.0182 0.0198 0.1415
Loa Loa (eye worm) patched family protein 0.0018 0.0001 0.0006
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0026 0.0011 0.0078
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0082 0.0243
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0028 0.0078
Trichomonas vaginalis maltase-glucoamylase, putative 0.0153 0.0163 0.0779
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0522 0.0606 0.432
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Onchocerca volvulus 0.0023 0.0008 0.0078
Trypanosoma brucei glucose transporter 1E 0.0034 0.002 0.0198
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.001 0.001
Onchocerca volvulus 0.011 0.0112 0.1236
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0053 0.0043 0.0489
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.002 0.0217
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0025 0.0254
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0046 0.0035 0.0252
Mycobacterium tuberculosis Probable hydrolase 0.0522 0.0606 0.1522
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.011 0.011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0007 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0606 0.0706 0.1992
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0141 0.0148 0.0372
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.002 0.0198
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0079 0.0526
Echinococcus multilocularis muscleblind protein 1 0.0904 0.1063 0.1063
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0063 0.0055 0.3929
Onchocerca volvulus 0.0041 0.0029 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0084 0.0081 0.0576
Loa Loa (eye worm) acyl carrier protein 0.0023 0.0007 0.0048
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0124 0.0124
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0026 0.0011 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0029 0.0291
Schistosoma mansoni ap endonuclease 0.0116 0.0119 0.0335
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0048 0.0223
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0029 0.0072
Trypanosoma cruzi lanosterol synthase, putative 0.0212 0.0234 0.2503
Schistosoma mansoni acetyl-CoA synthetase 0.0091 0.0089 0.025
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0026 0.0011 0.0044
Echinococcus granulosus solute carrier family 5 0.0076 0.007 0.0198
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0009 0.0025
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0099 0.0279
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0026 0.0011 0.0078
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0048 0.0499
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0008 0.0008
Schistosoma mansoni inositol transporter 0.0076 0.007 0.0198
Mycobacterium tuberculosis Probable lipase LipE 0.0522 0.0606 0.1522
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0205 0.0225 0.0636
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0292 0.0329 0.3946
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0152 0.0429
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.0033 0.0033
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0025 0.0243
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0032 0.009
Brugia malayi hypothetical protein 0.0139 0.0146 0.1042
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0063 0.0055 0.0579
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.0398 0.4767
Trichomonas vaginalis ap endonuclease, putative 0.0116 0.0119 0.0565
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0007 0.0021
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0482 0.0558 0.1574
Entamoeba histolytica hypothetical protein 0.0712 0.0833 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0116 0.0119 0.0335
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0026 0.0011 0.0031
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0037 0.0109
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.002 0.0145
Brugia malayi hypothetical protein 0.0023 0.0008 0.0056
Brugia malayi Carboxylesterase family protein 0.0023 0.0008 0.0056
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0022 0.0065
Mycobacterium ulcerans thioesterase TesA 0.0042 0.003 0.0294
Treponema pallidum DNA ligase (lig) 0.0029 0.0014 0.0172
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0137 0.0386
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0015 0.0184
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.0027 0.0277
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0097 0.0097
Onchocerca volvulus 0.0019 0.0002 0.0017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0522 0.0606 0.1522
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.011 0.011
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0124 0.1259
Treponema pallidum hypothetical protein 0.0323 0.0367 0.9223
Leishmania major cathepsin L-like protease 0.0072 0.0066 0.0697
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0139 0.0146 0.0969
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0063 0.0055 0.0579
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0116 0.0119 0.0353
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0008 0.0022
Leishmania major hypothetical protein, conserved 0.0104 0.0104 0.1108
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0001 0.0002
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0084 0.0081 0.0576
Echinococcus multilocularis lysine specific demethylase 5A 0.0149 0.0159 0.0159
Trichomonas vaginalis hypothetical protein 0.0023 0.0007 0.0024
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0037 0.0382
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0027 0.0182
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0007 0.0021
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.002 0.0199
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0672 0.0785 0.5207
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Leishmania major alpha glucosidase II subunit, putative 0.0153 0.0163 0.1742
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0063 0.0055 0.0164
Giardia lamblia Dipeptidyl-peptidase I precursor 0.2809 0.3348 1
Onchocerca volvulus 0.0023 0.0008 0.0077
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0029 0.0014 0.0163
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0002 0.0002
Giardia lamblia Inositol 5-phosphatase 4 0.0023 0.0008 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Plasmodium falciparum protein kinase 6 0.0464 0.0536 0.1598
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0027 0.0181
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0606 0.0706 0.1992
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0022 0.0065
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0027 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0163 0.0779
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0009 0.0063
Echinococcus multilocularis pyruvate kinase 0.0034 0.002 0.002
Trichomonas vaginalis esterase, putative 0.0522 0.0606 0.2917
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0606 0.0706 0.5039
Brugia malayi AMP-binding enzyme family protein 0.0831 0.0976 0.6959
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0191
Brugia malayi Patched related family protein 4 0.0018 0.0001 0.0006
Brugia malayi GH02984p 0.0076 0.007 0.0501
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0008 0.0022
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Onchocerca volvulus 0.0023 0.0008 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0027 0.0027
Schistosoma mansoni smad1 5 8 and 0.0051 0.004 0.0114
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 0.0832
Leishmania major lanosterol synthase, putative 0.0212 0.0234 0.2502
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0029 0.0291
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0035 0.0098
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0007 0.0021
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0022 0.0063
Brugia malayi MH1 domain containing protein 0.0051 0.004 0.0288
Echinococcus granulosus pyruvate kinase 0.0034 0.002 0.0057
Brugia malayi RNA, U transporter 1 0.0339 0.0387 0.2758
Schistosoma mansoni jumonji/arid domain-containing protein 0.0154 0.0165 0.0464
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0042 0.003 0.0331
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0011 0.0074
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0416 0.0478 0.1202
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0096 0.0095 0.1086
Schistosoma mansoni synaptojanin 0.0023 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0091 0.0089 0.0634
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0076 0.007 0.0198
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0084 0.0081 0.0535
Echinococcus multilocularis solute carrier family 5 0.0076 0.007 0.007
Brugia malayi F/Y-rich N-terminus family protein 0.007 0.0064 0.0456
Echinococcus granulosus beta LACTamase domain containing family member 0.0522 0.0606 0.1708
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0163 0.0779
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0007 0.0007
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0144
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0022 0.0063
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.0027 0.0077
Trichomonas vaginalis glucose transporter, putative 0.0034 0.002 0.0088
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0023 0.0008 0.0029
Loa Loa (eye worm) patched family protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0037 0.0247
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0088
Echinococcus granulosus importin 5 0.0023 0.0007 0.0019
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0023 0.0007 0.0053
Schistosoma mansoni hypothetical protein 0.0121 0.0124 0.035
Echinococcus multilocularis lysosomal alpha glucosidase 0.069 0.0807 0.0807
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0091 0.0089 0.0634
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.0027 0.0077
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0063 0.0055 0.0164
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0255 0.0285 0.1892
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0137 0.1636
Brugia malayi Sodium:solute symporter family protein 0.0076 0.007 0.0501
Brugia malayi nuclear hormone receptor 0.0084 0.0081 0.0576
Schistosoma mansoni hypothetical protein 0.2125 0.2527 0.7125
Brugia malayi ecdysteroid receptor 0.0084 0.0081 0.0576
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0029 0.029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0048 0.0223
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0033 0.0236
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0067 0.006 0.0431
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0022 0.0063
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0022 0.0256
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Entamoeba histolytica hypothetical protein 0.0097 0.0096 0.114
Schistosoma mansoni nocturnin 0.0023 0.0008 0.0022
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0025 0.0074
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0232
Schistosoma mansoni nuclear hormone receptor 0.004 0.0027 0.0077
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0007 0.0053
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0026 0.0011 0.0078
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0029 0.0334
Echinococcus granulosus long chain fatty acid transport protein 4 0.0752 0.0882 0.2486
Brugia malayi hypothetical protein 0.0471 0.0545 0.3884
Leishmania major hypothetical protein, conserved 0.0023 0.0007 0.0053
Onchocerca volvulus 0.0026 0.0011 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0055 0.0156
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.074 0.0867 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0026 0.0011 0.0044
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0099 0.1095
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0404 0.0464 0.1309
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0023 0.0008 0.0022
Echinococcus multilocularis synaptojanin 1 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0057 0.0048 0.0318
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0025 0.0254
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0008 0.0085
Onchocerca volvulus 0.0138 0.0145 0.1607
Brugia malayi MH2 domain containing protein 0.0051 0.004 0.0288
Brugia malayi Bromodomain containing protein 0.0127 0.0132 0.0941
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0163 0.0779
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0016 0.0016
Echinococcus multilocularis deoxyribonuclease 1 2 0.0023 0.0008 0.0008
Brugia malayi RNA binding protein 0.0063 0.0055 0.0394
Brugia malayi ecdysone receptor 0.004 0.0027 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.2809 0.3348 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0091 0.0089 0.0264
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0029 0.029
Echinococcus granulosus replication factor c subunit 1 0.0029 0.0014 0.0041
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Plasmodium falciparum importin beta, putative 0.0119 0.0123 0.0365
Echinococcus multilocularis microtubule associated protein 2 0.2975 0.3547 0.3547
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0084 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0141 0.0148 0.1512
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0026 0.0011 0.0011
Brugia malayi SET domain containing protein 0.0017 0.0001 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0522 0.0606 0.2917
Brugia malayi MH2 domain containing protein 0.0743 0.0871 0.6213
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0015 0.0062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0058
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0086 0.0082 0.0545
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.011 0.0311
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0004 0.001
Leishmania major RNA-editing complex protein MP100, putative 0.0023 0.0008 0.0064
Schistosoma mansoni intermediate filament proteins 0.0083 0.0079 0.0224
Loa Loa (eye worm) pigment dispersing factor receptor c 0.103 0.1214 0.8054
Trichomonas vaginalis conserved hypothetical protein 0.0125 0.013 0.0618
Brugia malayi Steroid receptor seven-up type 2 0.0084 0.0081 0.0576
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0005 0.0014
Echinococcus granulosus tar DNA binding protein 0.0063 0.0055 0.0156
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0002 0.0007
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0007 0.0021
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.005 0.004 0.0282
Schistosoma mansoni hypothetical protein 0.1231 0.1455 0.4103
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0157 0.0168 0.1793
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0712 0.0833 0.2349
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0061
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0091 0.0089 0.094
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0084 0.0081 0.0228
Loa Loa (eye worm) MH2 domain-containing protein 0.0743 0.0871 0.5779
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0023 0.0008 0.0064
Trypanosoma brucei hypothetical protein, conserved 0.0522 0.0606 0.6522
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Trypanosoma brucei pyruvate kinase 1 0.0034 0.002 0.0199
Schistosoma mansoni hypothetical protein 0.0121 0.0124 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Echinococcus granulosus Smad4 0.0051 0.004 0.0114
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Echinococcus multilocularis cysteine protease 0.0019 0.0002 0.0002
Schistosoma mansoni cript-related 0.0023 0.0008 0.0022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0141 0.0148 0.1512
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0022 0.0144
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0029 0.0014 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0141 0.0148 0.1058
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Brugia malayi Cam kinase protein 1 0.0035 0.0022 0.0155
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0009 0.0076
Mycobacterium ulcerans polyketide synthase Pks9 0.0033 0.0019 0.0188
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0047 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0296 0.0335 0.0944
Brugia malayi Heterochromatin protein 1 0.0073 0.0068 0.0484
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Echinococcus multilocularis geminin 0.2125 0.2527 0.2527
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0084 0.0081 0.0576
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0019 0.0053
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0006
Brugia malayi hypothetical protein 0.0023 0.0007 0.0053
Plasmodium falciparum thioredoxin reductase 0.0063 0.0055 0.0164
Toxoplasma gondii type I fatty acid synthase, putative 0.0036 0.0022 0.0065
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0008 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0137 0.0653
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0055 0.0156
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0022 0.0063
Toxoplasma gondii cathepsin CPC2 0.1068 0.126 0.3764
Onchocerca volvulus 0.0041 0.0029 0.0311
Echinococcus multilocularis thyroid hormone receptor alpha 0.0084 0.0081 0.0081
Entamoeba histolytica hypothetical protein 0.0712 0.0833 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Leishmania major pyruvate kinase 0.0034 0.002 0.0199
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.0027 0.008
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 0.647
Giardia lamblia Pyruvate kinase 0.0034 0.002 0.0059
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0025 0.0285
Echinococcus multilocularis General substrate transporter 0.0094 0.0092 0.0092
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0116 0.0119 0.1416
Schistosoma mansoni zinc finger protein 0.004 0.0027 0.0077
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0091 0.0089 0.0223
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.004 0.0268
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0013 0.0126
Echinococcus granulosus chromobox protein 1 0.0073 0.0068 0.0191
Trichomonas vaginalis set domain proteins, putative 0.0764 0.0896 0.4319
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0022
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0016 0.0045
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0191
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0606 0.0706 0.1992
Leishmania major glucose transporter/membrane transporter D2, putative 0.0034 0.002 0.0198
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0022 0.0098
Echinococcus granulosus Protein patched homolog 1 0.0125 0.013 0.0366
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0008 0.0064
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0037 0.0382
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0015 0.0043
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0026 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0033 0.0219
Brugia malayi conserved hypotetical protein 0.004 0.0027 0.0195
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0053
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0323 0.0367 0.4233
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Schistosoma mansoni protein kinase 0.0035 0.0022 0.0061
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0027 0.0027
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.0545 0.1535
Echinococcus multilocularis FTZ F1 alpha 0.0084 0.0081 0.0081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0008 0.0064
Schistosoma mansoni microtubule-associated protein tau 0.2975 0.3547 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0025 0.0246
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0082 0.0082
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0026 0.0011 0.0031
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.011 0.0112 0.0314
Onchocerca volvulus 0.0091 0.0089 0.0983
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0043 0.012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.001 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0001 0.0002
Trypanosoma brucei RNA editing exonuclease 2 0.0023 0.0008 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0029 0.0029
Brugia malayi hypothetical protein 0.0023 0.0007 0.0053
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0182 0.0198 0.0498
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0026 0.0011 0.0044
Mycobacterium ulcerans glutaminase 0.0264 0.0297 0.3036
Schistosoma mansoni hypothetical protein 0.2125 0.2527 0.7125
Plasmodium vivax transportin, putative 0.0023 0.0007 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.0035 0.0022 0.025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.0088
Echinococcus granulosus sterol regulatory element binding protein 0.0125 0.013 0.0366
Schistosoma mansoni chromosome transmission fidelity factor 0.0029 0.0014 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Toxoplasma gondii patched family protein 0.0018 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0033 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Trypanosoma brucei trypanothione reductase 0.0182 0.0198 0.2122
Onchocerca volvulus 0.0023 0.0008 0.0078
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.002 0.0198
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.002 0.02
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0007 0.0021
Echinococcus granulosus sodium:myo inositol cotransporter 0.0076 0.007 0.0198
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0099 0.1048
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0007 0.0007
Schistosoma mansoni importin beta-1 0.0119 0.0123 0.0346
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.0114 0.0756
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.004 0.0114
Entamoeba histolytica Ran family GTPase 0.0067 0.006 0.0715
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Schistosoma mansoni lamin 0.0083 0.0079 0.0224
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0153 0.0163 0.1082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0098
Echinococcus granulosus synaptojanin 1 0.0023 0.0008 0.0022
Brugia malayi jmjC domain containing protein 0.004 0.0027 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0022 0.0096
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0063 0.0055 0.0395
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0029 0.013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.001 0.0072
Loa Loa (eye worm) beta-lactamase 0.0522 0.0606 0.4018
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0047 0.0132
Loa Loa (eye worm) fatty acid synthase 0.0049 0.0039 0.0257
Loa Loa (eye worm) patched family protein 0.0018 0.0001 0.0006
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0026 0.0011 0.0031
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0037 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0034 0.0101
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0022 0.0214
Giardia lamblia NADH oxidase lateral transfer candidate 0.0063 0.0055 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0168 0.0473
Echinococcus multilocularis importin 5 0.0023 0.0007 0.0007
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0099 0.0099
Giardia lamblia Kinase, PLK 0.0099 0.0099 0.0294
Toxoplasma gondii ATPase, AAA family protein 0.0029 0.0014 0.0042
Onchocerca volvulus 0.0019 0.0002 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0027 0.0181
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0015 0.0162
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0055 0.0367
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0096 0.0454
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0002 0.0007
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0043 0.0043
Loa Loa (eye worm) patched family protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0099 0.0656
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0022 0.0063
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.002 0.0059
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0096 0.0095 0.0268
Echinococcus multilocularis lamin dm0 0.0083 0.0079 0.0079
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0026 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0083 0.0079 0.0526
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0138 0.0145 0.0363
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.017 0.0184 0.1877
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0029 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0081 0.0576
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0075 0.0069 0.0173
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0023 0.0008 0.0029
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0137 0.1461
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0008 0.0022
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0053 0.0043 0.0108
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0096 0.0095 0.0964
Echinococcus multilocularis sterol regulatory element binding protein 0.0125 0.013 0.013
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0007 0.0053
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Brugia malayi CXXC zinc finger family protein 0.0086 0.0083 0.0594
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0009 0.0025
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0048 0.0223
Trichomonas vaginalis glucose transporter, putative 0.0034 0.002 0.0088
Brugia malayi DKFZp564C0469 protein 0.0029 0.0014 0.0103
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0027 0.0077
Trichomonas vaginalis helicase, putative 0.002 0.0003 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0606 0.0706 0.0706
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0606 0.0706 0.4686
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0027 0.0195
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0137 0.0386
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0008 0.0029
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0007 0.0007
Brugia malayi hypothetical protein 0.0712 0.0833 0.5942
Brugia malayi Smad1 0.0051 0.004 0.0288
Onchocerca volvulus 0.0023 0.0008 0.0078
Schistosoma mansoni cpg binding protein 0.0091 0.0089 0.0251
Schistosoma mansoni cpg binding protein 0.0091 0.0089 0.0251
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Schistosoma mansoni importin-beta 2 0.0023 0.0007 0.0019
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0029 0.0285
Loa Loa (eye worm) hypothetical protein 0.0086 0.0082 0.0545
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0048 0.0223
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Brugia malayi Carboxylesterase family protein 0.0139 0.0146 0.1044
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0091 0.0089 0.0089
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0026 0.0011 0.0031
Mycobacterium tuberculosis Possible penicillin-binding protein 0.3335 0.3979 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0032 0.0145
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0002 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0034 0.002 0.0198
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0137 0.0386
Echinococcus granulosus sodium:glucose cotransporter 2 0.0076 0.007 0.0198
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0036 0.0023 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0084 0.0081 0.0576
Echinococcus granulosus peregrin 0.0127 0.0132 0.0372
Leishmania major hypothetical protein, conserved 0.0023 0.0008 0.0064
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.004 0.0028 0.0311
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0117 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Loa Loa (eye worm) glutaminase 2 0.0264 0.0297 0.1969
Brugia malayi mbt repeat family protein 0.0046 0.0035 0.0249
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0041 0.0029 0.0071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Schistosoma mansoni nuclear hormone receptor 0.004 0.0027 0.0077
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0029 0.0014 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0163 0.0779
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.004 0.0114
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0522 0.0606 0.1708
Echinococcus granulosus cathepsin l1 0.0019 0.0002 0.0007
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0023 0.0008 0.0022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0033 0.0357
Plasmodium falciparum hexose transporter 0.0109 0.011 0.0327
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0091 0.0089 0.094
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0215 0.1029
Plasmodium vivax replication factor C subunit 1, putative 0.0029 0.0014 0.0042
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.017 0.0184 0.2113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0027 0.0195
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0326 0.037 0.037
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.011 0.0311
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.004 0.0028 0.0082
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0026 0.0011 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0081 0.0228
Mycobacterium ulcerans lipase LipD 0.0522 0.0606 0.6204
Brugia malayi nuclear receptor RXR 0.0045 0.0033 0.0236
Loa Loa (eye worm) hypothetical protein 0.0119 0.0123 0.0814
Onchocerca volvulus 0.0019 0.0002 0.0017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0027 0.0277
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.001 0.0027
Onchocerca volvulus 0.0096 0.0095 0.1051
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0026 0.0011 0.0031
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0027 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0067 0.006 0.0179
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0013 0.0094
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.1068 0.126 0.3764
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0082 0.0243
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0104 0.031
Brugia malayi Nuclear hormone receptor E75 0.004 0.0027 0.0195
Brugia malayi chromobox protein homolog 3 0.0041 0.0029 0.0207
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0068 0.045
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0048 0.0038 0.0094
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0012 0.0012
Trypanosoma cruzi importin beta-1 subunit, putative 0.0097 0.0096 0.1014
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0002 0.0005
Plasmodium falciparum mitogen-activated protein kinase 2 0.0178 0.0193 0.0574
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0043 0.0043
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0029 0.0014 0.0061
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0026 0.0011 0.0072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0522 0.0606 0.1708
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0215 0.1029
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0063 0.0055 0.0055
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0023 0.0008 0.0029
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0141 0.0148 0.1512
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0053 0.0043 0.0108
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0026 0.0011 0.0078
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0008 0.0022
Echinococcus granulosus Niemann Pick C1 protein 0.0292 0.0329 0.0928
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Echinococcus multilocularis chromobox protein 1 0.0073 0.0068 0.0068
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0023 0.0008 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.074 0.0867 0.2177
Echinococcus multilocularis muscleblind protein 0.0904 0.1063 0.1063
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0012 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0712 0.0833 0.0833
Brugia malayi jmjC domain containing protein 0.004 0.0027 0.0196
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0023 0.0008 0.0064
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.069 0.0807 0.5351
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0022
Onchocerca volvulus 0.0399 0.0458 0.5107
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0007 0.0053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0054 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1745 0.2072 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0084 0.0081 0.0576
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0037 0.0265
Schistosoma mansoni smad 0.0023 0.0007 0.0019
Mycobacterium tuberculosis Probable lipase LipD 0.0522 0.0606 0.1522
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0002 0.0001
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0051
Entamoeba histolytica acyl-CoA synthetase, putative 0.0146 0.0154 0.1844
Echinococcus granulosus nibrin 0.0029 0.0014 0.0041
Brugia malayi hypothetical protein 0.0045 0.0033 0.0236
Brugia malayi hypothetical protein 0.0045 0.0033 0.0236
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.011 0.0311
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0025 0.0246
Brugia malayi Latrophilin receptor protein 2 0.0326 0.037 0.2641
Loa Loa (eye worm) hypothetical protein 0.0904 0.1063 0.7053
Loa Loa (eye worm) hypothetical protein 0.0292 0.0329 0.2184
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Brugia malayi Muscleblind-like protein 0.0904 0.1063 0.7583
Schistosoma mansoni protein kinase 0.0035 0.0022 0.0061
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0084 0.0081 0.0228
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.0081 0.0228
Brugia malayi nuclear hormone receptor 0.004 0.0027 0.0195
Loa Loa (eye worm) histone methyltransferase 0.003 0.0016 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0034
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0029 0.0014 0.0137
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0137 0.1636
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0026 0.0011 0.0044
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0002 0.0002
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0752 0.0882 0.9503
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.017 0.0184 0.0461
Loa Loa (eye worm) hypothetical protein 0.0085 0.0082 0.0544
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0025 0.011
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0096 0.0095 0.0964
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0062 0.0054 0.0136
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0027 0.0077
Onchocerca volvulus 0.0764 0.0896 1
Leishmania major glucose transporter, lmgt1 0.0034 0.002 0.0198
Schistosoma mansoni rab6-interacting 0.0041 0.0029 0.0081
Mycobacterium ulcerans pyruvate kinase 0.0034 0.002 0.0199
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0137 0.0653
Schistosoma mansoni hypothetical protein 0.0041 0.0029 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0081 0.0081
Entamoeba histolytica hypothetical protein 0.0024 0.0009 0.0095
Schistosoma mansoni GTP-binding protein alpha subunit 0.0026 0.0011 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0168 0.0802
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0063 0.0055 0.0579
Trypanosoma cruzi lanosterol synthase, putative 0.0212 0.0234 0.2503
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0022 0.0061
Schistosoma mansoni lipoxygenase 0.0115 0.0117 0.033
Loa Loa (eye worm) jmjC domain-containing protein 0.0154 0.0165 0.1092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0091 0.0089 0.0223
Brugia malayi jmjC domain containing protein 0.0154 0.0165 0.1175
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.019
Brugia malayi hypothetical protein 0.0041 0.0029 0.0205
Plasmodium vivax pyruvate kinase, putative 0.0034 0.002 0.0059
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0007 0.0019
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0009 0.0081
Schistosoma mansoni pyruvate kinase 0.0034 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0076 0.007 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0104 0.1109
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0007 0.0021
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0116 0.0119 0.1263
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Schistosoma mansoni hypothetical protein 0.0326 0.037 0.1044
Brugia malayi MH2 domain containing protein 0.0051 0.004 0.0288
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0416 0.0478 0.1202
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0137 0.0653
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0124 0.0349
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0141 0.0148 0.1703
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0125 0.013 0.086
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.001 0.0089
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.005 0.004 0.0396
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0012 0.0083
Echinococcus granulosus jumonji domain containing 1A 0.004 0.0027 0.0077
Schistosoma mansoni polycystin 1-related 0.0041 0.0029 0.0081
Loa Loa (eye worm) hypothetical protein 0.0326 0.037 0.2456
Trichomonas vaginalis penicillin-binding protein, putative 0.0522 0.0606 0.2917
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0137 0.0909
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0001 0.0001
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0091 0.0089 0.094
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0091 0.0089 0.094
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0141 0.0148 0.0372
Leishmania major endonuclease/exonuclease protein-like protein 0.0023 0.0008 0.0064
Giardia lamblia Encystation-specific protease 0.1068 0.126 0.3764
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0053 0.0043 0.0489
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Mycobacterium tuberculosis Probable reductase 0.0416 0.0478 0.1202
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0026 0.0011 0.0031
Echinococcus granulosus sodium:glucose cotransporter 0.0076 0.007 0.0198
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0416 0.0478 0.5517
Onchocerca volvulus Bile acid receptor homolog 0.0084 0.0081 0.0892
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0022 0.0063
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0116 0.0119 0.0353
Echinococcus granulosus translational activator gcn1 0.0023 0.0007 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0008 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0061
Echinococcus granulosus dna polymerase eta 0.0041 0.0029 0.0081
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.004 0.0268
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0027 0.0012 0.0079
Loa Loa (eye worm) Smad1 0.0051 0.004 0.0268
Onchocerca volvulus 0.0297 0.0336 0.374
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0023 0.0008 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0041 0.0188
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0019 0.0053
Schistosoma mansoni synaptojanin 0.0023 0.0008 0.0022
Entamoeba histolytica HEAT repeat domain containing protein 0.0023 0.0007 0.007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.0204 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0007 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0047 0.0117
Echinococcus multilocularis beta adrenergic receptor kinase 0.0027 0.0012 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0081 0.0081
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0007 0.0049
Mycobacterium tuberculosis Conserved protein 0.0522 0.0606 0.1522
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0072
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Brugia malayi Probable ClpP-like protease 0.0085 0.0082 0.0584
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0026 0.0011 0.0044
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0137 0.1573
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0182
Mycobacterium ulcerans hypothetical protein 0.0141 0.0148 0.1512
Brugia malayi phosphofructokinase 0.0131 0.0137 0.0978
Brugia malayi 6-phosphofructokinase 0.0131 0.0137 0.0978
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0028 0.0283
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0008 0.0022
Echinococcus granulosus expressed protein 0.0451 0.052 0.1467
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.012 0.0124 0.0882
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0091 0.0089 0.0902
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Schistosoma mansoni Smad4 0.0051 0.004 0.0114
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0067 0.006 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0055 0.0156
Brugia malayi hypothetical protein 0.0041 0.0029 0.0205
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0023 0.0008 0.0064
Leishmania major hypothetical protein, conserved 0.0023 0.0008 0.0064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0048 0.0223
Echinococcus multilocularis protein dispatched 1 0.0143 0.0151 0.0151
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0074 0.0185
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Echinococcus granulosus lysine specific demethylase 5A 0.0154 0.0165 0.0464
Loa Loa (eye worm) steroid hormone receptor 0.0084 0.0081 0.0535
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0002 0.0002
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0029 0.0291
Brugia malayi protein C24B5.3 0.0018 0.0001 0.0006
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0027 0.0012 0.0079
Loa Loa (eye worm) hypothetical protein 0.0104 0.0104 0.0693
Loa Loa (eye worm) PHD-finger family protein 0.0123 0.0128 0.0847
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0007 0.0019
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0137 0.0909
Echinococcus multilocularis beta LACTamase domain containing family member 0.0522 0.0606 0.0606
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0026 0.0011 0.0072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0141 0.0148 0.0372
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0032 0.0094
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0084 0.0081 0.0081
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.012 0.0124 0.031
Loa Loa (eye worm) DR-78 0.004 0.0027 0.0181
Loa Loa (eye worm) hypothetical protein 0.0062 0.0054 0.036
Plasmodium vivax importin-beta 2, putative 0.0119 0.0123 0.0365
Echinococcus granulosus lamin dm0 0.0083 0.0079 0.0224
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.004 0.0028 0.0276
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0072
Schistosoma mansoni smad1 5 8 and 0.0051 0.004 0.0114
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0157 0.0168 0.1793
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0066 0.0697
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0026 0.0011 0.0044
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Onchocerca volvulus 0.0026 0.0011 0.0112
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0184
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Brugia malayi hypothetical protein 0.0297 0.0336 0.2394
Mycobacterium ulcerans polyketide synthase 0.005 0.004 0.0396
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0026 0.0011 0.0031
Mycobacterium leprae conserved hypothetical protein 0.0522 0.0606 0.6987
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0019 0.0215
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0063 0.0055 0.0156
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0063 0.0055 0.0164
Trichomonas vaginalis antibiotic synthetase, putative 0.0091 0.0089 0.042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0009 0.0034
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.0027 0.0077
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0022 0.0065
Loa Loa (eye worm) hypothetical protein 0.0297 0.0336 0.2226
Loa Loa (eye worm) hypothetical protein 0.0045 0.0033 0.0219
Brugia malayi nuclear receptor NHR-88 0.004 0.0027 0.0195
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0007 0.0045
Loa Loa (eye worm) carboxylesterase 0.0023 0.0008 0.0052
Brugia malayi Nuclear hormone receptor E75 0.004 0.0027 0.0195
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0047 0.0117
Onchocerca volvulus Glucosylceramidase homolog 0.0186 0.0203 0.2257
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0037 0.0109
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0091 0.0089 0.0264
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0008 0.0022
Echinococcus granulosus snurportin 1 0.1274 0.1507 0.425
Brugia malayi hypothetical protein 0.0067 0.006 0.043
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0035 0.038
Loa Loa (eye worm) hypothetical protein 0.0904 0.1063 0.7053
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0067 0.006 0.0179
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0008 0.0022
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0096 0.0095 0.0238
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0153 0.0163 0.0486
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Loa Loa (eye worm) hypothetical protein 0.0091 0.0089 0.0589
Brugia malayi AMP-binding enzyme family protein 0.0141 0.0148 0.1058
Leishmania major trypanothione reductase 0.0182 0.0198 0.2122
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0153 0.0163 0.195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0029 0.0205
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0032 0.0094
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0002 0.0003
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 0.1903
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0063 0.0055 0.0156
Trypanosoma brucei glucose transporter 2A 0.0034 0.002 0.0198
Echinococcus multilocularis lysosomal alpha glucosidase 0.069 0.0807 0.0807
Trichomonas vaginalis glutathione reductase, putative 0.0063 0.0055 0.0259
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0007 0.0021
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0026 0.0011 0.0031
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.0033 0.0094
Brugia malayi nuclear receptor RXR 0.004 0.0027 0.0195
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0002 0.0005
Trypanosoma brucei unspecified product 0.0028 0.0013 0.0126
Toxoplasma gondii histone lysine methyltransferase SET1 0.0171 0.0185 0.055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0018 0.0076
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0076 0.007 0.007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0037 0.0382
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0063 0.0055 0.056
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0007 0.0007
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0007 0.0066
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0022 0.0061
Loa Loa (eye worm) nuclear factor I 0.0028 0.0013 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0002 0.0007
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0034 0.002 0.0088
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0007 0.0007
Leishmania major glucose transporter, lmgt2 0.0034 0.002 0.0198
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0123 0.1306
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0831 0.0976 1
Trichomonas vaginalis replication factor C large subunit, putative 0.0029 0.0014 0.0061
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.004 0.0396
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0008 0.0022
Toxoplasma gondii patched family protein 0.0018 0.0001 0.0001
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.005 0.004 0.0446
Brugia malayi PXA domain containing protein 0.0023 0.0007 0.0053
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0462 0.0534 0.616
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0058 0.0164
Plasmodium vivax acetyl-CoA synthetase, putative 0.0091 0.0089 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Onchocerca volvulus 0.0178 0.0193 0.2146
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0008 0.0019
Brugia malayi photoreceptor-specific nuclear receptor 0.0084 0.0081 0.0576
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.032 0.2281
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0084 0.0081 0.0081
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0027 0.0195
Plasmodium vivax glutathione reductase, putative 0.0182 0.0198 0.0591
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0045 0.0033 0.0219
Schistosoma mansoni retinoic acid receptor RXR 0.0084 0.0081 0.0228
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0063 0.0055 0.056
Echinococcus granulosus FTZ F1 alpha 0.0084 0.0081 0.0228
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.0027 0.0027
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0091 0.0089 0.0902
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0326 0.037 0.1044
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0323 0.0367 0.3759
Onchocerca volvulus 0.004 0.0027 0.0296
Loa Loa (eye worm) G protein alpha subunit 3 0.0026 0.0011 0.0072
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0712 0.0833 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Toxoplasma gondii patched family protein 0.0018 0.0001 0.0001
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0029 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Brugia malayi protein C24B5.3 0.0018 0.0001 0.0006
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.0398 0.4767
Echinococcus granulosus mitogen activated protein kinase 0.0157 0.0168 0.0473
Loa Loa (eye worm) patched family protein 0.0018 0.0001 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0097 0.0289
Schistosoma mansoni patched 1 0.0125 0.013 0.0366
Schistosoma mansoni acetylcholinesterase 0.0023 0.0008 0.0022
Schistosoma mansoni alpha-glucosidase 0.0594 0.0691 0.195
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0061
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0037 0.0382
Schistosoma mansoni topbp1 0.0029 0.0014 0.0041
Entamoeba histolytica acyl-coA synthetase, putative 0.0141 0.0148 0.1771
Schistosoma mansoni RAR-like nuclear receptor 0.0084 0.0081 0.0228
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0033 0.0219
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0026 0.0011 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0084 0.0081 0.0892
Leishmania major protein kinase, putative 0.0035 0.0022 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0022 0.0061
Mycobacterium tuberculosis Probable esterase LipL 0.0522 0.0606 0.1522
Onchocerca volvulus Fatty acid synthase homolog 0.009 0.0088 0.0968
Onchocerca volvulus 0.004 0.0027 0.0296
Loa Loa (eye worm) hypothetical protein 0.0062 0.0054 0.036
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0752 0.0882 0.0882
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0084 0.0081 0.0228
Schistosoma mansoni lipoxygenase 0.0041 0.0029 0.0081
Trichomonas vaginalis penicillin-binding protein, putative 0.0522 0.0606 0.2917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0084 0.0081 0.0228
Schistosoma mansoni coup transcription factor 0.0084 0.0081 0.0228
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0008 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Loa Loa (eye worm) hypothetical protein 0.0123 0.0128 0.0847
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0004 0.001
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0025 0.0069
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0046 0.0034 0.0101
Mycobacterium ulcerans hypothetical protein 0.0522 0.0606 0.6204
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0606 0.0706 0.0706
Plasmodium falciparum acyl-CoA synthetase 0.0062 0.0054 0.0161
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0026 0.0011 0.0078
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0029 0.0014 0.0103
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0018 0.0076
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0035 0.0098
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0096 0.0095 0.0964
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0116 0.0119 0.1209
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0104 0.031
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0096 0.0095 0.0238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0522 0.0606 0.1522
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0026 0.0011 0.0078
Schistosoma mansoni DNA ligase IV 0.0029 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus multilocularis cpg binding protein 0.0091 0.0089 0.0089
Schistosoma mansoni inositol transporter 0.0076 0.007 0.0198
Trypanosoma brucei protein kinase, putative 0.0157 0.0168 0.1793
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0029 0.0081
Brugia malayi Inositol-1 0.0037 0.0025 0.0176
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0002 0.0005
Echinococcus multilocularis tumor protein p63 0.1011 0.1192 0.1192
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0006
Mycobacterium ulcerans Type I modular polyketide synthase 0.005 0.004 0.0396
Echinococcus granulosus jumonji domain containing protein 0.0172 0.0186 0.0523
Loa Loa (eye worm) hypothetical protein 0.0148 0.0157 0.1043
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0018 0.0001 0.0002
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0067 0.006 0.0179
Schistosoma mansoni nuclear receptor 0.004 0.0027 0.0077
Brugia malayi hypothetical protein 0.0018 0.0001 0.0006
Echinococcus granulosus high affinity choline transporter 1 0.0076 0.007 0.0198
Schistosoma mansoni DNA polymerase eta 0.0041 0.0029 0.0081
Brugia malayi hypothetical protein 0.0104 0.0104 0.0745
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0008 0.0029
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0022 0.0065
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.011 0.0311
Plasmodium vivax CDK-related protein kinase 6, putative 0.0464 0.0536 0.1598
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0116 0.0119 0.0298
Onchocerca volvulus 0.0148 0.0157 0.1747
Echinococcus multilocularis phd:f box containing protein 0.004 0.0027 0.0027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0022 0.0065
Schistosoma mansoni jumonji domain containing protein 0.004 0.0027 0.0077
Brugia malayi Myosin head containing protein 0.0018 0.0001 0.0006
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0017 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0084 0.0081 0.0535
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0522 0.0606 0.1522
Toxoplasma gondii protein kinase, putative 0.0309 0.035 0.1045
Schistosoma mansoni phosphatidylserine receptor 0.004 0.0027 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0048 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0029 0.0014 0.0136
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0048 0.0499
Schistosoma mansoni eyes absent homolog 0.0086 0.0082 0.0232
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0096 0.0095 0.0633
Toxoplasma gondii propionate-CoA ligase 0.0091 0.0089 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Echinococcus multilocularis Niemann Pick C1 protein 0.0292 0.0329 0.0329
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0008 0.0022
Schistosoma mansoni inositol monophosphatase 0.0037 0.0025 0.0069
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0028 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) MBCTL1 0.0052 0.0043 0.0282
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0522 0.0606 0.6204
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0097 0.0274
Loa Loa (eye worm) latrophilin receptor protein 2 0.0326 0.037 0.2456
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0137 0.3317
Echinococcus multilocularis translational activator gcn1 0.0023 0.0007 0.0007
Schistosoma mansoni smad1 5 8 and 0.0051 0.004 0.0114
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0081 0.0576
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Onchocerca volvulus 0.0084 0.0081 0.0892
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0009 0.0081
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.001 0.009
Schistosoma mansoni jumonji domain containing protein 0.0321 0.0365 0.1028
Echinococcus granulosus cpg binding protein 0.0091 0.0089 0.0251
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0032 0.0145
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0104 0.031
Brugia malayi beta-lactamase 0.0522 0.0606 0.432
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus multilocularis GPCR, family 2 0.0326 0.037 0.037
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0082 0.0243
Brugia malayi MAP kinase sur-1 0.0157 0.0168 0.1197
Loa Loa (eye worm) hypothetical protein 0.0062 0.0054 0.036
Trypanosoma brucei glycosyl hydrolase-like protein 0.0057 0.0048 0.0499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Brugia malayi TAR-binding protein 0.0063 0.0055 0.0394
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0029 0.0291
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0066 0.0697
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0104 0.031
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0091 0.0089 0.1057
Trypanosoma brucei unspecified product 0.0028 0.0013 0.0126
Schistosoma mansoni nuclear receptor 0.004 0.0027 0.0077
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0027 0.0077
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0002 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0141 0.0148 0.1771
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0033 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0132
Brugia malayi hypothetical protein 0.0018 0.0001 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0154 0.0165 0.0464
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0225
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.005 0.004 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0081 0.0576
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0098 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0063 0.0055 0.0579
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0178 0.0193 0.0574
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0012 0.0048
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0079 0.0526
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0029 0.029
Chlamydia trachomatis DNA ligase 0.0029 0.0014 0.0775
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.004 0.0114
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0062 0.0054 0.6223
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0053 0.0043 0.0434
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0116 0.0119 0.0119
Leishmania major DNA polymerase kappa, putative 0.0041 0.0029 0.029
Brugia malayi Sugar transporter family protein 0.0109 0.011 0.0786
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0137 0.0137
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0075 0.0069 0.0173
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.002 0.0089
Brugia malayi kap beta 3 protein 0.0023 0.0007 0.0048
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0059 0.0616
Loa Loa (eye worm) RecQ helicase 0.0027 0.0012 0.0077
Leishmania major importin beta-1 subunit, putative 0.0097 0.0096 0.1014
Plasmodium falciparum DNase I-like protein, putative 0.0023 0.0008 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0084 0.0081 0.0228
Schistosoma mansoni hypothetical protein 0.0326 0.037 0.1044
Schistosoma mansoni hypothetical protein 0.0121 0.0124 0.035
Leishmania major hypothetical protein, conserved 0.0023 0.0008 0.0064
Echinococcus multilocularis snurportin 1 0.1274 0.1507 0.1507
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0019 0.0207
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0203 0.0971
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0008 0.0008
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0029 0.0029
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0007 0.0021
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0007 0.0027
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0137 0.1461
Echinococcus granulosus ecdysone induced protein 78C 0.0084 0.0081 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0084 0.0081 0.0576
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0029 0.0081
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0004 0.0041
Echinococcus multilocularis chromobox protein 1 0.0073 0.0068 0.0068
Brugia malayi nuclear receptor NHR-88 0.0084 0.0081 0.0576
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Loa Loa (eye worm) acetylcholinesterase 1 0.0139 0.0146 0.0971
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1274 0.1507 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0029 0.0014 0.0163
Brugia malayi CHE-14 protein 0.0125 0.013 0.0925
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0009 0.0025
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0025 0.011
Schistosoma mansoni hypothetical protein 0.0326 0.037 0.1044
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.002 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0022 0.0098
Echinococcus granulosus beta-adrenergic receptor kinase 0.0027 0.0012 0.0034
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0063 0.0055 0.6377
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0051
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0037 0.0109
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0091 0.0089 0.1016
Echinococcus granulosus dnaJ subfamily B 0.1231 0.1455 0.4103
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0007 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0063 0.0055 0.0579
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Brugia malayi Glycosyl hydrolases family 31 protein 0.0057 0.0048 0.0342
Schistosoma mansoni hypothetical protein 0.0704 0.0824 0.2322
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0025 0.0254
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0026 0.0011 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0068 0.0319
Loa Loa (eye worm) hypothetical protein 0.0704 0.0824 0.5463
Echinococcus granulosus bloom syndrome protein 0.0027 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0141 0.0148 0.0984
Echinococcus multilocularis jumonji domain containing protein 0.0172 0.0186 0.0186
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0007 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0141 0.0148 0.1058
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0121 0.0124 0.035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0172
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0084 0.0081 0.0228
Trypanosoma brucei glucosidase, putative 0.0153 0.0163 0.1742
Plasmodium falciparum glutathione reductase 0.0182 0.0198 0.0591
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0282
Trichomonas vaginalis D-aminoacylase, putative 0.0522 0.0606 0.2917
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0027 0.0077
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0323 0.0367 0.1096
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0139 0.0146 0.0413
Echinococcus multilocularis nibrin 0.0029 0.0014 0.0014
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0009 0.0009
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0076 0.007 0.0208
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0029 0.0205
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0019 0.0134
Plasmodium vivax JmjC domain containing protein 0.004 0.0027 0.008
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0008 0.0022
Leishmania major glucose transporter, lmgt3 0.0034 0.002 0.0198
Trypanosoma brucei lanosterol synthase 0.0212 0.0234 0.2502
Loa Loa (eye worm) hypothetical protein 0.0045 0.0033 0.0219
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0033 0.0236
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0002 0.0005
Schistosoma mansoni inositol monophosphatase 0.0037 0.0025 0.0069
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0002 0.0002
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0035 0.0232
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0326 0.037 0.2641
Onchocerca volvulus 0.0083 0.0079 0.0877
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Mycobacterium ulcerans thioesterase 0.0042 0.003 0.0294
Echinococcus granulosus AMP dependent ligase 0.0018 0.0001 0.0002
Toxoplasma gondii hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0086 0.0082 0.0586
Plasmodium vivax thioredoxin reductase, putative 0.0182 0.0198 0.0591
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Brugia malayi beta-lactamase family protein 0.0522 0.0606 0.432
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0079 0.0566
Treponema pallidum fructose-bisphosphate aldolase 0.0349 0.0398 1
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Brugia malayi Pre-SET motif family protein 0.0672 0.0785 0.5598
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0153 0.0163 0.195
Onchocerca volvulus 0.0086 0.0083 0.0921
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0072
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0522 0.0606 0.4018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0084 0.0081 0.0535
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0035 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0097 0.0274
Echinococcus granulosus transportin 1 0.0023 0.0007 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0034 0.002 0.0088
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0099 0.0705
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0002 0.0017
Treponema pallidum exodeoxyribonuclease (exoA) 0.0116 0.0119 0.2848
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0062 0.0054 0.0548
Trypanosoma cruzi trypanothione reductase, putative 0.0182 0.0198 0.2123
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.2809 0.3348 1
Schistosoma mansoni neutral sphingomyelinase 0.0023 0.0008 0.0022
Brugia malayi hypothetical protein 0.004 0.0027 0.0195
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.012 0.0124 0.1315
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.002 0.0049
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0139 0.0146 0.0971
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Onchocerca volvulus 0.0032 0.0018 0.0196
Onchocerca volvulus 0.0522 0.0606 0.6758
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0104 0.1109
Giardia lamblia Replication factor C, subunit 1 0.0029 0.0014 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0053 0.0043 0.0108
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0022 0.0065
Echinococcus granulosus intermediate filament protein 0.0083 0.0079 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Trichomonas vaginalis mercuric reductase, putative 0.0063 0.0055 0.0259
Trichomonas vaginalis ran, putative 0.0067 0.006 0.0283
Brugia malayi nuclear receptor NHR-67 0.004 0.0027 0.0195
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0076 0.007 0.0466
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0084 0.0081 0.0228
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0029 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0023 0.0008 0.0051
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.0079
Mycobacterium tuberculosis Probable thioesterase TesA 0.0042 0.003 0.0074
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0091 0.0255
Plasmodium falciparum replication factor C subunit 1, putative 0.0029 0.0014 0.0042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0051
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0123 0.1306
Echinococcus multilocularis replication factor c subunit 1 0.0029 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.0088
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0404 0.0464 0.0464
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0099 0.1048
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0007 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0008 0.0064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0084 0.0081 0.0228
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Brugia malayi Carboxylesterase family protein 0.0139 0.0146 0.1044
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0027
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0023 0.0008 0.0082
Trypanosoma brucei polo-like protein kinase 0.0099 0.0099 0.1048
Echinococcus multilocularis Niemann Pick C1 protein 0.0417 0.0479 0.0479
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0048 0.0038 0.0094
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0002 0.0016
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0117 0.0117
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.0036 0.01
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0033 0.0093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0076
Brugia malayi Patched related family protein 10 0.0018 0.0001 0.0006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0029 0.0315
Echinococcus granulosus expressed conserved protein 0.0274 0.0308 0.0869
Treponema pallidum NADH oxidase 0.0063 0.0055 0.1223
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0035 0.0098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0027 0.0077
Mycobacterium ulcerans esterase/lipase LipP 0.0522 0.0606 0.6204
Loa Loa (eye worm) acetyltransferase 0.0148 0.0157 0.1043
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0006
Trichomonas vaginalis antibiotic synthetase, putative 0.0091 0.0089 0.042
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0123 0.0128 0.036
Schistosoma mansoni carbon catabolite repressor protein 0.0023 0.0008 0.0022
Onchocerca volvulus 0.0076 0.007 0.0775
Brugia malayi hypothetical protein 0.0018 0.0001 0.0006
Echinococcus multilocularis PHD finger protein rhinoceros 0.0123 0.0128 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0084 0.0081 0.0576
Toxoplasma gondii hypothetical protein 0.0029 0.0015 0.0043
Trichomonas vaginalis maltase-glucoamylase, putative 0.0057 0.0048 0.0223
Toxoplasma gondii ABC1 family protein 0.0522 0.0606 0.1808
Brugia malayi Importin beta-1 subunit 0.0119 0.0123 0.0876
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1186 0.1402 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0019 0.0019
Giardia lamblia Fructose-bisphosphate aldolase 0.0349 0.0398 0.1186
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.002 0.0217
Loa Loa (eye worm) kap beta 3 protein 0.0023 0.0007 0.0045
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0026 0.0011 0.0011
Loa Loa (eye worm) sugar transporter 0.0109 0.011 0.0731
Mycobacterium ulcerans acyl-CoA synthetase 0.0141 0.0148 0.1512
Brugia malayi AMP-binding enzyme family protein 0.0138 0.0145 0.1032
Brugia malayi Doublecortin family protein 0.0041 0.0029 0.0205
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0026 0.0011 0.0044
Echinococcus multilocularis mitogen activated protein kinase 3 0.0157 0.0168 0.0168
Schistosoma mansoni alpha glucosidase 0.0153 0.0163 0.046
Echinococcus multilocularis traf and tnf receptor associated protein 0.0023 0.0008 0.0008
Plasmodium vivax exodeoxyribonuclease III, putative 0.0023 0.0008 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0029 0.0084
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0023 0.0008 0.0022
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0182
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0033 0.0019 0.0212
Leishmania major acetyl-CoA synthetase, putative 0.0091 0.0089 0.094
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0055 0.0055
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0091 0.0089 0.0902
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0026 0.0011 0.0031
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0043 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.002 0.0145
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0097 0.0274
Onchocerca volvulus 0.0104 0.0105 0.1159
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0007 0.0007
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.011 0.011
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0007 0.0045
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0084 0.0081 0.0535
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0027 0.0077
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0072
Leishmania major cathepsin L-like protease 0.0072 0.0066 0.0697
Schistosoma mansoni lamin 0.0083 0.0079 0.0224
Onchocerca volvulus 0.0029 0.0014 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0018 0.0076
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0002 0.0017
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0104 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.0091 0.0089 0.0902
Mycobacterium tuberculosis Probable oxidoreductase 0.0462 0.0534 0.1342
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0007 0.0021
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0043 0.0304
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0007 0.0021
Schistosoma mansoni Smad4 0.0023 0.0007 0.0019
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0168 0.1793
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0025 0.0247
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0157 0.0168 0.05
Schistosoma mansoni cpg binding protein 0.0086 0.0083 0.0235
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0036 0.0023 0.0056
Echinococcus multilocularis high affinity choline transporter 1 0.0076 0.007 0.007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.001 0.004
Onchocerca volvulus Alhambra homolog 0.0123 0.0128 0.1416
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0027 0.0012 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0084 0.0081 0.0535
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1068 0.126 0.3764
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0014 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0029 0.029
Brugia malayi glutathione reductase 0.0182 0.0198 0.1415
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0039
Loa Loa (eye worm) carboxylesterase 0.0139 0.0146 0.0971
Schistosoma mansoni chromobox protein 0.0073 0.0068 0.0191
Schistosoma mansoni sodium/solute symporter 0.0076 0.007 0.0198
Loa Loa (eye worm) importin-beta domain-containing protein 0.0023 0.0007 0.0045
Schistosoma mansoni topbp1 0.0029 0.0014 0.0041
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0008 0.0022
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0027 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0116 0.0119 0.1263
Plasmodium vivax vivapain-2 0.0019 0.0002 0.0006
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0019 0.0134
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.002 0.02
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0025 0.0072
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0146 0.0146
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0416 0.0478 0.1202
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.002 0.0217
Brugia malayi Niemann-Pick C1 protein precursor 0.0292 0.0329 0.2349
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0157 0.0157
Brugia malayi CCR4 0.0023 0.0008 0.0055
Toxoplasma gondii facilitative glucose transporter GT1 0.0109 0.011 0.0327
Leishmania major hypothetical protein, conserved 0.004 0.0027 0.0277
Brugia malayi topoisomerase 0.0029 0.0014 0.0103
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0027 0.0182
Schistosoma mansoni ran 0.0067 0.006 0.017
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0022 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0013 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0063 0.0055 0.0579
Loa Loa (eye worm) oxidoreductase 0.0091 0.0089 0.0589
Brugia malayi glutaminase DH11.1 0.0264 0.0297 0.2117
Echinococcus granulosus carboxylesterase 5A 0.0139 0.0146 0.0413
Loa Loa (eye worm) hypothetical protein 0.0791 0.0928 0.6154
Echinococcus granulosus pyruvate kinase 0.0034 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Plasmodium falciparum phd finger protein, putative 0.0123 0.0128 0.038
Brugia malayi latrophilin 2 splice variant baaae 0.0704 0.0824 0.5874
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0157 0.0168 0.1793
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0025 0.0074
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0027 0.0296
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0029 0.0014 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0141 0.0148 0.1512
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.002 0.005
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0081 0.0228
Giardia lamblia hypothetical protein 0.0023 0.0008 0.0022
Echinococcus multilocularis mitogen activated protein kinase 0.0157 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0125 0.013 0.086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Brugia malayi Cytochrome P450 family protein 0.0026 0.0011 0.0079
Brugia malayi steroid hormone receptor 0.0084 0.0081 0.0576
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0081 0.0576
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0096
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Loa Loa (eye worm) pyruvate kinase 0.0034 0.002 0.0135
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0026 0.0011 0.0044
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0063 0.0055 0.0164
Trypanosoma brucei C-8 sterol isomerase, putative 0.0791 0.0928 1
Echinococcus multilocularis neutral sphingomyelinase 0.0023 0.0008 0.0008
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0028 0.0014 0.0034
Brugia malayi intermediate filament protein 0.0083 0.0079 0.0566
Echinococcus granulosus geminin 0.2125 0.2527 0.7125
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0007 0.0049
Loa Loa (eye worm) glutathione reductase 0.0182 0.0198 0.1316
Schistosoma mansoni hypothetical protein 0.1274 0.1507 0.425
Mycobacterium leprae Probable lipase LipE 0.0522 0.0606 0.6987
Schistosoma mansoni Smad4 0.0023 0.0007 0.0019
Loa Loa (eye worm) cysteine protease 0.0019 0.0002 0.0016
Onchocerca volvulus 0.0023 0.0008 0.0077
Brugia malayi tailless protein 0.004 0.0027 0.0195
Echinococcus granulosus acetylcholinesterase 0.0139 0.0146 0.0413
Leishmania major 4-coumarate:coa ligase-like protein 0.0141 0.0148 0.1582
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0029 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0168 0.0802
Entamoeba histolytica G protein alpha subunit, putative 0.0026 0.0011 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0522 0.0606 0.6522
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0022 0.1831
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Schistosoma mansoni survival motor neuron protein 0.0096 0.0095 0.0268
Echinococcus multilocularis dna polymerase eta 0.0041 0.0029 0.0029
Toxoplasma gondii FATC domain-containing protein 0.0025 0.001 0.0029
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0063 0.0055 0.0164
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.032 0.2122
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0002 0.0013
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0091 0.0089 0.094
Plasmodium falciparum protein kinase 7 0.0309 0.035 0.1045
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.004 0.004
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0095 0.0677
Leishmania major glycosyl hydrolase-like protein 0.0057 0.0048 0.0499
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0081 0.0576
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0009 0.0075
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0099 0.1048
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.0079
Toxoplasma gondii PHD-finger domain-containing protein 0.004 0.0028 0.0082
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0084 0.0081 0.0081
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0157 0.0168 0.1793
Echinococcus multilocularis transportin 1 0.0023 0.0007 0.0007
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Echinococcus multilocularis expressed protein 0.0026 0.0011 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0141 0.0148 0.1582
Mycobacterium ulcerans acyl-CoA synthetase 0.0141 0.0148 0.1512
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0063 0.0055 0.0579
Echinococcus granulosus RUN 0.0041 0.0029 0.0081
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0091 0.0089 0.094
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0048 0.0223
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0007 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0013 0.0126
Onchocerca volvulus Huntingtin homolog 0.0139 0.0146 0.1622
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0057 0.0048 0.0527
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0831 0.0976 0.6472
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0157 0.0443
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.1068 0.126 0.3764
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0026 0.0011 0.0011
Plasmodium vivax hexose transporter 0.0109 0.011 0.0327
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Schistosoma mansoni glucose transport protein 0.0109 0.011 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0026 0.0011 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0029 0.029
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Brugia malayi Patched family protein 0.0018 0.0001 0.0006
Onchocerca volvulus 0.0019 0.0002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0522 0.0606 0.1808
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0026 0.0011 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0066 0.0697
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0008 0.0071
Toxoplasma gondii cathepsin CPL 0.0019 0.0002 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0002 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0008 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0099 0.1177
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0067 0.006 0.0401
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0043 0.012
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0007 0.0021
Brugia malayi hypothetical protein 0.0018 0.0001 0.0006
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0025 0.0254
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0067 0.006 0.0633
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0088
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.0181
Loa Loa (eye worm) hypothetical protein 0.0139 0.0146 0.0969
Loa Loa (eye worm) hypothetical protein 0.0084 0.0081 0.0535
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0007 0.0049
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0037 0.0382
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0137 0.0344
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0007 0.0021
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0002 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0055 0.0156
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0053 0.0043 0.0434
Leishmania major C-8 sterol isomerase-like protein 0.0791 0.0928 1
Brugia malayi MH2 domain containing protein 0.0023 0.0007 0.0049
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0022 0.0155
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0095 0.0677
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0096 0.0095 0.0964
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0007 0.0049
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0002 0.0006
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0035 0.0098
Schistosoma mansoni gliotactin 0.0023 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0051
Schistosoma mansoni hypothetical protein 0.0326 0.037 0.1044
Brugia malayi Glycosyl hydrolases family 31 protein 0.069 0.0807 0.5753
Brugia malayi Pax transcription activation domain interacting protein 0.0029 0.0014 0.0103
Onchocerca volvulus Putative neutral sphingomyelinase 0.0023 0.0008 0.0077
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0022 0.0063
Echinococcus multilocularis lamin 0.0083 0.0079 0.0079
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0146 0.0146
Trypanosoma brucei glucose transporter, putative 0.0034 0.002 0.0198
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0002 0.0017
Loa Loa (eye worm) fibroinase 0.0019 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0471 0.0545 0.3613
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0035 0.0035
Onchocerca volvulus Huntingtin homolog 0.0139 0.0146 0.1622
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Loa Loa (eye worm) pyruvate kinase 0.0034 0.002 0.0135
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0066 0.0697
Loa Loa (eye worm) inositol-1 0.0037 0.0025 0.0163
Echinococcus multilocularis thioredoxin glutathione reductase 0.0183 0.0199 0.0199
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0157 0.0168 0.1793
Leishmania major GTP-binding protein, putative 0.0067 0.006 0.0633
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0057 0.0048 0.0566
Schistosoma mansoni protein phosphatase 2C 0.004 0.0027 0.0077
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0037 0.0109
Echinococcus multilocularis dnaJ subfamily B 0.1231 0.1455 0.1455
Onchocerca volvulus 0.0026 0.0011 0.0112
Echinococcus multilocularis Smad4 0.0051 0.004 0.004
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0029 0.0072
Echinococcus granulosus lamin 0.0083 0.0079 0.0224
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.002 0.0224
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0025 0.011
Schistosoma mansoni smad 0.0051 0.004 0.0114
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0063 0.0055 0.0579
Plasmodium vivax acyl-CoA synthetase, putative 0.0062 0.0054 0.0161
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0022 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.002 0.0004 0.0009
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0082
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0009 0.0075
Trichomonas vaginalis sucrase-isomaltase, putative 0.0153 0.0163 0.0779
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0082 1
Echinococcus granulosus neutral sphingomyelinase 0.0023 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0049
Schistosoma mansoni protein kinase 0.0035 0.0022 0.0061
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0033 0.0236
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.032 0.1536
Schistosoma mansoni ran 0.0067 0.006 0.017
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.2809 0.3348 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0084 0.0081 0.0892
Brugia malayi Carboxylesterase family protein 0.0023 0.0008 0.0056
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0008 0.0022
Brugia malayi hypothetical protein 0.004 0.0027 0.0195
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0025 0.0025
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.004 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0099 0.0469
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.0398 0.1912
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0007 0.0019
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.002 0.022
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0002 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0061
Entamoeba histolytica protein kinase, putative 0.0035 0.0022 0.025
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0023 0.0008 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Echinococcus granulosus expressed protein 0.0026 0.0011 0.0031
Plasmodium falciparum transportin 0.0023 0.0007 0.0019
Brugia malayi jmjC domain containing protein 0.0404 0.0464 0.3312
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0116 0.0119 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0462 0.0534 0.1342
Brugia malayi Glycosyl hydrolases family 31 protein 0.0153 0.0163 0.1164
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0023 0.0008 0.0022
Toxoplasma gondii patched family protein 0.0018 0.0001 0.0001
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0019 0.0055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0084 0.0081 0.0228
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0009 0.0025
Schistosoma mansoni hypothetical protein 0.0047 0.0036 0.01
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0007 0.0019
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0026 0.0011 0.0072
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0025 0.0074
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0027 0.0077
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0067 0.006 0.0633
Leishmania major acetyl-CoA synthetase, putative 0.0091 0.0089 0.094
Loa Loa (eye worm) RNA binding protein 0.0063 0.0055 0.0367
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.001 0.0028
Onchocerca volvulus 0.0019 0.0002 0.0017
Schistosoma mansoni loxhd1 0.0041 0.0029 0.0081
Echinococcus granulosus importin subunit beta 1 0.0119 0.0123 0.0346
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0606 0.0706 0.1992
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0051
Leishmania major DNA polymerase eta, putative 0.0041 0.0029 0.029
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.2809 0.3348 1
Plasmodium falciparum glutathione reductase 0.0063 0.0055 0.0164
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0029 0.0191
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0017
Schistosoma mansoni alpha-glucosidase 0.0594 0.0691 0.195
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0008 0.0082
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0138 0.0145 0.096
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0027 0.0027
Echinococcus granulosus muscleblind protein 0.0904 0.1063 0.2998
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0051
Brugia malayi beta-lactamase family protein 0.0522 0.0606 0.432
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0026 0.0011 0.0078
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0081 0.0228
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0095 0.0093 0.0664
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0522 0.0606 0.4018
Schistosoma mansoni rab6-interacting 0.0041 0.0029 0.0081
Leishmania major cathepsin L-like protease 0.0072 0.0066 0.0697
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0003
Echinococcus granulosus mitogen activated protein kinase 3 0.0157 0.0168 0.0473
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0168 0.0802
Loa Loa (eye worm) hypothetical protein 0.0212 0.0233 0.1548

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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