Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0252 | 0.1094 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0027 | 0.026 | 0.026 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.2992 | 0.2992 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0606 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.003 | 0.0364 | 0.0365 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0082 | 0.199 | 0.199 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.1245 | 0.1245 |
Onchocerca volvulus | 0.0027 | 0.026 | 0.0745 | |
Brugia malayi | nuclear hormone receptor | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0033 | 0.0441 | 0.1264 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0124 | 0.3345 | 0.3356 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0092 | 0.0092 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0058 | 0.1231 | 0.2506 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0058 | 0.1231 | 0.1235 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0033 | 0.0441 | 0.0442 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0606 | 0.3511 |
Brugia malayi | conserved hypotetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0128 | 0.3482 | 0.3494 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0941 | 0.0941 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Onchocerca volvulus | 0.0049 | 0.0941 | 0.2698 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0058 | 0.1231 | 0.1235 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.026 | 0.0261 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.003 | 0.0364 | 0.0365 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0092 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0519 | 0.0519 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0027 | 0.026 | 0.0261 |
Onchocerca volvulus | 0.0058 | 0.1231 | 0.353 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.3828 | 0.3828 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0092 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0128 | 0.3482 | 0.3494 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0659 | 0.0659 |
Brugia malayi | bHLH-PAS transcription factor | 0.0044 | 0.0801 | 0.0801 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0155 | 0.4316 | 0.8787 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.4569 | 0.4584 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.4569 | 0.4584 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0173 | 0.4912 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | ecdysone receptor | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1557 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0698 | 0.2003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3702 | 0.3702 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | nuclear receptor RXR | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | tailless protein | 0.0027 | 0.026 | 0.026 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0092 | 0.0092 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0092 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | 0.0027 | 0.026 | 0.0745 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0052 | 0.1048 | 0.1048 |
Brugia malayi | nuclear receptor NHR-88 | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.3482 | 0.3482 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0058 | 0.1231 | 0.2506 |
Loa Loa (eye worm) | glutamate receptor | 0.0082 | 0.199 | 0.199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1245 | 0.1245 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.026 | 0.0261 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0058 | 0.1231 | 0.1235 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0092 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Onchocerca volvulus | 0.003 | 0.0344 | 0.0987 | |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0441 | 0.0898 |
Echinococcus granulosus | FTZ F1 alpha | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0027 | 0.026 | 0.026 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0092 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0099 | 0.254 | 0.5171 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.1557 | 0.1557 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0092 | 0.5 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0092 | 0.0092 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0129 | 0.3503 | 0.3515 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0027 | 0.026 | 0.0261 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0049 | 0.0942 | 0.0945 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0049 | 0.0942 | 0.1919 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0052 | 0.1048 | 0.1048 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0132 | 0.3598 | 0.3598 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.3828 | 0.3828 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0099 | 0.254 | 0.254 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0033 | 0.0441 | 0.1264 |
Echinococcus granulosus | tumor protein p63 | 0.0332 | 0.9967 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.3828 | 0.3828 |
Schistosoma mansoni | coup transcription factor | 0.0058 | 0.1231 | 0.2506 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.1697 | 0.1703 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0092 | 0.1764 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0163 | 0.4569 | 0.4569 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0941 | 0.1915 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0058 | 0.1231 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1557 | 0.3171 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0519 | 0.0521 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0441 | 0.0441 |
Brugia malayi | ecdysteroid receptor | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | nuclear receptor NHR-88 | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0058 | 0.1231 | 0.2506 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Schistosoma mansoni | nuclear hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0092 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Onchocerca volvulus | 0.0129 | 0.3487 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0129 | 0.3503 | 0.3515 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0027 | 0.026 | 0.0261 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0027 | 0.026 | 0.0529 |
Echinococcus granulosus | single minded 2 | 0.0044 | 0.0801 | 0.0804 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0519 | 0.0521 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1557 | 0.3171 |
Brugia malayi | PAS domain containing protein | 0.006 | 0.1296 | 0.1296 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0092 | 0.0092 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0698 | 0.414 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0606 | 0.0606 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0058 | 0.1231 | 0.2506 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0058 | 0.1231 | 0.2506 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.1697 | 0.1703 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0344 | 0.0344 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0606 | 0.1739 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0092 | 0.0186 |
Brugia malayi | nuclear hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0519 | 0.1056 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0092 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0058 | 0.1231 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0027 | 0.026 | 0.0745 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0364 | 0.0741 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0033 | 0.0441 | 0.0441 |
Brugia malayi | nuclear receptor RXR | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.1557 | 0.1557 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0155 | 0.4316 | 0.433 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1048 | 0.1048 |
Mycobacterium ulcerans | putative regulatory protein | 0.0044 | 0.0801 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0058 | 0.1231 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0092 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0027 | 0.026 | 0.0745 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1557 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0519 | 0.1056 |
Loa Loa (eye worm) | glutamate receptor | 0.008 | 0.1933 | 0.1933 |
Brugia malayi | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | 0.0045 | 0.0818 | 0.2345 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.003 | 0.0364 | 0.0741 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3009 | 0.3009 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0058 | 0.1231 | 0.1235 |
Schistosoma mansoni | thyroid hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0113 | 0.2992 | 0.2992 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0049 | 0.0942 | 0.0945 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0092 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0252 | 0.1094 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0092 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.3487 | 0.3487 |
Schistosoma mansoni | zinc finger protein | 0.0027 | 0.026 | 0.0529 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0606 | 0.0606 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0698 | 0.414 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0033 | 0.0441 | 0.0442 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0659 | 0.1341 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0052 | 0.1048 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0659 | 0.0659 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0109 | 0.2875 | 0.5854 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0063 | 0.1383 | 0.1383 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.1245 | 0.1245 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Schistosoma mansoni | nuclear receptor | 0.0027 | 0.026 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.1245 | 0.1245 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0027 | 0.026 | 0.0261 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0027 | 0.026 | 0.0529 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0092 | 0.5 |
Loa Loa (eye worm) | DR-78 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | steroid hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0044 | 0.0801 | 0.0804 |
Schistosoma mansoni | single-minded | 0.006 | 0.1296 | 0.2638 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0027 | 0.026 | 0.026 |
Echinococcus multilocularis | tumor protein p63 | 0.0332 | 0.9967 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0058 | 0.1231 | 0.1231 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 28.1838 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.