Detailed information for compound 1245655

Basic information

Technical information
  • TDR Targets ID: 1245655
  • Name: [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)- 2-oxoethyl]-2-(hydroxymethyl)oxan-4-yl] tetra decanoate
  • MW: 431.563 | Formula: C22H41NO7
  • H donors: 4 H acceptors: 5 LogP: 4.38 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCC(=O)O[C@@H]1[C@H](CO[C@@H]([C@H]1O)CO)CC(=O)NO
  • InChi: 1S/C22H41NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-20(26)30-22-17(14-19(25)23-28)16-29-18(15-24)21(22)27/h17-18,21-22,24,27-28H,2-16H2,1H3,(H,23,25)/t17-,18+,21+,22+/m0/s1
  • InChiKey: INAPDIIIYSWKOC-XHIHJMKYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)-2-oxo-ethyl]-2-(hydroxymethyl)tetrahydropyran-4-yl] tetradecanoate
  • tetradecanoic acid [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)-2-oxoethyl]-2-(hydroxymethyl)-4-tetrahydropyranyl] ester
  • myristic acid [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)-2-keto-ethyl]-2-methylol-tetrahydropyran-4-yl] ester
  • [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)-2-oxo-ethyl]-2-(hydroxymethyl)oxan-4-yl] tetradecanoate
  • 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL
  • TU-514
  • TUX

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0028 0.0049 0.0277
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0049 0.0277
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.03 0.1713 1
Schistosoma mansoni hypothetical protein 0.0398 0.2311 0.2863
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0078 0.0354 0.0414
Schistosoma mansoni hypothetical protein 0.1213 0.7305 0.9083
Echinococcus multilocularis 0.0028 0.0049 0.0027
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0225 0.1255 0.1549
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0078 0.0354 0.044
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0036 0.0096 0.012
Brugia malayi NADH dehydrogenase subunit 1, identical 0.0039 0.0115 0.0142
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Echinococcus granulosus jun protein 0.0048 0.0172 0.0186
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0049 0.0175 0.0191
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0073 0.0322 0.0386
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0078 0.0354 0.044
Plasmodium falciparum protoporphyrinogen oxidase 0.0034 0.0084 0.0529
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0078 0.0354 0.044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1333 0.8042 1
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0023 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0277 0.0345
Echinococcus multilocularis para nitrobenzyl esterase 0.0225 0.1255 0.1236
Echinococcus granulosus lysine specific demethylase 6a 0.0135 0.07 0.0845
Schistosoma mansoni tyrosine kinase 0.0049 0.0175 0.0204
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0205 0.1133 0.3569
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0886 0.5303 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0029 0.0055 0.0033
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0137 0.0714 1
Brugia malayi Cytochrome P450 family protein 0.0031 0.0066 0.0082
Schistosoma mansoni jumonji/arid domain-containing protein 0.0287 0.1633 0.2019
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Schistosoma mansoni protein phosphatase 2C 0.0098 0.0474 0.0576
Mycobacterium tuberculosis Possible oxidoreductase 0.0034 0.0084 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0148 0.0345
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0179 0.0195
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0083 0.0474
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0144 0.018
Onchocerca volvulus 0.0026 0.0033 0.0065
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0078 0.0354 0.0426
Onchocerca volvulus 0.0078 0.0354 0.2672
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0212
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0034 0.0084 0.0264
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Onchocerca volvulus 0.0036 0.0096 0.0578
Toxoplasma gondii hypothetical protein 0.0049 0.0179 0.0316
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0185
Loa Loa (eye worm) hypothetical protein 0.0113 0.0569 0.0707
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0028 0.0049 0.006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.003 0.0057 0.0035
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0078 0.0354 0.0332
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0028 0.0049 0.0038
Trichomonas vaginalis fk506-binding protein, putative 0.0028 0.0049 0.0071
Leishmania major hypothetical protein, conserved 0.0098 0.0474 0.2702
Schistosoma mansoni neurotransmitter gated ion channel 0.0042 0.0133 0.0151
Brugia malayi hypothetical protein 0.0036 0.0096 0.012
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.0842
Brugia malayi jmjC domain containing protein 0.0135 0.07 0.087
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0025 0.0031
Brugia malayi beta-lactamase family protein 0.0109 0.0541 0.0673
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0078 0.0354 0.0332
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.009 0.0112
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0096 0.0105
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0145 0.0764 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0084 0.0529
Mycobacterium ulcerans hypothetical protein 0.0028 0.0049 0.0153
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0078 0.0354 0.044
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.03 0.1713 0.5398
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.014 0.0797
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Echinococcus multilocularis protoporphyrinogen oxidase 0.0034 0.0084 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0066 0.0082
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0025 0.0031
Trichomonas vaginalis inositol monophosphatase, putative 0.0034 0.0083 0.0166
Brugia malayi Cation transporter family protein 0.0078 0.0354 0.044
Echinococcus granulosus carboxylesterase 5A 0.1333 0.8042 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0144 0.0823
Brugia malayi Probable ClpP-like protease 0.0076 0.0338 0.0421
Mycobacterium ulcerans beta-lactamase 0.0109 0.0541 0.1705
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0053 0.0202 0.0636
Brugia malayi hypothetical protein 0.0225 0.1255 0.1561
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0205 0.1133 0.307
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0179 0.0319
Schistosoma mansoni amine oxidase 0.0034 0.0084 0.009
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0843 0.0823
Brugia malayi Calcitonin receptor-like protein seb-1 0.0358 0.2066 0.257
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Onchocerca volvulus 0.0225 0.1255 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.014 0.0797
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0124 0.0632 0.0761
Onchocerca volvulus 0.0039 0.0115 0.0727
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0205 0.1133 0.3047
Plasmodium falciparum JmjC domain-containing protein, putative 0.0122 0.0622 0.5392
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0025 0.0006
Brugia malayi hypothetical protein 0.0024 0.0025 0.0031
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0042 0.0133 0.0166
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.009 0.0186
Trichomonas vaginalis spcc417.12 protein, putative 0.0225 0.1255 0.3409
Echinococcus granulosus Chromo domain 0.0024 0.0025 0.0004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0034 0.0083 0.0484
Echinococcus multilocularis neuroligin 0.0225 0.1255 0.1236
Brugia malayi excitatory GABA receptor EXP-1A 0.0078 0.0354 0.044
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0096 0.0105
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.0541 0.3083
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.009 0.0149
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0541 0.066
Entamoeba histolytica Ran family GTPase 0.0044 0.0144 0.0336
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0109 0.0545 0.0524
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0025 0.0006
Echinococcus multilocularis epidermal growth factor receptor 0.0049 0.0175 0.0154
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.014 0.0797
Brugia malayi SET domain containing protein 0.0026 0.0033 0.0041
Onchocerca volvulus 0.0036 0.0096 0.0578
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Loa Loa (eye worm) hypothetical protein 0.0087 0.041 0.051
Onchocerca volvulus 0.0109 0.0541 0.4195
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0085 0.0063
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0098 0.0474 0.2702
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0085 0.0089
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.009 0.0068
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0078 0.0354 0.0414
Loa Loa (eye worm) hypothetical protein 0.0037 0.0101 0.0126
Schistosoma mansoni fk506 binding protein 0.0028 0.0049 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0541 0.3083
Schistosoma mansoni gliotactin 0.0225 0.1255 0.1549
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0036 0.0096 0.0092
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Loa Loa (eye worm) glutaminase 2 0.0539 0.3174 0.3947
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0025 0.0004
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0177 0.096 0.094
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0085 0.0541
Schistosoma mansoni hypothetical protein 0.1213 0.7305 0.9083
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Onchocerca volvulus 0.0039 0.0117 0.0744
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0025 0.0006
Loa Loa (eye worm) carboxylesterase 0.0225 0.1255 0.1561
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0036 0.0096 0.0074
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0053 0.0202 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0049 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0287 0.1633 0.2019
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.0541 0.1208
Entamoeba histolytica hypothetical protein 0.0024 0.0025 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0025 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.1002 0.0983
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0135 0.07 0.0857
Echinococcus multilocularis acetylcholinesterase 0.1333 0.8042 0.8037
Echinococcus multilocularis neuropeptide receptor A26 0.0979 0.5871 0.5862
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0172 0.0412
Toxoplasma gondii hypothetical protein 0.0026 0.0035 0.0044
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0034 0.0083 0.0135
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0012 0.0066
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0205 0.1133 1
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0338 0.0617
Brugia malayi hypothetical protein 0.0053 0.0202 0.0251
Leishmania major fk506-binding protein 1-like protein 0.0205 0.1133 0.6453
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0085 0.0484
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0225 0.1255 0.1538
Loa Loa (eye worm) jmjC domain-containing protein 0.014 0.0735 0.0914
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0073 0.0322 0.0386
Schistosoma mansoni inositol monophosphatase 0.0034 0.0083 0.0089
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0078 0.0354 0.044
Plasmodium vivax hypothetical protein, conserved 0.0109 0.0541 0.466
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.1755 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0172 0.0979
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0028 0.0049 0.006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Echinococcus granulosus Chromobox protein 3 0.0024 0.0025 0.0004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0653 0.0799
Brugia malayi Carboxylesterase family protein 0.0225 0.1255 0.1561
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0179 0.0857
Echinococcus granulosus lysine specific demethylase 5A 0.0287 0.1633 0.2008
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0388 0.1009
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0202 0.1599
Onchocerca volvulus 0.0078 0.0354 0.2672
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.0292 0.0529
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.009 0.0514
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0098 0.0474 0.0875
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0205 0.1133 0.6453
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0144 0.0823
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0185
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0083 0.0166
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0084 0.0388 0.4742
Schistosoma mansoni phosphatidylserine receptor 0.0098 0.0474 0.0576
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0241 0.1373
Echinococcus granulosus glycine receptor subunit beta 0.0078 0.0354 0.0414
Loa Loa (eye worm) ACC-1 protein 0.0078 0.0354 0.044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Brugia malayi Heterochromatin protein 1 0.0149 0.0789 0.0982
Schistosoma mansoni chromobox protein 0.0024 0.0025 0.0017
Echinococcus granulosus nAChR subunit 0.0042 0.0133 0.0139
Schistosoma mansoni hypothetical protein 0.0024 0.0022 0.0013
Echinococcus granulosus GPCR family 2 0.0113 0.0569 0.0682
Brugia malayi Furin-like cysteine rich region family protein 0.0091 0.0431 0.0536
Schistosoma mansoni amine oxidase 0.0034 0.0084 0.009
Toxoplasma gondii histone lysine-specific demethylase 0.0034 0.0084 0.0136
Mycobacterium ulcerans formate hydrogenlyase HycD 0.0039 0.0115 0.0361
Echinococcus multilocularis PHD finger protein rhinoceros 0.0068 0.0292 0.027
Plasmodium falciparum importin beta, putative 0.006 0.0241 0.1949
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0078 0.0354 0.0414
Echinococcus multilocularis cpg binding protein 0.0065 0.0274 0.0253
Echinococcus multilocularis fk506 binding protein 0.0205 0.1133 0.1113
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Brugia malayi Bromodomain containing protein 0.0068 0.0292 0.0363
Echinococcus multilocularis geminin 0.1213 0.7305 0.7299
Brugia malayi MH2 domain containing protein 0.0127 0.0655 0.0815
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.006
Onchocerca volvulus 0.0109 0.0541 0.4195
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.2827
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0078 0.0354 0.0426
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Echinococcus granulosus chromobox protein 2 0.0024 0.0025 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.007 0.0129
Brugia malayi hypothetical protein 0.0038 0.0108 0.0134
Loa Loa (eye worm) beta-lactamase 0.0109 0.0541 0.0673
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0078 0.0354 0.044
Echinococcus multilocularis acetylcholinesterase 0.1333 0.8042 0.8037
Brugia malayi hypothetical protein 0.0036 0.0096 0.012
Echinococcus multilocularis lysine specific demethylase 6a 0.0135 0.07 0.0679
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.0541 0.1705
Echinococcus multilocularis jumonji domain containing 1A 0.0181 0.0987 0.0967
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0202 0.1116 0.1096
Brugia malayi jmjC domain containing protein 0.0365 0.2114 0.2629
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0084 0.0388 0.1221
Loa Loa (eye worm) hypothetical protein 0.0037 0.0101 0.0126
Brugia malayi Carboxylesterase family protein 0.0225 0.1255 0.1561
Echinococcus granulosus FK506 binding protein 2 0.0028 0.0049 0.0033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.1002 0.1222
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Schistosoma mansoni ran 0.0044 0.0144 0.0166
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0655 0.0815
Brugia malayi hypothetical protein 0.0039 0.0115 0.0142
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0078 0.0354 0.0332
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0028 0.0049 0.0033
Echinococcus multilocularis jun protein 0.0048 0.0172 0.015
Schistosoma mansoni hypothetical protein 0.0245 0.1373 0.1696
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0144 0.0823
Schistosoma mansoni chromobox protein 0.0149 0.0789 0.0969
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.009 0.0186
Onchocerca volvulus 0.0083 0.0386 0.2937
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Schistosoma mansoni hypothetical protein 0.0035 0.009 0.0097
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0025 0.0031
Schistosoma mansoni tyrosine kinase 0.0029 0.0055 0.0054
Schistosoma mansoni hypothetical protein 0.0637 0.3777 0.4689
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0012 0.0066
Plasmodium vivax JmjC domain containing protein 0.0122 0.0622 0.5392
Loa Loa (eye worm) GABA receptor subunit 0.0042 0.0133 0.0166
Echinococcus granulosus PHD finger protein rhinoceros 0.0068 0.0292 0.0336
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0655 0.0815
Trichomonas vaginalis fk506-binding protein, putative 0.0205 0.1133 0.307
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.003 0.0061 0.0031
Echinococcus granulosus dnaJ subfamily B 0.0398 0.2311 0.2854
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.0541 0.1705
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0039 0.0117 0.0199
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0205 0.1133 0.307
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0038 0.0106 0.0179
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0087 0.041 0.051
Loa Loa (eye worm) TK/EGFR protein kinase 0.0091 0.0431 0.0536
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.0541 0.052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0042 0.0133 0.0151
Loa Loa (eye worm) hypothetical protein 0.0076 0.0338 0.0421
Chlamydia trachomatis dehyroquinate synthase 0.0053 0.0202 0.2305
Echinococcus granulosus insulin receptor 0.0029 0.0055 0.0041
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Loa Loa (eye worm) helicase 0.0024 0.0025 0.0031
Mycobacterium ulcerans carboxylesterase, LipT 0.0225 0.1255 0.3955
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0083 0.0474
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.0541 0.0647
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0028 0.0049 0.007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.03 0.1713 0.408
Loa Loa (eye worm) LGC-31 protein 0.0078 0.0354 0.044
Brugia malayi CHD4 protein 0.003 0.0057 0.0071
Trichomonas vaginalis glutaminase, putative 0.0539 0.3174 0.8717
Mycobacterium ulcerans hypothetical protein 0.0109 0.0541 0.1705
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0025 0.0026
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0225 0.1255 0.2958
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0078 0.0354 0.0332
Loa Loa (eye worm) ACC-1 protein 0.0078 0.0354 0.044
Brugia malayi Carboxylesterase family protein 0.0225 0.1255 0.1561
Echinococcus multilocularis jumonji domain containing protein 0.0095 0.0455 0.0434
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0108 0.0236
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0124 0.0632 0.0786
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0085 0.0091
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0002 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0113 0.0569 0.0682
Leishmania major UDP-galactopyranose mutase 0.0034 0.0084 0.0477
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0202 0.036
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0474 0.059
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0242 0.0301
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Brugia malayi Carboxylesterase family protein 0.0225 0.1255 0.1561
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.1002 0.1234
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0137 0.0714 0.2249
Schistosoma mansoni hypothetical protein 0.0024 0.0025 0.0017
Schistosoma mansoni neuroligin 3 (S09 family) 0.0225 0.1255 0.1549
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0047 0.0163 0.0203
Onchocerca volvulus Putative nachr subunit 0.0078 0.0354 0.2672
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0541 0.1434
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0202 0.1152
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0303 0.1733 0.5459
Trichomonas vaginalis chromobox protein, putative 0.009 0.0427 0.1117
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0025 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0084 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0101 0.0216
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0085 0.0078
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0225 0.1255 0.2958
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0185
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0078 0.0354 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0101 0.0216
Echinococcus granulosus jumonji domain containing 1A 0.0181 0.0987 0.1203
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.1066
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0034 0.0084 0.0529
Schistosoma mansoni cpg binding protein 0.0065 0.0274 0.0327
Schistosoma mansoni importin beta-1 0.006 0.0241 0.0286
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0184 0.1002 0.1247
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0694 0.4129 1
Brugia malayi Protein kinase domain containing protein 0.0029 0.0055 0.0068
Brugia malayi Carboxylesterase family protein 0.1333 0.8042 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.4354
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0023 0.0131
Onchocerca volvulus 0.0028 0.0049 0.0191
Brugia malayi latrophilin 2 splice variant baaae 0.0245 0.1373 0.1708
Schistosoma mansoni jumonji domain containing protein 0.0181 0.0987 0.1214
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0085 0.0541
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0145 0.0764 0.0925
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0034 0.0084 0.0529
Echinococcus granulosus geminin 0.1213 0.7305 0.9082
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0365 0.2114 0.2097
Trypanosoma cruzi UDP-galactopyranose mutase 0.0034 0.0084 0.0477
Echinococcus granulosus lysine specific histone demethylase 1A 0.0034 0.0084 0.0077
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0145 0.0764 0.1752
Loa Loa (eye worm) hypothetical protein 0.1333 0.8042 1
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0269 0.1525 0.3618
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.003 0.0061 0.0158
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0078 0.0354 0.0332
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0172 0.0412
Mycobacterium leprae Probable lipase LipE 0.0109 0.0541 0.3016
Echinococcus multilocularis chromobox protein 1 0.0149 0.0789 0.0769
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0078 0.0354 0.0426
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0039 0.0117 0.0199
Echinococcus granulosus acetylcholinesterase 0.1333 0.8042 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0843 0.1048
Brugia malayi CXXC zinc finger family protein 0.006 0.0242 0.0301
Echinococcus granulosus lysine specific histone demethylase 1A 0.0087 0.041 0.0484
Brugia malayi RNA, U transporter 1 0.017 0.0915 0.1138
Loa Loa (eye worm) hypothetical protein 0.006 0.0241 0.03
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0034 0.0083 0.0166
Onchocerca volvulus 0.006 0.0242 0.1764
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0078 0.0354 0.044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0113 0.0569 0.0548
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0144 0.0267
Leishmania major hypothetical protein, unknown function 0.0039 0.0117 0.0664
Trichomonas vaginalis hypothetical protein 0.0024 0.0025 0.0006
Echinococcus multilocularis BC026374 protein (S09 family) 0.0225 0.1255 0.1236
Brugia malayi AF-10 protein 0.0022 0.0012 0.0014
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0225 0.1255 0.1236
Brugia malayi beta-lactamase 0.0109 0.0541 0.0673
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.1755 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.009 0.0186
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0205 0.1133 1
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0028 0.0049 0.0027
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Trichomonas vaginalis fk506 binding protein, putative 0.0028 0.0049 0.0071
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0134 0.0167
Mycobacterium tuberculosis Carboxylesterase LipT 0.0225 0.1255 0.2958
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0338 0.1807
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0205 0.1133 0.1409
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0036 0.0096 0.0074
Echinococcus multilocularis lysine specific demethylase 5A 0.0282 0.1601 0.1582
Brugia malayi Cation transporter family protein 0.0078 0.0354 0.044
Onchocerca volvulus 0.0078 0.0354 0.2672
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.0541 0.0673
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0113 0.0569 0.0707
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0637 0.3777 0.4697
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0541 0.3083
Loa Loa (eye worm) hypothetical protein 0.0066 0.0277 0.0345
Echinococcus granulosus cpg binding protein 0.0065 0.0274 0.0314
Echinococcus granulosus chromobox protein 1 0.0149 0.0789 0.0957
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0084 0.0086
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0225 0.1255 0.1549
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0048 0.0172 0.0186
Schistosoma mansoni nAChR subunit 0.0036 0.0096 0.0105
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0843 0.1048
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.0292 0.0529
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.0541 0.1208
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.009 0.0186
Trichomonas vaginalis chromobox protein, putative 0.0149 0.0789 0.212
Brugia malayi hypothetical protein 0.0034 0.0086 0.0107
Onchocerca volvulus 0.0093 0.0445 0.3413
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0109 0.0545 0.0664
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.009 0.0097
Brugia malayi jmjC domain containing protein 0.0098 0.0474 0.059
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0205 0.1133 0.6453
Echinococcus multilocularis nAChR subunit 0.0078 0.0354 0.0332
Schistosoma mansoni alpha-glucosidase 0.0136 0.0708 0.0867
Onchocerca volvulus 0.0225 0.1255 1
Loa Loa (eye worm) carboxylesterase 0.1333 0.8042 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0109 0.0545 0.0664
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0144 0.018
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0087 0.041 0.0389
Mycobacterium ulcerans lipase LipD 0.0109 0.0541 0.1705
Onchocerca volvulus 0.0091 0.0435 0.3331
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0083 0.0474
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0078 0.0354 0.0332
Loa Loa (eye worm) hypothetical protein 0.0068 0.0292 0.0363
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0029 0.0055 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Schistosoma mansoni inositol monophosphatase 0.0034 0.0083 0.0089
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0225 0.1255 0.3409
Trichomonas vaginalis immunophilin, putative 0.0205 0.1133 0.307
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0101 0.0216
Schistosoma mansoni phd/f-box containing protein 0.0098 0.0474 0.0576
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0025 0.0006
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0109 0.0545 0.0652
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Loa Loa (eye worm) TK/INSR protein kinase 0.0029 0.0055 0.0068
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.0388 0.2948
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0028 0.0049 0.006
Toxoplasma gondii HEAT repeat-containing protein 0.006 0.0241 0.0434
Loa Loa (eye worm) hypothetical protein 0.0135 0.07 0.087
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0205 0.1133 0.6453
Echinococcus multilocularis chromobox protein 1 0.0149 0.0789 0.0769
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0144 0.0123
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0035 0.0089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0085 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Echinococcus multilocularis inositol monophosphatase 1 0.0034 0.0083 0.0061
Brugia malayi jmjC domain containing protein 0.0098 0.0474 0.059
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Giardia lamblia PHD finger protein 15 0.0068 0.0292 0.0677
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0028 0.0049 0.007
Schistosoma mansoni hypothetical protein 0.0113 0.0569 0.0694
Schistosoma mansoni jumonji domain containing protein 0.032 0.1834 0.227
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0028 0.0049 0.0071
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0025 0.0003
Onchocerca volvulus 0.0225 0.1255 1
Echinococcus granulosus phd:f box containing protein 0.0098 0.0474 0.0564
Schistosoma mansoni jun-related protein 0.0039 0.0116 0.013
Onchocerca volvulus 0.0042 0.0133 0.0879
Onchocerca volvulus 0.0066 0.0277 0.2048
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.4354
Schistosoma mansoni nAChR subunit 0.0036 0.0096 0.0105
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0205 0.1133 0.1385
Brugia malayi Cation transporter family protein 0.0078 0.0354 0.044
Loa Loa (eye worm) acetylcholinesterase 1 0.1333 0.8042 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.0427 0.3264
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0036 0.0096 0.012
Giardia lamblia Fructose-bisphosphate aldolase 0.0614 0.3638 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0068 0.0292 0.0349
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0036 0.0096 0.0074
Echinococcus multilocularis JmjC domain containing protein 4 0.0098 0.0474 0.0453
Brugia malayi Inositol-1 0.0034 0.0083 0.0103
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0042 0.0133 0.0166
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0034 0.0079
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0084 0.0388 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0238 0.0595
Echinococcus granulosus snurportin 1 0.0637 0.3777 0.4682
Loa Loa (eye worm) latrophilin receptor protein 2 0.0113 0.0569 0.0707
Brugia malayi chromobox protein homolog 3 0.0084 0.0388 0.0482
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.1002 0.0983
Onchocerca volvulus 0.0109 0.0541 0.4195
Echinococcus multilocularis 0.0028 0.0046 0.0024
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.003 0.0057 0.0044
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0125 0.0644 0.1195
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0087 0.041 0.0497
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.1002 0.1234
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0184 0.1002 0.1247
Onchocerca volvulus 0.0078 0.0354 0.2672
Echinococcus multilocularis carboxylesterase 5A 0.1333 0.8042 0.8037
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0172 0.0412
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0096 0.012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0225 0.1255 0.1549
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0292 0.2406
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0438 0.0545
Loa Loa (eye worm) inositol-1 0.0034 0.0083 0.0103
Leishmania major hypothetical protein, conserved 0.0053 0.0202 0.1152
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0085 0.0484
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0474 0.059
Echinococcus granulosus chromobox protein 1 0.0149 0.0789 0.0957
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0205 0.1133 0.1396
Schistosoma mansoni chromodomain helicase DNA binding protein 0.003 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Schistosoma mansoni hypothetical protein 0.0113 0.0569 0.0694
Schistosoma mansoni glutaminase 0.0539 0.3174 0.3938
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Loa Loa (eye worm) hypothetical protein 0.0245 0.1373 0.1708
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0023 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.057 0.1056
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0023 0.0001
Brugia malayi beta-lactamase family protein 0.0109 0.0541 0.0673
Trichomonas vaginalis esterase, putative 0.0109 0.0541 0.1434
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0028 0.0049 0.006
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0028 0.0049 0.007
Loa Loa (eye worm) glutaminase 0.0539 0.3174 0.3947
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0096 0.012
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0078 0.0354 0.0332
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0023 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0023 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0202 0.1152
Brugia malayi PHD-finger family protein 0.0068 0.0292 0.0363
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0028 0.0049 0.006
Brugia malayi bZIP transcription factor family protein 0.0048 0.0172 0.0213
Entamoeba histolytica hypothetical protein 0.0024 0.0025 0.0006
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0078 0.0354 0.0426
Brugia malayi jmjC domain containing protein 0.0334 0.1924 0.2393
Echinococcus granulosus inositol monophosphatase 1 0.0034 0.0083 0.0076
Onchocerca volvulus 0.0078 0.0354 0.2672
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.014 0.0797
Echinococcus granulosus neuroligin 0.0225 0.1255 0.1538
Trichomonas vaginalis chromobox protein, putative 0.009 0.0427 0.1117
Schistosoma mansoni tyrosine kinase 0.0029 0.0055 0.0054
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0205 0.1133 0.1385
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0078 0.0354 0.044
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0109 0.0545 0.0664
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0039 0.0117 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0025 0.0017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0078 0.0354 0.0426
Toxoplasma gondii melibiase subfamily protein 0.0109 0.0545 0.1007
Loa Loa (eye worm) hypothetical protein 0.0177 0.096 0.1193
Loa Loa (eye worm) PHD-finger family protein 0.0068 0.0292 0.0363
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0765 0.4359
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0084 0.0104
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0037 0.0103 0.0113
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0145 0.0764 0.2406
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Onchocerca volvulus 0.0028 0.0049 0.0191
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Schistosoma mansoni NADH dehydrogenase subunit 1 0.0039 0.0115 0.0128
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0078 0.0354 0.044
Echinococcus multilocularis snurportin 1 0.0637 0.3777 0.3763
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0137 0.0714 0.1327
Brugia malayi prolyl 4-hydroxylase 2 precursor 0.0026 0.0036 0.0045
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0144 0.1078
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Echinococcus granulosus BC026374 protein S09 family 0.0225 0.1255 0.1538
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0192 0.1053 0.131
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0358 0.2066 0.257
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0144 0.1078
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0124 0.0632 0.0612
Echinococcus multilocularis chromobox protein 2 0.0024 0.0025 0.0003
Toxoplasma gondii PLU-1 family protein 0.0048 0.0167 0.0294
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0078 0.0354 0.0414
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0039 0.0117 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0541 0.1434
Trichomonas vaginalis ran, putative 0.0044 0.0144 0.0336
Entamoeba histolytica hypothetical protein 0.0048 0.0172 0.0412
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0541 0.1434
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Loa Loa (eye worm) jmjC domain-containing protein 0.0334 0.1924 0.2393
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0078 0.0354 0.0414
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.009 0.0186
Schistosoma mansoni alpha glucosidase 0.0035 0.009 0.0098
Trypanosoma cruzi UDP-galactopyranose mutase 0.0034 0.0084 0.0477
Brugia malayi hypothetical protein 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0098 0.0474 0.059
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0053 0.0202 0.0995
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0137 0.0714 0.4046
Brugia malayi glutaminase DH11.1 0.0539 0.3174 0.3947
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.1002 0.1234
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0108 0.0236
Loa Loa (eye worm) hypothetical protein 0.1333 0.8042 1
Brugia malayi prolyl 4-hydroxylase 0.0124 0.0632 0.0786
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0028 0.0049 0.0277
Echinococcus multilocularis glycine receptor subunit beta 0.0078 0.0354 0.0332
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0144 0.0153
Echinococcus granulosus JmjC domain containing protein 4 0.0098 0.0474 0.0564
Schistosoma mansoni chromobox protein 0.0024 0.0025 0.0017
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.009 0.0186
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.0541 0.1208
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.1755 1
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0205 0.1133 0.3021
Loa Loa (eye worm) CHromoDomain protein family member 0.003 0.0057 0.0071
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0025 0.0017
Entamoeba histolytica hypothetical protein 0.0042 0.0133 0.0305
Brugia malayi Importin beta-1 subunit 0.006 0.0241 0.03
Echinococcus multilocularis GPCR, family 2 0.0113 0.0569 0.0548
Echinococcus granulosus glycine receptor subunit alpha 1 0.0078 0.0354 0.0414
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Echinococcus multilocularis nAChR subunit 0.0042 0.0133 0.0111
Chlamydia trachomatis protoporphyrinogen oxidase 0.0034 0.0084 0.0529
Schistosoma mansoni tyrosine kinase 0.0091 0.0431 0.0522
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0025 0.0006
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0036 0.0096 0.0092
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0039 0.0117 0.0664
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0205 0.1133 0.1409
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0078 0.0354 0.0332
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0205 0.1133 0.6453
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0093 0.0445 0.0553
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0037 0.0101 0.0216
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.009 0.0186
Mycobacterium tuberculosis Conserved protein 0.0109 0.0541 0.1208
Schistosoma mansoni hypothetical protein 0.0113 0.0569 0.0694
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0026 0.0033 0.0027
Onchocerca volvulus 0.0225 0.1255 1
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0084 0.0388 0.0979
Brugia malayi PHD-finger family protein 0.0027 0.0043 0.0054
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0023 0.0131
Leishmania major hypothetical protein, conserved 0.0039 0.0117 0.0664
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0113 0.0569 0.0682
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.2311 0.2294
Echinococcus multilocularis Chromo domain 0.0024 0.0025 0.0003
Loa Loa (eye worm) carboxylesterase 0.0225 0.1255 0.1561
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0078 0.0354 0.044
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0028 0.0049 0.006
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0205 0.1133 0.6453
Loa Loa (eye worm) hypothetical protein 0.0034 0.0084 0.0104
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0085 0.0106
Toxoplasma gondii hypothetical protein 0.0028 0.0045 0.0064
Brugia malayi Latrophilin receptor protein 2 0.0113 0.0569 0.0707
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.009 0.0514
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.009 0.0514
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.1002 0.1222
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0039 0.0117 0.0664
Echinococcus multilocularis epidermal growth factor receptor 0.0091 0.0431 0.041
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0042 0.0133 0.0151
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0042 0.0133 0.0166
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0085 0.0139
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0028 0.0049 0.0277
Mycobacterium leprae conserved hypothetical protein 0.0109 0.0541 0.3016
Schistosoma mansoni tyrosine kinase 0.0048 0.0169 0.0196
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.0541 0.1208
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0049 0.0071
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0078 0.0354 0.0414
Schistosoma mansoni immunophilin 0.0205 0.1133 0.1396
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0025 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0025 0.0006
Brugia malayi NADH dehydrogenase subunit 1 0.0039 0.0115 0.0142
Echinococcus multilocularis insulin receptor 0.0029 0.0055 0.0033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Loa Loa (eye worm) acetylcholine receptor protein 0.0036 0.0096 0.012
Brugia malayi isocitrate dehydrogenase 0.0034 0.0085 0.0106
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0039 0.0117 0.0199
Schistosoma mansoni chromobox protein 0.0149 0.0789 0.0969
Schistosoma mansoni immunophilin 0.0177 0.096 0.1181
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Onchocerca volvulus 0.0042 0.0133 0.0879
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0202 0.1599
Schistosoma mansoni tyrosine kinase 0.0048 0.0169 0.0196
Schistosoma mansoni 3-dehydroquinate synthase 0.0053 0.0202 0.0237
Plasmodium falciparum phd finger protein, putative 0.0068 0.0292 0.2406
Schistosoma mansoni cpg binding protein 0.006 0.0242 0.0287
Loa Loa (eye worm) hypothetical protein 0.0358 0.2066 0.257
Schistosoma mansoni ran 0.0044 0.0144 0.0166
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0078 0.0354 0.044
Leishmania major importin beta-1 subunit, putative 0.0048 0.0172 0.0979
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0034 0.0079
Schistosoma mansoni cpg binding protein 0.0065 0.0274 0.0327
Echinococcus granulosus neuropeptide receptor A26 0.0979 0.5871 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0388 0.1009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.0541 0.0673
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0085 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.009 0.0186
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0241 0.1373
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Schistosoma mansoni nAChR subunit 0.0078 0.0354 0.0426
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.1755 1
Brugia malayi Carboxylesterase family protein 0.1333 0.8042 1
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.009 0.0084
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0177 0.096 0.1169
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0179 0.0319
Schistosoma mansoni tyrosine kinase 0.0049 0.0175 0.0204
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.0541 0.1208
Onchocerca volvulus 0.0078 0.0354 0.2672
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0034 0.0084 0.0529
Brugia malayi amine oxidase, flavin-containing family protein 0.004 0.0118 0.0147
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0358 0.2066 0.257
Trypanosoma brucei glucosidase, putative 0.0035 0.009 0.0514
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0083 0.0474
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0078 0.0354 0.044
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0365 0.2114 0.2609
Echinococcus granulosus peregrin 0.0068 0.0292 0.0336
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.009 0.0186
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.009 0.0112
Toxoplasma gondii ABC1 family protein 0.0109 0.0541 0.1001
Entamoeba histolytica hypothetical protein, conserved 0.0037 0.0101 0.0216
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0179 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.0039 0.0115 0.0142
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0198 0.1126
Brugia malayi hypothetical protein 0.0035 0.009 0.0112
Schistosoma mansoni hypothetical protein 0.0039 0.0116 0.013
Echinococcus granulosus nAChR subunit 0.0078 0.0354 0.0414
Echinococcus granulosus epidermal growth factor receptor 0.0049 0.0175 0.0191
Echinococcus granulosus acetylcholinesterase 0.1333 0.8042 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0078 0.0354 0.0414
Mycobacterium ulcerans glutaminase 0.0539 0.3174 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0109 0.0545 0.0664
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0205 0.1133 0.1409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0202 0.0251
Onchocerca volvulus 0.0225 0.1255 1
Schistosoma mansoni acetylcholine receptor subunit beta 0.0036 0.0096 0.0105
Onchocerca volvulus Tyrosine kinase homolog 0.0086 0.0401 0.3059
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0078 0.0354 0.0332
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0031
Echinococcus multilocularis importin subunit beta 1 0.006 0.0241 0.0219
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0541 0.066
Brugia malayi hypothetical protein 0.0034 0.0084 0.0104
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0078 0.0354 0.0426
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0212
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0843 0.1023
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0238 0.0595
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0025 0.0006
Onchocerca volvulus 0.0036 0.0096 0.0578
Mycobacterium ulcerans dehydrogenase 0.0034 0.0084 0.0264
Leishmania major peptidylprolyl isomerase-like protein 0.0205 0.1133 0.6453
Leishmania major hypothetical protein, conserved 0.0109 0.0541 0.3083
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0071
Brugia malayi jmjC domain containing protein 0.0181 0.0987 0.1227
Schistosoma mansoni acetylcholine receptor-related 0.0036 0.0096 0.0105
Schistosoma mansoni hypothetical protein 0.0068 0.0292 0.0349
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0036 0.0096 0.012
Mycobacterium ulcerans hypothetical protein 0.0162 0.0866 0.2727
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0338 0.0394
Echinococcus multilocularis peregrin 0.0068 0.0292 0.027
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.009 0.0085
Echinococcus granulosus epidermal growth factor receptor 0.0091 0.0431 0.051
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Schistosoma mansoni BC026374 protein (S09 family) 0.0225 0.1255 0.1549
Mycobacterium tuberculosis Conserved protein 0.0109 0.0541 0.1208
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0354 0.044
Brugia malayi Melibiase family protein 0.0073 0.0322 0.04
Mycobacterium tuberculosis Possible formate hydrogenlyase HycD (FHL) 0.0039 0.0115 0.0162
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0085 0.0484
Loa Loa (eye worm) hypothetical protein 0.0109 0.0541 0.0673
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0202 0.1116 0.1364
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0025 0.0003
Brugia malayi Protein cec-1. 0.0024 0.0025 0.0031
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0034 0.0084 0.009
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0085 0.0139
Echinococcus multilocularis glycine receptor subunit beta 0.0078 0.0354 0.0332
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0083 0.0166
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0025 0.0026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0113 0.0569 0.0548
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0025 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0118 0.0147
Onchocerca volvulus 0.0038 0.0108 0.0673
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0614 0.3638 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0765 0.4359
Echinococcus granulosus glycine receptor subunit beta 0.0078 0.0354 0.0414
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0025 0.0026
Brugia malayi SWIRM domain containing protein 0.0093 0.0445 0.0553
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0092 0.0438 0.0545
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0042 0.0133 0.0166
Schistosoma mansoni alpha-glucosidase 0.0136 0.0708 0.0867
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0085 0.0063
Schistosoma mansoni immunophilin 0.0205 0.1133 0.1396
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0028 0.0049 0.0277
Schistosoma mansoni hypothetical protein 0.0113 0.0569 0.0694
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0025 0.0006
Schistosoma mansoni hypothetical protein 0.0145 0.0764 0.0936
Trichomonas vaginalis chromobox protein, putative 0.0149 0.0789 0.212
Loa Loa (eye worm) jmjC domain-containing protein 0.0181 0.0987 0.1227
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0338 0.0617
Loa Loa (eye worm) hypothetical protein 0.0073 0.0322 0.04
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.009 0.0186
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0205 0.1133 0.307
Echinococcus granulosus glycine receptor subunit alpha 1 0.0078 0.0354 0.0414
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0084 0.0529
Loa Loa (eye worm) hypothetical protein 0.03 0.1713 0.213
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0843 0.0823
Mycobacterium tuberculosis Conserved protein 0.0109 0.0541 0.1208
Loa Loa (eye worm) hypothetical protein 0.0225 0.1255 0.1561
Treponema pallidum fructose-bisphosphate aldolase 0.0614 0.3638 1
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0205 0.1133 0.6453
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0614 0.3638 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0078 0.0354 0.0414
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.0541 0.1208
Schistosoma mansoni acetylcholinesterase 0.0225 0.1255 0.1549
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0084 0.0388 0.5095
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0541 0.1434
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0205 0.1133 0.307
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0166
Brugia malayi hypothetical protein 0.0036 0.0096 0.012
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0205 0.1133 0.3021
Entamoeba histolytica hypothetical protein 0.0024 0.0025 0.0006
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0098 0.0474 0.2702
Echinococcus multilocularis 0.0034 0.0084 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0614 0.3638 1
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0078 0.0354 0.0414
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.1066
Trichomonas vaginalis fk506-binding protein, putative 0.0028 0.0049 0.0071
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0109 0.0545 0.0524
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0034 0.0083 0.0262
Echinococcus multilocularis phd:f box containing protein 0.0098 0.0474 0.0453
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0866 0.2003
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0202 0.1599
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0064 0.0112
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0338 0.2827
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0185
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0048 0.0172 0.015
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0053 0.0202 0.0376
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0035 0.0089
Brugia malayi hypothetical protein 0.0036 0.0096 0.012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0085 0.0063
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0303 0.1733 0.5459
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0098 0.0474 0.2702
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0202 0.1152
Echinococcus granulosus jumonji domain containing protein 0.0095 0.0455 0.0539
Loa Loa (eye worm) heterochromatin protein 1 0.0149 0.0789 0.0982
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0338 0.4052
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0085 0.0484
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0205 0.1133 0.1113
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0073 0.0322 0.0826
Echinococcus granulosus para nitrobenzyl esterase 0.0225 0.1255 0.1538
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0028 0.0049 0.007
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0338 0.0317
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0028 0.0049 0.0081
Echinococcus granulosus importin subunit beta 1 0.006 0.0241 0.0273
Loa Loa (eye worm) hypothetical protein 0.0078 0.0354 0.044
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0034 0.0084 0.0291
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0085 0.0484
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.0541 0.1208
Leishmania major GTP-binding protein, putative 0.0044 0.0144 0.0823
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.009 0.0068
Echinococcus granulosus neuropeptide s receptor 0.0979 0.5871 0.7294
Loa Loa (eye worm) FKBP5 protein 0.0205 0.1133 0.1409
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0144 0.0251
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.009 0.0186
Plasmodium vivax importin-beta 2, putative 0.006 0.0241 0.1949
Schistosoma mansoni tyrosine kinase 0.0048 0.0169 0.0196
Mycobacterium ulcerans oxidoreductase 0.0034 0.0084 0.0264
Echinococcus multilocularis neuropeptide s receptor 0.0979 0.5871 0.5862
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0765 0.4359
Loa Loa (eye worm) hypothetical protein 0.0036 0.0096 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0108 0.0236
Onchocerca volvulus 0.0039 0.0115 0.0727
Onchocerca volvulus Alhambra homolog 0.0068 0.0292 0.2167
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0078 0.0354 0.044
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0338 0.0407
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0078 0.0354 0.044
Mycobacterium ulcerans monoamine oxidase 0.0034 0.0084 0.0264
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0124 0.0632 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.007 0.0129
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0541 0.1434

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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