Detailed information for compound 1246144

Basic information

Technical information
  • TDR Targets ID: 1246144
  • Name: 1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethy l)oxolan-2-yl]pyrimidine-2,4-dione
  • MW: 248.184 | Formula: C9H10F2N2O4
  • H donors: 2 H acceptors: 3 LogP: -0.8 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1F)F)n1ccc(=O)[nH]c1=O
  • InChi: 1S/C9H10F2N2O4/c10-6-4(3-14)17-8(7(6)11)13-2-1-5(15)12-9(13)16/h1-2,4,6-8,14H,3H2,(H,12,15,16)/t4-,6-,7-,8-/m1/s1
  • InChiKey: ZACSMWVJEMXZMV-XVFCMESISA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
  • 1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethyl)-2-tetrahydrofuranyl]pyrimidine-2,4-dione
  • 1-[(2R,3S,4R,5R)-3,4-difluoro-5-methylol-tetrahydrofuran-2-yl]pyrimidine-2,4-quinone
  • 127840-99-7
  • 2',3'-Difluoro-2',3'-dideoxyuridine
  • 2',3'-F2-ddU
  • AIDS-001170
  • AIDS001170
  • Uridine, 2',3'-dideoxy-2',3'-difluoro-
  • NSC 646939

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus sex peptide receptor 0.0056 0.0109 0.0109
Giardia lamblia DINP protein human, muc B family 0.0023 0.0004 0.0031
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Toxoplasma gondii aminopeptidase N, putative 0.0165 0.0464 1
Echinococcus granulosus neuropeptides capa receptor 0.0056 0.0109 0.0109
Echinococcus granulosus metabotropic glutamate receptor 2 0.0096 0.0239 0.0239
Echinococcus granulosus fmrfamide receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0244 0.0717 0.0717
Onchocerca volvulus 0.0056 0.0109 0.1265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0045 0.0045
Brugia malayi Peptidase family M1 containing protein 0.0165 0.0464 0.1017
Onchocerca volvulus 0.0056 0.0109 0.1265
Echinococcus multilocularis neuropeptide Y receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.034
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0056 0.0109 0.0109
Schistosoma mansoni amine GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni histamine h1 receptor 0.0056 0.0109 0.0109
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus aminopeptidase N 0.0165 0.0464 0.0464
Schistosoma mansoni alpha-1 adrenergic receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.0086 0.0086
Loa Loa (eye worm) TYRA-2 protein 0.0056 0.0109 0.0108
Echinococcus granulosus neuropeptide receptor A26 0.0603 0.1878 0.1878
Loa Loa (eye worm) hypothetical protein 0.0165 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Onchocerca volvulus 0.0056 0.0109 0.1265
Schistosoma mansoni DNA polymerase eta 0.0023 0.0004 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0056 0.0109 0.0109
Echinococcus granulosus 7TM GPCR rhodopsin 0.0056 0.0109 0.0109
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0165 0.0464 0.0464
Echinococcus granulosus RUN 0.0023 0.0005 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0056 0.0109 0.0109
Schistosoma mansoni opsin-like receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Brugia malayi Metabotropic glutamate receptor precursor. 0.0114 0.0299 0.0654
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Schistosoma mansoni biogenic amine receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0046 0.0464
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0056 0.0109 0.0238
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0103
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0004 0.0004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Leishmania major hypothetical protein, conserved 0.0036 0.0046 0.0984
Schistosoma mansoni chromobox protein 0.0082 0.0193 0.0193
Mycobacterium ulcerans aminopeptidase N PepN 0.0165 0.0464 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Mycobacterium ulcerans aminopeptidase N PepN 0.0165 0.0464 1
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0029 0.0024 0.0023
Echinococcus granulosus biogenic amine 5HT receptor 0.0056 0.0109 0.0109
Brugia malayi RE15519p 0.0056 0.0109 0.0238
Echinococcus multilocularis fmrfamide receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0056 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Onchocerca volvulus 0.0056 0.0109 0.1265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni neuropeptide receptor 0.0056 0.0109 0.0109
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Onchocerca volvulus 0.0277 0.0826 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.0056 0.0109 0.0109
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0088 0.0894
Brugia malayi sulfakinin receptor protein 0.0056 0.0109 0.0238
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0029 0.0024 0.0023
Loa Loa (eye worm) peptidase family M1 containing protein 0.0165 0.0464 0.0464
Brugia malayi AKH receptor 0.0056 0.0109 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0005 0.0099
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0046 0.0984
Schistosoma mansoni neuropeptide receptor 0.0056 0.0109 0.0109
Schistosoma mansoni metabotropic glutamate receptor 0.0096 0.0239 0.0239
Brugia malayi Peptidase family M1 containing protein 0.0165 0.0464 0.1017
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0056 0.0109 0.0109
Brugia malayi Melatonin receptor type 1A 0.0056 0.0109 0.0238
Echinococcus multilocularis neuropeptide receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.014 0.0383 0.0383
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0165 0.0464 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0056 0.0109 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0109 0.0109
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0046 0.0676
Trypanosoma brucei unspecified product 0.0023 0.0004 0.0065
Brugia malayi ORL1-like opioid receptor 0.0056 0.0109 0.0238
Brugia malayi PHD-finger family protein 0.0028 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0141 0.0384 0.0383
Echinococcus granulosus neuropeptide s receptor 0.0603 0.1878 0.1878
Echinococcus multilocularis dna polymerase eta 0.0023 0.0004 0.0004
Echinococcus granulosus g protein coupled receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi Dopamine receptor 0.0056 0.0109 0.0238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0046 0.0676
Echinococcus granulosus neuropeptide Y receptor 0.0056 0.0109 0.0109
Brugia malayi putative neuropeptide receptor NPR1 0.0056 0.0109 0.0238
Loa Loa (eye worm) glutamate receptor 0.0114 0.0299 0.0298
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0104 0.0104
Echinococcus multilocularis aminopeptidase N 0.0165 0.0464 0.0464
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0046 0.0676
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0004 0.0065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0046 0.0676
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0056 0.0109 0.1265
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0056 0.0109 0.0238
Brugia malayi G-protein coupled receptor 0.0056 0.0109 0.0238
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0073 0.0073
Onchocerca volvulus 0.0056 0.0109 0.1265
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0165 0.0464 0.4716
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) beta-lactamase 0.0036 0.0046 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0036 0.0046 0.05
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0046 0.01
Schistosoma mansoni amine GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.0193 0.0193
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0159 0.0445 1
Brugia malayi Serotonin receptor 0.0056 0.0109 0.0238
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0056 0.0109 0.0109
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0165 0.0464 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0056 0.0109 0.0238
Echinococcus granulosus neuropeptide receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0145 0.0145
Schistosoma mansoni neuropeptide F-like receptor 0.0056 0.0109 0.0109
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0165 0.0464 1
Brugia malayi larval opioid receptor 0.0056 0.0109 0.0238
Schistosoma mansoni growth hormone secretagogue receptor 0.0056 0.0109 0.0109
Echinococcus granulosus neuropeptide receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0165 0.0464 0.4716
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Schistosoma mansoni aminopeptidase A (M01 family) 0.0165 0.0464 0.0464
Brugia malayi Heterochromatin protein 1 0.0082 0.0193 0.0422
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0056 0.0109 0.0109
Trypanosoma cruzi aminopeptidase, putative 0.0165 0.0464 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi Pre-SET motif family protein 0.0035 0.0042 0.0092
Brugia malayi beta-lactamase family protein 0.0036 0.0046 0.01
Echinococcus granulosus g protein coupled receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis serotonin receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis G-protein coupled receptor, putative 0.0056 0.0109 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0046 0.0984
Echinococcus multilocularis G protein coupled receptor 139 0.0056 0.0109 0.0109
Brugia malayi metabotropic glutamate receptor type 2 0.0056 0.0109 0.0239
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0005 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0165 0.0464 0.5593
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Brugia malayi hypothetical protein 0.0023 0.0005 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0046 0.0464
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0056 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0005
Brugia malayi G protein-coupled receptor F59B2.13 0.0056 0.0109 0.0238
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0046 0.0984
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0056 0.0109 0.0108
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0045 0.0076 0.0076
Mycobacterium ulcerans lipase LipD 0.0036 0.0046 0.0984
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Onchocerca volvulus 0.0056 0.0109 0.1265
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.0984 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0001 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Treponema pallidum fructose-bisphosphate aldolase 0.0326 0.0984 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus orexin receptor type 2 0.0056 0.0109 0.0109
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0004 0.0065
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0046 0.0046
Brugia malayi Bromodomain containing protein 0.0084 0.02 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0042 0.0042
Brugia malayi neuropeptide F receptor 0.0056 0.0109 0.0238
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.0984 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0077
Echinococcus granulosus dna polymerase kappa 0.0023 0.0004 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0004 0.0065
Toxoplasma gondii aminopeptidase n, putative 0.0165 0.0464 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0005 0.0099
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Loa Loa (eye worm) glutamate receptor 0.0045 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Echinococcus granulosus somatostatin receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0109 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Echinococcus granulosus serotonin receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0165 0.0464 0.4716
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0056 0.0109 0.0109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0109 0.0109
Echinococcus granulosus tachykinin peptides receptor 99D 0.0056 0.0109 0.0109
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0004 0.0007
Brugia malayi hypothetical protein 0.0023 0.0005 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0329 0.0994 0.0993
Brugia malayi TATA binding protein associated factor 0.0165 0.0464 0.1017
Onchocerca volvulus 0.0036 0.0046 0.05
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0073 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.1432 0.4559 1
Brugia malayi Doublecortin family protein 0.0023 0.0005 0.001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0104 0.0104
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0004 0.0003
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0038 0.0038
Toxoplasma gondii aminopeptidase N protein 0.0165 0.0464 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.0779
Loa Loa (eye worm) aminopeptidase N 0.0165 0.0464 0.0464
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0011 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0046 0.0984
Echinococcus multilocularis g-protein coupled receptor 0.0056 0.0109 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0088 0.1014
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus multilocularis fmrfamide receptor 0.0056 0.0109 0.0109
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0036 0.0046 0.05
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0056 0.0109 0.0108
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0004 0.0044
Mycobacterium ulcerans hypothetical protein 0.0036 0.0046 0.0984
Brugia malayi Tachykinin-like peptides receptor 99D 0.0056 0.0109 0.0238
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0004 0.0004
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0103 0.0264 0.0578
Loa Loa (eye worm) hypothetical protein 0.0165 0.0464 0.0464
Echinococcus multilocularis serotonin receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Schistosoma mansoni metabotropic glutamate receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Brugia malayi Bromodomain containing protein 0.0043 0.0068 0.0147
Schistosoma mansoni hypothetical protein 0.0056 0.0109 0.0109
Brugia malayi putative neuropeptide receptor 0.0056 0.0109 0.0238
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0056 0.0109 0.0109
Echinococcus granulosus dna polymerase eta 0.0023 0.0004 0.0004
Schistosoma mansoni myosin xvIII 0.0056 0.0109 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0056 0.0109 0.0108
Mycobacterium ulcerans beta-lactamase 0.0036 0.0046 0.0984
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0056 0.0109 0.0108
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Giardia lamblia Fructose-bisphosphate aldolase 0.0326 0.0984 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus multilocularis neuropeptide Y receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Schistosoma mansoni rab6-interacting 0.0023 0.0005 0.0005
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0096 0.0239 0.0239
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0046 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0165 0.0464 0.0464
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0023
Schistosoma mansoni hypothetical protein 0.0023 0.0004 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0165 0.0464 0.5593
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0004 0.0065
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0165 0.0464 1
Onchocerca volvulus 0.0056 0.0109 0.1265
Trypanosoma brucei Aminopeptidase M1, putative 0.0165 0.0464 1
Schistosoma mansoni ap endonuclease 0.0022 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0104 0.0104
Echinococcus multilocularis somatostatin receptor 0.0056 0.0109 0.0109
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0042 0.0902
Onchocerca volvulus 0.0056 0.0109 0.1265
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0193 0.1958
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0056 0.0109 0.0109
Schistosoma mansoni rab6-interacting 0.0023 0.0005 0.0005
Leishmania major DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Brugia malayi G-protein coupled receptor 0.0056 0.0109 0.0238
Loa Loa (eye worm) G-protein coupled receptor 0.0056 0.0109 0.0108
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0056 0.0109 0.0109
Entamoeba histolytica aminopeptidase, putative 0.0165 0.0464 0.4716
Schistosoma mansoni amine GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni polycystin 1-related 0.0023 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0165 0.0464 0.0464
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Brugia malayi Dopamine receptor protein 2 0.0056 0.0109 0.0238
Onchocerca volvulus 0.0048 0.0086 0.0979
Loa Loa (eye worm) hypothetical protein 0.0079 0.0185 0.0184
Echinococcus multilocularis neuropeptide receptor 0.0056 0.0109 0.0109
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0159 0.0445 0.6575
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0004 0.0065
Echinococcus multilocularis leukotriene A 4 hydrolase 0.3115 1 1
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0046 0.0676
Mycobacterium tuberculosis Conserved protein 0.0036 0.0046 0.0676
Schistosoma mansoni adenoreceptor 0.0056 0.0109 0.0109
Plasmodium vivax SET domain protein, putative 0.0035 0.0042 0.0902
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0004 0.0004
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0004 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0073 0.0073
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0056 0.0109 0.0109
Trypanosoma brucei Aminopeptidase M1, putative 0.0165 0.0464 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Echinococcus granulosus neuropeptides capa receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) TATA binding protein associated factor 0.0165 0.0464 0.0464
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0104 0.0104
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Brugia malayi neuropeptide F receptor 0.0056 0.0109 0.0238
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0073 0.0073
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0073 0.0073
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0004 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0046 0.0984
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0165 0.0464 1
Onchocerca volvulus 0.0056 0.0109 0.1265
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0145 0.0145
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0004 0.0007
Brugia malayi follicle stimulating hormone receptor 0.0329 0.0994 0.2178
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0046 0.0676
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Echinococcus granulosus dro:myosuppressin receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis orexin receptor type 2 0.0056 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Schistosoma mansoni neuropeptide receptor 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0056 0.0109 0.1265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Schistosoma mansoni biogenic amine receptor 0.0056 0.0109 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0046 0.0984
Brugia malayi Peptidase family M1 containing protein 0.0165 0.0464 0.1017
Echinococcus multilocularis chromobox protein 1 0.0082 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Onchocerca volvulus Neuropeptide F receptor homolog 0.0056 0.0109 0.1265
Schistosoma mansoni lipoxygenase 0.0098 0.0246 0.0246
Brugia malayi hypothetical protein 0.0165 0.0464 0.1017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Echinococcus granulosus G protein coupled receptor 139 0.0056 0.0109 0.0109
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0004 0.0031
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0165 0.0464 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0056 0.0109 0.0109
Schistosoma mansoni loxhd1 0.0023 0.0005 0.0005
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0046 0.0464
Onchocerca volvulus 0.0165 0.0464 0.5593
Echinococcus multilocularis neuropeptide s receptor 0.0603 0.1878 0.1878
Onchocerca volvulus 0.0056 0.0109 0.1265
Brugia malayi hypothetical protein 0.0165 0.0464 0.1017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0165 0.0464 1
Toxoplasma gondii ABC1 family protein 0.0036 0.0046 0.0984
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Trichomonas vaginalis set domain proteins, putative 0.0277 0.0826 0.8395
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0004 0.0044
Loa Loa (eye worm) melatonin receptor type 1A 0.0056 0.0109 0.0108
Brugia malayi beta-lactamase family protein 0.0036 0.0046 0.01
Mycobacterium tuberculosis Conserved protein 0.0036 0.0046 0.0676
Echinococcus granulosus arachidonate 5 lipoxygenase 0.014 0.0383 0.0383
Echinococcus granulosus hypothetical protein 0.0056 0.0109 0.0109
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0165 0.0464 1
Trypanosoma cruzi Aminopeptidase M1, putative 0.0165 0.0464 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Trypanosoma cruzi aminopeptidase, putative 0.0165 0.0464 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0046 0.0676
Leishmania major DNA polymerase eta, putative 0.0023 0.0004 0.0065
Echinococcus multilocularis neuropeptides capa receptor 0.0056 0.0109 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Brugia malayi GnHR receptor homolog 0.0056 0.0109 0.0238
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.3115 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0073 0.0072
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0141 0.0384 0.0384
Schistosoma mansoni biogenic amine (5HT) receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0109 0.0109
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0005 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0073 0.0158
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0024 0.0051
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0165 0.0464 0.0464
Echinococcus multilocularis sex peptide receptor 0.0056 0.0109 0.0109
Echinococcus granulosus chromobox protein 1 0.0082 0.0193 0.0193
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0109 0.0109
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Echinococcus multilocularis RUN 0.0023 0.0005 0.0005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.0676 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0109 0.0109
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0077 0.0878
Loa Loa (eye worm) G-protein coupled receptor 0.0056 0.0109 0.0108
Schistosoma mansoni hypothetical protein 0.0056 0.0109 0.0109
Schistosoma mansoni opsin-like receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.0779
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0165 0.0464 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0046 0.0046
Schistosoma mansoni chromobox protein 0.0082 0.0193 0.0193
Echinococcus granulosus 7tm_1 domain containing protein 0.0056 0.0109 0.0109
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0056 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0056 0.0109 0.0109
Schistosoma mansoni bromodomain containing protein 0.0071 0.0158 0.0158
Echinococcus granulosus chromobox protein 1 0.0082 0.0193 0.0193
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0011 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0046 0.0464
Schistosoma mansoni amine GPCR 0.0056 0.0109 0.0109
Echinococcus multilocularis dro:myosuppressin receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0056 0.0109 0.0109
Brugia malayi Dopamine receptor protein 1 0.0056 0.0109 0.0238
Onchocerca volvulus 0.0056 0.0109 0.1265
Loa Loa (eye worm) leukotriene A4 hydrolase 0.3115 1 1
Echinococcus multilocularis chromobox protein 1 0.0082 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0043 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0056 0.0109 0.0109
Echinococcus multilocularis neuropeptides capa receptor 0.0056 0.0109 0.0109
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0056 0.0109 0.0238
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Echinococcus granulosus neuropeptide FF receptor 2 0.0056 0.0109 0.0109
Echinococcus granulosus allatostatin A receptor 0.0056 0.0109 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0056 0.0109 0.1265
Echinococcus multilocularis neuropeptide receptor A26 0.0603 0.1878 0.1878
Brugia malayi beta-lactamase 0.0036 0.0046 0.01
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0056 0.0109 0.0109
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0159 0.0445 0.9573
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0046 0.0046
Onchocerca volvulus 0.0036 0.0045 0.0488
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0109 0.0109
Onchocerca volvulus 0.0056 0.0109 0.1265
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.0984 1
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.013 0.0349 0.0349
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Echinococcus granulosus g-protein coupled receptor 0.0056 0.0109 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0004 0.0065
Schistosoma mansoni opsin-like receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0193 0.1958
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0165 0.0464 0.0464
Onchocerca volvulus 0.0056 0.0109 0.1265
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.034
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi Pre-SET motif family protein 0.0244 0.0717 0.1572
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0109 0.0109
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0109 0.0109
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0005 0.0005
Trypanosoma brucei aminopeptidase, putative 0.0165 0.0464 1
Brugia malayi chromobox protein homolog 3 0.0046 0.0077 0.0168
Onchocerca volvulus 0.0056 0.0109 0.1265
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0165 0.0464 1
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0056 0.0109 0.0238
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0165 0.0464 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0046 0.0046
Mycobacterium tuberculosis Conserved protein 0.0036 0.0046 0.0676
Schistosoma mansoni lipoxygenase 0.014 0.0383 0.0383
Schistosoma mansoni neuropeptide f receptor 76f 0.0056 0.0109 0.0109
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Schistosoma mansoni amine GPCR 0.0056 0.0109 0.0109
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0165 0.0464 1
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0109 0.0109
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0005 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0046 0.0464
Echinococcus multilocularis allatostatin A receptor 0.0056 0.0109 0.0109
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0059 0.0059
Brugia malayi Serotonin receptor 0.0056 0.0109 0.0238
Echinococcus granulosus g protein coupled receptor 0.0056 0.0109 0.0109
Brugia malayi G protein-coupled receptor 0.0056 0.0109 0.0238
Echinococcus granulosus neuropeptide Y receptor 0.0056 0.0109 0.0109
Brugia malayi hypothetical protein 0.0056 0.0109 0.0238
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0165 0.0464 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0004 0.0031
Schistosoma mansoni neuropeptide receptor 0.0056 0.0109 0.0109
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0088 0.0894
Schistosoma mansoni ap endonuclease 0.0022 0.0001 0.0001
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0165 0.0464 0.0464
Onchocerca volvulus 0.0056 0.0109 0.1265
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0056 0.0109 0.0108
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0165 0.0464 1
Echinococcus granulosus metabotropic glutamate receptor 5 0.0141 0.0384 0.0384
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0004 0.0065
Schistosoma mansoni biogenic amine receptor 0.0056 0.0109 0.0109
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0108
Trichomonas vaginalis esterase, putative 0.0036 0.0046 0.0464

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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