Detailed information for compound 1246483

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.485 | Formula: C22H31NO5
  • H donors: 1 H acceptors: 1 LogP: 3.39 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](CO/N=C\[C@H]([C@@H](C(C)C)OCc1ccccc1)C)COCc1ccco1
  • InChi: 1S/C22H31NO5/c1-17(2)22(27-13-19-8-5-4-6-9-19)18(3)12-23-28-15-20(24)14-25-16-21-10-7-11-26-21/h4-12,17-18,20,22,24H,13-16H2,1-3H3/b23-12-/t18-,20+,22-/m1/s1
  • InChiKey: BGSGDWJKMVQQEV-QBRFEOMBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0236 0.1379 0.5011
Echinococcus granulosus dnaJ subfamily B 0.0395 0.2408 0.602
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0023
Plasmodium vivax 26S protease regulatory subunit 10B, putative 0.0035 0.0075 0.0274
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0059 0.0232 0.0824
Leishmania major hypothetical protein, conserved 0.0079 0.0362 0.1298
Echinococcus multilocularis peregrin 0.0148 0.0806 0.0806
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0227 0.1317 0.4777
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.031
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0085 0.0104
Brugia malayi Cytochrome P450 family protein 0.0031 0.005 0.006
Brugia malayi proteasome subunit alpha type 4 0.0208 0.1195 0.1456
Brugia malayi Carboxylesterase family protein 0.0141 0.0763 0.093
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0025 0.001 0.0015
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.007 0.0303 0.1101
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0237 0.1385 0.5032
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Loa Loa (eye worm) hypothetical protein 0.0047 0.0153 0.0186
Leishmania major proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Loa Loa (eye worm) hypothetical protein 0.0063 0.0256 0.0312
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0041 0.0043
Onchocerca volvulus 0.0024 0.0003 0.0003
Onchocerca volvulus 26S protease regulatory subunit 8 homolog 0.0035 0.0075 0.0081
Onchocerca volvulus 0.0023 0.000000050219 0.000000053622
Leishmania major hypothetical protein, conserved 0.0179 0.1006 0.3642
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0227 0.1317 0.3293
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.1464 0.1784
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0224 0.1298 0.1701
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0036 0.0082 0.0088
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0034 0.0067 0.0067
Echinococcus granulosus peregrin 0.0148 0.0806 0.2016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0174 0.0975 0.2698
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0228 0.1328 0.332
Loa Loa (eye worm) RPN-3 protein 0.007 0.0303 0.0369
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.058 0.3605 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0448 0.2752 1
Brugia malayi AF-10 protein 0.0048 0.0161 0.0196
Schistosoma mansoni protein phosphatase 2C 0.0079 0.0362 0.0905
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0179 0.1008 0.3652
Entamoeba histolytica proteasome regulatory subunit, putative 0.0052 0.0183 0.0242
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Onchocerca volvulus 0.0209 0.1203 0.1284
Schistosoma mansoni lipoxygenase 0.0058 0.0224 0.0561
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Plasmodium vivax proteasome subunit beta type-7, putative 0.0217 0.1253 0.4555
Schistosoma mansoni proteasome regulatory subunit-related 0.0059 0.0232 0.058
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0054 0.0201 0.0214
Leishmania major trypanothione reductase 0.0076 0.0342 0.1224
Echinococcus multilocularis lysine specific demethylase 6a 0.0079 0.0362 0.0362
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0258 0.1517 0.3793
Loa Loa (eye worm) hypothetical protein 0.0102 0.0507 0.0617
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0052 0.0183 0.0223
Brugia malayi Proteasome A-type and B-type family protein 0.0224 0.1298 0.1581
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0224 0.1298 0.1722
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0448 0.2752 0.6879
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0052 0.0183 0.0664
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Brugia malayi 26S protease regulatory subunit 8 0.0035 0.0075 0.0092
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0326 0.1958 0.7117
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0157 0.0866 0.2164
Echinococcus multilocularis proteasome (prosome, macropain) 0.0448 0.2752 0.2752
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0236 0.1379 0.1472
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0019 0.002
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0227 0.1317 0.3293
Brugia malayi CXXC zinc finger family protein 0.0028 0.0028 0.0034
Schistosoma mansoni ets-related 0.0229 0.1329 0.3321
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0507 0.0617
Mycobacterium tuberculosis Probable oxidoreductase 0.0193 0.11 0.3048
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0091
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0036 0.0082 0.0205
Brugia malayi 20S proteasome alpha5 subunit 0.0258 0.1517 0.1848
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0966 0.1031
Loa Loa (eye worm) proteasome regulatory particle 0.0065 0.0271 0.033
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Loa Loa (eye worm) hypothetical protein 0.0285 0.1696 0.2065
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0179 0.1008 1
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.1464 0.1784
Brugia malayi 26S proteasome regulatory complex subunit p97 0.007 0.0299 0.0365
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0348 0.0871
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0036 0.0082 0.0278
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0408 0.0436
Plasmodium vivax proteasome subunit beta type-2, putative 0.0227 0.1317 0.4788
Echinococcus granulosus intermediate filament protein 0.0028 0.0029 0.0074
Echinococcus multilocularis musashi 0.0028 0.0029 0.0029
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.022 0.055
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0909 0.097
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.001 0.0012
Echinococcus multilocularis PHD finger protein rhinoceros 0.0148 0.0806 0.0806
Onchocerca volvulus 0.0036 0.0082 0.0088
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0059 0.0231 0.0838
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0054 0.0201 0.0244
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5514
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0276 0.1638 0.4095
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0179 0.1008 0.3652
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0065 0.0271 0.0271
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Loa Loa (eye worm) glutathione reductase 0.0076 0.0342 0.0416
Schistosoma mansoni 26S protease regulatory subunit 0.0035 0.0075 0.0189
Brugia malayi hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0046
Onchocerca volvulus 0.0096 0.0467 0.0498
Onchocerca volvulus 0.0024 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0395 0.2408 0.602
Schistosoma mansoni hypothetical protein 0.0097 0.0478 0.1194
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0019 0.0069
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0047 0.0152 0.0553
Schistosoma mansoni lamin 0.0028 0.0029 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0052 0.0183 0.0664
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0408 0.2494 0.2494
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0153 0.0186
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0065 0.0271 0.0966
Leishmania major proteasome alpha 1 subunit, putative 0.0236 0.1379 0.5001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0048
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0059 0.0232 0.0824
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Brugia malayi chromobox protein homolog 3 0.008 0.0369 0.0449
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.058 0.3605 1
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0238 0.139 0.5051
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Plasmodium vivax proteasome subunit beta type-6, putative 0.0238 0.139 0.5051
Entamoeba histolytica proteasome regulatory subunit, putative 0.0054 0.0199 0.0264
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0019 0.0069
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0035 0.0075 0.0189
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0036 0.0082 0.0082
Loa Loa (eye worm) proteasome 26S subunit 0.0035 0.0075 0.0092
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0054 0.0201 0.0729
Brugia malayi hypothetical protein 0.0477 0.2936 0.3576
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Mycobacterium tuberculosis Probable reductase 0.0174 0.0975 0.2698
Echinococcus multilocularis JmjC domain containing protein 4 0.0079 0.0362 0.0362
Brugia malayi proteasome subunit alpha type 2 0.0246 0.1443 0.1757
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0224 0.1298 0.3245
Trypanosoma cruzi 20S proteasome subunit 0.0227 0.1317 0.4777
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.2408 0.2408
Loa Loa (eye worm) carboxylesterase 0.0024 0.0003 0.0003
Onchocerca volvulus 0.0039 0.0098 0.0105
Schistosoma mansoni intermediate filament proteins 0.0028 0.0029 0.0074
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.007 0.0299 0.1088
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0224 0.0561
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Echinococcus granulosus proteasome subunit alpha type 6 0.0259 0.1528 0.3821
Brugia malayi intermediate filament protein 0.0028 0.0029 0.0036
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0448 0.2752 0.3634
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0054 0.0199 0.0497
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.139 0.1693
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.007 0.0299 0.0299
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0257 0.0706
Loa Loa (eye worm) PAS-3 protein 0.0208 0.1195 0.1456
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5011
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0144 0.0778 0.1944
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0034 0.0067 0.0224
Schistosoma mansoni NADH dehydrogenase subunit 1 0.0039 0.0098 0.0245
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0047 0.0152 0.038
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0157 0.0866 0.0866
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0408 0.2494 0.6235
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0038 0.0095 0.0327
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0059 0.0231 0.0281
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0153 0.0153
Trypanosoma brucei proteasome beta 7 subunit 0.0224 0.1298 0.4706
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0065 0.0271 0.033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0233 0.0845
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0054 0.0201 0.0266
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0257 0.0642
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0179 0.1008 0.2521
Schistosoma mansoni cpg binding protein 0.0029 0.0038 0.0095
Brugia malayi SET domain containing protein 0.0031 0.0048 0.0059
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0193 0.11 0.3048
Echinococcus granulosus proteasome subunit beta t family 0.0227 0.1317 0.3293
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0276 0.1638 0.1749
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0195 0.0238
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0217 0.1253 0.1527
Mycobacterium tuberculosis Possible formate hydrogenlyase HycD (FHL) 0.0039 0.0098 0.0265
Plasmodium vivax JmjC domain containing protein 0.0079 0.0362 0.1316
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0258 0.1517 0.2013
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0258 0.1517 0.162
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0054 0.0201 0.0244
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0019 0.0069
Loa Loa (eye worm) proteasome Regulatory Particle 0.0059 0.0231 0.0281
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0034 0.0067 0.0224
Loa Loa (eye worm) PHD-finger family protein 0.0148 0.0806 0.0982
Plasmodium vivax proteasome subunit beta type-3, putative 0.0227 0.1317 0.4788
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Echinococcus multilocularis lamin 0.0028 0.0029 0.0029
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0052 0.0183 0.0645
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0006 0.0021
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0065 0.0271 0.0966
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0035 0.0075 0.0081
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0224 0.1298 0.3245
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0186 0.1051 0.1051
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0047 0.0152 0.0533
Mycobacterium ulcerans formate hydrogenlyase HycD 0.0039 0.0098 0.0265
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Giardia lamblia 20S proteasome alpha subunit 2 0.0246 0.1443 0.1893
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0059 0.0232 0.0843
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0038 0.0095 0.0102
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0059 0.0231 0.0819
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0035 0.0075 0.0254
Leishmania major proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Toxoplasma gondii tat-binding family protein, putative 0.0035 0.0075 0.0274
Loa Loa (eye worm) fli-1 protein 0.0229 0.1329 0.1618
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0085 0.0213
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0036 0.0082 0.0109
Brugia malayi Fli-1 protein 0.0229 0.1329 0.1618
Plasmodium vivax proteasome subunit beta type-5, putative 0.0448 0.2752 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0054 0.0199 0.0703
Loa Loa (eye worm) carboxylesterase 0.0141 0.0763 0.093
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0019 0.0069
Brugia malayi glutaminase DH11.1 0.0274 0.1622 0.1975
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0179 0.1008 0.3665
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Toxoplasma gondii thioredoxin reductase 0.0076 0.0342 0.1242
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0059 0.0232 0.0248
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0336 0.0839
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0408 0.2494 0.6235
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0342 0.0942
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0603 0.3755 0.3755
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0271 0.036
Schistosoma mansoni hypothetical protein 0.0144 0.0778 0.1944
Onchocerca volvulus 0.0024 0.0003 0.0003
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.001 0.0026
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0059 0.0232 0.058
Echinococcus granulosus proteasome subunit alpha type 2 0.0246 0.1443 0.3607
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0049
Echinococcus multilocularis chromobox protein 1 0.0143 0.0777 0.0777
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.007 0.0303 0.0303
Giardia lamblia Hypothetical protein 0.0065 0.0271 0.0335
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0029 0.0036
Onchocerca volvulus 0.0028 0.0029 0.0031
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0227 0.1317 0.4777
Plasmodium falciparum 26S protease regulatory subunit 10B, putative 0.0035 0.0075 0.0274
Loa Loa (eye worm) hypothetical protein 0.0148 0.0806 0.0982
Schistosoma mansoni alpha glucosidase 0.0037 0.0085 0.0213
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.024 0.1404 0.1499
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0054 0.0201 0.0214
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0054 0.0201 0.0244
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.0161 0.0586
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0036 0.0082 0.0084
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Brugia malayi Proteasome A-type and B-type family protein 0.0448 0.2752 0.3351
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Schistosoma mansoni multiubiquitin binding protein S5a 0.0038 0.0095 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Schistosoma mansoni lamin 0.0028 0.0029 0.0074
Echinococcus granulosus cpg binding protein 0.0029 0.0038 0.0095
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0059 0.0232 0.0232
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0174 0.0975 0.2698
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0041 0.0114 0.0122
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0246 0.1443 0.5243
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0298 0.0298
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0224 0.1298 0.1386
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0003 0.0006
Toxoplasma gondii hypothetical protein 0.0048 0.0157 0.057
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0386 0.2346 0.2857
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0718 0.0875
Echinococcus granulosus lamin 0.0028 0.0029 0.0074
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0047 0.0152 0.0152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Echinococcus granulosus GPCR family 2 0.0047 0.0153 0.0382
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0227 0.1317 0.1748
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0038 0.0096 0.0103
Schistosoma mansoni alpha-glucosidase 0.0142 0.0769 0.1923
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.007 0.0303 0.0369
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0109 0.0109
Trichomonas vaginalis 26S proteasome subunit, putative 0.0054 0.0199 0.0212
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1291 0.8211 1
Plasmodium falciparum phd finger protein, putative 0.0148 0.0806 0.293
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0065 0.0271 0.0985
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.022 0.0268
Echinococcus granulosus neuroligin 0.0024 0.0003 0.0006
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.005 0.0172 0.0625
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0054 0.0201 0.0729
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0298 0.0745
Echinococcus granulosus cyclin 0.0028 0.0029 0.0073
Schistosoma mansoni hypothetical protein 0.0493 0.3041 0.7602
Schistosoma mansoni chromobox protein 0.0143 0.0777 0.1943
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0038 0.0096 0.0349
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0224 0.1298 0.4706
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.0039 0.0098 0.012
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 10 0.0025 0.001 0.0015
Plasmodium falciparum proteasome subunit beta type-5 0.0448 0.2752 1
Echinococcus multilocularis GPCR, family 2 0.0047 0.0153 0.0153
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0342 0.0416
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0246 0.1443 0.1757
Brugia malayi PHD-finger family protein 0.0148 0.0806 0.0982
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0052 0.0183 0.0223
Brugia malayi PHD-finger family protein 0.005 0.0171 0.0209
Schistosoma mansoni 26S protease regulatory subunit S10b 0.0035 0.0075 0.0189
Giardia lamblia Proteasome subunit beta type 3 0.0227 0.1317 0.1727
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.024 0.1404 0.1862
Brugia malayi hypothetical protein 0.0039 0.0098 0.012
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0342 0.1242
Plasmodium vivax proteasome subunit alpha type-3, putative 0.024 0.1404 0.5101
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5514
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0019 0.0046
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.007 0.0299 0.107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Brugia malayi MH2 domain containing protein 0.0134 0.0718 0.0875
Loa Loa (eye worm) hypothetical protein 0.0052 0.0183 0.0223
Plasmodium vivax proteasome subunit beta type-1, putative 0.0276 0.1638 0.5953
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0179 0.1008 0.0128
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0113
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0081 0.0372 0.0372
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0034 0.0067 0.0224
Brugia malayi Ets-domain containing protein 0.0075 0.0336 0.0409
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0448 0.2752 0.3351
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0258 0.1517 0.5514
Schistosoma mansoni hypothetical protein 0.0148 0.0806 0.2016
Loa Loa (eye worm) hypothetical protein 0.0477 0.2936 0.3576
Plasmodium vivax SET domain protein, putative 0.0186 0.1051 0.3819
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0217 0.0231
Schistosoma mansoni cpg binding protein 0.0029 0.0038 0.0095
Echinococcus granulosus histone lysine methyltransferase setb 0.0186 0.1051 0.2627
Echinococcus granulosus chromobox protein 1 0.0143 0.0777 0.1943
Giardia lamblia 20S proteasome alpha subunit 5 0.0258 0.1517 0.1992
Giardia lamblia 26S protease regulatory subunit 7 0.0035 0.0075 0.0075
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0236 0.1379 0.3447
Toxoplasma gondii proteasome subunit alpha type, putative 0.0237 0.1385 0.5032
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.029
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0478 0.0582
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0085 0.0104
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0049
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0049
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5011
Echinococcus multilocularis chromobox protein 1 0.0143 0.0777 0.0777
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0038 0.0096 0.033
Echinococcus multilocularis proteasome subunit beta type 6 0.0238 0.139 0.139
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0054 0.0201 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0217 0.0231
Schistosoma mansoni hypothetical protein 0.0493 0.3041 0.7602
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0227 0.1317 0.4788
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0019 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0049
Loa Loa (eye worm) glutaminase 2 0.0274 0.1622 0.1975
Echinococcus multilocularis lysine specific demethylase 5A 0.0298 0.1776 0.1776
Brugia malayi Pre-SET motif family protein 0.0186 0.1051 0.128
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.029
Plasmodium vivax 26S proteasome regulatory subunit RPN10, putative 0.0025 0.001 0.0036
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0054 0.0199 0.0703
Echinococcus granulosus lysine specific demethylase 6a 0.0079 0.0362 0.0905
Onchocerca volvulus Heterochromatin protein 1 homolog 0.008 0.0369 0.0394
Plasmodium falciparum proteasome subunit beta type-4 0.0224 0.1298 0.4717
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0209 0.1203 0.3007
Echinococcus granulosus geminin 0.0493 0.3041 0.7602
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0037 0.0089 0.0118
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0019 0.0046
Mycobacterium tuberculosis Probable dehydrogenase 0.0174 0.0975 0.2698
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0259 0.1528 0.1861
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0059 0.0231 0.0231
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0259 0.1528 0.5554
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Echinococcus granulosus survival motor neuron protein 1 0.0477 0.2936 0.734
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0448 0.2752 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Schistosoma mansoni glutaminase 0.0274 0.1622 0.4054
Brugia malayi Proteasome subunit alpha type 7-1 0.0326 0.1958 0.2385
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0179 0.1008 0.1338
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0966 0.1031
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0003 0.0006
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0047 0.0152 0.038
Brugia malayi CHD4 protein 0.0025 0.001 0.0012
Echinococcus granulosus JmjC domain containing protein 4 0.0079 0.0362 0.0905
Echinococcus granulosus jumonji domain containing 1A 0.0079 0.0362 0.0905
Onchocerca volvulus Alhambra homolog 0.0148 0.0806 0.0861
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.024 0.1404 0.3509
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0038 0.0095 0.0327
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0343 0.2071 0.7525
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0258 0.1517 0.2013
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0238 0.139 0.3474
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0246 0.1443 0.5243
Echinococcus granulosus Proteasome subunit alpha beta 0.024 0.1404 0.3509
Trypanosoma brucei glucosidase, putative 0.0037 0.0085 0.029
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.001 0.001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0193 0.11 0.3048
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.007 0.0299 0.032
Echinococcus multilocularis jumonji domain containing 1A 0.0079 0.0362 0.0362
Leishmania major proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0065 0.0271 0.0985
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.007 0.0299 0.1088
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.005 0.006
Loa Loa (eye worm) hypothetical protein 0.0343 0.2071 0.2522
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0161 0.0566
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Echinococcus multilocularis Chromobox protein 3 0.0023 0.000000050219 0.000000050219
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0038 0.0096 0.0349
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0003 0.0003
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0035 0.0075 0.0254
Echinococcus granulosus phd:f box containing protein 0.0079 0.0362 0.0905
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0227 0.1317 0.4788
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0036 0.0082 0.0082
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0208 0.1198 0.1279
Onchocerca volvulus Notchless protein homolog 0.024 0.1404 0.1499
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0298 0.0363
Onchocerca volvulus 0.0028 0.0028 0.003
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0038 0.0096 0.0096
Leishmania major proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0036 0.0082 0.0278
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Brugia malayi Proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.007 0.0299 0.107
Brugia malayi 26S protease regulatory subunit 6A 0.0038 0.0096 0.0117
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.026 0.0317
Entamoeba histolytica proteasome regulatory subunit, putative 0.0059 0.0232 0.0308
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0258 0.1517 0.1848
Brugia malayi glutathione reductase 0.0076 0.0342 0.0416
Echinococcus granulosus acetylcholinesterase 0.0141 0.0763 0.1908
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Echinococcus granulosus chromobox protein 1 0.0143 0.0777 0.1943
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.139 0.1484
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0641 0.4 1
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0054 0.0201 0.0201
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.005 0.0171 0.0209
Brugia malayi Probable 26S protease regulatory subunit 4 0.0036 0.0082 0.01
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0091
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0059 0.0232 0.0843
Brugia malayi Bromodomain containing protein 0.0148 0.0806 0.0982
Echinococcus multilocularis proteasome subunit beta type 7 0.0641 0.4 0.4
Schistosoma mansoni gliotactin 0.0024 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0054 0.0201 0.0729
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0276 0.1638 0.2173
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0258 0.1517 0.5505
Schistosoma mansoni phosphatidylserine receptor 0.0079 0.0362 0.0905
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0034 0.0067 0.0168
Schistosoma mansoni gabp alpha 0.0075 0.0336 0.0839
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0079 0.0362 0.0905
Toxoplasma gondii 26S proteasome regulatory subunit 0.0035 0.0075 0.0274
Trichomonas vaginalis set domain proteins, putative 0.1469 0.9365 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0342 0.1224
Schistosoma mansoni jumonji/arid domain-containing protein 0.0299 0.1786 0.4465
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0237 0.1385 0.3462
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0273 0.0683
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Loa Loa (eye worm) hypothetical protein 0.0149 0.0812 0.0989
Trichomonas vaginalis chromobox protein, putative 0.0143 0.0777 0.083
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0065 0.0271 0.0289
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0038 0.0096 0.0117
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0087 0.0408 0.0436
Onchocerca volvulus 0.0097 0.0478 0.051
Plasmodium vivax 26S protease regulatory subunit 8, putative 0.0035 0.0075 0.0274
Brugia malayi 26S proteasome subunit-like protein 0.0025 0.001 0.0012
Brugia malayi Proteasome A-type and B-type family protein 0.0641 0.4 0.4872
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0812 0.0989
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0326 0.1958 0.4895
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0052 0.0183 0.0457
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0918 0.1118
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0343 0.2071 0.5177
Giardia lamblia PHD finger protein 15 0.0148 0.0806 0.1047
Toxoplasma gondii proteasome subunit beta type, putative 0.0448 0.2752 1
Giardia lamblia 26S protease regulatory subunit 8 0.0035 0.0075 0.0075
Leishmania major proteasome regulatory ATPase subunit 0.0035 0.0075 0.0254
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0059 0.0231 0.0246
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0035 0.0075 0.0254
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0236 0.1379 0.5001
Giardia lamblia 26S protease regulatory subunit 6B 0.0036 0.0082 0.0084
Loa Loa (eye worm) hypothetical protein 0.0141 0.0763 0.093
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0161 0.0566
Echinococcus granulosus carboxylesterase 5A 0.0141 0.0763 0.1908
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Schistosoma mansoni 26S proteasome subunit S9 0.0065 0.0271 0.0678
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.022 0.022
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0035 0.0075 0.0075
Echinococcus multilocularis jumonji domain containing protein 0.0206 0.1182 0.1182
Onchocerca volvulus 0.0063 0.0256 0.0274
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0113
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0038 0.0096 0.0128
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0034 0.0067 0.0064
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0918 0.2295
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0298 0.1065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Echinococcus granulosus Chromobox protein 3 0.0023 0.000000050219 0.00000012554
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0059 0.0231 0.0838
Schistosoma mansoni chromobox protein 0.0143 0.0777 0.1943
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0003 0.0006
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0326 0.1958 0.2598
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0217 0.1253 0.1663
Brugia malayi Carboxylesterase family protein 0.0141 0.0763 0.093
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0259 0.1528 0.3821
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0153 0.0186
Schistosoma mansoni hypothetical protein 0.0048 0.0161 0.0403
Brugia malayi jmjC domain containing protein 0.0603 0.3755 0.4573
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0003 0.0003
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0036 0.0082 0.0298
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0238 0.139 0.1843
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0036 0.0082 0.0298
Echinococcus multilocularis carboxylesterase 5A 0.0141 0.0763 0.0763
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0257 0.0915
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0059 0.0231 0.0576
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0035 0.0075 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0812 0.0989
Echinococcus granulosus adhesion regulating molecule 1 0.0343 0.2071 0.5177
Toxoplasma gondii proteasome subunit alpha type, putative 0.0147 0.0798 0.2899
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0085 0.0091
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0036 0.0082 0.0278
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0019 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0052 0.0183 0.0645
Brugia malayi NADH dehydrogenase subunit 1, identical 0.0039 0.0098 0.012
Plasmodium falciparum thioredoxin reductase 0.0026 0.0019 0.0069
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0217 0.1253 0.1338
Loa Loa (eye worm) proteasome 26S subunit 0.0034 0.0067 0.0082
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0038 0.0095 0.0238
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0237 0.1385 0.3462
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0079 0.0362 0.1316
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0019 0.0049
Trichomonas vaginalis glutaminase, putative 0.0274 0.1622 0.1732
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0408 0.0436
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0048 0.0161 0.0586
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Entamoeba histolytica proteasome regulatory subunit, putative 0.0038 0.0095 0.0126
Echinococcus granulosus lysine specific demethylase 5A 0.0299 0.1786 0.4465
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0054 0.0199 0.0212
Toxoplasma gondii proteasome subunit alpha1, putative 0.0259 0.1528 0.5554
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0276 0.1638 0.5953
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0059 0.0231 0.0819
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0237 0.1385 0.1385
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0059 0.0231 0.0281
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0036
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0236 0.1379 0.3447
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0019 0.0069
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0448 0.2752 0.7632
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Toxoplasma gondii peptidase, T1 family protein 0.024 0.1404 0.5101
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0298 0.0363
Echinococcus multilocularis proteasome subunit alpha type 6 0.0259 0.1528 0.1528
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0326 0.1958 0.2385
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.007 0.0303 0.1083
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0218 0.1259 0.1344
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.01
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0038 0.0096 0.0102
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0918 0.0918
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0047 0.0152 0.0553
Brugia malayi Ubiquitin interaction motif family protein 0.0038 0.0095 0.0116
Brugia malayi Proteasome subunit alpha type 1 0.0207 0.119 0.1449
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0054 0.0201 0.0501
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0053 0.0189 0.0667
Loa Loa (eye worm) jmjC domain-containing protein 0.0305 0.1827 0.2225
Loa Loa (eye worm) acetylcholinesterase 1 0.0141 0.0763 0.093
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0227 0.1317 0.3293
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0179 0.1008 0.3665
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0191
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0035 0.0075 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0059 0.0232 0.0843
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Loa Loa (eye worm) proteasome subunit beta type 3 0.0227 0.1317 0.1605
Entamoeba histolytica hypothetical protein 0.0047 0.0152 0.0202
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0257 0.0642
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0227 0.1317 0.4788
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0019 0.0046
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0038 0.0096 0.024
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0019 0.0049
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.0362 0.0441
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0258 0.1517 0.1517
Toxoplasma gondii proteasome regulatory subunit 0.0054 0.0201 0.0729
Treponema pallidum fructose-bisphosphate aldolase 0.1187 0.7539 1
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0065 0.0271 0.0678
Echinococcus granulosus proteasome subunit beta type 7 0.0641 0.4 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0237 0.1385 0.1478
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0918 0.1118
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0369 0.0394
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0041 0.0043
Toxoplasma gondii SAC3/GANP family protein 0.0052 0.0183 0.0664
Plasmodium falciparum 26S protease regulatory subunit 8, putative 0.0035 0.0075 0.0274
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.007 0.0299 0.107
Schistosoma mansoni survival motor neuron protein 0.0097 0.0478 0.1194
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0054 0.0199 0.0722
Brugia malayi proteasome subunit beta type 1 0.0276 0.1638 0.1995
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0022 0.0023
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0054 0.0201 0.0244
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0019 0.002
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0227 0.1317 0.1317
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Leishmania major proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0059 0.0231 0.0576
Schistosoma mansoni alpha-glucosidase 0.0142 0.0769 0.1923
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0019 0.0049
Mycobacterium ulcerans proteasome PrcB 0.0448 0.2752 0.7632
Toxoplasma gondii ubiquitin interaction motif family protein 0.0025 0.001 0.0036
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0054 0.0201 0.0501
Loa Loa (eye worm) proteasome subunit alpha type 3 0.024 0.1404 0.171
Giardia lamblia 26S protease regulatory subunit 6A 0.0038 0.0096 0.0103
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1187 0.7539 1
Loa Loa (eye worm) carboxylesterase 0.0024 0.0003 0.0003
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0217 0.1253 0.4555
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0153 0.0382
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.001 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0178 0.1003 0.2507
Loa Loa (eye worm) jmjC domain-containing protein 0.0299 0.1786 0.2175
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0298 0.0396
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.007 0.0303 0.1083
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0806 0.293
Leishmania major proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Brugia malayi Probable 26S protease regulatory subunit S10B 0.0035 0.0075 0.0092
Loa Loa (eye worm) hypothetical protein 0.0052 0.0183 0.0223
Loa Loa (eye worm) PCI domain-containing protein 0.0059 0.0232 0.0283
Giardia lamblia 20S proteasome alpha subunit 3 0.0237 0.1385 0.1816
Plasmodium falciparum glutathione reductase 0.0026 0.0019 0.0069
Brugia malayi hypothetical protein 0.0024 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0386 0.2346 0.2857
Loa Loa (eye worm) hypothetical protein 0.0064 0.0265 0.0323
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0238 0.139 0.1823
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0038 0.0096 0.0349
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0259 0.1528 0.1632
Loa Loa (eye worm) RPT-2 protein 0.0036 0.0082 0.01
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0186 0.1051 0.3819
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0036 0.0082 0.0278
Brugia malayi Thioredoxin reductase 0.0076 0.0342 0.0416
Loa Loa (eye worm) PCI domain-containing protein 0.0054 0.0199 0.0242
Toxoplasma gondii PCI domain-containing protein 0.007 0.0303 0.1101
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0059 0.0231 0.0838
Giardia lamblia 20S proteasome alpha subunit 6 0.0236 0.1379 0.1808
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0029 0.0036
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0448 0.2752 0.2938
Giardia lamblia 20S proteasome alpha subunit 7 0.024 0.1404 0.1841
Onchocerca volvulus 0.0028 0.0029 0.0031
Echinococcus granulosus jumonji domain containing protein 0.0206 0.1182 0.2954
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0918 0.0918
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.007 0.0303 0.1083
Schistosoma mansoni hypothetical protein 0.0157 0.0866 0.2164
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0448 0.2752 1
Brugia malayi Proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.025 0.0625
Echinococcus multilocularis cpg binding protein 0.0029 0.0038 0.0038
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0179 0.1006 0.3655
Echinococcus multilocularis neuroligin 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0144 0.0778 0.2152
Toxoplasma gondii proteasome 26S regulatory subunit 0.0037 0.0089 0.0323
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0237 0.1385 0.1837
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0448 0.2752 0.365
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0224 0.1298 0.1581
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Plasmodium vivax proteasome subunit beta type-4, putative 0.0224 0.1298 0.4717
Brugia malayi PCI domain containing protein 0.0054 0.0199 0.0242
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0036 0.0082 0.0278
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0054 0.0199 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0369 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0035 0.0075 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0237 0.1385 0.5032
Leishmania major proteasome beta 7 subunit, putative 0.0224 0.1298 0.4706
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0362 0.0905
Schistosoma mansoni jumonji/arid domain-containing protein 0.0299 0.1786 0.4465
Echinococcus multilocularis acetylcholinesterase 0.0141 0.0763 0.0763
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0148 0.0806 0.293
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0336 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Loa Loa (eye worm) proteasome subunit beta type 1 0.0276 0.1638 0.1995
Loa Loa (eye worm) hypothetical protein 0.0079 0.0362 0.0441
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0054 0.0201 0.071
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0054 0.0201 0.0729
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0236 0.1379 0.1829
Brugia malayi PCI domain containing protein 0.0059 0.0232 0.0283
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0019 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Leishmania major proteasome beta 5 subunit, putative 0.0448 0.2752 1
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0259 0.1528 0.5554
Schistosoma mansoni 26S protease regulatory subunit 0.0036 0.0082 0.0205
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.001 0.0026
Loa Loa (eye worm) proteasome subunit beta type 2 0.0227 0.1317 0.1605
Plasmodium falciparum JmjC domain-containing protein, putative 0.0079 0.0362 0.1316
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0174 0.0975 0.2698
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0047 0.0152 0.0553
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.058 0.3605 1
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0052 0.0183 0.0457
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0153 0.0186
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0048
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0036 0.0082 0.0109
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0035 0.0075 0.0254
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.022 0.0781
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0144 0.0778 0.2152
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Echinococcus multilocularis Proteasome, subunit alpha beta 0.024 0.1404 0.1404
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0257 0.0933
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0326 0.1958 0.2598
Toxoplasma gondii PCI domain-containing protein 0.0065 0.0271 0.0985
Toxoplasma gondii PCI domain-containing protein 0.0054 0.0199 0.0722
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 7 0.0034 0.0067 0.0064
Mycobacterium ulcerans proteasome PrcA 0.0179 0.1008 0.2792
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0246 0.1443 0.1914
Schistosoma mansoni cpg binding protein 0.0028 0.0028 0.0069
Entamoeba histolytica proteasome regulatory subunit, putative 0.0059 0.0231 0.0306
Schistosoma mansoni hypothetical protein 0.0102 0.0507 0.1267
Echinococcus multilocularis acetylcholinesterase 0.0141 0.0763 0.0763
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0236 0.1379 0.1679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0193 0.11 0.0478
Brugia malayi jmjC domain containing protein 0.0299 0.1786 0.2175
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0054 0.0201 0.0729
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0227 0.1317 0.1748
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0326 0.1958 0.7117
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0085 0.029
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0034 0.0067 0.0224
Toxoplasma gondii proteasome beta subunit 0.0227 0.1317 0.4788
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0019 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0153 0.0153
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Echinococcus multilocularis cyclin 0.0028 0.0029 0.0029
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0276 0.1638 0.1638
Echinococcus multilocularis adhesion regulating molecule 1 0.0343 0.2071 0.2071
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0036 0.0082 0.0205
Echinococcus granulosus PHD finger protein rhinoceros 0.0148 0.0806 0.2016
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0448 0.2752 0.6756
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0298 0.0745
Giardia lamblia Proteasome subunit beta type 2 0.0227 0.1317 0.1727
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0059 0.0232 0.0824
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0079 0.0362 0.1316
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0036 0.0082 0.0088
Toxoplasma gondii heat shock protein hslv, putative 0.0179 0.1008 0.3665
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0812 0.0989
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0054 0.0201 0.0266
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Giardia lamblia 20S proteasome alpha subunit 1 0.0259 0.1528 0.2007
Echinococcus granulosus acetylcholinesterase 0.0141 0.0763 0.1908
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0003 0.0003
Plasmodium falciparum 26S proteasome regulatory subunit RPN10, putative 0.0025 0.001 0.0036
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0224 0.1298 0.1298
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0343 0.2071 0.2522
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0179 0.1008 0.2792
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0028 0.0034
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Plasmodium vivax hypothetical protein, conserved 0.005 0.0172 0.0625
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0806 0.293
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0029 0.0036
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.139 0.1693
Schistosoma mansoni acetylcholinesterase 0.0024 0.0003 0.0006
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0054 0.0201 0.0201
Echinococcus multilocularis lamin dm0 0.0028 0.0029 0.0029
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0217 0.1253 0.4555
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0276 0.1638 0.5953
Loa Loa (eye worm) hypothetical protein 0.0141 0.0763 0.093
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5001
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0085 0.0085
Entamoeba histolytica proteasome regulatory subunit, putative 0.007 0.0303 0.0402
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1187 0.7539 1
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Echinococcus granulosus proteasome subunit beta type 6 0.0238 0.139 0.3474
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0037 0.0089 0.0303
Toxoplasma gondii proteasome subunit 0.0238 0.139 0.5051
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0036 0.0082 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Giardia lamblia 20S proteasome alpha subunit 4 0.0326 0.1958 0.2579
Echinococcus granulosus proteasome prosome macropain 0.0448 0.2752 0.6879
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.007 0.0299 0.0365
Echinococcus multilocularis proteasome subunit alpha type 2 0.0246 0.1443 0.1443
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0603 0.3755 0.9387
Plasmodium falciparum thioredoxin reductase 0.0076 0.0342 0.1242
Leishmania major proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0038 0.0095 0.0095
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0246 0.1443 0.3607
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0036 0.0082 0.0205
Giardia lamblia Fructose-bisphosphate aldolase 0.1187 0.7539 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.002
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Echinococcus multilocularis phd:f box containing protein 0.0079 0.0362 0.0362
Echinococcus granulosus 26S protease regulatory subunit 8 0.0035 0.0075 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0246 0.1443 0.5243
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0053 0.0194 0.0705
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Giardia lamblia Proteasome subunit beta type 1 0.0276 0.1638 0.2153
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0019
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0054 0.0201 0.0501
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.01
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0081 0.0372 0.0931
Echinococcus granulosus transcription factor Dp 1 0.004 0.0109 0.0271
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0153 0.0382
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0259 0.1528 0.2027
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0032 0.0058 0.0052
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.001 0.0011
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Schistosoma mansoni hypothetical protein 0.0386 0.2346 0.5865
Echinococcus granulosus Proteasome subunit alpha type 7 0.0326 0.1958 0.4895
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0224 0.1298 0.4717
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0035 0.0075 0.0075
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0032 0.0058 0.0062
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0257 0.0257
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0718 0.0875
Brugia malayi proteasome subunit alpha type 1 0.0236 0.1379 0.1679
Echinococcus granulosus lamin dm0 0.0028 0.0029 0.0074
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.022 0.055
Trichomonas vaginalis chromobox protein, putative 0.0143 0.0777 0.083
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0054 0.0199 0.0199
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0276 0.1638 0.4095
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.024 0.1404 0.1862
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Brugia malayi Ets-domain containing protein 0.0075 0.0336 0.0409
Onchocerca volvulus 0.0036 0.0082 0.0088
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0336 0.0336
Brugia malayi Pre-SET motif family protein 0.1291 0.8211 1
Brugia malayi proteasome subunit alpha type 3 0.024 0.1404 0.171
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0179 0.1008 0.3652
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.007 0.0299 0.0373
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0007
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0065 0.0271 0.0966
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.024 0.1404 0.5101
Leishmania major proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Brugia malayi Heterochromatin protein 1 0.0143 0.0777 0.0947
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0003 0.0006
Loa Loa (eye worm) glutaminase 0.0274 0.1622 0.1975
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0052 0.0183 0.0183
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Trypanosoma brucei proteasome alpha 7 subunit 0.024 0.1404 0.5091
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0348 0.0348
Echinococcus multilocularis survival motor neuron protein 1 0.0477 0.2936 0.2936
Brugia malayi proteasome subunit beta type 2 0.0227 0.1317 0.1605
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0236 0.1379 0.1379
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0019 0.0069
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0227 0.1317 0.1317
Schistosoma mansoni jumonji domain containing protein 0.0503 0.311 0.7774
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0144 0.0778 0.7669
Plasmodium falciparum glutathione reductase 0.0076 0.0342 0.1242
Plasmodium vivax glutathione reductase, putative 0.0076 0.0342 0.1242
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0052 0.0183 0.0645
Echinococcus granulosus subfamily T1A non peptidase ue 0.0258 0.1517 0.3793
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0148 0.0806 0.2016
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0326 0.1958 0.2091
Loa Loa (eye worm) heterochromatin protein 1 0.0143 0.0777 0.0947
Mycobacterium ulcerans glutaminase 0.0274 0.1622 0.4495
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0224 0.0224
Schistosoma mansoni phd/f-box containing protein 0.0079 0.0362 0.0905
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0054 0.0199 0.0497
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0035 0.0075 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0032
Brugia malayi proteasome subunit beta type 3 0.0227 0.1317 0.1605
Onchocerca volvulus 0.0024 0.0003 0.0003
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0174 0.0975 0.2698
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0036 0.0082 0.0298
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Trypanosoma brucei proteasome beta 6 subunit 0.0276 0.1638 0.5945
Brugia malayi proteasome subunit alpha type 6 0.0259 0.1528 0.1861
Trypanosoma brucei trypanothione reductase 0.0076 0.0342 0.1224
Loa Loa (eye worm) hypothetical protein 0.008 0.0369 0.0449
Brugia malayi 26S proteasome subunit P45 family protein 0.0036 0.0082 0.01
Echinococcus multilocularis geminin 0.0493 0.3041 0.3041
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.1253 0.1338
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0054 0.0199 0.0703
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0237 0.1385 0.1837
Onchocerca volvulus 0.1469 0.9365 1
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0227 0.1317 0.3293
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0257 0.0642
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0179 0.1008 0.3652
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0141 0.0763 0.1908
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0059 0.0231 0.0819
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0186 0.1051 0.1051
Onchocerca volvulus 0.0024 0.0003 0.0003
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0227 0.1317 0.3293
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0085 0.0091
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0038 0.0095 0.0238
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Loa Loa (eye worm) hypothetical protein 0.0186 0.1051 0.128
Brugia malayi NADH dehydrogenase subunit 1 0.0039 0.0098 0.012
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0217 0.1253 0.1642
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0258 0.1517 0.3793
Leishmania major proteasome beta 2 subunit, putative 0.0227 0.1317 0.4777
Onchocerca volvulus 0.0039 0.0098 0.0105
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0217 0.1253 0.4544

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 1.258925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (ADMET) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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