Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0095 | 0.0074 |
Echinococcus multilocularis | dna polymerase kappa | 0.0039 | 0.0169 | 0.0152 |
Loa Loa (eye worm) | TAR-binding protein | 0.02 | 0.2422 | 0.241 |
Schistosoma mansoni | tar DNA-binding protein | 0.02 | 0.2422 | 0.2533 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0039 | 0.0167 | 0.9569 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0039 | 0.0167 | 0.2606 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.029 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0101 | 0.0085 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0451 | 0.0436 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.2723 |
Schistosoma mansoni | tar DNA-binding protein | 0.02 | 0.2422 | 0.2533 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0414 | 0.5401 | 0.5682 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.5401 | 0.5394 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.004 | 0.018 | 0.0164 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0039 | 0.0169 | 0.1743 |
Echinococcus granulosus | geminin | 0.0707 | 0.9488 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0051 | 0.0332 | 0.0316 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0095 | 0.0079 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.0641 | 0.0626 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.0204 | 0.6756 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Mycobacterium tuberculosis | Probable reductase | 0.0109 | 0.1143 | 0.8519 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.0123 | 0.3702 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1111 | 0.1097 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0039 | 0.0169 | 1 |
Brugia malayi | Smad1 | 0.0051 | 0.0332 | 0.0316 |
Echinococcus multilocularis | smad | 0.0051 | 0.0332 | 0.0324 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.029 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0039 | 0.0167 | 0.5746 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0169 | 0.0152 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.004 | 0.018 | 0.0164 |
Schistosoma mansoni | DNA polymerase eta | 0.0039 | 0.0169 | 0.0152 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0039 | 0.0169 | 0.1743 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0192 | 0.23 | 0.2404 |
Schistosoma mansoni | hypothetical protein | 0.0707 | 0.9488 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.02 | 0.2422 | 0.241 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0192 | 0.23 | 0.2404 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.1595 | 0.1659 |
Brugia malayi | GH02984p | 0.0414 | 0.5401 | 0.5394 |
Brugia malayi | Sodium:solute symporter family protein | 0.0046 | 0.0262 | 0.0247 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0039 | 0.0169 | 0.0152 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.23 | 0.2404 |
Leishmania major | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.2723 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0109 | 0.0089 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.029 | 0.0275 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0095 | 0.0074 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0156 | 0.4936 |
Schistosoma mansoni | smad | 0.0051 | 0.0332 | 0.0324 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0123 | 0.1047 |
Schistosoma mansoni | inositol transporter | 0.0046 | 0.0262 | 0.025 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.0936 | 0.0962 |
Brugia malayi | Heterochromatin protein 1 | 0.0078 | 0.0708 | 0.0694 |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0332 | 0.0324 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0051 | 0.0332 | 0.0324 |
Brugia malayi | TAR-binding protein | 0.02 | 0.2422 | 0.241 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0046 | 0.0262 | 0.025 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0046 | 0.0262 | 0.025 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0046 | 0.0262 | 0.8928 |
Trichomonas vaginalis | rotamase, putative | 0.004 | 0.018 | 0.1913 |
Trichomonas vaginalis | rotamase, putative | 0.0039 | 0.0167 | 0.1713 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.1595 | 0.1582 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0169 | 0.0153 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0039 | 0.0169 | 0.2723 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0252 | 0.3134 | 0.3124 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0169 | 0.5813 |
Echinococcus multilocularis | Smad4 | 0.0051 | 0.0332 | 0.0324 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.029 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.1111 | 0.1097 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.0708 | 0.0722 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.2723 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0169 | 0.5813 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0025 | 0.0009 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.0708 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.0046 | 0.0262 | 0.025 |
Echinococcus multilocularis | geminin | 0.0707 | 0.9488 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0666 | 0.0678 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0109 | 0.0094 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0051 | 0.0332 | 0.0324 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.029 | 0.028 |
Leishmania major | DNA polymerase eta, putative | 0.0039 | 0.0169 | 0.2723 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0095 | 0.0074 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Loa Loa (eye worm) | RNA binding protein | 0.02 | 0.2422 | 0.241 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.0278 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0192 | 0.23 | 0.2287 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.029 | 0.1063 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0095 | 0.0074 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0169 | 0.0152 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0278 | 0.3419 |
Schistosoma mansoni | rotamase | 0.004 | 0.018 | 0.0164 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0232 | 0.2714 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.0073 | 0.0058 |
Brugia malayi | chromobox protein homolog 3 | 0.0044 | 0.0232 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0232 | 0.0217 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0123 | 0.1047 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0078 | 0.0708 | 0.0694 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.0708 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0641 | 0.0651 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0262 | 0.0247 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0095 | 0.0074 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.029 | 0.0275 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0046 | 0.0262 | 0.025 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.23 | 0.2404 |
Echinococcus multilocularis | dna polymerase eta | 0.0039 | 0.0169 | 0.0152 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0039 | 0.0167 | 0.2606 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.1595 | 0.1659 |
Trypanosoma brucei | unspecified product | 0.0039 | 0.0169 | 0.5813 |
Brugia malayi | RNA binding protein | 0.02 | 0.2422 | 0.241 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0095 | 0.0079 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.0123 | 0.0108 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0109 | 0.1143 | 0.8519 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.029 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0169 | 0.5813 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0095 | 0.0074 |
Schistosoma mansoni | inositol transporter | 0.0046 | 0.0262 | 0.025 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0046 | 0.0262 | 0.025 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.0204 | 0.2286 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.029 | 1 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.0073 | 0.0051 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0744 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0278 | 0.3419 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0039 | 0.0169 | 0.0153 |
Onchocerca volvulus | 0.0046 | 0.0262 | 0.9351 | |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0095 | 0.0074 |
Echinococcus granulosus | tar DNA binding protein | 0.02 | 0.2422 | 0.2533 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0192 | 0.23 | 0.2287 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0025 | 0.0009 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.1111 | 0.1097 |
Schistosoma mansoni | tar DNA-binding protein | 0.02 | 0.2422 | 0.2533 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.9007 | 0.9492 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0744 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0109 | 0.0089 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.0936 | 0.0962 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.0123 | 0.0104 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.0123 | 0.4247 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0109 | 0.1143 | 0.8519 |
Brugia malayi | MH2 domain containing protein | 0.0051 | 0.0332 | 0.0316 |
Echinococcus multilocularis | expressed protein | 0.004 | 0.018 | 0.0164 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0039 | 0.0167 | 0.2606 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0121 | 0.1312 | 1 |
Echinococcus granulosus | expressed protein | 0.004 | 0.018 | 0.0164 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.0708 | 0.0722 |
Echinococcus granulosus | dna polymerase kappa | 0.0039 | 0.0169 | 0.0152 |
Echinococcus granulosus | peregrin | 0.0032 | 0.0073 | 0.0051 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0156 | 0.9113 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.0204 | 0.6756 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0039 | 0.0169 | 0.2723 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.3134 | 0.3124 |
Leishmania major | trypanothione reductase | 0.0048 | 0.029 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0232 | 0.2714 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0095 | 0.0074 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.2723 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0123 | 0.1047 |
Echinococcus multilocularis | tar DNA binding protein | 0.02 | 0.2422 | 0.2533 |
Brugia malayi | MH1 domain containing protein | 0.0051 | 0.0332 | 0.0316 |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0332 | 0.0324 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0169 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.02 | 0.2422 | 0.2533 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0095 | 0.0079 |
Schistosoma mansoni | tar DNA-binding protein | 0.02 | 0.2422 | 0.2533 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.0169 | 0.0153 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0109 | 0.1143 | 0.8519 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0109 | 0.0094 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0095 | 0.0074 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.0123 | 0.3702 |
Echinococcus granulosus | solute carrier family 5 | 0.0046 | 0.0262 | 0.025 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0121 | 0.1312 | 1 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.0123 | 0.0104 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.02 | 0.2422 | 0.241 |
Schistosoma mansoni | sodium/solute symporter | 0.0046 | 0.0262 | 0.025 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0051 | 0.0332 | 0.0324 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.029 | 0.0275 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0414 | 0.5401 | 0.5682 |
Echinococcus granulosus | dna polymerase eta | 0.0039 | 0.0169 | 0.0152 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0232 | 0.8179 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0169 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.23 | 0.2404 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.0936 | 0.0921 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.0708 | 0.0722 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0036 | 0.0123 | 0.3702 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0641 | 0.0626 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.9007 | 0.9492 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0311 | 0.0296 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0051 | 0.0332 | 0.0324 |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0332 | 0.0324 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0095 | 0.0079 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.0708 | 0.0722 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0121 | 0.1312 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0051 | 0.0332 | 0.0316 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0009 |
Onchocerca volvulus | 0.0034 | 0.0101 | 0.2998 | |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.154 | 0.1601 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.0708 | 0.0722 |
Schistosoma mansoni | high-affinity choline transporter | 0.0414 | 0.5401 | 0.5682 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.0123 | 0.0104 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0121 | 0.1312 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0707 | 0.9488 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0095 | 0.0074 |
Brugia malayi | MH1 domain containing protein | 0.0051 | 0.0332 | 0.0316 |
Schistosoma mansoni | Smad4 | 0.0051 | 0.0332 | 0.0324 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.9007 | 0.9492 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0046 | 0.0262 | 0.025 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0039 | 0.0167 | 0.5343 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.018 | 0.1913 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0192 | 0.23 | 0.2404 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0156 | 0.7197 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0109 | 0.1143 | 0.8519 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.2723 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.0204 | 0.0189 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0039 | 0.0169 | 0.0152 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0046 | 0.0262 | 0.025 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.0123 | 0.0108 |
Brugia malayi | glutathione reductase | 0.0048 | 0.029 | 0.0275 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0182 | 0.0166 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.0204 | 0.2286 |
Echinococcus granulosus | smad | 0.0051 | 0.0332 | 0.0324 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0109 | 0.0089 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.029 | 0.028 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.0169 | 0.0153 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.029 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.0708 | 0.0722 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0051 | 0.0332 | 0.0324 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0169 | 0.5813 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.1595 | 0.1582 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0046 | 0.0262 | 0.025 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.0204 | 0.6756 |
Echinococcus granulosus | Smad4 | 0.0051 | 0.0332 | 0.0324 |
Loa Loa (eye worm) | Smad1 | 0.0051 | 0.0332 | 0.0316 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0192 | 0.23 | 0.2404 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0109 | 0.0089 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0182 | 0.0166 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.029 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0051 | 0.0332 | 0.0316 |
Giardia lamblia | DINP protein human, muc B family | 0.0039 | 0.0169 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0109 | 0.1143 | 0.8519 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.1111 | 0.1097 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0039 | 0.0169 | 0.5813 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
permeability (ADMET) | = 9 % | Permeability across brain in Tg2576 mouse at 100 mg/kg, po | ChEMBL. | 20880704 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.