Detailed information for compound 1247726

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 444.382 | Formula: C22H16F4N4O2
  • H donors: 1 H acceptors: 2 LogP: 4 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(Oc1ccc(cc1)[C@@]1(N=C(N(C1=O)C)N)c1cccc(c1)c1cc(F)cnc1F)F
  • InChi: 1S/C22H16F4N4O2/c1-30-19(31)22(29-21(30)27,13-5-7-16(8-6-13)32-20(25)26)14-4-2-3-12(9-14)17-10-15(23)11-28-18(17)24/h2-11,20H,1H3,(H2,27,29)/t22-/m1/s1
  • InChiKey: MOACUBOFXBSLGO-JOCHJYFZSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus GPCR family 2 0.0034 0.0095 0.0074
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0169 0.0152
Loa Loa (eye worm) TAR-binding protein 0.02 0.2422 0.241
Schistosoma mansoni tar DNA-binding protein 0.02 0.2422 0.2533
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0167 0.9569
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0167 0.2606
Plasmodium vivax glutathione reductase, putative 0.0048 0.029 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0101 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0451 0.0436
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0169 0.2723
Schistosoma mansoni tar DNA-binding protein 0.02 0.2422 0.2533
Echinococcus granulosus high affinity choline transporter 1 0.0414 0.5401 0.5682
Loa Loa (eye worm) hypothetical protein 0.0414 0.5401 0.5394
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.018 0.0164
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0169 0.1743
Echinococcus granulosus geminin 0.0707 0.9488 1
Brugia malayi MH2 domain containing protein 0.0051 0.0332 0.0316
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0095 0.0079
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0641 0.0626
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0204 0.6756
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Mycobacterium tuberculosis Probable reductase 0.0109 0.1143 0.8519
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0123 0.3702
Loa Loa (eye worm) hypothetical protein 0.0107 0.1111 0.1097
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0169 1
Brugia malayi Smad1 0.0051 0.0332 0.0316
Echinococcus multilocularis smad 0.0051 0.0332 0.0324
Trypanosoma brucei trypanothione reductase 0.0048 0.029 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0167 0.5746
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0169 0.0152
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.018 0.0164
Schistosoma mansoni DNA polymerase eta 0.0039 0.0169 0.0152
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0169 0.1743
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.23 0.2404
Schistosoma mansoni hypothetical protein 0.0707 0.9488 1
Brugia malayi RNA recognition motif domain containing protein 0.02 0.2422 0.241
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.23 0.2404
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.1595 0.1659
Brugia malayi GH02984p 0.0414 0.5401 0.5394
Brugia malayi Sodium:solute symporter family protein 0.0046 0.0262 0.0247
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0169 0.0152
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.23 0.2404
Leishmania major DNA polymerase kappa, putative 0.0039 0.0169 0.2723
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0109 0.0089
Brugia malayi Thioredoxin reductase 0.0048 0.029 0.0275
Echinococcus multilocularis GPCR, family 2 0.0034 0.0095 0.0074
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0156 0.4936
Schistosoma mansoni smad 0.0051 0.0332 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0123 0.1047
Schistosoma mansoni inositol transporter 0.0046 0.0262 0.025
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0936 0.0962
Brugia malayi Heterochromatin protein 1 0.0078 0.0708 0.0694
Schistosoma mansoni smad1 5 8 and 0.0051 0.0332 0.0324
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.0332 0.0324
Brugia malayi TAR-binding protein 0.02 0.2422 0.241
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0046 0.0262 0.025
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0046 0.0262 0.025
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0046 0.0262 0.8928
Trichomonas vaginalis rotamase, putative 0.004 0.018 0.1913
Trichomonas vaginalis rotamase, putative 0.0039 0.0167 0.1713
Loa Loa (eye worm) acetyltransferase 0.0141 0.1595 0.1582
Loa Loa (eye worm) hypothetical protein 0.0039 0.0169 0.0153
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0169 0.2723
Brugia malayi photoreceptor-specific nuclear receptor 0.0252 0.3134 0.3124
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0169 0.5813
Echinococcus multilocularis Smad4 0.0051 0.0332 0.0324
Plasmodium falciparum thioredoxin reductase 0.0048 0.029 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.1111 0.1097
Schistosoma mansoni chromobox protein 0.0078 0.0708 0.0722
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0169 0.2723
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0169 0.5813
Brugia malayi PHD-finger family protein 0.0029 0.0025 0.0009
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0708 1
Echinococcus multilocularis solute carrier family 5 0.0046 0.0262 0.025
Echinococcus multilocularis geminin 0.0707 0.9488 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0666 0.0678
Brugia malayi jmjC domain containing protein 0.0035 0.0109 0.0094
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.0332 0.0324
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.029 0.028
Leishmania major DNA polymerase eta, putative 0.0039 0.0169 0.2723
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Loa Loa (eye worm) RNA binding protein 0.02 0.2422 0.241
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0278 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.23 0.2287
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.029 0.1063
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0074
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0169 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0278 0.3419
Schistosoma mansoni rotamase 0.004 0.018 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0232 0.2714
Brugia malayi Bromodomain containing protein 0.0032 0.0073 0.0058
Brugia malayi chromobox protein homolog 3 0.0044 0.0232 0.0217
Loa Loa (eye worm) hypothetical protein 0.0044 0.0232 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0123 0.1047
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0708 0.0694
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0708 1
Schistosoma mansoni hypothetical protein 0.0073 0.0641 0.0651
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0247
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0095 0.0074
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.029 0.0275
Echinococcus granulosus sodium:glucose cotransporter 0.0046 0.0262 0.025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.23 0.2404
Echinococcus multilocularis dna polymerase eta 0.0039 0.0169 0.0152
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0167 0.2606
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.1595 0.1659
Trypanosoma brucei unspecified product 0.0039 0.0169 0.5813
Brugia malayi RNA binding protein 0.02 0.2422 0.241
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0095 0.0079
Brugia malayi beta-NAC-like protein 0.0036 0.0123 0.0108
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1143 0.8519
Plasmodium falciparum glutathione reductase 0.0048 0.029 1
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0169 0.5813
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0074
Schistosoma mansoni inositol transporter 0.0046 0.0262 0.025
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0046 0.0262 0.025
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0204 0.2286
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.029 1
Echinococcus multilocularis peregrin 0.0032 0.0073 0.0051
Loa Loa (eye worm) transcription factor SMAD2 0.0744 1 1
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0278 0.3419
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0169 0.0153
Onchocerca volvulus 0.0046 0.0262 0.9351
Schistosoma mansoni hypothetical protein 0.0034 0.0095 0.0074
Echinococcus granulosus tar DNA binding protein 0.02 0.2422 0.2533
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.23 0.2287
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0025 0.0009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.1111 0.1097
Schistosoma mansoni tar DNA-binding protein 0.02 0.2422 0.2533
Echinococcus multilocularis microtubule associated protein 2 0.0672 0.9007 0.9492
Loa Loa (eye worm) MH2 domain-containing protein 0.0744 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0109 0.0089
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0936 0.0962
Echinococcus multilocularis transcription factor btf3 0.0036 0.0123 0.0104
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0123 0.4247
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1143 0.8519
Brugia malayi MH2 domain containing protein 0.0051 0.0332 0.0316
Echinococcus multilocularis expressed protein 0.004 0.018 0.0164
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0167 0.2606
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1312 1
Echinococcus granulosus expressed protein 0.004 0.018 0.0164
Echinococcus multilocularis chromobox protein 1 0.0078 0.0708 0.0722
Echinococcus granulosus dna polymerase kappa 0.0039 0.0169 0.0152
Echinococcus granulosus peregrin 0.0032 0.0073 0.0051
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0156 0.9113
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0204 0.6756
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0169 0.2723
Loa Loa (eye worm) hypothetical protein 0.0252 0.3134 0.3124
Leishmania major trypanothione reductase 0.0048 0.029 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0232 0.2714
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0095 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0169 0.2723
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0123 0.1047
Echinococcus multilocularis tar DNA binding protein 0.02 0.2422 0.2533
Brugia malayi MH1 domain containing protein 0.0051 0.0332 0.0316
Schistosoma mansoni smad1 5 8 and 0.0051 0.0332 0.0324
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0169 0.5
Schistosoma mansoni tar DNA-binding protein 0.02 0.2422 0.2533
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0079
Schistosoma mansoni tar DNA-binding protein 0.02 0.2422 0.2533
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0169 0.0153
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1143 0.8519
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0109 0.0094
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0095 0.0074
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0123 0.3702
Echinococcus granulosus solute carrier family 5 0.0046 0.0262 0.025
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1312 1
Echinococcus granulosus transcription factor btf3 0.0036 0.0123 0.0104
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.2422 0.241
Schistosoma mansoni sodium/solute symporter 0.0046 0.0262 0.025
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.0332 0.0324
Loa Loa (eye worm) glutathione reductase 0.0048 0.029 0.0275
Echinococcus multilocularis high affinity choline transporter 1 0.0414 0.5401 0.5682
Echinococcus granulosus dna polymerase eta 0.0039 0.0169 0.0152
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0232 0.8179
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0169 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.23 0.2404
Brugia malayi jmjC domain containing protein 0.0094 0.0936 0.0921
Echinococcus multilocularis chromobox protein 1 0.0078 0.0708 0.0722
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0123 0.3702
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Loa Loa (eye worm) hypothetical protein 0.0073 0.0641 0.0626
Echinococcus granulosus microtubule associated protein 2 0.0672 0.9007 0.9492
Loa Loa (eye worm) hypothetical protein 0.0049 0.0311 0.0296
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.0332 0.0324
Schistosoma mansoni smad1 5 8 and 0.0051 0.0332 0.0324
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0095 0.0079
Echinococcus granulosus chromobox protein 1 0.0078 0.0708 0.0722
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1312 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0332 0.0316
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0009
Onchocerca volvulus 0.0034 0.0101 0.2998
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.154 0.1601
Schistosoma mansoni chromobox protein 0.0078 0.0708 0.0722
Schistosoma mansoni high-affinity choline transporter 0.0414 0.5401 0.5682
Schistosoma mansoni transcription factor btf3 0.0036 0.0123 0.0104
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1312 1
Schistosoma mansoni hypothetical protein 0.0707 0.9488 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0095 0.0074
Brugia malayi MH1 domain containing protein 0.0051 0.0332 0.0316
Schistosoma mansoni Smad4 0.0051 0.0332 0.0324
Schistosoma mansoni microtubule-associated protein tau 0.0672 0.9007 0.9492
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0046 0.0262 0.025
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0167 0.5343
Trichomonas vaginalis conserved hypothetical protein 0.004 0.018 0.1913
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.23 0.2404
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0156 0.7197
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1143 0.8519
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0169 0.2723
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0204 0.0189
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0169 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Echinococcus granulosus sodium:glucose cotransporter 2 0.0046 0.0262 0.025
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0123 0.0108
Brugia malayi glutathione reductase 0.0048 0.029 0.0275
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0182 0.0166
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0204 0.2286
Echinococcus granulosus smad 0.0051 0.0332 0.0324
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0109 0.0089
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.029 0.028
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0169 0.0153
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.029 1
Echinococcus granulosus chromobox protein 1 0.0078 0.0708 0.0722
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.0332 0.0324
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0169 0.5813
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.1595 0.1582
Echinococcus granulosus sodium:myo inositol cotransporter 0.0046 0.0262 0.025
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0204 0.6756
Echinococcus granulosus Smad4 0.0051 0.0332 0.0324
Loa Loa (eye worm) Smad1 0.0051 0.0332 0.0316
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.23 0.2404
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0109 0.0089
Echinococcus granulosus jumonji domain containing protein 0.004 0.0182 0.0166
Toxoplasma gondii thioredoxin reductase 0.0048 0.029 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0332 0.0316
Giardia lamblia DINP protein human, muc B family 0.0039 0.0169 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1143 0.8519
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.1111 0.1097
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0169 0.5813

Activities

Activity type Activity value Assay description Source Reference
permeability (ADMET) = 9 % Permeability across brain in Tg2576 mouse at 100 mg/kg, po ChEMBL. 20880704

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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