Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) ligand 5 | Starlite/ChEMBL | References |
Homo sapiens | chemokine (C-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | heat shock protein 90, putative | 0.0046 | 0.2152 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Echinococcus granulosus | heat shock protein | 0.0046 | 0.2152 | 0.6782 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3173 | 1 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0031 | 0.1256 | 0.1256 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0183 | 1 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0046 | 0.2152 | 0.2242 |
Trichomonas vaginalis | heat shock protein, putative | 0.0044 | 0.1988 | 0.8533 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 0.9066 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.1342 | 0.1342 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3173 | 0.3173 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 0.9066 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0044 | 0.1988 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.1342 | 0.4229 |
Echinococcus multilocularis | heat shock protein 90 | 0.004 | 0.1766 | 0.5567 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.004 | 0.1766 | 0.5567 |
Schistosoma mansoni | heat shock protein | 0.0031 | 0.1256 | 0.3588 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.1342 | 0.3834 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0044 | 0.1988 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.1342 | 0.4229 |
Trichomonas vaginalis | endoplasmin, putative | 0.0034 | 0.142 | 0.345 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3173 | 0.3173 |
Loa Loa (eye worm) | endoplasmin | 0.0046 | 0.2152 | 0.2152 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.1342 | 0.1342 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.5359 | 0.5359 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0031 | 0.1256 | 0.3958 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.5359 | 0.5359 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.5359 | 0.5359 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.5359 | 0.5359 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0176 | 0.96 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.1342 | 0.3834 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3173 | 0.3173 |
Schistosoma mansoni | heat shock protein | 0.0046 | 0.2152 | 0.6149 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.2152 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.1342 | 0.4229 |
Echinococcus granulosus | heat shock protein 90 | 0.004 | 0.1766 | 0.5567 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Schistosoma mansoni | endoplasmin | 0.0046 | 0.2152 | 0.6149 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.35 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.2152 | 1 |
Brugia malayi | heat shock protein 90 | 0.0046 | 0.2152 | 0.2152 |
Plasmodium falciparum | endoplasmin, putative | 0.0034 | 0.142 | 0.045 |
Echinococcus multilocularis | endoplasmin | 0.0044 | 0.1988 | 0.6265 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.1342 | 0.4229 |
Treponema pallidum | heat shock protein 90 | 0.0044 | 0.1988 | 0.5 |
Echinococcus granulosus | endoplasmin | 0.0044 | 0.1988 | 0.6265 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.1342 | 0.4229 |
Echinococcus multilocularis | heat shock protein 90 | 0.0046 | 0.2152 | 0.6782 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.004 | 0.1766 | 0.7515 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.1342 | 0.3834 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Schistosoma mansoni | heat shock protein | 0.0046 | 0.2152 | 0.6149 |
Giardia lamblia | Grp94/Hsp90 | 0.0044 | 0.1988 | 0.5748 |
Trypanosoma cruzi | heat shock protein, putative | 0.0031 | 0.1256 | 0.4226 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3173 | 0.3173 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0031 | 0.1256 | 0.3958 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.1766 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3173 | 0.3173 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0044 | 0.1988 | 0.817 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0046 | 0.2152 | 1 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0046 | 0.2152 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0046 | 0.2152 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0046 | 0.2152 | 1 |
Plasmodium vivax | endoplasmin, putative | 0.0046 | 0.2152 | 0.1074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 0.9066 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0031 | 0.1256 | 0.1256 |
Brugia malayi | Endoplasmin precursor | 0.0046 | 0.2152 | 0.2152 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0046 | 0.2152 | 0.2152 |
Schistosoma mansoni | endoplasmin | 0.0046 | 0.2152 | 0.6149 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3173 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3173 | 0.3173 |
Plasmodium vivax | heat shock protein 86, putative | 0.0046 | 0.2152 | 0.1074 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0046 | 0.2152 | 0.2242 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.004 | 0.1766 | 0.7515 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0046 | 0.2152 | 0.1305 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.1342 | 0.1342 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0034 | 0.142 | 0.345 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.1342 | 0.3834 |
Echinococcus granulosus | heat shock protein 90 | 0.0046 | 0.2152 | 0.6782 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0031 | 0.1256 | 0.1308 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0044 | 0.1988 | 0.5 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0176 | 0.96 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0046 | 0.2152 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0046 | 0.2152 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.1342 | 0.4229 |
Echinococcus multilocularis | heat shock protein | 0.0046 | 0.2152 | 0.6782 |
Trichomonas vaginalis | heat shock protein, putative | 0.0044 | 0.1988 | 0.8533 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0044 | 0.1988 | 0.5 |
Plasmodium vivax | heat shock protein, putative | 0.0176 | 0.96 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.35 | 0.35 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.1342 | 0.1342 |
Brugia malayi | Hsp90 protein | 0.0031 | 0.1256 | 0.1256 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.2152 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.2152 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 0.9066 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.35 | 0.35 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 0.9066 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0046 | 0.2152 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.2152 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.