Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 1 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0 | 0.5 |
Trypanosoma brucei | unspecified product | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0071 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 20850977 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.