Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | dihydrolipoamide S-acetyltransferase | 0.0106 | 0.0264 | 0.0263 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0069 | 0.0072 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0083 | 0.0084 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.3034 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0052 | 0.0083 | 0.0084 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0083 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0002 |
Mycobacterium leprae | ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 | 0.0411 | 0.1278 | 0.327 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0121 | 0.0313 | 0.0767 |
Chlamydia trachomatis | acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | 0.0411 | 0.1278 | 0.3696 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0052 | 0.0083 | 0.2246 |
Onchocerca volvulus | 0.0051 | 0.0079 | 0.2121 | |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.3034 | 1 | 1 |
Schistosoma mansoni | pyruvate carboxylase | 0.1156 | 0.3754 | 0.3753 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0239 | 0.0704 | 0.073 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.2196 | 0.7212 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0099 | 0.0239 | 0.0171 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0239 | 0.0704 | 0.0703 |
Leishmania major | carboxylase, putative | 0.1156 | 0.3754 | 0.371 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0034 | 0.0035 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0121 | 0.0313 | 0.0767 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0321 | 0.0979 | 0.1505 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.1156 | 0.3754 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0062 | 0.0116 | 0.0055 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0051 | 0.0079 | 0.0078 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.1156 | 0.3754 | 0.371 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0058 | 0.0103 | 0.0101 |
Loa Loa (eye worm) | methionyl-tRNA synthetase | 0.0056 | 0.0097 | 0.0101 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0329 | 0.1006 | 0.1005 |
Echinococcus granulosus | dihydrolipoyllysine residue acetyltransferase | 0.0106 | 0.0264 | 0.0263 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0058 | 0.0103 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0088 | 0.0091 |
Toxoplasma gondii | acyl-CoA carboxyltransferase beta chain, putative | 0.0411 | 0.1278 | 0.1217 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0083 | 0.0084 |
Toxoplasma gondii | 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein | 0.0106 | 0.0264 | 0.0196 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0152 | 0.0416 | 0.0357 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.1156 | 0.3754 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0239 | 0.0704 | 0.0703 |
Schistosoma mansoni | hypothetical protein | 0.0312 | 0.0949 | 0.0947 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4 | 0.0411 | 0.1278 | 0.3345 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0099 | 0.0239 | 0.7849 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0083 | 0.0084 |
Plasmodium falciparum | methionine--tRNA ligase | 0.0056 | 0.0097 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0034 | 0.0035 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0052 | 0.0083 | 0.0086 |
Mycobacterium leprae | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB | 0.0106 | 0.0264 | 0.0514 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0083 | 0.0081 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0058 | 0.0103 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0411 | 0.1278 | 0.1996 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.011 | 0.0278 | 0.0276 |
Mycobacterium ulcerans | carbamoyl phosphate synthase large subunit | 0.0261 | 0.078 | 0.2005 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.1156 | 0.3754 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.0203 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0264 | 0.0274 |
Leishmania major | dihydrolipoamide acetyltransferase precursorlike protein | 0.0106 | 0.0264 | 0.0196 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.2196 | 0.7212 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0052 | 0.0083 | 0.0081 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.0123 | 0.0122 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.2928 | 0.9647 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0083 | 0.0081 |
Plasmodium falciparum | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 0.0106 | 0.0264 | 0.0321 |
Plasmodium falciparum | dihydrolipoamide acyltransferase component E2 | 0.0106 | 0.0264 | 0.0321 |
Echinococcus granulosus | geminin | 0.0167 | 0.0467 | 0.0466 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0264 | 0.0274 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0261 | 0.078 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0075 | 0.0078 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0075 | 0.0112 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0109 | 0.0272 | 0.0658 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.0075 | 0.0112 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.011 | 0.0278 | 0.0673 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0083 | 0.0081 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.1156 | 0.3754 | 0.3716 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0052 | 0.0083 | 0.0081 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0083 | 0.0081 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0123 | 0.0122 |
Trypanosoma cruzi | glutamine-dependent carbamoyl-phosphate synthetase, putative | 0.0261 | 0.078 | 0.1179 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0051 | 0.0079 | 0.0082 |
Entamoeba histolytica | hypothetical protein | 0.0182 | 0.0517 | 0.2841 |
Mycobacterium ulcerans | dihydrolipoamide acetyltransferase | 0.0106 | 0.0264 | 0.062 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0075 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0123 | 0.0122 |
Echinococcus multilocularis | methionine tRNA synthetase | 0.0056 | 0.0097 | 0.0096 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0278 | 0.0276 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.1878 | 0.6157 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0069 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0123 | 0.0122 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0239 | 0.0704 | 0.0703 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0261 | 0.078 | 0.0778 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.0161 | 0.016 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0083 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0052 | 0.0083 | 0.0081 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0062 | 0.0116 | 0.012 |
Wolbachia endosymbiont of Brugia malayi | Acetyl-CoA carboxylase, carboxyltransferase component | 0.0411 | 0.1278 | 0.323 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.1156 | 0.3754 | 0.3753 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0069 | 0.0014 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0052 | 0.0083 | 0.2246 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0083 | 0.0086 |
Mycobacterium tuberculosis | DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase | 0.0106 | 0.0264 | 0.0637 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0075 | 0.0006 |
Plasmodium falciparum | carbamoyl phosphate synthetase | 0.0261 | 0.078 | 0.1039 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0034 | 0.0035 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.0075 | 0.0112 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0106 | 0.0264 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0079 | 0.0082 |
Trichomonas vaginalis | esterase, putative | 0.011 | 0.0278 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0169 | 0.0473 | 0.1182 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.0123 | 0.0128 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0079 | 0.0081 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0321 | 0.0979 | 0.1505 |
Mycobacterium tuberculosis | Probable branched-chain keto acid dehydrogenase E2 component BkdC | 0.0106 | 0.0264 | 0.0637 |
Mycobacterium ulcerans | hypothetical protein | 0.011 | 0.0278 | 0.0656 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.1156 | 0.3754 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0051 | 0.0079 | 0.2121 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.1156 | 0.3754 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0069 | 0.005 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0106 | 0.0264 | 0.0333 |
Mycobacterium ulcerans | lipase LipD | 0.011 | 0.0278 | 0.0656 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0083 | 0.0081 |
Plasmodium vivax | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative | 0.0106 | 0.0264 | 0.0321 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0411 | 0.1278 | 0.1996 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.3034 | 1 | 1 |
Brugia malayi | dihydrolipoamide S-acetyltransferase precursor, putative | 0.0106 | 0.0264 | 0.0272 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0069 | 0.0072 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0052 | 0.0083 | 0.0081 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0062 | 0.0116 | 0.0047 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0239 | 0.0704 | 0.0703 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0321 | 0.0979 | 0.0923 |
Schistosoma mansoni | coup transcription factor | 0.0052 | 0.0083 | 0.0081 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0182 | 0.0517 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0051 | 0.0079 | 0.0078 |
Entamoeba histolytica | hypothetical protein | 0.0182 | 0.0517 | 0.2841 |
Mycobacterium ulcerans | acetyl-/propionyl-CoA carboxylase subunit beta | 0.0411 | 0.1278 | 0.3345 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.0116 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Trypanosoma brucei | glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative | 0.0261 | 0.078 | 0.0723 |
Brugia malayi | nuclear receptor NHR-88 | 0.0052 | 0.0083 | 0.0084 |
Mycobacterium tuberculosis | Probable reductase | 0.0109 | 0.0272 | 0.0658 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0075 | 0.0006 |
Mycobacterium tuberculosis | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) | 0.0056 | 0.0097 | 0.0188 |
Plasmodium vivax | carbamoyl phosphate synthetase, putative | 0.0261 | 0.078 | 0.1039 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0123 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0075 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0083 | 0.0084 |
Leishmania major | hypothetical protein, conserved | 0.011 | 0.0278 | 0.021 |
Trypanosoma brucei | hypothetical protein, conserved | 0.011 | 0.0278 | 0.0218 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0705 | 0.2255 | 0.5978 |
Brugia malayi | steroid hormone receptor | 0.0052 | 0.0083 | 0.0084 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0052 | 0.0083 | 0.0081 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0052 | 0.0083 | 0.0086 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0121 | 0.0313 | 0.0767 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0083 | 0.0086 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0075 | 0.0076 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0069 | 0.007 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.011 | 0.0278 | 0.0656 |
Onchocerca volvulus | 0.0049 | 0.0075 | 0.1951 | |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0121 | 0.0313 | 0.0646 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0083 | 0.0084 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0083 | 0.0084 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0058 | 0.0103 | 0.0101 |
Echinococcus granulosus | Biotin lipoyl attachment | 0.0106 | 0.0264 | 0.0263 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0055 | 0.0094 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0047 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Mycobacterium tuberculosis | Probable hydrolase | 0.011 | 0.0278 | 0.0673 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.1156 | 0.3754 | 0.6058 |
Onchocerca volvulus | 0.011 | 0.0278 | 1 | |
Brugia malayi | Carboxyl transferase domain containing protein | 0.2928 | 0.9647 | 1 |
Mycobacterium tuberculosis | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 | 0.0411 | 0.1278 | 0.3357 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0062 | 0.0116 | 0.0114 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0278 | 0.0356 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0062 | 0.0116 | 0.0089 |
Brugia malayi | Bromodomain containing protein | 0.0049 | 0.0073 | 0.0074 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0058 | 0.0103 | 0.0105 |
Trypanosoma brucei | 2-oxoglutarate dehydrogenase E2 component, putative | 0.0106 | 0.0264 | 0.0204 |
Leishmania major | methionyl-tRNA synthetase, putative | 0.0056 | 0.0097 | 0.0028 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0106 | 0.0264 | 0.0333 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.011 | 0.0278 | 0.0673 |
Echinococcus granulosus | zinc finger protein | 0.0029 | 0.0007 | 0.0005 |
Entamoeba histolytica | acetyl-coA carboxylase, putative | 0.0517 | 0.1632 | 1 |
Loa Loa (eye worm) | tyrosyl-tRNA synthetase | 0.0035 | 0.0026 | 0.0027 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0239 | 0.0704 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0034 | 0.0035 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0088 | 0.0204 | 0.0696 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0278 | 0.0673 |
Trypanosoma cruzi | acetyl-CoA carboxylase, putative | 0.0411 | 0.1278 | 0.1996 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0062 | 0.0116 | 0.0047 |
Trypanosoma brucei | pyruvate dehydrogenase complex E3 binding protein, putative | 0.0106 | 0.0264 | 0.0204 |
Echinococcus multilocularis | zinc finger protein | 0.0029 | 0.0007 | 0.0005 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0052 | 0.0083 | 0.0081 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0278 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0062 | 0.0116 | 0.0118 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0278 | 0.0673 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0079 | 0.0078 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0169 | 0.0473 | 0.1198 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0278 | 0.0356 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0052 | 0.0083 | 0.2246 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0088 | 0.0204 | 0.0828 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0069 | 0.0068 |
Leishmania major | carbamoyl-phosphate synthase, putative | 0.0261 | 0.078 | 0.0715 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0123 | 0.0122 |
Onchocerca volvulus | 0.0052 | 0.0083 | 0.2246 | |
Toxoplasma gondii | pyruvate carboxylase | 0.1156 | 0.3754 | 0.371 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0116 | 0.0114 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0148 | 0.0147 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.1156 | 0.3754 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.011 | 0.0278 | 0.0551 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0062 | 0.0116 | 0.012 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0182 | 0.0517 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Entamoeba histolytica | hypothetical protein | 0.0182 | 0.0517 | 0.2841 |
Mycobacterium leprae | Probable methionyl-tRNA synthase MetS | 0.0056 | 0.0097 | 0.006 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0062 | 0.0116 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0467 | 0.0466 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0239 | 0.0704 | 0.0703 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0204 | 0.0588 | 0.0587 |
Loa Loa (eye worm) | MBCTL1 | 0.0058 | 0.0103 | 0.0107 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0278 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0052 | 0.0083 | 0.0014 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 5 AccD5 | 0.0411 | 0.1278 | 0.3345 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0123 | 0.0122 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0062 | 0.0116 | 0.0114 |
Mycobacterium leprae | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) | 0.0411 | 0.1278 | 0.327 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0062 | 0.0116 | 0.0089 |
Echinococcus granulosus | propionyl coenzyme A carboxylase beta chain | 0.0411 | 0.1278 | 0.1277 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.011 | 0.0278 | 0.0288 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0083 | 0.0084 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0069 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0082 | 0.0084 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.0116 | 0.1019 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0027 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0278 | 0.0673 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0979 | 0.3167 | 0.3166 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.0075 | 0.0112 |
Leishmania major | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0411 | 0.1278 | 0.1217 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0278 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0069 | 0.005 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0088 | 0.0204 | 0.0237 |
Schistosoma mansoni | dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase | 0.0106 | 0.0264 | 0.0263 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0138 | 0.037 | 0.0382 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.0313 | 0.0325 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0051 | 0.0079 | 0.0078 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0038 | 0.0036 |
Mycobacterium leprae | Probable lipase LipE | 0.011 | 0.0278 | 0.0551 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0083 | 0.0081 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0069 | 0.007 |
Brugia malayi | Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor | 0.0106 | 0.0264 | 0.0272 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0278 | 1 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.1156 | 0.3754 | 0.3753 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0075 | 0.0112 |
Mycobacterium tuberculosis | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) | 0.0411 | 0.1278 | 0.3357 |
Toxoplasma gondii | carbamoylphosphate synthetase | 0.0261 | 0.078 | 0.0715 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0109 | 0.0272 | 0.0658 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.1156 | 0.3754 | 0.3716 |
Chlamydia trachomatis | dihydrolipoamide succinyltransferase | 0.0106 | 0.0264 | 0.0685 |
Trypanosoma cruzi | glutamine dependent carbamoyl-phosphate synthase, putative | 0.0261 | 0.078 | 0.1179 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0026 | 0.0025 |
Leishmania major | dihydrolipoamide branched chain transacylase, putative | 0.0106 | 0.0264 | 0.0196 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0123 | 0.0122 |
Mycobacterium leprae | Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) | 0.0411 | 0.1278 | 0.327 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0083 | 0.0081 |
Mycobacterium ulcerans | beta-lactamase | 0.011 | 0.0278 | 0.0656 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0106 | 0.0264 | 0.0333 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0278 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0204 | 0.0588 | 0.0587 |
Plasmodium vivax | hypothetical protein, conserved | 0.011 | 0.0278 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0264 | 0.0274 |
Onchocerca volvulus | 0.011 | 0.0278 | 1 | |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.3034 | 1 | 1 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.3034 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0075 | 0.0078 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0083 | 0.0086 |
Chlamydia trachomatis | dihydrolipoamide acetyltransferase | 0.0106 | 0.0264 | 0.0685 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0002 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0052 | 0.0083 | 0.0081 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.0116 | 0.1019 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0075 | 0.0076 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0202 | 0.0583 | 0.0602 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0123 | 0.0122 |
Echinococcus granulosus | dihydrolipoyllysine residue succinyltransferase | 0.0106 | 0.0264 | 0.0263 |
Loa Loa (eye worm) | beta-lactamase | 0.011 | 0.0278 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0467 | 0.0466 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0083 | 0.0086 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.0116 | 0.1019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0083 | 0.0086 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0099 | 0.0239 | 0.0171 |
Schistosoma mansoni | aspartate carbamoyltransferase | 0.0261 | 0.078 | 0.0778 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0058 | 0.0103 | 0.0101 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0329 | 0.1006 | 0.1042 |
Brugia malayi | nuclear hormone receptor | 0.0052 | 0.0083 | 0.0084 |
Trypanosoma brucei | dihydrolipoamide acetyltransferase E2 subunit, putative | 0.0106 | 0.0264 | 0.0204 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0148 | 0.0147 |
Echinococcus granulosus | FTZ F1 alpha | 0.0052 | 0.0083 | 0.0081 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0052 | 0.0083 | 0.0081 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0278 | 0.0286 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0109 | 0.0272 | 0.0658 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.0123 | 0.0122 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0079 | 0.0078 |
Mycobacterium ulcerans | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0106 | 0.0264 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.0313 | 0.0325 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.0313 | 0.0323 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0062 | 0.0116 | 0.0114 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.1156 | 0.3754 | 0.3753 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0062 | 0.0116 | 0.0047 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0083 | 0.0081 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0329 | 0.1006 | 0.1005 |
Echinococcus multilocularis | geminin | 0.0167 | 0.0467 | 0.0466 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.0123 | 0.0126 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.011 | 0.0278 | 0.0673 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0278 | 0.0276 |
Mycobacterium ulcerans | hypothetical protein | 0.0106 | 0.0264 | 0.062 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.0075 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0034 | 0.0035 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0052 | 0.0083 | 0.0081 |
Leishmania major | dihydrolipoamide acetyltransferase precursor, putative | 0.0106 | 0.0264 | 0.0196 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0083 | 0.0084 |
Brugia malayi | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta | 0.0106 | 0.0264 | 0.0272 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0083 | 0.0081 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.011 | 0.0278 | 0.0286 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0052 | 0.0083 | 0.0084 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase, putative | 0.0106 | 0.0264 | 0.0333 |
Toxoplasma gondii | dihydrolipoamide acyltransferase, putative | 0.0106 | 0.0264 | 0.0196 |
Brugia malayi | methionyl-tRNA synthetase | 0.0056 | 0.0097 | 0.0099 |
Wolbachia endosymbiont of Brugia malayi | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0106 | 0.0264 | 0.0457 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0109 | 0.0272 | 0.0658 |
Loa Loa (eye worm) | acetyltransferase | 0.0329 | 0.1006 | 0.1043 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.0517 | 0.0516 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0075 | 0.0006 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0079 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0583 | 0.0604 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0052 | 0.0083 | 0.0084 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0083 | 0.0084 |
Echinococcus multilocularis | Biotin lipoyl attachment | 0.0106 | 0.0264 | 0.0263 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0083 | 0.0086 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0062 | 0.0116 | 0.0114 |
Echinococcus multilocularis | dihydrolipoyllysine residue acetyltransferase | 0.0106 | 0.0264 | 0.0263 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.0075 | 0.0112 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0038 | 0.0036 |
Brugia malayi | hypothetical protein | 0.0182 | 0.0517 | 0.0535 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4_2 | 0.0411 | 0.1278 | 0.3345 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0056 | 0.0097 | 0.0096 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0052 | 0.0083 | 0.0081 |
Toxoplasma gondii | dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase | 0.0106 | 0.0264 | 0.0196 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.1156 | 0.3754 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0083 | 0.0084 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0062 | 0.0116 | 0.0089 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.0123 | 0.0126 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0062 | 0.0116 | 0.0055 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0099 | 0.0239 | 0.7849 |
Chlamydia trachomatis | dihydrolipoamide succinyltransferase | 0.0106 | 0.0264 | 0.0685 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0002 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0052 | 0.0083 | 0.0081 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide acyltransferase E2 component | 0.0106 | 0.0264 | 0.0457 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0052 | 0.0083 | 0.0081 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.1156 | 0.3754 | 1 |
Trypanosoma brucei | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0411 | 0.1278 | 0.1225 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0052 | 0.0083 | 0.0081 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.037 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Plasmodium falciparum | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.0106 | 0.0264 | 0.0321 |
Toxoplasma gondii | ABC1 family protein | 0.011 | 0.0278 | 0.021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0239 | 0.0704 | 0.0703 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0083 | 0.0081 |
Mycobacterium ulcerans | acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 | 0.0411 | 0.1278 | 0.3345 |
Leishmania major | propionyl-coa carboxylase beta chain, putative | 0.0411 | 0.1278 | 0.1217 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0083 | 0.0086 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.1156 | 0.3754 | 0.6058 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0202 | 0.0583 | 0.0604 |
Treponema pallidum | pyruvate carboxylase subunit B | 0.0106 | 0.0264 | 0.5 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0069 | 0.0008 |
Toxoplasma gondii | biotin-requiring enzyme domain-containing protein | 0.0106 | 0.0264 | 0.0196 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0052 | 0.0083 | 0.0081 |
Schistosoma mansoni | nuclear hormone receptor | 0.0052 | 0.0083 | 0.0081 |
Mycobacterium leprae | Probable biotinylated protein homolog TB7.3 | 0.0106 | 0.0264 | 0.0514 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.1156 | 0.3754 | 0.3753 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0056 | 0.0097 | 0.0088 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.011 | 0.0278 | 0.0276 |
Trypanosoma brucei | methionyl-tRNA synthetase, putative | 0.0056 | 0.0097 | 0.0036 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0052 | 0.0083 | 0.0081 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase beta chain | 0.0411 | 0.1278 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0123 | 0.0128 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0083 | 0.0084 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.011 | 0.0278 | 0.0656 |
Trypanosoma brucei | unspecified product | 0.076 | 0.2437 | 0.2391 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.011 | 0.0278 | 0.0673 |
Mycobacterium tuberculosis | Biotinylated protein TB7.3 | 0.0106 | 0.0264 | 0.0637 |
Chlamydia trachomatis | acetyl-CoA carboxylase biotin carboxyl carrier protein | 0.0106 | 0.0264 | 0.0685 |
Plasmodium vivax | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative | 0.0106 | 0.0264 | 0.0321 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.0075 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.037 | 0.0384 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0278 | 0.0286 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0069 | 0.0114 |
Brugia malayi | ecdysteroid receptor | 0.0052 | 0.0083 | 0.0084 |
Echinococcus multilocularis | dihydrolipoyllysine residue succinyltransferase | 0.0106 | 0.0264 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0103 | 0.0107 |
Brugia malayi | beta-lactamase | 0.011 | 0.0278 | 0.0286 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0106 | 0.0264 | 0.0263 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0106 | 0.0264 | 0.0333 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0182 | 0.0517 | 0.0516 |
Mycobacterium ulcerans | methionyl-tRNA synthetase | 0.0056 | 0.0097 | 0.0171 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0106 | 0.0264 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0161 | 0.0167 |
Schistosoma mansoni | propionyl-CoA carboxylase beta chain mitochondrial precursor | 0.0411 | 0.1278 | 0.1277 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0052 | 0.0083 | 0.0081 |
Trypanosoma cruzi | methionyl-tRNA synthetase, putative | 0.0056 | 0.0097 | 0.0059 |
Chlamydia trachomatis | biotin carboxylase | 0.1049 | 0.3401 | 1 |
Echinococcus granulosus | methionine tRNA synthetase | 0.0056 | 0.0097 | 0.0096 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0239 | 0.0704 | 0.0703 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0152 | 0.0416 | 0.0349 |
Schistosoma mansoni | zinc finger protein | 0.0029 | 0.0007 | 0.0005 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E2 | 0.0106 | 0.0264 | 0.0196 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0056 | 0.0097 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0083 | 0.0084 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.3034 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.0034 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0002 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0106 | 0.0264 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0278 | 0.0288 |
Wolbachia endosymbiont of Brugia malayi | carbamoyl phosphate synthase large subunit | 0.0261 | 0.078 | 0.1866 |
Giardia lamblia | Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative | 0.0517 | 0.1632 | 1 |
Onchocerca volvulus | 0.011 | 0.0278 | 1 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.011 | 0.0278 | 0.0673 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0099 | 0.0239 | 0.0286 |
Mycobacterium ulcerans | acetyl/propionyl CoA carboxylase subunit beta | 0.0411 | 0.1278 | 0.3345 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0051 | 0.0079 | 0.0078 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0321 | 0.0979 | 0.0916 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0069 | 0.005 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0109 | 0.0272 | 0.0658 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0318 | 0.0967 | 0.0966 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.0075 | 0.0129 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0109 | 0.0272 | 0.0536 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0202 | 0.0583 | 0.0602 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0075 | 0.0112 |
Leishmania major | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0106 | 0.0264 | 0.0196 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0052 | 0.0083 | 0.0084 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0099 | 0.0239 | 0.0237 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0152 | 0.0416 | 0.0583 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0051 | 0.0079 | 0.0078 |
Entamoeba histolytica | hypothetical protein | 0.0182 | 0.0517 | 0.2841 |
Trypanosoma brucei | dihydrolipoamide branched chain transacylase, putative | 0.0106 | 0.0264 | 0.0204 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.011 | 0.0278 | 0.0673 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 25.1189 um | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] | ChEMBL. | No reference |
Potency (functional) | 79.4328 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.