Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0064 | 0.0652 | 0.2054 |
Mycobacterium ulcerans | oxidoreductase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.004 | 0.0232 | 0.0109 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0195 | 0.0312 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0246 | 0.3873 | 0.6213 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.1637 | 0.392 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0081 | 0.0131 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.004 | 0.0232 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0058 | 0.0093 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0064 | 0.0652 | 0.1047 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.0903 | 0.1449 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0055 | 0.0488 | 0.0783 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0195 | 0.0312 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0064 | 0.0652 | 0.2054 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0168 | 0.2489 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0195 | 0.0345 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0055 | 0.0488 | 0.263 |
Trichomonas vaginalis | hypothetical protein | 0.0592 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0064 | 0.0652 | 0.0467 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0261 | 0.0418 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0178 | 0.0054 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0642 | 0.103 |
Schistosoma mansoni | tar DNA-binding protein | 0.0263 | 0.4176 | 0.67 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0195 | 0.0143 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0178 | 0.0054 |
Loa Loa (eye worm) | oxidoreductase | 0.004 | 0.0232 | 0.0372 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.1637 | 0.2626 |
Onchocerca volvulus | 0.0069 | 0.0744 | 0.1971 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.1289 | 0.2068 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0195 | 0.0143 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0178 | 0.0285 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1142 | 0.1832 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0178 | 0.0054 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.1142 | 0.1832 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0642 | 0.2009 |
Schistosoma mansoni | dihydropteridine reductase | 0.004 | 0.0232 | 0.0372 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0058 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.1806 | 0.2897 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.4927 | 0.7903 |
Trypanosoma brucei | oxidoreductase-like protein | 0.004 | 0.0232 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0534 | 0.0857 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0195 | 0.0312 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0081 | 0.0131 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.3938 | 0.6317 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0218 | 0.0349 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1142 | 0.1832 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0148 | 0.2141 | 0.3435 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0178 | 0.0125 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0058 | 0.0093 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0446 | 0.0715 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0147 | 0.2121 | 0.1978 |
Onchocerca volvulus | 0.0037 | 0.0178 | 0.0471 | |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0064 | 0.0652 | 0.4019 |
Brugia malayi | hypothetical protein | 0.0249 | 0.3938 | 0.9429 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0592 | 1 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.0411 | 0.066 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.0411 | 0.066 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0165 | 0.0264 |
Onchocerca volvulus | 0.0052 | 0.0446 | 0.1181 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1142 | 0.1832 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0195 | 0.0017 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0058 | 0.0005 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.1806 | 0.4785 |
Brugia malayi | hypothetical protein | 0.0151 | 0.22 | 0.5268 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0081 | 0.0131 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0724 | 0.1161 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.0534 | 0.0857 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0178 | 0.0285 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.0411 | 0.066 |
Echinococcus multilocularis | tar DNA binding protein | 0.0263 | 0.4176 | 0.67 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0165 | 0.0264 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0064 | 0.0652 | 0.0535 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0178 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Leishmania major | carboxylase, putative | 0.0064 | 0.0652 | 0.2054 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.103 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.004 | 0.0232 | 0.046 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.073 | 0.1748 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0053 | 0.0085 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0165 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0081 | 0.0131 |
Echinococcus granulosus | tar DNA binding protein | 0.0263 | 0.4176 | 0.67 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0053 | 0.0085 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0178 | 0.0054 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0232 | 0.0372 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.0473 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0411 | 0.0985 |
Loa Loa (eye worm) | hypothetical protein | 0.0379 | 0.6234 | 1 |
Leishmania major | oxidoreductase-like protein | 0.004 | 0.0232 | 0.0235 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0147 | 0.2121 | 0.2022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1142 | 0.1832 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.1806 | 0.4785 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1289 | 0.2068 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0232 | 0.0235 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.004 | 0.0232 | 0.0109 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0058 | 0.0093 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0411 | 0.066 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0081 | 0.0195 |
Echinococcus multilocularis | serotonin receptor | 0.0379 | 0.6234 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0592 | 1 | 1 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.004 | 0.0232 | 0.0372 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0081 | 0.0195 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0064 | 0.0652 | 0.1047 |
Onchocerca volvulus | 0.0051 | 0.0423 | 0.1121 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.2141 | 0.439 |
Leishmania major | stearic acid desaturase, putative | 0.0069 | 0.0744 | 0.2449 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.0473 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0232 | 0.0235 |
Onchocerca volvulus | 0.0069 | 0.0744 | 0.1971 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.1806 | 0.2897 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.0534 | 0.0857 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.03 | 0.4842 | 0.5 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0064 | 0.0652 | 0.0483 |
Brugia malayi | TAR-binding protein | 0.0263 | 0.4176 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0148 | 0.2141 | 0.3435 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0232 | 0.0372 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0165 | 0.0264 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0053 | 0.0127 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Schistosoma mansoni | tar DNA-binding protein | 0.0263 | 0.4176 | 0.67 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0218 | 0.0349 |
Onchocerca volvulus | 0.004 | 0.0232 | 0.0615 | |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0053 | 0.0085 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Echinococcus granulosus | peregrin | 0.003 | 0.0053 | 0.0085 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0121 | 0.1669 | 0.1625 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.03 | 0.4842 | 1 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0121 | 0.1669 | 0.1625 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0592 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0379 | 0.6234 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0379 | 0.6234 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0195 | 0.0017 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0379 | 0.6234 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0178 | 0.0054 |
Echinococcus granulosus | tumor protein p63 | 0.0356 | 0.5832 | 0.9355 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.22 | 0.3529 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0724 | 0.1161 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.004 | 0.0232 | 0.0109 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0081 | 0.0131 |
Loa Loa (eye worm) | RNA binding protein | 0.0263 | 0.4176 | 0.67 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0081 | 0.0131 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0211 | 0.3258 | 0.5226 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0724 | 0.1161 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0053 | 0.0127 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0592 | 1 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0178 | 0.0054 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0178 | 0.0285 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0109 |
Onchocerca volvulus | 0.0037 | 0.0178 | 0.0471 | |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0053 | 0.014 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0053 | 0.0085 |
Echinococcus multilocularis | serotonin receptor | 0.0379 | 0.6234 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.0534 | 0.0857 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0263 | 0.4176 | 0.67 |
Chlamydia trachomatis | biotin carboxylase | 0.0058 | 0.0549 | 0.0324 |
Schistosoma mansoni | hypothetical protein | 0.0148 | 0.2141 | 0.3435 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0165 | 0.0264 |
Loa Loa (eye worm) | TAR-binding protein | 0.0263 | 0.4176 | 0.67 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0109 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0178 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0162 | 0.2385 | 0.5712 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0261 | 0.0418 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0178 | 0.0125 |
Brugia malayi | hypothetical protein | 0.0148 | 0.2141 | 0.5127 |
Brugia malayi | hypothetical protein | 0.0129 | 0.1806 | 0.4323 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.004 | 0.0232 | 0.0055 |
Brugia malayi | follicle stimulating hormone receptor | 0.0246 | 0.3873 | 0.9274 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0068 | 0.0724 | 0.2363 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0198 | 0.3026 | 0.4854 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0178 | 0.0054 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.1142 | 0.2734 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0178 | 0.0054 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Trypanosoma brucei | pteridine reductase 1 | 0.004 | 0.0232 | 0.0235 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.004 | 0.0232 | 0.0109 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0178 | 0.0054 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0178 | 0.0425 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0069 | 0.0744 | 0.479 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0104 | 0.1359 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0263 | 0.4176 | 0.67 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0178 | 0.0054 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0053 | 0.0085 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.0534 | 0.1279 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0724 | 0.4622 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0411 | 0.066 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0055 | 0.0488 | 0.263 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0232 | 0.0372 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.0411 | 0.109 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0178 | 0.0285 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.126 | 0.3017 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.073 | 0.1171 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0165 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0432 | 0.0693 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0064 | 0.0652 | 0.0483 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1142 | 0.1832 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0064 | 0.0652 | 0.1047 |
Schistosoma mansoni | tar DNA-binding protein | 0.0263 | 0.4176 | 0.67 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0249 | 0.3938 | 0.6317 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0064 | 0.0652 | 0.1047 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0592 | 1 | 1 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.0411 | 0.066 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0064 | 0.0652 | 0.0483 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.2141 | 0.439 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0423 | 0.1013 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0148 | 0.2141 | 0.3435 |
Onchocerca volvulus | 0.0151 | 0.22 | 0.583 | |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0249 | 0.3938 | 0.6317 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1142 | 0.1832 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0178 | 0.0054 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0064 | 0.0652 | 0.0535 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.03 | 0.4842 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.004 | 0.0232 | 0.018 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0195 | 0.0073 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0081 | 0.0131 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.004 | 0.0232 | 0.0109 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1142 | 0.1832 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0168 | 0.2489 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.126 | 0.2022 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0232 | 0.0555 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0423 | 0.0678 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0195 | 0.0312 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0411 | 0.066 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0058 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0081 | 0.0131 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Onchocerca volvulus | 0.0037 | 0.0178 | 0.0471 | |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0178 | 0.0425 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0064 | 0.0652 | 0.0483 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0058 | 0.0093 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.004 | 0.0232 | 0.0109 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0064 | 0.0652 | 0.0535 |
Schistosoma mansoni | tar DNA-binding protein | 0.0263 | 0.4176 | 0.67 |
Onchocerca volvulus | 0.004 | 0.0232 | 0.0615 | |
Leishmania major | pteridine reductase 1 | 0.004 | 0.0232 | 0.0235 |
Trichomonas vaginalis | set domain proteins, putative | 0.024 | 0.3774 | 0.3661 |
Brugia malayi | acyl-CoA desaturase | 0.0055 | 0.0488 | 0.1169 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0168 | 0.2489 | 0.3993 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.1637 | 0.2626 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.0265 | 0.0379 |
Schistosoma mansoni | pyruvate carboxylase | 0.0064 | 0.0652 | 0.1047 |
Toxoplasma gondii | pyruvate carboxylase | 0.0064 | 0.0652 | 0.0603 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0724 | 0.2363 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0053 | 0.0085 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0109 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0195 | 0.0142 |
Echinococcus multilocularis | tumor protein p63 | 0.0356 | 0.5832 | 0.9355 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0411 | 0.0985 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.004 | 0.0232 | 0.018 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.126 | 0.2022 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0236 | 0.3709 | 0.363 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0081 | 0.0131 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0168 | 0.2489 | 0.2449 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0178 | 0.0285 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0168 | 0.2489 | 0.3993 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.046 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.2141 | 0.439 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0178 | 0.0285 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.004 | 0.0232 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0446 | 0.0715 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.0534 | 0.0857 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0058 | 0.0093 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0053 | 0.0085 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0058 | 0.0139 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.004 | 0.0232 | 0.0109 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0592 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0592 | 1 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Leishmania major | fatty-acid desaturase, putative | 0.0069 | 0.0744 | 0.2449 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0724 | 0.1161 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0195 | 0.0312 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0053 | 0.0051 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.004 | 0.0232 | 0.0372 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.1289 | 0.3087 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0038 | 0.0062 |
Onchocerca volvulus | 0.003 | 0.0058 | 0.0154 | |
Onchocerca volvulus | 0.005 | 0.0411 | 0.109 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0178 | 0.0425 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0081 | 0.0131 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0081 | 0.0131 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.0534 | 0.0857 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0058 | 0.0093 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0232 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.073 | 0.1171 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0195 | 0.0017 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0724 | 0.4622 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.004 | 0.0232 | 0.0423 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.0069 | 0.0744 | 0.2449 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0162 | 0.2385 | 0.3827 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.0473 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.0235 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0064 | 0.0652 | 0.2054 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.004 | 0.0232 | 0.0038 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0081 | 0.0131 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0168 | 0.2489 | 0.3993 |
Brugia malayi | RNA binding protein | 0.0263 | 0.4176 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.0592 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0068 | 0.0724 | 0.1733 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0068 | 0.0724 | 0.1445 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0232 | 0.0055 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.0524 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.004 | 0.0232 | 0.0109 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.0534 | 0.0857 |
Brugia malayi | Pre-SET motif family protein | 0.0211 | 0.3258 | 0.78 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0178 | 0.0285 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0232 | 0.0555 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0198 | 0.3026 | 0.4854 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0195 | 0.0073 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0195 | 0.0466 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0263 | 0.4176 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0195 | 0.0017 |
Onchocerca volvulus | 0.024 | 0.3774 | 1 | |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0055 | 0.0488 | 0.0438 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.0411 | 0.066 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.004 | 0.0232 | 0.018 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.004 | 0.0232 | 0.0235 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0232 | 0.046 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0618 | 0.0991 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.1289 | 0.3087 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0642 | 0.103 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0064 | 0.0652 | 0.4019 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.03 | 0.4842 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0058 | 0.0093 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0055 | 0.0488 | 0.0438 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0642 | 0.103 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.004 | 0.0232 | 0.018 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.0411 | 0.066 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.2141 | 0.439 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0423 | 0.0678 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0147 | 0.2121 | 0.2022 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 0.4842 | 0.4748 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0168 | 0.2489 | 0.2449 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | < 20 % | Antagonist activity against T-type calcium channel subunit alpha-1H assessed as inactivation of channel current at 3 uM by cell based patch clamp assay | ChEMBL. | 20934333 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.