Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0006 | 0.0015 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.1014 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0006 | 0.0096 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0016 | 0.017 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.1024 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0671 | 0.3887 | 0.3887 |
Echinococcus granulosus | tumor protein p63 | 0.0668 | 0.387 | 0.9957 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0006 | 0.0096 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0006 | 0.0006 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0056 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.021 | 0.054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0049 | 0.083 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0012 | 0.0016 | 0.2817 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0049 | 0.0741 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0006 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0016 | 0.017 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0006 | 0.0015 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0056 | 0.0937 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0056 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0592 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0006 | 0.0096 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.0394 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0102 | 0.0158 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0592 | 0.1524 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0522 | 0.8802 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0006 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0006 | 0.0015 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0102 | 0.136 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0056 | 0.0937 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0592 | 0.1524 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.011 | 0.0592 | 0.1339 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0006 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0049 | 0.0741 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0592 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0015 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0006 | 0.0096 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0049 | 0.8855 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0592 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0056 | 0.0143 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0006 | 0.0096 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0006 | 0.0096 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0049 | 0.0126 |
Mycobacterium ulcerans | beta-lactamase | 0.011 | 0.0592 | 0.1622 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0334 | 0.564 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.011 | 0.0592 | 0.1524 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0049 | 0.1247 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0006 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus granulosus | peptidase Clp S14 family | 0.005 | 0.024 | 0.0618 |
Trypanosoma brucei | hypothetical protein, conserved | 0.011 | 0.0592 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.011 | 0.0592 | 0.1504 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0102 | 0.1724 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0016 | 0.004 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0049 | 0.0741 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0102 | 0.1644 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0049 | 0.0126 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0012 | 0.0016 | 0.004 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0049 | 0.0049 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0049 | 0.1247 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0049 | 0.083 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0006 | 0.0015 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0102 | 0.2577 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0334 | 0.564 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0006 | 0.0006 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.021 | 0.021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0006 | 0.0006 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0056 | 0.0056 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0049 | 0.0126 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0701 | 0.4065 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0056 | 0.0143 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.011 | 0.0592 | 0.1339 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0006 | 0.0015 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.011 | 0.0592 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0049 | 0.0741 |
Brugia malayi | Probable ClpP-like protease | 0.0076 | 0.0394 | 0.6656 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.005 | 0.024 | 0.024 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.011 | 0.0592 | 0.1339 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0006 | 0.0096 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0006 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0056 | 0.0143 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0006 | 0.0096 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0049 | 0.083 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0251 | 0.4244 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0098 | 0.0522 | 0.1343 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.021 | 0.3543 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0016 | 0.0264 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0006 | 0.0096 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0049 | 0.0741 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.011 | 0.0592 | 0.1339 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0049 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0006 | 0.0096 |
Trichomonas vaginalis | esterase, putative | 0.011 | 0.0592 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0006 | 0.0096 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0592 | 1 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0006 | 0.0096 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0049 | 0.8855 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0006 | 0.0015 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0012 | 0.0016 | 0.0264 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0056 | 0.085 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0049 | 0.0049 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0056 | 0.0937 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Onchocerca volvulus | 0.0098 | 0.0522 | 0.8802 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0592 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0592 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0006 | 0.0096 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.011 | 0.0592 | 0.0592 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.0301 | 0.5074 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.005 | 0.024 | 0.0461 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0006 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 0.1024 |
Mycobacterium tuberculosis | Probable hydrolase | 0.011 | 0.0592 | 0.1339 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0049 | 0.0049 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0006 | 0.0006 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0006 | 0.0096 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0006 | 0.0015 |
Mycobacterium tuberculosis | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.0582 | 0.3364 | 0.8251 |
Toxoplasma gondii | pantoate-beta-alanine ligase | 0.0582 | 0.3364 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0049 | 0.8855 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.021 | 0.054 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0006 | 0.0096 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0076 | 0.0394 | 0.6656 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0056 | 0.1408 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Brugia malayi | beta-lactamase | 0.011 | 0.0592 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0334 | 0.564 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0016 | 0.0264 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.021 | 0.054 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0049 | 0.0741 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0006 | 0.0006 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0076 | 0.0394 | 0.0897 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.011 | 0.0592 | 0.1622 |
Mycobacterium leprae | Probable lipase LipE | 0.011 | 0.0592 | 0.1504 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0006 | 0.0015 |
Onchocerca volvulus | 0.011 | 0.0592 | 1 | |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.011 | 0.0592 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0006 | 0.0096 |
Mycobacterium ulcerans | pantoate--beta-alanine ligase | 0.0582 | 0.3364 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0671 | 0.3887 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.011 | 0.0592 | 0.1622 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0334 | 0.564 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0006 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0334 | 0.5246 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0056 | 0.0937 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0394 | 0.1041 |
Onchocerca volvulus | 0.011 | 0.0592 | 1 | |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0592 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0006 | 0.0096 |
Echinococcus multilocularis | tumor protein p63 | 0.0668 | 0.387 | 0.387 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0056 | 0.0937 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0592 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0016 | 0.017 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0394 | 0.1041 |
Plasmodium vivax | hypothetical protein, conserved | 0.011 | 0.0592 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0049 | 0.0741 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0006 | 0.0015 |
Brugia malayi | cathepsin L-like precursor | 0.0012 | 0.0016 | 0.0264 |
Onchocerca volvulus | 0.0012 | 0.0016 | 0.017 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.011 | 0.0592 | 0.1339 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0592 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.011 | 0.0592 | 0.1638 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0026 | 0.0102 | 0.1715 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0592 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0006 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0334 | 0.5246 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0076 | 0.0394 | 0.1014 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0592 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0006 | 0.0096 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0006 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.021 | 0.054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0049 | 0.1247 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0006 | 0.0015 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0056 | 0.0019 |
Mycobacterium leprae | Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.0582 | 0.3364 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0049 | 0.0741 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0592 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0016 | 0.0264 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.011 | 0.0592 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0049 | 0.0741 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.005 | 0.024 | 0.0461 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.021 | 0.021 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.021 | 0.348 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0006 | 0.0015 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | beta-lactamase | 0.011 | 0.0592 | 1 |
Onchocerca volvulus | 0.0017 | 0.0049 | 0.0741 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0006 | 0.0015 |
Onchocerca volvulus | 0.011 | 0.0592 | 1 | |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.005 | 0.024 | 0.0426 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.011 | 0.0592 | 0.1339 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0334 | 0.564 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0049 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0394 | 0.6624 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0049 | 0.0126 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0049 | 0.083 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0671 | 0.3887 | 1 |
Leishmania major | hypothetical protein, conserved | 0.011 | 0.0592 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0016 | 0.0264 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0056 | 0.0937 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0394 | 1 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0334 | 0.5246 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.021 | 0.054 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0049 | 0.0049 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0056 | 0.0937 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0592 | 0.1339 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0006 | 0.0015 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0049 | 0.0049 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0049 | 0.083 |
Mycobacterium ulcerans | lipase LipD | 0.011 | 0.0592 | 0.1622 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0056 | 0.0117 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.