Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.2673 | 0.3151 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.3431 | 0.3638 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.1618 | 0.4155 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.2673 | 0.2673 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0007 | 0.0329 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.2673 | 0.3348 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.2673 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.1618 | 0.4155 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.2673 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.8854 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0819 | 0.07 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.3431 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.2673 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0839 | 0.0453 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.1618 | 0.4155 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.2673 | 0.7555 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.2673 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.2673 | 0.3348 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.3431 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.2673 | 0.7555 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.2673 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.2673 | 0.3151 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.7328 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7328 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.2673 | 0.3151 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7328 | 0.7328 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.2673 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.2673 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.2673 | 0.3151 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4619 | 0.4619 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.4331 | 0.5718 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.2673 | 0.3151 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7328 | 0.7328 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.1139 | 0.0894 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.3431 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.3431 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.2673 | 0.7555 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0839 | 0.0728 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.1139 | 0.0894 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.2673 | 0.3348 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.2673 | 0.7555 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0839 | 0.0453 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.3431 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.2673 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4619 | 0.6015 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4331 | 0.4331 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7328 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.7328 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.1618 | 0.4155 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.2673 | 0.3348 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3431 | 0.4432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.3431 | 1 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.1618 | 0.4155 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7328 | 0.7328 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.3431 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4619 | 0.4619 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3431 | 0.4432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7328 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4619 | 0.6015 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1958 | 0.2327 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7328 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0531 | 0.0531 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.2673 | 0.7555 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.2673 | 0.2673 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.2673 | 0.2673 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.4331 | 0.5718 |
Onchocerca volvulus | 0.0031 | 0.4331 | 0.5 | |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.2673 | 0.3151 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.1139 | 0.1139 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.