Detailed information for compound 1255843

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 140.14 | Formula: C6H8N2O2
  • H donors: 1 H acceptors: 2 LogP: -0.87 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCc1ccc(=O)n(n1)C
  • InChi: 1S/C6H8N2O2/c1-8-6(10)3-2-5(4-9)7-8/h2-3,9H,4H2,1H3
  • InChiKey: KTRANNGGLRRVFL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0016 0.0044
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0016 0.0016
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0184 0.1028
Schistosoma mansoni single-minded 0.006 0.0645 0.1299
Echinococcus granulosus protein C ets 2 0.001 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0026 0.022 0.0443
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0115 0.1344 0.8878
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.014 0.1658 0.4512
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0337 0.0847
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0016 0.0032
Leishmania major DNA damage repair protein, putative 0.0035 0.0337 0.0847
Loa Loa (eye worm) hypothetical protein 0.0114 0.1324 0.3638
Schistosoma mansoni ap endonuclease 0.0115 0.1344 0.2707
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2063
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0203 0.0475
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0001 0.0003
Giardia lamblia Inositol 5-phosphatase 4 0.0023 0.0184 0.111
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0023 0.0184 0.058
Leishmania major hypothetical protein, conserved 0.0023 0.0184 0.0422
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0016 0.0044
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Onchocerca volvulus 0.0023 0.0184 0.0464
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0337 0.0337
Echinococcus multilocularis expressed conserved protein 0.0091 0.1038 0.1038
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.1112 0.1112
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0087 0.0152
Schistosoma mansoni hypothetical protein 0.001 0.0021 0.0042
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0184 0.0422
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0337 0.0679
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.3636 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0349 0.121
Schistosoma mansoni jumonji domain containing protein 0.0058 0.062 0.1249
Loa Loa (eye worm) hypothetical protein 0.0147 0.1743 0.4791
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0085 0.0172
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0016 0.0032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0086 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.1212 0.3273
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.022 0.0716
Schistosoma mansoni DNA polymerase eta 0.0139 0.1646 0.3316
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0016 0.0016
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0021 0.0021
Giardia lamblia hypothetical protein 0.0026 0.022 0.1325
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0021 0.0058
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0026 0.022 0.1456
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0203 0.1347
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1663 0.4526
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0115 0.1344 0.3639
Trypanosoma brucei RNA editing exonuclease 2 0.0023 0.0184 0.0422
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0021 0.0058
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0349 0.088
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0087 0.0208
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0023 0.0184 0.0371
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0016 0.0044
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2063
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1658 0.4512
Loa Loa (eye worm) hypothetical protein 0.0061 0.0659 0.181
Loa Loa (eye worm) hypothetical protein 0.0016 0.0087 0.0238
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0509 0.1399
Plasmodium falciparum exonuclease I, putative 0.0026 0.022 0.1456
Echinococcus multilocularis neutral sphingomyelinase 0.0023 0.0184 0.0184
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0021 0.0058
Brugia malayi Fli-1 protein 0.0216 0.2617 0.7193
Schistosoma mansoni ets-related 0.001 0.0021 0.0042
Schistosoma mansoni hypothetical protein 0.004 0.0396 0.0798
Schistosoma mansoni hypothetical protein 0.004 0.0396 0.0798
Trypanosoma brucei unspecified product 0.0079 0.0883 0.2362
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0021 0.0042
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0023 0.0184 0.058
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0115 0.1344 0.7073
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0058
Echinococcus multilocularis traf and tnf receptor associated protein 0.0023 0.0184 0.0184
Schistosoma mansoni elf1 0.001 0.0021 0.0042
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0184 0.1219
Plasmodium falciparum DNA repair protein RAD2, putative 0.0026 0.022 0.1456
Mycobacterium leprae Possible regulatory protein 0.0016 0.0087 0.5
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0123 0.0817
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1663 0.4526
Loa Loa (eye worm) hypothetical protein 0.0017 0.0102 0.028
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0028 0.0076
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0086 0.0237
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0085 0.0147
Echinococcus multilocularis cpg binding protein 0.0032 0.0295 0.0295
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0337 0.0679
Brugia malayi exodeoxyribonuclease III family protein 0.0115 0.1344 0.3692
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0128 0.1509 0.4099
Echinococcus granulosus muscleblind protein 0.0147 0.1743 0.3512
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0337 0.0847
Plasmodium falciparum DNase I-like protein, putative 0.0023 0.0184 0.1219
Echinococcus multilocularis muscleblind protein 0.0147 0.1743 0.1743
Entamoeba histolytica exonuclease, putative 0.0026 0.022 0.127
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0026 0.022 0.052
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0085 0.0147
Echinococcus granulosus traf and tnf receptor associated protein 0.0023 0.0184 0.0371
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0087 0.0152
Schistosoma mansoni flap endonuclease-1 0.0116 0.1354 0.2728
Onchocerca volvulus 0.0297 0.3639 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0016 0.0016
Brugia malayi PAS domain containing protein 0.006 0.0645 0.1772
Leishmania major DNA polymerase eta, putative 0.006 0.0653 0.1724
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0023 0.0184 0.0422
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0789 0.2168
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0415 0.146
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0023 0.0184 0.0371
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0155 0.0155
Schistosoma mansoni hypothetical protein 0.0035 0.0337 0.0679
Echinococcus granulosus dna polymerase kappa 0.0219 0.2653 0.5346
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0174
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0184 0.0422
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0349 0.0704
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0646 0.1302
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.022 0.0716
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0026 0.0219 0.0745
Leishmania major pantothenate kinase subunit, putative 0.0023 0.0184 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0155 0.0427
Echinococcus granulosus expressed conserved protein 0.0091 0.1038 0.2091
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0087 0.0208
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0203 0.1347
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0016 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0016 0.0044
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0115 0.1344 0.3639
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0016 0.0032
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0184 0.1028
Mycobacterium ulcerans hypothetical protein 0.0156 0.1864 0.659
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0087 0.0208
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0023 0.0184 0.1028
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0087 0.0208
Echinococcus multilocularis deoxyribonuclease 1 2 0.0023 0.0184 0.0184
Brugia malayi nuclear receptor NHR-88 0.001 0.0016 0.0044
Brugia malayi hypothetical protein 0.0035 0.0337 0.0926
Brugia malayi ImpB/MucB/SamB family protein 0.0139 0.1646 0.4524
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0023 0.0184 0.058
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0417 0.1069
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0016 0.0016
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0349 0.2148
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0174
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0789 0.0789
Echinococcus granulosus neutral sphingomyelinase 0.0023 0.0184 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0337 0.0847
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0023 0.0184 0.0506
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.0574
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0016 0.0032
Onchocerca volvulus Putative neutral sphingomyelinase 0.0023 0.0184 0.0464
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0087 0.0208
Echinococcus multilocularis ets variant gene 4 0.001 0.0021 0.0021
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0219 0.2653 1
Schistosoma mansoni hypothetical protein 0.004 0.0396 0.0798
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0016 0.0044
Echinococcus granulosus phd:f box containing protein 0.0015 0.0085 0.0172
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.1112 0.3055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0016 0.0044
Trypanosoma brucei DNA repair protein RAD2, putative 0.0026 0.022 0.052
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0337 0.0847
Plasmodium vivax JmjC domain containing protein 0.0015 0.0085 0.0146
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0087 0.0208
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0115 0.1344 0.2707
Leishmania major protein kinase, putative 0.0016 0.0087 0.0152
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.1112 0.7308
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Echinococcus multilocularis protein C ets 2 0.001 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0016 0.0044
Echinococcus multilocularis exonuclease 1 0.0026 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0184 0.0506
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.0093 0.0188
Echinococcus multilocularis protein patched 0.0042 0.0415 0.0415
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0023 0.0184 0.0371
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0174
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0087 0.0574
Toxoplasma gondii hypothetical protein 0.0048 0.0495 0.3279
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0086 0.0237
Loa Loa (eye worm) hypothetical protein 0.0023 0.0184 0.0506
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0016 0.0087 0.5
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.022 0.0716
Leishmania major hypothetical protein, conserved 0.0025 0.0203 0.0475
Trypanosoma cruzi DNA polymerase eta, putative 0.0139 0.1646 0.4478
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0234
Schistosoma mansoni hypothetical protein 0.0011 0.0031 0.0062
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0128 0.1509 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0026 0.022 0.1456
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Trypanosoma brucei DNA polymerase IV, putative 0.0193 0.2325 0.6362
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0113 0.1317 0.362
Loa Loa (eye worm) fli-1 protein 0.0216 0.2617 0.7193
Treponema pallidum exodeoxyribonuclease (exoA) 0.0115 0.1344 1
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0337 0.0847
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Echinococcus multilocularis dna polymerase kappa 0.0219 0.2653 0.2653
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.1131 0.2278
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0114 0.133 0.268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0016 0.0044
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0026 0.022 0.052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0533 0.1464
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0415 0.0415
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0417 0.1069
Echinococcus multilocularis transfer RNA-Lys 0.0044 0.0449 0.0449
Echinococcus multilocularis aryl hydrocarbon receptor 0.0129 0.152 0.152
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Loa Loa (eye worm) hypothetical protein 0.0097 0.1112 0.3055
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0087 0.0152
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0087 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0349 0.121
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0021 0.0021
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0016 0.0032
Leishmania major DNA polymerase kappa, putative 0.0035 0.0337 0.0847
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0134 0.0134
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0337 0.0847
Brugia malayi Ets-domain containing protein 0.0071 0.0789 0.2168
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0184 0.0506
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0016 0.0032
Leishmania major protein kinase, putative 0.0016 0.0087 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.022 0.052
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0087
Schistosoma mansoni ap endonuclease 0.0115 0.1344 0.2707
Brugia malayi MH2 domain containing protein 0.0117 0.1371 0.3769
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0184 0.0829
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0669 0.1347
Echinococcus granulosus flap endonuclease GEN 1 0.0026 0.022 0.0443
Brugia malayi Ets-domain containing protein 0.0071 0.0789 0.2168
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0085 0.0172
Mycobacterium ulcerans putative regulatory protein 0.0044 0.0449 0.0481
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0087 0.0208
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.0151
Echinococcus multilocularis protein dispatched 1 0.0047 0.0489 0.0489
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0566 0.3747
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0087 0.0152
Schistosoma mansoni neutral sphingomyelinase 0.0023 0.0184 0.0371
Entamoeba histolytica DNA-repair protein, putative 0.0026 0.022 0.127
Trypanosoma brucei unspecified product 0.0193 0.2325 0.6362
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0789 0.1589
Onchocerca volvulus 0.0028 0.0247 0.0637
Loa Loa (eye worm) hypothetical protein 0.0147 0.1743 0.4791
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0023 0.0184 0.0184
Brugia malayi isocitrate dehydrogenase 0.0016 0.0087 0.0238
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0026 0.022 0.1456
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0085 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0155 0.047
Leishmania major RNA-editing complex protein MP100, putative 0.0023 0.0184 0.0422
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0086 0.0174
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0115 0.1344 0.3692
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0234
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0021 0.0042
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.3636 1
Brugia malayi XPG N-terminal domain containing protein 0.0012 0.0046 0.0127
Schistosoma mansoni cript-related 0.0023 0.0184 0.0371
Schistosoma mansoni hypothetical protein 0.001 0.0021 0.0042
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0026 0.022 0.022
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.0151
Brugia malayi polk-prov protein 0.014 0.1661 0.4564
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0023 0.0184 0.058
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Plasmodium falciparum endonuclease, putative 0.0014 0.0064 0.0426
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.022 0.0604
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0023 0.0184 0.0422
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0068 0.0448
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.007 0.0038
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0533 0.1389
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Brugia malayi nuclear hormone receptor 0.001 0.0016 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1661 0.4519
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Schistosoma mansoni thyroid hormone receptor 0.001 0.0016 0.0032
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0023 0.0184 0.0422
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0085 0.0172
Schistosoma mansoni cpg binding protein 0.0028 0.0247 0.0497
Loa Loa (eye worm) hypothetical protein 0.0297 0.3639 1
Leishmania major DNA polymerase eta, putative 0.0139 0.1646 0.4478
Loa Loa (eye worm) RecQ helicase 0.0021 0.0155 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0234
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0184 0.058
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0031 0.0062
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.014 0.1658 0.8845
Echinococcus multilocularis GPCR, family 2 0.0015 0.0086 0.0086
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0016 0.0044
Echinococcus granulosus GPCR family 2 0.0015 0.0086 0.0174
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0087 0.0152
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0415 0.114
Schistosoma mansoni coup transcription factor 0.001 0.0016 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0016 0.0032
Brugia malayi jmjC domain containing protein 0.0062 0.0669 0.1838
Schistosoma mansoni hypothetical protein 0.0033 0.0313 0.0631
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0021 0.0058
Leishmania major hypothetical protein, conserved 0.0015 0.0085 0.0147
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0184 0.0422
Loa Loa (eye worm) hypothetical protein 0.0049 0.0509 0.1399
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0337 0.2236
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0016 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.1864 1
Brugia malayi CHE-14 protein 0.0042 0.0415 0.114
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0174
Loa Loa (eye worm) hypothetical protein 0.0015 0.0086 0.0237
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0023 0.0184 0.1028
Leishmania major endonuclease/exonuclease protein-like protein 0.0023 0.0184 0.0422
Onchocerca volvulus 0.0023 0.0184 0.0464
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0016 0.0044
Entamoeba histolytica deoxycytidyl transferase, putative 0.0114 0.133 0.8786
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0085 0.0172
Mycobacterium tuberculosis Probable exported protein 0.0023 0.0184 0.0548
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Schistosoma mansoni aryl hydrocarbon receptor 0.0173 0.2078 0.4186
Giardia lamblia hypothetical protein 0.0023 0.0184 0.111
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0234
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0234
Loa Loa (eye worm) hypothetical protein 0.0129 0.1513 0.4158
Loa Loa (eye worm) hypothetical protein 0.012 0.141 0.3875
Brugia malayi hypothetical protein 0.0025 0.0203 0.0559
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0087 0.0238
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0184 0.0829
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0349 0.0704
Brugia malayi ImpB/MucB/SamB family protein 0.0114 0.133 0.3655
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0669 0.1347
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0085 0.0147
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0349 0.096
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0139 0.1646 0.4524
Schistosoma mansoni cpg binding protein 0.0032 0.0295 0.0595
Schistosoma mansoni synaptojanin 0.0023 0.0184 0.0371
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0087 0.0208
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0023 0.0184 0.0422
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0087 0.0208
Brugia malayi transcription factor E74 isoform 0.001 0.0021 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0219 0.2653 0.7273
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0349 0.096
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.0093 0.0093
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.000000000049752 0.00000000032961
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0669 0.1838
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0001 0.0002
Trichomonas vaginalis DNA polymerase eta, putative 0.0219 0.2653 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0509 0.1399
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0016 0.0044
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0184 0.058
Brugia malayi Muscleblind-like protein 0.0147 0.1743 0.4791
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.0653 0.4329
Echinococcus granulosus cpg binding protein 0.0032 0.0295 0.0595
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0021 0.0021
Echinococcus granulosus aryl hydrocarbon receptor 0.0129 0.152 0.3062
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0085 0.0172
Toxoplasma gondii exonuclease III APE 0.0115 0.1344 0.8902
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0134 0.027
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0016 0.0032
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2063
Leishmania major hypothetical protein, conserved 0.0023 0.0184 0.0422
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0023 0.0184 0.0422
Loa Loa (eye worm) hypothetical protein 0.012 0.141 0.3875
Brugia malayi CXXC zinc finger family protein 0.0028 0.0247 0.0679
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0021 0.0021
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0184 0.0422
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Loa Loa (eye worm) XPG I-region family protein 0.0026 0.022 0.0604
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0016 0.0044
Entamoeba histolytica exonuclease, putative 0.0026 0.022 0.127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0016 0.0044
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0023 0.0184 0.0422
Schistosoma mansoni hypothetical protein 0.0012 0.0046 0.0093
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0021 0.0058
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0337 0.2236
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0114 0.133 0.133
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0016 0.0032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0349 0.088
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0115 0.1344 0.8902
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.022 0.0604
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0087 0.0087
Brugia malayi hypothetical protein 0.012 0.141 0.3875
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0115 0.1344 0.4344
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.1212 0.3273
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0234
Giardia lamblia Flap structure-specific endonuclease 0.0128 0.1509 0.9101
Plasmodium vivax exonuclease I, putative 0.0026 0.022 0.1076
Brugia malayi hypothetical protein 0.0016 0.0087 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1661 0.4519
Brugia malayi bHLH-PAS transcription factor 0.0044 0.0449 0.1234
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0184 0.0422
Brugia malayi Ets-domain containing protein 0.001 0.0021 0.0058
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.1636 0.1636
Loa Loa (eye worm) hypothetical protein 0.0023 0.0184 0.0506
Schistosoma mansoni thyroid hormone receptor 0.001 0.0016 0.0032
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.3636 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0349 0.0704
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.0151
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0415 0.114
Giardia lamblia Exonuclease 1 0.0026 0.022 0.1325
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0087
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0203 0.0475
Plasmodium vivax exodeoxyribonuclease III, putative 0.0023 0.0184 0.0829
Brugia malayi ecdysteroid receptor 0.001 0.0016 0.0044
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0184 0.0371
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0086 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0016 0.0044
Schistosoma mansoni ets 0.001 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0184 0.0506
Trichomonas vaginalis Phospholipase C precursor, putative 0.0023 0.0184 0.058
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0337 0.068
Schistosoma mansoni hypothetical protein 0.0012 0.0046 0.0093
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0023 0.0184 0.0422
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0349 0.088
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0114 0.133 0.3655
Entamoeba histolytica hypothetical protein 0.0012 0.0046 0.0096
Schistosoma mansoni synaptojanin 0.0023 0.0184 0.0371
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0203 0.1347
Onchocerca volvulus 0.0129 0.1513 0.4132
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.01 0.0201
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0087 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0087 0.0208
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Leishmania major DNA repair protein RAD2, putative 0.0012 0.0046 0.0039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0023 0.0184 0.0371
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0016 0.0032
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1371 0.3769
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0349 0.121
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0234
Echinococcus granulosus dnaJ subfamily B 0.0402 0.4964 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0016 0.0044
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1663 0.4526
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0023 0.0184 0.1219
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.1636 0.3296
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0184 0.0829
Echinococcus multilocularis flap endonuclease 1 0.0128 0.1509 0.1509
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Trypanosoma brucei DNA polymerase IV, putative 0.0219 0.2653 0.7273
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0203 0.0475
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0114 0.133 0.6997
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0115 0.1344 0.1344
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0021 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0087
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0087 0.0175
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0023 0.0184 0.0184
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0016 0.0032
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0313 0.0861
Schistosoma mansoni gabp alpha 0.0071 0.0789 0.1589
Loa Loa (eye worm) hypothetical protein 0.0025 0.0203 0.0559
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0247 0.0679
Echinococcus granulosus synaptojanin 1 0.0023 0.0184 0.0371
Schistosoma mansoni patched 1 0.0042 0.0415 0.0836
Echinococcus multilocularis flap endonuclease GEN 1 0.0026 0.022 0.022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0016 0.0016
Schistosoma mansoni cpg binding protein 0.0032 0.0295 0.0595
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0023 0.0184 0.0422
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0184 0.0506
Loa Loa (eye worm) hypothetical protein 0.0033 0.0313 0.0861
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0016 0.0044
Schistosoma mansoni terminal deoxycytidyl transferase 0.0114 0.133 0.268
Schistosoma mansoni hypothetical protein 0.0402 0.4964 1
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0349 0.0704
Schistosoma mansoni carbon catabolite repressor protein 0.0023 0.0184 0.0371
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0415 0.0836
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0085 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0086 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Trypanosoma brucei exonuclease, putative 0.0026 0.022 0.052
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0337 0.0847
Trichomonas vaginalis exonuclease%2C+putative 0.0026 0.022 0.0716
Schistosoma mansoni ets-related 0.0216 0.2617 0.5273
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0087 0.0151
Echinococcus granulosus single minded 2 0.0044 0.0449 0.0904
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0115 0.1344 0.3639
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0016 0.0044
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0087 0.0087
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0115 0.1344 0.8102
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0021 0.0042
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0023 0.0184 0.1219
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1219
Loa Loa (eye worm) flap endonuclease-1 0.0128 0.1509 0.4148
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.1112 0.224
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0058
Brugia malayi steroid hormone receptor 0.001 0.0016 0.0044
Giardia lamblia DNA damage repair protein 0.0035 0.0337 0.2035
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0155 0.047
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.1212 0.3273
Echinococcus multilocularis dna polymerase eta 0.0139 0.1646 0.1646
Brugia malayi XPG I-region family protein 0.0026 0.022 0.0604
Echinococcus granulosus flap endonuclease 1 0.0128 0.1509 0.3041
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0128 0.1509 0.4099
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0417 0.1069
Plasmodium vivax DNA repair protein RAD2, putative 0.0026 0.022 0.1076
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0011 0.0024 0.0161
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0023 0.0184 0.058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0234
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0509 0.1399
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0085 0.0565
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0184 0.0422
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0085 0.0565
Onchocerca volvulus 0.0045 0.0455 0.1213
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.4964 0.4964
Echinococcus granulosus FTZ F1 alpha 0.001 0.0016 0.0032
Echinococcus multilocularis synaptojanin 1 0.0023 0.0184 0.0184
Trichomonas vaginalis ap endonuclease, putative 0.0115 0.1344 0.5003
Brugia malayi jmjC domain containing protein 0.0058 0.062 0.1704
Entamoeba histolytica Flap nuclease, putative 0.0128 0.1509 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0087 0.0152
Mycobacterium ulcerans DNA polymerase IV 0.0219 0.2653 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0085 0.0172
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.062 0.1249
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0085 0.0085
Plasmodium falciparum flap endonuclease 1 0.0128 0.1509 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.3636 1
Schistosoma mansoni hypothetical protein 0.004 0.0396 0.0798
Giardia lamblia DINP protein human, muc B family 0.014 0.1658 1
Mycobacterium ulcerans DNA polymerase IV 0.0219 0.2653 1
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0415 0.0836
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0016 0.0093 0.0256
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0115 0.1344 0.3639
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0016 0.0016
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.0574
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.062 0.062
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0016 0.0016
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0184 0.0422
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0128 0.1509 0.4099
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Echinococcus granulosus dna polymerase eta 0.0139 0.1646 0.3316
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0085 0.0172
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0026 0.022 0.0443
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0203 0.0963
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0085 0.0172
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0115 0.1344 0.8853
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0085 0.0565
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0337 0.1891
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0184 0.058
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0021 0.0042
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0349 0.088
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0061 0.0666 0.4411
Onchocerca volvulus Huntingtin homolog 0.012 0.141 0.3848
Trichomonas vaginalis ap endonuclease, putative 0.0115 0.1344 0.5003
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.022 0.0716
Echinococcus multilocularis muscleblind protein 1 0.0147 0.1743 0.1743
Brugia malayi CCR4 0.0023 0.0184 0.0506
Trypanosoma brucei DNA polymerase eta, putative 0.0139 0.1646 0.4478
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.022 0.052
Brugia malayi Flap endonuclease-1 0.0128 0.1509 0.4148
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0337 0.0847
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2063
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0021 0.0042
Onchocerca volvulus Huntingtin homolog 0.012 0.141 0.3848
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0184 0.1028
Echinococcus granulosus bloom syndrome protein 0.0021 0.0155 0.0313
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0023 0.0184 0.0422
Schistosoma mansoni nocturnin 0.0023 0.0184 0.0371
Leishmania major hypothetical protein, conserved 0.0023 0.0184 0.0422
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0184 0.0506
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0184 0.0506
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.0113 0.1317 0.362
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0234
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0087 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0016 0.0044
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0026 0.022 0.1456
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0184 0.0184
Echinococcus granulosus exonuclease 1 0.0026 0.022 0.0443
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0114 0.133 0.268
Leishmania major DNA polymerase kappa, putative 0.014 0.1658 0.4512
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0349 0.0704
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0016 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0337 0.0847
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0016 0.0044
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0653 0.1724
Trichomonas vaginalis flap endonuclease-1, putative 0.0128 0.1509 0.5636
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0016 0.0032
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0023 0.0184 0.1028
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0016 0.0044
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0417 0.1069
Brugia malayi XPG N-terminal domain containing protein 0.0012 0.0046 0.0127
Plasmodium vivax flap endonuclease 1, putative 0.0128 0.1509 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0016 0.0032
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0184 0.1219
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0349 0.0349
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0087 0.0208
Brugia malayi hypothetical protein 0.0297 0.3639 1
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0026 0.022 0.0443
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.014 0.1661 0.4564
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0669 0.1347
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.062 0.062
Leishmania major hypothetical protein, conserved 0.0026 0.022 0.052
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0349 0.2107
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0115 0.1344 0.5
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0087 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2653 0.7273
Schistosoma mansoni nuclear hormone receptor 0.001 0.0016 0.0032
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0016 0.0032
Trypanosoma brucei unspecified product 0.0079 0.0883 0.2362
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0184 0.0506
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0085 0.0085
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1371 0.3769
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0184 0.0506
Brugia malayi hypothetical protein 0.0016 0.0093 0.0254
Schistosoma mansoni exonuclease 0.0026 0.022 0.0443
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0349 0.0349

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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