Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0015 | 0.1472 | 0.4426 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0468 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0015 | 0.1472 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0015 | 0.1472 | 0.3513 |
Echinococcus granulosus | lamin dm0 | 0.0024 | 0.3325 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0015 | 0.1472 | 0.4426 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0015 | 0.1472 | 0.4426 |
Echinococcus granulosus | intermediate filament protein | 0.0024 | 0.3325 | 1 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.001 | 0.0468 | 0.1408 |
Brugia malayi | intermediate filament protein | 0.0024 | 0.3325 | 1 |
Plasmodium vivax | vivapain-2 | 0.0015 | 0.1472 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0044 | 0.7525 | 0.7525 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.3325 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0468 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Schistosoma mansoni | lamin | 0.0024 | 0.3325 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0015 | 0.1472 | 0.4426 |
Onchocerca volvulus | Cathepsin F homolog | 0.0015 | 0.1472 | 0.3513 |
Entamoeba histolytica | cysteine protease, putative | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0024 | 0.3325 | 1 |
Onchocerca volvulus | 0.0024 | 0.3325 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0056 | 1 | 1 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0015 | 0.1472 | 0.3513 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Onchocerca volvulus | Cathepsin L homolog | 0.0015 | 0.1472 | 0.3513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.001 | 0.0468 | 0.1408 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0013 | 0.1055 | 0.3174 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0024 | 0.3325 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Onchocerca volvulus | 0.0024 | 0.3325 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0015 | 0.1472 | 0.4426 |
Toxoplasma gondii | cathepsin CPL | 0.0015 | 0.1472 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0015 | 0.1472 | 0.3513 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0056 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0024 | 0.3325 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0015 | 0.1472 | 0.4426 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.001 | 0.0468 | 0.1408 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0015 | 0.1472 | 1 |
Plasmodium vivax | vivapain-2 | 0.0015 | 0.1472 | 1 |
Leishmania major | cathepsin L-like protease | 0.0056 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.001 | 0.0468 | 0.1408 |
Echinococcus multilocularis | lamin dm0 | 0.0024 | 0.3325 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.3235 | 0.9687 |
Loa Loa (eye worm) | ctsf protein | 0.0015 | 0.1472 | 0.3513 |
Schistosoma mansoni | intermediate filament proteins | 0.0024 | 0.3325 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0051 | 0.8997 | 0.8997 |
Onchocerca volvulus | Cathepsin L homolog | 0.0015 | 0.1472 | 0.3513 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0796 | 0.1146 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0015 | 0.1472 | 0.4426 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0011 | 0.0796 | 0.2393 |
Echinococcus granulosus | cathepsin l1 | 0.001 | 0.0468 | 0.1408 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0011 | 0.0796 | 0.2393 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0015 | 0.1472 | 0.1472 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Onchocerca volvulus | 0.0015 | 0.1472 | 0.3513 | |
Echinococcus multilocularis | lamin | 0.0024 | 0.3325 | 1 |
Schistosoma mansoni | lamin | 0.0024 | 0.3325 | 1 |
Leishmania major | cathepsin L-like protease | 0.0056 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.001 | 0.0468 | 0.1408 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0015 | 0.1472 | 0.3513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0706 | 0.0833 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0015 | 0.1472 | 0.4426 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0015 | 0.1472 | 0.4426 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0024 | 0.3325 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0706 | 0.0833 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0015 | 0.1472 | 0.4426 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0015 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0056 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0015 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0015 | 0.1472 | 0.4426 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.1472 | 0.3513 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0013 | 0.1055 | 0.2055 |
Echinococcus multilocularis | musashi | 0.0024 | 0.3325 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0015 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0015 | 0.1472 | 0.4426 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0468 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0015 | 0.1472 | 0.4426 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.