Detailed information for compound 1257739

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 852.053 | Formula: C39H65N9O10S
  • H donors: 8 H acceptors: 10 LogP: 0.64 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 3
  • SMILES: CSCC[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]2N(C(=O)[C@@H](NC(=O)[C@H]3N(C(=O)[C@@H](NC1=O)CC(C)C)CCC3)[C@H](CC)C)CCC2)[C@H](O)C
  • InChi: 1S/C39H65N9O10S/c1-8-21(4)30-39(58)48-17-10-11-27(48)35(54)43-24(13-14-29(40)50)34(53)46-31(23(6)49)37(56)41-22(5)32(51)42-25(15-18-59-7)33(52)44-26(19-20(2)3)38(57)47-16-9-12-28(47)36(55)45-30/h20-28,30-31,49H,8-19H2,1-7H3,(H2,40,50)(H,41,56)(H,42,51)(H,43,54)(H,44,52)(H,45,55)(H,46,53)/t21-,22-,23+,24-,25-,26-,27-,28-,30-,31-/m0/s1
  • InChiKey: IXUJFHPXFZVQOX-YAROKCEMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Schistosoma mansoni hypothetical protein 0.0171 0.111 0.111
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0858 0.2165
Schistosoma mansoni hypothetical protein 0.0142 0.0899 0.0899
Trypanosoma cruzi thymidine kinase, putative 0.0504 0.3592 1
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0103 0.1145
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0103 0.0225
Brugia malayi beta-lactamase family protein 0.0036 0.0103 0.045
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0167 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Toxoplasma gondii ribonuclease HI protein 0.0043 0.0158 0.154
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.1363 1 1
Brugia malayi beta-lactamase family protein 0.0036 0.0103 0.045
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0023 0.0253
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0103 0.0103
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.011 0.0243
Echinococcus multilocularis ribonuclease H1 0.0043 0.0158 0.0158
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0208 0.0518
Giardia lamblia Hypothetical protein 0.0137 0.0858 0.0779
Entamoeba histolytica glycogen phosphorylase, putative 0.0328 0.2285 0.6249
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0167 0.0167
Onchocerca volvulus 0.0054 0.024 0.1049
Brugia malayi beta-lactamase 0.0036 0.0103 0.045
Entamoeba histolytica Thymidylate kinase, putative 0.0142 0.0899 0.2267
Echinococcus granulosus glycogen phosphorylase 0.0328 0.2285 0.2285
Brugia malayi RNase H family protein 0.0043 0.0158 0.069
Trypanosoma brucei ingi protein (ORF1) 0.005 0.0208 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0858 0.2165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0131 0.0816 0.0816
Onchocerca volvulus Putative thymidylate kinase 0.0142 0.0899 0.3933
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.011 0.0019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0103 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Echinococcus multilocularis cytidine deaminase 0.0054 0.024 0.024
Echinococcus granulosus solute carrier family 28 0.0346 0.242 0.242
Trypanosoma cruzi ribonuclease H1, putative 0.0043 0.0158 0.0378
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0197 0.0861
Schistosoma mansoni thymidylate kinase 0.0142 0.0899 0.0899
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.0142 0.0899 0.5604
Echinococcus granulosus Na+ dependent nucleoside transporter 0.0346 0.242 0.242
Leishmania major hypothetical protein, conserved 0.0036 0.0103 0.0225
Trypanosoma cruzi thymidylate kinase, putative 0.0142 0.0899 0.2455
Trichomonas vaginalis ribonuclease H1, putative 0.0043 0.0158 0.0157
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0103 0.0151
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0103 0.0151
Trichomonas vaginalis thymidine kinase, putative 0.0504 0.3592 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0197 0.0861
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0056 0.0253 0.0646
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.011 0.0243
Trichomonas vaginalis thymidylate kinase, putative 0.0142 0.0899 0.2281
Trypanosoma cruzi thymidylate kinase, putative 0.0142 0.0899 0.2455
Wolbachia endosymbiont of Brugia malayi thymidylate kinase 0.0142 0.0899 1
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0783 0.0783
Giardia lamblia Hypothetical protein 0.0137 0.0858 0.0779
Echinococcus granulosus glycogen phosphorylase 0.0328 0.2285 0.2285
Echinococcus multilocularis glycogen phosphorylase 0.0328 0.2285 0.2285
Echinococcus multilocularis glycogen phosphorylase 0.0328 0.2285 0.2285
Schistosoma mansoni phosphoglucomutase 0.0043 0.0158 0.0158
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.0226 0.1521 0.1521
Trichomonas vaginalis cytidine deaminase, putative 0.0054 0.024 0.0392
Schistosoma mansoni inositol monophosphatase 0.0037 0.011 0.011
Giardia lamblia Thymidine kinase 0.0504 0.3592 0.3819
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0131 0.0816 0.0816
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.011 0.0991
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.011 0.0243
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0103 0.0151
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0103 0.0151
Trypanosoma brucei cytidine deaminase 0.0054 0.024 0.0608
Mycobacterium leprae Probable lipase LipE 0.0036 0.0103 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0167 0.0167
Echinococcus granulosus thymidylate kinase 0.0142 0.0899 0.0899
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0103 0.0225
Trypanosoma brucei ribonuclease H1 0.0043 0.0158 0.0378
Brugia malayi Deoxynucleoside kinase family protein 0.0137 0.0858 0.3754
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0197 0.0861
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0103 0.0269
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.0346 0.242 0.242
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.0151
Giardia lamblia Cytidine deaminase 0.0054 0.024 0.0091
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0137 0.0858 0.215
Brugia malayi cytidine deaminase, identical 0.0054 0.024 0.1049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0103 0.0151
Trypanosoma cruzi cytidine deaminase-like protein, putative 0.0054 0.024 0.0608
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0137 0.0858 0.0858
Schistosoma mansoni phosphoglucomutase 0.0043 0.0158 0.0158
Schistosoma mansoni glycogen phosphorylase 0.0328 0.2285 0.2285
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0137 0.0858 0.215
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Brugia malayi Inositol-1 0.0037 0.011 0.0479
Echinococcus multilocularis transfer RNA-Ile 0.1363 1 1
Entamoeba histolytica glycogen phosphorylase, putative 0.0142 0.0895 0.2256
Brugia malayi hypothetical protein 0.0025 0.0023 0.0099
Toxoplasma gondii thymidylate kinase 0.0142 0.0899 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Echinococcus multilocularis thymidine kinase 0.1363 1 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.011 0.011
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0137 0.0858 0.215
Loa Loa (eye worm) beta-lactamase 0.0036 0.0103 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Mycobacterium ulcerans cytidine deaminase 0.0054 0.024 0.1718
Schistosoma mansoni thymidine kinase 0.1363 1 1
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0043 0.0158 0.061
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Schistosoma mansoni lipoxygenase 0.0131 0.0816 0.0816
Echinococcus multilocularis solute carrier family 28 0.0346 0.242 0.242
Onchocerca volvulus 0.0036 0.0103 0.045
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.011 0.0019
Leishmania major cathepsin L-like protease 0.0056 0.0255 0.065
Mycobacterium tuberculosis Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) 0.0054 0.024 0.1088
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0083 0.0362
Entamoeba histolytica glycogen phosphorylase, putative 0.0142 0.0895 0.2256
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.011 0.0243
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Leishmania major cathepsin L-like protease 0.0056 0.0255 0.065
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0861
Schistosoma mansoni glycogen phosphorylase 0.0142 0.0895 0.0895
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.0137 0.0858 0.0858
Entamoeba histolytica glycogen phosphorylase, putative 0.0328 0.2285 0.6249
Trypanosoma brucei thymidine kinase 0.0504 0.3592 1
Trichomonas vaginalis thymidine kinase, putative 0.0504 0.3592 1
Schistosoma mansoni thymidylate kinase 0.0142 0.0899 0.0899
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.0137 0.0858 0.0779
Giardia lamblia CDC8 0.0142 0.0899 0.0824
Brugia malayi RNase H family protein 0.0043 0.0158 0.069
Schistosoma mansoni glycogen phosphorylase 0.0328 0.2285 0.2285
Onchocerca volvulus Ribonuclease H1 homolog 0.0043 0.0158 0.069
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Plasmodium falciparum thymidylate kinase 0.0142 0.0899 1
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0858 0.2165
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0051 0.0218 0.0549
Brugia malayi carbohydrate phosphorylase 0.0328 0.2285 1
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0056 0.0253 0.0646
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0137 0.0858 0.215
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0255 0.065
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.154 1
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0255 0.065
Echinococcus multilocularis thyroid hormone receptor alpha 0.0137 0.0859 0.0859
Entamoeba histolytica glycogenphosphorylase, putative 0.0142 0.0895 0.2256
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0103 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0023 0.0253
Trypanosoma cruzi thymidine kinase, putative 0.0504 0.3592 1
Onchocerca volvulus 0.0054 0.024 0.1049
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0103 0.0103
Loa Loa (eye worm) inositol-1 0.0037 0.011 0.0479
Echinococcus granulosus cytidine deaminase 0.0054 0.024 0.024
Mycobacterium ulcerans thymidylate kinase 0.0142 0.0899 1
Schistosoma mansoni lipoxygenase 0.0092 0.0521 0.0521
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0255 0.065
Trichomonas vaginalis glycogen phosphorylase, putative 0.0328 0.2285 0.6256
Echinococcus granulosus Glycosyl transferase family 35 0.0328 0.2285 0.2285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0167 0.0167
Leishmania major thymidylate kinase-like protein 0.0142 0.0899 0.2455
Echinococcus granulosus ribonuclease H1 0.0043 0.0158 0.0158
Trypanosoma brucei thymidylate kinase, putative 0.0142 0.0899 0.2455
Giardia lamblia Glycogen phosphorylase 0.0328 0.2285 0.2366
Trypanosoma brucei unspecified product 0.005 0.0208 0.0518
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.011 0.011
Toxoplasma gondii ABC1 family protein 0.0036 0.0103 0.0915
Schistosoma mansoni hypothetical protein 0.0052 0.0225 0.0225
Leishmania major thymidine kinase, putative 0.0504 0.3592 1
Trypanosoma cruzi ribonuclease H1, putative 0.0043 0.0158 0.0378
Schistosoma mansoni phosphoglucomutase 0.0043 0.0158 0.0158
Trypanosoma brucei ingi protein (ORF1) 0.005 0.0208 0.0518
Echinococcus multilocularis thymidylate kinase 0.0142 0.0899 0.0899
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.0142 0.0899 1
Echinococcus multilocularis thymidine kinase 0.1363 1 1
Schistosoma mansoni hypothetical protein 0.0033 0.0083 0.0083
Echinococcus granulosus geminin 0.0171 0.111 0.111
Trypanosoma brucei thymidylate kinase, putative 0.0142 0.0899 0.2455
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0167 0.0731
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.011 0.0019
Brugia malayi thymidylate kinase 0.0142 0.0899 0.3933
Loa Loa (eye worm) thymidylate kinase 0.0142 0.0899 0.3933
Trichomonas vaginalis thymidylate kinase, putative 0.0142 0.0899 0.2281
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Trypanosoma cruzi cytidine deaminase-like protein 0.0054 0.024 0.0608
Trichomonas vaginalis thymidine kinase, putative 0.0504 0.3592 1
Mycobacterium leprae PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) 0.0054 0.024 0.1941
Schistosoma mansoni inositol monophosphatase 0.0037 0.011 0.011
Trichomonas vaginalis glycogen phosphorylase, putative 0.0328 0.2285 0.6256
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0167 0.0167
Trypanosoma cruzi cruzipain precursor, putative 0.0056 0.0255 0.065
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Leishmania major cytidine deaminase-like protein 0.0054 0.024 0.0608
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0167 0.0167
Onchocerca volvulus Glycogen phosphorylase homolog 0.0328 0.2285 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Entamoeba histolytica thymidine kinase, putative 0.0504 0.3592 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.011 0.0083
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0099
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0859 0.0859
Leishmania major ribonuclease H1, putative 0.0043 0.0158 0.0378
Treponema pallidum thymidylate kinase (tmk) 0.0142 0.0899 1
Toxoplasma gondii cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein 0.0054 0.024 0.2476
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0858 0.2165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.045
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.0346 0.242 0.242
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Plasmodium vivax thymidylate kinase, putative 0.0142 0.0899 1
Loa Loa (eye worm) glycogen phosphorylase 0.0328 0.2285 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0103 0.045
Leishmania major cathepsin L-like protease 0.0056 0.0255 0.065
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.0137 0.0858 0.0858
Giardia lamblia Deoxynucleoside kinase 0.1249 0.915 1
Trypanosoma brucei RNA helicase, putative 0.0296 0.204 0.5653
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0142 0.0895 0.9954
Echinococcus multilocularis Glycosyl transferase, family 35 0.0328 0.2285 0.2285
Leishmania major hypothetical protein, conserved 0.0056 0.0253 0.0646
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0142 0.0895 0.5579
Trypanosoma cruzi major cysteine proteinase, putative 0.0044 0.0165 0.0399
Onchocerca volvulus 0.0036 0.0103 0.045
Chlamydia trachomatis glycogen phosphorylase 0.0328 0.2285 1
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0858 0.2165
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.005 0.0208 0.0518
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0023 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0103 0.0225
Entamoeba histolytica cytidine deaminase, putative 0.0054 0.024 0.0374
Onchocerca volvulus 0.0036 0.0103 0.045
Echinococcus granulosus thymidine kinase 0.1363 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0103 0.0151
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0103 0.0151
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.0151
Loa Loa (eye worm) deoxynucleoside kinase 0.0137 0.0858 0.3754
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.0151
Echinococcus multilocularis geminin 0.0171 0.111 0.111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Schistosoma mansoni hypothetical protein 0.0296 0.204 0.204
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0167 0.0731
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0362
Brugia malayi RNase H family protein 0.0043 0.0158 0.069
Schistosoma mansoni hypothetical protein 0.0127 0.0783 0.0783
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0255 0.065
Schistosoma mansoni hypothetical protein 0.0171 0.111 0.111
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0783 0.0783
Entamoeba histolytica hypothetical protein 0.0137 0.0858 0.215
Trichomonas vaginalis cytidine deaminase, putative 0.0054 0.024 0.0392

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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