Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.044 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0415 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0035 | 0.0108 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.0379 | 0.1167 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0026 | 0.0089 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.004 | 0.0257 | 0.0257 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0045 | 0.0103 |
Brugia malayi | Pre-SET motif family protein | 0.0211 | 0.2374 | 0.731 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0152 | 0.1648 | 0.1618 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0022 | 0.0035 | 0.0119 |
Schistosoma mansoni | nuclear hormone receptor | 0.012 | 0.1245 | 0.1214 |
Brugia malayi | nuclear receptor RXR | 0.0056 | 0.0463 | 0.1396 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0077 | 0.0723 | 0.3603 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0179 | 0.1986 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0063 | 0.0547 | 0.0513 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0045 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1648 | 0.508 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0035 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.012 | 0.1245 | 0.384 |
Leishmania major | farnesyltransferase beta subunit | 0.0022 | 0.0035 | 0.0119 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0547 | 0.1655 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.012 | 0.1245 | 0.1245 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0379 | 0.1858 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.012 | 0.1245 | 0.3818 |
Schistosoma mansoni | coup transcription factor | 0.012 | 0.1245 | 0.1214 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0415 | 0.1278 |
Leishmania major | geranylgeranyltransferase, putative | 0.0022 | 0.0035 | 0.0119 |
Trypanosoma cruzi | geranylgeranyl transferase type II beta subunit, putative | 0.0022 | 0.0035 | 0.0119 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.0258 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0077 | 0.0723 | 0.0723 |
Onchocerca volvulus | 0.0056 | 0.0463 | 0.1307 | |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0022 | 0.0035 | 0.0119 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0211 | 0.2374 | 0.732 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.392 | 0.3899 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0026 | 0.0084 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.0379 | 0.1858 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0418 | 0.4935 | 0.4918 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.044 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0056 | 0.0463 | 0.0463 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0056 | 0.0463 | 0.0463 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.012 | 0.1245 | 0.1214 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.0379 | 0.1858 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.012 | 0.1245 | 0.1245 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.0379 | 0.311 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.012 | 0.1245 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.012 | 0.1245 | 0.1245 |
Echinococcus multilocularis | geranylgeranyl transferase type I beta subunit | 0.0022 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0152 | 0.0152 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0379 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0547 | 0.1685 |
Echinococcus multilocularis | geminin | 0.0336 | 0.392 | 0.392 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.012 | 0.1245 | 0.3753 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0152 | 0.1648 | 0.5063 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.012 | 0.1245 | 0.1245 |
Onchocerca volvulus | 0.0053 | 0.0415 | 0.1156 | |
Brugia malayi | Carboxylesterase family protein | 0.0134 | 0.1427 | 0.4379 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0136 | 0.0419 |
Echinococcus granulosus | RUN | 0.004 | 0.0257 | 0.0257 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.012 | 0.1245 | 0.3818 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0056 | 0.0463 | 0.0463 |
Onchocerca volvulus | 0.0026 | 0.0084 | 0.0121 | |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1648 | 0.508 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0026 | 0.0084 | 0.0084 |
Schistosoma mansoni | lamin | 0.0053 | 0.0415 | 0.0381 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0063 | 0.0547 | 0.0513 |
Leishmania major | lanosterol synthase, putative | 0.0138 | 0.1474 | 0.7408 |
Echinococcus multilocularis | cpg binding protein | 0.0061 | 0.0524 | 0.0524 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.012 | 0.1245 | 0.1245 |
Brugia malayi | ecdysteroid receptor | 0.0281 | 0.3243 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.0379 | 0.0345 |
Schistosoma mansoni | zinc finger protein | 0.0056 | 0.0463 | 0.0429 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0056 | 0.0463 | 0.0429 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.0084 | 0.2184 |
Plasmodium falciparum | amino acid transporter, putative | 0.0026 | 0.0084 | 0.2184 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0023 | 0.0045 | 0.0036 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0257 | 0.0223 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.0223 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0722 | 0.8709 | 0.8705 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0045 | 0.001 |
Echinococcus multilocularis | serotonin transporter | 0.0152 | 0.1648 | 0.1648 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.012 | 0.1245 | 0.384 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0026 | 0.0084 | 0.0049 |
Echinococcus granulosus | acetylcholinesterase | 0.0134 | 0.1427 | 0.1427 |
Schistosoma mansoni | lamin | 0.0053 | 0.0415 | 0.0381 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0251 | 0.2877 | 0.2877 |
Echinococcus multilocularis | FTZ F1 alpha | 0.012 | 0.1245 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Onchocerca volvulus | 0.004 | 0.0257 | 0.0664 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.0281 | 0.3243 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0152 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3243 | 1 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0045 | 0.0103 |
Trypanosoma brucei | geranylgeranyl transferase type II beta subunit, putative | 0.0022 | 0.0035 | 0.0119 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0722 | 0.8709 | 0.8709 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.016 | 0.1746 | 0.8781 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.012 | 0.1245 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.392 | 0.3899 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.012 | 0.1245 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0415 | 0.1278 |
Trichomonas vaginalis | set domain proteins, putative | 0.024 | 0.2732 | 1 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0026 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | doublecortin family protein | 0.004 | 0.0257 | 0.0794 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.0379 | 0.1136 |
Schistosoma mansoni | thyroid hormone receptor | 0.0251 | 0.2877 | 0.2852 |
Brugia malayi | nuclear receptor RXR | 0.0063 | 0.0547 | 0.1655 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.0379 | 0.0379 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.012 | 0.1245 | 0.384 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.0379 | 0.4992 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0547 | 0.1655 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.012 | 0.1245 | 0.3818 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.0045 | 0.0045 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0152 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.012 | 0.1245 | 0.3818 |
Schistosoma mansoni | loxhd1 | 0.004 | 0.0257 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.012 | 0.1245 | 0.3818 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0152 | 0.0434 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0257 | 0.0257 |
Echinococcus multilocularis | Rab geranylgeranyltransferase, beta subunit | 0.0022 | 0.0035 | 0.0035 |
Brugia malayi | Doublecortin family protein | 0.004 | 0.0257 | 0.076 |
Brugia malayi | conserved hypotetical protein | 0.0056 | 0.0463 | 0.1396 |
Loa Loa (eye worm) | DR-78 | 0.0056 | 0.0463 | 0.1427 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0112 | 0.0347 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0063 | 0.0547 | 0.1685 |
Onchocerca volvulus | 0.0152 | 0.1648 | 0.5011 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0111 | 0.1139 | 1 |
Echinococcus granulosus | geminin | 0.0336 | 0.392 | 0.392 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0132 | 0.1396 | 0.1396 |
Echinococcus multilocularis | RUN | 0.004 | 0.0257 | 0.0257 |
Onchocerca volvulus | 0.0058 | 0.0483 | 0.1369 | |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0077 | 0.0723 | 1 |
Schistosoma mansoni | lipoxygenase | 0.004 | 0.0257 | 0.0223 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.0045 | 0.001 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0077 | 0.0723 | 0.0723 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.012 | 0.1245 | 0.3818 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0058 | 0.0483 | 0.1488 |
Plasmodium vivax | amine transporter, putative | 0.0026 | 0.0084 | 0.2184 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.0379 | 0.0379 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.012 | 0.1245 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0409 | 0.0375 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0077 | 0.0723 | 0.0723 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0257 | 0.0257 |
Echinococcus multilocularis | acetylcholinesterase | 0.0134 | 0.1427 | 0.1427 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0152 | 0.1648 | 0.1618 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0026 | 0.0084 | 0.0049 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0026 | 0.0084 | 0.0049 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0078 | 0.024 |
Onchocerca volvulus | 0.012 | 0.1245 | 0.3753 | |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0012 | 0.0036 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.0379 | 0.1858 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0012 | 0.0036 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0077 | 0.0723 | 0.3603 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0547 | 0.1685 |
Onchocerca volvulus | 0.0026 | 0.0084 | 0.0121 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0152 | 0.1056 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0084 | 0.0223 |
Loa Loa (eye worm) | serotonin transporter b | 0.0152 | 0.1648 | 0.508 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0026 | 0.0084 | 0.0084 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0077 | 0.0723 | 0.069 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0022 | 0.0035 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0547 | 0.1685 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0112 | 0.1146 | 0.1146 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0025 | 0.0078 | 0.0078 |
Onchocerca volvulus | 0.004 | 0.0257 | 0.0664 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.012 | 0.1245 | 0.384 |
Loa Loa (eye worm) | steroid hormone receptor | 0.012 | 0.1245 | 0.384 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.012 | 0.1245 | 0.3818 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0045 | 0.001 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0045 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0056 | 0.0463 | 0.1307 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0026 | 0.0084 | 0.0084 |
Schistosoma mansoni | nuclear hormone receptor | 0.0056 | 0.0463 | 0.0429 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0134 | 0.1427 | 0.1427 |
Schistosoma mansoni | lipoxygenase | 0.0112 | 0.1146 | 0.1114 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Schistosoma mansoni | hypothetical protein | 0.0826 | 1 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0025 | 0.0078 | 0.0078 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.012 | 0.1245 | 0.1214 |
Onchocerca volvulus | 0.0026 | 0.0084 | 0.0121 | |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.0022 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0056 | 0.0463 | 0.1307 | |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0136 | 0.0385 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.012 | 0.1245 | 0.1245 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.0045 | 0.0045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.012 | 0.1245 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0257 | 0.0794 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1427 | 0.4399 |
Leishmania major | squalene monooxygenase-like protein | 0.0179 | 0.1986 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.004 | 0.0257 | 0.0257 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0026 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.012 | 0.1245 | 0.384 |
Brugia malayi | nuclear hormone receptor | 0.012 | 0.1245 | 0.3818 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0379 | 0.1273 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0077 | 0.0723 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0547 | 0.1685 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.0379 | 0.0379 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0056 | 0.0463 | 0.0463 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0045 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0066 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0257 | 0.0794 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.012 | 0.1245 | 0.1245 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0056 | 0.0463 | 0.0463 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0524 | 0.049 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0056 | 0.0463 | 0.1396 |
Brugia malayi | nuclear receptor NHR-88 | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0152 | 0.0117 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0056 | 0.0463 | 0.0463 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0022 | 0.0035 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Schistosoma mansoni | nuclear receptor | 0.0056 | 0.0463 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0066 | 0.0204 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0084 | 0.044 |
Brugia malayi | hypothetical protein | 0.004 | 0.0257 | 0.076 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0035 | 0.0119 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.012 | 0.1245 | 0.1245 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0379 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0112 | 0.1146 | 0.1146 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.0045 | 0.001 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.012 | 0.1245 | 0.3818 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0722 | 0.8709 | 0.8709 |
Loa Loa (eye worm) | CYP4Cod1 | 0.002 | 0.0012 | 0.0036 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.042 | 0.4967 | 0.495 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0084 | 0.044 |
Brugia malayi | tailless protein | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0026 | 0.0084 | 0.0084 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0063 | 0.0547 | 0.1655 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0056 | 0.0463 | 0.1427 |
Brugia malayi | hypothetical protein | 0.004 | 0.0257 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0415 | 0.1247 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0152 | 0.0152 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.012 | 0.1245 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Plasmodium falciparum | transporter, putative | 0.0026 | 0.0084 | 0.2184 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0379 | 0.1273 |
Brugia malayi | ecdysone receptor | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | hypothetical protein | 0.0132 | 0.1396 | 0.1366 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0056 | 0.0463 | 0.0463 |
Echinococcus granulosus | FTZ F1 alpha | 0.012 | 0.1245 | 0.1245 |
Onchocerca volvulus | 0.024 | 0.2732 | 0.8403 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.012 | 0.1245 | 0.1214 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0056 | 0.0463 | 0.1307 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0415 | 0.0415 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0063 | 0.0547 | 0.0547 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.016 | 0.1746 | 0.8781 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0022 | 0.0035 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0723 | 0.223 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.012 | 0.1245 | 0.1245 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0077 | 0.0723 | 0.0723 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0415 | 0.0381 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0063 | 0.0547 | 0.1655 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0415 | 0.0415 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.0379 | 0.1858 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0023 | 0.0045 | 0.0036 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0134 | 0.1427 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0524 | 0.049 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0023 | 0.0045 | 1 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0257 | 0.0223 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0045 | 0.0103 |
Echinococcus multilocularis | acetylcholinesterase | 0.0134 | 0.1427 | 0.1427 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.0379 | 0.0379 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0257 | 0.0223 |
Echinococcus granulosus | serotonin transporter | 0.0152 | 0.1648 | 0.1648 |
Schistosoma mansoni | polycystin 1-related | 0.004 | 0.0257 | 0.0223 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0134 | 0.1427 | 0.4399 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0063 | 0.0547 | 0.0547 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0084 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0077 | 0.0723 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0403 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.012 | 0.1245 | 0.3753 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.012 | 0.1245 | 0.3818 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0547 | 0.1685 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0152 | 0.1648 | 0.5 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0022 | 0.0035 | 0.0108 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.012 | 0.1245 | 0.384 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.0045 | 0.001 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.012 | 0.1245 | 0.3818 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.012 | 0.1245 | 0.1214 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0826 | 1 | 1 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0089 | 0.0861 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.012 | 0.1245 | 0.1245 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0152 | 0.1648 | 0.508 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0077 | 0.0723 | 0.069 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0077 | 0.0723 | 0.255 |
Echinococcus granulosus | acetylcholinesterase | 0.0134 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.0053 | 0.0415 | 0.1156 | |
Schistosoma mansoni | gliotactin | 0.0023 | 0.0045 | 0.001 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.012 | 0.1245 | 0.1245 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0077 | 0.0723 | 0.255 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0463 | 0.1396 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.0022 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0056 | 0.0463 | 0.1427 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.012 | 0.1245 | 0.3818 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0035 | 0.0119 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0463 | 0.1396 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0026 | 0.0084 | 0.0084 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.012 | 0.1245 | 0.3818 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0415 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0257 | 0.0257 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0483 | 0.0449 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0056 | 0.0463 | 0.0463 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0056 | 0.0463 | 0.1396 |
Echinococcus granulosus | geranylgeranyl transferase type I beta subunit | 0.0022 | 0.0035 | 0.0035 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0056 | 0.0463 | 0.1396 |
Echinococcus granulosus | cpg binding protein | 0.0061 | 0.0524 | 0.0524 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.012 | 0.1245 | 0.3818 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1648 | 0.508 |
Onchocerca volvulus | 0.0031 | 0.0152 | 0.0334 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.012 | 0.1245 | 0.3818 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.012 | 0.1245 | 0.1214 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0056 | 0.0463 | 0.1396 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0152 | 0.0117 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0026 | 0.0084 | 0.0084 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0122 | 0.0122 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.012 | 0.1245 | 0.3818 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0056 | 0.0463 | 0.0463 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.0379 | 0.1858 |
Loa Loa (eye worm) | carboxylesterase | 0.0134 | 0.1427 | 0.4399 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0045 | 0.001 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0152 | 0.0117 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0084 |
Echinococcus granulosus | carboxylesterase 5A | 0.0134 | 0.1427 | 0.1427 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0132 | 0.1396 | 0.1396 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.0045 | 0.0045 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0056 | 0.0463 | 0.0463 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0179 | 0.1986 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.012 | 0.1245 | 0.3818 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0415 | 0.1278 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0415 | 0.0415 |
Schistosoma mansoni | nuclear receptor | 0.0056 | 0.0463 | 0.0429 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0258 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0056 | 0.0463 | 0.1427 |
Schistosoma mansoni | thyroid hormone receptor | 0.0251 | 0.2877 | 0.2852 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0045 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0124 | 0.1302 | 0.1271 |
Brugia malayi | steroid hormone receptor | 0.012 | 0.1245 | 0.3818 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0077 | 0.0723 | 0.3603 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.012 | 0.1245 | 0.384 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0056 | 0.0463 | 0.0463 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0077 | 0.0723 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1427 | 0.4399 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.0045 | 0.0045 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.0379 | 0.1858 |
Brugia malayi | CXXC zinc finger family protein | 0.0058 | 0.0483 | 0.1458 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0152 | 0.1648 | 0.508 |
Echinococcus granulosus | lamin | 0.0053 | 0.0415 | 0.0415 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0077 | 0.0723 | 0.255 |
Schistosoma mansoni | nuclear hormone receptor | 0.0056 | 0.0463 | 0.0429 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0026 | 0.0084 | 0.0049 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.0045 | 0.0045 |
Brugia malayi | nuclear hormone receptor | 0.0056 | 0.0463 | 0.1396 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0028 | 0.0112 | 0.0312 |
Trypanosoma brucei | squalene monooxygenase, putative | 0.0179 | 0.1986 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0077 | 0.0723 | 0.2202 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.0045 | 0.0045 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0152 | 0.5246 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.0223 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0026 | 0.0084 | 0.0049 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0026 | 0.0084 | 0.0258 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0056 | 0.0463 | 0.0463 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.004 | 0.0257 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0056 | 0.0463 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0463 | 0.1427 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0415 | 0.0415 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.012 | 0.1245 | 0.1245 |
Brugia malayi | nuclear receptor NHR-88 | 0.012 | 0.1245 | 0.3818 |
Brugia malayi | Probable protein farnesyltransferase beta subunit, putative | 0.0022 | 0.0035 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0045 | 0.0138 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.012 | 0.1245 | 0.1245 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0026 | 0.0084 | 0.0084 |
Brugia malayi | nuclear receptor NHR-67 | 0.0056 | 0.0463 | 0.1396 |
Trypanosoma brucei | lanosterol synthase | 0.016 | 0.1746 | 0.8781 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0077 | 0.0723 | 0.3603 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0026 | 0.0084 | 0.0223 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0379 | 0.1858 |
Plasmodium falciparum | LCCL domain-containing protein | 0.004 | 0.0257 | 1 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0022 | 0.0035 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1245 | 0.384 |
Brugia malayi | Carboxylesterase family protein | 0.0134 | 0.1427 | 0.4379 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0152 | 0.0117 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 29.0929 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.