Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0182 | 0.0351 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0094 | 0.0422 | 0.2863 |
Mycobacterium ulcerans | hypothetical protein | 0.0259 | 0.1436 | 0.2331 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0048 | 0.0143 | 0.0416 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0182 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0213 | 0.1154 | 0.2275 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0051 | 0.0104 |
Brugia malayi | nuclear receptor NHR-88 | 0.0055 | 0.0182 | 0.0351 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0043 | 0.0087 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0094 | 0.0422 | 0.08 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0049 | 0.015 | 0.0461 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0099 | 0.0454 | 0.2314 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0069 | 0.027 | 0.0598 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0669 | 0.1314 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0259 | 0.1436 | 0.129 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0049 | 0.015 | 0.0805 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0069 | 0.027 | 0.0526 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.011 | 0.0519 | 0.1019 |
Echinococcus granulosus | tumor protein p63 | 0.0749 | 0.4442 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0092 | 0.0145 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0182 | 0.0399 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.0336 | 0.0655 |
Plasmodium vivax | hypothetical protein, conserved | 0.0259 | 0.1436 | 1 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0049 | 0.015 | 0.0327 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.0106 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0049 | 0.015 | 0.0805 |
Brugia malayi | hypothetical protein | 0.0154 | 0.0791 | 0.1557 |
Schistosoma mansoni | lamin | 0.0122 | 0.0598 | 0.1173 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0195 | 0.1042 | 0.2053 |
Brugia malayi | MH2 domain containing protein | 0.0042 | 0.0106 | 0.0201 |
Loa Loa (eye worm) | RNA binding protein | 0.0134 | 0.0669 | 0.1314 |
Brugia malayi | RNA binding protein | 0.0134 | 0.0669 | 0.1314 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0042 | 0.0106 | 0.0229 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.0745 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0049 | 0.015 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Brugia malayi | Pre-SET motif family protein | 0.0232 | 0.127 | 0.2504 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0621 | 0.3657 | 0.7229 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.5 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0049 | 0.015 | 0.0287 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0051 | 0.0251 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0319 | 0.1803 | 0.4052 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0049 | 0.015 | 0.0432 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0182 | 0.0351 |
Giardia lamblia | GTOR | 0.0049 | 0.015 | 0.3822 |
Toxoplasma gondii | ABC1 family protein | 0.0259 | 0.1436 | 1 |
Brugia malayi | TAR-binding protein | 0.0134 | 0.0669 | 0.1314 |
Echinococcus granulosus | Smad4 | 0.0042 | 0.0106 | 0.0229 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0259 | 0.1436 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0259 | 0.1436 | 0.2813 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.026 | 0.0576 |
Trichomonas vaginalis | esterase, putative | 0.0259 | 0.1436 | 0.2813 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0182 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0584 | 0.1146 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0066 | 0.0249 | 0.0483 |
Loa Loa (eye worm) | glutaminase 2 | 0.0849 | 0.5057 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.026 | 0.0506 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.026 | 0.0506 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0037 | 0.0074 | 0.0264 |
Echinococcus granulosus | tar DNA binding protein | 0.0134 | 0.0669 | 0.1495 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.0108 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0232 | 0.127 | 0.2504 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0051 | 0.0091 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.0336 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.0598 | 0.1173 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0055 | 0.0182 | 0.0399 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.004 | 0.0092 | 0.039 |
Brugia malayi | hypothetical protein | 0.0305 | 0.1715 | 0.3384 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0094 | 0.0422 | 0.2863 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0092 | 0.0145 |
Brugia malayi | MH2 domain containing protein | 0.0042 | 0.0106 | 0.0201 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0092 | 0.0145 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0105 | 0.0491 | 0.2539 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.0336 | 0.2255 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0055 | 0.0182 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Echinococcus granulosus | intermediate filament protein | 0.0122 | 0.0598 | 0.1336 |
Onchocerca volvulus | 0.0259 | 0.1436 | 0.9793 | |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0051 | 0.0091 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0037 | 0.0074 | 0.011 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.026 | 0.0576 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0052 | 0.0167 | 0.4292 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0084 | 0.0363 | 0.176 |
Schistosoma mansoni | smad | 0.0042 | 0.0106 | 0.0201 |
Schistosoma mansoni | thyroid hormone receptor | 0.0736 | 0.4358 | 0.8617 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0259 | 0.1436 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0669 | 0.1314 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0174 | 0.0914 | 0.18 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0182 | 0.0399 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0035 | 0.0033 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0055 | 0.0182 | 0.1212 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | thyroid hormone receptor | 0.0736 | 0.4358 | 0.8617 |
Onchocerca volvulus | 0.0033 | 0.0051 | 0.0314 | |
Brugia malayi | steroid hormone receptor | 0.0055 | 0.0182 | 0.0351 |
Echinococcus multilocularis | tumor protein p63 | 0.0749 | 0.4442 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0051 | 0.0104 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.026 | 0.0506 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0105 | 0.0491 | 0.0962 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0319 | 0.1803 | 0.3559 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0669 | 0.1314 |
Loa Loa (eye worm) | beta-lactamase | 0.0259 | 0.1436 | 0.2833 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0055 | 0.0182 | 0.0351 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0336 | 0.2255 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0669 | 0.1314 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0182 | 0.0351 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0259 | 0.1436 | 0.129 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0105 | 0.0491 | 0.0937 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0305 | 0.1715 | 0.3853 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0336 | 0.0655 |
Entamoeba histolytica | hypothetical protein | 0.0305 | 0.1715 | 1 |
Brugia malayi | beta-lactamase | 0.0259 | 0.1436 | 0.2833 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0182 | 0.0399 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0051 | 0.0091 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0037 | 0.0074 | 0.0519 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0049 | 0.015 | 0.0432 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0259 | 0.1436 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0319 | 0.1803 | 0.3559 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0029 | 0.0024 | 0.0038 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Echinococcus granulosus | FTZ F1 alpha | 0.0055 | 0.0182 | 0.0399 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0055 | 0.0182 | 0.0351 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0213 | 0.1154 | 0.2275 |
Loa Loa (eye worm) | glutaminase | 0.0849 | 0.5057 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0305 | 0.1715 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0213 | 0.1154 | 0.2275 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0736 | 0.4358 | 0.981 |
Echinococcus multilocularis | Smad4 | 0.0042 | 0.0106 | 0.0229 |
Schistosoma mansoni | hypothetical protein | 0.0681 | 0.4023 | 0.7954 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0681 | 0.4023 | 0.9054 |
Echinococcus multilocularis | smad | 0.0042 | 0.0106 | 0.0229 |
Brugia malayi | MH2 domain containing protein | 0.0621 | 0.3657 | 0.7229 |
Schistosoma mansoni | intermediate filament proteins | 0.0122 | 0.0598 | 0.1173 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0259 | 0.1436 | 0.129 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0056 | 0.0074 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0259 | 0.1436 | 0.2813 |
Echinococcus multilocularis | lamin | 0.0122 | 0.0598 | 0.1336 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0259 | 0.1436 | 0.129 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0051 | 0.0091 |
Trichomonas vaginalis | glutaminase, putative | 0.0849 | 0.5057 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0051 | 0.0091 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0182 | 0.0399 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Schistosoma mansoni | Smad4 | 0.0042 | 0.0106 | 0.0201 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0035 | 0.0033 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0092 | 0.0145 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0029 | 0.0024 | 0.0043 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0681 | 0.4023 | 0.9054 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0055 | 0.0182 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0055 | 0.0182 | 0.0399 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0259 | 0.1436 | 0.2833 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0259 | 0.1436 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0037 | 0.0074 | 0.0138 |
Brugia malayi | nuclear hormone receptor | 0.0055 | 0.0182 | 0.0351 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0042 | 0.0106 | 0.0229 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0042 | 0.0106 | 0.0201 |
Mycobacterium tuberculosis | Conserved protein | 0.0259 | 0.1436 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0092 | 0.0145 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0213 | 0.1154 | 0.2275 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0259 | 0.1436 | 0.2833 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0259 | 0.1436 | 0.2833 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0182 | 0.0351 |
Onchocerca volvulus | 0.0122 | 0.0598 | 0.4056 | |
Entamoeba histolytica | hypothetical protein | 0.0305 | 0.1715 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0259 | 0.1436 | 0.2331 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0042 | 0.0106 | 0.0201 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0042 | 0.0106 | 0.0201 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0134 | 0.0669 | 0.1314 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0182 | 0.0351 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0055 | 0.0182 | 0.1212 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.0106 | 0.0201 |
Trichomonas vaginalis | set domain proteins, putative | 0.0264 | 0.1466 | 0.2873 |
Loa Loa (eye worm) | Smad1 | 0.0042 | 0.0106 | 0.0201 |
Schistosoma mansoni | lamin | 0.0122 | 0.0598 | 0.1173 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0195 | 0.1042 | 0.2337 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0034 | 0.003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0073 | 0.0295 | 0.0548 |
Echinococcus multilocularis | musashi | 0.0122 | 0.0598 | 0.1336 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.026 | 0.0506 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0059 | 0.0209 | 0.046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0182 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0209 | 0.0404 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.0106 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.074 | 0.1456 |
Brugia malayi | ecdysteroid receptor | 0.0055 | 0.0182 | 0.0351 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0037 | 0.0074 | 0.0138 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0182 | 0.0351 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0122 | 0.0598 | 0.1173 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.026 | 0.0576 |
Echinococcus multilocularis | tar DNA binding protein | 0.0134 | 0.0669 | 0.1495 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0182 | 0.0399 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0094 | 0.0422 | 0.2863 |
Mycobacterium ulcerans | lipase LipD | 0.0259 | 0.1436 | 0.2331 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0086 | 0.0374 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0105 | 0.0491 | 0.3241 |
Brugia malayi | beta-lactamase family protein | 0.0259 | 0.1436 | 0.2833 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0182 | 0.0351 |
Brugia malayi | glutaminase DH11.1 | 0.0849 | 0.5057 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Onchocerca volvulus | 0.011 | 0.0519 | 0.3521 | |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0059 | 0.0209 | 0.046 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.026 | 0.0576 |
Onchocerca volvulus | 0.0259 | 0.1436 | 0.9793 | |
Brugia malayi | beta-lactamase family protein | 0.0259 | 0.1436 | 0.2833 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0669 | 0.1314 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0042 | 0.0106 | 0.0229 |
Entamoeba histolytica | hypothetical protein | 0.0305 | 0.1715 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0105 | 0.0491 | 0.3241 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.0106 | 0.0201 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0052 | 0.0167 | 0.0366 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0051 | 0.0251 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0055 | 0.0182 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.1436 | 0.2833 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0134 | 0.0669 | 0.1314 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.074 | 0.1456 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.026 | 0.0506 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0055 | 0.0182 | 0.0351 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0049 | 0.015 | 0.1045 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0067 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.026 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0038 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0305 | 0.1715 | 0.3853 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.004 | 0.0092 | 0.0641 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.009 | 0.0398 | 0.0778 |
Echinococcus granulosus | smad | 0.0042 | 0.0106 | 0.0229 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0051 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Mycobacterium leprae | conserved hypothetical protein | 0.0259 | 0.1436 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0094 | 0.0422 | 0.08 |
Schistosoma mansoni | coup transcription factor | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0055 | 0.0182 | 0.0351 |
Mycobacterium tuberculosis | Conserved protein | 0.0259 | 0.1436 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.027 | 0.0526 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0259 | 0.1436 | 0.2833 |
Echinococcus multilocularis | lamin dm0 | 0.0122 | 0.0598 | 0.1336 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0105 | 0.0491 | 0.0937 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0105 | 0.0491 | 0.0937 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0195 | 0.1042 | 0.2337 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.0106 | 0.0201 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0029 | 0.0024 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0195 | 0.0377 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0621 | 0.3657 | 0.7229 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.1715 | 0.3384 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0055 | 0.0182 | 0.1212 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0146 | 0.074 | 0.1456 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0182 | 0.0399 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.005 | 0.0062 |
Onchocerca volvulus | 0.0259 | 0.1436 | 0.9793 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0259 | 0.1436 | 0.129 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0259 | 0.1436 | 0.3225 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0038 | 0.0077 | 0.0436 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0055 | 0.0182 | 0.0351 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0055 | 0.0182 | 0.0399 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0049 | 0.015 | 0.0287 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0055 | 0.0182 | 0.0399 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0042 | 0.0106 | 0.0229 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0259 | 0.1436 | 0.2813 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0336 | 0.2255 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.026 | 0.0576 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0031 | 0.0038 | 0.0065 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0029 | 0.0024 | 0.0043 |
Brugia malayi | nuclear receptor RXR | 0.0029 | 0.0024 | 0.0038 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0055 | 0.0182 | 0.0351 |
Mycobacterium ulcerans | glutaminase | 0.0849 | 0.5057 | 1 |
Schistosoma mansoni | glutaminase | 0.0849 | 0.5057 | 1 |
Onchocerca volvulus | 0.0055 | 0.0182 | 0.1212 | |
Onchocerca volvulus | 0.0122 | 0.0598 | 0.4056 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0134 | 0.0669 | 0.1314 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0035 | 0.0033 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.015 | 0.0261 |
Onchocerca volvulus | 0.0154 | 0.0791 | 0.5382 | |
Echinococcus granulosus | peptidase Clp S14 family | 0.0052 | 0.0167 | 0.0366 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0024 | 0.0038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0182 | 0.0351 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0029 | 0.0024 | 0.0038 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0066 | 0.0249 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Brugia malayi | Smad1 | 0.0042 | 0.0106 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0182 | 0.0351 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0073 | 0.0295 | 0.0548 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0037 | 0.0074 | 0.011 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0037 | 0.0074 | 0.011 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0182 | 0.0399 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0024 | 0.0038 |
Echinococcus granulosus | lamin dm0 | 0.0122 | 0.0598 | 0.1336 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0049 | 0.015 | 0.1045 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0122 | 0.0598 | 0.1173 |
Schistosoma mansoni | nuclear hormone receptor | 0.0055 | 0.0182 | 0.0351 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0259 | 0.1436 | 0.3225 |
Loa Loa (eye worm) | intermediate filament protein | 0.0122 | 0.0598 | 0.1173 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0052 | 0.0167 | 0.107 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0094 | 0.0422 | 0.094 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.0336 | 0.0655 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.031 | 0.1748 | 0.3928 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0049 | 0.015 | 0.0327 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0051 | 0.0091 |
Onchocerca volvulus | 0.0264 | 0.1466 | 1 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0259 | 0.1436 | 0.2813 |
Entamoeba histolytica | hypothetical protein | 0.0084 | 0.0363 | 0.176 |
Brugia malayi | intermediate filament protein | 0.0122 | 0.0598 | 0.1173 |
Echinococcus granulosus | lamin | 0.0122 | 0.0598 | 0.1336 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0086 | 0.0374 | 0.1827 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0055 | 0.0182 | 0.0351 |
Mycobacterium tuberculosis | Conserved protein | 0.0259 | 0.1436 | 0.129 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.0745 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0077 | 0.0116 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0259 | 0.1436 | 0.2331 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0182 | 0.0351 |
Leishmania major | hypothetical protein, conserved | 0.0259 | 0.1436 | 1 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0049 | 0.015 | 0.0461 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.015 | 0.0261 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.015 | 0.0261 |
Mycobacterium leprae | Probable lipase LipE | 0.0259 | 0.1436 | 1 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0069 | 0.027 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0195 | 0.0377 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0182 | 0.0399 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0055 | 0.0182 | 0.0351 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0055 | 0.0182 | 0.0351 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.5 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0086 | 0.0374 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0791 | 0.1557 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0519 | 0.1019 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0305 | 0.1715 | 0.3384 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.026 | 0.0576 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0034 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0055 | 0.0182 | 0.0351 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0336 | 0.8928 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.026 | 0.0506 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0259 | 0.1436 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.026 | 0.0506 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0259 | 0.1436 | 0.2813 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0259 | 0.1436 | 0.129 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0319 | 0.1803 | 0.3559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.