Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0052 | 0.0577 | 0.0577 |
Schistosoma mansoni | acetylcholinesterase | 0.0052 | 0.0577 | 0.0577 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.7214 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.0577 | 0.08 |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.0577 | 0.0577 |
Onchocerca volvulus | 0.0052 | 0.0577 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0456 | 0.0456 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0456 | 0.0456 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0052 | 0.0577 | 0.0577 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.0577 | 0.08 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0099 | 0.0099 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0099 | 0.0099 |
Onchocerca volvulus | 0.0052 | 0.0577 | 1 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0052 | 0.0577 | 0.0577 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0099 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0456 | 0.0456 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0052 | 0.0577 | 0.08 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0099 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | acetylcholinesterase | 0.0308 | 1 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0052 | 0.0577 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0308 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0052 | 0.0577 | 0.0577 |
Loa Loa (eye worm) | carboxylesterase | 0.0308 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0577 | 0.0577 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0456 | 0.0456 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0052 | 0.0577 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0099 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0577 | 0.0577 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | neuroligin | 0.0052 | 0.0577 | 0.0577 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0456 | 0.0456 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0308 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0456 | 0.0456 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0099 | 0.0099 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0052 | 0.0577 | 0.0577 |
Onchocerca volvulus | 0.0052 | 0.0577 | 1 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.0577 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0099 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0099 | 0.0099 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0308 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0577 | 0.0577 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0052 | 0.0577 | 1 |
Schistosoma mansoni | gliotactin | 0.0052 | 0.0577 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0577 | 0.0577 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0052 | 0.0577 | 0.0577 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0308 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0577 | 0.0577 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0456 | 0.0456 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0456 | 0.0456 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0052 | 0.0577 | 1 |
Onchocerca volvulus | 0.0052 | 0.0577 | 1 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0308 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0308 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0308 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0308 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0456 | 0.0456 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.