Detailed information for compound 1263441

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 346.337 | Formula: C14H33Cl2N3O2
  • H donors: 2 H acceptors: 2 LogP: 3.25 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCC(C(=O)N(CCC[N+](C)(C)C)O)N.[Cl-].Cl
  • InChi: 1S/C14H32N3O2.2ClH/c1-5-6-7-8-10-13(15)14(18)16(19)11-9-12-17(2,3)4;;/h13,19H,5-12,15H2,1-4H3;2*1H/q+1;;/p-1
  • InChiKey: FTBIJYRGUATFHD-UHFFFAOYSA-M  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0207 0.1363
Mycobacterium ulcerans monoxygenase 0.0014 0.0009 0.0009
Trichomonas vaginalis pc-MYB2, putative 0.0057 0.0227 0.1703
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0389 0.1915 0.2665
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0035 0.0079
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0014 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.2028
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0131 0.1831
Trypanosoma brucei ISWI complex protein 0.0015 0.0015 0.0212
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0024 0.0054
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0139 0.1037
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0472
Loa Loa (eye worm) hypothetical protein 0.0119 0.0543 0.3573
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0131 0.4188
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus multilocularis geminin 0.0878 0.4404 1
Schistosoma mansoni hypothetical protein 0.033 0.1615 0.3667
Onchocerca volvulus 0.003 0.009 0.4076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis musashi 0.003 0.009 0.0194
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni ran 0.0021 0.0046 0.0105
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0212
Plasmodium falciparum thioredoxin reductase 0.0153 0.0718 1
Entamoeba histolytica disulphide oxidoreductase, putative 0.0014 0.0009 0.0243
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.0009 0.0009
Brugia malayi glutamate synthase 0.0014 0.0009 0.0069
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0018 0.0064
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0057 0.0421
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0244 0.0545
Echinococcus multilocularis snurportin 1 0.0311 0.1518 0.3441
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0208 0.2895
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0085 0.1191
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0172 0.2403
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0708 0.1607
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0014 0.0009 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0139 0.1048
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Echinococcus granulosus intermediate filament protein 0.003 0.009 0.0194
Schistosoma mansoni intermediate filament proteins 0.003 0.009 0.0204
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0035 0.0079
Loa Loa (eye worm) acetyltransferase 0.0151 0.0708 0.466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0139 0.0916
Entamoeba histolytica thioredoxin reductase, putative 0.0014 0.0009 0.0243
Brugia malayi hypothetical protein 0.0034 0.0111 0.0835
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0311 0.0698
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.0009 0.0057
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0014 0.0009 0.0243
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0035 0.007
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0133 0.0991
Schistosoma mansoni hypothetical protein 0.0036 0.0121 0.0275
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0035 0.0229
Echinococcus granulosus tar DNA binding protein 0.0138 0.0637 0.1438
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0052 0.0118
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus glutamate synthase 0.0014 0.0009 0.0011
Echinococcus granulosus dna polymerase kappa 0.004 0.0139 0.0307
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0208 0.2895
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Leishmania major hypothetical protein, conserved 0.0015 0.0015 0.0212
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0131 0.0865
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0035 0.0229
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0208 0.0278
Brugia malayi Dopamine receptor protein 2 0.0019 0.0035 0.0262
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0138 0.0637 0.4194
Plasmodium falciparum importin beta, putative 0.0029 0.0085 0.1191
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0139 0.0307
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0206 0.1553
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0179
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0076 0.056
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0035 0.007
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Brugia malayi sulfakinin receptor protein 0.0019 0.0035 0.0262
Loa Loa (eye worm) glutaminase 2 0.0273 0.1327 0.8743
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0244 0.0554
Brugia malayi neuropeptide F receptor 0.0019 0.0035 0.0262
Schistosoma mansoni ap endonuclease 0.0038 0.0131 0.0298
Echinococcus multilocularis serotonin receptor 0.0019 0.0035 0.007
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0463
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0014 0.0009 0.0128
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.0009 0.0243
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0035 0.0229
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0208 0.0749
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0217 0.1038 0.2351
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0024 0.0055
Schistosoma mansoni smad 0.0017 0.0024 0.0054
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0022 0.0169
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.035 0.1717 0.2387
Brugia malayi RNA binding protein 0.0138 0.0637 0.4796
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0035 0.0262
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0035 0.0079
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0208 0.2895
Toxoplasma gondii exonuclease III APE 0.0038 0.0131 0.0474
Onchocerca volvulus 0.0019 0.0035 0.1299
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0207 0.047
Echinococcus multilocularis dna polymerase eta 0.0066 0.0272 0.0609
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Brugia malayi G-protein coupled receptor 0.0019 0.0035 0.0262
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0035 0.007
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0014 0.0009 0.0128
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0142 0.4523
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0558 0.2774 0.2768
Echinococcus granulosus sex peptide receptor 0.0019 0.0035 0.007
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0463
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0035 0.1299
Brugia malayi Dopamine receptor protein 1 0.0019 0.0035 0.0262
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0131 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Brugia malayi chromobox protein homolog 3 0.0038 0.0133 0.1002
Brugia malayi RE15519p 0.0019 0.0035 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0019 0.026
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0014 0.0009 0.0033
Echinococcus granulosus chromobox protein 1 0.0069 0.0286 0.0641
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0035 0.007
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Trichomonas vaginalis MYB72, putative 0.0057 0.0227 0.1703
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0042 0.0279
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0139 0.0307
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0035 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Schistosoma mansoni importin beta-1 0.0029 0.0085 0.0194
Onchocerca volvulus 0.003 0.009 0.4076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Brugia malayi GnHR receptor homolog 0.0019 0.0035 0.0262
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0136 0.1024
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0558 0.2774 0.3865
Mycobacterium tuberculosis Probable reductase 0.035 0.1717 0.2387
Echinococcus granulosus GPCR family 2 0.0017 0.0022 0.0041
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0035 0.0079
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus granulosus geminin 0.0878 0.4404 1
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0207 0.047
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.0009 0.0009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0208
Echinococcus granulosus lamin dm0 0.003 0.009 0.0194
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0014 0.0009 0.006
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0148 0.1103
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0035 0.0262
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0035 0.007
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0207 0.047
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Plasmodium vivax glutathione reductase, putative 0.0153 0.0718 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0131 0.1831
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0286 0.2147
Plasmodium falciparum glutathione reductase 0.0153 0.0718 1
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0009 0.0011
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.026 0.058
Schistosoma mansoni lamin 0.003 0.009 0.0204
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0014 0.0009 0.0009
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0014 0.0009 0.0011
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0035 0.007
Onchocerca volvulus 0.0019 0.0035 0.1299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Leishmania major DNA polymerase eta, putative 0.0066 0.0272 0.3794
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Brugia malayi Bromodomain containing protein 0.0042 0.0151 0.1135
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.009 0.0591
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0591
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0058 0.0122
Brugia malayi glutaminase DH11.1 0.0273 0.1327 1
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0244 0.0545
Brugia malayi PHD-finger family protein 0.0029 0.0083 0.0623
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0208 0.0199
Schistosoma mansoni lamin 0.003 0.009 0.0204
Brugia malayi hypothetical protein 0.0074 0.0311 0.2346
Loa Loa (eye worm) hypothetical protein 0.0053 0.0206 0.1357
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0208 0.9081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Echinococcus multilocularis sex peptide receptor 0.0019 0.0035 0.007
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0139 0.0316
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0139 0.0182
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0038 0.0133 0.0876
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0035 0.0262
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Echinococcus granulosus hypothetical protein 0.0019 0.0035 0.007
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0058 0.0422
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0041
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0035 0.0229
Mycobacterium tuberculosis Probable oxidoreductase 0.0389 0.1915 0.2665
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0035 0.007
Echinococcus multilocularis glutamate synthase 0.0014 0.0009 0.0011
Echinococcus multilocularis thioredoxin glutathione reductase 0.0153 0.0718 0.1621
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0035 0.1299
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0035 0.007
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0172 0.0621
Leishmania major DNA polymerase kappa, putative 0.004 0.0139 0.1939
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0014 0.0009 0.0069
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0057 0.0229 0.0825
Onchocerca volvulus 0.003 0.0091 0.4126
Brugia malayi Serotonin receptor 0.0019 0.0035 0.0262
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0206 0.1553
Plasmodium falciparum glutathione reductase 0.0053 0.0208 0.2895
Brugia malayi AKH receptor 0.0019 0.0035 0.0262
Echinococcus granulosus dna polymerase eta 0.0066 0.0272 0.0609
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0172 0.1288
Loa Loa (eye worm) hypothetical protein 0.0046 0.0173 0.1138
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Onchocerca volvulus 0.0019 0.0035 0.1299
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0035 0.007
Leishmania major hypothetical protein, conserved 0.0053 0.0206 0.2871
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0244 0.0545
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Brugia malayi Smad1 0.0017 0.0024 0.0179
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0035 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0055
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0071 0.0297 0.1956
Schistosoma mansoni hypothetical protein 0.0311 0.1518 0.3448
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0573
Brugia malayi MH2 domain containing protein 0.0249 0.1205 0.9076
Trichomonas vaginalis glutaminase, putative 0.0273 0.1327 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0055
Echinococcus multilocularis tar DNA binding protein 0.0138 0.0637 0.1438
Brugia malayi Serotonin receptor 0.0019 0.0035 0.0262
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0014 0.0009 0.0011
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0035 0.0262
Trichomonas vaginalis apoptosis inducing factor, putative 0.0014 0.0009 0.0057
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0878 0.4404 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0139 0.0139
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.1205 0.7935
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0014 0.0009 0.0128
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.0009 0.0128
Onchocerca volvulus 0.0019 0.0035 0.1299
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0167
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0208 0.2895
Brugia malayi RNA, U transporter 1 0.0083 0.0359 0.2701
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0139 0.0316
Schistosoma mansoni ap endonuclease 0.0038 0.0131 0.0298
Loa Loa (eye worm) hypothetical protein 0.0038 0.0133 0.0873
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0229 0.1713
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0053 0.0206 0.1357
Giardia lamblia Myb 1-like protein 0.0057 0.0229 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0035 0.007
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.0009 0.0128
Schistosoma mansoni hypothetical protein 0.0878 0.4404 1
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0206 0.2871
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0058 0.0121
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0207 1
Leishmania major trypanothione reductase 0.0153 0.0718 1
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0014 0.0009 0.0128
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0179
Echinococcus multilocularis chromobox protein 1 0.0069 0.0286 0.0641
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0035 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0009 0.0021
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0286 0.1886
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0035 0.007
Mycobacterium ulcerans glutaminase 0.0273 0.1327 0.1327
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0035 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Brugia malayi neuropeptide F receptor 0.0019 0.0035 0.0262
Schistosoma mansoni histamine h1 receptor 0.0019 0.0035 0.0079
Brugia malayi Bromodomain containing protein 0.0079 0.0337 0.2541
Echinococcus multilocularis lamin 0.003 0.009 0.0194
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0172 0.0621
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0035 0.007
Schistosoma mansoni disulfide oxidoreductase 0.0014 0.0009 0.0021
Onchocerca volvulus 0.0019 0.0035 0.1299
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0035 0.0229
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0085 0.1191
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0014 0.0009 0.0128
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0035 0.0229
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.1518 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0041
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0212
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0057 0.0801
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0024 0.0045
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0014 0.0009 0.0243
Plasmodium falciparum ferrodoxin reductase-like protein 0.0014 0.0009 0.0128
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0142 0.6198
Echinococcus granulosus lamin 0.003 0.009 0.0194
Plasmodium vivax thioredoxin reductase, putative 0.0153 0.0718 1
Trichomonas vaginalis pc-MYB2, putative 0.0057 0.0227 0.1703
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0035 0.007
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.0009 0.0057
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Trypanosoma brucei NADH dehydrogenase 0.0014 0.0009 0.0128
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0014 0.0009 0.0128
Echinococcus multilocularis lamin dm0 0.003 0.009 0.0194
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0035 0.0229
Mycobacterium ulcerans hypothetical protein 0.0014 0.0009 0.0009
Loa Loa (eye worm) programmed cell death 8 0.0014 0.0009 0.006
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Echinococcus multilocularis serotonin receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0035 0.0079
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0035 0.007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0074 0.0311 0.0707
Onchocerca volvulus 0.0019 0.0035 0.1299
Onchocerca volvulus 0.0053 0.0207 1
Echinococcus multilocularis Smad4 0.0017 0.0024 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0024 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis C-MYB, putative 0.0057 0.0227 0.1703
Loa Loa (eye worm) Smad1 0.0017 0.0024 0.0156
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0311 0.0707
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0208 0.0208
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.035 0.1717 0.2387
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0004 0.0028
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0035 0.007
Schistosoma mansoni ran 0.0021 0.0046 0.0105
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0024 0.0156
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus orexin receptor type 2 0.0019 0.0035 0.007
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0014 0.0009 0.0011
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0052 0.0109
Brugia malayi TAR-binding protein 0.0138 0.0637 0.4796
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Trypanosoma brucei unspecified product 0.0027 0.0076 0.1066
Loa Loa (eye worm) RNA binding protein 0.0138 0.0637 0.4194
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0646
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0208 0.1555
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0046 0.0302
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0131 0.1831
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0024 0.0045
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0131 0.0131
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0208 0.2895
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0076 0.056
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0014 0.0009 0.0057
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0096
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0035 0.007
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0286 0.2147
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.0563
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0022 0.0169
Leishmania major importin beta-1 subunit, putative 0.0024 0.0057 0.0801
Loa Loa (eye worm) hypothetical protein 0.0053 0.0207 0.1363
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0208 0.2895
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0311 0.0698
Schistosoma mansoni chromobox protein 0.0069 0.0286 0.065
Mycobacterium ulcerans ferredoxin reductase 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0066 0.0272 0.1793
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0708 0.533
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0035 0.0262
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0131 0.5744
Mycobacterium ulcerans short chain dehydrogenase 0.0546 0.2711 0.2711
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Leishmania major DNA polymerase eta, putative 0.0038 0.0133 0.1855
Toxoplasma gondii thioredoxin reductase 0.0153 0.0718 0.2586
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus serotonin receptor 0.0019 0.0035 0.007
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0148
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0389 0.1915 0.2665
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Brugia malayi intermediate filament protein 0.003 0.009 0.0676
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0674 0.1523
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0014 0.0009 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0035 0.0079
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0172 0.0382
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) glutaminase 0.0273 0.1327 0.8743
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1421 0.7163 1
Echinococcus multilocularis GPCR, family 2 0.0017 0.0022 0.0041
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0131 0.0122
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.035 0.1717 0.2387
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0148 0.7014
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0011 0.0015
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0646
Schistosoma mansoni zinc finger protein 0.0015 0.0015 0.0034
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0009 0.0011
Echinococcus granulosus bloom syndrome protein 0.0024 0.0058 0.0121
Brugia malayi Importin beta-1 subunit 0.0029 0.0085 0.0644
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0035 0.007
Brugia malayi hypothetical protein 0.0053 0.0206 0.1552
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0306
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0021 0.0042 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0133 0.0991
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0035 0.0229
Echinococcus multilocularis smad 0.0017 0.0024 0.0044
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0011 0.0015
Echinococcus multilocularis zinc finger protein 0.0023 0.0056 0.0117
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.1445
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0207 0.0461
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0131 0.0122
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.0009 0.0128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.009 0.0676
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0054
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0206 0.1357
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0272 0.3794
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0244 0.0545
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0179
Toxoplasma gondii selenide, water dikinase 0.0014 0.0009 0.0033
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0085 0.0185
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0208 0.0199
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0206 0.2871
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0009 0.0128
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0035 0.007
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0338
Brugia malayi Thioredoxin reductase 0.0153 0.0718 0.5405
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0133 0.1855
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) RecQ helicase 0.0024 0.0058 0.0379
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.0009 0.0069
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0208 0.2895
Echinococcus granulosus zinc finger protein 0.0023 0.0056 0.0117
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0035 0.007
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.0009 0.0243
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.0021
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0208 0.0749
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Trypanosoma brucei trypanothione reductase 0.0153 0.0718 1
Loa Loa (eye worm) MBCTL1 0.006 0.0244 0.1608
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0019 0.0143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0133 0.048
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0153 0.0718 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0139 0.4437
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0009 0.0128
Brugia malayi ORL1-like opioid receptor 0.0019 0.0035 0.0262
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0052 0.0109
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0208 0.1555
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0035 0.007
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0058 0.0422
Echinococcus granulosus fmrfamide receptor 0.0019 0.0035 0.007
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0035 0.0079
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0139 0.1939
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0057
Brugia malayi mbt repeat family protein 0.0053 0.0207 0.1558
Brugia malayi putative neuropeptide receptor 0.0019 0.0035 0.0262
Brugia malayi Heterochromatin protein 1 0.0069 0.0286 0.2157
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0014 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0035 0.007
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0208 0.1565
Echinococcus granulosus thioredoxin glutathione reductase 0.0153 0.0718 0.1621
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0035 0.0229
Entamoeba histolytica hypothetical protein 0.0024 0.0057 0.1803
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0208 0.2895
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0148 0.1103
Brugia malayi Melatonin receptor type 1A 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0797
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0153 0.0718 0.099
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.0009 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0054
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0014 0.0009 0.0009
Treponema pallidum NADH oxidase 0.0053 0.0208 0.0199
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0035 0.007
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0035 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0131 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Onchocerca volvulus 0.0019 0.0035 0.1299
Schistosoma mansoni glutaminase 0.0273 0.1327 0.3014
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0043 0.0599
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0035 0.0079
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0035 0.007
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0139 0.1037
Echinococcus granulosus neuropeptide receptor 0.0019 0.0035 0.007
Echinococcus granulosus Smad4 0.0017 0.0024 0.0044
Brugia malayi RNA recognition motif domain containing protein 0.0138 0.0637 0.4796
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0085 0.0308
Schistosoma mansoni hypothetical protein 0.0024 0.0058 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0057 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Echinococcus granulosus importin subunit beta 1 0.0029 0.0085 0.0185
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0035 0.007
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0558 0.2774 0.2774
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0058 0.0122
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0014 0.0009 0.0009
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0142 0.1976
Brugia malayi Dopamine receptor 0.0019 0.0035 0.0262
Echinococcus granulosus somatostatin receptor 0.0019 0.0035 0.007
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0136 0.1024
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.026 0.058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0024 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Mycobacterium tuberculosis Probable dehydrogenase 0.035 0.1717 0.2387
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1421 0.7163 1
Trypanosoma brucei unspecified product 0.0027 0.0076 0.1066
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0131 0.1831
Trypanosoma brucei unspecified product 0.004 0.0139 0.1939
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis somatostatin receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) intermediate filament protein 0.003 0.009 0.0591
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0206 0.0743
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.0009 0.0128
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0244 0.1839
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0024 0.0045
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Giardia lamblia Glutamate synthase 0.0014 0.0009 0.04
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.0009 0.0057
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0121 0.0912
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0272 0.3794
Mycobacterium tuberculosis Putative ferredoxin reductase 0.035 0.1717 0.2387
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Onchocerca volvulus 0.0019 0.0035 0.1299
Leishmania major NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.012 0.0263
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0014 0.0009 0.0243
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.035 0.1717 0.2387
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0024 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0207 0.0461
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0206 0.2871
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Trichomonas vaginalis C-MYB, putative 0.0057 0.0227 0.1703
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0708 0.1599
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0208 0.0208
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0208 0.2895
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Trichomonas vaginalis MYB3r3, putative 0.0057 0.0227 0.1703
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Mycobacterium tuberculosis Probable oxidoreductase 0.0546 0.2711 0.3777
Giardia lamblia Thioredoxin reductase 0.0014 0.0009 0.04
Brugia malayi larval opioid receptor 0.0019 0.0035 0.0262
Echinococcus granulosus neuropeptide receptor 0.0019 0.0035 0.007
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0139 0.0182
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Plasmodium vivax importin-beta 2, putative 0.0029 0.0085 0.1191
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus granulosus snurportin 1 0.0311 0.1518 0.3441
Onchocerca volvulus 0.0019 0.0035 0.1299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus smad 0.0017 0.0024 0.0044
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0035 0.007
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0131 0.0979
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0131 0.0979
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Trichomonas vaginalis MYB, putative 0.0057 0.0229 0.1713
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0179
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0035 0.007
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0096
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0389 0.1915 0.2665
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Echinococcus granulosus allatostatin A receptor 0.0019 0.0035 0.007
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0272 0.2051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Mycobacterium ulcerans glutamate synthase subunit beta 0.0014 0.0009 0.0009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0022 0.0148
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0159
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0024 0.0045
Brugia malayi G-protein coupled receptor 0.0019 0.0035 0.0262
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0207 0.0461
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0208 0.0199
Brugia malayi CHD4 protein 0.0013 0.0004 0.0032
Brugia malayi glutathione reductase 0.0153 0.0718 0.5405
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0014 0.0009 0.0011
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0035 0.0079
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0349
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0172 0.1288
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0014 0.0009 0.0009
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0009 0.0011
Giardia lamblia DINP protein human, muc B family 0.004 0.0139 0.6081
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0057 0.0421
Plasmodium vivax ferrodoxin reductase, putative 0.0014 0.0009 0.0128
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0014 0.0009 0.0033
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0032 0.0073
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0014 0.0009 0.0011
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0024 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0131 0.0171
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0208 0.2895
Mycobacterium ulcerans NADH dehydrogenase 0.0014 0.0009 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0035 0.007
Schistosoma mansoni bromodomain containing protein 0.0067 0.0278 0.0631
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0058 0.0434
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Schistosoma mansoni myosin xvIII 0.0019 0.0035 0.0079
Brugia malayi mbt repeat family protein 0.0053 0.0207 0.1558
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0229 0.1713
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Schistosoma mansoni Smad4 0.0017 0.0024 0.0054
Brugia malayi G protein-coupled receptor 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0072
Onchocerca volvulus 0.0019 0.0035 0.1299
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0598
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Plasmodium falciparum thioredoxin reductase 0.0053 0.0208 0.2895
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0035 0.0079
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0131 0.1831
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0019 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni chromobox protein 0.0069 0.0286 0.065
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0014 0.0009 0.04
Schistosoma mansoni zinc finger protein 0.0023 0.0056 0.0126
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0558 0.2774 1
Schistosoma mansoni adenoreceptor 0.0019 0.0035 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0131 0.1831
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0024 0.0055
Echinococcus multilocularis chromobox protein 1 0.0069 0.0286 0.0641
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0024 0.0044
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0009 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0208 0.2895
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0217 0.1038 0.2351
Mycobacterium ulcerans dehydrogenase 0.0014 0.0009 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0139 0.0139
Echinococcus multilocularis dna polymerase kappa 0.004 0.0139 0.0307
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0131 0.099
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.012 0.0263
Loa Loa (eye worm) hypothetical protein 0.0044 0.0163 0.1074
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.1205 0.7935
Echinococcus granulosus chromobox protein 1 0.0069 0.0286 0.0641
Schistosoma mansoni DNA polymerase eta 0.0066 0.0272 0.0618
Loa Loa (eye worm) thioredoxin reductase 0.0153 0.0718 0.4726
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0035 0.007
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0035 0.007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0035 0.007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0208 0.2895
Loa Loa (eye worm) TAR-binding protein 0.0138 0.0637 0.4194
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0208 0.2895
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0035 0.007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.1608
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0035 0.007
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0646
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.0009 0.0057
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0133 0.6263
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0014 0.0009 0.0011
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0035 0.007
Loa Loa (eye worm) glutathione reductase 0.0153 0.0718 0.4726
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0207 0.0461
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 500 uM Inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C after 100 seconds ChEMBL. 21071231
LD50 (ADMET) = 100 uM Cytotoxicity against human A549 cells after 24 hrs by MTT assay ChEMBL. 21071231

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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