Detailed information for compound 1263452

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 615.681 | Formula: C32H33F4N3O3S
  • H donors: 2 H acceptors: 4 LogP: 6.07 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#C[C@H](C1(CC1)c1ccccc1)NC(=O)[C@H](CC(F)(C)C)N[C@H](C(F)(F)F)c1ccc(cc1)c1ccc(cc1)S(=O)(=O)C
  • InChi: 1S/C32H33F4N3O3S/c1-30(2,33)19-26(29(40)39-27(20-37)31(17-18-31)24-7-5-4-6-8-24)38-28(32(34,35)36)23-11-9-21(10-12-23)22-13-15-25(16-14-22)43(3,41)42/h4-16,26-28,38H,17-19H2,1-3H3,(H,39,40)/t26-,27+,28-/m0/s1
  • InChiKey: ULPVFBNSZZFPIE-IARZGTGTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin B Starlite/ChEMBL References
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL References
Homo sapiens cathepsin F Starlite/ChEMBL References
Homo sapiens cathepsin L Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin B-like cysteine proteinase Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni SmCB2 peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin B-like protease (Precursor), related Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum ko:K01363 cathepsin B [EC3.4.22.1], putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei gambiense cysteine peptidase C (CPC), putative,CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum dipeptidyl aminopeptidase 1 cathepsin B 339 aa 368 aa 26.9 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin L 333 aa 359 aa 30.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.4835 0.8549
Entamoeba histolytica cysteine proteinase 1, putative 0.0043 0.0313 0.1817
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0313 0.1817
Echinococcus granulosus cathepsin b 0.018 0.5656 0.943
Trypanosoma cruzi cysteine proteinase, putative 0.0043 0.0313 0.0553
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0313 0.1817
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.4835 0.8062
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0761 0.442
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0752 0.1254
Loa Loa (eye worm) hypothetical protein 0.0079 0.1721 0.3044
Echinococcus multilocularis cysteine protease 0.0079 0.1721 0.287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0761 0.442
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0043 0.0313 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0079 0.1721 0.287
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0079 0.1721 0.287
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.018 0.5656 0.5656
Leishmania major cysteine peptidase A (CPA) 0.0079 0.1721 0.436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Onchocerca volvulus Cathepsin L homolog 0.0079 0.1721 0.7133
Schistosoma mansoni alpha-glucosidase 0.0136 0.397 0.397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.7378 0.5
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0493 0.0872
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Trypanosoma cruzi cysteine peptidase, putative 0.0043 0.0313 0.0553
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Loa Loa (eye worm) MBCTL1 0.0054 0.0752 0.133
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.3948 0.698
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0079 0.1721 0.287
Leishmania major cathepsin L-like protease 0.0079 0.1721 0.436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0752 0.133
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0416 0.0736
Brugia malayi mbt repeat family protein 0.0048 0.0493 0.0872
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0493 0.0493
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.1302 0.1302
Leishmania major cathepsin L-like protease 0.0079 0.1721 0.436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0313 0.1817
Leishmania major cathepsin L-like protease 0.0136 0.3948 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0075 0.1579 0.2791
Loa Loa (eye worm) ctsf protein 0.0079 0.1721 0.3044
Echinococcus granulosus cathepsin l cysteine peptidase 0.0079 0.1721 0.287
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0313 0.0553
Giardia lamblia Cathepsin B precursor 0.0068 0.1302 0.5
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Brugia malayi mbt repeat family protein 0.0048 0.0493 0.0872
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0493 0.0822
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi Papain family cysteine protease containing protein 0.0079 0.1721 0.3044
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0752 0.0752
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0079 0.1721 1
Schistosoma mansoni alpha-glucosidase 0.0136 0.397 0.397
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0079 0.1721 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0416 0.0416
Toxoplasma gondii cathepsin CPL 0.0079 0.1721 1
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Onchocerca volvulus Cathepsin F homolog 0.0079 0.1721 0.7133
Brugia malayi Cathepsin L-like cysteine proteinase 0.0055 0.0761 0.1345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0416 0.0694
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0493 0.0822
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0068 0.1302 0.2302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0761 0.442
Echinococcus multilocularis cathepsin L 0.0043 0.0313 0.0521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Echinococcus granulosus cathepsin L 0.0043 0.0313 0.0521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0079 0.1721 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.5997 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0111 0.2987 0.5282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.018 0.5656 0.5656
Brugia malayi Cathepsin L-like precursor 0.0055 0.0761 0.1345
Onchocerca volvulus 0.0079 0.1721 0.7133
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Onchocerca volvulus Cathepsin L homolog 0.0079 0.1721 0.7133
Onchocerca volvulus 0.0079 0.1721 0.7133
Loa Loa (eye worm) cathepsin B 0.0068 0.1302 0.2302
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0761 0.0761
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Giardia lamblia Cathepsin B precursor 0.0068 0.1302 0.5
Onchocerca volvulus 0.0079 0.1721 0.7133
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0752 0.1254
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Echinococcus multilocularis cathepsin b 0.018 0.5656 0.943
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Schistosoma mansoni cathepsin F (C01 family) 0.0079 0.1721 0.1721
Trypanosoma cruzi cysteine peptidase, putative 0.0079 0.1721 0.3044
Brugia malayi cathepsin L-like precursor 0.0055 0.0761 0.1345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Onchocerca volvulus 0.0079 0.1721 0.7133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Echinococcus granulosus cathepsin l1 0.0079 0.1721 0.287
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1721 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0043 0.0313 0.0313
Leishmania major cathepsin L-like protease 0.0079 0.1721 0.436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Echinococcus granulosus cysteine protease 0.0043 0.0313 0.0521
Plasmodium vivax vivapain-2 0.0079 0.1721 1
Toxoplasma gondii cathepsin B 0.0068 0.1302 0.7563
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0416 0.0694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0313 0.1817
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0752 0.1254
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0416 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi cathepsin B-like cysteine proteinase 0.018 0.5656 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0493 0.0872
Loa Loa (eye worm) fibroinase 0.0079 0.1721 0.3044
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.4835 0.8549
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.4835 0.8062
Leishmania major cathepsin L-like protease 0.0079 0.1721 0.436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Brugia malayi Cathepsin L-like precursor 0.0079 0.1721 0.3044
Entamoeba histolytica cysteine protease, putative 0.0079 0.1721 1
Onchocerca volvulus 0.0079 0.1721 0.7133
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0079 0.1721 0.287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0313 0.1817
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0493 0.0822
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.018 0.5656 0.5656
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0493 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Plasmodium vivax vivapain-2 0.0079 0.1721 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0761 0.1345
Onchocerca volvulus 0.0055 0.0761 0.1556
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0493 0.0822
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1721 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0752 0.1254
Echinococcus multilocularis cathepsin b 0.018 0.5656 0.943
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.3948 0.698
Echinococcus granulosus cathepsin L cysteine protease 0.0043 0.0313 0.0521
Giardia lamblia Cathepsin B precursor 0.0068 0.1302 0.5
Echinococcus granulosus cathepsin b 0.018 0.5656 0.943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Entamoeba histolytica cysteine proteinase 2 0.0043 0.0313 0.1817
Brugia malayi Cathepsin L-like precursor 0.0055 0.0761 0.1345
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.5997 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0416 0.0416
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Trypanosoma brucei cysteine peptidase C (CPC) 0.0068 0.1302 0.3298
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0068 0.1302 0.3298
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0493 0.0493
Echinococcus granulosus cathepsin L cysteine proteinase 0.0079 0.1721 0.287
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0079 0.1721 1
Loa Loa (eye worm) hypothetical protein 0.018 0.5656 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.018 0.5656 0.5656
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.4835 0.8062
Onchocerca volvulus 0.0092 0.2215 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0079 0.1721 1
Leishmania major cathepsin L-like protease 0.0136 0.3948 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0079 0.1721 0.3044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0043 0.0313 0.0792
Echinococcus granulosus cathepsin l1 0.0055 0.0761 0.1269
Leishmania major cathepsin L-like protease 0.0079 0.1721 0.436
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0043 0.0313 0.0553
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.3948 0.698
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0416 0.0416
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0068 0.1302 0.7563
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Leishmania major cathepsin L-like protease 0.0136 0.3948 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0043 0.0313 0.0313
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.3948 0.698
Loa Loa (eye worm) hypothetical protein 0.0054 0.0752 0.133
Echinococcus multilocularis cysteine protease 0.0079 0.1721 0.287
Trypanosoma cruzi cysteine protease, putative 0.0043 0.0313 0.0553
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0079 0.1721 0.3044
Trypanosoma cruzi cysteine proteinase, putative 0.0043 0.0313 0.0553
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0416 0.0694
Onchocerca volvulus 0.0079 0.1721 0.7133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0043 0.0313 0.0792
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Schistosoma mansoni cathepsin F (C01 family) 0.0079 0.1721 0.1721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1721 1
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0313 0.1817
Entamoeba histolytica cysteine protease, putative 0.0043 0.0313 0.1817
Loa Loa (eye worm) hypothetical protein 0.0055 0.0761 0.1345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0079 0.1721 1
Onchocerca volvulus 0.0079 0.1721 0.7133
Loa Loa (eye worm) cysteine protease 0.0079 0.1721 0.3044
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0416 0.0694
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0313 0.0553
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.018 0.5656 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.3948 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0761 0.1345

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10000 nM Inhibition of Trypanosoma cruzi Cruzipain ChEMBL. 21041084
IC50 (binding) > 10000 nM Inhibition of human Cat B in HepG2 cells ChEMBL. 21041084
IC50 (binding) > 10000 nM Inhibition of human Cat F expressed in rabbit HIG82 cells ChEMBL. 21041084
IC50 (binding) > 10000 nM Inhibition of human Cat L ChEMBL. 21041084

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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