Detailed information for compound 1267245

Basic information

Technical information
  • TDR Targets ID: 1267245
  • Name: (3aS,6S,6aS)-4-methylsulfonyl-1-[(Z)-4-piperi din-1-ylbut-2-enoyl]-6-propan-2-yl-3,3a,6,6a- tetrahydro-2H-pyrrolo[2,3-d]pyrrol-5-one
  • MW: 397.532 | Formula: C19H31N3O4S
  • H donors: 0 H acceptors: 4 LogP: 1.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC([C@H]1[C@@H]2N(CC[C@@H]2N(C1=O)S(=O)(=O)C)C(=O)/C=C\CN1CCCCC1)C
  • InChi: 1S/C19H31N3O4S/c1-14(2)17-18-15(22(19(17)24)27(3,25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20/h7-8,14-15,17-18H,4-6,9-13H2,1-3H3/b8-7-/t15-,17-,18+/m0/s1
  • InChiKey: NDNKNUMSTIMSHQ-XCVXUXQRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3aS,6S,6aS)-6-isopropyl-4-methylsulfonyl-1-[(Z)-4-(1-piperidyl)but-2-enoyl]-3,3a,6,6a-tetrahydro-2H-pyrrolo[2,3-d]pyrrol-5-one
  • (3aS,6S,6aS)-6-isopropyl-4-methylsulfonyl-1-[(Z)-1-oxo-4-(1-piperidyl)but-2-enyl]-3,3a,6,6a-tetrahydro-2H-pyrrolo[2,3-d]pyrrol-5-one
  • (3aS,6S,6aS)-6-isopropyl-4-mesyl-1-[(Z)-4-piperidinobut-2-enoyl]-3,3a,6,6a-tetrahydro-2H-pyrrolo[2,3-d]pyrrol-5-one
  • Tocris-1959
  • NCGC00025326-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens regulator of G-protein signaling 4 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Echinococcus granulosus expressed protein Get druggable targets OG5_141764 All targets in OG5_141764
Echinococcus multilocularis expressed protein Get druggable targets OG5_141764 All targets in OG5_141764
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0039 0.0038 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Giardia lamblia Fructose-bisphosphate aldolase 0.0321 0.1126 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0106 0.0296 0.0295
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.004 0.0042 0.004
Onchocerca volvulus Peroxidasin homolog 0.0048 0.0075 0.0106
Echinococcus granulosus titin 0.0048 0.0075 0.0073
Echinococcus granulosus tyrosine protein kinase Src42A 0.0155 0.0488 0.0486
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) TK/EPH protein kinase 0.0135 0.041 0.041
Loa Loa (eye worm) TK protein kinase 0.0213 0.0708 0.0708
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0196 0.0644 0.0644
Brugia malayi jmjC domain containing protein 0.0061 0.0123 0.0123
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0037 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0749 0.0749
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0037 0.0035
Loa Loa (eye worm) SRC-1 0.025 0.0853 0.0853
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Brugia malayi Pre-SET motif family protein 0.0044 0.0057 0.0057
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0037 0.0035
Echinococcus granulosus tyrosine protein kinase Blk 0.0221 0.0742 0.074
Echinococcus multilocularis dual specificity protein kinase clk2 0.025 0.0854 0.0852
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0159 0.0762
Echinococcus multilocularis transfer RNA-Thr 0.0066 0.0143 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0196 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Echinococcus multilocularis thyroid hormone receptor alpha 0.0196 0.0644 0.0643
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0037 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.015 0.015
Echinococcus multilocularis lamin 0.0057 0.0107 0.0106
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0118 0.0343 0.0341
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Schistosoma mansoni cell adhesion molecule 0.0068 0.015 0.015
Echinococcus multilocularis tyrosine protein kinase csk 0.0066 0.0143 0.0141
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.1033 0.387 0.387
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0038 0.0255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Brugia malayi ephrin receptor 1 precursor 0.0092 0.0242 0.0242
Schistosoma mansoni ephrin receptor 0.0068 0.0151 0.0151
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0047 0.0045
Echinococcus multilocularis cyclin dependent kinase 0.0223 0.0749 0.0747
Leishmania major protein kinase, putative 0.0074 0.0175 0.0355
Schistosoma mansoni tensin 0.004 0.0042 0.0042
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.007 0.0158 0.0156
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0066 0.0143 0.0143
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0037 0.0035
Schistosoma mansoni nuclear receptor 0.0092 0.0245 0.0245
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.007 0.0159 0.0315
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0118 0.0343 0.0341
Schistosoma mansoni zinc finger protein 0.0092 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0038 0.0172
Schistosoma mansoni netrin receptor unc5 0.0082 0.0205 0.0205
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0037 0.0052
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0037 0.0035
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.1081 0.4056 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.031 0.6141
Schistosoma mansoni titin 0.0058 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.015 0.015
Echinococcus multilocularis tyrosine protein kinase 0.0066 0.0143 0.0141
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0057 0.0057
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0037 0.0031 0.0044
Mycobacterium tuberculosis Probable reductase 0.0108 0.0306 0.3515
Echinococcus granulosus mitogen activated protein kinase 14 0.0134 0.0406 0.0404
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0066 0.0143 0.108
Echinococcus granulosus tyrosine kinase 0.0066 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trypanosoma brucei polo-like protein kinase 0.0109 0.031 0.0691
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0153 0.0153
Loa Loa (eye worm) TK/EGFR protein kinase 0.2624 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0196 0.0644 0.0643
Echinococcus granulosus c src tyrosine kinase 0.0134 0.0407 0.0405
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0104 0.0288 0.0286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0344 0.1216 0.1216
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus granulosus tensin 0.004 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0017 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0307 0.1485
Brugia malayi beta-lactamase family protein 0.0039 0.0038 0.0038
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.005 0.0082 0.039
Onchocerca volvulus 0.0038 0.0037 0.0052
Loa Loa (eye worm) hypothetical protein 0.0068 0.015 0.015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0037 0.0035
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trypanosoma cruzi protein kinase, putative 0.0066 0.0143 0.0276
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0066 0.0143 0.0141
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus dual specificity 0.0367 0.1302 0.13
Brugia malayi nuclear receptor NHR-88 0.0196 0.0644 0.0644
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.1302 0.1302
Loa Loa (eye worm) hypothetical protein 0.0041 0.0047 0.0047
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0033 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0134 0.0407 0.0405
Echinococcus multilocularis kinase suppressor of Ras 1 0.0066 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0104 0.0288 0.0288
Schistosoma mansoni cell adhesion molecule 0.0298 0.1038 0.1038
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0068 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0118 0.0343 0.0343
Schistosoma mansoni polycystin 1-related 0.004 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.034 0.1198 0.1198
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni rab6-interacting 0.004 0.0041 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0113 0.0538
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0472 0.0472
Plasmodium falciparum glutathione reductase 0.0047 0.0072 0.0601
Schistosoma mansoni suppressor of cytokine signaling 0.004 0.0042 0.0042
Echinococcus granulosus hypothetical protein 0.004 0.0042 0.004
Schistosoma mansoni hypothetical protein 0.0081 0.0203 0.0203
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0057 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni hypothetical protein 0.0066 0.0143 0.0143
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Brugia malayi neuropeptide F receptor 0.0038 0.0037 0.0037
Schistosoma mansoni ephrin receptor 0.012 0.0353 0.0353
Schistosoma mansoni hypothetical protein 0.034 0.1198 0.1198
Schistosoma mansoni coup transcription factor 0.0196 0.0644 0.0644
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.031 0.031
Plasmodium vivax protein kinase Crk2 0.0223 0.0749 0.6469
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0126 0.0375 0.0375
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.031 0.2363
Schistosoma mansoni opsin-like receptor 0.0038 0.0037 0.0037
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0229 0.0769 0.0769
Echinococcus multilocularis protein KINase family member (kin 25) 0.0066 0.0143 0.0141
Onchocerca volvulus 0.0066 0.0143 0.0203
Loa Loa (eye worm) protein-tyrosine phosphatase 0.004 0.0042 0.0042
Entamoeba histolytica protein kinase, putative 0.0367 0.1302 1
Trichomonas vaginalis esterase, putative 0.0039 0.0038 0.0172
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.0307 0.0305
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0066 0.0143 0.0143
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0038 0.0255
Echinococcus multilocularis expressed protein 0.0451 0.1626 0.1624
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.004 0.0042 0.004
Echinococcus granulosus retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Schistosoma mansoni suppressor of cytokine signaling 0.004 0.0042 0.0042
Plasmodium falciparum SET domain protein, putative 0.0329 0.1156 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.031 0.069
Echinococcus multilocularis titin 0.0048 0.0075 0.0073
Mycobacterium ulcerans lipase LipD 0.0039 0.0038 0.0047
Loa Loa (eye worm) TK/CSK protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0078 0.0076
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Echinococcus multilocularis roundabout 2 0.0118 0.0343 0.0341
Onchocerca volvulus 0.0038 0.0037 0.0052
Loa Loa (eye worm) hypothetical protein 0.0353 0.125 0.125
Brugia malayi Tyrosine-protein kinase abl-1 0.0128 0.0382 0.0382
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0066 0.0143 0.0143
Toxoplasma gondii thioredoxin reductase 0.0047 0.0072 0.0171
Echinococcus multilocularis NCK adaptor protein 0.0068 0.0153 0.0151
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.001 0.001
Plasmodium falciparum protein kinase 5 0.0223 0.0749 0.6469
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2093 0.7954 0.7954
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni neuroglian 0.0118 0.0343 0.0343
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Dopamine receptor protein 2 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni netrin receptor unc5 0.0068 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.025 0.0854 0.2044
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0047 0.0071 0.0071
Schistosoma mansoni tyrosine kinase 0.025 0.0853 0.0853
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0056 0.0103 0.0103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0092 0.0245 0.0244
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis RUN 0.004 0.0041 0.004
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.025 0.0854 0.2044
Entamoeba histolytica protein kinase, putative 0.0367 0.1302 1
Schistosoma mansoni hypothetical protein 0.004 0.0041 0.0041
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0188 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0033 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Schistosoma mansoni titin 0.0048 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Brugia malayi SH2 domain containing protein 0.0374 0.133 0.133
Echinococcus multilocularis receptor type guanylyl cyclase 0.0066 0.0143 0.0141
Toxoplasma gondii fructose-bisphospatase II 0.1081 0.4056 1
Echinococcus multilocularis 0.004 0.0042 0.004
Schistosoma mansoni protein tyrosine kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Giardia lamblia Kinase 0.0066 0.0143 0.1249
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0003 0.5
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0068 0.015 0.015
Schistosoma mansoni glutaminase 0.0561 0.2052 0.2052
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0209 0.0694 0.0692
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0031 0.001 0.001
Echinococcus multilocularis serotonin receptor 0.0038 0.0037 0.0035
Echinococcus granulosus neuropeptide receptor 0.0038 0.0037 0.0035
Echinococcus multilocularis Immunoglobulin 0.0229 0.0769 0.0768
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.004 0.0042 0.006
Trypanosoma cruzi cdc2-related kinase 1 0.0223 0.0749 0.1782
Schistosoma mansoni tyrosine protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0231 0.0777 0.0777
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0037 0.0037
Plasmodium falciparum protein serine/threonine kinase-1 0.025 0.0854 0.7381
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0066 0.0143 0.0685
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.031 0.1498
Schistosoma mansoni intermediate filament proteins 0.0057 0.0107 0.0107
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0032 0.5
Brugia malayi GnHR receptor homolog 0.0038 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) TK/ACK protein kinase 0.0066 0.0143 0.0143
Echinococcus granulosus titin 0.0048 0.0075 0.0073
Echinococcus multilocularis neuropeptide receptor A26 0.0489 0.1774 0.1772
Echinococcus multilocularis cyclin dependent kinase 1 0.0223 0.0749 0.0747
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0434 0.0434
Schistosoma mansoni septate junction protein 0.0116 0.0335 0.0335
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0037 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.031 0.1498
Brugia malayi cytokine inducible SH2-containing protein 5 0.004 0.0042 0.0042
Echinococcus multilocularis GPCR, family 2 0.0049 0.0078 0.0076
Echinococcus multilocularis dual specificity 0.0367 0.1302 0.13
Echinococcus granulosus RUN 0.004 0.0041 0.004
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0047 0.0071 0.0071
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Brugia malayi hypothetical protein 0.0076 0.0184 0.0184
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0434 0.0432
Schistosoma mansoni vav2 0.0047 0.0071 0.0071
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0074 0.0175 0.0355
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0164 0.052 0.052
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Loa Loa (eye worm) variant SH3 domain-containing protein 0.004 0.0042 0.0042
Echinococcus multilocularis tyrosine kinase 0.0066 0.0143 0.0141
Brugia malayi Protein kinase domain containing protein 0.0873 0.3254 0.3254
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0037 0.0035
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis tyrosine kinase 0.0106 0.0296 0.0294
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.025 0.0853 0.0851
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0066 0.0143 0.0143
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0037 0.0035
Onchocerca volvulus 0.0038 0.0037 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.031 0.031
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0285 0.0285
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0116 0.0115
Brugia malayi Immunoglobulin domain containing protein 0.0068 0.015 0.015
Onchocerca volvulus 0.0039 0.0038 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0196 0.0644 0.0644
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis suppressor of cytokine signaling 7 0.004 0.0042 0.004
Echinococcus granulosus g protein coupled receptor 0.0038 0.0037 0.0035
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Brugia malayi Tyrosine-protein kinase abl-1 0.0214 0.0712 0.0712
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0169 0.0539 0.0539
Brugia malayi Protein kinase domain containing protein 0.0106 0.0296 0.0296
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.031 0.0441
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0196 0.0644 0.0643
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0245 0.0349
Onchocerca volvulus 0.004 0.0042 0.006
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Entamoeba histolytica hypothetical protein 0.0367 0.1302 1
Plasmodium vivax protein kinase, putative 0.007 0.0159 0.136
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0037 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis microsomal glutathione S transferase 3 0.008 0.0198 0.0196
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0037 0.0035
Echinococcus granulosus protein kinase 0.0066 0.0143 0.0141
Brugia malayi putative neuropeptide receptor 0.0038 0.0037 0.0037
Echinococcus granulosus epidermal growth factor receptor 0.1434 0.5413 0.5412
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0038 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0099 0.0469
Echinococcus granulosus tyrosine protein kinase shark 0.0106 0.0296 0.0295
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0035 0.0025 0.0023
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0037 0.0035
Brugia malayi protein-tyrosine kinase 0.0221 0.0742 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0254 0.0254
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0066 0.0143 0.0143
Schistosoma mansoni serine/threonine RGC 0.0066 0.0143 0.0143
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0402 0.1438 0.3496
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.0288 0.0288
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0038 0.0255
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0116 0.0115
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0037 0.0035
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Echinococcus multilocularis microtubule associated protein 2 0.1451 0.5482 0.5481
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0306 0.6073
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0092 0.0245 0.0245
Onchocerca volvulus 0.0033 0.0017 0.0024
Brugia malayi Peroxidasin 0.0116 0.0335 0.0335
Onchocerca volvulus 0.0038 0.0037 0.0052
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0125 0.0124
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0066 0.0143 0.0276
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0072 0.0165 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.001 0.001
Echinococcus granulosus neuroglian 0.0118 0.0343 0.0341
Schistosoma mansoni protein kinase 0.0074 0.0175 0.0175
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0066 0.0143 0.0143
Echinococcus multilocularis beta adrenergic receptor kinase 0.0031 0.001 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0038 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0434 0.0434
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus g protein coupled receptor 0.0038 0.0037 0.0035
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0157 0.0493 0.5788
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0038 0.0038
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.004 0.0042 0.004
Echinococcus granulosus dnaJ subfamily B 0.0411 0.1472 0.147
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0066 0.0143 0.0203
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Brugia malayi Heparan sulfate 0.0068 0.015 0.015
Schistosoma mansoni SH2A 0.004 0.0042 0.0042
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0044 0.0057 0.0134
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.031 0.031
Brugia malayi protein unc-22 0.0058 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0504 0.1829 0.1829
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus multilocularis lamin dm0 0.0057 0.0107 0.0106
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus multilocularis L aminoadipate semialdehyde 0.0047 0.0071 0.0069
Loa Loa (eye worm) serine/threonine protein kinase 0.0066 0.0143 0.0143
Brugia malayi Serotonin receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0048 0.0075 0.0073
Brugia malayi Protein kinase domain containing protein 0.0311 0.1086 0.1086
Onchocerca volvulus 0.0092 0.0245 0.0349
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0076 0.0183 0.0376
Onchocerca volvulus 0.0038 0.0037 0.0052
Schistosoma mansoni hemicentin 0.005 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Plasmodium vivax glutathione reductase, putative 0.0047 0.0072 0.0601
Schistosoma mansoni hypothetical protein 0.0411 0.1472 0.1472
Loa Loa (eye worm) hypothetical protein 0.0151 0.0472 0.0472
Brugia malayi Prion-like- 0.0048 0.0075 0.0075
Trichomonas vaginalis glutaminase, putative 0.0561 0.2052 1
Onchocerca volvulus 0.0038 0.0037 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) LAD-2 short isoform 0.0068 0.015 0.015
Brugia malayi tRNA modification GTPase TrmE family protein 0.004 0.0042 0.0042
Onchocerca volvulus 0.0066 0.0143 0.0203
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Loa Loa (eye worm) nuclear receptor NHR-67 0.0092 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0068 0.015 0.015
Echinococcus multilocularis epidermal growth factor receptor 0.1434 0.5413 0.5412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0037 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0343 0.0343
Giardia lamblia Kinase, NEK 0.0066 0.0143 0.1249
Schistosoma mansoni roundabout 0.0116 0.0335 0.0335
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0066 0.0143 0.0685
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0157 0.0493 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.0307 0.0684
Echinococcus granulosus mitogen activated protein kinase 11 0.0134 0.0406 0.0404
Echinococcus multilocularis tensin 0.004 0.0042 0.004
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0114 0.0329 0.0327
Loa Loa (eye worm) hypothetical protein 0.0229 0.0769 0.0769
Loa Loa (eye worm) hypothetical protein 0.0358 0.127 0.127
Echinococcus multilocularis activated cdc42 kinase 1 0.0066 0.0143 0.0141
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0037 0.0037
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0037 0.0037
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0048 0.0075 0.0073
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0041 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Schistosoma mansoni septate junction protein 0.0068 0.015 0.015
Echinococcus multilocularis tyrosine protein kinase csk 0.0066 0.0143 0.0141
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0032 0.0072
Schistosoma mansoni cell adhesion molecule 0.005 0.0082 0.0082
Schistosoma mansoni eyes absent homolog 0.0086 0.0222 0.0222
Leishmania major 0.1081 0.4056 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0041 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Echinococcus multilocularis N chimaerin 0.0047 0.0071 0.0069
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0048 0.0075 0.0073
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0096 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Plasmodium falciparum tyrosine kinase-like protein 0.0066 0.0143 0.1217
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0134 0.0407 0.0407
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Brugia malayi Protein kinase domain containing protein 0.0106 0.0296 0.0296
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0052 0.0427
Onchocerca volvulus 0.0106 0.0296 0.0421
Loa Loa (eye worm) hypothetical protein 0.0068 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0123 0.0123
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0068 0.015 0.0148
Schistosoma mansoni basigin related 0.0068 0.015 0.015
Echinococcus multilocularis mitogen activated protein kinase 11 0.0134 0.0406 0.0404
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0092 0.0245 0.0244
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0306 0.3515
Plasmodium falciparum protein kinase, putative 0.0074 0.0175 0.1491
Trichomonas vaginalis TK family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0125 0.0233
Schistosoma mansoni basigin related 0.0068 0.015 0.015
Echinococcus multilocularis roundabout 2 0.0118 0.0343 0.0341
Echinococcus granulosus tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Echinococcus multilocularis SH2 motif 0.004 0.0042 0.004
Schistosoma mansoni titin 0.0048 0.0075 0.0075
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0125 0.0125
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0215 0.0717 0.0717
Mycobacterium tuberculosis Conserved protein 0.0039 0.0038 0.0255
Schistosoma mansoni thyroid hormone receptor 0.0196 0.0644 0.0644
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0057 0.0057
Echinococcus granulosus bloom syndrome protein 0.0048 0.0074 0.0072
Onchocerca volvulus 0.0048 0.0075 0.0106
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0245 0.0349
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus granulosus leucine rich repeat containing protein 4 0.0048 0.0075 0.0073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0038 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Trypanosoma brucei protein kinase, putative 0.0108 0.0307 0.0684
Giardia lamblia Kinase, PLK 0.0109 0.031 0.2735
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.025 0.0853 0.0851
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Schistosoma mansoni hypothetical protein 0.0038 0.0037 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Echinococcus multilocularis 0.0048 0.0075 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0099 0.0469
Schistosoma mansoni caspase-7 (C14 family) 0.0041 0.0047 0.0047
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni signal transduction protein lnk-related 0.004 0.0042 0.0042
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0038 0.0255
Echinococcus multilocularis growth factor receptor bound protein 2 0.0068 0.0153 0.0151
Schistosoma mansoni amine GPCR 0.0038 0.0037 0.0037
Schistosoma mansoni cpg binding protein 0.003 0.0006 0.0006
Treponema pallidum fructose-bisphosphate aldolase 0.0321 0.1126 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0037 0.0037
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0116 0.0335 0.0335
Echinococcus granulosus neuroglian 0.0277 0.0955 0.0953
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.008 0.0198 0.0198
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Brugia malayi nuclear receptor RXR 0.0092 0.0245 0.0245
Brugia malayi SH2 domain containing protein 0.0106 0.0296 0.0296
Loa Loa (eye worm) raf kinase 0.0217 0.0723 0.0723
Schistosoma mansoni neuropeptide receptor 0.0038 0.0037 0.0037
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.007 0.0159 0.0762
Loa Loa (eye worm) hypothetical protein 0.0155 0.0486 0.0486
Schistosoma mansoni inositol monophosphatase 0.0037 0.0032 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Echinococcus granulosus contactin 0.0127 0.0377 0.0375
Onchocerca volvulus 0.0106 0.0296 0.0421
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Brugia malayi hypothetical protein 0.0231 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Brugia malayi 6-phosphofructokinase 0.0109 0.031 0.031
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0037 0.0035
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis titin 0.0048 0.0075 0.0073
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.0307 0.0751
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0037 0.0035
Echinococcus granulosus lamin 0.0057 0.0107 0.0106
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0035 0.0025 0.0025
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0037 0.0035
Brugia malayi integrin-linked kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0037 0.0035
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0223 0.0749 0.1782
Trypanosoma brucei cAMP-specific phosphodiesterase 0.007 0.0159 0.0315
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0125 0.1319
Schistosoma mansoni steroid hormone receptor ad4bp 0.0196 0.0644 0.0644
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Echinococcus granulosus roundabout 2 0.0346 0.1224 0.1222
Loa Loa (eye worm) hypothetical protein 0.0041 0.0047 0.0047
Brugia malayi jmjC domain containing protein 0.0059 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Echinococcus multilocularis signal transduction protein lnk realted 0.004 0.0042 0.004
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0037 0.0037
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0068 0.015 0.015
Plasmodium vivax tyrosine kinase-like protein, putative 0.0066 0.0143 0.1217
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.025 0.0854 0.2044
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0037 0.0035
Echinococcus multilocularis integrin linked protein kinase 0.0066 0.0143 0.0141
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0032 0.0225
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi nuclear hormone receptor family member odr-7 0.0092 0.0245 0.0245
Trypanosoma brucei trypanothione reductase 0.0047 0.0072 0.01
Echinococcus granulosus fructose 16 bisphosphatase 1 0.1081 0.4056 0.4054
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0066 0.0143 0.0143
Onchocerca volvulus 0.0044 0.0057 0.0081
Leishmania major trypanothione reductase 0.0047 0.0072 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Echinococcus granulosus NCK adaptor protein 0.0068 0.0153 0.0151
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0229 0.0769 0.0769
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0196 0.0644 0.0644
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis DNA helicase recq1, putative 0.0048 0.0074 0.035
Echinococcus granulosus dual specificity protein kinase clk2 0.025 0.0854 0.0852
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0035 0.0025 0.0025
Echinococcus granulosus hypothetical protein 0.0242 0.0822 0.0821
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0037 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0037 0.0035
Echinococcus granulosus hypothetical protein 0.0038 0.0037 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0037 0.0037
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0038 0.0038
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0174 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0066 0.0143 0.0141
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0076 0.0183 0.0376
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Brugia malayi Protein kinase domain containing protein 0.0367 0.1302 0.1302
Onchocerca volvulus Bile acid receptor homolog 0.0196 0.0644 0.0916
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0174 0.0559 0.0557
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0875 0.3262 0.3261
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0196 0.0644 0.0643
Echinococcus granulosus lamin dm0 0.0057 0.0107 0.0106
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0313 0.1094 0.1093
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0037 0.0037
Entamoeba histolytica receptor protein kinase, putative 0.0066 0.0143 0.108
Mycobacterium ulcerans glutaminase 0.0561 0.2052 1
Onchocerca volvulus 0.004 0.0041 0.0059
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0038 0.0255
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.031 0.139
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0066 0.0143 0.0141
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0037 0.0035
Echinococcus multilocularis nuclear receptor nhr 48 0.0092 0.0245 0.0244
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0035 0.0025 0.0023
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0072 0.0072
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0066 0.0143 0.0141
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis down syndrome cell adhesion 0.0048 0.0075 0.0073
Echinococcus multilocularis epidermal growth factor receptor 0.2624 1 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.005 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0145 0.0448 0.0448
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0306 0.3515
Brugia malayi Animal haem peroxidase family protein 0.0048 0.0075 0.0075
Trypanosoma brucei protein kinase, putative 0.0074 0.0175 0.0355
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0013 0.0025
Onchocerca volvulus 0.0038 0.0037 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0037 0.0035
Onchocerca volvulus 0.0039 0.0038 0.0054
Echinococcus multilocularis tyrosine protein kinase Srms 0.0221 0.0742 0.074
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Echinococcus granulosus insulin receptor 0.0873 0.3254 0.3253
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0082 0.0126
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0343 0.0343
Plasmodium falciparum protein kinase, putative 0.0066 0.0143 0.1217
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0121 0.0356 0.0354
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.031 0.2732
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0092 0.0245 0.0244
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis SHC transforming protein 3 0.004 0.0042 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.031 0.0308
Loa Loa (eye worm) CMGC/CLK protein kinase 0.025 0.0854 0.0854
Echinococcus multilocularis insulin growth factor binding 0.0048 0.0075 0.0073
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0075 0.0075
Brugia malayi Prion-like- 0.0116 0.0335 0.0335
Brugia malayi Dopamine receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) DR-78 0.0092 0.0245 0.0245
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0434 0.0432
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0245 0.0244
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0104 0.0288 0.0288
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0048 0.0075 0.0073
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Entamoeba histolytica tyrosin kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) SH2 domain-containing protein 0.004 0.0042 0.0042
Toxoplasma gondii STE kinase 0.0066 0.0143 0.0346
Echinococcus multilocularis cyclin dependent kinase 5 0.0223 0.0749 0.0747
Brugia malayi hypoxia-induced factor 1 0.0151 0.0472 0.0472
Echinococcus granulosus growth factor receptor bound protein 2 0.0068 0.0153 0.0151
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.0307 0.0684
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) hypothetical protein 0.004 0.0041 0.0041
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0025 0.011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0038 0.0172
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Brugia malayi P38 map kinase family protein 2 0.0134 0.0406 0.0406
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus multilocularis tyrosine protein kinase csk 0.0066 0.0143 0.0141
Echinococcus granulosus activated cdc42 kinase 1 0.0066 0.0143 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Brugia malayi hypothetical protein 0.0106 0.0296 0.0296
Brugia malayi hypothetical protein 0.0495 0.1795 0.1795
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis heat shock protein 70 0.0066 0.0143 0.0141
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0134 0.0406 0.0406
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Brugia malayi 6-phosphofructokinase 0.0109 0.031 0.031
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0183 0.1564
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Entamoeba histolytica protein kinase, putative 0.0048 0.0074 0.0546
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0037 0.0037
Echinococcus granulosus nephrin 0.005 0.0082 0.0081
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0196 0.0644 0.0644
Schistosoma mansoni blooms syndrome DNA helicase 0.0038 0.0035 0.0035
Echinococcus granulosus retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Echinococcus granulosus SH2 domain containing protein 7 0.004 0.0042 0.004
Echinococcus granulosus tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.031 0.031
Schistosoma mansoni lipoxygenase 0.0174 0.0559 0.0559
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0037 0.0037
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Onchocerca volvulus 0.0106 0.0296 0.0421
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0125 0.0124
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.004 0.0042 0.0042
Schistosoma mansoni biogenic amine receptor 0.0038 0.0037 0.0037
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0032 0.0143
Brugia malayi Immunoglobulin domain containing protein 0.0068 0.015 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0037 0.0035
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis Immunoglobulin 0.0068 0.015 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Brugia malayi hypothetical protein 0.004 0.0041 0.0041
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis neuroglian 0.0277 0.0955 0.0953
Echinococcus granulosus roundabout 2 0.0118 0.0343 0.0341
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0749 0.3642
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0245 0.0245
Schistosoma mansoni thyroid hormone receptor 0.0196 0.0644 0.0644
Loa Loa (eye worm) CAMK protein kinase 0.0058 0.0114 0.0114
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0038 0.0036
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0075 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0038 0.0015
Echinococcus granulosus hemicentin 1 0.0125 0.0369 0.0367
Echinococcus multilocularis tyrosine protein kinase csk 0.0066 0.0143 0.0141
Entamoeba histolytica cell division protein kinase 2, putative 0.0223 0.0749 0.5743
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0104 0.0288 0.0288
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0078 0.0078
Giardia lamblia Kinase, CMGC CDK 0.0223 0.0749 0.664
Onchocerca volvulus 0.0057 0.0107 0.0153
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.007 0.0159 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0114 0.0114
Brugia malayi basement membrane proteoglycan 0.0068 0.015 0.015
Brugia malayi PAS domain containing protein 0.0049 0.0077 0.0077
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.007 0.0159 0.0315
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0037 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0125 0.0481
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0066 0.0143 0.0141
Schistosoma mansoni lamin 0.0057 0.0107 0.0107
Brugia malayi photoreceptor-specific nuclear receptor 0.0196 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) glutathione reductase 0.0047 0.0072 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.058 0.2818
Schistosoma mansoni cell adhesion molecule 0.005 0.0082 0.0082
Echinococcus multilocularis protein kinase 0.0066 0.0143 0.0141
Schistosoma mansoni titin 0.0048 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0078
Echinococcus granulosus Immunoglobulin 0.0068 0.015 0.0148
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0041 0.0338
Echinococcus granulosus low density lipoprotein receptor ldl 0.0068 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni cell adhesion molecule 0.0068 0.015 0.015
Echinococcus multilocularis caspase 2 0.0041 0.0047 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0307 0.1485
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0545 0.0774
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Schistosoma mansoni GTPase activating protein 0.004 0.0042 0.0042
Schistosoma mansoni cell adhesion molecule 0.0118 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0231 0.0777 0.0777
Brugia malayi fructose-1,6-bisphosphatase 0.1081 0.4056 0.4056
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0086 0.0222 0.0222
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.0307 0.0684
Trypanosoma cruzi cdc2-related kinase 3 0.0223 0.0749 0.1782
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0066 0.0143 0.0143
Leishmania major protein kinase, putative 0.025 0.0854 0.2044
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0307 0.0684
Leishmania major hypothetical protein, conserved 0.0039 0.0038 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Brugia malayi steroid hormone receptor 0.0196 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0104 0.0288 0.0288
Echinococcus granulosus tyrosine kinase 0.0106 0.0296 0.0294
Echinococcus multilocularis netrin receptor unc 5 0.0082 0.0205 0.0204
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0245 0.0244
Echinococcus multilocularis protein kinase 0.0066 0.0143 0.0141
Brugia malayi larval opioid receptor 0.0038 0.0037 0.0037
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0164 0.0522 0.052
Onchocerca volvulus 0.0038 0.0037 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) hypothetical protein 0.0495 0.1795 0.1795
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.0307 0.0305
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0196 0.0644 0.0643
Entamoeba histolytica serine/threonine kinase, putative 0.0066 0.0143 0.108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Trypanosoma cruzi cdc2-related kinase 3 0.0223 0.0749 0.1782
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0434 0.0432
Trypanosoma brucei Pseudokinase, putative 0.0066 0.0143 0.0276
Echinococcus multilocularis insulin receptor 0.0873 0.3254 0.3253
Brugia malayi ecdysone receptor 0.0092 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2621 0.999 0.999
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0048 0.0075 0.0075
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0037 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0125 0.0481
Onchocerca volvulus 0.0106 0.0296 0.0421
Brugia malayi phosphofructokinase 0.0109 0.031 0.031
Brugia malayi Cytochrome P450 family protein 0.0034 0.0022 0.0022
Schistosoma mansoni nck2/grb4 0.0068 0.0153 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0196 0.0644 0.0644
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0074 0.0175 0.0355
Loa Loa (eye worm) hypothetical protein 0.0049 0.0078 0.0078
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0116 0.0335 0.0335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0196 0.0644 0.0644
Brugia malayi Protein-tyrosine phosphatase containing protein 0.004 0.0042 0.0042
Onchocerca volvulus Tyrosine kinase homolog 0.1854 0.7032 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0307 0.0684
Loa Loa (eye worm) doublecortin family protein 0.004 0.0041 0.0041
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0245 0.0244
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.005 0.0082 0.0081
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.004 0.0042 0.004
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.025 0.0854 0.2044
Toxoplasma gondii hypothetical protein 0.0054 0.0099 0.0237
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0037 0.0035
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0066 0.0143 0.0141
Brugia malayi MH2 domain containing protein 0.012 0.0351 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0196 0.0644 0.0644
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0037 0.0037
Plasmodium vivax tyrosine kinase-like protein, putative 0.0066 0.0143 0.1217
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0047 0.0071 0.0071
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0066 0.0143 0.0143
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0367 0.1302 0.3156
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Echinococcus granulosus cyclin dependent kinase 1 0.0223 0.0749 0.0747
Echinococcus multilocularis 0.0796 0.2957 0.2956
Echinococcus granulosus Immunoglobulin 0.0068 0.015 0.0148
Brugia malayi glutaminase DH11.1 0.0561 0.2052 0.2052
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0077 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0068 0.015 0.0148
Entamoeba histolytica cysteine surface protein, putative 0.0066 0.0143 0.108
Leishmania major protein kinase, putative 0.0066 0.0143 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0196 0.0644 0.0644
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Brugia malayi RE15519p 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus tyrosine protein kinase csk 0.0066 0.0143 0.0141
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0038 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0888 0.0888
Toxoplasma gondii histone lysine methyltransferase SET8 0.0329 0.1156 0.2846
Giardia lamblia Kinase, NEK 0.0066 0.0143 0.1253
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0037 0.0035
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0037 0.0035
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Brugia malayi Receptor family ligand binding region containing protein 0.0066 0.0143 0.0143
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) one IG domain family member 0.0048 0.0075 0.0075
Echinococcus granulosus neuropeptide receptor 0.0038 0.0037 0.0035
Echinococcus granulosus activated cdc42 kinase 1 0.0066 0.0143 0.0141
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0343 0.0343
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0058 0.0114 0.0114
Brugia malayi glutathione reductase 0.0047 0.0072 0.0072
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0066 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0068 0.015 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus tyrosine protein kinase pr2 0.0066 0.0143 0.0141
Echinococcus granulosus ephrin type A receptor 4 A 0.0133 0.0403 0.0401
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.031 0.0691
Loa Loa (eye worm) hypothetical protein 0.0229 0.0769 0.0769
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.084 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0196 0.0644 0.0643
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0223 0.0749 0.0749
Brugia malayi Bloom's syndrome protein homolog 0.0048 0.0074 0.0074
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Brugia malayi hypothetical protein 0.0066 0.0143 0.0143
Echinococcus granulosus tyrosine protein kinase 0.0066 0.0143 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0107 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi AKH receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.0486 0.0486
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0037 0.0035
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0066 0.0143 0.0346
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Echinococcus granulosus Immunoglobulin subtype 0.0068 0.015 0.0148
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0223 0.0749 0.1841
Echinococcus granulosus neuropeptide s receptor 0.0489 0.1774 0.1772
Schistosoma mansoni hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0143 0.0685
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0078 0.0078
Echinococcus multilocularis Immunoglobulin subtype 0.0068 0.015 0.0148
Schistosoma mansoni tyrosine kinase 0.0273 0.0941 0.0941
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0353 0.4081
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus granulosus tyrosine protein kinase Srms 0.0106 0.0296 0.0294
Loa Loa (eye worm) hypothetical protein 0.0104 0.0288 0.0288
Echinococcus multilocularis hemicentin 1 0.0116 0.0335 0.0334
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0329 0.1156 0.1155
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0078 0.0078
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0047 0.0071 0.0069
Onchocerca volvulus 0.004 0.0042 0.006
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0037 0.0037
Echinococcus granulosus FTZ F1 alpha 0.0196 0.0644 0.0643
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0106 0.0296 0.0294
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0086 0.0222 0.0222
Echinococcus multilocularis tyrosine protein kinase pr2 0.0066 0.0143 0.0141
Onchocerca volvulus 0.0059 0.0116 0.0165
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0116 0.0335 0.0335
Echinococcus granulosus tensin C1 domain containing phosphatase 0.004 0.0042 0.004
Giardia lamblia Kinase, CMGC CDK 0.0223 0.0749 0.664
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Entamoeba histolytica protein kinase, putative 0.0182 0.0589 0.4512
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.005 0.0082 0.0082
Schistosoma mansoni growth factor receptor-bound protein 0.0068 0.0153 0.0153
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0037 0.0035
Trypanosoma brucei Flagellum attachment zone protein 20 0.0066 0.0143 0.0276
Onchocerca volvulus 0.0196 0.0644 0.0916
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0118 0.0343 0.0341
Entamoeba histolytica ankyrin repeat protein 0.0066 0.0143 0.108
Entamoeba histolytica tyrosin kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis transfer RNA-Phe 0.005 0.0082 0.0081
Toxoplasma gondii fructose-bisphospatase I 0.0402 0.1438 0.3543
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0134 0.0406 0.093
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0123 0.0123
Brugia malayi Raf kinase 0.0275 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus multilocularis tyrosine protein kinase Src64B 0.025 0.0853 0.0851
Schistosoma mansoni fructose-16-bisphosphatase-related 0.1081 0.4056 0.4056
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.031 0.3554
Echinococcus multilocularis peroxidasin 0.0116 0.0335 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.1033 0.387 0.3869
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.0307 0.0305
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0074 0.0175 0.0175
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0196 0.0644 0.0644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.0196 0.0644 0.0644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0074 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0106 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0066 0.0143 0.0141
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0221 0.0742 0.074
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0025 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0196 0.0644 0.0644
Echinococcus granulosus defective proboscis extension response 0.0229 0.0769 0.0768
Schistosoma mansoni tyrosine kinase 0.2624 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0223 0.0749 0.0747
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.0307 0.0307
Echinococcus granulosus expressed conserved protein 0.004 0.0042 0.004
Echinococcus multilocularis mitogen activated protein kinase 11 0.0134 0.0406 0.0404
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0196 0.0644 0.0644
Onchocerca volvulus 0.0066 0.0143 0.0203
Schistosoma mansoni nuclear receptor 0.0092 0.0245 0.0245
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0321 0.1126 0.865
Brugia malayi hypothetical protein 0.0092 0.0245 0.0245
Onchocerca volvulus 0.0038 0.0037 0.0052
Echinococcus granulosus tyrosine protein kinase ABL1 0.0313 0.1094 0.1093
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0068 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Loa Loa (eye worm) TK protein kinase 0.0182 0.0589 0.0589
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0037 0.0037
Brugia malayi Guanylyl cyclase protein 23 0.0066 0.0143 0.0143
Echinococcus granulosus receptor type guanylyl cyclase 0.0066 0.0143 0.0141
Schistosoma mansoni cell adhesion molecule 0.0118 0.0343 0.0343
Schistosoma mansoni cpg binding protein 0.003 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0047 0.0071 0.0071
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Echinococcus granulosus geminin 0.034 0.1198 0.1196
Schistosoma mansoni opsin-like receptor 0.0038 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0143 0.0143
Echinococcus granulosus insulin growth factor binding 0.0048 0.0075 0.0073
Brugia malayi G-protein coupled receptor 0.0038 0.0037 0.0037
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0033 0.0017 0.0017
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0038 0.0037 0.0052
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0038 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0854 0.0854
Schistosoma mansoni neuropeptide receptor 0.0038 0.0037 0.0037
Brugia malayi Melatonin receptor type 1A 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0374 0.133 0.133
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0038 0.0037 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0854 0.0854
Brugia malayi Thrombospondin type 1 domain containing protein 0.0072 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus microtubule associated protein 2 0.1451 0.5482 0.5481
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0068 0.015 0.015
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.025 0.0854 0.2101
Loa Loa (eye worm) TK/ROR protein kinase 0.0114 0.0329 0.0329
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi hypothetical protein 0.004 0.0042 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0231 0.0777 0.0777
Schistosoma mansoni lamin 0.0057 0.0107 0.0107
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0068 0.015 0.015
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0402 0.1438 0.3543
Brugia malayi Immunoglobulin I-set domain containing protein 0.2093 0.7954 0.7954
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0035 0.0025 0.0025
Brugia malayi hypothetical protein 0.0504 0.1829 0.1829
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0171 0.0171
Schistosoma mansoni tyrosine kinase 0.1434 0.5413 0.5413
Loa Loa (eye worm) hypothetical protein 0.0242 0.0822 0.0822
Schistosoma mansoni single-minded 0.0049 0.0077 0.0077
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0033 0.0017 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0196 0.0644 0.0644
Echinococcus multilocularis tyrosine protein kinase Fgr 0.025 0.0853 0.0851
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0072 0.01
Echinococcus granulosus integrin linked protein kinase 0.0066 0.0143 0.0141
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.031 0.069
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.025 0.0853 0.0851
Onchocerca volvulus 0.0066 0.0143 0.0203
Giardia lamblia Kinase, CMGC CLK 0.025 0.0854 0.7577
Onchocerca volvulus 0.0038 0.0037 0.0052
Echinococcus multilocularis SH2 domain containing protein 7 0.004 0.0042 0.004
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Onchocerca volvulus 0.004 0.0041 0.0059
Brugia malayi nuclear receptor RXR 0.0104 0.0288 0.0288
Echinococcus granulosus caspase 2 0.0041 0.0047 0.0045
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0125 0.0369 0.0525
Brugia malayi Protein kinase domain containing protein 0.0223 0.0749 0.0749
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0057 0.0055
Schistosoma mansoni amine GPCR 0.0038 0.0037 0.0037
Trypanosoma cruzi protein kinase, putative 0.0066 0.0143 0.0276
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0076 0.0183 0.0376
Echinococcus granulosus twitchin 0.0285 0.0987 0.0985
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Echinococcus granulosus expressed protein 0.0451 0.1626 0.1624
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) projectin 0.005 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0037 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0196 0.0644 0.0643
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0164 0.0522 0.052
Entamoeba histolytica hypothetical protein, conserved 0.0066 0.0143 0.108
Brugia malayi nuclear receptor NHR-67 0.0092 0.0245 0.0245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0037 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0209 0.0694 0.0694
Mycobacterium ulcerans beta-lactamase 0.0039 0.0038 0.0047
Brugia malayi ecdysteroid receptor 0.0196 0.0644 0.0644
Brugia malayi kettin 0.0048 0.0075 0.0075
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0423 0.152 0.152
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0814 0.3027 0.3026
Schistosoma mansoni growth factor receptor-bound protein 0.0068 0.0153 0.0153
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0038 0.044
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Entamoeba histolytica protein kinase domain containing protein 0.0367 0.1302 1
Plasmodium falciparum protein kinase, putative 0.0066 0.0143 0.1217
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0209 0.0694 0.0694
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trypanosoma cruzi cdc2-related kinase 1 0.0223 0.0749 0.1782
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0358 0.127 0.127
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0245 0.0245
Onchocerca volvulus 0.0048 0.0075 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0749 0.3642
Echinococcus multilocularis hemicentin 1 0.0125 0.0369 0.0367
Echinococcus granulosus L aminoadipate semialdehyde 0.0047 0.0071 0.0069
Loa Loa (eye worm) RecQ helicase 0.0048 0.0074 0.0074
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis STE family protein kinase 0.0066 0.0143 0.0685
Brugia malayi nuclear receptor NHR-88 0.0092 0.0245 0.0245
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Leishmania major protein kinase, putative 0.025 0.0854 0.2044
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.004 0.0042 0.006
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0092 0.0245 0.0244
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0037 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0434 0.0434
Mycobacterium ulcerans hypothetical protein 0.0039 0.0038 0.0047
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0066 0.0143 0.0143
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0367 0.1302 0.3156
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0033 0.0017 0.0017
Onchocerca volvulus 0.004 0.0042 0.006
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0032 0.003
Onchocerca volvulus 0.0038 0.0037 0.0052
Brugia malayi Prion-like- 0.0048 0.0075 0.0075
Echinococcus multilocularis ecdysone induced protein 78C 0.0196 0.0644 0.0643
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.031 0.2366
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0196 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0033 0.0017 0.0017
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1434 0.5413 0.5412
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Schistosoma mansoni septate junction protein 0.0116 0.0335 0.0335
Onchocerca volvulus 0.0266 0.0914 0.1299
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0245 0.0245
Schistosoma mansoni nuclear receptor nhr-48 0.0092 0.0245 0.0245
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0155 0.0488 0.0486
Schistosoma mansoni nephrin related 0.0048 0.0075 0.0075
Schistosoma mansoni rab6-interacting 0.004 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0196 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni tensin-related 0.004 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0066 0.0143 0.108
Echinococcus granulosus cpg binding protein 0.003 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0033 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0041 0.0047 0.0047
Brugia malayi nuclear hormone receptor 0.0196 0.0644 0.0644
Schistosoma mansoni tyrosine-protein kinase zap-70 0.004 0.0042 0.0042
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0037 0.0037
Brugia malayi nuclear hormone receptor 0.0092 0.0245 0.0245
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus granulosus sex peptide receptor 0.0038 0.0037 0.0035
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0125 0.0125
Brugia malayi nuclear hormone receptor family member nhr-6 0.0092 0.0245 0.0245
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0066 0.0143 0.0141
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.005 0.0082 0.039
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Loa Loa (eye worm) glutaminase 0.0561 0.2052 0.2052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0196 0.0644 0.0644
Onchocerca volvulus 0.0047 0.0071 0.01
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0047 0.0071 0.0071
Trichomonas vaginalis DNA helicase recq, putative 0.0048 0.0074 0.035
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus multilocularis Immunoglobulin 0.0229 0.0769 0.0768
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0078
Brugia malayi SH2 domain containing protein 0.0106 0.0296 0.0296
Brugia malayi orphan nuclear receptor NR2E1 0.0092 0.0245 0.0245
Schistosoma mansoni tensin-related 0.004 0.0042 0.0042
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0003 0.5
Leishmania major hypothetical protein, conserved 0.0066 0.0143 0.0276
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.0307 0.2708
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.025 0.0853 0.0851
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0306 0.3515
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0134 0.0406 0.093
Schistosoma mansoni nephrin related 0.0068 0.015 0.015
Brugia malayi hypothetical protein 0.0104 0.0288 0.0288
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0066 0.0143 0.0203
Trypanosoma brucei cdc2-related kinase 3 0.0223 0.0749 0.1782
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0038 0.0255
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Toxoplasma gondii MAPEG family protein 0.008 0.0198 0.0483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Echinococcus multilocularis tyrosine protein kinase HCK 0.0182 0.0589 0.0587
Brugia malayi G-protein coupled receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis expressed conserved protein 0.0081 0.0203 0.0201
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) TK/Met protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus granulosus tyrosine protein kinase csk 0.0066 0.0143 0.0141
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0066 0.0143 0.108
Echinococcus granulosus lachesin 0.0116 0.0335 0.0334
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0068 0.015 0.0148
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0092 0.0245 0.0245
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0106 0.0296 0.2258
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0229 0.0769 0.0768
Echinococcus granulosus natriuretic peptide receptor 1 0.0066 0.0143 0.0141
Onchocerca volvulus 0.004 0.0042 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0307 0.0307
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase HCK 0.0182 0.0589 0.0587
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0402 0.1438 0.3496
Loa Loa (eye worm) phosphofructokinase 0.0109 0.031 0.031
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0037 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus granulosus kinase suppressor of Ras 1 0.0066 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis SH2 domain containing adapter protein F 0.004 0.0042 0.004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0196 0.0644 0.0643
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0196 0.0644 0.0916
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus granulosus titin 0.0058 0.0114 0.0112
Brugia malayi Protein kinase domain containing protein 0.0106 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0066 0.0143 0.0143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.031 0.031
Giardia lamblia Protein 21.1 0.0066 0.0143 0.1249
Brugia malayi Cell death protein 3 precursor 0.0041 0.0047 0.0047
Loa Loa (eye worm) TK/DDR protein kinase 0.0066 0.0143 0.0143
Echinococcus granulosus cyclin dependent kinase 5 0.0223 0.0749 0.0747
Schistosoma mansoni tyrosine kinase 0.0873 0.3254 0.3254
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0153 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus multilocularis lachesin 0.0116 0.0335 0.0334
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Protein kinase domain containing protein 0.0106 0.0296 0.0296
Brugia malayi beta-lactamase 0.0039 0.0038 0.0038
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0209 0.0694 0.0692
Brugia malayi RhoGAP domain containing protein 0.0047 0.0071 0.0071
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0076 0.0183 0.0445
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni biogenic amine receptor 0.0038 0.0037 0.0037
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0223 0.0749 0.0749
Echinococcus granulosus basement membrane specific heparan sulfate 0.0068 0.015 0.0148
Onchocerca volvulus 0.004 0.0042 0.006
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0072 0.0601
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0038 0.0047
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0116 0.0115
Entamoeba histolytica SH2 domain containing protein 0.004 0.0042 0.0303
Brugia malayi hypothetical protein 0.0092 0.0245 0.0245
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0146 0.0355
Echinococcus multilocularis tyrosine protein kinase Blk 0.0221 0.0742 0.074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Echinococcus multilocularis mitogen activated protein kinase 14 0.0134 0.0406 0.0404
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0092 0.0245 0.0244
Echinococcus multilocularis titin 0.0048 0.0075 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Echinococcus granulosus Down syndrome cell adhesion molecule 0.007 0.0158 0.0156
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0196 0.0644 0.0643
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Brugia malayi intermediate filament protein 0.0057 0.0107 0.0107
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0092 0.0245 0.0245
Echinococcus granulosus tyrosine protein kinase Src64B 0.025 0.0853 0.0851
Onchocerca volvulus Netrin receptor homolog 0.0071 0.0164 0.0233
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Echinococcus multilocularis c src tyrosine kinase 0.0134 0.0407 0.0405
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) TK/INSR protein kinase 0.0873 0.3254 0.3254
Loa Loa (eye worm) animal heme peroxidase 0.0048 0.0075 0.0075
Brugia malayi Protein kinase domain containing protein 0.025 0.0854 0.0854
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.031 0.2363
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0068 0.015 0.0148
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0351 0.0351
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0329 0.1156 0.1155
Entamoeba histolytica tyrosin kinase, putative 0.0066 0.0143 0.108
Toxoplasma gondii protein kinase 0.0066 0.0143 0.0346
Onchocerca volvulus 0.0066 0.0143 0.0203
Echinococcus granulosus roundabout 2 0.0118 0.0343 0.0341
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0006 0.0006
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0048 0.0075 0.0073
Schistosoma mansoni tensin 0.004 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.1368 0.5159 0.5159
Loa Loa (eye worm) hypothetical protein 0.0229 0.0769 0.0769
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0118 0.0343 0.0341
Onchocerca volvulus 0.0058 0.0114 0.0162
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0888 0.0888
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Schistosoma mansoni hypothetical protein 0.0072 0.0165 0.0165
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Echinococcus granulosus serotonin receptor 0.0038 0.0037 0.0035
Echinococcus granulosus Immunoglobulin 0.0229 0.0769 0.0768
Echinococcus multilocularis suppressor of cytokine signaling 7 0.004 0.0042 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0092 0.0245 0.0244
Echinococcus multilocularis musashi 0.0057 0.0107 0.0106
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0078 0.0076
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0037 0.0037
Echinococcus multilocularis 0.0242 0.0822 0.0821
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0196 0.0644 0.0644
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Schistosoma mansoni amine GPCR 0.0038 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0196 0.0644 0.0644
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Brugia malayi STAT protein, DNA binding domain containing protein 0.004 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Brugia malayi Doublecortin family protein 0.004 0.0041 0.0041
Schistosoma mansoni tyrosine kinase 0.0106 0.0296 0.0296
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0068 0.0153 0.0153
Brugia malayi Tensin 0.004 0.0042 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0307 0.1485
Schistosoma mansoni microtubule-associated protein tau 0.1451 0.5482 0.5482
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0038 0.0037 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis ephrin type A receptor 4 A 0.0133 0.0403 0.0401
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0037 0.0037
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.007 0.0158 0.0158
Brugia malayi G protein-coupled receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0037 0.0035
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0038 0.0172
Mycobacterium tuberculosis Conserved protein 0.0039 0.0038 0.0255
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.005 0.0082 0.0082
Echinococcus granulosus somatostatin receptor 0.0038 0.0037 0.0035
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0296 0.103 0.103
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0066 0.0143 0.0685
Loa Loa (eye worm) hypothetical protein 0.0118 0.0343 0.0343
Brugia malayi Disorganized muscle protein 1 0.0048 0.0075 0.0075
Schistosoma mansoni myosin xvIII 0.0038 0.0037 0.0037
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0367 0.1302 0.3156
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0196 0.0644 0.0644
Trichomonas vaginalis CMGC family protein kinase 0.025 0.0854 0.4156
Onchocerca volvulus 0.0054 0.0099 0.014
Onchocerca volvulus Putative titin 0.0057 0.0108 0.0154
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0042
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Brugia malayi cell division control protein 2 homolog 0.0223 0.0749 0.0749
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0103 0.0285 0.0285
Schistosoma mansoni hypothetical protein 0.0106 0.0297 0.0297
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0329 0.1156 0.1156
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0072 0.007
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0223 0.0749 0.1782
Onchocerca volvulus Cell death protein 3 homolog 0.0041 0.0047 0.0067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0343 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.0196 0.0644 0.0644
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.007 0.0159 0.0159
Schistosoma mansoni histamine h1 receptor 0.0038 0.0037 0.0037
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0006 0.0006
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0367 0.1302 0.1302
Schistosoma mansoni shc transforming protein 0.004 0.0042 0.0042
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0031 0.001 0.001
Toxoplasma gondii protein kinase domain-containing protein 0.0066 0.0143 0.0346
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0047 0.0071 0.0071
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0066 0.0143 0.0143
Onchocerca volvulus 0.0038 0.0037 0.0052
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0048 0.0075 0.0075
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0068 0.0153 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0367 0.1302 0.3156
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase csk 0.0066 0.0143 0.0141
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0157 0.0493 0.2299
Brugia malayi hypothetical protein 0.004 0.0041 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0037 0.0035
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0072 0.007
Entamoeba histolytica protein kinase domain containing protein 0.0074 0.0175 0.1324
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0353 0.4081
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0306 0.3515
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.0288 0.0288
Echinococcus granulosus epidermal growth factor receptor 0.2624 1 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0041 0.0041
Schistosoma mansoni adapter molecule crk 0.0068 0.0153 0.0153
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0037 0.0035
Schistosoma mansoni vesicular amine transporter 0.0229 0.0769 0.0769
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Echinococcus granulosus expressed conserved protein 0.0081 0.0203 0.0201
Loa Loa (eye worm) TK/ABL protein kinase 0.0313 0.1094 0.1094
Entamoeba histolytica ankyrin repeat protein 0.0066 0.0143 0.108
Onchocerca volvulus 0.0038 0.0037 0.0052
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.031 0.0308
Onchocerca volvulus 0.004 0.0042 0.006
Schistosoma mansoni titin 0.0125 0.0369 0.0369
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0196 0.0644 0.0643
Echinococcus multilocularis titin 0.0058 0.0114 0.0112
Brugia malayi hypothetical protein 0.0041 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0402 0.1438 0.3496
Schistosoma mansoni myosin-binding protein-related 0.005 0.0082 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0074 0.0175 0.0173
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.031 0.031
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis tensin 0.004 0.0042 0.004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0307 0.1485
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0078 0.0076
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0196 0.0644 0.0644
Onchocerca volvulus 0.0036 0.0028 0.004
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0223 0.0749 0.0747
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0099 0.0469
Schistosoma mansoni neuropeptide receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis mitogen activated protein kinase 14 0.0134 0.0406 0.0404
Echinococcus granulosus ecdysone induced protein 78C 0.0196 0.0644 0.0643
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0158 0.0158
Brugia malayi Leucine Rich Repeat family protein 0.0048 0.0075 0.0075
Onchocerca volvulus 0.0048 0.0075 0.0106
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0118 0.0343 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.015 0.015
Brugia malayi Protein kinase domain containing protein 0.0423 0.152 0.152
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0076 0.0183 0.0376
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0066 0.0143 0.0141
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.031 0.2363
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Thioredoxin reductase 0.0047 0.0072 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0037 0.0035
Plasmodium falciparum tyrosine kinase-like protein 0.0066 0.0143 0.1217
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.031 0.0691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0037 0.0035
Schistosoma mansoni inositol monophosphatase 0.0037 0.0032 0.0032
Schistosoma mansoni tyrosine kinase 0.1368 0.5159 0.5159
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.004 0.0042 0.0042
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi basement membrane proteoglycan precursor 0.0068 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0075 0.0075
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0038 0.0038
Schistosoma mansoni tyrosine kinase 0.0134 0.0407 0.0407
Schistosoma mansoni tyrosine kinase 0.1368 0.5159 0.5159
Brugia malayi conserved hypotetical protein 0.0092 0.0245 0.0245
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0037 0.0037
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0245 0.0244
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0076 0.0183 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.007 0.0159 0.0315
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Brugia malayi Protein kinase domain containing protein 0.0106 0.0296 0.0296
Schistosoma mansoni nephrin 0.0279 0.0963 0.0963
Brugia malayi Variant SH3 domain containing protein 0.004 0.0042 0.0042
Schistosoma mansoni basigin related 0.0068 0.015 0.015
Brugia malayi Steroid receptor seven-up type 2 0.0196 0.0644 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0113 0.0538
Onchocerca volvulus 0.0048 0.0075 0.0106
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0038 0.0255
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0075 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0104 0.0288 0.0288
Schistosoma mansoni nephrin 0.0118 0.0343 0.0343
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Echinococcus granulosus GPCR family 2 0.0049 0.0078 0.0076
Echinococcus multilocularis cpg binding protein 0.003 0.0006 0.0005
Toxoplasma gondii ABC1 family protein 0.0039 0.0038 0.0087
Loa Loa (eye worm) PDE1B protein 0.0209 0.0694 0.0694
Schistosoma mansoni kinase 0.0059 0.0118 0.0118
Schistosoma mansoni biogenic amine receptor 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.0066 0.0143 0.108
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0057 0.0057
Brugia malayi Fibronectin type III domain containing protein 0.0231 0.0777 0.0777
Onchocerca volvulus 0.0048 0.0075 0.0106
Echinococcus granulosus orexin receptor type 2 0.0038 0.0037 0.0035
Onchocerca volvulus 0.0106 0.0296 0.0421
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0351 0.0351
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) TK/FAK protein kinase 0.0066 0.0143 0.0143
Echinococcus granulosus cyclin dependent kinase 0.0223 0.0749 0.0747
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0134 0.0407 0.0405
Echinococcus multilocularis activin receptor type 0.0074 0.0175 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0749 0.0749
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0143 0.0685
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0037 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0082 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0196 0.0644 0.0644
Onchocerca volvulus 0.0106 0.0296 0.0421
Schistosoma mansoni tyrosine kinase 0.0134 0.0407 0.0407
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.0486 0.0486
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0123 0.0121
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.1472 0.147
Echinococcus multilocularis tyrosine protein kinase Src42A 0.025 0.0853 0.0851
Echinococcus multilocularis raf serine:threonine protein kinase 0.0282 0.0977 0.0976
Schistosoma mansoni cell adhesion molecule 0.0116 0.0335 0.0335
Echinococcus multilocularis neuroglian 0.0118 0.0343 0.0341
Echinococcus multilocularis bloom syndrome protein 0.0048 0.0074 0.0072
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0196 0.0644 0.0644
Echinococcus granulosus down syndrome cell adhesion 0.0048 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.1033 0.387 0.387
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0296 0.103 0.1029
Echinococcus granulosus N chimaerin 0.0047 0.0071 0.0069
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0223 0.0749 0.0749
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0066 0.0143 0.0141
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0321 0.1126 0.865
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0038 0.0015
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.1081 0.4056 0.4056
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0066 0.0143 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.058 0.2818
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Onchocerca volvulus 0.0066 0.0143 0.0203
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus granulosus raf serine:threonine protein kinase 0.0282 0.0977 0.0976
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0196 0.0644 0.0644
Echinococcus multilocularis suppressor of cytokine signaling 6 0.004 0.0042 0.004
Echinococcus multilocularis FL cytokine receptor 0.0066 0.0143 0.0141
Schistosoma mansoni nuclear hormone receptor 0.0196 0.0644 0.0644
Schistosoma mansoni protein kinase 0.0074 0.0175 0.0175
Echinococcus granulosus protein tyrosine kinase 0.0066 0.0143 0.0141
Onchocerca volvulus 0.0038 0.0037 0.0052
Echinococcus multilocularis serotonin receptor 0.0038 0.0037 0.0035
Echinococcus granulosus tyrosine protein kinase otk 0.0116 0.0335 0.0334
Schistosoma mansoni microsomal glutathione s-transferase 0.008 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0066 0.0143 0.0143
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.1081 0.4056 0.4054
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0134 0.0406 0.093
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0107 0.0107
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0092 0.0245 0.0245
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0041 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.031 0.1498
Brugia malayi Prion-like- 0.0048 0.0075 0.0075
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0072 0.0668
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.0288 0.0288
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0041 0.004
Schistosoma mansoni opsin-like receptor 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0103 0.0285 0.0405
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0038 0.0172
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0066 0.0143 0.0141
Mycobacterium tuberculosis Conserved protein 0.0039 0.0038 0.0255
Echinococcus granulosus single minded 2 0.0036 0.0028 0.0026
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0875 0.3262 0.3261
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.0486 0.0486
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Schistosoma mansoni titin 0.0048 0.0075 0.0075
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0215 0.0719 0.0719
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0159 0.0762
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.031 0.0691
Brugia malayi Dopamine receptor protein 1 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Plasmodium vivax SET domain protein, putative 0.0329 0.1156 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0196 0.0644 0.0643
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0044 0.0057 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0037 0.0035
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0048 0.0075 0.0073
Onchocerca volvulus 0.0072 0.0165 0.0234
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0066 0.0143 0.0346
Echinococcus granulosus thyroid hormone receptor alpha 0.0092 0.0245 0.0244
Onchocerca volvulus 0.005 0.0082 0.0117
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0099 0.0099
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Echinococcus granulosus tyrosine protein kinase Fyn 0.025 0.0853 0.0851
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0174 0.0172
Schistosoma mansoni tyrosine kinase 0.025 0.0853 0.0853
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0116 0.0335 0.0334
Schistosoma mansoni amine GPCR 0.0038 0.0037 0.0037
Onchocerca volvulus 0.0031 0.001 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0032 0.0143
Echinococcus multilocularis tyrosine protein kinase Abl 0.0214 0.0712 0.071
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni lipoxygenase 0.0103 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Onchocerca volvulus 0.0092 0.0245 0.0349
Schistosoma mansoni septate junction protein 0.0068 0.015 0.015
Echinococcus granulosus tyrosine protein kinase Lyn 0.0258 0.0884 0.0883
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0106 0.0106
Brugia malayi Tyrosine-protein kinase PR2 0.0066 0.0143 0.0143
Brugia malayi neuropeptide F receptor 0.0038 0.0037 0.0037
Brugia malayi SH2 domain containing protein 0.004 0.0042 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Echinococcus granulosus signal transduction protein lnk realted 0.004 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0008 0.0006
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0106 0.0296 0.0294
Echinococcus granulosus tyrosine protein kinase Src42A 0.025 0.0853 0.0851
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0114 0.0329 0.0327
Trypanosoma brucei fructose-1,6-bisphosphatase 0.1081 0.4056 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.0307 0.0684
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0134 0.0406 0.093
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0037 0.0052
Loa Loa (eye worm) hypothetical protein 0.0116 0.0335 0.0335
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.031 0.069
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0037 0.0035
Onchocerca volvulus Protein ultraspiracle homolog 0.0196 0.0644 0.0916
Brugia malayi Variant SH3 domain containing protein 0.0047 0.0071 0.0071
Echinococcus granulosus SH2 motif 0.004 0.0042 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) TK protein kinase 0.0221 0.0742 0.0742
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0047 0.0071 0.0069
Loa Loa (eye worm) STAT protein 0.004 0.0042 0.0042
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.007 0.0159 0.0157
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus microsomal glutathione S transferase 3 0.008 0.0198 0.0196
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0033 0.0017 0.0015
Loa Loa (eye worm) inositol-1 0.0037 0.0032 0.0032
Onchocerca volvulus 0.1731 0.6559 0.9327
Echinococcus multilocularis neuropeptide s receptor 0.0489 0.1774 0.1772
Echinococcus granulosus allatostatin A receptor 0.0038 0.0037 0.0035
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0041 0.004
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0121 0.0356 0.0354
Brugia malayi Inositol-1 0.0037 0.0032 0.0032
Trichomonas vaginalis protein tyrosine kinase, putative 0.0066 0.0143 0.0685
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0545 0.2646
Schistosoma mansoni slit 0.0048 0.0075 0.0075
Schistosoma mansoni titin 0.0048 0.0075 0.0075
Brugia malayi hypothetical protein 0.0086 0.0222 0.0222
Schistosoma mansoni tensin 0.004 0.0042 0.0042
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0041 0.0338
Brugia malayi hypothetical protein 0.0029 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.031 0.0308
Brugia malayi C-terminal src kinase protein 1 0.0066 0.0143 0.0143
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0076 0.0183 0.0181
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.1829 0.1828
Brugia malayi hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0028 0.0026
Schistosoma mansoni tyrosine kinase 0.0164 0.0522 0.0522
Trypanosoma brucei cAMP-specific phosphodiesterase 0.007 0.0159 0.0315
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0033 0.0014 0.0102
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0749 0.3642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0434 0.0434
Brugia malayi hypothetical protein 0.0164 0.052 0.052
Echinococcus granulosus titin 0.0048 0.0075 0.0073
Onchocerca volvulus Peroxidasin homolog 0.0048 0.0075 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis set domain proteins, putative 0.0266 0.0913 0.4445
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0082
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0032 0.0143
Onchocerca volvulus 0.0041 0.0047 0.0067
Schistosoma mansoni survival motor neuron protein 0.0103 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0002
Brugia malayi Protein set-1 0.0329 0.1156 0.1156
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0074 0.0175 0.0355
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Onchocerca volvulus 0.0048 0.0075 0.0106
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0075
Schistosoma mansoni tyrosine kinase 0.0182 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0143 0.0143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0321 0.1126 0.5485
Schistosoma mansoni hypothetical protein 0.0059 0.0116 0.0116
Loa Loa (eye worm) glutaminase 2 0.0561 0.2052 0.2052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0068 0.015 0.0148
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0025 0.011
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0066 0.0143 0.0685
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Loa Loa (eye worm) TK/ALK protein kinase 0.0311 0.1086 0.1086
Loa Loa (eye worm) hypothetical protein 0.0106 0.0297 0.0297
Loa Loa (eye worm) SH2 domain-containing protein 0.004 0.0042 0.0042
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0196 0.0644 0.0644
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0076 0.0184 0.0184
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0074 0.0175 0.0424
Schistosoma mansoni cell adhesion molecule 0.0048 0.0075 0.0075
Brugia malayi SRC-1 0.025 0.0853 0.0853
Entamoeba histolytica receptor protein kinase, putative 0.0066 0.0143 0.108
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0104 0.0288 0.0286
Echinococcus multilocularis sex peptide receptor 0.0038 0.0037 0.0035
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0037 0.0035
Brugia malayi MAP kinase sur-1 0.0108 0.0307 0.0307
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0068 0.015 0.0148
Brugia malayi Myb-like DNA-binding domain containing protein 0.0048 0.0075 0.0075
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.025 0.0853 0.0851
Echinococcus granulosus peroxidasin 0.0116 0.0335 0.0334
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0196 0.0644 0.0644
Echinococcus multilocularis Immunoglobulin 0.0068 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.0104 0.0288 0.0288
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.1033 0.387 0.3869
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis SH2 motif 0.004 0.0042 0.004
Brugia malayi tailless protein 0.0092 0.0245 0.0245
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0235 0.0794 0.0794
Brugia malayi Serotonin receptor 0.0038 0.0037 0.0037
Brugia malayi Pre-SET motif family protein 0.0235 0.0794 0.0794
Schistosoma mansoni protein kinase 0.0066 0.0143 0.0143
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0066 0.0143 0.0203
Loa Loa (eye worm) hypothetical protein 0.0329 0.1156 0.1156
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0057 0.0055
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0048 0.0074 0.0546
Brugia malayi follicle stimulating hormone receptor 0.0169 0.0539 0.0539
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.1829 0.1828
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0297 0.0297
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0196 0.0644 0.0644
Loa Loa (eye worm) beta-lactamase 0.0039 0.0038 0.0038
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0296 0.0296
Loa Loa (eye worm) TK/FER protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.0307 0.0305
Onchocerca volvulus 0.0029 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0196 0.0644 0.0643
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Echinococcus granulosus titin 0.0058 0.0114 0.0112
Echinococcus multilocularis natriuretic peptide receptor 1 0.0066 0.0143 0.0141
Echinococcus granulosus activin receptor type 0.0074 0.0175 0.0173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0076 0.0183 0.0445
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Echinococcus granulosus suppressor of cytokine signaling 6 0.004 0.0042 0.004
Plasmodium vivax serine/threonine kinase-1, putative 0.025 0.0854 0.7381
Loa Loa (eye worm) hypothetical protein 0.0231 0.0777 0.0777
Echinococcus multilocularis twitchin 0.0056 0.0106 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.031 0.1498
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) disorganized muscle protein 1 0.0048 0.0075 0.0075
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0078 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0977 0.0977
Loa Loa (eye worm) protein kinase domain-containing protein 0.0066 0.0143 0.0143
Brugia malayi bone morphogenetic protein type 1 receptor 0.0066 0.0143 0.0143
Echinococcus granulosus neuropeptide receptor A26 0.0489 0.1774 0.1772
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Brugia malayi hypothetical protein 0.0066 0.0143 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.031 0.15
Schistosoma mansoni titin 0.005 0.0082 0.0082
Brugia malayi Immunoglobulin domain containing protein 0.0068 0.015 0.015
Schistosoma mansoni amine GPCR 0.0038 0.0037 0.0037
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0174 0.0559 0.0557
Echinococcus multilocularis roundabout 2 0.0346 0.1224 0.1222
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0037 0.0035
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0037 0.0035
Echinococcus multilocularis FTZ F1 alpha 0.0196 0.0644 0.0643
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.025 0.0854 0.2044
Schistosoma mansoni hypothetical protein 0.0068 0.015 0.015
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0038 0.0306
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Schistosoma mansoni loxhd1 0.004 0.0041 0.0041
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0075 0.0075
Echinococcus granulosus tyrosine kinase 0.0221 0.0742 0.074
Trichomonas vaginalis protein kinase atn1, putative 0.0066 0.0143 0.0685
Entamoeba histolytica hypothetical protein 0.0066 0.0143 0.108
Entamoeba histolytica cell division protein kinase 2, putative 0.0223 0.0749 0.5743
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0066 0.0143 0.108
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis geminin 0.034 0.1198 0.1196
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0164 0.0522 0.052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Loa Loa (eye worm) nuclear hormone receptor 0.0092 0.0245 0.0245
Echinococcus granulosus retinal guanylyl cyclase 2 0.0066 0.0143 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0196 0.0644 0.0644
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0037 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni tyrosine kinase 0.0066 0.0143 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0205 0.0205
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Onchocerca volvulus 0.0057 0.0108 0.0154
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0353 0.7051
Echinococcus granulosus SH2 domain containing adapter protein F 0.004 0.0042 0.004
Onchocerca volvulus 0.0057 0.0107 0.0153
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0037 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0037 0.0037
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0353 0.4081
Loa Loa (eye worm) hypothetical protein 0.0495 0.1795 0.1795
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.0307 0.0684
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Echinococcus multilocularis tyrosine protein kinase otk 0.0116 0.0335 0.0334
Schistosoma mansoni peroxidasin 0.0068 0.015 0.015
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0068 0.0153 0.0153
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0037 0.0035
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0245 0.0245
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0032 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0196 0.0644 0.0643
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0025
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0041 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0434 0.0434
Brugia malayi Sex muscle abnormal protein 5 0.0068 0.0153 0.0153
Schistosoma mansoni tyrosine kinase 0.0106 0.0296 0.0296
Echinococcus multilocularis somatostatin receptor 0.0038 0.0037 0.0035
Brugia malayi hypothetical protein 0.0104 0.0288 0.0288
Echinococcus granulosus fibroblast growth factor receptor 4 0.0164 0.0522 0.052
Plasmodium falciparum thioredoxin reductase 0.0047 0.0072 0.0601
Onchocerca volvulus 0.0048 0.0075 0.0106
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0038 0.0037 0.0037
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0221 0.0742 0.074
Echinococcus granulosus suppressor of cytokine signaling 7 0.004 0.0042 0.004
Plasmodium vivax SET domain protein, putative 0.0044 0.0057 0.0472
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0143 0.0143
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0066 0.0143 0.0143
Onchocerca volvulus 0.0066 0.0143 0.0203
Brugia malayi ORL1-like opioid receptor 0.0038 0.0037 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0888 0.4323
Schistosoma mansoni adenoreceptor 0.0038 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.001 0.001
Echinococcus granulosus netrin receptor unc 5 0.0082 0.0205 0.0204
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0306 0.3515
Loa Loa (eye worm) TK/RYK protein kinase 0.0066 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0075
Loa Loa (eye worm) SH2 domain-containing protein 0.004 0.0042 0.0042
Onchocerca volvulus 0.0066 0.0143 0.0203
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0159 0.0762
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0037 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0143 0.108
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0037 0.0035
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0107 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0037 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0066 0.0143 0.108
Echinococcus granulosus fmrfamide receptor 0.0038 0.0037 0.0035
Loa Loa (eye worm) TK protein kinase 0.0066 0.0143 0.0143
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0037 0.0035
Entamoeba histolytica tyrosin kinase, putative 0.0066 0.0143 0.108
Echinococcus multilocularis protein tyrosine kinase 0.0066 0.0143 0.0141
Schistosoma mansoni tyrosine kinase 0.1434 0.5413 0.5413
Onchocerca volvulus 0.0033 0.0017 0.0024
Echinococcus granulosus g protein coupled receptor 0.0038 0.0037 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus granulosus SHC transforming protein 3 0.004 0.0042 0.004
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0031 0.001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0196 0.0644 0.0644
Brugia malayi beta-lactamase family protein 0.0039 0.0038 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0335 0.0335
Brugia malayi Protein kinase domain containing protein 0.0066 0.0143 0.0143
Echinococcus granulosus beta-adrenergic receptor kinase 0.0031 0.001 0.0008
Brugia malayi sulfakinin receptor protein 0.0038 0.0037 0.0037
Echinococcus granulosus intermediate filament protein 0.0057 0.0107 0.0106
Echinococcus multilocularis SH2 motif 0.004 0.0042 0.004
Trichomonas vaginalis TKL family protein kinase 0.0066 0.0143 0.0685
Schistosoma mansoni tyrosine kinase 0.0873 0.3254 0.3254
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0196 0.0644 0.0643
Loa Loa (eye worm) hypothetical protein 0.0092 0.0245 0.0245
Echinococcus granulosus SH2 motif 0.004 0.0042 0.004
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.031 0.0308
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.1081 0.4056 1
Schistosoma mansoni neuropeptide receptor 0.0038 0.0037 0.0037
Mycobacterium leprae Probable lipase LipE 0.0039 0.0038 0.044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0434 0.0432
Trypanosoma brucei cdc2-related kinase 1 0.0223 0.0749 0.1782
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.025 0.0854 0.2044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0213 0.0708 0.0708
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0196 0.0644 0.0644

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 19.95262315 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) 4.7444 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (ADMET) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Firefly Luciferase. (Class of assay: confirmatory) [Related pubchem assays: 2309 (Probe Summary for Inhibitors and Stabilizers of Firefly Luciferase)] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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